|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Reduning injection for fever, rash, and ulcers in children with mild hand, foot, and mouth disease: a randomized controlled clinical study显示文摘OBJECTIVE: To assess the efficacy and safety of Reduning injection for fever, rash, and ulcers in children with mild hand, foot, and mouth disease(HFMD). METHODS: A stratified-block randomized, double-blind, parallel-controlled, and multicenter clinical trial was conducted with 360 patients in five hospitals across China: Quanzhou Children's Hospital, Shijiazhuang No. 5 Hospital, Shanghai Public Health Centre, Hunan Provincial Children's Hospital, and Kaifeng Children's Hospital. Patients were randomized into three groups with 120 in each. Group A was treated with Western Medicine, group B with Reduning injection, a Chinese herbal medicine, and group C with both Reduning injection and Western Medicine. Results were compared for treatment efficacy and safety on HFMD. The clinical outcomes were observed as follows: fever and onset time of antifebrile effect(time to bring the body temperature down ≥0.5℃ after medication); cumulative time for fever recovery(body temperature recovering to normal and lasting more than 24 h without medication); cumulative time for rash disappearance(without new rashes or ulcers appearing and the original ones fading away); and cumulative time for mouth ulcer disappearance. RESULTS: For the onset time of the antifebrile effect, there was no statistical difference between groups A and B(P>0.05) and groups B and C(P> 0.05). However, there was a statistical difference between groups A and C(P<0.05), and the effect in group C was the best. For the cumulative time for rash disappearance, there was no statistical difference between groups A and B(P>0.05). There were statistical differences between groups A and C, and groups B and C(P<0.05), and the effect in group C was the best. For the cumulative time for mouth ulcers disappearance, there were no statistical differences among the three groups(P>0.05). CONCLUSION: Reduning injection with Western Medicine for symptomatic treatment is most effective for mild HFMD. No adverse reactions were observed. | Guoliang Zhang Jie Zhao Liyun He Shiyan Yan Ziqiang Zhuo Haojie Zheng Yongping Mu Shuangjie Li Xi Zhang Jihan Huang Xiuhui Li Jianping Liu Hehe Wan Chaoyu Wei Wei Xiao | 2013 | Journal of Traditional Chinese Medicine2013，33，6： | 7 |
| 2 | Xiyanping injection therapy for children with mild hand foot and mouth disease:a randomized controlled trial显示文摘OBJECTIVE: To evaluate the clinical effects of Xiyan-ping injection intervention in pediatric patients with mild hand foot and mouth disease(HFMD).METHODS: A total of 329 patients were stratified and block-randomized for symptomatic treatment of HFMD and assigned to one of the following groups: Western Medicine(group A, n = 103), Xiyanping injection(group B, n = 109), or Xiyanping injection and symptomatic treatment using Western Medicine(group C, n = 117). During the trial, fever,rash, ulcers of the mouth were observed among participants in each group before and after treatment, and conversion rates from mild to severe HFMD were measured.RESULTS: After 3-7 days' treatment, no significant differences in the conversion rates from mild to severe HFMD were observed among the three groups(P > 0.05). There was a significantly low number of patients with the onset time of antifebrile effect,vanished time of hand and foot rashes and cumulative time for the ulcers in the mouth vanished,among the three groups(P < 0.05, P < 0.01). The onset time of antifebrile effect of patients in groups B and C were markedly shorter compared with those in group A(P < 0.05, P < 0.01); there was no statically significant difference observed between groups B and C(P > 0.05). No significant differences were observed in the time for body temperature recovery among the three groups(P > 0.05). There were no significant differences in adverse effects among the three groups(P > 0.05).CONCLUSION: Xiyanping injection together with use of Western Medicine is most effective for symptomatic treatment of mild HFMD. No severe adverse reactions were observed. | Zhang Guoliang He Liyun Tang Liuping Yang Tong Zou Xinying Zhu Qingxiong Yan Shiyan Hou Yong Huang Baoju Zhao Jindong Li Yan Huang Jihan | 2017 | Journal of Traditional Chinese Medicine2017，37，3： | 4 |
| 3 | Zircon U-Pb geochronology of tuffite beds in the Baishugou Formation:Constraints on the revision of Ectasian System at the southern margin of the North China Craton显示文摘The Xiamaling Formation of 1.4–1.35 Ga in Jixian Section and adjoining areas represents a unique Ectasian Period(Mesoproterozoic)sedimentary sequence in the North China Craton(NCC).Studies carried out during the last decade have contributed significantly in improving our understanding about the Ectasian sedimentation tectonics in the NCC during this transitional interval between the breakup of Supercontinent Columbia and the assembly of Rodinia.The present study reports,for the first time,tuffite beds interlayered with carbonaceous-siliceous slate-phyllite in the upper Baishugou Formation(western Henan Province),at the southern margin of NCC.The LA-MC-ICPMS U-Pb geochronology of zircons from two tuffite samples has yielded almost identical ages of 1330±10 Ma(MSWD=0.43,N=38)and 1332±10 Ma(MSWD=0.90,N=24),that constrain a 1.33 Ga depositional age(Ectasian Period)for the Baishugou Formation.A close similarity in lithological characteristics and their respective superimposed lithostratigraphic relationships of the Baishugou and Xiamaling formations,underline a comparable depositional environment for them.The high-precision geochronology data on the Baishugou Formation would stimulate a relook into the Meso-Neoproterozoic chronostratigraphic framework of the NCC,and further research would lead to a comprehensive understanding of the geological evolution of the NCC during Ectasian Period and its correlation with analogous global events. | Xiyan ZHU Shiyan WANG Wenbo SU Taiping ZHAO Lanyin PANG Mingguo ZHAI | 2020 | Science China Earth Sciences2020，63，11： | 4 |
| 4 | Shakedown Criterion Employing Actual Residual Stress Field and Its Application in Numerical Shakedown Analysis显示文摘Construction of the static admissible residual stress field and searching the optimal field are key tasks in the shakedown analysis methods applying the static theorem. These methods always meet dimension obstacles when dealing with complex problems. In this paper, a novel shakedown criterion is proposed employing actual residual stress field based on the static shakedown theorem. The actual residual stress field used here is produced under a specified load path, which is a sequence of proportional loading and unloading from zero to all the vertices of the given load domain. This ensures that the shakedown behavior in the whole load domain can be determined based on the theorem proposed by K?nig. The shakedown criterion is then implemented in numerical shakedown analysis. The actual residual stress fields are calculated by incremental finite element elastic-plastic analysis technique for finite deformation under the specified load path with different load levels. The shakedown behavior and the shakedown limit load are determined according to the proposed criterion. The validation of the criterion is performed by a benchmark shakedown example, which is a square plate with a central hole under biaxial loading. The results are consistent with existing results in the literatures and are validated by full cyclic elastic-plastic finite element analysis. The numerical shakedown analysis applying the proposed criterion avoids processing dimension obstacles and performing full cyclic elastic-plastic analysis under arbitrary load paths which should be accounted for appearing. The effect of material model and geometric changes on shakedown behavior can be considered conveniently. | ZOU Zongyuan GUO Baofeng LI Yinxiao JIN Miao ZHAO Shiyan | 2015 | Chinese Journal of Mechanical Engineering2015，28，5： | 4 |
| 5 | Towards carbon neutrality:A study on China's long-term low-carbon transition pathways and strategies显示文摘As the world's biggest carbon dioxide(CO_(2))emitter and the largest developing country,China faces daunting challenges to peak its emissions before 2030 and achieve carbon neutrality within 40 years.This study fully considered the carbon-neutrality goal and the temperature rise constraints required by the Paris Agreement,by developing six long-term development scenarios,and conducting a quantitative evaluation on the carbon emissions pathways,energy transformation,technology,policy and investment demand for each scenario.This study combined both bottom-up and top-down methodologies,including simulations and analyses of energy consumption of end-use and power sectors(bottom-up),as well as scenario analysis,investment demand and technology evaluation at the macro level(top-down).This study demonstrates that achieving carbon neutrality before 2060 translates to significant efforts and overwhelming challenges for China.To comply with the target,a high rate of an average annual reduction of CO_(2) emissions by 9.3%from 2030 to 2050 is a necessity,which requires a huge investment demand.For example,in the 1.5℃ scenario,an investment in energy infrastructure alone equivalent to 2.6%of that year's GDP will be necessary.The technological pathway towards carbon neutrality will rely highly on both conventional emission reduction technologies and breakthrough technologies.China needs to balance a long-term development strategy of lower greenhouse gas emissions that meets both the Paris Agreement and the long-term goals for domestic economic and social development,with a phased implementation for both its five-year and long-term plans. | Jiankun He Zheng Li Xiliang Zhang Hailin Wang Wenjuan Dong Ershun Du Shiyan Chang Xunmin Ou Siyue Guo Zhiyu Tian Alun Gu Fei Teng Bin Hu Xiu Yang Siyuan Chen Mingtao Yao Zhiyi Yuan Li Zhou Xiaofan Zhao Ying Li Danwei Zhang | 2022 | Environmental Science and Ecotechnology2022，，1： | 2 |
| 6 | E-Commerce Supply Chain Process Optimization Based on Whole-Process Sharing of Internet of Things Identification Technology显示文摘With in-depth development of the Internet of Things(IoT)in various industries,the informatization process of various industries has also entered the fast lane.This article aims to solve the supply chain process problem in e-commerce,focusing on the specific application of Internet of Things technology in e-commerce.Warehousing logistics is an important link in today’s e-commerce transactions.This article proposes a distributed analysis method for RFID-based e-commerce warehousing process optimization and an e-commerce supply chain management process based on Internet of Things technology.This article first introduces the advantages and disadvantages of shared IoT identification technology and the IoT resource sharing platform based on the three-layer abstract data model and representational state transfer(REST)style.Combining actual IoT applications and the characteristics of an existing platform,a REST-based IoT resource sharing platform is proposed.Combined with actual projects,a REST-based IoT resource sharing platform was built,and key technology experiments were conducted for verification.Finally,optimizing the e-commerce supply chain management process under Internet of Things technology and explaining the advantages of optimized e-commerce supply chain management are discussed.Research on this subject provides a theoretical basis for the application of the Internet of Things in e-commerce and has practical significance and practical value for managing service capabilities and service levels in e-commerce. | Shiyan Xu Jun Chen Maoguo Wu Chenyang Zhao | 2021 | Computer Modeling in Engineering & Sciences2021，，2： | 2 |
| 7 | Biofuels development in China: Technology options and policies needed to meet the 2020 target 显示文摘 | CHANG Shiyan ZHAO Lili Timilsina G R | 2012 | Energy Policy2012，51，： | 1 |
| 8 | A multi-direction extracting method of the building contour based on point cloud of the terrestrial laser scanner显示文摘 | Zhang Xuewen Zhao Xian Wei Shiyan | 2008 | The International Archives of the Photogrammetry Remote Sensing and Spatial Information Sciences2008，37，5： | 1 |
| 9 | The persistent prevalence and evolution of cross-family recombinant coronavirus GCCDC1 among a bat population:a two-year follow-up显示文摘Bats are connected with the increasing numbers of emerging and re-emerging viruses that may break the species barrier and spread into the human population. Coronaviruses are one of the most common viruses discovered in bats, which were considered as the natural source of recent human-susceptible coronaviruses, i.e. SARS-COV and MERS-CoV. Our previous study reported the discovery of a bat-derived putative cross-family recombinant coronavirus with a reovirus gene p10, named as Ro-BatCoV GCCDC1. In this report, through a two-year follow-up of a special bat population in one specific cave of south China, we illustrate that Ro-BatCoV GCCDC1 persistently circulates among bats. Notably, through the longitudinal observation, we identified the dynamic evolution of Ro-BatCoV GCCDC1 in bats represented by continuously recombination events. Our study provides the first glimpse of the virus evolution in one longitudinally observed bat population cohort and underlines the surveillance and pre-warning of potential interspecies transmittable viruses in bats. | Joseph O.Obameso Hong Li Hao Jia Min Han Shiyan Zhu Canping Huang Yuhui Zhao Min Zhao Yu Bai Fei Yuan Honglan Zhao Xia Peng Wen Xu Wenjie Tan Yingze Zhao Kwok-Yung Yuen William J.Liu Lin Lu George F.Gao | 2017 | Science China(Life Sciences)2017，60，12： | 1 |
| 10 | Comprehensive report on China's Long-Term Low-Carbon Development Strategies and Pathways显示文摘1.Introduction 2020 is an unusual year in which the COVID-19 pandemic has raged through the globe,infecting tens of millions of people and killing hundreds of thousands.The pandemic has not only wreaked havoc on public health systems,economic activities,and people's lives,but also has greatly affected and will continue to reshape the world's political,economic,and trade patterns. | Jiankun He Zheng Li Xiliang Zhang Hailin Wang Wenjuan Dong Shiyan Chang Xunmin Ou Siyue Guo Zhiyu Tian Alun Gu Fei Teng Xiu Yang Siyuan Chen Mingtao Yao Zhiyi Yuan Li Zhou Xiaofan Zhao | 2020 | Chinese Journal of Population,Resources and Environment2020，18，4： | 1 |
| 11 | The genomic characteristics and pathogenicity of a mammalian orthoreovirus within a new lineage from wild pika in plateau显示文摘Emerging and re-emerging viruses from wild animals have seriously threatened the health of humans and domesticated animals in recent years.Herein,we isolated a new mammalian orthoreovirus(MRV),Pika/MRV/GCCDC7/2019(PMRV-GCCDC7),in the Qinghai-Tibet Plateau wild pika(Ochotona curzoniae).Though the PMRVGCCDC7 shows features of a typical reovirus with ten gene segments arranged in 3:3:4 in length,the virus belongs to an independent evolutionary branch compared to other MRVs based on phylogenetic tree analysis.The results of cellular susceptibility,species tropism,and replication kinetics of PMRV-GCCDC7 indicated the virus could infect four human cell lines(A549,Huh7,HCT,and LoVo)and six non-human cell lines,including Vero-E6,LLCMK2,BHK-21,N2a,MDCK,and RfKT cell,derived from diverse mammals,i.e.monkey,mice,canine and bat,which revealed the potential of PMRV-GCCDC7 to infect a variety of hosts.Infection of BALB/c mice with PMRVGCCDC7 via intranasal inoculation led to relative weight loss,lung tissue damage and inflammation with the increase of virus titer,but no serious respiratory symptoms and death occurred.The characterization of the new reovirus from a plateau-based wild animal has expanded our knowledge of the host range of MRV and provided insight into its risk of trans-species transmission and zoonotic diseases. | Kexin Zong Yuanyuan Guo Jingdong Song Maoshun Liu Junfeng Hao Jie Zhang Xin Li Shiyan Zhu Shuting Huo Ziqian Xu Peipei Liu Yingze Zhao Yuhai Bi Jiapeng Qu George F.Gao Jun Liu | 2023 | Virologica Sinica2023，38，6： | 0 |
| 12 | Reversibly immortalized keratinocytes(iKera)facilitate re-epithelization and skin wound healing:Potential applications in cell-based skin tissue engineering显示文摘Skin injury is repaired through a multi-phase wound healing process of tissue granulation and re-epithelialization.Any failure in the healing process may lead to chronic non-healing wounds or abnormal scar formation.Although significant progress has been made in developing novel scaffolds and/or cell-based therapeutic strategies to promote wound healing,effective management of large chronic skin wounds remains a clinical challenge.Keratinocytes are critical to re-epithelialization and wound healing.Here,we investigated whether exogenous keratinocytes,in combination with a citrate-based scaffold,enhanced skin wound healing.We first established reversibly immortalized mouse keratinocytes(iKera),and confirmed that the iKera cells expressed keratinocyte markers,and were responsive to UVB treatment,and were non-tumorigenic.In a proof-of-principle experiment,we demonstrated that iKera cells embedded in citrate-based scaffold PPCN provided more effective re-epithelialization and cutaneous wound healing than that of either PPCN or iKera cells alone,in a mouse skin wound model.Thus,these results demonstrate that iKera cells may serve as a valuable skin epithelial source when,combining with appropriate biocompatible scaffolds,to investigate cutaneous wound healing and skin regeneration. | Jiamin Zhong Hao Wang Ke Yang Huifeng Wang Chongwen Duan Na Ni Liqin An Yetao Luo Piao Zhao Yannian Gou Shiyan Sheng Deyao Shi Connie Chen William Wagstaff b Bryce Hendren-Santiago b Rex C.Haydon b Hue H.Luu b Russell R.Reid Sherwin HHo Guillermo A.Ameer Le Shen Tong-Chuan He Jiaming Fan | 2022 | Bioactive Materials2022，7，3： | 0 |
| 13 | Dynamic Routing of Multiple QoS-Required Flows in Cloud-Edge Autonomous Multi-Domain Data Center Networks显示文摘The 6th generation mobile networks(6G)network is a kind of multi-network interconnection and multi-scenario coexistence network,where multiple network domains break the original fixed boundaries to form connections and convergence.In this paper,with the optimization objective of maximizing network utility while ensuring flows performance-centric weighted fairness,this paper designs a reinforcement learning-based cloud-edge autonomous multi-domain data center network architecture that achieves single-domain autonomy and multi-domain collaboration.Due to the conflict between the utility of different flows,the bandwidth fairness allocation problem for various types of flows is formulated by considering different defined reward functions.Regarding the tradeoff between fairness and utility,this paper deals with the corresponding reward functions for the cases where the flows undergo abrupt changes and smooth changes in the flows.In addition,to accommodate the Quality of Service(QoS)requirements for multiple types of flows,this paper proposes a multi-domain autonomous routing algorithm called LSTM+MADDPG.Introducing a Long Short-Term Memory(LSTM)layer in the actor and critic networks,more information about temporal continuity is added,further enhancing the adaptive ability changes in the dynamic network environment.The LSTM+MADDPG algorithm is compared with the latest reinforcement learning algorithm by conducting experiments on real network topology and traffic traces,and the experimental results show that LSTM+MADDPG improves the delay convergence speed by 14.6%and delays the start moment of packet loss by 18.2%compared with other algorithms. | Shiyan Zhang Ruohan Xu Zhangbo Xu Cenhua Yu Yuyang Jiang Yuting Zhao | 2024 | Computers, Materials & Continua2024，78，2： | 0 |
| 14 | Metagenomics analysis identifies oral Streptococcus as potential biomarkers for nasopharyngeal carcinoma显示文摘Nasopharyngeal carcinoma(NPC)is a malignancy originating from the nasopharyngeal epithelial cells.Although some studies have identified potential biomarkers for early diagnosis of NPC based on metabolomics data(Chen et al.,2023;Zhou et al.,2023)and Epstein-Barr virus subtypes(Xu et al.,2019),their effectiveness and applicability need further investigation,particularly when consideringthe roles of oral microbiota. | Yanmin Liu Chengtao Wang Lixiang Xie Shuling Du Li Ding Ying Cui Runzhi Chen Jingxiang Zhang Wan Wang Xi Liu Yan Wang Shiyan Chen Tian Tan Qiaochu Zhao Limei Yin Chunwei Li Yong Chen Tao Ding | 2024 | Journal of Genetics and Genomics2024，51，3： | 0 |
| 15 | Tuning the Charge Transport Property of Naphthalene Diimide Derivatives by Changing the Substituted Position of Fluorine Atom on Molecular Backbone显示文摘Three naphthalene diimides(2,3 and 4)fused with 2-(1,3-dithiol-2-ylidene)-2-fluorophenylacetonitrile moieties were designed and synthesized.Due to the different substituted positions of fluorine atom on the phenyl group,the solution-processed thin films of 2 and 3 operated in air as n-channel transistors,while the films of 4 performed as ambipolar transistors,indicating that the variation of substituted position of fluorine atom on molecular backbone may tune the material’s charge transport behavior. | Xiao Zhang Zhongli Wang Shiyan Chen Zheng Zhao Wei Yuan Huaping Wang Xike Gao | 2014 | Chinese Journal of Chemistry2014，32，10： | 0 |
| 16 | Effects of Astragalus membranaceus on Energy Metabolism and Expression of CNTF Protein in Skeletal Muscle of Exercise-induced Fatigue Rats显示文摘[Objectives]This study was conducted to investigate the effects of Astragalus membranaceus in different groups on energy metabolism and CNTF protein expression in skeletal muscle of exercise-induced fatigue rats.[Methods]Thirty-five clean male SD rats were randomly divided into a normal group,and low-,meddle-and high-dose groups of A.membranaceus aqueous solution,with 7 rats in each group.The low-dose,medium-dose and high-dose groups were given by gavage at 0.65,1.3 and 2.6 g/kg,respectively,while the normal group and the model group were given normal food and water.The weight of rats was observed.The contents of serum urea,lactate,muscle glycogen,liver glycogen and CNTF expression were detected.[Results]After modeling,compared with the normal group,the serum lactate and urea contents of rats in the model group significantly increased(P<0.01),while the muscle glycogen content(P<0.01)and liver glycogen content(P<0.05)of the skeletal muscle significantly decreased.Compared with the model group,the low-,meddle-and high-dose groups of A.membranaceus significantly reduced the levels of lactate and urea in serum(P<0.01),while the levels of muscle glycogen and liver glycogen in the skeletal muscle significantly increased(P<0.01,P<0.05).[Conclusions]This study provides a good research foundation for the treatment of exercise-induced fatigue using traditional Chinese herb A.membranaceus in modern clinical practice. | Yueqi ZHOU Xue ZHANG Zelin ZHAO Yuanxia SHEN Li YANG Song WANG Junying TIAN Sibu MA Shiyan HUANG | 2023 | Agricultural Biotechnology2023，12，6： | 0 |
| 17 | Multi-Criteria Decision-Making for Power Grid Construction Project Investment Ranking Based on the Prospect Theory Improved by Rewarding Good and Punishing Bad Linear Transformation显示文摘Using the improved prospect theory with the linear transformations of rewarding good and punishing bad(RGPBIT),a new investment ranking model for power grid construction projects(PGCPs)is proposed.Given the uncertainty of each index value under the market environment,fuzzy numbers are used to describe qualitative indicators and interval numbers are used to describe quantitative ones.Taking into account decision-maker’s subjective risk attitudes,a multi-criteria decision-making(MCDM)method based on improved prospect theory is proposed.First,the[−1,1]RGPBIT operator is proposed to normalize the original data,to obtain the best andworst schemes of PGCPs.Furthermore,the correlation coefficients between interval/fuzzy numbers and the best/worst schemes are defined and introduced to the prospect theory to improve its value function and loss function,and the positive and negative prospect value matrices of the project are obtained.Then,the optimization model with the maximum comprehensive prospect value is constructed,the optimal attribute weight is determined,and the PGCPs are ranked accordingly.Taking four PGCPs of the IEEERTS-79 node system as examples,an illustration of the feasibility and effectiveness of the proposed method is provided. | Shun Ma Na Yu Xiuna Wang Shiyan Mei Mingrui Zhao Xiaoyu Han | 2023 | Energy Engineering2023，120，10： | 0 |
| 18 | Logistics Factors Affecting Cross-border Ecommerce Implementation显示文摘The purpose of this paper is to provide a structured literature review of cross-border e-logistics research,uncover existing gaps and opportunities,try to find practical strategies to balance logistics costs and service levels,and improve logistics efficiency and customer satisfaction for future cross-border e-logistics research.Meanwhile this paper also uses the real data to test the tradeoff between transportation and warehousing cost.In addition,regression empirical analysis is used to make up for the lack of empirical drawbacks of many articles in the field and the result can be instructive and referential for cross-border e-commerce enterprises to make decisions on weighing logistics cost and service level to improve logistics efficiency. | Jun Chen Shiyan Xu Yuxin Tian Chenyang Zhao | 2020 | 经济管理学刊(中英文版)2020，9，1： | 0 |
| 19 | Predicting Illness Severity and Short-Term Outcomes of COVID-19:A Retrospective Cohort Study in China显示文摘Introduction COVID-19,caused by SARS-CoV-2,is a highly contagious disease.1 By April 8,2020,more than 1,350,000 patients were diagnosed with COVID-19 globally,with more than 79,000 deaths worldwide attributable to the disease.2 Recent clinical data reported that mild and critical patients manifested different symptoms.Most of the mild patients with COVID-19 had symptoms such as fever,cough,and mild pneumonia,whereas the critical cases presented dyspnea,respiratory failure,sepsis,organ dysfunction,and even eventual death. | Chuming Chen Haihui Wang Zhichao Liang Ling Peng Fang Zhao Liuqing Yang Mengli Cao Weibo Wu Xiao Jiang Peiyan Zhang Yinfeng Li Li Chen Shiyan Feng Jianming Li Lingxiang Meng Huishan Wu Fuxiang Wang Quanying Liu Yingxia Liu | 2020 | The Innovation2020，1，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员