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| 1 | Three-dimensional crustal velocity structure model of the middle-eastern north China Craton (HBCrust1.0)显示文摘Lithosphere thinning and destruction in the middle-eastern North China Craton(NCC), a region susceptible to strong earthquakes, is one of the research hotspots in solid earth science. All 42 seismic wide-angle reflection/refraction profiles have been completed in the middle-eastern NCC. We collect all the 2-D profiling results and perform gridding of the velocity and interface depth data, building a 3-D crustal velocity structure model for the middle-eastern NCC, named HBCrust1.0, by using the Kriging interpolation method. Our result shows that the first-arrival times calculated by HBCust1.0 fit well with the observations. The result demonstrates that the upper crust is the main seismogenic layer, and the brittle-ductile transition occurs at depths near interface C(the interface between upper and lower crust). The depth of interface Moho varies beneath the source area of the Tangshan earthquake, and a low-velocity structure is found to extend from the source area to the lower crust. Based on these observations, it can be inferred that stress accumulation responsible for the Tangshan earthquake may have been closely related to the migration and deformation of the mantle materials. Comparisons of the average velocities of the whole crust, the upper and the lower crust show that the average velocity of the lower crust under the central part of the North China Basin(NCB) in the east of the craton is obviously higher than the regional average. This high-velocity probably results from long-term underplating of the mantle magma. | DUAN YongHong WANG FuYun ZHANG XianKang LIN JiYan LIU Zhi LIU BaoFeng YANG ZhuoXin GUO WenBin WEI YunHao | 2016 | Science China Earth Sciences2016，59，7： | 24 |
| 2 | 2-D P-wave velocity structure of lithosphere in the North China tectonic zone: Constraints from the Yancheng-Baotou deep seismic profile显示文摘We obtained the 2-D P-wave velocity structure of the lithosphere in the eastern North China Craton, Shanxi fault subsidence zone, and Yinchuan-Hetao fault subsidence zone by ray tracking technology based on six groups of clearly identified crustal phases and one group of lithospheric interface reflection phases from seismic recording sections of 21 shots along the 1300-km-long Yancheng-Baotou deep seismic wide-angle reflection/refraction profile. The results indicate significant differences between the lithospheric structure east and west of the Taihang Mountains, which is a gravity-gradient zone as well as a zone of abrupt change in lithospheric thickness and a separation zone of different rock components. East of the Taihang Mountains, the Mesozoic and Cenozoic lithospheric structure of the North China Craton has undergone strong reformation and destruction, resulting in the lithosphere thickness decreasing to 70–80 km. The North China Basin has a very thick Cenozoic sedimentary cover and the deepest point of crystalline basement is about 7.0 km, with the crustal thickness decreasing to about 31.0 km. The crystalline basement of the Luxi uplift zone is relatively shallow with a depth of 1.0–2.0 km and crustal thickness of 33.0–35.0 km. The Subei Basin has a thicker Cenozoic sedimentary cover and the bottom of its crystalline basement is at about 5.0–6.0 km with a crustal thickness of 31.0–32.0 km. The Tanlu fault is a deep fracture which cuts the lithosphere with a significant velocity structure difference on either side of the fault. The Tanlu fault plays an important role in the lithospheric destruction in the eastern part of the North China Craton. West of the Taihang Mountains, the crustal thickness increases significantly. The crust thickness beneath the Shanxi fault depression zone is about 46 km, and there is a low-velocity structure with a velocity of less than 6.1 km s?? in the upper part of the middle crust. Combined with other geophysical study results, our data shows that the lithospheric destruction at the Shaanxi-Shanxi fault depression zone and the Yinchuan-Hetao rift surrounding the Ordos block is non-uniform. The lithosphere thickness is about 80–90 km in the Datong-Baotou area, 75–137 km at the Dingxiang-Shenmu region, and about 80–120 km in the Anyang-Yichuan area. The non-uniform lithospheric destruction may be related to the ancient tectonic zone surrounding the Ordos block. This zone experienced multi-period tectonic events in the long-term process of its tectonic evolution and was repeatedly transformed and weakened. The weakening level is related to the interactions with the Ordos block. The continental collision between the Cenozoic India and Eurasia plates and N-E thrusting by the Qinghai Tibet Plateau block is causing further reformation and reduction of the lithosphere. | DUAN YongHong LIU BaoJin ZHAO JinRen LIU BaoFeng ZHANG ChengKe PAN SuZhen LIN JiYan GUO WenBin | 2015 | Science China Earth Sciences2015，58，9： | 14 |
| 3 | Recombinant CC16 protein inhibits the production of pro-inflammatory cytokines via NF-KB and p38 MAPK pathways in LPS-activated RAW264,7 macrophages显示文摘积累的证据显示克莱拉房间 protein-16 (CC16 ) 有反煽动性的功能,尽管深奥分子的小径完全没被阐明。这里,我们评估了效果肿瘤坏死因素 alpha (TNF-) 的表示上的 recombinant 老鼠 CC16 (rCC16 ) , interleukin-6 (IL-6 ) ,和在 lipopolysaccharide (LPS ) 的 IL-8 刺激了老鼠巨噬细胞(RAW264.7 房间) 并且探索了内在的分子的机制。rCC16 在两个禁止了导致 LPS 的 TNF- , IL-6,和 IL-8 表示,这被发现送信人 ribonucleicacid (mRNA ) 水平和蛋白质以一种集中依赖者方式铺平,由即时反向的 transcriptase 聚合酶链反应和连接酶的 immunosorbent 试金示威了。如此的镇压效果被 transcriptional 活动和原子因素(NF ) 的脱氧核糖核酸酸绑定活动的抑制伴随 -B 然而并非使活跃之物蛋白质(AP )-1。西方的污点分析进一步表明 rCC16 禁止了原子 NF-B 和 NF-B 禁止的蛋白质 IB,和 p38 的 cytosolic NF-B, phosphorylation 和减小的减小的增加激活 mitogen 的蛋白质 kinase (MAPK ) 依赖者由在它的 p65 子单元的 Ser276 的 phosphorylation 的 NF-B 激活。而且, rCC16 被发现没另外在c6月N终端 kinase ,c6月,或c-Jun.的原子 translocation 的 phosphorylation 上有效果,TNF-的减小, IL-6 ,并且 IL-8 被颠倒内长的uteroglobin有约束力的蛋白质的水平什么时候被 RNA 干扰在 对待rCC16 、 对待LPS 的 RAW264.7 房间减少。我们的数据建议 rCC16 由在 RAW264.7 房间使 NF-B 和 p38 MAPK 然而并非 AP-1 失去活性压制调停 LPS 的煽动性的调停人 TNF- , IL-6,和 IL-8 生产。 | Min Pang Yangyang Yuan Dong Wang Ting Li Dan Wang Xiaohong Shi Min Guo Chunfang Wang Xinri Zhang Guoping Zheng Baofeng Yu Hailong Wang | 2017 | Acta Biochimica et Biophysica Sinica2017，49，5： | 14 |
| 4 | Acetyl salicylic acid attenuates cardiac hypertrophy through Wnt signaling显示文摘室的肥大是心血管的疾病的事件的一个强大、独立的预言者。低剂量的乙酰水杨酸酸(阿司匹林) 的脉管的性质通过血小板 cyclooxygenase 的不可逆的抑制提供心血管的好处 1;然而,可能的 anti-hypertrophic 性质和阿司匹林的潜在的机制没详细被调查。在这研究,健康野类型的雄的老鼠随机被划分成三个组并且使遭到了到横向的大动脉的收缩(TAC ) 或假冒的操作。操作 TAC 的老鼠与低剂量的阿司匹林的人的等价物被对待(10 mg 吗? | Samuel Chege Gitau Xuelian Li Dandan Zhao Zhenfeng Guo Haihai Liang Ming Qian Lifang Lv Tianshi Li Bozhi Xu Zhiguo Wang Yong Zhang Chaoqian Xu Yanjie Lu Zhiming Du Hongli Shan Baofeng Yang | 2015 | Frontiers of Medicine2015，9，4： | 6 |
| 5 | Shakedown Criterion Employing Actual Residual Stress Field and Its Application in Numerical Shakedown Analysis显示文摘Construction of the static admissible residual stress field and searching the optimal field are key tasks in the shakedown analysis methods applying the static theorem. These methods always meet dimension obstacles when dealing with complex problems. In this paper, a novel shakedown criterion is proposed employing actual residual stress field based on the static shakedown theorem. The actual residual stress field used here is produced under a specified load path, which is a sequence of proportional loading and unloading from zero to all the vertices of the given load domain. This ensures that the shakedown behavior in the whole load domain can be determined based on the theorem proposed by K?nig. The shakedown criterion is then implemented in numerical shakedown analysis. The actual residual stress fields are calculated by incremental finite element elastic-plastic analysis technique for finite deformation under the specified load path with different load levels. The shakedown behavior and the shakedown limit load are determined according to the proposed criterion. The validation of the criterion is performed by a benchmark shakedown example, which is a square plate with a central hole under biaxial loading. The results are consistent with existing results in the literatures and are validated by full cyclic elastic-plastic finite element analysis. The numerical shakedown analysis applying the proposed criterion avoids processing dimension obstacles and performing full cyclic elastic-plastic analysis under arbitrary load paths which should be accounted for appearing. The effect of material model and geometric changes on shakedown behavior can be considered conveniently. | ZOU Zongyuan GUO Baofeng LI Yinxiao JIN Miao ZHAO Shiyan | 2015 | Chinese Journal of Mechanical Engineering2015，28，5： | 4 |
| 6 | Investigation of plateau basin crustal structures and thickening mechanisms in the northeastern margin of the Tibetan plateau显示文摘This paper uses deep seismic sounding (DSS) data to contrast and analyze the crustal structures of three plateau basins (Songpan-Garze, Qaidam, Longzhong) in the northeastern margin of the Qinghai-Xizang (Tibetan) plateau, as well as two stable cratonic basins (Ordos, Sichuan) in its peripheral areas. Plateau basin crustal structures, lithological variations and crustal thickening mechanisms were investigated. The results show that, compared to the peripheral stable cratonic basins, the crystalline crusts of plateau basins in the northeastern margin are up to 10-15 km thicker, and the relative medium velocity difference is about 5% less. The medium velocity change in crustal layers of plateau basin indicates that the upper crust undergoes brittle deformation, whereas the lower crust deforms plastically with low velocity. The middle crust shows a brittle-to-plastic transition zone in this region. Thickening in the lower crust (about 5-10 km), and rheological characteristics that show low- medium velocity (relatively reduced by 7%), suggest that crustal thickening mainly takes place in lower crust in the northeastern margin of the Tibetan plateau. The crust along the northeastern margin shows evidence of wholesale block movement, and crustal shortening and thickening seem to be the main deformation features of this region. The GPS data show that the block motion modes and crustal thickening in the Tibetan plateau is closely related to the peripheral tectonic stress field and motion direction of the Indian plate. The Mani-Yushu- Xianshuihe fold belt along the boundary between the Qiangtang block and the Bayan Har block divides the different plateau thickening tectonic environments into the middle-western plateau, the northeastern margin and the southeastern plateau. | Shixu Jia Zhaofan Xu Zhi Liu Jianshi Zhang Baofeng Liu Jiyan Lin Wenbin Guo | 2012 | Earthquake Science2012，25，5： | 1 |
| 7 | Customizing kernel functions for SVM-based hyperspeetral image classification 显示文摘 | GUO Baofeng STEVE R | 2008 | IEEE Transactions on Image Processing2008，17，4： | 1 |
| 8 | Chronology and paleoenvironmental records of a drill core in the central Tengger Desert of China显示文摘 | Zaijun Li Donghuai Sun Fahu Chen Fei Wang Yuebao Zhang Feng Guo Xin Wang Baofeng Li | 2014 | Quaternary Science Reviews2014，，： | 1 |
| 9 | Band selection for hyperspectral image classification using mutual information 显示文摘 | Guo Baofeng Gunn Steve R Damper R I | 2006 | IEEE Geoscience and Remote Sensing Letters2006，3，4： | 1 |
| 10 | RNA interference therapy for glioblastoma显示文摘 | Dongsheng Guo Baofeng Wang Fuxin Han Ting Lei | 2010 | Expert Opinion on Biological Therapy2010，，6： | 1 |
| 11 | Study on the Changes of the Major Nutrient Elements During Simple Composting Process of Dry Chicken Manure显示文摘[Objectives]This study was conducted to provide a theoretical basis for production and application of chicken manure compost.[Methods]With dry manure as a material,the variations of the major nutrients during simple composting process of dry chicken manure were studied,in order to get the best fermentation method.[Results]Chicken manure should not be preserved wet,but should be preserved after air-drying and fermented before use.Necessary moisture,simple sealing treatment and a certain amount of N element were conducive to simple fermentation of chicken manure.The treatments in which the chicken manure was wrapped around and compacted,added with an appropriate amount of water(50%-60%)and naturally fermented,or was wrapped around and compacted and added with an appropriate amount of water(50%-60%)and 0.2%of urea,were more appropriate for the production directly.[Conclusions]This study provides a theoretical basis for the actual production and application of chicken manure compost. | Jintao XU Longfei LI Lijuan GAO Yong GUO Hai'e ZHANG Minghui JI Baofeng HAO | 2020 | Agricultural Biotechnology2020，9，6： | 1 |
| 12 | Efficient Modeling of an Axial Compressor with Swirl Distortion显示文摘This paper presents a satisfactory numerical strategy to reliably evaluate the three-dimensional large-scale flow feature of multistage axial compressors in response to complex swirl distortion with acceptable computational cost. Under the theoretical framework of the body force method, the guide vanes of a swirl distortion generator and the multiple blade rows of a two-stage low-speed axial compressor are described by distributed source terms instead of a complex body-fitted grid approach. The key flow structure of the paired swirl generated by the swirl generator and the main distributions of flow angle at the rotor outlet of the first stage captured by the model agree well with experimental results, demonstrating the effectiveness of the numerical strategy. Additionally, the interaction process between the steady-state paired swirl and the compressor is clearly revealed by the study. The intensity of the swirl distortion can be greatly reduced after passing through the axial compressor. However, the swirl has a significant impact on the local blade loading of the first stage, which induces the mass flux nonuniformity as well as total pressure and total temperature distortion. The combined total pressure and total temperature distortion is significantly attenuated near tip and slightly enhanced near hub as it moves through the second stage. | GUO Jin HU Jun WANG Xuegao TU Baofeng | 2021 | Journal of Thermal Science2021，30，4： | 1 |
| 13 | Mettl3 deficiency leads to the upregulation of Cav1.2 and increases arrhythmia susceptibility in mice显示文摘Methyltransferase-like 3(Mettl3)is a component of methyltransferase complex that mediates m6A modification of RNAs,and participates in multiple biological processes.However,the role of Mettl3 in cardiac electrophysiology remains unknown.This study aims to explore the ventricular arrhythmia susceptibility of Mettl3+/–mice and the underlying mechanisms.Mice were anesthetized with 2%avertin(0.1 mL/10 g body weight)for echocardiography and programmed electrical pacing.Whole-cell patch clamp technique was used to examine the electrophysiological property of cardiomyocytes.The expression of Cav1.2 was determined by qRT-PCR and western blot analysis.The m6A medication of mRNA was examined by MeRIP-Seq and MeRIP-qPCR.No differences are found in the morphology and function of the hearts between Mettl3+/–mice and wild-type(WT)controls.The QT and QTc intervals of Mettl3+/–mice are significantly longer.High-frequency electrical stimulation showed that heterozygous knockout of Mettl3 increases ventricular arrhythmia susceptibility.The whole-cell patch-clamp recordings showed that the APD is prolonged in Mettl3+/–ventricular myocytes and more EADs were observed.The density of ICa-L is substantially increased in ventricular myocytes of Mettl3+/–mice.The pore-forming subunit of L-type calcium channel Cav1.2 is upregulated in Mettl3+/–mice,while the mRNA of its coding gene CACNA1C does not change.MeRIP-Seq and MeRIP-qPCR showed that the m6A methylation of CACNA1C mRNA is decreased in cultured Mettl3-knockdown cardiomyocytes and Mettl3+/–hearts.Collectively,deficiency of Mettl3 increases ventricular arrhythmia susceptibility due to the upregulation of Cav1.2 by reducing m6A modification on CACNA1C mRNA in mice.This study highlights the role of m6A modification in the regulation of cardiac electrophysiology. | Ling Shi Xuexin Jin Zheng Li Rui Gong Yang Guo Jiudong Ma Yang Zhang Benzhi Cai Baofeng Yang Dongmei Gong Zhenwei Pan | 2022 | Acta Biochimica et Biophysica Sinica2022，54，2： | 1 |
| 14 | Effects of RNAi-mediated gene silencing of LRIG3 expression on cell cycle and survival of glioma cells显示文摘 | Mingjun Cai Ruifan Xie Lin Han Rudong Chen Baofeng Wang Fei Ye Dongsheng Guo Ting Lei | 2009 | Journal of Huazhong University of Science and Technology2009，，1： | 1 |
| 15 | Human face recognition based on spatially weighted Hausdorff distance显示文摘 | Guo Baofeng Lam Kin-Man Lin Kwan-Ho | 2003 | Pattern Recognition Letters2003，24，13： | 1 |
| 16 | Gait feature subset by mutual information 显示文摘 | Guo Baofeng Mark S N | 2009 | IEEE Trans on Systens Man and Cybernetics-Part A: Systems and Humans2009，39，1： | 1 |
| 17 | Photoelectrocatalytic oxidation of Cu- 11 -EDTA at TiO2 electrode and simultaneous reco- very ofCu- by electrodeposition 显示文摘 | Zhao Xu Guo Libao Zhang Baofeng | 2013 | Environmental Science and Technology2013，47，9： | 1 |
| 18 | Transplanted iPSC-derived neural stem cells for spinal cord injury显示文摘Spinal cord injury(SCI),one of the most devastating central nervous system(CNS)disorders,can lead to severe neurological disabilities,the most severe forms of which include persistent paraplegia or quadriplegia.The efficacy of induced pluripotent stem cell(iPSC)derived neural stem cells(NSC)transplantation on functional recovery following acute spinal cord injury(SCI)was detected.NSC derived from iPSC was characterized by expression of specific markers(SOX2,nestin and PAX6). | Kong Desheng Feng Baofeng Guo Ruigyun Ernest Asiamah He Jingjing Zhang Shuhan Lyu Fei Liu Xin Ma Jun Huixian Cui | 2021 | 解剖学杂志2021，44，S01： | 0 |
| 19 | Novel Chemical Strategy for the Synthesis of RGDCySS Tetrapeptide显示文摘 | XU Baofeng YANG Sen ZHU Jinming MA Yudan ZHAO Gang GUO Yi XU Li | 2014 | Chemical Research in Chinese Universities2014，30，1： | 0 |
| 20 | Fragmentation of brain apolipoprotein E(ApoE)and its relevance in late onset Alzheimer's disease显示文摘Late-onset Alzheimer's disease(LOAD)is the most common cause of dementia in the elderly.Polymorphism in apolipoprotein E(ApoE)gene(ε2,ε3,and ε4)is the greatest LOAD risk factor.The translation products are ApoE2,ApoE3,and ApoE4,respectively.ApoE fragments are present in senile plaques and neurofibillary tangles but their contributions to AD pathogenesis are not clear. | Ernest Asiamah Jingjing He Ruiyun Guo Baofeng Feng Desheng Kong Xin Liu Jun Ma Huixian Cui | 2021 | 解剖学杂志2021，44，S01： | 0 |
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