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| 1 | The Genome of Artemisia annua Provides Insight into the Evolution of Asteraceae Family and Artemisinin Biosynthesis显示文摘Artemisia annua,通常已知的同样香甜的苦恼或 Qinghao,是到中国的一个灌木土著人并且长被用于药用的目的。A。annua 现在作为有势力抗疟药混合物的唯一的生来的来源全球性被栽培, artemisinin。这里,我们报导 A 的 1.74-gigabase 染色体的一个高质量的草稿集会。annua,高度异质接合,富于重复定序,并且包含 63 ? 226 编码蛋白质的基因,在定序的植物种类之中的最大的数字之一。我们发现了那,作为在 Asteraceae 的一些定序的染色体之一, A。annua 染色体包含对这大被子植物 clade 特定的很多基因。尤其是,扩大和编码涉及萜烯生合成的酶的基因的功能的多样化与 artemisinin biosynthetic 小径的进化一致。我们进一步由介绍那 A 的 transcriptome 揭示了。annua 发展了复杂 transcriptional 规章的网络位于 \O 下面 artemisinin 生合成。把转基因的 A 基于我们产生了的全面 genomic 和 transcriptomic 分析。artemisinin 高级的生产的 annua 线,它现在为大规模生产准备好了并且将从而帮助遇见增加 artemisinin 的全球需求的挑战。 | Qian Shen Lida Zhang Zhihua Liao Shengyue Wang Tingxiang Yan Pu Shi Meng Liu Xueqing Fu Qifang Pan Yuliang Wang Zongyou Lv Xu Lu Fangyuan Zhang Weimin Jiang Yanan Ma Minghui Chen Xiaolong Hao Ling Li Yueli Tang Gang Lv Yan Zhou Xiaofen Sun Peter E. Brodelius Jocelyn K.C. Rose Kexuan Tang | 2018 | Molecular Plant2018,11,6: | 47 |
| 2 | Laser cleaning of steel structure surface for paint removal and repaint adhesion显示文摘Paint removal from steel structure is executed for shipyards of marine and offshore engineering.Due to environmental unfriendliness and unhealthy drawbacks of sand blasting technique, laser ablation technique is proposed as a substituting method.By absorbing high energy of the 1064 nm pulsed laser, the paint is vaporized quickly.The ablated debris is then collected by using a suction pump.Initial metal surface of the steel is exposed when laser beam irradiates perpendicularly and scans over it.The cleaned surface fulfills the requirements of surface preparation standards ISO 8501 of SA2.The adhesion is further characterized with pull-off test after carrying out painting with Jotamastic 87 aluminum paint.The repainting can be embedded onto the laser cleaned surface to bond much more tightly.The excellent adhesion strength of 20 MPa between repainted coating and the substrate is achieved, which is higher than what is required by shipyards applications. | Xiaoguang Li Tingting Huang Ang Wei Chong Rui Zhou Yoo Sang Choo Minghui Hong | 2017 | 光电工程2017,44,3: | 24 |
| 3 | Exosomes containing miR-21 transfer the characteristic of cisplatin resistance by targeting PTEN and PDCD4 in oral squamous cell carcinoma显示文摘 | Tao Liu Gang Chen Dawei Sun Minghui Lei Yongqiang Li Changming Zhou Xiaodong Li Wei Xue Hong Wang Chunjun Liu Jiang Xu | 2017 | Acta Biochimica et Biophysica Sinica2017,49,9: | 22 |
| 4 | miR-181b functions as an oncomiR in colorectal cancer by targeting PDCDZ显示文摘 | Yanqing Liu Uzair-ur-Rehman Yu Guo Hongwei Liang Rongjie Cheng Fei Yang Yeting Hong Chihao Zhao Minghui Liu Mengchao Yu Xinyan Zhou Kai Yin Jiangning Chen Junfeng Zhang Chen-Yu Zhang Feng Zhi Xi Chen | 2016 | Protein & Cell2016,7,10: | 14 |
| 5 | SIDT1-dependent absorption in the stomach mediates host uptake of dietary and orally administered microRNAs显示文摘Dietary microRNAs have been shown to be absorbed by mammals and regulate host gene expression,but the absorption mechanism remains unknown.Here,we show that SIDT1 expressed on gastric pit cells in the stomach is required for the absorption of dietary microRNAs.SIDT1-deficient mice show reduced basal levels and impaired dynamic absorption of dietary microRNAs.Notably,we identified the stomach as the primary site for dietary microRNA absorption,which is dramatically attenuated in the stomachs of SIDT1-deficient mice.Mechanistic analyses revealed that the uptake of exogenous microRNAs by gastric pit cells is SIDT1 and low-pH dependent.Furthermore,oral administration of plant-derived miR2911 retards liver fibrosis,and this protective effect was abolished in SIDT1-deficient mice.Our findings reveal a major mechanism underlying the absorption of dietary microRNAs,uncover an unexpected role of the stomach and shed light on developing small RNA therapeutics by oral delivery. | Qun Chen Fan Zhang Lei Dong Huimin Wu Jie Xu Hanqin Li Jin Wang Zhen Zhou Chunyan Liu Yanbo Wang Yuyan Liu Liangsheng Lu Chen Wang Minghui Liu Xi Chen Cheng Wang Chunni Zhang Dangsheng Li Ke Zen Fangyu Wang Qipeng Zhang Chen-Yu Zhang | 2021 | Cell Research2021,31,3: | 10 |
| 6 | A review of oxygen reduction mechanisms for metal-free carbon-based electrocatalysts显示文摘The sluggish kinetics of Oxygen Reduction Reaction(ORR)at the cathode in proton exchange membrane fuel cells or metal-air batteries requires highly effective and stable electrocatalysts to boost the reaction.The low abundance and high price of Pt-based electrocatalysts hamper the widespread application of proton exchange membrane fuel cells and metal-air batteries.As promising alternatives,metal-free carbon materials,especially upon doping heteroatoms or creating defects demonstrated excellent ORR activity,which is as efficient as or even superior to commercial platinum on carbon.Significant progress on the development of advanced carbon materials as highly stable and durable catalysts has been achieved,but the catalytic mechanisms of these materials still remain undistinguished.In present review,we summarized the up-to-date progress in the studies of carbon materials,and emphasized on the combination of experiment and theory to clarify the underlying mechanisms of these materials.At last,we proposed the perspectives on the proper strategies of elucidating the mechanisms of carbon materials as electrocatalysts towards ORR. | Ruguang Ma Gaoxin Lin Yao Zhou Qian Liu Tao Zhang Guangcun Shan Minghui Yang Jiacheng Wang | 2019 | npj Computational Materials2019,,1: | 9 |
| 7 | Population Genomic Analysis and De Novo Assembly Reveal the Origin of Weedy Rice as an Evolutionary Game显示文摘Crop weediness,especially that of weedy rice(Oryza sativa f.spontanea),remains mysterious.Weedy rice possesses robust ecological adaptability;however,how this strain originated and gradually formed proprietary genetic features remains unclear?Here,we demonstrate that weedy rice at Asian high latitudes(WRAH)is phylogenetically well defined and possesses unselected genomic characteristics in many divergence regions between weedy and cultivated rice.We also identified novel quantitative trait loci underlying weedy-specific traits,and revealed that a genome block on the end of chromosome 1 is associated with rice weediness.To identify the genomic modifications underlying weedy rice evolution,we generated the first de novo assembly of a high-quality weedy rice genome(WR04-6),and conducted a comparative genomics study between WR04-6 with other rice reference genomes.Multiple lines of evidence,including the results of demographic scenario comparisons,suggest that differentiation between weedy rice and cultivated rice was initiated by genetic improvement of cultivated rice and that the essence of weediness arose through semi-domestication.A plant height model further implied that the origin of WRAH can be modeled as an evolutionary game and indicated that strategy-based selection driven by fitness shaped its genomic diversity. | Jian Sun Dianrong Ma Liang Tang Minghui Zhao Guangchen Zhangh Wenjia Wang Jiayu Song Xiang Li Zimeng Liu Wenxing Zhang Quan Xu Yuncheng Zhou Jianzhong Wu Toshio Yamamoto Fei Dai Yan Lei Song Li Gang Zhou Hongkun Zheng Zhengjin Xu Wenfu Chen | 2019 | Molecular Plant2019,12,5: | 9 |
| 8 | Simultaneous regulation of cations and anions in an electrolyte for high-capacity, high-stability aqueous zinc–vanadium batteries显示文摘Safe,inexpensive aqueous zinc-ion batteries(AZIBs)are regarded as promising energy storage devices.However,they still face issues,including dissolution and collapse of the cathode as well as H_(2)evolution and the growth of Zn dendrites on the Zn anode.Herein,we simultaneously regulate the cations and anions in the electrolyte for high-capacity,high-stability aqueous zinc–vanadium(Zn–V)batteries based on a bimetallic cation-doped Na_(0.33)K_(0.1)V_(2)O_(5)·nH_(2)O cathode.We demonstrate that Na^(+) cations suppress cathode dissolution and restrain Zn dendrite growth on the anode via an electrostatic shield effect.We also illustrate that ClO_(4)^(-) anions participate in energy storage at the cathode and are reduced to Cl^(-),generating a protective layer on the Zn anode surface and providing a stable interface to decrease Zn dendrites and H_(2)evolution during long-term cycling.When Na^(+) and ClO_(4)^(-) are introduced into an aqueous ZnSO_(4) electrolyte,a Zn/Zn symmetric cell shows durable and reversible Zn stripping/plating for 1500 h at a current density of 1 mA cm^(-2) and with an area capacity of 1 mAh cm^(-2).Zn/Na_(0.33)K_(0.1)V_(2)O_(5)·nH_(2)O full batteries exhibit a high capacity of 600 mAh g^(-1)at 0.1 A g^(-1) and long-term cycling performance for 5000 cycles,with a capacity of 200 mAh g^(-1) at 20 Ag^(-1). | Ziqing Wang Miao Zhou Liping Qin Minghui Chen Zixian Chen Shan Guo Liangbing Wang Guozhao Fang Shuquan Liang | 2022 | eScience2022,2,2: | 8 |
| 9 | Mett13-Mettl14 methyltransferase complex regulates the quiescence of adult hematopoietic stem cells显示文摘 | QiJason Yao Lina Sang Minghui Lin Xiujuan Yin Wenjie Dong Yuping Gong Bo O. Zhou | 2018 | Cell Research2018,28,9: | 8 |
| 10 | Structural Evolution and Hydrocarbon Potential of the Upper Paleozoic Northern Ordos Basin, North China显示文摘在北 Ordos 盆的 Hangjinqi 区域的烃潜力不是众所周知的,与盆的另外的区域相比,尽管有它的实质的石油系统。越过在东方 Hangjinqi 区域的 Hangjinqi 差错地区( HFZ )的变换深度的地震侧面的恢复显示出创造了背斜的结构在的一压缩晚三叠纪,并且在 ∼Middle 侏罗记的二延期和晚早的白垩纪,它被倒置分别地在晚侏罗记早的早白垩纪和迟了的白垩纪打断。在在中央 Ordos 盆(圆块) 的井地点的烃产生开始了在晚三叠纪。盆当模特儿井 Zhao-4 从北 Shanbei 斜坡的迟了的含碳早二叠的煤措施建议那烃代在早白垩纪达到顶点,在迟了的白垩纪早于倒置。在 Shanbei 斜坡的大多数来源岩石除了 Hangjinqi 区域来源岩石(井 Jin-48 ) 传递了主要煤气迁居的阶段。因为盆充满阶层向南正在蘸,从 COB 产生的烃是可能的沿着 HFZ 向背斜的结构和陷井向北方移植了。指责在 Hangjinqi 区域的 extensional 阶段(晚早的白垩纪) 期间继续那可能为烃的迁居充当了水管。因此,到 HFZ 的北方的背斜的结构和联系陷井可能套住自从中间的侏罗记,在 COB 从迟了的含碳早二叠的煤措施被控告的烃。 | YANG Minghui LI Liang ZHOU Jin JIA Huichong SUN Xiao GONG Ting DING Chao | 2015 | Acta Geologica Sinica(English Edition)2015,89,5: | 7 |
| 11 | Hybrid metal-insulator-metal structures on Si nanowires array for surface enhanced Raman scattering显示文摘Surface enhanced Raman scattering(SERS)is an efficient technique to detect low concentration molecules.In this work,periodical silicon nanowires(Si NWs)integrated with metal-insulator-metal(MIM)layers are employed as SERS substrates.Laser interference lithography(LIL)combined with reactive ion etching(RIE)is used to fabricate large-area periodic nanostructures,followed by decorating the MIM layers.Compared to MIM disks array on Si surface,the SERS enhancement factor(EF)of the MIM structures on the Si NWs array can be increased up to 5 times,which is attributed to the enhanced electric field at the boundary of the MIM disks.Furthermore,high density of nanoparticles and nanogaps serving as hot spots on sidewall surfaces also contribute to the enhanced SERS signals.Via changing the thickness of the insulator layer,the plasmonic resonance can be tuned,which provides a new localized surface plasmon resonance(LSPR)characteristic for SERS applications. | Kaichen Xu Chentao Zhang Tzu Hsiao Lu Puqun Wang Rui Zhou Rong Ji Minghui Hong | 2017 | 光电工程2017,44,2: | 6 |
| 12 | Synthesis of Z-scheme g-C3N4 nanosheets/Ag3PO4 photocatalysts with enhanced visible-light photocatalytic performance for the degradation of tetracycline and dye显示文摘Graphene-like C3N4/Ag3PO4 photocatalysts are synthesized by calcination and solutions precipitating method.The obtained g-C3N4/Ag3PO4 composites display excellent photocatalytic activity for the degradation of methylene orange(MO),rhodamine B(RhB)and tetracycline(TC)under visible light irradiation.The solutions containing RhB(10 mg/L)and MO(10 mg/L)can be efficiently degraded within15 min and 30 min.Especially,nearly 80%of TC(50 mg/L)is degraded within 20 min.which are much better than those of pure g-C3N4 nanosheets and Ag3PO4,implying that strong interaction and reasonable energy band alignment in the contact interface can effectively transfer the carries.Furthermore,the g-C3N4/Ag3PO4 composites exhibit the improved stability,and only a slight decrease is observed after three recycling runs.Moreover,the impact of inorganic ions and PH values on the degradation performance is rather small.The Z-scheme photocatalytic mechanism of the g-C3N4/Ag3PO4 composites based on the active species trapping experimental is proposed.This work demonstrates the promising applications of the g-C3N4/Ag3PO4 composites in environmental issues. | Meng Ding Juanjuan Zhou Hongcen Yang Ruya Cao Shouwei Zhang Minghui Shao Xijin Xu | 2020 | Chinese Chemical Letters2020,31,1: | 6 |
| 13 | Development and validation of an analytical method for detecting chlorantraniliprole residues in fresh tea leaves显示文摘An efficient method using multiwalled carbon nanotubes(MWCNTs)as dispersive solid-phase extraction sorbent was established for determining chlorantraniliprole residues in fresh tea leaves,which are known to be a troublesome matrix containing abundant pigments,via gas chromatography with an electron capture detector.Acetonitrile was used as the extraction solvent,with sodium chloride enhancing the analyte partition in the organic phase.The optimal mixture of MWCNTs and primary secondary amine(PSA)was based on the distribution of the target analyte recovery and on the clean-up efficiency;while matrix-matched calibration was recommended to combat the matrix effect.Mean recoveries of 95.2%–108.8%were obtained with intraday and interday precisions of less than 7.9%and 10.3%,respectively.Good linearity was observed for concentrations of 0.02–1.0 mg/kg with a correlation coefficient of 0.9984.The limits of detection and quantification were 0.005 mg/kg and 0.02 mg/kg,respectively.The method was employed to investigate the dissipation dynamics of chlorantraniliprole in fresh tea leaves with real field samples.Consequently,the dissipation rates of chlorantraniliprole in fresh tea leaves followed pseudo-first-order kinetics with a half-life of 1.9 d,and the average chlorantraniliprole residue content was below 0.02 mg/kg with a harvest withholding period of 14 d. | Tengfei Liu Minghui Dong Fengjie Zhou Daifeng Yang Xueming Zhang | 2019 | Food Science and Human Wellness2019,8,4: | 5 |
| 14 | Remote-mode microsphere nano-imaging:new boundaries for optical microscopes显示文摘Optical microscope is one of the most popular characterization techniques for general purposes in many fields. It is distinguishedfrom the vacuum or tip-based imaging techniques for its flexibility, low cost, and fast speed. However, its resolutionlimits the functionality of current optical imaging performance. While microspheres have been demonstrated forimproving the observation power of optical microscope, they are directly deposited on the sample surface and thus theapplications are greatly limited. We develop a remote-mode microsphere nano-imaging platform which can scan freelyand in real-time across the sample surfaces. It greatly increases the observation power and successfully characterizesvarious practical samples with the smallest feature size down to 23 nm. This method offers many unique advantages,such as enabling the detection to be non-invasive, dynamic, real-time, and label-free, as well as leading to more functionalitiesin ambient air and liquid environments, which extends the nano-scale observation power to a broad scope inour life. | Lianwei Chen Yan Zhou Mengxue Wu Minghui Hong | 2018 | Opto-Electronic Advances2018,1,1: | 4 |
| 15 | Wide bandwidth acoustic transmission via coiled-up metamaterial with impedance matching layers显示文摘Many acoustic metamaterials suffer from a narrow bandwidth transmission because of the impedance mismatch at the airmetamaterial interface. In this paper, a two-dimensional impedance-matched metamaterial with broadband transmission performance is investigated. The impedance matching layer is introduced for a gradient variation of effective impedance from the inlet of the unit to the outlet. The effective medium theory and corresponding effective model are used to explain the underlying mechanism. The improved energy transmission of our designs is demonstrated by experiment and numerical simulation within a broad frequency bandwidth over 6 kHz. Our impedance-matched design can be used to enhance sound absorption, which is expected to present improved acoustic performance in the applications of acoustic damper and muffler. | Xiao Jia Yang Li Yinghao Zhou Minghui Hong Ming Yan | 2019 | Science China(Physics,Mechanics & Astronomy)2019,62,6: | 3 |
| 16 | An in-situ formed ceramic/alloy/ceramic sandwich barrier to resist elements interdiffusion between NiCrAlY coating and a Ni-based superalloy显示文摘NiCrAlY coatings are widely applied on various alloy components to enhance oxidation and/or corrosion resistance at high temperatures.However,elements interdiffusion occurs between them due to composition difference.Although various diffusion barriers(DBs)are reported,this problem is still far from completely solved as most ceramic barriers suffer from poor adherence,while the metallic barriers play a limited role.In this study,NiCrAlY coating was deposited onto a second-generation single-crystal superalloy by arc ion plating.A novel simple method is provided to address elements interdiffusion.By pre-oxidation at a moderate temperature,a thin scale of Ni(Co)O forms at the alloy surface.It transforms to be an alumina/NiCoCr alloy/alumina sandwich by an in-situ reaction with the overlaying NiCrAlY coating and the alloy substrate at high service temperatures,which offers good barrier ability in conjunction with strong adhesion.In the presence of such an alumina/alloy/alumina DB,the NiCrAlY coating provides high resistance to oxidation and scale spallation for the alloy substrate. | Cean Guo Feng Zhou Minghui Chen Jinlong Wang Shenglong Zhu Fuhui Wang | 2021 | Journal of Materials Science & Technology2021,,11: | 3 |
| 17 | Enhancement of laser ablation via interacting spatial double‐pulse effect显示文摘 | Rui Zhou Shengdong Lin Ye Ding Huan Yang Kenny Ong Yong Keng Minghui Hong | 2018 | Opto-Electronic Advances2018,1,8: | 3 |
| 18 | Numerical Simulation of Dam-Break Flooding of Cascade Reservoirs显示文摘Previous studies at home and abroad have mainly focused on single dam-break, and little attention has been paid so far to the dam-break of cascade reservoirs.Multi-source flooding, which can lead to three-dimensional turbulent phenomena and superposition effects, is the main difference between the dam-break of cascade and single reservoirs. Detailed descriptions of the coupled numerical simulation of multi-source flooding have little been reported, and the initial wet riverbed is rarely considered in current models. Therefore, in this paper, a method based on the three-dimensional k-ε turbulence model coupled with the volume-of-fluid method is proposed to simulate the dam-break flooding of cascade reservoirs. The upstream river, reservoir, and downstream river are connected by the internal boundary method, and the initial conditions,including river flow and reservoir water, are determined according to the results of the numerical simulation. Coupled numerical simulation of different dam-break flooding is then achieved. The present work solves the challenges presented by the enhancement and superposition of natural river flow, upstream flooding, and downstream flooding.This paper provides a theoretical basis for future studies on the dam-break flood routing of cascade reservoirs. | Zhengyin Zhou Xiaoling Wang Wenlong Chen Shaohui Deng Minghui Liu | 2017 | Transactions of Tianjin University2017,23,6: | 3 |
| 19 | Variable Parameter Nonlinear Control for Maximum Power Point Tracking Considering Mitigation of Drive-train Load显示文摘Since mechanical loads exert a significant influence on the life span of wind turbines, the reduction of transient load on drive-train shaft has received more attention when implementing a maximum power point tracking(MPPT) controller.Moreover, a trade-off between the efficiency of wind energy extraction and the load level of drive-train shaft becomes a key issue. However, for the existing control strategies based on nonlinear model of wind turbines, the MPPT efficiencies are improved at the cost of the intensive fluctuation of generator torque and significant increase of transient load on drive train shaft. Hence, in this paper, a nonlinear controller with variable parameter is proposed for improving MPPT efficiency and mitigating transient load on drive-train simultaneously. Then,simulations on FAST(Fatigue, Aerodynamics, Structures, and Turbulence) code and experiments on the wind turbine simulator(WTS) based test bench are presented to verify the efficiency improvement of the proposed control strategy with less cost of drive-train load. | Zaiyu Chen Minghui Yin Lianjun Zhou Yaping Xia Jiankun Liu Yun Zou | 2017 | IEEE/CAA Journal of Automatica Sinica2017,4,2: | 2 |
| 20 | First principles study of CuAlO_2 doping with S显示文摘We study the electronic properties of CuAlO2 doped with S by the first principles calculations and find that the band gap of CuAlO2 is reduced after the doping.At the same time,the effective masses are also reduced and the density of states could cross the Fermi level.These results show that the conductivity of CuAlO2 could be enhanced by doping the impurities of S,which needs to be further studied. | GAO HaiGen 1,ZHOU Jian 1,2* & LU MingHui 1 1 National Laboratory of Solid State Microstructures and Department of Materials Science and Engineering,Nanjing University,Nanjing 210093,China 2 Group of Computational Condensed Matter Physics,National Laboratory of Solid State Microstructures and Department of Physics,Nanjing University,Nanjing 210093,China | 2010 | Science China(Physics,Mechanics & Astronomy)2010,53,7: | 2 |