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| 1 | Optimal Operation of Integrated Energy Systems Subject to Coupled Demand Constraints of Electricity and Natural Gas显示文摘This paper proposes a hybrid multi-objective optimization and game-theoretic approach(HMOGTA)to achieve the optimal operation of integrated energy systems(IESs)consisting of electricity and natural gas(E&G)utility networks,multiple distributed energy stations(DESs),and multiple energy users(EUs).The HMOGTA aims to solve the coordinated operation strategy of the electricity and natural gas networks considering the demand characteristics of DESs and EUs.In the HMOGTA,a hierarchical Stackelberg game model is developed for generating equilibrium strategies of DESs and EUs in each district energy network(DEN).Based on the game results,we obtain the coupling demand constraints of electricity and natural gas(CDCENs)which reflect the relationship between the amounts and prices of electricity and cooling(E&C)that DESs purchase from utility networks.Furthermore,the minimization of conflicting costs of E&G networks considering the CDCENs are solved by a multi-objective optimization method.A case study is conducted on a test IES composed of a 20-node natural gas network,a modified IEEE 30-bus system,and 3 DENs,which verifies the effectiveness of the proposed HMOGTA to realize fair treatment for all participants in the IES. | Yingjie Qin Lilan Wu Jiehui Zheng Mengshi Li Zhaoxia Jing Q.H.Wu Xiaoxin Zhou Feng Wei | 2020 | CSEE Journal of Power and Energy Systems2020，6，2： | 7 |
| 2 | Knockdown of c-Myc inhibits cell proliferation by negatively regulating the Cdk/Rb/E2F pathway in nasopharyngeal carcinoma cells显示文摘proto-oncogene c-Myc 编码涉及细胞的增长,区别,和 apoptosis 的规定的一个抄写因素。几研究显示 c-Myc 的在表示上是在鼻咽的癌(NPC ) 的经常的基因畸形。因此,明确地在确定的 NPC 房间线由基因工具减少它的水平帮助更好在 NPC 的致病理解它的角色。在这研究,第一次,我们成功地由采用一条基于 DNA 的 RNA 干扰途径与稳定地压制的 c-Myc 表示建立了并且描绘 NPC 5-8F 房间线。c-Myc 的抑制在 5-8F 房间导致了减少的房间生长,殖民地形成,和房间周期前进。在 vivo 肿瘤,形成试金表明减少的 c-Myc 击倒在裸体老鼠的 5-8F 房间的 tumorigenic 潜力。在分子的水平,我们发现 c-Myc 击倒能减少涉及 Cdk/Rb/E2F 小径,包括的 CDK4, cyclin D1, CDK2, pRb, E2F3,和 DP2,并且显著地减少了 cyclin D1 的倡导者活动的几个批评分子的表示。一起拿,这些调查结果在鼻咽的 carcinogenesis 提供珍贵机械学的卓见进 c-Myc 的角色并且建议 c-Myc 击倒可以是为 NPC 的处理的一条潜在的治疗学的途径。 | Zhaoxia Niu Huaying Liu Ming Zhou Heran Wang Yukun Liu Xiayu Li Wei Xiong Jian Ma Xiaoling Li Guiyuan Li | 2015 | Acta Biochimica et Biophysica Sinica2015，47，3： | 5 |
| 3 | Drug-loaded balloon with built-in NIR controlled tip-separable microneedles for long-effective arteriosclerosis treatment显示文摘Drug-eluting balloon(DEB)angioplasty has emerged as an effective treatment for cardiovascular and cerebrovascular diseases.However,distal embolism and late lumen restenosis could be caused by drug loss during DEB handling and rapid drug metabolization.Here,a drug-loaded balloon equipped with tip-separable microneedles on the balloon surface(MNDLB)was developed.Inbuilt near-infrared(NIR)ring laser inside the catheter inner shaft was introduced to activate the biodegradable microneedle tips for the first time.The drug-loaded tips thus could be embedded in the vasculature and then released antiproliferative drug-paclitaxel slowly via polymer degradation for more than half a year.A significant increase in drug delivery efficiency and superior therapeutic effectiveness compared with the standard DEB were demonstrated using an atherosclerosis rabbit model. | Li Huang Huaqiang Fang Teng Zhang Binbin Hu Shichen Liu Fanzhen Lv Zhaoxia Zeng Huijie Liu Weimin Zhou Xiaolei Wang | 2023 | Bioactive Materials2023，，5： | 2 |
| 4 | Deep-red emitting Mg2Ti04:Mn^(4+)phosphor ceramics for plant lighting显示文摘In this study,deep-red emitting Mg2T i04:Mn4 phosphor ceramics were synthesized by the high temperature solid-state reaction method.The ceramics can be excited by the 465 nm blue light and had a narrow emission with a full width at half maximum(FWMH)value of 31 nm.The peak wavelength was located at 658 nm,which matched the demanded wavelength for photosynthesis.The crystal field strength(Dq)and the Racah parameters(B and C)were estimated by the Tanabe-Sugano diagram.The thermal conductivity of the Mg2Ti(0.999)O4:0.001Mn^(4+)ceramic was 7.535 W/(m·K)at room temperature,which was one order of magnitude higher than that of the traditional packaging method using the silicone gel.A set of phosphor converted LEDs were fabricated by mounting the phosphor ceramics onto the 460 nm blue LED chips and the CIE coordinates can move from the blue region to the purple light region with the thickness of the ceramic increasing.These results indicated that the Mg2Ti04:Mn^(4+)phosphor ceramic was suitable for plant lighting when combined with a blue LED chip. | Zixin WANG Hui LIN Dawei ZHANG Yiming SHEN Yang LI Ruijin HONG Chunxian TAO Zhaoxia HAN Lei CHEN Shengming ZHOU | 2021 | Journal of Advanced Ceramics2021，10，1： | 2 |
| 5 | The Msi1-mTOR pathway drives the pathogenesis of mammary and extramammary Paget’s disease显示文摘Mammary and extramammary Paget’s Diseases(PD)are a malignant skin cancer characterized by the appearance of Paget cells.Although easily diagnosed,its pathogenesis remains unknown.Here,single-cell RNA-sequencing identified distinct cellular states,novel biomarkers,and signaling pathways—including mTOR,associated with extramammary PD.Interestingly,we identified MSI1 ectopic overexpression in basal epithelial cells of human PD skin,and show that Msi1 overexpression in the epidermal basal layer of mice phenocopies human PD at histopathological,single-cell and molecular levels.Using this mouse model,we identified novel biomarkers of Paget-like cells that translated to human Paget cells.Furthermore,single-cell trajectory,RNA velocity and lineage-tracing analyses revealed a putative keratinocyte-to-Paget-like cell conversion,supporting the in situ transformation theory of disease pathogenesis.Mechanistically,the Msi1-mTOR pathway drives keratinocyte-Paget-like cell conversion,and suppression of mTOR signaling with Rapamycin significantly rescued the Paget-like phenotype in Msi1-overexpressing transgenic mice.Topical Rapamycin treatment improved extramammary PD-associated symptoms in humans,suggesting mTOR inhibition as a novel therapeutic treatment in PD. | Yongli Song Christian F.Guerrero-Juarez Zhongjian Chen Yichen Tang Xianghui Ma Cong Lv Xueyun Bi Min Deng Lina Bu Yuhua Tian Ruiqi Liu Ran Zhao Jiuzhi Xu Xiaole Sheng Sujuan Du Yeqiang Liu Yunlu Zhu Shi-jun Shan Hong-duo Chen Yiqiang Zhao Guangbiao Zhou Jianwei Shuai Fazheng Ren Lixiang Xue Zhaoxia Ying Xing Dai Christopher J.Lengner Bogi Andersen Maksim V.Plikus Qing Nie Zhengquan Yu-Show | 2020 | Cell Research2020，30，10： | 2 |
| 6 | Deformation Analysis and Fixture Design of Thin-walled Cylinder in Drilling Process Based on TRIZ Theory显示文摘Thin-walled cylindrical workpiece is easy to deform during machining and clamping processes due to the insufficient rigidi.Moreover,it’s also difficult to ensure the perpendicularity of flange holes during drilling process.In this paper,the element birth and death technique is used to obtain the axial deformation of the hole through finite element simulation.The measured value of the perpendicularity of the hole was compared with the simulated value to verify then the rationality of the simulation model.To reduce the perpendicularity error of the hole in the drilling process,the theory of inventive principle solution(TRIZ)was used to analyze the drilling process of thin-walled cylinder,and the corresponding fixture was developed to adjust the supporting surface height adaptively.Three different fixture supporting layout schemes were used for numerical simulation of drilling process,and the maximum,average and standard deviation of the axial deformation of the flange holes and their maximum hole perpendicularity errors were comparatively analyzed,and the optimal arrangement was optimized.The results show that the proposed deformation control strategy can effectively improve the drilling deformation of thin-walled cylindrical workpiece,thereby significantly improving the machining quality of the parts. | Fulin WANG Bo SHENG Yongwen WU Jiawang LI Zhou XU Zhaoxia ZHU | 2021 | Mechanical Engineering Science2021，3，1： | 1 |
| 7 | Investigation of indoor environmental quality in Shanghai metro stations, China显示文摘 | Xiaojiang Ye Zhiwei Lian Chunxiao Jiang Zhaoxia Zhou Huanxin Chen | 2010 | Environmental Monitoring and Assessment (-)2010，，1： | 1 |
| 8 | Comparison and Error Analysis of Off-design and Design Models of Energy Hubs显示文摘The accuracy of the simulation model has a pro-found impact on the optimal operation of the energy hubs(EHs).However,in many articles,the constant model of the efficiency of equipment is adopted to formulate the operation system,which would probably lead to a simplification of the simulation models.But,EHs are typically operated under off-design condition due to the fluctuations in cooling,heating,electricity requirement.More-over,even though the off-design characteristics are considered,few studies have suggested comparing the differences between those two models by considering the operation cost.In order to assess the effect of the off-design characteristics of EH on the optimal operation accuracy in this paper,two test cases are performed on the fixed and variable load conditions,respectively.In addition,the individual effect of off-design characteristics of each equipment on the optimal operation cost of the EH is also investigated through four optimization runs.It is worth mentioning that the optimal operation problem of the EH considering the off-design characteristics and on-off status of the equipment is a mixed integer non-linear programming problem(MINLP).By testing the design and off-design models on the two cases,the results of simulation demonstrate that the optimal operation cost for the off-design model is larger than that for the design model.Nonetheless,in the aspect of the authenticity of the system operation strategy,the off-design model performs better than the design model.Furthermore,a larger relative error of the system operation cost between the two models can be observed when the EH is operated under a relatively lower load condition,revealing that the influence of off-design characteristic on the optimal operation of EHs is too significant to be neglected. | J.H.Zheng Jun Huang Shan Deng Q.H.Wu Mengshi Li Xiaoxin Zhou Zhaoxia Jing | 2019 | CSEE Journal of Power and Energy Systems2019，5，4： | 1 |
| 9 | Differential roles of STAT3 in the initiation and growth of lung cancer显示文摘 | JINGJIAO ZHOU ZHAOXIA QU SHAPEI YAN | 2015 | Oncogene2015，34，29： | 1 |
| 10 | A novel aluminum-carbon nanotubes nanocomposite with doubled strength and preserved electrical conductivity显示文摘Enhancing the mechanical strength of highly conductive pure metals usually causes significant reduction in their electrical conductivity.For example,introducing phase/matrix interfaces or more grain boundaries,are common and effective methods to strengthen metals.But it simultaneously increases the electron scattering at the interface,thus reducing the electrical conductivity.In this study,we demonstrate that pure aluminum(Al)/carbon nanotubes(CNTs)nanocomposites prepared by friction stir processing have successfully broken through these limitations.The yield strength and tensile strength of Al/CNTs nanocomposites have improved by 104.7%and 51.8%compared to pure Al,while the electrical conductivity remained comparable to that of pure Al.To explore the potential mechanisms,the interface between CNTs and Al was examined and characterized by transmission electron microscopy(TEM)and Raman spectroscopy.Little interfacial reaction compounds were present and no visible physical gaps were observed at CNTs and Al interfaces.We defined it as a clean and tightly bonded interface.Although the quantity of phase interface has increased,the electrical conductivity of the nanocomposite remains approximately unchanged.We attribute the preserved electrical conductivity to the clean and tightly bonded CNTs/Al interface in the nanocomposite. | Shuai Zhang Gaoqiang Chen Timing Qu Jinquan Wei Yufan Yan Qu Liu Mengran Zhou Gong Zhang Zhaoxia Zhou Huan Gao Dawei Yao Yuanwang Zhang Qingyu Shi Hua Zhang | 2021 | Nano Research2021，14，8： | 1 |
| 11 | Multi-scale numerical analysis on dynamic response and local damage in long-span bridges 显示文摘 | Li Zhaoxia Zhou Taiquan Chan T H T Yu Yang | 2007 | Engineering Structures2007，29，： | 1 |
| 12 | Water transport and water use efficiency differ among Populus euphratica Oliv. saplings exposed to saline water irrigation显示文摘Populus euphratica Oliv.is a unique woody tree that can be utilized for vegetation restoration in arid and semi-arid areas.The effects of saline water irrigation(0.00, 2.93, 8.78 and 17.55 g/L NaCl solutions) on water transport and water use efficiency(WUE) of P.euphratica saplings were researched for improving the survival of P.euphratica saplings and vegetation restoration in arid and semi-arid areas of Xinjiang, China in 2011.Results showed that hydraulic conductivity and vulnerability to cavitation of P.euphratica saplings were more sensitive in root xylem than in twig xylem when irrigation water salinity increased.Irrigation with saline water concentration less than 8.78 g/L did not affect the growth of P.euphratica saplings, under which they maintained normal water transport in twig xylem through adjustment of anatomical structure of vessels and kept higher WUE and photosynthesis in leaves through adjustment of stomata.However, irrigation with saline water concentration up to 17.55 g/L severely inhibited the photochemical process and WUE of P.euphratica saplings, resulting in severe water-deficit in leaves and a sharp reduction in water transport in xylem.Thus, it is feasible to irrigate P.euphratica forest by using saline groundwater for improving the survival of P.euphratica saplings and vegetation restoration in arid and semi-arid areas of Xinjiang, China. | ZHOU Honghua CHEN Yaning ZHU Chenggang YANG Yuhai YE Zhaoxia | 2019 | Journal of Arid Land2019，11，6： | 0 |
| 13 | Construction and properties of venlafaxine hydrochloride sustained release system based on hollow mesoporous silica microspheres显示文摘The aim of this work is to develop a venlafaxine hydrochloride sustained release system based on hollow mesoporous silica microspheres(HMSMs).HMSMs were innovatively prepared with tetraethyl silicate(TEOS)as the precursor and volatile n-heptane as a soft template.The obtained HMSMs show a well-defined hollow structure with an average size of 967 nm and pore volume of 0.85 cm^(3)/g,implying it is a potential drug carrier.Subsequently,venlafaxine hydrochloride(VF)was absorbed in the HMSMs with a content of 37.67% or so.The sustained release effect is further measured by the dissolution in-strument at 37℃ and 50 rpm in ultrapure water.The results showed that the HMSMs/VF system shows good sustained release properties compared with sustained release tablets with hydroxypropyl meth-ylcellulose as the main component.This HMSMs sustained release system appears to be a promising candidate for a sustained drug release. | Chenjing Liang Lingling Shi Zhengguo Chen Lan Zhou Zhaoxia Zhang Guoqing Zhang | 2024 | Particuology2024，86，3： | 0 |
| 14 | Spatiotemporal variations and determinants of stream nitrogen and phosphorus concentrations from a watershed in the Three Gorges Reservoir Area,China显示文摘Socioeconomic development induced nonpoint source(NPS)pollution has aroused an increasing concern,however,most of the previous studies were concentrated on the impacts of environmental determinants.Here,total nitrogen(TN)and total phosphorus(TP)concentrations from 13 sampling sites were collected biweekly from January 2018 to October 2021,and 26 potential factors including environmental and socioeconomic were considered in the Wangjiaqiao watershed of the Three Gorges Reservoir Area,China.Impacts of these factors on TN and TP were evaluated by partial least squares regression(PLSR)model.It showed that average TN and TP concentrations in wet seasons(TN,14.68 mg L^(-1):TP,0.113 mg L^(-1))were higher than that in dry seasons(TN,11.73 mg L^(-1);TP,0.087 mg L^(-1)).Additionally,the TN concentrations were greater in downstream than upstream,however,the highest TP concentrations were found in the middle of the watershed.The optimal PLSR model explained 69.6%,73.1%and 66.1%of the variance in TN concentration,as well as 65.7%,79.5%and 67.4%of the variance in TP concentration during the annual,dry and wet seasons,respectively.Moreover,TN was primarily influenced by topographic wetness index,planting structure,interspersion and juxtaposition index,orchard proportion,nitrogen fertilization,per capita income,and catchment area,whereas TP was mainly controlled by slope gradient,topographic wetness index,hypsometric integral,interspersion and juxtaposition index,and population density.Collectively,environmental factors had greater impacts on the TN and TP concentrations than socioeconomic factors.Raising farmers'awareness of the hazards of NPS pollution is beneficial to watershed NPS pollution control. | Jun Deng Yiwen Zhou Lin Chu Yujie Wei Zhaoxia Li Tianwei Wang Cuiting Dai | 2023 | International Soil and Water Conservation Research2023，11，3： | 0 |
| 15 | Comparative and population genomics of buckwheat species reveal key determinants of flavor and fertility显示文摘Common buckwheat(Fagopyrum esculentum)is an ancient crop with a world-wide distribution.Due to its excellent nutritional quality and high economic and ecological value,common buckwheat is becoming increasingly important throughout the world.The availability of a high-quality reference genome sequence and population genomic data will accelerate the breeding of common buckwheat,but the high heterozygosity due to the outcrossing nature has greatly hindered the genome assembly.Here we report the assembly of a chromosome-scale high-quality reference genome of F.esculentum var.homotropicum,a homozygous self-pollinating variant of common buckwheat.Comparative genomics revealed that two cultivated buckwheat species,common buckwheat(F.esculentum)and Tartary buckwheat(F.tataricum),underwent metabolomic divergence and ecotype differentiation.The expansion of several gene families in common buckwheat,including FhFAR genes,is associated with its wider distribution than Tartary buckwheat.Copy number variation of genes involved in the metabolism of flavonoids is associated with the difference of rutin content between common and Tartary buckwheat.Furthermore,we present a comprehensive atlas of genomic variation based on whole-genome resequencing of 572 accessions of common buckwheat.Population and evolutionary genomics reveal genetic variation associated with environmental adaptability and floral development between Chinese and non-Chinese cultivated groups.Genome-wide association analyses of multi-year agronomic traits with the content of flavonoids revealed that Fh05G014970 is a potential major regulator of flowering period,a key agronomic trait controlling the yield of outcrossing crops,and that Fh06G015130 is a crucial gene underlying flavor-associated flavonoids.Intriguingly,we found that the gene translocation and sequence variation of FhS-ELF3 contribute to the homomorphic self-compatibility of common buckwheat.Collectively,our results elucidate the genetic basis of speciation,ecological adaptation,fertility,and unique flavor of common buckwheat,and provide new resources for future genomics-assisted breeding of this economically important crop. | Kaixuan Zhang Yuqi He Xiang Lu Yaliang Shi Hui Zhao Xiaobo Li Jinlong Li Yang Liu Yinan Ouyang Yu Tang Xue Ren Xuemei Zhang Weifei Yang Zhaoxia Sun Chunhua Zhang Muriel Quinet Zlata Luthar Mateja Germ Ivan Kreft Dagmar Janovska Vladimir Meglic Barbara Pipan Milen I.Georgiev Bruno Studer Mark A.Chapman Meiliang Zhou | 2023 | Molecular Plant2023，16，9： | 0 |
| 16 | Occurrence Regularity of Major Damage Generations of Nilaparvata lugens(Stl) in Single Cropping Medium Rice Region in Sandu County of Guizhou Province显示文摘In order to clarify occurrence regularity of major damage generations of Nilaparvata lugens( Stl) in Sandu Shui Autonomous County( Sandu County for short),Guizhou Province,a karst single cropping medium rice region,the population dynamics of N. lugens were systematically studied using the methods of light trap and systematic field survey from 2009 to 2011. The results showed that the number of immigration generations caught by light trap and the actual population of N. lugens in fields were different among three years. The daily maximum trapping numbers of N. lugens amounted to 6 688 in 2009,which were 15. 3 and 2. 5 times of that in 2010 and 2011,respectively. The peak numbers in prediction nursery were 10 777,4 630 and 1 615 heads per hundred hills in 2009,2010 and 2011,respectively. The forth and fifth generations of N. lugens were the major damage generations in single cropping medium rice fields,and the initial immigration day was significantly related with primary-peak day. The occurrence degree of adults and nymphs of N. lugens varied with years and transplanting periods,and the peak days of N. lugens nymphs were from late July to early August in 2010 and 2011. The occurrence peaks of adults and nymphs in late transplanting paddy field were later than that in the early one. Meanwhile,the coexisted various growth periods of rice,due to time differences of transplanting,were conducive to inhabitation and reproduction of N. lugens. The population dynamics of spiders and Cyrtohinus lividipennis well synchronied with that of N. lugens,but predatory capacity of spiders and C. lividipennis was not enough to control N. lugens. | Liu Tianlei Jin Daochao Yang Hong Ai Zhengxian Zhou Zhaoxia | 2014 | Plant Diseases and Pests2014，5，2： | 0 |
| 17 | Analysis of the Curative Effect of Preoperative Intra-Arterial Infusion Chemoembolization on Stage IB2-IIB Uterine Cervix Cancer显示文摘OBJECTIVETo investigate the short-term and long-termtherapeutic efficacy of preoperative intra-arterial infusion chemo-embolization on stage IB_2-IIB uterine cervix cancer (UCC).METHODS A total of 143 patients with Stage IB_2-IIB UCCwere divided into a clinical trial group and a control group.Thepatients in the clinical trial group(n=86)were treated with acombined therapy,i.e.,preoperative intra-arterial infusion chemo-embolization,surgical therapy and postoperative radiotherapy,and those in the control group (n=57) were given surgical therapyand post-operative radiotherapy.The adverse effects,changes inlocal lesion and pathological examinations of the cancer,and thestate during the surgery were observed after the intra-arterialinfusion chemo-embolization.The survival rate and recurrencerate between the two groups were compared.RESULTS The total effective rate of the intra-arterial infusionchemo-embolization on Stage IB_2-IIB UCC was 93.02%.Thetreatment could reduce tumor size,bring about retro-conversionsof the clinical stage of the tumors and pathological grade of thecancer cells,and decrease the quantity of intra-operative bloodloss as well as the operating time.It could significantly improvethe 5-year survival rate (P<0.05),and reduce the 2 and 5-yeartumor recurrence rates (P<0.05).Moreover,its side effects werelittle.CONCLUSION Preoperative intra-arterial infusion chemo-embolization can create conditions for radical operation,lower thepostoperative recurrence rate,and improve the prognosis in thepatients with UCC.It is an effective therapy in treating UCC. | Huashu Li Fuxiang Liu Guohe Zhou Zhaoxia Mo | 2008 | Chinese Journal of Clinical Oncology2008，5，6： | 0 |
| 18 | Charge storage mechanism of copper hexacyanoferrate nanocubes for supercapacitors显示文摘The widely accepted theory concerning the electrochemical energy storage mechanism of copper hexacyanoferrate(CuHCF)for supercapacitors is that CuHCF stores charge by the reversible redox processes of Fe^3+/Fe2+couple and Cu cations are electrochemically inactive.In this work,CuHCF nanocubes(CuHCF-NC)were synthesized in the presence of potassium citrate and its electrochemical properties were tentatively studied in 1 mol/L Na2 SO4 aqueous electrolyte.Good supercapacitive performance was exhibited.The combined analyses of cyclic voltammogram(CV)and X-ray photoelectron spectroscopy(XPS)disclosed that the CuHCF nanocubes underwent the redox reactions of Fe^3+/Fe2+and Cu^2+/Cu+couples to store charges.The Cu^2+/Cu+redox couple was activated due to the strong coordination interaction between the carboxylate groups of citrate ions and surface Cu cations. | Zhaoxia Song Wei Liu Xiaofei Wei Quan Zhou Hongda Liu Zheng Zhang Guichang Liu Zhongfu Zhao | 2020 | Chinese Chemical Letters2020，31，5： | 0 |
| 19 | Analytical solution for the stress field of hierarchical defects:multiscale framework and applications显示文摘Hierarchical defects are defined as adjacent defects at different length scales.Involved are the two scales where the stress field distribution is interrelated.Based on the complex variable method and conformal mapping,a multiscale framework for solving the problems of hierarchical defects is formulated.The separated representations of mapping function,the governing equations of potentials,and the stress field are subsequently obtained.The proposed multiscale framework can be used to solve a variety of simplified engineering problems.The case in point is the analytical solution of a macroscopic elliptic hole with a microscopic circular edge defect.The results indicate that the microscopic defect aggregates the stress concentration on the macroscopic defect and likely leads to global propagation and rupture.Multiple micro-defects have interactive effects on the distribution of the stress field.The level of stress concentration may be reduced by the coalescence of micro-defects.This work provides a unified method to analytically investigate the influence of edge micro-defects within the scope of multiscale hierarchy.The formulated multiscale approach can also be potentially applied to materials with hierarchical defects,such as additive manufacturing and bio-inspired materials. | Baijian WU Sheng ZHOU Zhaoxia LI | 2021 | Applied Mathematics and Mechanics(English Edition)2021，42，2： | 0 |
| 20 | National Report on Space Medicine Progress显示文摘The development of Chinese manned space engineering has a great role in promoting the progress of Chinese space medicine. With the accelerated implementation of Chinese Space Station Program, China's space medicine has made fruitful achievements over the past three years. This report summarizes the major progress of Chinese space medicine in terms of basic research and space applications from 2016 to 2018. | LI Yinghui LI Weigang DING Bai WU Dawei LIU Zhaoxia HE Li ZHOU Wanlong XU Zi | 2018 | 空间科学学报2018，38，5： | 0 |
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