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| 1 | Machine learning guided appraisal and exploration of phase design for high entropy alloys显示文摘High entropy alloys(HEAs)and compositionally complex alloys(CCAs)have recently attracted great research interest because of their remarkable mechanical and physical properties.Although many useful HEAs or CCAs were reported,the rules of phase design,if there are any,which could guide alloy screening are still an open issue.In this work,we made a critical appraisal of the existing design rules commonly used by the academic community with different machine learning(ML)algorithms.Based on the artificial neural network algorithm,we were able to derive and extract a sensitivity matrix from the ML modeling,which enabled the quantitative assessment of how to tune a design parameter for the formation of a certain phase,such as solid solution,intermetallic,or amorphous phase.Furthermore,we explored the use of an extended set of new design parameters,which had not been considered before,for phase design in HEAs or CCAs with the ML modeling.To verify our ML-guided design rule,we performed various experiments and designed a series of alloys out of the Fe-Cr-Ni-Zr-Cu system.The outcomes of our experiments agree reasonably well with our predictions,which suggests that the ML-based techniques could be a useful tool in the future design of HEAs or CCAs. | Ziqing Zhou Yeju Zhou Quanfeng He Zhaoyi Ding Fucheng Li Yong Yang | 2019 | npj Computational Materials2019，，1： | 16 |
| 2 | V2O5 Nanospheres with Mixed Vanadium Valences as High Electrochemically Active Aqueous Zinc-Ion Battery Cathode显示文摘AV4+-V2O5 cathode with mixed vanadium valences was prepared via a novel synthetic method using VOOH as the precursor,and its zinc-ion storage performance was evaluated.The products are hollow spheres consisting of nanoflakes.The V4+-V2O5 cathode exhibits a prominent cycling performance,with a specific capacity of 140 mAhg-1 after 1000 cycles at 10 A g.1,and an excellent rate capability.The good electrochemical performance is attributed to the presence of V4+,which leads to higher electrochemical activity,lower polarization,faster ion diffusion,and higher electrical conductivity than V2O5 without V4+.This engineering strategy of valence state manipulation may pave the way for designing high-performance cathodes for elucidating advanced battery chemistry. | Fei Liu Zixian Chen Guozhao Fang Ziqing Wang Yangsheng Cai Boya Tang Jiang Zhou Shuquan Liang | 2019 | Nano-Micro Letters2019，11，2： | 12 |
| 3 | Interfacial adsorption-insertion mechanism induced by phase boundary toward better aqueous Zn-ion battery显示文摘Biphasic and multiphasic compounds have been well clarified to achieve extraordinary electrochemical properties as advanced energy storage materials.Yet the role of phase boundaries in improving the performance is remained to be illustrated.Herein,we reported the biphasic vanadate,that is,Na_(1.2)V_(3)O_(8)/K_(2)V_(6)O_(16)·1.5H_(2)O(designated as Na0.5K0.5VO),and detected the novel interfacial adsorption-insertion mechanism induced by phase boundaries.Firstprinciples calculations indicated that large amount of Zn^(2+)and H^(+)ions would be absorbed by the phase boundaries and most of them would insert into the host structure,which not only promote the specific capacity,but also effectively reduce diffusion energy barrier toward faster reaction kinetics.Driven by this advanced interfacial adsorption-insertion mechanism,the aqueous Zn/Na_(0.5)K_(0.5)VO is able to perform excellent rate capability as well as long-term cycling performance.A stable capacity of 267 mA h g^(-1)after 800 cycles at 5 A g^(-1)can be achieved.The discovery of this mechanism is beneficial to understand the performance enhancement mechanism of biphasic and multiphasic compounds as well as pave pathway for the strategic design of highperformance energy storage materials. | Lutong Shan Yiren Wang Shuquan Liang Boya Tang Yongqiang Yang Ziqing Wang Bingan Lu Jiang Zhou | 2021 | InfoMat2021，3，9： | 8 |
| 4 | Simultaneous regulation of cations and anions in an electrolyte for high-capacity, high-stability aqueous zinc–vanadium batteries显示文摘Safe,inexpensive aqueous zinc-ion batteries(AZIBs)are regarded as promising energy storage devices.However,they still face issues,including dissolution and collapse of the cathode as well as H_(2)evolution and the growth of Zn dendrites on the Zn anode.Herein,we simultaneously regulate the cations and anions in the electrolyte for high-capacity,high-stability aqueous zinc–vanadium(Zn–V)batteries based on a bimetallic cation-doped Na_(0.33)K_(0.1)V_(2)O_(5)·nH_(2)O cathode.We demonstrate that Na^(+) cations suppress cathode dissolution and restrain Zn dendrite growth on the anode via an electrostatic shield effect.We also illustrate that ClO_(4)^(-) anions participate in energy storage at the cathode and are reduced to Cl^(-),generating a protective layer on the Zn anode surface and providing a stable interface to decrease Zn dendrites and H_(2)evolution during long-term cycling.When Na^(+) and ClO_(4)^(-) are introduced into an aqueous ZnSO_(4) electrolyte,a Zn/Zn symmetric cell shows durable and reversible Zn stripping/plating for 1500 h at a current density of 1 mA cm^(-2) and with an area capacity of 1 mAh cm^(-2).Zn/Na_(0.33)K_(0.1)V_(2)O_(5)·nH_(2)O full batteries exhibit a high capacity of 600 mAh g^(-1)at 0.1 A g^(-1) and long-term cycling performance for 5000 cycles,with a capacity of 200 mAh g^(-1) at 20 Ag^(-1). | Ziqing Wang Miao Zhou Liping Qin Minghui Chen Zixian Chen Shan Guo Liangbing Wang Guozhao Fang Shuquan Liang | 2022 | eScience2022，2，2： | 8 |
| 5 | Spectral Petrov-Galerkin Methods for the Second Kind Volterra Type Integro-Differential Equations显示文摘This work is to provide general spectral and pseudo-spectral Jacobi-Petrov-Galerkin approaches for the second kind Volterra integro-differential equations.The Gauss-Legendre quadrature formula is used to approximate the integral operator and the inner product based on the Jacobi weight is implemented in the weak formulation in the numerical implementation.For some spectral and pseudo-spectral Jacobi-Petrov-Galerkin methods,a rigorous error analysis in both L2_(ω^(α,β))^(2),and L^(∞)norms is given provided that both the kernel function and the source function are sufficiently smooth.Numerical experiments validate the theoretical prediction. | Xia Tao Ziqing Xie Xiaojun Zhou | 2011 | Numerical Mathematics(Theory,Methods and Applications)2011，4，2： | 2 |
| 6 | Discrimination of mitochondrial DNA 10400 locus by SNP-operated on/off Switch显示文摘Objective:To apply reformed AS-PCR, which combined phosphorothioate-modified primers with exo+ polymerase, in single nucle- otide polymorphism discrimination of mitochondrial DNA 10400 locus. Methods: We used the mtDNA 10400 locus to design unmodi- fied and 3′phosphorothioate-modified allele-specific primers for PCR, which was performed using polymerases with and without 3′exonuclease activities. The effects of these primers on primer-extension were evaluated by agarose gel electrophoresis. Results: The unmodified primers were extended by both exo- and exo+ polymerase irrespective of whether the primers were matched or mismatched with the templates. However, the 3′phosphorothioate-modified primers with a terminal mismatch triggered an' off- switch'of exo+ polymerase when compared to exo-polymerase. Conclusion: The'on/off'switch constituted by the combination of 3′phosphorothioate-modified primers with exo+ polymerase is a cost-effective, high-throughput and reliable method for SNP typing, which will be of enormous application in association studies by single nucleotide polymorphism screening. | Mei Hong Enben Su Ziqing Chen Xiaobing Ju Qi Chen Rong Zhou | 2008 | Journal of Nanjing Medical University2008，22，6： | 1 |
| 7 | Failure probabilistic analysis of steam generator heat-transfer tubing with pitting corrosion 显示文摘 | ZHOU Binghai ZHAI Ziqing | 2011 | Engineering Failure Analysis2011，18，5： | 1 |
| 8 | Propofol prevents lung injury after intestinal ischemia-reperfusion by inhibiting the interaction between mast cell activation and oxidative stress显示文摘 | Weicheng Zhao Shaoli Zhou Weifeng Yao Xiaoliang Gan Guangjie Su Dongdong Yuan Ziqing Hei | 2014 | Life Sciences2014，，： | 1 |
| 9 | Elastic Buffering Layer on CuS Enabling High-Rate and Long-Life Sodium-Ion Storage显示文摘The latest view suggests the inactive core,surface pulverization,and poly sulfide shuttling effect of metal sulfides are responsible for their low capacity and poor cycling performance in sodium-ion batteries(SIBs).Whereas overcoming the above problems based on conventional nanoengineering is not efficient enough.In this work,erythrocyte-like CuS microspheres with an elastic buffering layer of ultrathin poly aniline(PANI) were synthesized through one-step selfassembly growth,followed by in situ polymerization of aniline.When CuS@PANI is used as anode electrode in SIBs,it delivers high capacity,ultrahigh rate capability(500 mAh gat 0.1 A g,and 214.5 mAh gat 40 A g),and superior cycling life of over 7500 cycles at 20 A g.A series of in/ex situ characterization techniques were applied to investigate the structural evolution and sodium-ion storage mechanism.The PANI swollen with electrolyte can stabilize solid electrolyte interface layer,benefit the ion transport/charge transfer at the PANI/electrolyte interface,and restrain the size growth of Cu particles in confined space.Moreover,finite element analyses and density functional simulations confirm that the PANI film effectively buffers the volume expansion,suppresses the surface pulverization,and traps the poly sulfide. | Yuanhua Xiao Feng Yue Ziqing Wen Ya Shen Dangcheng Su Huazhang Guo Xianhong Rui Liming Zhou Shaoming Fang Yan Yu | 2022 | Nano-Micro Letters2022，14，12： | 1 |
| 10 | Time-frequency signal analysis of earthquake records using mexican hat wavelets显示文摘 | Zhou Ziqing Adeli Hojjat | 2003 | Computer-Aided Civil and Infrastructure Engineering2003，18，： | 1 |
| 11 | Accumulation, transportation, and distribution of tetracycline and cadmium in rice显示文摘Co-exposure to heavy metal and antibiotic pollution might result in complexation and synergistic interactions,affecting rice growth and further exacerbating pollutant enrichment.Therefore,our study sought to clarify the influence of different Tetracycline (TC) and Cadmium(Cd) concentration ratios (both alone and combined) on rice growth,pollutant accumulation,and transportation during the tillering stage in hydroponic system.Surprisingly,our findings indicated that the interaction between TC and Cd could alleviate the toxic effects of TC/Cd on aerial rice structures and decrease pollutant burdens during root elongation.In contrast,TC and Cd synergistically promoted the accumulation of TC/Cd in rice roots.However,their interaction increased the accumulation of TC in roots while decreasing the accumulation of Cd when the toxicant doses increased.The strong affinity of rice to Cd promoted its upward transport from the roots,whereas the toxic effects of TC reduced TC transport.Therefore,the combined toxicity of the two pollutants inhibited their upward transport.Additionally,a low concentration of TC promoted the accumulation of Cd in rice mainly in the root tip.Furthermore,a certain dose of TC promoted the upward migration of Cd from the root tip.Laser ablation-inductively coupled plasma mass spectrometry demonstrated that Cd mainly accumulated in the epidermis and stele of the root,whereas Fe mainly accumulated in the epidermis,which inhibited the absorption and accumulation of Cd by the rice roots through the generation of a Fe plaque.Our findings thus provide insights into the effects of TC and Cd co-exposure on rice growth. | Chunfeng He Jini Zhou Chen Yang Zhiyi Song Junheng He Ziqing Huang Yurong Deng Jinling Wang Yu Xiong Zhi Dang | 2023 | Journal of Environmental Sciences2023，，4： | 1 |
| 12 | Propofol pretreatment attenuates remote kidney injury induced by orthotopicliver autotransplantation, which is correlated with the activation of Nrf2 inrats显示文摘 | Mian Ge Gangjian Luo Weifeng Yao Chenfang Luo Shaoli Zhou Dongdong Yuan Xinjin Chi Ziqing Hei | 2015 | Molecular Medicine Reports2015，，5： | 1 |
| 13 | Coupling of continuous FEM and LDG for convection diffusion equatioos 显示文摘 | Peng Zhu Ziqing Xie Shuzi Zhou | 2009 | Submited to Acta Mathematica Scientia2009，，： | 1 |
| 14 | CAS Array:design and assessment of a genotyping array for Chinese biobanking显示文摘Background:Chronic diseases are becoming a critical challenge to the aging Chinese population.Biobanks with extensive genomic and environmental data offer opportunities to elucidate the complex gene-environment interactions underlying their aetiology.Genome-wide genotyping array remains an efficient approach for large-scale genomic data collection.However,most commercial arrays have reduced performance for biobanking in the Chinese population.Materials and methods:Deep whole-genome sequencing data from 2641 Chinese individuals were used as a reference to develop the CAS array,a custom-designed genotyping array for precision medicine.Evaluation of the array was performed by comparing data from 384 individuals assayed both by the array and whole-genome sequencing.Validation of its mitochondrial copy number estimating capacity was conducted by examining its association with established covariates among 10162 Chinese elderly.Results:The CAS Array adopts the proven Axiom technology and is restricted to 652429 single-nucleotide polymorphism(SNP)markers.Its call rate of 99.79% and concordance rate of 99.89% are both higher than for commercial arrays.Its imputation-based genome coverage reached 98.3% for common SNPs and 63.0% for low-frequency SNPs,both comparable to commercial arrays with larger SNP capacity.After validating its mitochondrial copy number estimates,we developed a publicly available software tool to facilitate the array utility.Conclusion:Based on recent advances in genomic science,we designed and implemented a high-throughput and low-cost genotyping array.It is more cost-effective than commercial arrays for large-scale Chinese biobanking. | Zijian Tian Fei Chen Jing Wang Benrui Wu Jian Shao Ziqing Liu Li Zheng You Wang Tao Xu Kaixin Zhou | 2023 | Precision Clinical Medicine2023，6，1： | 0 |
| 15 | RBD206-sc-dimer induced robust cross-neutralization against SARS-CoV-2 and variants of concern显示文摘Dear Editor,To date,the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has caused more than 223 million confirmed cases of coronavirus disease 2019(COVID-19),including 4.6 million deaths(http://gffzze7c39cdc9e894ca6sxxpxwfuvfuuo6bux.ffgz.tsg.suse.edu.cn/).Since 2020,several SARS-CoV-2 variants including Alpha(B.1.1.7),Beta(B.1.351),Gamma(P.1),and Delta(B.1.617.2)with immune evasiveness have emerged and fast spread.In a global research effort,scientists proposed multiple effective vaccine strategies to respond to the ongoing COVID-19 pandemic.Most vaccines currently in use or in clinical development target the SARS-CoV-2 Spike(S)glycoprotein,a homotrimer decorates on the viral surface;within it,a distinct receptor-binding domain(RBD,residues 331–524)is responsible for mediating cell entry and interaction with host receptor angiotensin-converting enzyme 2(ACE2). | Chuge Zhou Xiaodong Zai Ziqing Zhou Ruihua Li Yue Zhang Yaohui Li Ying Yin Jun Zhang Junjie Xu Wei Chen | 2021 | Signal Transduction and Targeted Therapy2021，6，12： | 0 |
| 16 | Insights into the molecular mechanisms underlying responses of apple trees to abiotic stresses显示文摘Apple(Malus×domestica)is a popular temperate fruit crop worldwide.However,its growth,productivity,and quality are often adversely affected by abiotic stresses such as drought,extreme temperature,and high salinity.Due to the long juvenile phase and highly heterozygous genome,the conventional breeding approaches for stress-tolerant cultivars are time-consuming and resource-intensive.These issues may be resolved by feasible molecular breeding techniques for apples,such as gene editing and marker-assisted selection.Therefore,it is necessary to acquire a more comprehensive comprehension of the molecular mechanisms underpinning apples’response to abiotic stress.In this review,we summarize the latest research progress in the molecular response of apples to abiotic stressors,including the gene expression regulation,protein modifications,and epigenetic modifications.We also provide updates on new approaches for improving apple abiotic stress tolerance,while discussing current challenges and future perspectives for apple molecular breeding. | Xuewei Li Ziqing Ma Yi Song Wenyun Shen Qianyu Yue Abid Khan Muhammad Mobeen Tahir Xiaofei Wang Mickael Malnoy Fengwang Ma Vincent Bus Shuangxi Zhou Qingmei Guan | 2023 | Horticulture Research2023，10，8： | 0 |
| 17 | RIPK3 promotes hantaviral replication by restricting JAK-STAT signaling without triggering necroptosis显示文摘Hantaan virus(HTNV)is a rodent-borne virus that causes hemorrhagic fever with renal syndrome(HFRS),resulting in a high mortality rate of 15%.Interferons(IFNs)play a critical role in the anti-hantaviral immune response,and IFN pretreatment efficiently restricts HTNV infection by triggering the expression of a series of IFNstimulated genes(ISGs)through the Janus kinase-signal transducer and activator of transcription 1(JAK-STAT)pathway.However,the tremendous amount of IFNs produced during late infection could not restrain HTNV replication,and the mechanism remains unclear.Here,we demonstrated that receptor-interacting protein kinase 3(RIPK3),a crucial molecule that mediates necroptosis,was activated by HTNV and contributed to hantavirus evasion of IFN responses by inhibiting STAT1 phosphorylation.RNA-seq analysis revealed the upregulation of multiple cell death-related genes after HTNV infection,with RIPK3 identified as a key modulator of viral replication.RIPK3 ablation significantly enhanced ISGs expression and restrained HTNV replication,without affecting the expression of pattern recognition receptors(PRRs)or the production of type I IFNs.Conversely,exogenously expressed RIPK3 compromised the host's antiviral response and facilitated HTNV replication.RIPK3^(-/-)mice also maintained a robust ability to clear HTNV with enhanced innate immune responses.Mechanistically,we found that RIPK3 could bind STAT1 and inhibit STAT1 phosphorylation dependent on the protein kinase domain(PKD)of RIPK3 but not its kinase activity.Overall,these observations demonstrated a noncanonical function of RIPK3 during viral infection and have elucidated a novel host innate immunity evasion strategy utilized by HTNV. | Yue Si Haijun Zhang Ziqing Zhou Xudong Zhu Yongheng Yang He Liu Liang Zhang Linfeng Cheng Kerong Wang Wei Ye Xin Lv Xijing Zhang Wugang Hou Gang Zhao Yingfeng Lei Fanglin Zhang Hongwei Ma | 2023 | Virologica Sinica2023，38，5： | 0 |
| 18 | The size effect and high activity of nanosized platinum supported catalysts for low temperature oxidation of volatile organic compounds显示文摘Pt/Al_(2)O_(3) catalysts with smaller size of Pt nanoparticles were prepared by ethylene glycol reduction method in two different way and their oxidation activities for three typical VOCs(volatile organic compounds)were evaluated.The catalyst prepared by first adsorption and then reduction procedure is denoted as L-Pt/Al_(2)O_(3) while the catalyst prepared by first reduction and then loading procedure is defined as R-Pt/Al_(2)O_(3).The results show that L-Pt/Al_(2)O_(3) with the stronger interaction between Pt species and Al_(2)O_(3) exhibit smaller size of Pt nanoparticles and favorable thermal stability compared with R-Pt/Al_(2)O_(3).L-Pt/Al_(2)O_(3) is favor of the formation of more adsorbed oxygen species and more Pt^(2+)species,resulting in high catalytic activity for benzene and ethyl acetate oxidation.However,R-Pt/Al_(2)O_(3) catalysts with higher proportion of Pt^(0)/Pt^(2+)and bigger size of Pt particles exhibits higher catalytic activity for n-hexane oxidation.Pt particles in R-Pt/Al_(2)O_(3) were aggregated much more serious than that in L-Pt/Al_(2)O_(3) at the same calcination temperature.The Pt particles supported on Al_(2)O_(3) with~10 nm show the best catalytic activity for n-hexane oxidation. | Ziqing Yuan Ziyu Chen Jianxin Mao Renxian Zhou | 2021 | Chinese Journal of Chemical Engineering2021，34，11： | 0 |
| 19 | The Initial Errors in the Tropical Indian Ocean that Can Induce a Significant “Spring Predictability Barrier” for La Nina Events and Their Implication for Targeted Observations显示文摘Initial errors in the tropical Indian Ocean(IO-related initial errors) that are most likely to yield the Spring Prediction Barrier(SPB) for La Ni?a forecasts are explored by using the CESM model.These initial errors can be classified into two types.Type-1 initial error consists of positive sea temperature errors in the western Indian Ocean and negative sea temperature errors in the eastern Indian Ocean,while the spatial structure of Type-2 initial error is nearly opposite.Both kinds of IO-related initial errors induce positive prediction errors of sea temperature in the Pacific Ocean,leading to underprediction of La Nina events.Type-1 initial error in the tropical Indian Ocean mainly influences the SSTA in the tropical Pacific Ocean via atmospheric bridge,leading to the development of localized sea temperature errors in the eastern Pacific Ocean.However,for Type-2 initial error,its positive sea temperature errors in the eastern Indian Ocean can induce downwelling error and influence La Ni?a predictions through an oceanic channel called Indonesian Throughflow.Based on the location of largest SPB-related initial errors,the sensitive area in the tropical Indian Ocean for La Nina predictions is identified.Furthermore,sensitivity experiments show that applying targeted observations in this sensitive area is very useful in decreasing prediction errors of La Nina.Therefore,adopting a targeted observation strategy in the tropical Indian Ocean is a promising approach toward increasing ENSO prediction skill. | Qian ZHOU Wansuo DUAN Xu WANG Xiang LI Ziqing ZU | 2021 | Advances in Atmospheric Sciences2021，38，9： | 0 |
| 20 | A New Triangular Spectral Element Method II: Mixed Formulation and hp-Error Estimates显示文摘Mixed triangular spectral element method using nodal basis on unstructured meshes is investigated in this paper.The method is based on equivalent first order system of the elliptic problem and rectangle-triangle transforms.It fully enjoys the ten-sorial structure and flexibility in handling complex domains by using nodal basis and unstructured triangular mesh.Different from the usual Galerkin formulation,the mixed form is particularly advantageous in this context,since it can avoid the singularity in-duced by the rectangle-triangle transform in the calculation of the matrices,and does not require the evaluation of the stiffness matrix.An hp a priori error estimate is pres-ented for the proposed method.The implementation details and some numerical exam-ples are provided to validate the accuracy and flexibility of the method. | Bingzhen Zhou Bo Wang Li-Lian Wang Ziqing Xie | 2019 | Numerical Mathematics(Theory,Methods and Applications)2019，12，1： | 0 |
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