|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Reference quality assembly of the 3.5-Gb genome of Capsicum annuum from a single linked-read library显示文摘Linked-Read sequencing technology has recently been employed successfully for de novo assembly of human genomes,however,the utility of this technology for complex plant genomes is unproven.We evaluated the technology for this purpose by sequencing the 3.5-gigabase(Gb)diploid pepper(Capsicum annuum)genome with a single Linked-Read library.Plant genomes,including pepper,are characterized by long,highly similar repetitive sequences.Accordingly,significant effort is used to ensure that the sequenced plant is highly homozygous and the resulting assembly is a haploid consensus.With a phased assembly approach,we targeted a heterozygous F1 derived from a wide cross to assess the ability to derive both haplotypes and characterize a pungency gene with a large insertion/deletion.The Supernova software generated a highly ordered,more contiguous sequence assembly than all currently available C.annuum reference genomes.Over 83%of the final assembly was anchored and oriented using four publicly available de novo linkage maps.A comparison of the annotation of conserved eukaryotic genes indicated the completeness of assembly.The validity of the phased assembly is further demonstrated with the complete recovery of both 2.5-Kb insertion/deletion haplotypes of the PUN1 locus in the F1 sample that represents pungent and nonpungent peppers,as well as nearly full recovery of the BUSCO2 gene set within each of the two haplotypes.The most contiguous pepper genome assembly to date has been generated which demonstrates that Linked-Read library technology provides a tool to de novo assemble complex highly repetitive heterozygous plant genomes.This technology can provide an opportunity to cost-effectively develop high-quality genome assemblies for other complex plants and compare structural and gene differences through accurate haplotype reconstruction. | Amanda M.Hulse-Kemp Shamoni Maheshwari Kevin Stoffel Theresa A.Hill David Jaffe Stephen R.Williams Neil Weisenfeld Srividya Ramakrishnan Vijay Kumar Preyas Shah Michael C.Schatz Deanna M.Church Allen Van Deynze | 2018 | Horticulture Research2018，5，1： | 4 |
| 2 | The amazing potential of fungi:50 ways we can exploit fungi industrially显示文摘Fungi are an understudied,biotechnologically valuable group of organisms.Due to the immense range of habitats that fungi inhabit,and the consequent need to compete against a diverse array of other fungi,bacteria,and animals,fungi have developed numerous survival mechanisms.The unique attributes of fungi thus herald great promise for their application in biotechnology and industry.Moreover,fungi can be grown with relative ease,making production at scale viable.The search for fungal biodiversity,and the construction of a living fungi collection,both have incredible economic potential in locating organisms with novel industrial uses that will lead to novel products.This manuscript reviews fifty ways in which fungi can potentially be utilized as biotechnology.We provide notes and examples for each potential exploitation and give examples from our own work and the work of other notable researchers.We also provide a flow chart that can be used to convince funding bodies of the importance of fungi for biotechnological research and as potential products.Fungi have provided the world with penicillin,lovastatin,and other globally significant medicines,and they remain an untapped resource with enormous industrial potential. | Kevin D.Hyde Jianchu Xu Sylvie Rapior Rajesh Jeewon Saisamorn Lumyong Allen Grace T.Niego Pranami D.Abeywickrama Janith V.S.Aluthmuhandiram Rashika S.Brahamanage Siraprapa Brooks Amornrat Chaiyasen K.W.Thilini Chethana Putarak Chomnunti Clara Chepkirui Boontiya Chuankid Nimali I.de Silva Mingkwan Doilom Craig Faulds Eleni Gentekaki Venkat Gopalan Pattana Kakumyan Dulanjalee Harishchandra Hridya Hemachandran Sinang Hongsanan Anuruddha Karunarathna Samantha C.Karunarathna Sehroon Khan Jaturong Kumla Ruvishika S.Jayawardena Jian-Kui Liu Ningguo Liu Thatsanee Luangharn Allan Patrick G.Macabeo Diana S.Marasinghe Dan Meeks Peter E.Mortimer Peter Mueller Sadia Nadir Karaba N.Nataraja Sureeporn Nontachaiyapoom Meghan O’Brien Watsana Penkhrue Chayanard Phukhamsakda Uma Shaanker Ramanan Achala R.Rathnayaka Resurreccion B.Sadaba Birthe Sandargo Binu C.Samarakoon Danushka S.Tennakoon Ramamoorthy Siva Wasan Sriprom T.S.Suryanarayanan Kanaporn Sujarit Nakarin Suwannarach Thitipone Suwunwong Benjarong Thongbai Naritsada Thongklang Deping Wei S.Nuwanthika Wijesinghe Jake Winiski Jiye Yan Erandi Yasanthika Marc Stadler | 2019 | Fungal Diversity2019，，4： | 3 |
| 3 | Colitis and Intestinal Inflammation in IL10 ?/? Mice Results From IL-13Rα2–Mediated Attenuation of IL-13 Activity显示文摘 | Mark S. Wilson Thirumalai R. Ramalingam Aymeric Rivollier Kevin Shenderov Margaret M. Mentink–Kane Satish K. Madala Allen W. Cheever David Artis Brian L. Kelsall Thomas A. Wynn | 2011 | Gastroenterology2011，，1： | 2 |
| 4 | Seed phosphorus and inositol phosphate phenotype of barley low phytic acid geno- types 显示文摘 | John A D Allen C Kevin A Y | 2003 | Phytochemistry2003，62，5： | 1 |
| 5 | Current Utility of Staging Laparoscopy for Pancreatic and Peripancreatic Neoplasms显示文摘 | Rebekah White Corrine Winston Mithat Gonen Michael D'Angelica William Jarnagin Yuman Fong Kevin Conlon Murray Brennan Peter Allen | 2008 | Journal of the American College of Surgeons2008，，3： | 1 |
| 6 | Prognostic Value and Echocardiographic Determinants of Plasma Myeloperoxidase Levels in Chronic Heart Failure显示文摘 | W.H. Wilson Tang Wilson Tong Richard W. Troughton Maureen G. Martin Kevin Shrestha Allen Borowski Sue Jasper Stanley L. Hazen Allan L. Klein | 2007 | Journal of the American College of Cardiology2007，，24： | 1 |
| 7 | Design of Microstrip Resonators Using Balanced and Unbalanced Composite Right/Left-handed Transmission Lines显示文摘 | ALLEN KEVIN LEONG M K H | 2006 | IEEE Transactions on Microwave Theory and Techniques2006，54，7： | 1 |
| 8 | Antibacterial phenolic components of New Zealand manuka honey显示文摘 | Roderick J Weston Kevin R Mitchell Kerry L Allen | 1998 | Food Chemistry1998，，3： | 1 |
| 9 | Identification of miRNA Changes in Alzheimer’s Disease Brain andCSF Yields Putative Biomarkers and Insights into Disease Pathways显示文摘 | John P. Cogswell James Ward Ian A. Taylor Michelle Waters Yunling Shi Brian Cannon Kevin Kelnar Jon Kemppainen David Brown Caifu Chen Rab K. Prinjha Jill C. Richardson Ann M. Saunders Allen D. Roses Cynthia A. Richards | 2008 | Journal of Alzheimer’s Disease2008，，1： | 1 |
| 10 | Impact of severity of renal dysfunction on determinants of in‐hospital mortality among patients undergoing percutaneous coronary intervention显示文摘 | Puja B. Parikh Allen Jeremias Srihari S. Naidu Sorin J. Brener Fabio Lima Richard A. Shlofmitz Thomas Pappas Kevin P. Marzo Luis Gruberg | 2012 | Cathet Cardiovasc Intervent2012，，3： | 1 |
| 11 | Circulating miR-210 as a Novel Hypoxia Marker in Pancreatic Cancer显示文摘 | Allen S. Ho Xin Huang Hongbin Cao Claudia Christman-Skieller Kevin Bennewith Quynh-Thu Le Albert C. Koong | 2010 | Translational Oncology2010，，2： | 1 |
| 12 | Alternative Per- spectives on Impact: The Potential of ALMs and Altmetrics to Inform Funders about Research Impact 显示文摘 | Adam Dinsmore Liz Allen Kevin Dolby | 2014 | PLoS Biolo- gy2014，12，10： | 1 |
| 13 | Analysis of Dystrophin Deletion Mutations Predicts Age of Cardiomyopathy Onset in Becker Muscular Dystrophy显示文摘 | Rita Wen Kaspar Hugh D. Allen Will C. Ray Carlos E. Alvarez John T. Kissel Alan Pestronk Robert B. Weiss Kevin M. Flanigan Jerry R. Mendell Federica Montanaro | 2009 | Circulation: Cardiovascular Genetics2009，，： | 1 |
| 14 | Environmentally sustainable land-based marine aquaculture显示文摘 | Yossi Tal Harold J. Schreier Kevin R. Sowers John D. Stubblefield Allen R. Place Yonathan Zohar | 2008 | Aquaculture2008，，1： | 1 |
| 15 | Right Ventricular Global Longitudinal Strain Provides Prognostic Value Incremental to Left Ventricular Ejection Fraction in Patients with Heart Failure显示文摘 | Hirohiko Motoki Allen G. Borowski RDCS Kevin Shrestha Bo Hu Kenya Kusunose Richard W. Troughton W. H. Wilson Tang Allan L. Klein | 2013 | Journal of the American Society of Echocardiography2013，，： | 1 |
| 16 | Seed phosphorus and inositol phosphate phenotype of harley low phytic acid genotypes 显示文摘 | JOHN A D ALLEN C KEVIN A Y | 2003 | Phytochemistry2003，62，5： | 1 |
| 17 | Incremental Prognostic Value of Assessing Left Ventricular Myocardial Mechanics in Patients With Chronic Systolic Heart Failure显示文摘 | Hirohiko Motoki Allen G. Borowski Kevin Shrestha Richard W. Troughton W.H. Wilson Tang James D. Thomas Allan L. Klein | 2012 | Journal of the American College of Cardiology2012，，20： | 1 |
| 18 | Chemoselective oxidation of polyols with chiral pal- ladium catalysts 显示文摘 | Antonio G De Cfisci Kevin Chung Allen G 0liver | 2013 | Organometallics2013，32，7： | 1 |
| 19 | Acute Myocardial Infarction Complicated by Atrial Fibrillation in the Elderly: Prevalence and Outcomes显示文摘 | Saif S. Rathore Alan K. Berger Kevin P. Weinfurt Kevin A. Schulman William J. Oetgen Bernard J. Gersh Allen J. Solomon | 2000 | Circulation: Journal of the American Heart Association2000，，9： | 1 |
| 20 | Rectal carcinoids: The most frequent carcinoid tumor显示文摘 | Allen B. Jetmore M.D. John E. Ray M.D. J. Byron Gathright M.D. Kevin M. McMullen M.D. Terry C. Hicks M.D. Alan E. Timmcke M.D | 1992 | Diseases of the Colon & Rectum1992，，8： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员