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| 1 | A Modified Plate Assay for Rapid Screening of Potassium-Solubilizing Bacteria显示文摘The utility of microorganisms for solubilizing the unavailable forms of potassium(K) from soil has led to renewed interest in fabrication of rapid and sensitive plate assays for their isolation and screening. The present study developed a modified plate assay and compared it with previously reported methods for the isolation and screening of K-solubilizing bacteria. The newly developed plate assay is based on improved visualization of halo zone formation around the colonies on agar plates, through inclusion of an acid-base indicator dye, bromothymol blue(BTB), to modify the previously reported Aleksandrov medium. The halo zone exhibited a significant correlation(R = 0.939) with K released in liquid medium. The visualization of potential K solubilizers was improved using this method, which would help in detection of weak/non-acid producers based on secretion of organic acids in the medium. Organic acids in plate diffuse radially and form halo zones in response to reaction with the acid-base indicator dye BTB. Furthermore, K solubilization on plates with this method can be observed within 48–72 h, against the incubation time of 4–5 d needed in the earlier method. Therefore, the newly developed protocol for the plate assay was time saving, more sensitive, and beneficial in comparison to the previously reported Aleksandrov plate assay. | Mahendra Vikram Singh RAJAWAT Surender SINGH Satya Prakash TYAGI Anil Kumar SAXENA | 2016 | Pedosphere2016，26，5： | 6 |
| 2 | Microtexture and Distribution of Minerals in Hydrothermal Barite-Silica Chimney from the Franklin Seamount, SW Pacific: Constraints on Mode of Formation显示文摘An extinct hydrothermal barite-silica chimney from the Franklin Seamount of the Woodlark Basin, in the southwestern Pacific Ocean, was investigated for mineral distribution and geochemical composition. Six layers on either side of the orifice of a chimney show significant disparity in color, mineral assemblage and major element composition. Electron microscope(SEM) images reveal that the peripheral wall of the chimney is composed of colloform silica, suggesting that incipient precipitation of silica-saturated hydrothermal fluid initiated the development of the chimney wall. Intermediate layers, between the exterior wall and the inner fluid-orifice, dominate with barite and sulfides. Low Sr-to-Ba ratios(SrO/BaO = 0.015–0.017) indicate restricted fluid-seawater mixing, which causes relatively high-temperature formation of the intermediate layers. Whereas the innermost layer bordering the chimney orifice is characterized by more silica and a higher Sr-to-Ba ratio(SrO/BaO = 0.023), could have formed due to a paragenetic shift from a high-temperature active phase to a cooler waning stage of formation. A paragenetic shift is also probably responsible for the change in mineral formation mechanism that resulted in the textural variation of barite and colloform silica developed during different growth phases of this barite-silica chimney. | Durbar RAY Dalayya KOTA Pranab DAS L.Surya Prakash V.D.KHEDEKAR Anil L.PAROPKARI Abhay V.MUDHOLKAR | 2014 | Acta Geologica Sinica(English Edition)2014，88，1： | 6 |
| 3 | Role of angiotensin converting enzyme and angiotensinogen gene polymorphisms in angiotensin converting enzyme inhibitor-mediated antiproteinuric action in type 2 diabetic nephropathy patients显示文摘AIM To investigate the role of genetic variants of angiotensin converting enzyme(ACE) and angiotensinogen(AGT) genes in the antiproteinuric efficacy of ACE inhibitor therapy in diabetic nephropathy(DN) patients.METHODS In the present study, 270 type 2 diabetes mellitus patients with nephropathy were enrolled and treated with ACE inhibitor(ramipril) and followed at 6 mo for renal function and albumin excretion by estimating serum creatinine, end stage renal disease, and albumin/creatinine ratio(ACR) in urine. Genotyping of ACE I/D and AGT M235 T polymorphisms were performed by using primer specific polymerase chain reaction(PCR) and PCR-RFLP techniques, respectively. RESULTS Forty-eight percent of DN patients(responders) benefited with respect to proteinuria from ACE inhibitor therapy at 6 mo follow-up. A significant reduction in ACR was observed after 6 mo treatment with ACE inhibitor irrespective of whether DN patients were micro-albuminuric(≥ 30 and < 300 mg/g creatinine) or macro-albuminuric(≥ 300 mg/g creatinine) at the time of enrollment. However, macro-albuminuric patients(55%) showed better response to therapy. A reduction in urinary ACR was found independent of genotypes of ACE I/D and AGT M235 T polymorphisms although macro-albuminuric patients having TT genotype showed statistically insignificant increased response(72%). CONCLUSION ACE inhibitor therapy reduced urinary ACR by ≥ 30% in 50% of DN patients and the response is independent of ACE I/D and AGT M235 T polymorphisms. | Neerja Aggarwal Pawan Kumar Kare Parul Varshney Om Prakash Kalra Sri Venkata Madhu Basu Dev Banerjee Anil Yadav Alpana Raizada Ashok Kumar Tripathi | 2017 | World Journal of Diabetes2017，8，3： | 4 |
| 4 | Cluster- based multiple task allocation in distributed computing system 显示文摘 | Deo Prakash Vidyarthi Anil Kumar Tripathi | 2004 | Parallel and distributed processing symposium2004，，： | 1 |
| 5 | Historical Review and Recent Trends in Solar Drying Systems显示文摘 | Om Prakash Anil Kumar | 2013 | International Journal of Green Energy2013，，7： | 1 |
| 6 | Lycopene protects againstmemory impairment and mito-oxidative damage induced bycolchicinein rats: An evidence of nitric oxide signaling显示文摘 | Atish Prakash Anil Kumar | 2013 | EuropeanJournalofPharmacology2013，721，5： | 1 |
| 7 | Protective effect of curcumin (Curcuma longa) against d-galactose-induced senescence in mice显示文摘 | Anil Kumar Atish Prakash Samrita Dogra | 2011 | Journal of Asian Natural Products Research2011，，1： | 1 |
| 8 | Candida nivariensis as an etiologic agent of vulvovaginal candidiasis in a tertiary care hospital of New Delhi, India显示文摘 | Cheshta Sharma Sandeep Wankhede Sumathi Muralidhar Anupam Prakash Pradeep K. Singh Shallu Kathuria Deepa Anil Kumar Nilofar Khan Harbans S. Randhawa Jacques F. Meis Anuradha Chowdhary | 2013 | Diagnostic Microbiology & Infectious Disease2013，，1： | 1 |
| 9 | Clinical outcomes for nasopharyngeal cancer with intracranial extension after taxanebased induction chemotherapy and concurrent chemo-radiotherapy in the modern era显示文摘Objective:To evaluate the survival outcomes for a cohort of nasopharyngeal cancer with intracranial extension(ICE)treated with induction chemotherapy(ICT)followed by chemo-intensity-modulated radiotherapy(CTRT)at a tertiary cancer center.Methods:We retrospectively analyzed 45 patients with histologically proven,non-metastatic NPC with ICE treated at our institute between October 2008 and October 2016.Patients were classified as minor ICE or major ICE,based on the extent of ICE.All the patients received 2-3 cycles of a taxane-based ICT regimen followed by CTRT.Radiotherapy was delivered with'riskadapted'intensity-modulated radiotherapy(IMRT)technique in all patients.Results:After a median follow up of 45 months(range:8-113 months),the estimated 5-year DFS,LRFS,DMFS,and OS of the entire cohort was 58%,82%,67%and 74%respectively.On multivariate analysis,histological subtype was an independent predictor of LRFS,and age was an independent predictor of DFS.The extent of ICE showed only a trend towards worse DFS(P=0.06).None of the factors significantly predicted for DMFS or OS.Gender,N-stage,and response to ICT did not significantly affect any of the outcomes.Grade 2 or worse subcutaneous fibrosis was seen in 22%of patients and grade 2 or worse xerostomia was seen in 24%of patients at last follow up.Thirty-three percent of the patients developed clinical hypothyroidism at last follow up.None of the patients experienced any neurological or vascular complications.Conclusions:Taxane-based induction chemotherapy followed by chemo-intensity modulated radiotherapy resulted in excellent locoregional control and survival with acceptable toxicities in patients of nasopharyngeal cancer with intracranial extension.Distant metastasis continues to be the predominant problem in these patients. | Sarbani Ghosh-Laskar Avinash Pilar Carlton Johnny Kumar Prabhash Amit Joshi Jai Prakash Agarwal Tejpal Gupta Ashwini Budrukkar Vedang Murthy Monali Swain Vanita Noronha Vijay Maruthi Patil Prathamesh Pai Deepa Nair Devendra Arvind Chaukar Shivakumar Thiagarajan Gouri Pantvaidya Anuja Deshmukh Pankaj Chaturvedi Sudhir Nair Anil D’Cruz | 2020 | World Journal of Otorhinolaryngology-Head and Neck Surgery2020，6，1： | 1 |
| 10 | A novel fuzzy system for edge detec-tion in noisy image using bacterial foraging显示文摘 | Om Prakash Verma Madasu Hanmandlu Ashish Kumar Sulta-nia and Anil Singh Parihar | 2013 | MultidimensionalSystems and Signal Processing2013，24，1： | 1 |
| 11 | Molecular phylogenetics and biogeography of the Neocellia Series of Anopheles mosquitoes in the Oriental Region显示文摘 | Katy Morgan Samantha M. O’Loughlin Fong Mun-Yik Yvonne-Marie Linton Pradya Somboon Sein Min Pe Than Htun Simone Nambanya Indira Weerasinghe Tho Sochantha Anil Prakash Catherine Walton | 2009 | Molecular Phylogenetics and Evolution2009，，3： | 1 |
| 12 | Fuzzy Logic Based Group Maturity Rating for Software Performance Prediction显示文摘由市场要求开车,软件服务组织收养了各种各样的软件工程进程模特儿(例如能力成熟模型(CMM ) ,能力成熟模型集成(CMMI ) , ISO 9001:2000,等等) 并且工程管理概念的实践在知识的工程管理身体定义。当这毫无疑问帮助了组织把一些方法带进软件开发疯狂时,总是在那里存在对以这些的实践在组织以内比较各种各样的组的一个要求定义过程模型。尽管在那里存在为比较的许多度量标准,以技术考虑工程的变化,生命周期,等等,发现迎合这的一个单个度量标准是一项困难的任务。这篇论文为到达一在组织以内在组成熟上评价建议一个模型。就软件大小的语言学或不精确、不明确的性质而言,模糊逻辑途径被用于建议模型。没有象技术或生命周期差别一样的障碍,建议模型帮助组织在它以内把不同的组与合理精确作比较。关键词组成熟等级 - 模糊逻辑 - 模糊集合 - 历史的数据 - 软件工程 A. K。Verma 收到了 B.Tech (爱人) 和博士(Engg ) 从电力工程的部门的学位, IIT Kharagpur。自从 1988,他作为一个教师与 IIT 孟买。他当前是在可靠性工程的一个教授,在 IIT 孟买的电力工程的部门。他让超过 130 研究论文到他的信用并且在 IIT 孟买监督了十八篇博士论文和七十篇主人鈥檚 论文。他是 IETE 技术评论, Performability 工程的国际杂志,可靠性的国际杂志,质量和设计的安全的电子学,通讯与信息技术的优秀管理上的特刊的一个客人编辑,并且在各种各样的杂志的编委上。他是各种各样的国际会议, ICQRC 2001, ICMD 2002, ICQRIT 2003, ICQRIT 2006 和 ICRESH 2005 的一个保护人的一个会议主席。他在模糊可靠性工程上写作了一本书:概念和应用程序。他是 IEEE 的一个高级成员和 IETE 的生活家伙。他可靠性工程上的研究兴趣在软件工程包括学科交差的应用程序,计算,维护和力量系统。靛蓝 R 从 Calicut 的大学在 mechanical engineering 收到了 B.Tech 学位, Kerala,印度,在 1995。他当前与限制的拉尔森与 Toubro Infotech 一起作为优秀经理正在工作并且在 IIT 孟买追求他的博士学位, Mumbai,印度。他的研究兴趣用 neuro 模糊的途径包括软件可靠性和软件预言。Om Prakash 耆那教徒从 McGill 大学在电力工程收到了博士学位,加拿大蒙特利尔。他也在象印度工学院, Kharagpur,和 Birla 工学院一样的首要的印度机构学习了, Mesra, Ranchi。他当前领导在限制的拉尔森与 Toubro Infotech 请教实践的过程。他是为 ISO 9001:2000 的一个证明的铅听者,为优秀管理的一个证明检查人并且一限制了六条西格马黑带。他在象 IEEE 交易一样的各种各样的国际杂志出版了几篇技术论文。他的研究兴趣为软件专业人员在软件质量上包括试验性的软件工程,软件预言和变化范例。 | A.K.Verma Anil R Om Prakash Jain | 2007 | International Journal of Automation and computing2007，4，4： | 1 |
| 13 | Role of Nuclear Receptor on Regulation of BDNF and Neuroinflammation in Hippocampus of β-Amyloid Animal Model of Alzheimer’s Disease显示文摘 | Atish Prakash Anil Kumar | 2014 | Neurotoxicity Research2014，，： | 1 |
| 14 | Antimalarial activity of a novel series of artemisinin-derived 1, 2, 3-triazole dimers显示文摘Objective: To obtain suitable artimisinin-based drug candidates with high antimalarial activity.Methods: Three different reaction schemes were used to synthesize a total of 15 artemisininbased compounds.The first synthetic scheme involved the synthesis of diazido aliphatic and aromatic compounds from commercially available dihalides and azido derivatives of artemisinin.The second scheme consisted of the reaction of dibromoaliphatic compounds with sodium azide in dimethylformamide which yielded the desired compounds.Artemisinin-based compounds on treatment with sodium azide and bromotrimethylsilane in dichloromethane produced the most potent compound GB-2.Another potent compound GB-1 was synthesized from artemisinin by treatment with alcohols in the presence of Aberlyst-15 in anhydrous dichloromethane.The third scheme involved the Huisgen 1,3-dipolar cycloaddition between the synthesized aliphatic and aromatic diazides and two alkyne derivatives of artemisinin to obtain the desired artemisinin dimers with average yields.Results: The best in vitro antiplasmodial activity was shown by the compound GB-2 registering IC_(50) value 0.066 μg/mL against chloroquine-sensitive and 0.865 μg/mL against chloroquineresistant strains of Plasmodium falciparum.It suppressed 59.0% parasitaemia in vivo of rodent malaria parasite Plasmodium berghei in Swiss albino model at 50 μg/kg body weight dosage.Molecular docking interactions of Plasmodium falciparum ATP6(PfATP6) protein revealed strong bonding of GB-2 with Thr255 residue which is likely to be the reason for excellent antimalarial activity of this compound.Conclusion: Two compounds GB-1 and GB-2 exhibited excellent in vitro antiplasmodial activity and fair in vivo antimalarial activity.Of the two, GB-2 showed better activity which could be attributed to its strong bonding interactions with Thr255 as evidenced from the molecular docking study.Study helped in identifying artemisinin analogues possessing good antimalarial properties and further research in structural alterations of the selected molecules should be carried out which may result in obtaining potent drug candidates against the malarial parasite. | Kabita Gogoi Gokul Baishya Biswajit Saikia Nabin Chandra Barua Chandrajit Dohutia Akalesh Kumar Verma Anil Prakash | 2019 | Asian Pacific Journal of Tropical Medicine2019，12，5： | 0 |
| 15 | Phytochemical screening and wound healing potential of Cuscuta reflexa显示文摘The present study was to investigate pharmacognostical, phytochemical and pharmacological properties of extracts from stem of Cuscuta reflexa Roxb. Standard procedures have been followed to evaluate the pharmacognostical properties and preliminary screening of phytochemicals of Cuscuta reflexa Roxb. Albino Wistar rats(either sex) weighing 150–200 g were taken and made to acclimatize by providing them with the appropriate room conditions in the experimental room. Excision wound model has been selected for analgesic and wound healing activity for evaluating potential of the water-extract and ethanolic extract from the stem of Cuscuta reflexa Roxb. The macroscopic and microscopic studies showed the various characteristic features of stems. Preliminary screening of phytochemicals reveled that alkaloids, glycosides, flavonoids were the major groups of phytochemicals present in the successive extracts. Water and ethanolic extracts from stem of Cuscuta reflexa Roxb at 200 mg/kg and 400 mg/kg were able to alleviate pain and wounds. It is concluded that the stems of Cuscuta reflexa Roxb have a markedly therapeutic potential to heal wound and may provide the pharmacological basis for its folk uses. | Tapsya Gautam Surya Prakash Gautam Raj K.Keservani Anil Kumar Sharma | 2015 | Journal of Chinese Pharmaceutical Sciences2015，24，5： | 0 |
| 16 | 扭带式换热器水热关联的机器学习辅助建模显示文摘本文介绍了机器学习(ML)算法在带扭带插件的换热器传热关联(如努塞尔数和摩擦系数)建模中的应用.采用换热器在不同雷诺数(Re)、扭转比(t)、穿孔率(p)和不同扭带数(n)下的实验数据进行相关建模.在数据驱动的代理建模中使用了三种机器学习算法:多项式回归(PR)、随机森林(RF)和人工神经网络(ANN).为了保证模型的通用性,对ML模型的超参数进行了优化,分析了不同ML算法的性能参数(如R 2和MAE).结果表明,在不同的测试数据集上,人工神经网络对传热系数的预测优于PR和RF的预测.基于本文分析内容,对未来数据驱动的传热关联建模工作和类似研究提出了建议. | Jyoti Prakash Panda Bipin Kumar Anil Kumar Patil Manoj Kumar Ravi Kumar | 2023 | Acta Mechanica Sinica2023，39，1： | 0 |
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