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| 1 | The effect of land use structure on the distribution of soil nutrients in the hilly area of the Loess Plateau,China显示文摘The irrational land use is one of the main reasons for the soil erosion and nutrient loss in the loess hilly area of China. In this project, 4 types of typical land use structure of sustain ment for about 15 years in the loess hill slope are selected to study the effect of land use structure on the distribution of soil nutrients. From hill bottom to hill top, the patterns of land use types are:, grassland-slope farmland-forest, slope farmland-grassland-forest, terrace-grassland-forest and slope farmland-forest-grassland. By measuring the contents of the total N, total P, available N, available P and organic matter of soils, the results show that the land use structure types of slope farmland-grassland-forest and terrace-grassland-forest have a better capacity to maintain the soil nutrients. | Bojie Fu Keming Ma Huafeng Zhou Liding Chen | 1999 | Chinese Science Bulletin1999，44，8： | 32 |
| 2 | Reversing drug resistance of soft tumor-repopulating cells by tumor cell-derived chemotherapeutic microparticles显示文摘颠倒使人重新住入肿瘤的房间(TRC ) 的药抵抗或起源的发展中的新奇途径像房间的癌症房间是迫切临床的需要改进癌症病人的结果。这里,我们显示出用肿瘤颠倒 TRC 的药抵抗的一条创新途径包含反肿瘤药的导出房间的 microparticles (T-MPs ) 。由比区分的癌症房间更可变形的优点, TRC 优先地收起 T-MPs 在进入房间以后释放反肿瘤药,它接着导致 TRC 的死亡。内在的机制包括防碍药流出并且支持这些药的原子入口。我们的调查结果在用有希望的临床的应用程序颠倒 TRC 的药抵抗在 T-MPs 的举起和一条新奇途径的有效性表明肿瘤房间柔软的重要性。 | Jingwei Ma Yi Zhang Ke Tang Huafeng Zhang Xiaonan Yin Yong Li Pingwei Xu Yanling Sun Ruihua Ma Tiantian Ji Junwei Chen Shuang Zhang Tianzhen Zhang Shunqun Luo Yang Jin Xiuli Luo Chengyin Li Hongwei Gong Zhixiong Long Jinzhi Lu Zhuowei Hu Xuetao Cao Ning Wang Xiangliang Yang Bo Huang | 2016 | Cell Research2016，26，6： | 17 |
| 3 | Imbalance of Interleukin 18 and Interleukin 18 Binding Protein in Patients with Lupus Nephritis显示文摘评估 interleukin 的平衡地位 18 ( IL-18 )并且 interleukin 在在有豺狼座肾炎(行)和主要肾病的症候群( PNS )的病人的循环的 18 有约束力的蛋白质( IL-18BP ),在 IL-18 和 IL-18BP 的外部血 mononuclear 房间( PBMC )的血浆层次以及 mRNA 表示被 ELISA 和 RT-PCR 分别地测量。IL-18/IL-18BP 的比率也是计算的。当仅仅 IL-18BP 在 PNS 增加了时,当时,血浆 IL-18 和 IL-18BP 在行病人显著地增加了,它在行然而并非在 PNS 病人导致了 IL-18/IL-18BP 的提高的比率与正常控制相比。相反,增加了 IL-18 mRNA 的水平仅仅在行然而并非在 PNS 组被检测,尽管在在两个组的 PBMC 的 IL-18BP mRNA 表情在控制比那高。IL-18 和 IL-18BP 的不平衡可能涉及行,一条治疗学的途径基于是为行要发展的贵重物品的致病。细胞与分子的免疫学。2006; 3 (4 ): 303-306。 | Dong Liang Wenfeng Ma Cuiwei Yao Huafeng Liu Xiaowen Chen | 2006 | Cellular & Molecular Immunology2006，3，4： | 10 |
| 4 | Low-dose real-time X-ray imaging with nontoxic double perovskite scintillators显示文摘X-rays are widely used in probing inside information nondestructively,enabling broad applications in the medical radiography and electronic industries.X-ray imaging based on emerging lead halide perovskite scintillators has received extensive attention recently.However,the strong self-absorption,relatively low light yield and lead toxicity of these perovskites restrict their practical applications.Here,we report a series of nontoxic double-perovskite scintillators of Cs_(2)Ag_(0.6)Na_(0.4)In_(1-y)Bi_(y)Cl_(6).By controlling the content of the heavy atom Bi^(3+),the X-ray absorption coefficient,radiative emission efficiency,light yield and light decay were manipulated to maximise the scintillator performance.A light yield of up to 39,000±7000 photons/MeV for Cs_(2)Ag_(0.6)Na_(0.4)In_(0.85)Bi_(0.15)Cl_(6) was obtained,which is much higher than that for the previously reported lead halide perovskite colloidal CsPbBr_(3)(21,000 photons/MeV).The large Stokes shift between the radioluminescence(RL)and absorption spectra benefiting from self-trapped excitons(STEs)led to a negligible selfabsorption effect.Given the high light output and fast light decay of this scintillator,static X-ray imaging was attained under an extremely low dose of ∼1μGy_(air),and dynamic X-ray imaging of finger bending without a ghosting effect was demonstrated under a low-dose rate of 47.2μGy_(air) s^(−1).After thermal treatment at 85℃ for 50 h followed by X-ray irradiation for 50 h in ambient air,the scintillator performance in terms of the RL intensity and X-ray image quality remained almost unchanged.Our results shed light on exploring highly competitive scintillators beyond the scope of lead halide perovskites,not only for avoiding toxicity but also for better performance. | Wenjuan Zhu Wenbo Ma Yirong Su Zeng Chen Xinya Chen Yaoguang Ma Lizhong Bai Wenge Xiao Tianyu Liu Haiming Zhu Xiaofeng Liu Huafeng Liu Xu Liu Yang(Michael)Yang | 2020 | Light(Science & Applications)2020，9，1： | 9 |
| 5 | Research on Startup Reliability of Ultrasonic Motors显示文摘作为一种在航空航天和武器系统有着广泛用途的新型微电机,超声电机的启动可靠性影响了其进一步的推广应用。该文通过理论分析将影响电机可靠启动的因素定位为定、转子摩擦界面阻力的增加以及定子的非线性振动,其中摩擦界面阻力增加包括摩擦材料嵌入定子槽中以及摩擦材料与定子的粘接。结合仿真分析和实验研究,证明超声电机定子振动的非线性是影响电机可靠启动的根本原因,越靠近共振频率非线性越严重,而定、转子接触界面的粘接以及摩擦材料嵌入定子齿使定子谐振频率升高,也就使原有工作频率更接近共振频率,从而导致电机定频启动困难。最后提出利用定子振动的非线性,采取降频启动的方法,可有效提高电机启动可靠性,为超声电机的推广应用打下良好基础。 | LI Huafeng DING Qingjun CHEN Chao | 2013 | 中国电机工程学报2013，33，9： | 7 |
| 6 | Design of freeform geometries in a MEMS accelerometer with a mechanical motion preamplifier based on a genetic algorithm显示文摘This paper describes a novel,semiautomated design methodology based on a genetic algorithm(GA)using freeform geometries for microelectromechanical systems(MEMS)devices.The proposed method can design MEMS devices comprising freeform geometries and optimize such MEMS devices to provide high sensitivity,large bandwidth,and large fabrication tolerances.The proposed method does not require much computation time or memory.The use of freeform geometries allows more degrees of freedom in the design process,improving the diversity and performance of MEMS devices.A MEMS accelerometer comprising a mechanical motion amplifier is presented to demonstrate the effectiveness of the design approach.Experimental results show an improvement in the product of sensitivity and bandwidth by 100%and a sensitivity improvement by 141%compared to the case of a device designed with conventional orthogonal shapes.Furthermore,excellent immunities to fabrication tolerance and parameter mismatch are achieved. | Chen Wang Xiaoxiao Song Weidong Fang Fang Chen Ioannis Zeimpekis Yuan Wang Aojie Quan Jian Bai Huafeng Liu Gerold Schropfer Chris Welham Michael Kraft | 2020 | Microsystems & Nanoengineering2020，6，1： | 6 |
| 7 | Networking retinomorphic sensor with memristive crossbar for brain-inspired visual perception显示文摘Compared to human vision,conventional machine vision composed of an image sensor and processor suffers from high latency and large power consumption due to physically separated image sensing and processing.A neuromorphic vision system with brain-inspired visual perception provides a promising solution to the problem.Here we propose and demonstrate a prototype neuromorphic vision system by networking a retinomorphic sensor with a memristive crossbar.We fabricate the retinomorphic sensor by using WSe_(2)/h-BN/Al_(2)O_(3)van der Waals heterostructures with gate-tunable photoresponses,to closely mimic the human retinal capabilities in simultaneously sensing and processing images.We then network the sensor with a large-scale Pt/Ta/Hf O_(2)/Ta one-transistor-one-resistor(1 T1 R)memristive crossbar,which plays a similar role to the visual cortex in the human brain.The realized neuromorphic vision system allows for fast letter recognition and object tracking,indicating the capabilities of image sensing,processing and recognition in the full analog regime.Our work suggests that such a neuromorphic vision system may open up unprecedented opportunities in future visual perception applications. | Shuang Wang Chen-Yu Wang Pengfei Wang Cong Wang Zhu-An Li Chen Pan Yitong Dai Anyuan Gao Chuan Liu Jian Liu Huafeng Yang Xiaowei Liu Bin Cheng Kunji Chen Zhenlin Wang Kenji Watanabe Takashi Taniguchi Shi-Jun Liang Feng Miao | 2021 | National Science Review2021，8，2： | 5 |
| 8 | Polyethyleneimine-modified calcium carbonate nanoparticles for p53 gene delivery显示文摘In this study,calcium carbonate(CaCO3)nanoparticles with spherical structure were regulated by arginine and successfully synthesized via a facile co-precipitation method.The average particle size of as-prepared CaCO3 was about 900 nm.The properties of nanostructured CaCO3 particles were characterized by scanning electron microscope,Fourier transform infrared spectroscopy,Xray diffraction and size distribution.After modified with polyethyleneimine(PEI),the ability of PEICaCO3 nanoparticles to carry GFP-marked p53 gene(pEGFP-C1-p53)into cancer cells to express P53 protein were studied.Meanwhile,the cytotoxicity,transfection efficiency,cells growth inhibition and the ability to induce apoptosis by expressed P53 protein were conducted to evaluate the performances of PEI-CaCO3 nanoparticles.The results show that prepared PEI-CaCO3 nanoparticles had good biocompatibility and low cytotoxicity in a certain concentration range.PEI-CaCO3 effectively transfected pEGFP-C1 gene into epithelial-like cancer cells.And with the expression of GFP-P53 fusion protein,pEGFP-C1-p53-gene-loaded PEI-CaCO3 particles significantly reduced the proliferation of cancer cells.These findings indicate that our PEI-modified CaCO3 nanoparticles are potential to be successfully used as carriers for gene therapy. | Cen Chen Huafeng Han Wei Yang Xiaoyuan Ren Xiangdong Kong | 2016 | Regenerative Biomaterials2016，3，1： | 4 |
| 9 | Enhancement of oral bioavailability and anti-Parkinsonian efficacy of resveratrol through a nanocrystal formulation显示文摘Resveratrol(RES),a non-flavonoid polyphenol extracted from a wide variety of plants,exhibits neuroprotective activities against Parkinson’s disease(PD).However,undesirable water solubility of RES reduces its oral bioavailability and demonstrates lowefficacy in blood and brain,thus limiting its application.In present study,a nanocrystal formulation of RES(RES-NCs)was developed to enhance its oral bioavailability and delivery into brain for PD treatment.RES-NCs were fabricated with hydroxypropyl methylcellulose(HPMC)stabilizer via antisolvent precipitation approach.The obtained RES-NCs displayed the particle size of 222.54±1.66 nm,the PDI of 0.125±0.035,the zeta potential of−9.41±0.37mV,and a rapid in vitro dissolution rate.Molecular dynamics simulation of RES and HPMC revealed an interaction energy of−68.09 kJ/mol and a binding energy of−30.98±0.388 kJ/mol,indicating that the spontaneous binding between the two molecules is through van der Waals forces.RES-NCs conferred enhanced cellular uptake as well as improved permeability relative to pure RES.In addition,RES-NCs were able to protect neurons against cytotoxicity induced by MPP+.Meanwhile,RES-NCs exerted no significant toxic effects on zebrafish embryos and larvae,and did not influence their survival and hatching rates.When orally administered to rats,RES-NCs exhibited more favorable pharmacokinetics than pure RES,with higher plasma and brain concentrations.More importantly,MPTP-induced PD mice showed notable improvements in behavior,attenuated dopamine deficiency,and elevated levels of dopamine and its metabolites after the treatment with RES-NCs.Furthermore,immunoblot analysis revealed that the neuroprotective role of RES-NCsmay be at least partially mediated by Akt/Gsk3βsignaling pathway.Taken altogether,RES-NCs can serve as a potential treatment modality for PD,offering means of improving RES oral bioavailability and brain accumulation. | Sha Xiong Wei Liu Yile Zhou Yousheng Mo Yao Liu Xiaojia Chen Huafeng Pan Dongsheng Yuan QiWang Tongkai Chen | 2020 | Asian Journal of Pharmaceutical Sciences2020，15，4： | 3 |
| 10 | Detection of Variants of B.1.617 Lineage from Five Returning Chinese Nationals at a Guangxi-Vietnam Border Port——Guangxi Zhuang Autonomous Region,China,April 2021显示文摘A 47-year-old male(Patient A)passenger from Vietnam whose nucleic acid results for coronavirus disease 2019(COVID-19),also known as severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),were positive at Pingxiang Customs on April 29,2021,and subsequently confirmed by Guangxi CDC laboratories on April 30. | Ning Kang Yinpin Liu Fuyin Bi Jing Wang Huafeng Chen Jing Wang Zhenli Liang Min Chen Guangwu Wei Aiming Li Yonghong Li Bao Lu Zhenling Jiang Yi Tan Ge Zhong Mei Lin Yu Ju | 2021 | China CDC weekly2021，3，30： | 3 |
| 11 | Research Review on Marine Search and Rescue显示文摘 | CHEN Xinqiang SHI Chaojian WANG Shengzheng WU Huafeng XU Tie KE Ruimin | 2017 | Journal of Shipping and Ocean Engineering2017，7，3： | 2 |
| 12 | Design of a large-range rotary microgripper with freeform geometries using a genetic algorithm显示文摘This paper describes a novel electrostatically actuated microgripper with freeform geometries designed by a genetic algorithm.This new semiautomated design methodology is capable of designing near-optimal MEMS devices that are robust to fabrication tolerances.The use of freeform geometries designed by a genetic algorithm significantly improves the performance of the microgripper.An experiment shows that the designed microgripper has a large displacement(91.5μm)with a low actuation voltage(47.5 V),which agrees well with the theory.The microgripper has a large actuation displacement and can handle micro-objects with a size from 10 to 100μm.A grasping experiment on human hair with a diameter of 77μm was performed to prove the functionality of the gripper.The result confirmed the superior performance of the new design methodology enabling freeform geometries.This design method can also be extended to the design of many other MEMS devices. | Chen Wang Yuan Wang Weidong Fang Xiaoxiao Song Aojie Quan Michiel Gidts Hemin Zhang Huafeng Liu Jian Bai Sina Sadeghpour Michael Kraft | 2022 | Microsystems & Nanoengineering2022，8，1： | 2 |
| 13 | Structural iMoSIFT for Human Action Recognition显示文摘Classic local space-time features are successful representations for action recognition in videos. However, these features always confuse object motions with camera motions, which seriously affect the accuracy of action recognition. In this paper, we propose improved motion scale-inviriant feature transform(iMoSIFT) algorithm to eliminate the negative effects caused by camera motions. Based on iMoSIFT, we consider the spatial-temporal structure relationship among iMoSIFT interest points, and adopt locally weighted word context descriptors to code this relationship. Then, we use two-layer BOW representation for every video clip. The proposed approach is evaluated on available datasets, namely Weizemann, KTH and UCF sports. The experimental results clearly demonstrate the effectiveness of the proposed approach. | CHEN Huafeng CHEN Jun HU Ruimin | 2016 | Wuhan University Journal of Natural Sciences2016，21，3： | 2 |
| 14 | An ACOA-AFSA fusion routing algorithm for underwater wireless sensor network显示文摘 | WU Huafeng CHEN Xinqiang SHI Chaojian | 2012 | International Journal of Distributed Sensor Networks2012，2012，2012： | 1 |
| 15 | Anti-hyperuricemic and nephroprotective effects of Smilax china L.显示文摘 | Lvyi Chen Huafeng Yin Zhou Lan Shuwei Ma Chunfeng Zhang Zhonglin Yang Ping Li Baoqin Lin | 2011 | Journal of Ethnopharmacology2011，，2： | 1 |
| 16 | Nanogold–polyaniline–nanogold microspheres-functionalized molecular tags for sensitive electrochemical immunoassay of thyroid-stimulating hormone显示文摘 | Yuling Cui Huafeng Chen Li Hou Bing Zhang Bingqian Liu Guonan Chen Dianping Tang | 2012 | Analytica Chimica Acta2012，，： | 1 |
| 17 | Investment-cash flow sensitivity cannot be a good measure of financial constraints: Evidence from the time series显示文摘 | Huafeng (Jason) Chen Shaojun (Jenny) Chen | 2011 | Journal of Financial Economics2011，，2： | 1 |
| 18 | Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis显示文摘 | Carmen Wong Huafeng Zhang Daniele Gilkes Jasper Chen Hong Wei Pallavi Chaturvedi Maimon Hubbi Gregg Semenza | 2012 | Journal of Molecular Medicine2012，，7： | 1 |
| 19 | Investment-cash flow sensitivity cannot be a good measure of financial constraints: Evidence from the time series显示文摘 | Huafeng (Jason) Chen Shaojun (Jenny) Chen | 2011 | Journal of Financial Economics2011，，2： | 1 |
| 20 | Firm Life Expectancy and the Heterogeneity of the Book-to-Market Effect显示文摘 | Huafeng (Jason) Chen | 2011 | Jour- nal of Financial Economies2011，，100： | 1 |
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