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| 1 | In situ synthesis of graphene oxide/gold nanorods theranostic hybrids for efficient tumor computed tomography imaging and photothermal therapy显示文摘Graphene 氧化物 / 黄金 nanorod (GO/GNR ) nanohybrids 被混合聚苯乙烯 sulfonate (PSS ) 在房间温度在 situ 生长方法与 GO-seed-mediated 和 gold-seed-mediated 综合 functionalized 去,第二等的生长答案,和金种子。与 GO/GNRs 或 graphene (G)/GNRs 的前 situ 准备方法相比,在里面 GO/GNRs 的 situ 合成在他们的附件前处理了 GNR 的聚集的问题到 GO 上。方法直接、环境友好。GO/GNRs 在 vitro 显示出显著 photothermal 效果。GO/GNR nanohybrids 的温度在女人上从 25 ~ 49.9 增加了光谱为宽事件角度的范围(365 ~ 1,100 nm )(0io 是超过 6.00 ~ 10 个病人和 35 age-/gender-matched 控制(吝啬的 s 吗?? | Bingmei Sun Jinrui Wu Shaobin Cui Huanhuan Zhu Wei An Qingge Fu Chengwei Shao Aihua Yao Bingdi Chen Donglu Shi | 2017 | Nano Research2017，10，1： | 4 |
| 2 | Whole-process design and experimental validation of landing gear lower drag stay with global/local linked driven optimization strategy显示文摘Landing gear lower drag stay is a key component which connects fuselage and landing gear and directly effects the safety and performance of aircraft takeoff and landing. To effectively design the lower drag stay and reduce the weight of landing gear, Global/local Linked Driven Optimization Strategy(GLDOS) was developed to conduct the overall process design of lower drag stay in respect of optimization thought. The whole-process optimization involves two stages of structural conceptual design and detailed design. In the structural conceptual design, the landing gear lower drag stay was globally topologically optimized by adopting multiple starting points algorithm. In the detailed design, the local size and shape of landing gear lower drag stay were globally optimized by the gradient optimization strategy. The GLDOS method adopts different optimization strategies for different optimization stages to acquire the optimum design effect. Through the experimental validation, the weight of the optimized lower dray stay with the developed GLDOS is reduced by 16.79% while keeping enough strength and stiffness, which satisfies the requirements of engineering design under the typical loading conditions. The proposed GLDOS is validated to be accurate and efficient in optimization scheme and design cycles. The efforts of this paper provide a whole-process optimization approach regarding different optimization technologies in different design phases, which is significant in reducing structural weight and enhance design tp wid 1 precision for complex structures in aircrafts. | Chengwei FEI Haotian LIU Zhengzheng ZHU Liqiang AN Shaolin LI Cheng LU | 2021 | Chinese Journal of Aeronautics2021，34，2： | 2 |
| 3 | Energy conversion in woodpecker on successive peckings and its role on anti-shock protection of brain显示文摘To investigate the mechanism of brain protection of woodpecker,we built a finite element model of a whole woodpecker using computed topography scanning technique and geometry modeling.Dynamic analyses reveal:(i)99.7%of the impact energy is converted into strain energy in the bulk of body and 0.3%is converted into strain energy in the head after three successive peckings,indicating the majority of the impact energy is stored in the bulk of body;(ii)the strain energy in brain is mainly converted into the dissipated energy,alleviating the mechanical injury to brain;(iii)the deformation and the effective energy dissipation of the beaks facilitate the decrease of the stress and impact energy transferred to the brain;(iv)the skull and dura mater not only provide the physical protection for the brain,but also diminish the strain energy in the brain by energy dissipation;(v)the binding of skull with the hyoid bone enhances the anti-shock ability of head.The whole body of the woodpecker gets involved in the energy conversion and forms an efficient anti-shock protection system for brain. | ZHU ZhaoDan ZHANG Wei WU ChengWei | 2014 | Science China(Technological Sciences)2014，57，7： | 2 |
| 4 | Frequency Analysis and Anti-Shock Mechanism of Woodpecker's Head Structure显示文摘 | Zhaodan Zhu Chengwei Wu Wei Zhang | 2014 | Journal of Bionic Engineering2014，11，2： | 2 |
| 5 | Measurement and modeling for solubility of 3-hydroxybenzaldehyde and its mixture with 4-hydroxybenzaldehyde in supercritical carbon dioxide显示文摘 | Hao Wu Jing Zhu Yiwei Wang Chengwei Chang Junsu Jin | 2016 | Fluid Phase Equilibria2016，，： | 1 |
| 6 | Boiling Point Distribution of Hydrocarbon Types in Diesel Using Solid-Phase Extraction Followed by GC/FID-EIMS显示文摘在这篇论文,一个方法被建立在柴油机决定烃类型的沸腾的点分发。柴油机样品借助于稳固阶段的抽取(SPE ) 被分开成 saturate 和芳香的部分,并且每部分被 GC/FID-EIMS 分析。根据在在色层谱煮 n 石蜡的点和保留时间之间的关系,百分比浸透并且在每温度间隔的 aromatics 被计算。根据在每温度间隔的 saturate 和芳香的部分的平均集体系列,样品的烃类型通过典型集体碎片的求和被识别。用这个方法,在柴油机的作文的变化在 hydrotreating 过程期间被学习。结果证明 aromatics 的加氢在 hydrotreating 过程期间是主要反应。越多包围 aromatics,加氢反应越 easier 将发生。aromatics 经由加氢和浸透过程被变换成环烷,导致在 hydrotreated 油的低沸腾的点部分的增加。 | Li Chengwei Tian Songbai Liu Zelong Zhu Xinyi | 2008 | China Petroleum Processing & Petrochemical Technology2008，10，3： | 1 |
| 7 | Ice-volume and insolation influences on hydroclimate changes in central eastern China during the antepenultimate glacial period显示文摘The rainfall changes in East Asian summer monsoon(EASM)regions on the orbital timescale remain controversial due to the lack of reliable rainfall records.Here,we present new multiproxy records(δ^(18)O,δ^(13)C,Sr/Ca and Mg/Ca)of a230Thdated stalagmite from Hulu Cave in central eastern China.Multiproxy records reconstruct a regional hydroclimate history from 340 to 261 kyr BP(thousand years before present),approximately covering the antepenultimate glacial period.Theδ^(18)O record is dominated by the precessional cycles,suggesting that EASM responds to changes in Northern Hemisphere summer insolation(NHSI)on the orbital timescale.Significant correlations amongst theδ^(13)C,Sr/Ca and Mg/Ca suggest that a common factor,i.e.,the local hydrological cycle,controlled their variability,and their leading principal component can be used as a proxy linked to regional rainfall.This composite record bears a good similarity to those from the Chinese Loess Plateau,showing a gradually decreasing rainfall during the antepenultimate glacial period,consistent with changes in global ice volume.Superimposed on the long-term trend,three relative wetter intervals were responding to the higher NHSI periods,suggesting that EASM rainfall variability was induced by integrated effects of global ice volume and NHSI.The increased ice sheets and lower NHSI resulted in an increased meridional temperature gradient and southward shift of the westerlies,which shortened the duration of Meiyu and midsummer rainfall.The differences between the rainfall record and the stalagmiteδ^(18)O record indicate that the latter represents the overall EASM intensity linked to monsoon circulation,but does not directly reflect the rainfall changes at the cave sites. | Quan WANG Shayue YUAN Yijia LIANG Kan ZHAO Qingfeng SHAO Zhenqiu ZHANG Junji ZHU Xinggong KONG Yongjin WANG Jianghu LAN Hai CHENG Chengwei XIA Yi LI | 2023 | Science China Earth Sciences2023，66，1： | 0 |
| 8 | Decision Making as Theorem Proving显示文摘We present a method for using type theory to solve decision making problem. Our method is based on the view that decision making is a special kind of theorem proving activity. An isomorphism between problems and types, and solutions and programs has been established to support this view which is much similar to the Curry-Howard isomorphism between propositions and types, and proofs and programs. To support our method, a proof development system called PowerEpsilon has been developed, and the synthesis of a decision procedure for validity of first-order prepositional logic is discussed to show the power of the system. | Zhu, Mingyuan Wang, Chengwei | 1993 | Journal of Systems Engineering and Electronics1993，4，1： | 0 |
| 9 | An experimental study of a single-piston free piston linear generator显示文摘Free piston linear generator(FPLG)is a promising range extender for the electrical vehicle with unparallel advantages,such as compact structure,higher system efficiency,and reduced maintenance cost.However,due to the lack of the mechanic crankshaft,the related piston motion control is a challenge for the FPLG which causes problems such as misfire and crash and limits its widespread commercialization.Aimed at resolving the problems as misfire,a single-piston FPLG prototype has been designed and manufactured at Shanghai Jiao Tong University(SJTU).In this paper,the development process and experimental validation of the related control strategies were detailed.From the experimental studies,significant misfires were observed at first,while the FPLG operated in natural-aspiration conditions.The root cause of this misfire was then identified as the poor scavenging process,and a compressed air source was leveraged to enhance the related scavenging pressure.Afterward,optimal control parameters,in terms of scavenging pressure,air-fuel equivalence ratio,and ignition position,were then calibrated in this charged-scavenging condition.Eventually,the FPLG prototype has achieved a continuous stable operation of over 1000 cycles with an ignition rate of 100%and a cycle-to-cycle variation of less than 0.8%,produced an indicated power of 2.8 kW with an indicated thermal efficiency of 26%and an electrical power of 2.5 kW with an overall efficiency of 23.2%. | Jin XIAO Yingdong CHENG Jinlong WANG Chengwei ZHU Zhen HUANG | 2022 | Frontiers in Energy2022，16，6： | 0 |
| 10 | Norditerpenoids biosynthesized by variediene synthase-associated P450 machinery along with modifications by the host cell Aspergillus oryzae显示文摘The chemical diversity of terpenoids is typically established by terpene synthase-catalyzed cyclization and diversified by post-tailoring modifications.Fungal bifunctional terpene synthase(BFTS)associated P450 enzymes have shown significant catalytic potentials through the development of various new terpenoids with different biological activities.This study discovered the BFTS and its related gene cluster from the plant endophytic fungus Didymosphaeria variabile 17020.Heterologous expression of the BFTS in Saccharomyces cerevisiae resulted in the characterization of a major product diterpene variediene(1),along with two new minor products neovariediene and neoflexibilene.Further heterologous expression of the BFTS and one cytochrome P450 enzyme VndE(CYP6138B1)in Aspergillus oryzae NSAR1 led to the identification of seven norditerpenoids(19 carbons)with a structurally unique 5/5 bicyclic ring system.Interestingly,in vivo experiments suggested that the cyclized terpene variediene(1)was modified by VndE along with the endogenous enzymes from the host cell A.oryzae through serial chemical conversions,followed by multi-site hydroxylation via A.oryzae endogenous enzymes.Our work revealed that the two-enzymes biosynthetic system and host cell machinery could produce structurally unique terpenoids. | Lan Jiang Kangjie Lv Guoliang Zhu Zhi Lin Xue Zhang Cuiping Xing Huanting Yang Weiyan Zhang Zhixin Wang Chengwei Liu Xudong Qu Tom Hsiang Lixin Zhang Xueting Liu | 2022 | Synthetic and Systems Biotechnology2022，7，4： | 0 |
| 11 | NDRG1 promotes endothelial dysfunction and hypoxia-induced pulmonary hypertension by targeting TAF15显示文摘Background:Pulmonary hypertension(PH)represents a threatening pathophysiologic state that can be induced by chronic hypoxia and is characterized by extensive vascular remodeling.However,the mechanism underlying hypoxia-induced vascular remodeling is not fully elucidated.Methods and Results:By using quantitative polymerase chain reactions,western blotting,and immunohistochemistry,we demon-strate that the expression of N-myc downstream regulated gene-1(NDRG1)is markedly increased in hypoxia-stimulated endothelial cells in a time-dependent manner as well as in human and rat endothelium lesions.To determine the role of NDRG1 in endothelial dysfunction,we performed loss-of-function studies using NDRG1 short hairpin RNAs and NDRG1 over-expression plasmids.In vitro,silencing NDRG1 attenuated proliferation,migration,and tube formation of human pulmonary artery endothelial cells(HPAECs)un-der hypoxia,while NDRG1 over-expression promoted these behaviors of HPAECs.Mechanistically,NDRG1 can directly interact with TATA-box binding protein associated factor 15(TAF15)and promote its nuclear localization.Knockdown of TAF15 abrogated the effect of NDRG1 on the proliferation,migration and tube formation capacity of HPAECs.Bioinformatics studies found that TAF15 was involved in regulating PI3K-Akt,p53,and hypoxia-inducible factor 1(HIF-1)signaling pathways,which have been proved to be PH-related pathways.In addition,vascular remodeling and right ventricular hypertrophy induced by hypoxia were markedly alleviated in NDRG1 knock-down rats compared with their wild-type littermates.Conclusions:Taken together,our results indicate that hypoxia-induced upregulation of NDRG1 contributes to endothelial dysfunction through targeting TAF15,which ultimately contributes to the development of hypoxia-induced PH. | Chengwei Li Junzhu Lv Gulinuer Wumaier Yu Zhao Liang Dong Yuzhen Zeng Ning Zhu Xiujuan Zhang Jing Wang Jingwen Xia Shengqing Li | 2023 | Precision Clinical Medicine2023，6，4： | 0 |
| 12 | Review of advanced road materials, structures, equipment, and detection technologies显示文摘As a vital and integral component of transportation infrastructure,pavement has a direct and tangible impact on socio-economic sustainability.In recent years,an influx of groundbreaking and state-of-the-art materials,structures,equipment,and detection technologies related to road engineering have continually and progressively emerged,reshaping the landscape of pavement systems.There is a pressing and growing need for a timely summarization of the current research status and a clear identification of future research directions in these advanced and evolving technologies.Therefore,Journal of Road Engineering has undertaken the significant initiative of introducing a comprehensive review paper with the overarching theme of“advanced road materials,structures,equipment,and detection technologies”.This extensive and insightful review meticulously gathers and synthesizes research findings from 39 distinguished scholars,all of whom are affiliated with 19 renowned universities or research institutions specializing in the diverse and multidimensional field of highway engineering.It covers the current state and anticipates future development directions in the four major and interconnected domains of road engineering:advanced road materials,advanced road structures and performance evaluation,advanced road construction equipment and technology,and advanced road detection and assessment technologies. | JRE Editorial Office Maria Chiara Cavalli De Chen Qian Chen Yu Chen Augusto Cannone Falchetto Mingjing Fang Hairong Gu Zhenqiang Han Zijian He Jing Hu Yue Huang Wei Jiang Xuan Li Chaochao Liu Pengfei Liu Quantao Liu Guoyang Lu Yuan Ma Lily Poulikakos Jinsong Qian Aimin Sha Liyan Shan Zheng Tong B.Shane Underwood Chao Wang Chaohui Wang Di Wang Haopeng Wang Xuebin Wang Chengwei Xing Xinxin Xu Min Ye Huanan Yu Huayang Yu Zhe Zeng You Zhan Fan Zhang Henglong Zhang Wenfeng Zhu | 2023 | Journal of Road Engineering2023，3，4： | 0 |
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