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| 1 | Stable classi?cation with limited sample: transferring a 30-m resolution sample set collected in 2015 to mapping 10-m resolution global land cover in 2017显示文摘As the world strives to reduce the impact of population growth, urbanization, agricultural expansion, and climate change on food security, energy and water shortage, resource over-exploration, biodiversity loss, environmental pollution, and ultimately human health, timely and higher resolution land cover information is urgently needed to achieve the sustainable development goals of the United Nations. | Peng Gong Han Liu Meinan Zhang Congcong Li Jie Wang Huabing Huang Nicholas Clinton Luyan Ji Wenyu Li Yuqi Bai Bin Chen Bing Xu Zhiliang Zhu Cui Yuan Hoi Ping Suen Jing Guo Nan Xu Weijia Li Yuanyuan Zhao Jun Yang Chaoqing Yu Xi Wang Haohuan Fu Le Yu Iryna Dronova Fengming Hui Xiao Cheng Xueli Shi Fengjin Xiao Qiufeng Liu Lianchun Song | 2019 | Science Bulletin2019，64，6： | 166 |
| 2 | Mapping wetland changes in China between 1978 and 2008显示文摘Four wetland maps for all China have been produced,based on Landsat and CBERS-02B remote sensing data between 1978 and 2008 (1978,1990,2000 and 2008).These maps were mainly developed by manual interpretation and validated by substantial field investigation in 2009.Based on these maps,we analyzed the 2008 wetland distribution in China and discussed wetland changes and their drivers over the past 30 years.(i) There were about 324097 km 2 of wetlands in 2008,for which inland marshes or swamps were the most common wetland type (35%),with lakes (26%) second.Most of the wetlands were in Heilongjiang,Inner Mongolia,Qinghai and Tibet,occupying about 55% of the national wetland area.(ii) From 1978 to 2008,China's wetland area continually and significantly decreased,by about 33% based on changes in the wetland map.This was in sharp contrast to the increase in artificial wetlands,which increased by about 122%.Inland marshes accounted for the main loss of total wetlands from 1978 to 2000.From 2000 through 2008,riverine and lacustrine wetlands constituted the main wetland loss.Fortunately however,the rate of wetland loss decreased from 5523 to 831 km 2 /a.(iii) The change ratio of lost natural wetlands (including inland and coastal wetlands) to non-wetlands has decreased slightly over the past 30 years.From 1978 to 1990,nearly all natural wetlands (98%) lost were transformed into non-wetlands.However,the ratio declined to 86% from 1990 to 2000,and to 77% from 2000 to 2008.(iv) All Chinese provinces were divided into three groups according to patterns of wetland changes,which could relate to the driving forces of such changes.Tibet was completely different from other provinces,as it was one representative example in which there was a net wetland increase,because of global warming and decreased human activity since 1990.Increased economic development caused considerable wetland loss in most eastern provinces,and artificial wetlands increased. | NIU ZhenGuo ZHANG HaiYing WANG XianWei YAO WenBo ZHOU DeMin ZHAO KuiYi ZHAO Hui LI NaNa HUANG HuaBing LI CongCong YANG Jun LIU CaiXia LIU Shuang WANG Lin LI Zhan YANG ZhenZhong QIAO Fei ZHENG YaoMin CHEN YanLei SHENG YongWei GAO XiaoHong ZHU WeiHong WANG WenQing WANG Hong WENG YongLing ZHUANG DaFang LIU JiYuan LUO ZhiCai CHENG Xiao GUO ZiQi GONG Peng | 2012 | Chinese Science Bulletin2012，57，22： | 51 |
| 3 | The first all-season sample set for mapping global land cover with Landsat-8 data显示文摘We report the world's first all-season training and validation sample sets for global land cover classification with Landsat-8 data.Prior to this,such samples were only available at a single date primarily from the growing season.It is unknown how much limitation such a single-date sample has to mapping global land cover in other seasons of the year.To answer this question,we selected available Landsat-8 images from four seasons and collected training and validation samples from them.We compared the performances of training samples in different seasons using Random Forest algorithm.We found that the use of training samples from any individual season would result in the best overall classification accuracy when validated by samples in the same season.The global overall accuracy from combined best seasonal results was 67.2% when classifying the 11 Level-1 classes in the Finer Resolution Observation and Monitoring of Global Land Cover(FROM-GLC) classification system.The use of training samples from all seasons(named all-season training sample set hereafter) produced an overall accuracy of 67.0%.We also tested classification within 10° latitude 60° longitude zones using all-season training subsample within each zone and obtained an overall accuracy of 70.2%.This indicates that properly grouped subsamples in space can help improve classification accuracies.All the results in this study seem to suggest that it is possible to use an all-season training sample set to reach global optimality with universal applicability in classifying images acquired at any time of a year for global land cover mapping. | Congcong Li Peng Gong Jie Wang Zhiliang Zhu Gregory S. Biging Cui Yuan Tengyun Hu Haiying Zhang Qi Wang Xuecao Li Xiaoxuan Liu Yidi Xu Jing Guo Caixia Liu Kwame O. Hackman Meinan Zhang Yuqi Cheng Le Yu Jun Yang Huabing Huang Nicholas Clinton | 2017 | Science Bulletin2017，62，7： | 21 |
| 4 | Litter decomposition and C and N dynamics as affected by N additions in a semi-arid temperate steppe, Inner Mongolia of China显示文摘Litter decomposition is the fundamental process in nutrient cycling and soil carbon(C) sequestration in terrestrial ecosystems. The global-wide increase in nitrogen(N) inputs is expected to alter litter decomposition and,ultimately, affect ecosystem C storage and nutrient status. Temperate grassland ecosystems in China are usually N-deficient and particularly sensitive to the changes in exogenous N additions. In this paper, we conducted a 1,200-day in situ experiment in a typical semi-arid temperate steppe in Inner Mongolia to investigate the litter decomposition as well as the dynamics of litter C and N concentrations under three N addition levels(low N with 50 kg N/(hm2?a)(LN), medium N with 100 kg N/(hm2?a)(MN), and high N with 200 kg N/(hm2?a)(HN)) and three N addition forms(ammonium-N-based with 100 kg N/(hm2?a) as ammonium sulfate(AS), nitrate-N-based with 100 kg N/(hm2?a) as sodium nitrate(SN), and mixed-N-based with 100 kg N/(hm2?a) as calcium ammonium nitrate(CAN)) compared to control with no N addition(CK). The results indicated that the litter mass remaining in all N treatments exhibited a similar decomposition pattern: fast decomposition within the initial 120 days, followed by a relatively slow decomposition in the remaining observation period(120–1,200 days). The decomposition pattern in each treatment was fitted well in two split-phase models, namely, a single exponential decay model in phase I(<398 days) and a linear decay function in phase II(≥398 days). The three N addition levels exerted insignificant effects on litter decomposition in the early stages(<398 days, phase I; P>0.05). However, MN and HN treatments inhibited litter mass loss after 398 and 746 days, respectively(P<0.05). AS and SN treatments exerted similar effects on litter mass remaining during the entire decomposition period(P>0.05). The effects of these two N addition forms differed greatly from those of CAN after 746 and 1,053 days, respectively(P<0.05). During the decomposition period, N concentrations in the decomposing litter increased whereas C concentrations decreased, which also led to an exponential decrease in litter C:N ratios in all treatments. No significant effects were induced by N addition levels and forms on litter C and N concentrations(P>0.05). Our results indicated that exogenous N additions could exhibit neutral or inhibitory effects on litter decomposition, and the inhibitory effects of N additions on litter decomposition in the final decay stages are not caused by the changes in the chemical qualities of the litter, such as endogenous N and C concentrations. These results will provide an important data basis for the simulation and prediction of C cycle processes in future N-deposition scenarios. | Qin PENG YuChun QI YunShe DONG YaTing HE ShengSheng XIAO XinChao LIU LiangJie SUN JunQiang JIA ShuFang GUO CongCong CAO | 2014 | Journal of Arid Land2014，6，4： | 16 |
| 5 | Photo-controlled release of paclitaxel and model drugs from RNA pyramids显示文摘Stimuli-resp on sive release of drugs from a nano carrier in spatial-,temporal-,and dosage-controlled fashi ons is of great interest in the pharmaceutical industry.Paclitaxel is one of the most effective and popular chemotherapeutic drugs against a number of cancers such as metastatic or non metastatic breast can cer,non-small cell lung can cer,refractory ovaria n cancer,AIDS-related Kaposi's sarcoma,and head and neck can cers.Here,by taki ng the adva ntage of RNA nanotechno logy in biomedical and material scie nee,we developed a three-dime nsional pyramid-shaped RNA nanocage for a photocontrolled release of cargo,using paclitaxel as a model drug.The light-triggered release of paclitaxel or fluorophore Cy5 was achieved by incorporation of photocleavable spacers into the RNA nanoparticles.Upon irradiation with ultraviolet light,cargos were rapidly released(within 5 min).In vitro treatment of breast can cer cells with the RNA nano particles harbori ng photocleavable paclitaxel showed higher cytotoxicity as compared to RNA nanoparticles without the photocleavable spacer.The methodology provides proof of con cept for the applicati on of the light-triggered con trolled release of drugs from RNA nano cages. | Congcong Xu Hui Li Kaiming Zhang Daniel W.Binzel Hongran Yin Wah Chiu Peixuan Guo | 2019 | Nano Research2019，12，1： | 3 |
| 6 | Association of assisted reproductive technology, germline de novo mutations and congenital heart defects in a prospective birth cohort study显示文摘Emerging evidence suggests that children conceived through assisted reproductive technology(ART)have a higher risk of congenital heart defects(CHDs)even when there is no family history.De novo mutation(DNM)is a well-known cause of sporadic congenital diseases;however,whether ART procedures increase the number of germline DNM(gDNM)has not yet been well studied.Here,we performed whole-genome sequencing of 1137 individuals from 160 families conceived through ART and 205 families conceived spontaneously.Children conceived via ART carried 4.59 more gDNMs than children conceived spontaneously,including 332 paternal and 1.26 maternal DNMs,after correcting for parental age at conception,cigarette smoking,alcohol drinking,and exercise behaviors.Paternal DNMs in offspring conceived via ART are characterized by C>T substitutions at CpG sites,which potentially affect protein-coding genes and are significantly associated with the increased risk of CHD.In addition,the accumulation of non-coding functional mutations was independently associated with CHD and 87.9% of the mutations were originated from the father.Among ART offspring,infertility of the father was associated with elevated paternal DNMs;usage of both recombinant and urinary follicle-stimulating hormone and high-dosage human chorionic gonadotropin trigger was associated with an increase of maternal DNMs.In sum,the increased gDNMs in offspring conceived by ART were primarily originated from fathers,indicating that ART itself may not be a major reason for the accumulation of gDNMs.Our findings emphasize the importance of evaluating the germline status of the fathers in families with the use of ART. | Cheng Wang Hong Lv Xiufeng Ling Hong Li Feiyang Diao Juncheng Dai Jiangbo Du Ting Chen Qi Xi Yang Zhao Kun Zhou Bo Xu Xiumei Han Xiaoyu Liu Meijuan Peng Congcong Chen Shiyao Tao Lei Huang Cong Liu Mingyang Wen Yangqian Jiang Tao Jiang Chuncheng Lu Wei Wu Di Wu Minjian Chen Yuan Lin Xuejiang Guo Ran Huo Jiayin Liu Hongxia Ma Guangfu Jin Yankai Xia Jiahao Sha Hongbing Shen Zhibin Hu | 2021 | Cell Research2021，31，8： | 2 |
| 7 | Effects of typhoon Roke and Haitang on phytoplankton community structure in northeastern South China sea显示文摘The influence of typhoon and Kuroshio intrusion process on the natural phytoplankton assemblages in the northeastern South China Sea(neSCS)was examined during a cruise in summer 2017.One hundred ninety-six seawater samples were collected and analyzed in the neSCS.In total,299 species were identified belonging to 82 genera,mostly dominated by Bacillariophyta(159),followed by Dinophyta(132),Cyanophyta(4)and Chrysophyta(4).Among all,Thalassionema nitzschioides,Thalassionema frauenfeldii,Thalassiosira minima,in Bacillariophyta,Prorocentrum lenticulatum,Prorocentrum compressum in Dinophyta,and Trichodesmium thiebautii,in the Cyanophyta were the most dominated species,respectively.Correlation analysis shows compared with other groups Bacillariophyta was mostly influenced by silicate,whereas,Dinophyta and Cyanophyta showed significant correlation with temperature,salinity,phosphate,and nitrate.After the typhoon,the higher abundance of Dinophyta was observed,whereas it was lower in case of Bacillariophyta and Cyanophyta,shows typhoon“Roke“and”Haitang”had a significant influence on the phytoplankton assemblages,which could be manifested by the variations of total phytoplankton abundance in the surface water of neSCS.Overall,our present study provides the latest in-depth information about how the environmental factors influencing the phytoplankton density and diversity in the neSCS during summer. | Yingjie Mao Jun Sun Congcong Guo Yuqiu Wei Xingzhou Wang Shuang Yang Chao Wu | 2019 | Ecosystem Health and Sustainability2019，5，1： | 2 |
| 8 | Integration of preparation of K,Na-embedded activated carbon and reduction of Zn-bearing dusts显示文摘Large amounts of solid wastes and flue gases are generated in iron and steel production process,probably leading to serious environmental pollution without duly handle.An innovative and green process of simultaneous reduction of zinc-bearing dusts and activation of low-rank coal was developed and its mechanism was clarified in this paper.Under the optimal conditions,the reduced zinc-bearing dusts containing low harmful elements(0.02%Zn,0.015%K and 0.03%Na)could be made as high-quality burden for blast furnace while the low-rank coal was transferred into K,Na-embedded activated carbon,which can be used as effective adsorbent for purification of SO_(2) and NO-containing flue gases.The solid wastes were successfully utilized to treat the flue gases through the process.The synergetic activation and reduction mechanism in the process was revealed.The coupling effect between reduction reactions of metal oxides in the dusts and activation reaction of carbon in the coal promoted the simultaneous reduction and activation process.In the meanwhile,part of the potassium and sodium from the zinc-bearing dusts could be adsorbed by the activated carbon and played a catalytic role in the activation process. | Dingzheng Wang Deqing Zhu Jian Pan Zhengqi Guo Congcong Yang Hongyu Tian Yuxiao Xue | 2022 | International Journal of Mining Science and Technology2022，32，3： | 1 |
| 9 | A haplotype map of genomic variations and genome-wide association studies of agronomic traits in foxtail millet(Setaria italica)显示文摘 | Guanqing Jia Xuehui Huang Hui Zhi Yan Zhao QiangZhao Wenjun Li Yang Chai Lifang Yang Kunyan Liu Hengyun Lu Chuanrang Zhu Yiqi Lu Congcong Zhou Danlin Fan Qijun Weng Yunli Guo Tao Huang LeiZhang Tingting Lu Qi Feng Hangfei Hao HongkuanLiu Ping Lu Ning Zhang Yuhui Li Erhu Guo ShujunWang Suying Wang Jinrong Liu Wenfei Zhang GuoqiuChen Baojin Zhang Wei Li Yongfang Wang HaiquanLi Baohua Zhao Jiayang Li Xianmin Diao Bin HanJia | 2013 | Nature Genetics2013，45，8： | 1 |
| 10 | A complete assembly of the rice Nipponbare reference genome显示文摘Dear Editor,In 2005,the current commonly used rice reference genome(Oryza sativa ssp.japonica cv.Nipponbare)was initially released by the International Rice Genome Sequencing Project(International Rice Genome Sequencing Project,2005).Thereafter,the reference genome was further updated in 2013 with improved genome assembly(IRGSP-1.0)and gene annotations(MSU7,RAP-DB)(Kawahara et al.,2013;Sakai et al.,2013).In the past 10 years,this reference has been serving as one of the most important genetic resources for subsequent rice functional genomics efforts.As several rice genomes had been assembled into gapless chromosomes with only 2–5 telomeres absent(Li et al.,2021;Song et al.,2021;Zhang et al.,2022),the IRGSP1.0 and its annotations still performed as the most widely used reference.However,limitations of sequencing technology and intricate genomic organization led to an under-representation of complex regions in this reference,leaving a total of 72 major gaps(including 19 telomeres),167 minor gaps,and 779 unknown bases(Kawahara et al.,2013),with an estimated length of3%of the genome unsolved. | Lianguang Shang Wenchuang He Tianyi Wang Yingxue Yang Qiang Xu Xianjia Zhao Longbo Yang Hong Zhang Xiaoxia Li Yang Lv Wu Chen Shuo Cao Xianmeng Wang Bin Zhang Xiangpei Liu Xiaoman Yu Huiying He Hua Wei Yue Leng Chuanlin Shi Mingliang Guo Zhipeng Zhang Bintao Zhang Qiaoling Yuan Hongge Qian Xinglan Cao Yan Cui Qianqian Zhang Xiaofan Dai Congcong Liu Longbiao Guo Yongfeng Zhou Xiaoming Zheng Jue Ruan Zhukuan Cheng Weihua Pan Qian Qian | 2023 | Molecular Plant2023，16，8： | 1 |
| 11 | Processing micrometer-sized particles in crumpled graphene network for freestanding membrane enabled by freeze casting显示文摘Graphene oxide(GO)is widely used in the construction and application of various 2 D membrane-based materials due to its unique colloidal structure.Herein,we demonstrate that micrometer-sized particles can make up freestanding membranes enabled by the extraordinary amphiphilic and polymer-like properties of graphene oxide through freeze casting.The 2 D macromolecule,GO could well wrap the particles for better uniformity and stability in either dispersion or membrane.Importantly,freeze casting plays an important role in avoiding the severe aggregation of micrometer-sized particles in the solventremoving process.After reduction,the membrane exhibits good electrical conductivity while maintaining its integral structure,which can be directly used as a freestanding binder-free electrode.This work provides a universal approach to fabricate freestanding membranes with various micrometersized materials for energy storage. | Jing Cao Xiaoli Zhao Jiahe Wang Huanglin Dou Congcong Liu Xiaojun Yan Yuantao Yan Min Guo Wanyu Zhao Xiaowei Yang | 2020 | Chinese Chemical Letters2020，31，1： | 1 |
| 12 | Distribution and environmental impact factors of picophytoplankton in the East China Sea during spring显示文摘Marine picophytoplankton(Pico)as a major contributor to primary productivity in oligotrophic waters,play a very important role in marine material cycle and energy conversion,and their key role in the carbon cycle and global climate change is increasingly emphasized.To study the factors aff ecting the dynamic distribution of Synechococcus,Prochlorococcus,and picoeukaryotes in the East China Sea(ECS),a marginal sea of the Northwest Pacific,we investigated 27 stations in May 2017,and collected 148 samples of Pico and nutrients from the surface to the bottom.By means of flow cytometry,the abundance of Pico was measured,and then we estimated the carbon biomass and analyzed the distribution of Pico.Finally,combined with the ECS unique geographical situation and hydrological regime,we evaluated various factors aff ecting the Pico in the ECS.In Pico community,the picoeukaryotes cell abundance was between 0.49×10^(2)-1.44×10^(4) cells/mL.Prochlorococcus ranged from 1.36×10^(3)-3.47×10^(4) cells/mL and Synechococcus ranged from 0.69×10^(3)-1.15×105 cells/mL.Synechococcus was the most,both in abundance and in carbon biomass.Picoeukaryotes were the least in abundance,but has larger contribution to carbon biomass than Prochlorococcus.Water temperature,salinity,and stability of water column influenced Pico distribution.Picoeukaryotes were abundant in the shelf sea,whereas Synechococcus and Prochlorococcus were detected in the northeast of Taiwan,China.This study provided basic information for the study of Pico communities in the ECS and its adjacent marine ecosystem. | Feng WANG Yuqiu WEI Jiaqi YUE Congcong GUO Jun SUN | 2021 | Journal of Oceanology and Limnology2021，39，4： | 1 |
| 13 | The profound influence of Kuroshio intrusion on microphytoplankton community in the northeastern South China Sea显示文摘To further understand the effect of Kuroshio intrusion on phytoplankton community structure in the northeastern South China Sea(NSCS,14°–23°N,114°–124°E),one targeted cruise was carried out from July to August,2017.A total of 79 genera and 287 species were identified,mainly including Bacillariophyta(129 species),Pyrrophyta(150 species),Cyanophyta(4 species),Chrysophyta(3 species)and Haptophyta(1 species).The average abundance of phytoplankton was 2.14×10~3 cells/L,and Cyanobacterium was dominant species accounting for 86.84%of total phytoplankton abundance.The abundance and distribution of dominant Cyanobacterium were obviously various along the flow of the Kuroshio,indicating the Cyanobacterium was profoundly influenced by the physical process of the Kuroshio.Therefore,Cyanobacterium could be used to indicate the influence of Kuroshio intrusion.In addition,the key controlling factors of the phytoplankton community were nitrogen,silicate,phosphate and temperature,according to Canonical Correspondence Analysis.However,the variability of these chemical parameters in the study water was similarly induced by the physical process of circulations.Based on the cluster analysis,the similarity of phytoplankton community is surprisingly divided by the regional influence of the Kuroshio intrusion,which indicated Kuroshio intrusion regulates phytoplankton community in the NSCS. | Xingzhou Wang Yuqiu Wei Chao Wu Congcong Guo Jun Sun | 2020 | Acta Oceanologica Sinica2020，39，8： | 1 |
| 14 | Natural incidence of Fusarium species and fumonisins B1 and B2 associated with maize kernels from nine provinces in China in 2012显示文摘 | Meng Fu Renjie Li Congcong Guo Minhao Pang Yingchao Liu Jingao Dong | 2015 | Food Additives & Contaminants: Part A2015，，4： | 1 |
| 15 | Pre-protective effect of lipoic acid on injury induced by H 2 O 2 in IPEC-J2 cells显示文摘 | Xuan Cai Xiaolian Chen Xiaochun Wang Congcong Xu Qi Guo Lihui Zhu Shuwen Zhu Jianxiong Xu | 2013 | Molecular and Cellular Biochemistry2013，，1： | 1 |
| 16 | Effects of water and nitrogen addition on vegetation carbon pools in a semi-arid temperate steppe显示文摘Global change will lead to increases in regional precipitation and nitrogen(N) deposition in the semi-arid grasslands of northern China. We investigated the responses of vegetation carbon(C) pools to simulated precipitation and N deposition increases through field experiments in a typical steppe in Inner Mongolia. The treatments included NH_4NO_3 addition at concentrations of 0(CK), 5(LN, low nitrogen), 10(middle nitrogen, MN), and 20(HN,high nitrogen)(g m^(-2)a^(-1)) with and without water. After three consecutive years of treatment, from 2010 to 2012,water addition did not significantly change the size of the total vegetation C pools, but it significantly decreased the ratio of root:shoot(R:S)(P = 0.05) relative to controls. By contrast, N addition significantly increased the total vegetation C pools. The C pools in the LN, MN and HN treatments increased by 22, 39 and 44 %, respectively. MN produced the largest effect among the N concentrations,although differences between N-added treatments were not significant(P [ 0.05). N addition significantly reduced the ratio of root:shoot(R:S)(P = 0.03). However, there were no significant interactive effects of water and N addition on the vegetation C pools. | Junqiang Jia Yunshe Dong Yuchun Qi Qin Peng Xinchao Liu Liangjie Sun Shufang Guo Yunlong He Congcong Cao Zhongqing Yan | 2016 | Journal of Forestry Research2016，27，3： | 1 |
| 17 | Phytoplankton growth and microzooplankton grazing in the central and northern South China Sea in the spring intermonsoon season of 2017显示文摘Phytoplankton growth rates and mortality rates were experimentally examined at 21 stations during the 2017 spring intermonsoon(April to early May)in the northern and central South China Sea(SCS)using the dilution technique,with emphasis on a comparison between the northern and central SCS areas which had different environmental factors.There had been higher temperature but lower nutrients and chlorophyll a concentrations in the central SCS than those in the northern SCS.The mean rates of phytoplankton growth(μ0)and microzooplankton grazing(m)were(0.88±0.33)d–1 and(0.55±0.22)d–1 in the central SCS,and both higher than those in the northern SCS with the values ofμ0((0.81±0.16)d–1)and m((0.30±0.09)d–1),respectively.Phytoplankton growth and microzooplankton grazing rates were significantly coupled in both areas.The microzooplankton grazing impact(m/μ0)on phytoplankton was also higher in the central SCS(0.63±0.12)than that in the northern SCS(0.37±0.06).The microzooplankton abundance was significantly correlated with temperature in the surface.Temperature might more effectively promote the microzooplankton grazing rate than phytoplankton growth rate,which might contribute to higher m and m/μ0 in the central SCS.Compared with temperature,nutrients mainly affected the growth rate of phytoplankton.In the nutrient enrichment treatment,the phytoplankton growth rate(μn)was higher thanμ0 in the central SCS,suggesting phytoplankton growth in the central SCS was nutrient limited.The ratio ofμ0/μn was significantly correlated with nutrients concentrations in the both areas,indicating the limitation of nutrients was related to the concentrations of background nutrients in the study stations. | Dawei Chen Congcong Guo Linhui Yu Yuanzhen Lu Jun Sun | 2020 | Acta Oceanologica Sinica2020，39，6： | 0 |
| 18 | Role of the Volatile Components in the Anti-insomnia Effect of Jiao-Tai-Wan in PCPA-induced Insomnia Rats显示文摘Background:Jiao-Tai-Wan(JTW)is widely used for insomnia in traditional Chinese medicine.It has been found that berberine in JTW has a potential anti-insomnia effect,but the anti-insomnia effect of volatile oil,which is another major component in JTW,remains unclear.Objective:To comprehensively analyze the anti-insomnia effect of volatile oil through chemical analysis,phar-macological research and network pharmacology methods.Methods:Gas chromatography-mass spectrometry(GC-MS)analysis and network pharmacology platform were used to elucidate the material basis,effect and mechanism of JTW in the treatment of insomnia.A rat model of insomnia induced by p-Chlorophenylalanine(PCPA)was used to verify its anti-insomnia effect.The levels of Melatonin(MT)and Melatonin receptor type 1b(MTNR1B)in the brain and serum of rats were detected by ELISA,Western blot and Real-time PCR methods.Results:Eighteen volatile oil ingredients of JTW were identified by GC-MS,containing six new components which were found in JTW for the first time.Cinnamaldehyde,Behenic alcohol,Tetradecanal,and Gleenol can promote sleep by targeting MTNR1B according to the predicted results of network-pharmacology.Compared with the model group,JTW can increase the level of MTNR1B in rats’prefrontal cortex and brain stem,while reducing the level of MT in rats’brain stem.Conclusion:The volatile oil components,such as Cinnamaldehyde,Tetradecanal,and Gleenol,might also be playing a critical role in the anti-insomnia effect of JTW by target MTNR1B. | Xi Liu Zhengzhong Yuan Congcong Zeng Yan Huang Xie Xu Wenqin Guo Hongbin Zheng Ruanjuan Zhan | 2022 | Clinical Complementary Medicine and Pharmacology2022，2，1： | 0 |
| 19 | The sensitivity of numerical simulation to vertical mixing parameterization schemes: a case study for the Yellow Sea Cold Water Mass显示文摘The vertical mixing parameterization scheme,by providing the eff ects of some explicitly missed physical processes and more importantly closing the energy budgets,is a critical model component and therefore imposes signifi cant impacts on model performance.The Yellow Sea Cold Water Mass(YSCWM),as the most striking and unique phenomenon in the Yellow Sea during summer,is dramatically aff ected by vertical mixing process during its each stage and therefore seriously sensitive to the proper choice of parameterization scheme.In this paper,a hindcast of YSCWM in winter of 2006 was implemented by using the Regional Ocean Modeling System(ROMS).Three popular parameterization schemes,including the level 2.5 Mellor-Yamada closure(M-Y 2.5),Generic Length Scale closure(GLS)and K-Profi le Parameterization(KPP),were tested and compared with each other by conducting a series of sensitivity model experiments.The infl uence of diff erent parameterization schemes on modeling the YSCWM was then carefully examined and assessed based on these model experiments.Although reasonable thermal structure and its seasonal variation were well reproduced by all schemes,considerable diff erences could still be found among all experiments.A warmer and spatially smaller simulation of YSCWM,with very strong thermocline,appeared in M-Y 2.5 experiment,while a spatially larger YSCWM with shallow mixed layer was found in GLS and KPP schemes.Among all the experiments,the discrepancy,indicated by core temperature,appeared since spring,and grew gradually by the end of November.Additional experiments also confi rmed that the increase of background diff usivity could eff ectively weaken the YSCWM,in either strength or coverage.Surface wave,another contributor in upper layer,was found responsible for the shrinkage of YSCWM coverage.The treatment of wave eff ect as an additional turbulence production term in prognostic equation was shown to be more superior to the strategy of directly increasing diff usivity for a coastal region. | Congcong BI Zhigang YAO Xianwen BAO Cong ZHANG Yang DING Xihui LIU Junru GUO | 2021 | Journal of Oceanology and Limnology2021，39，1： | 0 |
| 20 | Discovery of amantadine formate:Toward achieving ultrahigh pyroelectric performances in organics显示文摘Pyroelectrics are a class of polar compounds that output electrical signals upon changes in temperature.With the rapid development of flexible electronics,organic pyroelectrics are highly desired.However,most organics suffer from low pyroelectric coefficients or low working temperatures.To date,the realization of superior pyroelectric performance in all-organics has remained a challenge. | Junyan Zhou Shifeng Jin Congcong Chai Munan Hao Xin Zhong Tianping Ying Jiangang Guo Xiaolong Chen | 2022 | The Innovation2022，3，2： | 0 |
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