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| 1 | Application of nonlinear chemical fingerprinting to identification,evaluation and clinical use of Glycyrrhiza显示文摘Nonlinear chemical fingerprinting is a new technique for analyzing traditional Chinese medicines (TCMs). We developed such a method and applied it to Glycyrrhiza, a significant TCM. Nonlinear chemical fingerprints were obtained for Glycyrrhiza from four different production areas, and for 14 other TCMs with similar induction time. The calculation of their similarities was based on similarity system theory. Using intuitive visual comparison of the data and the similarity calculation results, Glycyrrhiza was discriminated from the 14 other TCMs. There was a linear relationship between the content of active TCM components and the induction time. This was used to compare the content of active components in Glycyrrhiza from the four different production areas, and establish an equivalent-dose relationship for these four samples. This method provides a new tool for discrimination and evaluation of Glycyrrhiza, and a dosage reference for clinical application of Glycyrrhiza from the four regions studied. | FANG XuanQi ZHANG TaiMing ZHAO Zhe XIANG FengQin LIANG YiZeng WANG Mei ZHU Rong CHEN Su QIAO JunXi | 2010 | Chinese Science Bulletin2010，55，26： | 20 |
| 2 | Identification of coastal wetlands of international importance for waterbirds:a review of China Coastal Waterbird Surveys 2005–2013显示文摘Background:China's coastal wetlands belong to some of the most threatened ecosystems worldwide.The loss and degradation of these wetlands seriously threaten waterbirds that depend on wetlands.Methods:The China Coastal Waterbird Census was organized by volunteer birdwatchers in China's coastal region.Waterbirds were surveyed synchronously once every month at 14 sites,as well as irregularly at a further 18 sites,between September 2005 and December 2013.Results:A total of 75 species of waterbirds met the 1 % population level Ramsar listing criterion at least once at one site.The number of birds of the following species accounted for over 20 % of the total flyway populations at a single site:Mute Swan(Cygnus olor),Siberia Crane(Grus leucogeranus),Far Eastern Oystercatcher(Haematopus osculans),Bar-tailed Godwit(Limosa lapponica),Spotted Greenshank(Tringa guttifer),Great Knot(Calidris tenuirostris),Spoon-billed Sandpiper(Calidris pygmeus),Saunders' s Gull(Larus saundersi),Relict Gull(Larus relictus),Great Cormorant(Phalacrocorax carbo),Eurasian Spoonbill(Platalea leucorodia),Black-faced Spoonbill(Platalea minor) and Dalmatian Pelican(Pelecanus crispus).A total of 26 sites supported at least one species of which their number met the1 % criterion.Forty-two species met the 1 % criterion in the Yellow River Delta,Shandong;29 at the Cangzhou coast,Hebei and 26 species at the Lianyungang coast,Jiangsu.Conclusions:The results highlight the international importance of China's coastal wetlands for waterbirds.This study also demonstrates that participation of local birdwatchers in waterbird surveys results in data that are invaluable not only for understanding the current status of waterbirds in China's coastal regions but also for waterbird conservation and management. | Qingquan Bai Jianzhong Chen Zhihong Chen Guotai Dong Jiangtian Dong Wenxiao Dong Vivian Wing Kan Fu Yongxiang Han Gang Lu Jing Li Yang Liu Zhi Lin Derong Meng Jonathan Martinez Guanghui Ni Kai Shan Renjie Sun Suixing Tian Fengqin Wang Zhiwei Xu Yat-tung Yu Jin Yang Zhidong Yang Lin Zhang Ming Zhang Xiangwu Zeng | 2015 | Chinese Birds2015，，3： | 20 |
| 3 | COVID-19 Outbreak Caused by Contaminated Packaging of Imported Cold-Chain Products—Liaoning Province,China,July 2020显示文摘Summary What is known about this topic?Few major outbreaks of coronavirus disease 2019(COVID-19)have occurred in China after major nonpharmaceutical interventions and vaccines have been deployed and implemented.However,sporadic outbreaks that had high possibility to be linked to cold chain products were reported in several cities of China..What is added by this report?In July 2020,a COVID-19 outbreak occurred in Dalian,China.The investigations of this outbreak strongly suggested that the infection source was from COVID-19 virus-contaminated packaging of frozen seafood during inbound unloading personnel contact.What are the implications for public health practice?Virus contaminated paper surfaces could maintain infectivity for at least 17–24 days at-25℃.Exposure to COVID-19 virus-contaminated surfaces is a potential route for introducing the virus to a susceptible population.Countries with no domestic transmission of COVID-19 should consider introducing prevention strategies for both inbound travellers and imported goods.Several measures to prevent the introduction of the virus via cold-chain goods can be implemented. | Huilai Ma1 Jianqun Zhang Ji Wang Ying Qin Cao Chen Yang Song Liang Wang Jun Meng Lingling Mao Fengqin Li Ning Li Jian Cai Yong Zhang Dayan Wang Yunting Xia Hong Wang Shaofeng Jiang Xiang Zhao Peihua Niu Wenjie Tan Tao Ma Yecheng Yao Naiying Mao Zhen Zhu Tianjiao Ji Qian Yang Baoying Huang Li Zhao Jianxing Yu Li Bai Shuangli Zhu Dongyan Wang Yan Zhang Yingwei Sun Mingchun Luan Yanhai Wang Haibo Sun Shihong Yang Zhijian Bo Xiang Ren Zhongjie Li George Fu Gao Wei Yao Wenqing Yao Zijian Feng Wenbo Xu | 2021 | China CDC weekly2021，3，21： | 16 |
| 4 | Determining method,conditional factors,traits and applications of nonlinear chemical fingerprint by using dissipative components in samples显示文摘The thermodynamic systems and dynamic model suitable for determining the nonlinear chemical fingerprints of samples were analyzed.The results indicated that the damp nonlinear chemical reactions in close systems away from the equilibrium and open systems without the complementarity of the dissipation substances have important significance for the throng characterization and whole content analysis of chemical components in samples.Various factors influencing on nonlinear chemical fingerprint,such as reactant species and their concentrations,electrode types,temperature,stir rate,the sort,dosage and granularity of the sample,etc.were amply researched by a nonlinear chemistry reaction,namely,damp B-Z oscillation which used acetone and glucose as the main dissipative substances.In addition,the quantitative information on the whole of chemical components in samples and the traits and applications of the fingerprint were investigated.The method and its important conditions for determining nonlinear chemistry fingerprint used in distinguishing and evaluating complex samples were successfully put forward. | ZHANG TaiMing ZHAO Zhe FANG XuanQi QIAO JunXi XIANG FengQin ZHU Rong LIANG YiZeng DING Feng | 2012 | Science China Chemistry2012，55，2： | 16 |
| 5 | Molecular fossil and paleovegetation records of paleosol S4 and adjacent loess layers in the Luochuan loess section, NW China显示文摘Using gas chromatography-mass spectrometry (GC-MS) technique, a series of biomarkers were identi- fied, including n-alkanes, n-alkane-2-ones, isoprenoid etc. from the loess-paleosol samples collected from the S4 and adjacent L5, L4 of the Luochuan loess section, Northwestern China. Based on these data, especially n-alkanes and high-resolution magnetic susceptibility and grain size data, the pa- leoenvironment and paleovegetation history during S4 was reconstructed. The CPI (Carbon Predomi- nance Index) and correlation between n-alkanes and magnetic susceptibility and grain size data dem- onstrated that the molecular fossils in paleosol and loess layers can reflect the vegetation condition during the loess-paleosol formation, if the allochthonous organic inputs could be excluded reasonably. The ACL (average chain length) index is correlated well with paleomagnetic susceptibility and grain size variations, displaying their good synchrony with warm and humid climate. However, it relatively lagged behind the paleomagnetic susceptibility and the grain size variations when the climate began to deteriorate. During the formation period of paleosol, the n-alkanes was dominated by C31 homologue, indicating that the primary organic input originated from herbs. Our study also demonstrated that the herbs were more flourish than wood plants in Loess Plateau, especially in the Luochuan area during the warm and humid phase, and there was no typical forest vegetation developed in the studied period. | ZHANG HuCai YANG MingSheng ZHANG WenXiang LEI GuoLiang CHANG FengQin PU Yang FAN HongFang | 2008 | Science China Earth Sciences2008，51，3： | 15 |
| 6 | THE LEARNER-CENTERED APPROACH——AN EFFECTIVE WAY TO DEVELOP STUDENTS'COMMUNICATIVE ABILITY显示文摘This paper will first focus on a brief evaluation ofthe teacher-centered and the learner-centered method-ologies.Then,it presents the practical ways of teach-ing based on the learner-centered approach in class-rooms to show how students’initiative is given fullplay.Finally,it presents the guidance from fellowstudents and teachers in group activitis.The purposeof the learner-centered approach is to develop students’communicative | Zhang Fengqin Qiqihar University | 2000 | Chinese Journal of Applied Linguistics2000，23，2： | 15 |
| 7 | Principle of nonlinear chemical fingerprint by using dissipative components in samples as well as calculation and evaluation of similarity显示文摘Under the conditions of constant temperature and pressure,different influences of samples with different chemical components on the mechanism of nonlinear chemical reaction will cause different changes of the potential-time relationship curve of the nonlinear chemical reaction system.Using it as the character,and using the B-Z nonlinear chemical system to use acetone and substrates in samples as main dissipative substances qua an example,the principle of nonlinear chemical fingerprint has been researched and discussed in detail.At the same time,the general method for calculating the system similarity about nonlinear chemical fingerprint was also put forward,and similarities of nonlinear chemistry fingerprints of different batches of Guhan Yangshengjing and 18 sorts of other samples were calculated by Euclidean distance,correlation coefficient,included angle cosine and system similarity,at the same time,the various similarities were analyzed.The results showed that,both of correlation coefficient and included angle cosine are unable to be used as the criterion for quantitatively evaluating the similarity of nonlinear chemistry fingerprint;as non-parametric similarity,Euclidean distance can accurately reflect the feature differences in the fingerprints,but as parametric similarity,sometimes,Euclidean distance can not accurately reflect the relative extent of characteristic difference in the nonlinear chemical fingerprints;system similarity can most truthfully reflect the characteristic difference in the nonlinear chemical fingerprints,and is the best evaluating method among the four ones.Therefore,system similarity can be used to quantitatively calculate the similar extent between the nonlinear chemical fingerprints.An economical,simple and convenient,easy pushing and effective method for identifying and evaluating complicated samples has successfully been put forward. | ZHANG TaiMing ZHAO Zhe FANG XuanQi QIAO JunXi XIANG FengQin ZHU Rong LIANG YiZeng DING Feng | 2012 | Science China Chemistry2012，55，2： | 13 |
| 8 | COVID-19: Challenges to GIS with Big Data显示文摘The outbreak of the 2019 novel coronavirus disease(COVID-19)has caused more than 100,000 people infected and thousands of deaths.Currently,the number of infections and deaths is still increasing rapidly.COVID-19 seriously threatens human health,production,life,social functioning and international relations.In the fight against COVID-19,Geographic Information Systems(GIS)and big data technologies have played an important role in many aspects,including the rapid aggregation of multi-source big data,rapid visualization of epidemic information,spatial tracking of confirmed cases,prediction of regional transmission,spatial segmentation of the epidemic risk and prevention level,balancing and management of the supply and demand of material resources,and socialemotional guidance and panic elimination,which provided solid spatial information support for decision-making,measures formulation,and effectiveness assessment of COVID-19 prevention and control.GIS has developed and matured relatively quickly and has a complete technological route for data preparation,platform construction,model construction,and map production.However,for the struggle against the widespread epidemic,the main challenge is finding strategies to adjust traditional technical methods and improve speed and accuracy of information provision for social management.At the data level,in the era of big data,data no longer come mainly from the government but are gathered from more diverse enterprises.As a result,the use of GIS faces difficulties in data acquisition and the integration of heterogeneous data,which requires governments,businesses,and academic institutions to jointly promote the formulation of relevant policies.At the technical level,spatial analysis methods for big data are in the ascendancy.Currently and for a long time in the future,the development of GIS should be strengthened to form a data-driven system for rapid knowledge acquisition,which signifies ts that GIS should be used to reinforce the social operation parameterization of models and methods,especially when providing support for social management. | Chenghu Zhou Fenzhen Su Tao Pei An Zhang Yunyan Du Bin Luo Zhidong Cao Juanle Wang Wen Yuan Yunqiang Zhu Ci Song Jie Chen Jun Xu Fujia Li Ting Ma Lili Jiang Fengqin Yan Jiawei Yi Yunfeng Hu Yilan Liao Han Xiao | 2020 | Geography and Sustainability2020，1，1： | 13 |
| 9 | Branched aliphatic alkanes of shell bar section in Qarhan Lake,Qaidam Basin and their paleoclimate significance显示文摘Biomarkers of paleolake deposits from Qarhan Salt Lake in Qaidam Basin,northwest China were sys-tematically analyzed and the A―C series compounds of branched aliphatic alkanes with quaternary substituted carbon atom(BAQCs) were identified. The homologous distinguished three series,A―C,were identified as 5,5-diethylalkanes,6,6-diethylalkanes and 5-butyl,5-ethylalkanes series,and their relative abundance was A > B > C. Series A and C were characterized by odd carbon numbers,whereas series B was characterized by even carbon numbers. The high values of series A corresponded with the high values of series B and C. Therefore,it can be concluded that series A,B and C possess a similar biological origin. The abundance of series A was relatively low in the lower part of the section compared with that in the upper part,implying that these series originated from bacteria and/or algae more prevalent in fresh-mesohaline water,and such kinds of bacteria and/or algae are most likely to be thermophilous species. The A25/nC25 ratio differences in the section show that such branched aliphatic alkanes can be treated as one kind of environmental change proxy for paleolake evolution and may provide important information for the climate reconstruction of the Late Pleistocene. | ZHANG HuCai CHANG FengQin LI Bin LEI GuoLiang CHEN Yue ZHANG WenXiang NIU Jie FAN HongFang YANG MingSheng | 2007 | Chinese Science Bulletin2007，52，9： | 13 |
| 10 | Geochemical fractionation of rare earth elements in lacustrine deposits from Qaidam Basin显示文摘Based on the concentration and distribution pattern analysis of the rare earth elements (REEs) at the Shell Bar section from Qaidam Basin, we studied the geochemical fractionations of REE in paleolake deposits and their paleo-environmental significance. Our results show that the REE concentration in AS (acid soluble) and AR (acid residual) fractions are 20.9 μg/g and 95.4 μg/g (except element Y) individually, showing a strong REE differentiation between AS and AR fractions. However, the two types of fractions (AS & AR) have similar REE distribution patterns, which are slightly rich in light earth rare elements (LREEs), with slightly right-tilting and negative Eu anomaly. The LREE of AR is richer than that of AS. There were no significant correlations between the REE in AS, AR and other proxies. It indicated that the lacustrine deposition had different material sources and experienced varying geochemical procedures. Correlation analysis between the REE and the content of fine grain-size (<4 μm) of the sediments, Rb/Sr ratio and Mn concentration showed high correlation coefficients. Our results demonstrated that the REE in acid soluble and residual fractions bear different environmental significances, which are strongly dependent on local environment. The REE of acid soluble fraction is closely related to the paleoclimatic changes in the lake catchment and the evolutionary processes of lake itself. Our results suggest that δCe and (La/Yb)n could be used as proxies of the reduction-oxidation conditions and furthermore the temperature change and the lake level fluctuations. Using these proxies, we reconstructed the paleoclimate and water level fluctuation history during the high lake level period lasting between 43.5 and 22.4 cal. ka BP. | ZHANG HuCai ZHANG WenXiang CHANG FengQin YANG LunQing LEI GuoLiang YANG MingSheng PU Yang LEI YangBin | 2009 | Science China Earth Sciences2009，52，11： | 9 |
| 11 | Climate variability recorded by n-alkanes of paleolake sediment in Qaidam Basin on the northeast Tibetan Plateau in late MIS3显示文摘Here we combine n-alkanes preserved in a shell bar section from Qarhan paleolake, Qaidam Basin with the other sedimentary proxies to elucidate the lake evolution process during the period 39.7 to 17.5 14C ka BP (calibrated age ranges from 43.5 to 22.4 cal. ka BP). In different stages, the n-alkane homologues exhibited different distribution modes indicative of variations in the surrounding vegetation and the hydrologic condition of the lake. The n-alkanes proxies (CPIh, ACLh, Paq) have the same trends as the summer solar insolation variation, implying that the summer insolation is the most important climatic factor driving the environmental changes and also indirectly controls lake evolution on the Tibetan Plateau. CPIh and ACLh as well as the total pollen concentration appear to show a trend comparable with methane concentration record from the GRIP ice core that reflected the Dansgaard-Oeschger events. This demonstrates that the paleoclimate variations in Qarhan area generally agree with global climate change and show rapid oscillations in late MIS3. These findings provide the latest molecular fossil evidence from paleolake sediments to confirm that lake evolution on Tibetan Plateau in late MIS3 was closely associated with enhanced summer insolation. | PU Yang ZHANG HuCai LEI GuoLiang CHANG FengQin YANG MingSheng ZHANG WenXiang LEI YanBin YANG LunQing PANG YouZhi | 2010 | Science China Earth Sciences2010，53，6： | 8 |
| 12 | Kinetics of serum HBsAg in Chinese patients with chronic HBV infection with long-term adefovir dipivoxil treatment显示文摘 | Li Minran Xi Hongli Wang Qinhuan Hou Fengqin Huo Na Zhang Xiaxia Li Fang Xu Xiaoyuan | 2014 | Chinese Medical Journal2014，，11： | 5 |
| 13 | Assessment of High-standard Farmland Construction Effectiveness in Liaoning Province During 2011–2015显示文摘At present, the large-scale construction of high-standard farmland in China has improved the quality of cropland and crop production and enhanced the eco-environmental security. To obtain a comprehensive understanding of high-standard farmland construction in Liaoning Province of China during the 12 th five-year period(2011–2015), through on-the-spot investigations and remote sensing monitoring, this study assessed the construction effectiveness of ten typical sampling projects in Liaoning Province and then presented practical suggestions. The main conclusions were as follows. 1) The ranges of increase in productivity of the ten sampling projects in Liaoning Province all surpassed the goal of 1500 kg/ha. 2) Among all sampling project areas, the levels of productivity stability of nine sampling projects were higher than that of the surrounding farmland in a severe drought year. However, the productivity stability of the high-standard farmland construction project in Faku County, Yiniupu Town, declined by 1.04% compared with the surrounding farmland. 3) Except for the high-standard farmland construction project in Dengta City, Dengta Irrigation Region, the productivity uniformity of the other nine sampling projects increased by 3.30%–88.10%. 4) Eight of the ten sampling projects belonged to Class 1, and two projects belonged to Class 2, showing that the effectiveness of high-standard farmland construction in Liaoning Province was quite good.There were some suggestions for high-standard farmland construction in the future. All departments should strengthen cooperation and formulate corresponding protection and development strategies suitable for local conditions. Additionally, lasting management mechanisms should also be established. Using remote sensing monitoring to assess the high-standard farmland construction effectiveness during the 12 th five-year period could provide experience and decision-making support for high-standard farmland construction in the future. | PU Luoman ZHANG Shuwen YANG Jiuchun YAN Fengqin CHANG Liping | 2019 | Chinese Geographical Science2019，29，4： | 4 |
| 14 | MULTIPLICITY OF POSITIVE SOLUTIONS TO MULTIPOINT BOUNDARY VALUE PROBLEM WITH ONE-DIMENSIONAL p-LAPLACIAN显示文摘In this paper, we consider a multipoint boundary value problem for one-dimensional p-Laplacian. Using a fixed point theorem due to Bai and Ge, we study the existence of at least three positive solutions to the boundary value problem. In this problem, the nonlinear term explicitly involves a first-order derivative, which is different from some previous ones. | Zhiyu Zhang (Dept. of Math., Taiyuan Institute of Technology, Taiyuan 030008) Youfeng Zhang (Yuncheng Middle School, Yuncheng 044000, Shanxi) Fengqin Zhang (Dept. of Math., Yuncheng University, Yuncheng 044000, Shanxi) | 2010 | Annals of Differential Equations2010，26，4： | 4 |
| 15 | China's Wetland Databases Based on Remote Sensing Technology显示文摘Wetland databases can provide the basic data that necessary for the protection and management of wetlands. A large number of wetland databases have been established in the world as well as in China. In this paper, we review China's wetland databases based on remote sensing(RS) technology after introducing the background theory to the application of RS technology in wetland surveys. A key conclusion is that China's wetland databases are far from sufficient in fulfilling protection and management needs. Our recommendations focus on the use of the hyper-spectral imagery, microwave data, multi-temporal images, and automatic classifications in order to improve the accuracy and efficiency of wetland inventory. Further, attention should also be paid to detect major biophysical features of wetlands and build wetland databases in years after the 1980 s in China. Considering that great gap exists between RS experts and wetland experts, further cooperation between wetland scientists and RS scientists are needed to promote the application of RS in the foundation of wetland databases. | YAN Fengqin LIU Xingtu CHEN Jing YU Lingxue YANG Chaobin CHANG Liping YANG Jiuchun ZHANG Shuwen | 2017 | Chinese Geographical Science2017，27，3： | 4 |
| 16 | Characteristics of soil seed banks at different geomorphic positions within the longitudinal sand dunes of the Gurbantunggut Desert, China显示文摘Understanding the characteristics of soil seed banks in sand dunes is crucial to stabilize the dune systems and maintain the plant populations in deserts. In this study, we conducted a survey investigation in the field and a seed germination experiment in the laboratory to explore the characteristics of soil seed banks at various geomorphic positions of longitudinal sand dunes in the Gurbantunggut Desert, China. Totally, 17 plant species belonging to 17 genera and 9 families were identified in soil seed banks, and 35 plant species belonging to 34 genera and 17 families were identified in aboveground vegetation. Plant species richness in soil seed banks decreased with increasing soil depth. The highest species richness was presented in the upper slope of the windward slope and the lowest species richness was presented in the base of the windward slope. There was no significant difference in seed density of soil seed banks among the examined seven geomorphic positions. The highest seed density occurred in the lower slope of the leeward slope while the lowest occurred in the crest. Moreover, seed density decreased with increasing soil depth, being the highest in the upper soil layer(0–2 cm). For both soil seed banks and aboveground vegetation, there was no significant difference in Simpson's diversity index among the seven geomorphic positions; however, Shannon-Wiener diversity index and Pielou's evenness index showed significant differences among the seven geomorphic positions. Those results showed that although there was no significant difference in seed density of soil seed banks among the seven geomorphic positions, the geomorphic positions significantly affected the species richness, diversity and distribution of soil seed banks. Therefore, understanding the characteristics of soil seed banks at different geomorphic positions of sand dunes is essential to vegetation restoration or reestablishment. Furthermore, the Jaccard's similarity coefficients of plant species between soil seed banks and aboveground vegetation at the seven geomorphic positions were low, suggesting that vegetation restoration or reestablishment processes should be promoted through adding seeds to surface layers. | JIA Fengqin Tashpolat TIYIP WU Nan TIAN Changyan ZHANG Yuanming | 2017 | Journal of Arid Land2017，9，3： | 3 |
| 17 | Co-fermented defatted rice bran alters gut microbiota and improves growth performance,antioxidant capacity,immune status and intestinal permeability of finishing pigs显示文摘Based on preparation of co-fermented defatted rice bran(DFRB)using Bacillus subtilis,Saccharomyces cerevisiae,Lactobacillus plantarum and phytase,the present study aimed to evaluate the effects of cofermented DFRB on growth performance,antioxidant capacity,immune status,gut microbiota and permeability in finishing pigs.Ninety finishing pigs(85.30±0.97 kg)were randomly assigned to 3treatments(3 replicates/treatment)with a basal diet(Ctrl),a basal diet supplemented with 10% unfermented DFRB(UFR),and a basal diet supplemented with 10% fermented DFRB(FR)for 30 d.Results revealed that the diet supplemented with FR notably(P<0.05)improved the average daily gain(ADG),gain to feed ratio(G:F)and the digestibility of crude protein,amino acids and dietary fiber of finishing pigs compared with UFR.Additionally,FR supplementation significantly(P<0.05)increased total antioxidant capacity,the activities of superoxide dismutase and catalase,and decreased the content of malonaldehyde in serum.Furthermore,FR remarkably(P<0.05)increased serum levels of Ig G,antiinflammatory cytokines(IL-22 and IL-23)and reduced pro-inflammatory cytokines(TNF-α,IL-1β and INF-γ).The decrease of serum diamine oxidase activity and serum D-lactate content in the FR group(P<0.05)suggested an improvement in intestinal permeability.Supplementation of FR also elevated the content of acetate and butyrate in feces(P<0.05).Moreover,FR enhanced gut microbial richness and the abundance of fiber-degrading bacteria such as Clostridium butyricum and Lactobacillus amylovorus.Correlation analyses indicated dietary fiber in FR was associated with improvements in immune status,intestinal permeability and the level of butyrate-producing microbe C.butyricum,which was also verified by the in vitro fermentation analysis.These findings provided an experimental and theoretical basis for the application of fermented DFRB in finishing pigs. | Weifa Su Zipeng Jiang Cheng Wang Yu Zhang Tao Gong Fengqin Wang Mingliang Jin Yizhen Wang Zeqing Lu | 2022 | Animal Nutrition2022，，4： | 3 |
| 18 | Global dynamics of a heroin epidemic model with age structure and nonlinear incidence显示文摘 | Junyuan Yang Xiaoxia Li Fengqin Zhang | 2016 | International Journal of Biomathematics2016，9，3： | 2 |
| 19 | The location of endogenous wild-type p53 protein in 293T and HEK293 cells expressing low-risk HPV-6E6 fusion protein with GFP显示文摘加重引起癌症的人的乳头状瘤病毒(HPV ) 的机制广泛地被学习了,并且高风险的 HPV 是 E6,这被结束指向并且降级的肿瘤 suppressor 蛋白质 p53,导致感染了房间恶意的转变。相反,低风险的 HPV 仅仅引起 proliferative 但是感染的 epithelia 的非侵略的损害。因此,我们假设了那低风险的 HPV 的 E6 可能在一个不同模式与 p53 交往。我们使用了一块哺乳动物的草地荧光灯表示 HPV-18E6 和 HPV-6E6 熔化蛋白质在的蛋白质(GFP ) 表示系统野类型(wt ) p53 房间线, 293T 和 HEK293 房间,调查 E6s 和 p53 的交通和地点。结果显示 GFP-18E6 主要在原子核被表示,而 GFP-6E6 专门在细胞质被表示。内长的 wt p53 被显示在有 GFP-18E6 的房间 transfected 的原子核局部性。第一次,有趣地,我们观察到 p53 在细胞质并且从未被套住 translocated 进有 GFP-6E6 的房间原子核 transfected。在结论, HPV-6E6 为 p53 的细胞质的本地化负责。因此,我们的实验提供新卓见进 HPV 的致病。 | Lina Sun Xinxin Shen Yan Liu Ge Zhang Jianchun Wei Huijuan Zhang Enming Zhang Fengqin Ma | 2010 | Acta Biochimica et Biophysica Sinica2010，42，3： | 2 |
| 20 | The C_(6)D_(6)detector system on the Back-n beam line of CSNS显示文摘Introduction The neutron capture cross sections are very important in the field of nuclear device design and basic physics research.Hydrogen-free liquid scintillator such as C_(6)D_(6)detectors are widely used in the neutron capture cross-sectional measurements for the low neutron sensitivity and fast time response.The Back-n white neutron source at China Spallation Neutron Source is the first spallation white neutron source in China,and it is suitable for neutron capture cross-sectional measurement.Materials and methods A C_(6)D_(6)detector system was built in the Back-n experimental station.The pulse height weighting technique was used to determine the system’s detection efficiency.The response to gamma rays of the C_(6)D_(6)detector was measured,and the energy resolution function was determined.Monte Carlo simulation with Geant4 code was carried out to get the weighting function of this C_(6)D_(6)detector system.Additionally,the systematic uncertainty of the weighting function was also determined.Conclusion According to the experimental and simulation results,this C_(6)D_(6)detector system can be used to measure neutron capture cross section. | Jie Ren Xichao Ruan Jie Bao Guangyuan Luan Wei Jiang Qi An Huaiyong Bai Ping Cao Qiping Chen Yonghao Chen Pinjing Cheng Zengqi Cui Ruirui Fan Changqing Feng Minhao Gu Fengqin Guo Changcai Han Zijie Han Guozhu He Yongcheng He Yuefeng He Hanxiong Huang Weiling Huang Xiru Huang Xiaolu Ji Xuyang Ji Haoyu Jiang Hantao Jing Ling Kang Mingtao Kang Bo Li Lun Li Qiang Li Xiao Li Yang Li Yang Li Rong Liu Shubin Liu Xingyan Liu Yinglin Ma Changjun Ning Binbin Qi Zhaohui Song Hong Sun Xiaoyang Sun Zhijia Sun Zhixin Tan Hongqing Tang Jingyu Tang Pengcheng Wang Qi Wang Taofeng Wang Yanfeng Wang Zhaohui Wang Zheng Wang Jie Wen Zhongwei Wen Qingbiao Wu Xiaoguang Wu Xuan Wu Likun Xie Yiwei Yang Han Yi Li Yu Tao Yu Yongji Yu Guohui Zhang Jing Zhang Linhao Zhang Liying Zhang Qingmin Zhang Qiwei Zhang Xianpeng Zhang Yuliang Zhang Zhiyong Zhang Yingtan Zhao Liang Zhou Zuying Zhou Danyang Zhu Kejun Zhu Peng Zhu | 2019 | Radiation Detection Technology and Methods2019，3，3： | 1 |
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