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| 1 | Mushroom Poisoning Outbreaks-China,2020显示文摘What is already known about this topic?Acute liver failure,rhabdomyolysis,acute renal failure,and hemolysis caused by poisonous mushrooms are the most important mushroom poisoning threats to the Chinese population.The most notorious lethal mushrooms are the species from genera Amanita,Lepiota,and Galerina that cause acute liver failure,and Russula subnigricans that leads to rhabdomyolysis.What is added by this report?In 2020,the total number of investigations reached 676,involving an estimated 102 species of poisonous mushrooms,24 of which were newly recorded in China.Gyromitra venenata was newly discovered in incidents in Yunnan and Guizhou provinces and were the first reported poisonings due to gyromitrins in China since 2000.The rare poisoning Shiitake mushroom dermatitis was recorded in China.Hemolysis poisoning caused by Paxillus involutus was recorded for the second time since the beginning of the new century,resulting in one death in Inner Mongolia Autonomous Region.What are the implications for public health practice?Promoting knowledge about safe consumption of mushrooms is essential to reduce mushroom poisonings.It is not wise to collect and eat wild mushrooms.For southwestern provinces such as Yunnan,especially,caution must be exercised with unfamiliar mushroom species. | Haijiao Li Hongshun Zhang Yizhe Zhang Jing Zhou Yu Yin Qian He Shaofeng Jiang Peibin Ma Yutao Zhang Ke Wen Yuan Yuan Nan Lang Bowen Cheng Junjia Lu Chengye Sun | 2021 | China CDC weekly2021，3，3： | 13 |
| 2 | Mushroom Poisoning Outbreaks--China,2019显示文摘What is already known about this topic?Mushroom poisoning is becoming one of the most serious food safety issues in China,which is responsible for nearly a half of all oral poisoning deaths.What is added by this report?In China,many mushrooms were previously“recorded”as poisonous.In this study,about 70 species obtained from mushroom poisoning incidents including several new records were confirmed accurately by morphological and molecular evidence in 2019,and spatial and temporal distribution characters of 13 lethal mushrooms were summarized systematically.What are the implications for public health practice?Precise and timely species identification is of pivotal importance in mushroom incidents.More efforts and cooperation are continued to be needed urgently for the governments,CDC staff,doctors and mycologists in future. | Haijiao Li Hongshun Zhang Yizhe Zhang Kaiping Zhang Jing Zhou Yu Yin Shaofeng Jiang Peibin Ma Qian He Yutao Zhang Ke Wen Yuan Yuan Nan Lang Junjia Lu Chengye Sun | 2020 | China CDC weekly2020，2，2： | 11 |
| 3 | Mushroom Poisoning Outbreaks — China, 2021显示文摘Summary What is already known about this topic?Mushroom poisoning is one of the most serious food safety issues in China.Most poisoning incidents resulted from eating mushrooms causing gastroenteritis and psycho-neurological disorder from which patients usually could fully recover.Most deaths resulted from species causing acute liver failure and rhabdomyolysis,and the remaining deaths were attributed to acute renal failure and hemolysis.What is added by this report?In 2021,the total number of investigations was 327 from 25 provincial-level administrative divisions,involving 923 patients and 20 deaths,and the overall mortality was 2.17%.Overall,74 poisonous mushrooms causing 6 different clinical syndromes were successfully identified,15 of which were newly recorded in China as poisonous mushrooms.What are the implications for public health practice?Considering the potential huge risks for collecting and eating wild mushrooms,we strongly advise not collecting and eating unfamiliar wild mushrooms.Promoting knowledge about poisonous mushrooms is essential and urgent to reduce mushroom poisonings.Precise species identification timely after mushroom poisoning is important for appropriate diagnosis and treatment.Many deaths were ascribed to delayed hospitalization. | Haijiao Li Hongshun Zhang Yizhe Zhang Jing Zhou Yu Yin Qian He Shaofeng Jiang Peibin Ma Yutao Zhang Yuan Yuan Nan Lang Bowen Cheng Mei Wang Chengye Sun | 2022 | China CDC weekly2022，4，3： | 7 |
| 4 | Mushroom Poisoning Outbreaks -China, 2022显示文摘Mushroom poisoning has become a serious food safety issue in China.With the support of the government,over the past decade,China has gradually established a mushroom poisoning prevention and treatment system involving experts in disease prevention and control,clinical diagnosis and treatment,fungal classification,and basic medicine(1–3). | Haijiao Li Yizhe Zhang Hongshun Zhang Jing Zhou Jiaqi Liang Yu Yin Qian He Shaofeng Jiang Yutao Zhang Yuan Yuan Nan Lang Bowen Cheng Mei Wang Chengye Sun | 2023 | China CDC weekly2023，5，3： | 4 |
| 5 | Poisonings Caused by Wild Mushroom Containing Amanitin Toxins—Shaoxing City,Zhejiang Province,China,2019显示文摘What is already known about this topic?Among all food poisoning,poisonings caused by wild mushrooms containing amanitin toxins have the highest case fatality rate.Amanitin toxins can cause acute liver function damage,and symptoms of the poisoning can include vomiting and diarrhea in early stages and progressive liver damage 2–3 days later.What is added by this report?Before 2019,there were about 1–2 cases of wild mushroom containing amanitin toxins poisoning each year in Zhejiang Province.In 2019,10 cases were identified through disease investigation and toxin detection and biological identification in Shaoxing City,Zhejiang Province.All patients had a history of wild mushroom consumption.What are the implications for public health practice?In the summer,some people collect the wild mushrooms for consumption.In China,about 20 species of mushrooms can cause death,and most people lack the ability to identify which mushrooms are edible.To combat this,effective science popularization and prevention and control work will be able to reduce the occurrence of related poisoning events. | Xiaomin Xu Liang Sun Yizhe Zhang Jiayang Song Chao Xing Hongshun Zhang | 2020 | China CDC weekly2020，2，29： | 2 |
| 6 | Multi-variable Dependent Forecast Algorithm for Predicting Secondary Arc显示文摘Hybrid reactive power compensation(HRPC)combines step-controlled shunt reactors and series compensation,and will be employed in ultra-high-voltage(UHV)power systems.The single-phase auto-reclosure characteristics of secondary arcs in systems with HRPC require further investigation.In this paper,both the arc-recalling voltage and subsidiary variations in arc current are investigated with and without HRPC.The frequency components of the secondary arc current and variations in arcing time are analyzed for various influential factors,such as the neutral reactor,arc resistance,fault location,degrees of compensation of HRPC,and the length of the transmission line.The non-dominated sorting genetic algorithm II(NSGA-II)and support vector machine regression are combined to create a multi-variable dependent forecasting algorithm to predict the characteristics of the secondary arc in UHV systems with HRPC.This paper provides a theoretical reference for optimizing the parameters of HRPC,and for developing adaptive auto-reclosure schemes and protection equipment. | Hongshun Liu Jian Guo Dongxin He Mingming Han Ying Sun Jingjing Yang Qingquan Li | 2020 | CSEE Journal of Power and Energy Systems2020，6，2： | 1 |
| 7 | Changes in firmness, pectin content and nanostructure of two crisp peach cultivars after storage显示文摘 | Lifen Zhang Fusheng Chen Hongshun Yang Xiaoyang Sun Hui Liu Xiangzhe Gong Chongbin Jiang Changhe Ding | 2009 | LWT - Food Science and Technology2009，，1： | 1 |
| 8 | Inhibition of beta-site amyloid precursor protein-cleaving enzyme and beta-amyloid precursor protein genes in SK-N-SH cells显示文摘BACKGROUND:Previous studies have demonstrated that Piper futokadsura stem selectively inhibits expression of amyloid precursor protein(APP) at the mRNA level.In addition,the piperlonguminine(A) and dihydropiperlonguminine(B) components(1:0.8),which can be separated from Futokadsura stem,selectively inhibit expression of the APP at mRNA and protein levels. OBJECTIVE:Based on previous findings,the present study investigated the effects ofβ-site amyloid precursor protein cleaving enzyme(BACE1) and APP genes on the production ofβ-amyloid peptide 42(Aβ42) in human neuroblastoma cells(SK-N-SH cells) using small interfering RNAs (siRNAs) and A/B components separated from Futokadsura stem,respectively. DESIGN,TIME AND SETTING:A gene interference-based randomized,controlled,in vitro experiment was performed at the Key Laboratory of Cardiovascular Remodeling and Function Research,Ministries of Education and Public Health,and Institute of Pharmacologic Research, School of Pharmaceutical Science & Department of Biochemistry,School of Medicine,Shandong University between July 2006 and December 2007. MATERIALS:SK-N-SH cells were provided by Shanghai Institutes of Biological Sciences,Chinese Academy of Sciences,Shanghai,China;mouse anti-human BACE1 monoclonal antibody was purchased from R&D Systems,USA;mouse anti-human APP monoclonal antibody was purchased from Cell Signaling Technology,USA;and horseradish peroxidase(HRP)-conjugated goat anti-mouse IgG was provided by Sigma,USA. METHODS:The human BACE1 cDNA sequence was obtained from NCBI website (www.ncbi.nlm.nih.gov/sites/entrez).Three pairs of siRNAs,specific to human BACE1 gene,were synthesized through the use of Silencer^(?) pre-designed siRNA specification,and were transfected into SK-N-SH cells with siPORT NeoFX transfection agent to compare the effects of different concentrations of siRNAs(10-50 nmol/L) on SK-N-SH cells.Futokadsura stem was separated and purified with chemical methods,and the crystal was composed of A/B components,with an A to B ratio of 1:0.8.The A/B(1:0.8) components were added to the SK-N-SH cells at different concentrations(13.13,6.56,and 3.28 mg/mL). MAIN OUTCOME MEASURES:Using RT-PCR and Western blot methods,BACE1 and APP expression at mRNA and protein levels was detected in SK-N-SH cells following treatment with different siRNAs and concentrations of Futokadsura stem-separated A/B components,respectively. Altered Aβ42 secretion by SK-N-SH cells was determined by ELISA. RESULTS:BACE1 mRNA and protein levels were significantly suppressed by 40 and 50 nmol/L siRNAs at 48 hours post-transfection.A/B components(1:0.8),which were separated from Futokadsura stem,selectively inhibited mRNA and protein expression of APP in SK-N-SH cells. Aβ42 secretion by SK-N-SH cells was significantly decreased following treatment with siRNAs or A/B components. CONCLUSION:Inhibition of BACE1 and APP genes by various materials and methods efficiently decreased production of Aβ42. | Suqin Gao Lin Sun Enji Han Hongshun Qi Jinbo Feng Shunliang Xu Wen Xia | 2009 | Neural Regeneration Research2009，4，6： | 0 |
| 9 | Contamination degree prediction of insulator surface based on exploratory factor analysis-least square support vector machine combined model显示文摘This study presents a combined model based on the exploratory factor analysis(EFA)and the least square support vector machine(LSSVM)to predict the contamination degree of insulator surface.Firstly,EFA method is utilised to reduce numerous influence factor variables of the insulator contamination into a few factor variables,which could decrease the complexity of the model.Then,regarding the above factor variables as new input variables,LSSVM model is established to predict the insulator contamination de-gree.In order to obtain the optimal predictive value,the non-dominated sorting genetic algorithm II is applied on the optimization of LSSVM model parameters.The proposed EFA-LSSVM combined model is compared with the models of LSSVM,back propa-gation neural network,and multiple linear regression on the model performance.Results indicate that the EFA-LSSVM combined model in this study effectively overcomes the shortcomings of the other three models mentioned above in computational time,pre-diction accuracy and generalization ability.Finally,the feasibility of the proposed model in predicting contamination degree of insulator surface is verified by adopting the radar map of the evaluation indexes of model performance. | Jiaxiang Sun Hongru Zhang Qingquan Li Hongshun Liu Xinbo Lu Kaining Hou | 2021 | High Voltage2021，6，2： | 0 |
| 10 | Mushroom Poisoning Outbreaks—China,2023显示文摘Summary What is already known about this topic?Mushroom poisoning poses a significant food safety concern in China,with a total of 196 species identified in poisoning incidents by the end of 2022.What is added by this report?In 2023,the China CDC conducted an investigation into 505 cases of mushroom poisoning spanning 24 provincial-level administrative divisions.This investigation resulted in 1,303 patients and 16 deaths,yielding a case fatality rate of 1.23%.A total of 97 mushrooms were identified as the cause of 6 distinct clinical disease types,with 12 species newly documented as poisonous mushrooms in China.What are the implications for public health practice?Close collaboration among CDC staff,physicians,and mycologists remains crucial for the control and prevention of mushroom poisoning in the future. | Haijiao Li Yizhe Zhang Hongshun Zhang Jing Zhou Zuohong Chen Jiaqi Liang Yu Yin Qian He Shaofeng Jiang Yutao Zhang Yuan Yuan Nan Lang Bowen Cheng Jiaju Zhong Zhongfeng Li Chengye Sun | 2024 | China CDC weekly2024，6，4： | 0 |
| 11 | Reflection-type surface lattice resonances in all-metal metasurfaces for refractive index sensing显示文摘Surface lattice resonance(SLR)is a pretty effective mechanism to realize ultranarrow linewidths in the spectrum.Herein,we propose and demonstrate reflection-type SLRs in all-metal metasurfaces experimentally,compared with the traditional transmission-type SLR,which can avoid the refractive index(RI)mismatch problem and are more suitable for high-efficiency RI sensing due to direct contact and strong light–matter interaction.The measured SLR linewidth is 13.5 nm influenced by the meta-atom size,which needs a compromise design to keep a balance between the narrow linewidth and noise immunity.Notably,the SLR sensitivity is determined by the lattice period along the polarization direction with regularity,which establishes an intuitive link between structures and optical responses and provides a theoretical guide for metasurface designs.Additionally,incident angle multiplexing will make the resonance wavelength red shift or blue shift in the case of orthogonal polarization.The rectangular array metasurface can realize dual SLRs with different sensing performances.Flexibly,the SLR can also be formed by the different meta-atoms and arrays.This research supports SLR multifarious applications involving not only RI sensing but also nonlinear optics,nano-lasers,etc. | LIYE LI YIFAN OUYANG LIJUN MA HONGSHUN SUN YUSA CHEN MEIZHANG WU ZHIMEI QI WENGANG WU | 2023 | Photonics Research2023，11，12： | 0 |
| 12 | Improved information entropy weighted vague support vector machine method for transformer fault diagnosis显示文摘A combined model based on improved information entropy and vague support vector machine(IVSVM)is introduced into transformer fault diagnosis using dissolved gas analysis in oil(DGA).The improved information entropy method is used to obtain the weights of each gas and to weight the raw data,and the processed training data and the corresponding fault types are inputted into the vague support vector machine(VSVM)model to obtain classifiers.Firstly,the training data are weighted by the improved information entropy method to discretise the original data from the mixed state for subsequent classifier training.Then,the vague set divides the events into true,false and unknown factors,which can optimise the sub-interface of SVM and improve the accuracy of the boundary point clas-sification.Finally,fault data from the literature and actual collections are selected for training and testing.By comparing with the widely used ratio method and artificial intelligence method,it can be concluded that the method described herein can effectively improve the accuracy of fault diagnosis.The result shows that this method has better applicability when facing actual fault type classification with higher data similarity. | Hongru Zhang Jiaxiang Sun Kaining Hou Qingquan Li Hongshun Liu | 2022 | High Voltage2022，7，3： | 0 |
| 13 | A Poisoning Outbreak Caused by Anisodus tanguticus — Maqin County, Qinghai Province, China, July 2021显示文摘Summary What is already known about this topic?Anisodus tanguticus belongs to the Solanaceae family.The plant is toxic due to the tropane alkaloids it contains and can cause poisoning when it is ingested or used inappropriately.What is added by this report?A poisoning outbreak involved 10 patients,and one death was caused by Anisodus tanguticus.The etiological association of plant exposure and poisoning was confirmed with evidence from an epidemiological investigation,clinical manifestations,plant identification and a toxin analysis. | Xuebin Guo Qian He Bangguo Qi Chenye Sun DongJin Lyu Hongshun Zhang | 2022 | China CDC weekly2022，4，41： | 0 |
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