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| 1 | Progress in wearable electronics/photonics—Moving toward the era of artificial intelligence and internet of things显示文摘The past few years have witnessed the significant impacts of wearable electronics/photonics on various aspects of our daily life,for example,healthcare monitoring and treatment,ambient monitoring,soft robotics,prosthetics,flexible display,communication,human-machine interactions,and so on.According to the development in recent years,the next-generation wearable electronics and photonics are advancing rapidly toward the era of artificial intelligence(AI)and internet of things(IoT),to achieve a higher level of comfort,convenience,connection,and intelligence.Herein,this review provides an opportune overview of the recent progress in wearable electronics,photonics,and systems,in terms of emerging materials,transducing mechanisms,structural configurations,applications,and their further integration with other technologies.First,development of general wearable electronics and photonics is summarized for the applications of physical sensing,chemical sensing,humanmachine interaction,display,communication,and so on.Then self-sustainable wearable electronics/photonics and systems are discussed based on system integration with energy harvesting and storage technologies.Next,technology fusion of wearable systems and AI is reviewed,showing the emergence and rapid development of intelligent/smart systems.In the last section of this review,perspectives about the future development trends of the next-generation wearable electronics/photonics are provided,that is,toward multifunctional,self-sustainable,and intelligent wearable systems in the AI/IoT era. | Qiongfeng Shi Bowei Dong Tianyiyi He Zhongda Sun Jianxiong Zhu Zixuan Zhang Chengkuo Lee | 2020 | InfoMat2020，2，6： | 17 |
| 2 | Constructing a high-density linkage map for Gossypium hirsutum × Gossypium barbadense and identifying QTLs for lint percentage显示文摘To introgress the good fiber quality and yield from Gossypium barbadense into a commercial Upland cotton variety, a high-density simple sequence repeat(SSR) genetic linkage map was developed from a BC1F1 population of Gossypium hirsutum×Gossypium barbadense. The map comprised 2,292 loci and covered 5115.16 centi Morgan(c M) of the cotton AD genome, with an average marker interval of 2.23 c M. Of the marker order for 1,577 common loci on this new map, 90.36% agrees well with the marker order on the D genome sequence genetic map. Compared with five published high-density SSR genetic maps, 53.14% of marker loci were newly discovered in this map. Twenty-six quantitative trait loci(QTLs) for lint percentage(LP) were identified on nine chromosomes. Nine stable or common QTLs could be used for marker-assisted selection. Fifty percent of the QTLs were from G. barbadense and increased LP by 1.07%–2.41%. These results indicated that the map could be used for screening chromosome substitution segments from G. barbadense in the Upland cotton background, identifying QTLs or genes from G. barbadense, and further developing the gene pyramiding effect for improving fiber yield and quality. | Yuzhen Shi Wentan Li Aiguo Li Ruihua Ge Baocai Zhang Junzhi Li Guangping Liu Junwen Li Aiying Liu Haihong Shang Juwu Gong Wankui Gong Zemao Yang Feiyü Tang Zhi Liu Weiping Zhu Jianxiong Jiang Xiaonan Yu Tao Wang Wei Wang Tingting Chen Kunbo Wang Zhengsheng Zhang Youlu Yuan | 2015 | Journal of Integrative Plant Biology2015，57，5： | 7 |
| 3 | MATRIEX imaging:multiarea two-photon real-time in vivo explorer显示文摘Two-photon laser scanning microscopy has been extensively applied to study in vivo neuronal activity at cellular and subcellular resolutions in mammalian brains.However,the extent of such studies is typically confined to a single functional region of the brain.Here,we demonstrate a novel technique,termed the multiarea two-photon real-time in vivo explorer(MATRIEX),that allows the user to target multiple functional brain regions distributed within a zone of up to 12mm in diameter,each with a field of view(FOV)of ~200μm in diameter,thus performing two-photon Ca2+imaging with single-cell resolution in all of the regions simultaneously.For example,we demonstrate real-time functional imaging of single-neuron activities in the primary visual cortex,primary motor cortex and hippocampal CA1 region of mice in both anesthetized and awake states.A unique advantage of the MATRIEX technique is the configuration of multiple microscopic FOVs that are distributed in three-dimensional space over macroscopic distances(>1 mm)both laterally and axially but that are imaged by a single conventional laser scanning device.In particular,the MATRIEX technique can be effectively implemented as an add-on optical module for an existing conventional single-beam-scanning two-photon microscope without requiring any modification to the microscope itself.Thus,the MATRIEX technique can be readily applied to substantially facilitate the exploration of multiarea neuronal activity in vivo for studies of brain-wide neural circuit function with single-cell resolution. | Mengke Yang Zhenqiao Zhou Jianxiong Zhang Shanshan Jia Tong Li Jiangheng Guan Xiang Liao Bing Leng Jing Lyu Kuan Zhang Min Li Yan Gong Zhiming Zhu Junan Yan Yi Zhou Jian K Liu Zsuzsanna Varga Arthur Konnerth Yuguo Tang Jinsong Gao Xiaowei Chen Hongbo Jia | 2019 | Light(Science & Applications)2019，8，1： | 4 |
| 4 | Deep learning-enabled triboelectric smart socks for IoT-based gait analysis and VR applications显示文摘The era of artificial intelligence and internet of things is rapidly developed by recent advances in wearable electronics.Gait reveals sensory information in daily life containing personal information,regarding identification and healthcare.Current wearable electronics of gait analysis are mainly limited by high fabrication cost,operation energy consumption,or inferior analysis methods,which barely involve machine learning or implement nonoptimal models that require massive datasets for training.Herein,we developed low-cost triboelectric intelligent socks for harvesting waste energy from low-frequency body motions to transmit wireless sensory data.The sock equipped with self-powered functionality also can be used as wearable sensors to deliver information,regarding the identity,health status,and activity of the users.To further address the issue of ineffective analysis methods,an optimized deep learning model with an end-to-end structure on the socks signals for the gait analysis is proposed,which produces a 93.54%identification accuracy of 13 participants and detects five different human activities with 96.67%accuracy.Toward practical application,we map the physical signals collected through the socks in the virtual space to establish a digital human system for sports monitoring,healthcare,identification,and future smart home applications. | Zixuan Zhang Tianyiyi He Minglu Zhu Zhongda Sun Qiongfeng Shi Jianxiong Zhu Bowei Dong Mehmet Rasit Yuce Chengkuo Lee | 2020 | npj Flexible Electronics2020，4，1： | 4 |
| 5 | Generation and characterization of stable pig pregastrulation epiblast stem cell lines显示文摘Pig epiblast-derived pluripotent stem cells are considered to have great potential and broad prospects for human therapeutic model developme nt and livestock breeding.Despite on going attempts since the 1990s,no stably defined pig epiblast-derived stem cell line has bee n established.Here,guided by in sights from a large-scale sin gle-cell tran scriptome an alysis of pig embryos from embryonic day(E)0 to E14,specifically,the tracing of pluripotency changes during epiblast development,we developed an in vitro culture medium for establishing and maintaining stable pluripotent stem cell lines from pig E10 pregastrulation epiblasts(pgEpiSCs).Enabled by chemical inhibition of WNT-related signaling in combination with growth factors in the FGF/ERK,JAK/STAT3,and Activin/Nodal pathways,pgEpiSCs maintain their pluripotency transcriptome features,similar to those of E10 epiblast cells,and normal karyotypes after more than 240 passages and have the potential to differentiate into three germ layers.Strikingly,ultradeep in situ Hi-C analysis revealed functional impacts of chromatin 3D-spatial associations on the transcriptional regulation of pluripote ncy marker genes in pgEpiSCs.I n practice,we con firmed that pgEpiSCs readily tolerate at least three rounds of successive gene editi ng and gene rated cloned gen e-edited live piglets.Our findings deliver on the long-a nticipated promise of pig pluripote nt stem cells and open new avenues for biological research,animal husbandry,and regenerative biomedicine. | Minglei Zhi Jinying Zhang Qianzi Tang Dawei Yu Shuai Gao Dengfeng Gao Pengliang Liu Jianxiong Guo Tang Hai Jie Gao Suying Cao Zimo Zhao Chongyang Li Xiaogang Weng Mengnan He Tianzhi Chen Yingjie Wang Keren Long Deling Jiao Guanglei Li Jiaman Zhang Yan Liu Yu Lin Daxin Pang Qianqian Zhu Naixin Chen Jingjing Huang Xinze Chen Yixuan Yao Jingcang Yang Zicong Xie Xianya Huang Mengxin Liu Ran Zhang Qiuyan Li Yiliang Miao Jianhui Tian Xingxu Huang Hongsheng Ouyang Bofeng Liu Wei Xie Qi Zhou Zhonghua Liu Caihong Zheng Mingzhou Li Jianyong Han | 2022 | Cell Research2022，32，4： | 3 |
| 6 | Numerical Investigation of Centerline Curvature Effects on a Compact S-shaped Intake显示文摘Taking into account stealth, structure and maintenance, ultra-compact S-shaped intake has been widely used in modern vehicles. In this paper a series of steady numerical simulation were carried out to investigate the complex flow mechanism in s-shaped intake, particular attention was given to examining the effect of centerline curvature on the performance and flowfield of an ultra-compact S-shaped intake. In order to validate the multi-block model, the computational results for Royal Aircraft Establishment intake 2129-M2129 which had modest centerline curvature distribution were corrected with available experimental test data. The numerical simulation results agreed fairly well with the experimental data, and the computational method was then used to investigate the effects of different centerline curvature distributions on performance and flow field in compact S-shaped intake. Detailed analyses of the flow visualization had exposed the different flow topologies between the cases with different centerline curvature. It was found that different centerline curvature distributions changed the initial location and the size of separation bubble, as well as the strength of two counter-rotating vortices at the entrance of engine. | Enliang Huang Shengfeng Zhao Zhijun Lei Jianxiong Kang Xingen Lu Junqiang Zhu | 2012 | Journal of Thermal Science2012，21，5： | 1 |
| 7 | Pre-protective effect of lipoic acid on injury induced by H 2 O 2 in IPEC-J2 cells显示文摘 | Xuan Cai Xiaolian Chen Xiaochun Wang Congcong Xu Qi Guo Lihui Zhu Shuwen Zhu Jianxiong Xu | 2013 | Molecular and Cellular Biochemistry2013，，1： | 1 |
| 8 | Correlative investigation of copper/low-density polyethylene nanocomposite on the endometrial angiogenesis in rats显示文摘The purpose of this study was to investigate the effects of copper/low-density polyethylene nanocomposite(nano-Cu/LDPE)on the endometrial angiogenesis in rats,and 100 sexual mature female SD rats were randomly divided into five groups:sham-operation groups(SO group,n=20),bulk copper groups(Cu group,n=20),LDPE groups(n=20),nano-Cu/LDPE groups I(n=20)and II(n=20).The levels of angiopoietin-2(Ang-2),its receptor(Tie-2)and CD34 of the rats’endometria in each group were examined by using the S-P method of the immunohistochemistry 30 and 180 days after insertion,respectively.Compared with those in the SO group,the expression of Ang-2 and Tie-2 in all the experimental groups was obviously increased 30 days after insertion,and these parameters in nano-Cu/LDPE groups,except for Ang-2 level in nano-Cu/LDPE group II,were significantly lower in comparison with those in Cu group(P<0.05).On the 180th day after insertion,Ang-2 and Tie-2 levels were still higher in Cu group and LDPE group,but there was no difference of Ang-2 and Tie-2 levels between nano-Cu/LDPE groups and the SO group(P>0.05).Com-pared with those in the SO group,the significant increases in microvessel density(MVD)were observed on the 30th and the 180th day after the insertion of the bulk copper(P<0.05).There was no significant difference in MVD counts before and after the insertion of nano-Cu/LDPE(P>0.05).The results show that Nano-Cu/LDPE have slighter influence on the endometrial angiogenesis than bulk copper. | LI Jianxiong LIU Zilong LI Shuang XIE Changsheng DUAN Yonggang YU Jing ZHU Changhong | 2007 | Frontiers of Medicine2007，1，4： | 1 |
| 9 | Deep learning enhanced lithium-ion battery nonlinear fading prognosis显示文摘With the assistance of artificial intelligence,advanced health prognosis technique plays a critical role in the lithium-ion(Li-ion) batteries management system.However,conventional data-driven early aging prediction exhibited dramatic drawbacks,i.e.,volatile capacity nonlinear fading trajectories create obstacles to the accurate multistep ahead prediction due to the complex working conditions of batteries.Herein,a novel deep learning model is proposed to achieve a universal and accurate Li-ion battery aging prognosis.Two battery datasets with various electrode types and cycling conditions are developed to validate the proposed approaches.Knee-point probability(KPP),extracted from the capacity loss curve,is first proposed to detect knee points and improve state-of-health(SOH) predictive accuracy,especially during periods of rapid capacity decline.Using one-cycle data of partial raw voltage as the model input,the SOH and KPP can be simultaneously predicted at multistep ahead,whereas the conventional method showed worse accuracy.Furthermore,to explore the underlying characteristics among various degradation tendencies,an online model update strategy is developed by leveraging the adversarial adaptationinduced transfer learning technique.This work gains new sights into the comprehensive Li-ion battery management and prognosis framework through decomposing capacity degradation trajectories and adversarial learning on the unlabeled samples. | Shanling Ji Jianxiong Zhu Zhiyang Lyu Heze You Yifan Zhou Liudong Gu Jinqing Qu Zhijie Xia Zhisheng Zhang Haifeng Dai | 2023 | Journal of Energy Chemistry2023，，3： | 0 |
| 10 | When and How to Adjust Non-Pharmacological Interventions Concurrent with Booster Vaccinations Against COVID-19—Guangdong,China,2022显示文摘Introduction:With the large-scale roll-out of the coronavirus disease 2019(COVID-19)booster vaccination effort(a vaccine dose given 6 months after completing primary vaccination)in China,we explore when and how China could lift non-pharmacological interventions(NPIs)against COVID-19 in 2022.Methods:Using a modified susceptible-infectiousrecovered(SIR)mathematical model,we projected the COVID-19 epidemic situation and required medical resources in Guangdong Province,China.Results:If the number of people entering from overseas recovers to 20%of the number in 2019,the epidemic in 2022 could be controlled at a low level by a containment(215 local cases)or suppression strategy(1,397 local cases).A mitigation strategy would lead to 21,722 local cases.A coexistence strategy would lead to a large epidemic with 6,850,083 local cases that would overwhelm Guangdong’s medical system.With 50%or 100%recovery of the 2019 level of travelers from overseas,the epidemic could also be controlled with containment or suppression,but enormous resources,including more hotel rooms for border quarantine,will be required.However,coexistence would lead to an uncontrollable epidemic with 12,922,032 local cases.Discussion:With booster vaccinations,the number of travelers from overseas could increase slightly in 2022,but a suppression strategy would need to be maintained to ensure a controllable epidemic. | Guanhao He Fangfang Zeng Jianpeng Xiao Jianguo Zhao Tao Liu Jianxiong Hu Sicong Zhang Ziqiang Lin Huaiping Zhu Dan Liu Min Kang Haojie Zhong Yan Li Limei Sun Yuwei Yang Zhixing Li Zuhua Rong Weilin Zeng Xing Li Zhihua Zhu Xiaofeng Liang Wenjun Ma | 2022 | China CDC weekly2022，4，10： | 0 |
| 11 | Comparison of Different-sized Chromite Mineralizations in the Yarlung-Zangbo Ophiolite Belt, Southern Tibet显示文摘Podiform chromitites are characteristically occurred in ophiolites(e.g.,Thayer,1964;Dickey,1975).However,the metallogenic processes for podiform chromitites are still unclear.Early models involved fractional crystallization and crystal settling from picritic or basaltic melts in magma chambers(Dickey,1975;Boudier and Coleman,1981),but it was also proposed that podiform chromitites formed from partial melting and melt extraction in host mantle peridotites(Dick,1977;Dick and Bullen,1984).Recent studies by the majority of authors have suggested that melt-rock interaction at the Moho transition zone may have played a key role in the formation of podiform chromitites(Zhou and Robinson,1994;Zhou et al.,1996,2005,2014;Robinson,2008;Page and Barnes,2009;Uysal et al.,2009,2012;González-Jiménez et al.,2011,2015).Based on the occurrence of some ultrahigh pressure minerals(e.g.diamond and coesite)in chromitites,it has been proposed recently that the formation of podiform chromitite is likely related to multiple processes inclusing mantle recycling(Yang et al.,2007;Yamamoto et al.,2013).Although geat progresses have been made towards understanding the genesis of podiform chromitites,some fundamental issues in remain unanswered.For examples,what are the major controls on the size of chromitites?And why some ophiolites contain large podiform chromitite bodies,whereas most ophiolitic massifs are essentially chromitite-barren? The Yarlung-Zangbo Ophiolite belt is one of the most famous ophiolite zone in the world.It contains fresh peridotites as well as different-sided podiform chromitites.The Luobusha ophiolite in the eastern segment of the belt hosts the largest chromite deposit in China.In the central and western segments of belt the Dazhuqu and Dongbo ophiolitic massifs contain some small-scale chromitite bodies.Such characteristics make the Yarlung-Zangbo Ophiolites an ideal subject to investigate the major controls on the metallogenesis of podiform chromitites. The Luobusha chromitites are large lens and enclosed in dunite.In contrast,the Dazhuqu and Dongbo chromitites display generally as narrow dykes or irregular seams with dunite envelopes.The closely spatial association of the chromitites and dunite envelopes,together with their textural features,support a petrogenetic model that the chromitites from the Luobusha,Dazhuqu and Dongbo massifs form from reaction of melt with host peridotite.In terms of chemical composition of chromite,there are distinctive differences between those from the Luobusha and the Dazhuqu or the Dongbo.Chromite from the Luobusha chromitites has high Cr#(71-82),whereas Chromite in the Dazhuqu chromitites show relatively low Cr#(16-63),and chromite in the Dongbo chromitites includes low Cr#(11-47)and high Cr#(70-81)types.For the Dongbo and Dazhuqu massifs,linear trends of Cr#with Mg O,Fe Ot,Ni,Ga,V and Sc in chromite from the chromitites and dunites of are similar to those of the host peridotites,suggesting that the melt-rock reaction may provide major budget of Cr for the chromitites.The similar compositions at a given Cr#in chromite from these rocks also demonstrate that the chromitites may have been formed by in-situ crystallization of chromite under low melt/rock ratio.In contrast,the Luobusha chromitites have different trends of compositions in chromite from that of the host peridotites,implying that the formation of the chromitite bodies requires a continual replenishment of Cr-rich melts from deeper mantle.Fractionation and accumulation of chromite from a large volume of Cr-rich melt may play an important role on the formation of the Luobusha chromitites.MORB-normalized trace element patterns of chromite from the Luobusha chromitites suggest that it has been formed from Cr-rich boninitic melt at surpra-subduction zone(SSZ)setting.However,the Dongbo and Dazhuqu chromitites have formed originally from a MORB-affinity melt at a mid-ocean ridge(MOR)environment. In summary,the Luobusha chromitites crystallized from a Cr-rich melt in a dynamic conduit,where fractional crystallization and crystal settling play a key role in formation of the large chromitites.In contrast,the small-scale mineralizations of the Dongbo and Dazhuqu chromitite pods are formed from in situ produced melts.Podiform chromitites can be formed in MOR environment,whereas the higher Cr content in boninitic melt and assimilation of subducted slab materials at SSZ setting may benefit the formation of large chromite deposit. | ZHU Xiangkun SHE Yuwei HE Yuan MA Jianxiong SUN Jian | 2017 | Acta Geologica Sinica(English Edition)2017，91，S1： | 0 |
| 12 | Titanium Isotope Analysis of Igneous Reference Materials using a Double-spike MC-ICP-MS Method显示文摘Ti separation was achieved by ion-exchange chromatography using Bio-Rad AG 1-X8 anion-exchange and DGA resins.For high-Fe/Ti and high-Mg/Ti igneous samples,a three-column procedure was required,whereas a two-column procedure was used for low-Fe/Ti and low-Mg/Ti igneous samples.The Ti isotopes were analysed by MC-ICP-MS,and instrumental mass bias was corrected using a ^(47)Ti-^(49)Ti double-spike technique.The ^(47)Ti-^(49)Ti double-spike and SRM 3162a were calibrated using SRM 979-Cr,certificated value ^(53)Cr/^(52)Crt rue=0.11339.Isobaric interference was evaluated by analysing Alfa-Ti doped with Na,Mg,Ca,and Mo,and results indicate that high concentrations of Na and Mg have no significant effect on Ti isotope analyses;however,Ca and Mo interferences lead to erroneousδ^(49/47)Ti values when Ca/Ti and Mo/Ti ratios exceed 0.01 and 0.1,respectively.Titanium isotopic compositions were determined for 12 igneous reference materials,BCR-2,BHVO-2,GBW07105,AGV-1,AGV-2,W-2,GBW07123,GBW07126,GBW07127,GBW07101,JP-1,and DTS-2b.Samples yieldδ^(49/47)Ti(‰)of−0.035±0.022,−0.038±0.031,0.031±0.022,0.059±0.038,0.044±0.037,0.000±0.015,0.154±0.044,−0.044±0.018,0.010±0.022,0.064±0.043,0.169±0.034,and−0.047±0.025(relative to OL-Ti,±2SD),respectively;of which isotopic compositions of DTS-2b,JP-1,GBW07101,GBW07105,GBW07123,GBW07126,and GBW07127 are reported for the first time.Standard Alfa-Ti was analysed repeatedly over a ten-month period,indicating a reproducibility of±0.047(2SD)forδ^(49/47)Ti,similar to the precisions obtained for geochemical reference materials. | LI Jin TANG Suohan ZHU Xiangkun MA Jianxiong ZHAO Xinmiao | 2022 | Acta Geologica Sinica(English Edition)2022，96，2： | 0 |
| 13 | Pt nanodendrites with (111) crystalline facet as an efficient, stable and pH-universal catalyst for electrochemical hydrogen production显示文摘High-performance nanomaterial catalysts for hydrogen evolution reaction via electrochemical water splitting are significant to the development of hydrogen energy.In this work,we report a robust and highly active catalyst fabricated through direct electrochemical deposition of Pt nanodendrites at the surface of activated carbon(Pt NDs).Owing to the large elect roc he mically active area and the exposed(111) facet of Pt,Pt NDs exhibits outstanding activity towards hydrogen evolution reaction with a low requiring overpotential of 0.027 V at 10 mA/cm2 and Tafel slope of ≈22 mV/dec in acidic media.In addition,the hydrogen yield of Pt NDs is 30%-45% larger than that of commercial Pt/C at the same Pt loadings.Moreover,Pt NDs exhibits excellent lo ng-term durability whose hydrogen production efficiency remains unchanged after six-hour hydrogen production,while the efficiency of commercial Pt/C catalyst decayed 9% under the same circumstance.Considering the superiority of catalytic activity and stability,this Pt NDs present great potentiality towards practical hydrogen production application. | Huifang Sun Qi Zeng Chen Ye Yangguang Zhu Feiyue Chen Mingyang Yang Li Fu Shiyu Du Jinhong Yu Nan Jiang Jianxiong Liu Tianzhun Wu Cheng-Te Lin | 2020 | Chinese Chemical Letters2020，31，9： | 0 |
| 14 | Metasurface-enabled polarization-independent LCoS spatial light modulator for 4K resolution and beyond显示文摘With the distinct advantages of high resolution,small pixel size,and multi-level pure phase modulation,liquid crystal on silicon(LCoS)devices afford precise and reconfigurable spatial light modulation that enables versatile applications ranging from micro-displays to optical communications.However,LCoS devices suffer from a long-standing problem of polarization-dependent response in that they only perform phase modulation on one linear polarization of light,and polarization-independent phase modulation-essential for most applications-have had to use complicated polarization-diversity optics.We propose and demonstrate,for the first time,an LCos device that directly achieves high-performance polarization-independent phase modulation at telecommunication wavelengths with 4K resolution and beyond by embedding a polarization-rotating metasurface between the LCoS backplane and the liquid crystal phase-modulating layer.We verify the device with a number of typical polarization-independent application functions including beam steering,holographical display,and in a key optical switching element-wavelength selective switch(WsS),demonstrating the significant benefits in terms of both configuration simplification and performance improvement. | Zhaoxiang Zhu Yuanhui Wen Jiagi Li Yujie Chen Zenghui Peng Jianxiong Liz Lei Zhu Yunfei Wu Lidan Zhou Lin Liu Liangjia Zong Siyuan Yu | 2023 | Light(Science & Applications)2023，12，7： | 0 |
| 15 | Roadmap for rechargeable batteries:present and beyond显示文摘Rechargeable batteries currently hold the largest share of the electrochemical energy storage market,and they play a major role in the sustainable energy transition and industrial decarbonization to respond to global climate change.Due to the increased popularity of consumer electronics and electric vehicles,lithium-ion batteries have quickly become the most successful rechargeable batteries in the past three decades,yet growing demands in diversified application scenarios call for new types of rechargeable batteries.Tremendous efforts are made to developing the next-generation post-Li-ion rechargeable batteries,which include,but are not limited to solid-state batteries,lithium–sulfur batteries,sodium-/potassium-ion batteries,organic batteries,magnesium-/zinc-ion batteries,aqueous batteries and flow batteries.Despite the great achievements,challenges persist in precise understandings about the electrochemical reaction and charge transfer process,and optimal design of key materials and interfaces in a battery.This roadmap tends to provide an overview about the current research progress,key challenges and future prospects of various types of rechargeable batteries.New computational methods for materials development,and characterization techniques will also be discussed as they play an important role in battery research. | Sen Xin Xu Zhang Lin Wang Haijun Yu Xin Chang Yu-Ming Zhao Qinghai Meng Pan Xu Chen-Zi Zhao Jiahang Chen Huichao Lu Xirui Kong Jiulin Wang Kai Chen Gang Huang Xinbo Zhang Yu Su Yao Xiao Shu-Lei Chou Shilin Zhang Zaiping Guo Aobing Du Guanglei Cui Gaojing Yang Qing Zhao Liubing Dong Dong Zhou Feiyu Kang Hu Hong Chunyi Zhi Zhizhang Yuan Xianfeng Li Yifei Mo Yizhou Zhu Dongfang Yu Xincheng Lei Jianxiong Zhao Jiayi Wang Dong Su Yu-Guo Guo Qiang Zhang Jun Chen Li-Jun Wan | 2024 | Science China Chemistry2024，67，1： | 0 |
| 16 | Development of a masticatory robot using a novel cable-driven linear actuator with bidirectional motion显示文摘Masticatory robots are an effective in vitro performance testing device for dental material and mandibular prostheses.A cable-driven linear actuator(CDLA)capable of bidirectional motion is proposed in this study to design a masticatory robot that can achieve increasingly human-like chewing motion.The CDLA presents remarkable advantages,such as lightweight and high stiffness structure,in using cable amplification and pulley systems.This work also exploits the proposed CDLA and designs a masticatory robot called Southeast University masticatory robot(SMAR)to solve existing problems,such as bulky driving linkage and position change of the muscle’s origin.Stiffness analysis and performance experiment validate the CDLA’s efficiency,with its stiffness reaching 1379.6 N/mm(number of cable parts n=4),which is 21.4 times the input wire stiffness.Accordingly,the CDLA’s force transmission efficiencies in two directions are 84.5%and 85.9%.Chewing experiments are carried out on the developed masticatory robot to verify whether the CDLA can help SMAR achieve a natural human-like chewing motion and sufficient chewing forces for potential applications in performance tests of dental materials or prostheses. | Haiying WEN Jianxiong ZHU Hui ZHANG Min DAI Bin LI Zhisheng ZHANG Weiliang XU Ming CONG | 2022 | Frontiers of Mechanical Engineering2022，17，4： | 0 |
| 17 | Network Pharmacology-based Strategy for Predicting Active Ingredients and Potential Targets of Cuscutae semen and Lycii fructus in Spermatogenic Dysfunction显示文摘Background:Traditional Chinese Medicine(TCM)Cuscutae semen(SC,Tusizi from Cuscuta chinensis Lam.)and Lycii fructus(FL,Gouqi from Lycium barbarum L.),are also used as a herb pair(SC-FL)to treat various ailments,including spermatogenic dysfunction(SD),a disease responsible for low fertility in males.Objective:Herein,we will further determine the bioactive components,component targets and partial molecular mechanisms of the herb pair for the treatment of SD.Methods:We employed the traditional Chinese medicine systems pharmacology database in combination with Ultra high performance liquid chromatography(UHPLC)analysis to analyze the active ingredients of the SC-FL herbal pair and explore its possible targets and underlying mechanism in treatment of spermatogenic dysfunction(SD).Moreover,we used a Sprague-Dawley rat model,generated by using glucosides of Tripterygium wilfordii(GTW),to evaluate the effect of SC-FL and the underlying mechanism on SD and reliability of certain key targets and pathways obtained from the pharmacology analysis.Results:We identified 56 active ingredients in SC-LF affecting 41 overlapping gene signals that influenced SD treatment outcomes.262 Gene Ontology(GO)terms and 170 pathways were yielded under analyses of Gene Ontology,Kyoto Encyclopedia of Gene and Genome pathway from which we predicted that cell proliferation and apoptosis were the primary biological processes(BP)involved in the treatment of SD by SC-LF.The results showed that SC-FL treatment significantly improved the testicular organ coefficient along with sperm count and motility,while reduced testicular damage and testicular tissue cell apoptosis in SD model.Mechanistically,SC-FL significantly upregulated the expression levels of anti-apoptotic proteins AR and BCL2 and downregulated those of pro-apoptotic proteins BAD,BAX,cleaved caspase 3,and CASP3.Conclusion:Collectively,these results indicated that SC-FL elicited a protective effect by potentially regulating apoptosis,thus suggesting that it will represent an effective reagent for male infertility. | Jianxiong Ma Siqi Guan Yutian Zhu Lei Dong Xiting Wang Wangqiang Chen Caifei Ding Bodong Lv Hongxuan Tong | 2022 | Clinical Complementary Medicine and Pharmacology2022，2，4： | 0 |
| 18 | Classification of Principal Wood Species in China Based on the Physiomechanical Properties显示文摘Many tree species are planted in China with variable properties and usage.Toward exploring the structure-properties relationships of wood and classifying the species more reasonably,the physiomechanical properties of the domestic wood species in China were analyzed statistically.According to the correlation analysis,the mechanical properties were closely related to the wood density.Except impact toughness and cleavage strength,the correlation coefficients between mechanical properties and densities were more than 0.8.However,shrinkage properties showed fewer correlations with densities,and the coefficient was no more than 0.7.Primary component analysis was proved to be feasible to explore the information of the physiomechanical properties.Two principal components(PC1 and PC2)could account for most of the information.PC1 and PC2 were designated as density-dominated and shrinkage-associated factors,respectively.The domestic wood species in China could be classified into 4 clusters based on their physiomechanical properties.According to the cluster results,reasonable grading was proposed for air-dried density,volume shrinkage,modulus of rupture,compression strength parallel to grain and hardness in cross section.The statistical results brought insights into analyzing the physiomechanical properties of domestic Chinese wood species,which was helpful for developing strategies of tree breeding and technologies of wood processing. | Jianyi Zhu Hui Peng Xiaoning Lu Jianxiong Lyu Tianyi Zhan | 2023 | Journal of Renewable Materials2023，11，3： | 0 |
| 19 | Rosuvastatin suppresses TNF-α-induced matrix catabolism,pyroptosis and senescence via the HMGB1/NF-κB signaling pathway in nucleus pulposus cells显示文摘Intervertebral disc degeneration is mainly caused by irregular matrix metabolism in nucleus pulposus cells and involves inflammatory factors such as TNF-α.Rosuvastatin,which is widely used in the clinic to reduce cholesterol levels,exerts anti-inflammatory effects,but whether rosuvastatin participates in IDD remains unclear.The current study aims to investigate the regulatory effect of rosuvastatin on IDD and the potential mechanism.In vitro experiments demonstrate that rosuvastatin promotes matrix anabolism and suppresses catabolism in response to TNF-αstimulation.In addition,rosuvastatin inhibits cell pyroptosis and senescence induced by TNF-α.These results demonstrate the therapeutic effect of rosuvastatin on IDD.We further find that HMGB1,a gene closely related to cholesterol metabolism and the inflammatory response,is upregulated in response to TNF-αstimulation.HMGB1 inhibition or knockdown successfully alleviates TNF-α-induced ECM degradation,senescence and pyroptosis.Subsequently,we find that HMGB1 is regulated by rosuvastatin and that its overexpression abrogates the protective effect of rosuvastatin.We then verify that the NF-κB pathway is the underlying pathway regulated by rosuvastatin and HMGB1.In vivo experiments also reveal that rosuvastatin inhibits IDD progression by alleviating pyroptosis and senescence and downregulating HMGB1 and p65.This study might provide new insight into therapeutic strategies for IDD. | Weijian Chen Zhihuai Deng Jianxiong Zhu Liang Yuan Shuangxing Li Yangyang Zhang Jiajun Wu Zhengqi Huang Tianyu Qin Wei Ye | 2023 | Acta Biochimica et Biophysica Sinica2023，55，5： | 0 |
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