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36篇 您的检索式:作者名="JingQin"
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1In vivo theranostics with near-infraredemitting carbon dots—highly efficient photothermal therapy based on passive targeting after intravenous administration显示文摘Carbon dots that exhibit near-infrared fluorescence(NIR CDs)are considered emerging nanomaterials for advanced biomedical applications with low toxicity and superior photostability and targeting compared to currently used photoluminescence agents.Despite progress in the synthesis of NIR CDs,there remains a key obstacle to using them as an in vivo theranostic agent.This work demonstrates that the newly developed sulfur and nitrogen codoped NIR CDs are highly efficient in photothermal therapy(PTT)in mouse models(conversion efficiency of 59%)and can be readily visualized by photoluminescence and photoacoustic imaging.The real theranostic potential of NIR CDs is enhanced by their unique biodistribution and targeting.Contrary to all other nanomaterials that have been tested in biomedicine,they are excreted through the body’s renal filtration system.Moreover,after intravenous injection,NIR CDs are accumulated in tumor tissue via passive targeting,without any active species such as antibodies.Due to their accumulation in tumor tissue without the need for intratumor injection,high photothermal conversion,excellent optical and photoacoustic imaging performance,and renal excretion,the developed CDs are suitable for transfer to clinical biomedical practice.Xin Bao Ye Yuan Jingqin Chen Bohan Zhang Di Li Ding Zhou Pengtao Jing Guiying Xu Yingli Wang Kateřina Holá Dezhen Shen Changfeng Wu Liang Song Chengbo Liu Radek Zbořil Songnan Qu 2018Light(Science & Applications)2018,7,1:13
2Laser performance of the SG-Ⅲ laser facility显示文摘SG-Ⅲ laser facility is now the largest laser driver for inertial confinement fusion research in China. The whole laser facility can deliver 180 kJ energy and 60 TW power ultraviolet laser onto target, with power balance better than 10%.We review the laser system and introduce the SG-Ⅲ laser performance here.Wanguo Zheng Xiaofeng Wei Qihua Zhu Feng Jing Dongxia Hu Jingqin Su Kuixing Zheng Xiaodong Yuan Hai Zhou Wanjun Dai Wei Zhou Fang Wang Dangpeng Xu Xudong Xie Bin Feng Zhitao Peng Liangfu Guo Yuanbin Chen Xiongjun Zhang Lanqin Liu Donghui Lin Zhao Dang Yong Xiang Xuewei Deng 2016High Power Laser Science and Engineering2016,4,3:13
3A new contact material—Ag/SnO_2-La_2O_3-Bi_2O_3显示文摘A super-fine compound powder,Ag/SnO2+La2O3+Bi2O3,has been obtained using the chemical coprecipitation method.And a new contact material,Ag/SnO2+La2O3+Bi2O3,was produced by the powder metallurgy method.Its properties are as follows:the density is 9.75-9.93g/cm^3,the resistivity is 2.31-2.55μΩ.cm.the hardness is 880-985 MPa.Its microstructure shows that the fine oxides have a uniform distribution in the silver matrix.The results of make-break capacity and temperature rise testing show that the new material has better ability of anti-arc erosion and lower temperature rise than that of commonly used Ag/CdO.LU Jianguo, WANG Jingqin, ZHAO Jingying, WEN Ming, WANG Baozhu, and WANG XiaohongInstitute of Electrical Apparatus, Hebei University of Technology, Tianjin, 300130, China 2002Rare Metals2002,21,4:12
4Highly Sensitive MoS_2–Indocyanine Green Hybrid for Photoacoustic Imaging of Orthotopic Brain Glioma at Deep Site显示文摘Photoacoustic technology in combination with molecular imaging is a highly effective method for accurately diagnosing brain glioma. For glioma detection at a deeper site, contrast agents with higher photoacoustic imaging sensitivity are needed. Herein, we report a MoS_2–ICG hybrid with indocyanine green(ICG) conjugated to the surface of MoS_2 nanosheets. The hybrid significantly enhanced photoacoustic imaging sensitivity compared to MoS_2 nanosheets. This conjugation results in remarkably high optical absorbance across a broad near-infrared spectrum, redshifting of the ICG absorption peak and photothermal/photoacoustic conversion efficiency enhancement of ICG. A tumor mass of 3.5 mm beneath the mouse scalp was clearly visualized by using MoS_2–ICG as a contrast agent for the in vivo photoacoustic imaging of orthotopic glioma, which is nearly twofold deeper than the tumors imaged in our previous report using MoS_2 nanosheet. Thus, combined with its good stability and high biocompatibility, the MoS_2–ICG hybrid developed in this study has a great potential for high-efficiency tumor molecular imaging in translational medicine.Chengbo Liu Jingqin Chen Ying Zhu Xiaojing Gong Rongqin Zheng Ningbo Chen Dong Chen Huixiang Yan Peng Zhang Hairong Zheng Zonghai Sheng Liang Song 2018Nano-Micro Letters2018,10,3:10
5First-principles study of lithium intercalated bilayer graphene显示文摘Lithium intercalated bilayer graphene has been investigated using first-principles density functional theory calculations. Results show that there exist AB and AA stacking sequences for bilayer graphene in which the latter is more favorable for the Li storage and the former will evolve into the latter with the intercalation of Li ions. The relationship between the interlayer distance of two graphene sheets and the intercalated capacity of Li ions is discussed. It is found that structural defect is identified to store Li ions more favorably than pristine bilayer graphene and an isolated C atom vacancy in bilayer graphene can capture three Li ions between two graphene sheets.ZHOU JingJing ZHOU WeiWei GUAN ChunMei SHEN JingQin OUYANG ChuYing LEI MinSheng SHI SiQi TANG WeiHua 2012Science China(Physics,Mechanics & Astronomy)2012,55,8:4
6A comparative investigation into floatability of bastnaesite with three di/trialkyl phosphate surfactants显示文摘Flotation separation and recovery of rare earth minerals(REM) have returned to an important position due to the growing strategy demand for rare earth elements(REE).In this paper,a comparative investigation into the floatability of bastnaesite((Ce,La)FCO3) was conducted by using three di/trialkyl phosphate collectors,di(2-ethylhexyl) phosphate(DEHPA),dibutyl phosphate(DBP) and tributyl phosphate(TBP).The density functional theory(DFT) computation recommends that the chemical activity of the three phosphate collectors is in order of DEHPA≥ DBP >> TBP,and their hydrophobization assuggested by the IgP(oil-water partition coefficient) value is in the order of DEHPA> TBP> DBP.The micro-flotation indicates that the preferable pH values for flotation of bastnaesite with the three phosphate collectors are 7.0-8.0,and DEHPA achieves much higher flotation recovery of bastnaesite,followed by DBP,and then TBP,which coincides with their reactivity and hydrophobicity,the two prerequisites for froth flotation.The contact angle,zeta potential,Fourier transform infrared spectroscopy(FTIR) and X-ray photoelectron spectroscopy(XPS) deduce that DEHPA likely reacts with the Ce(Ⅲ)atoms of bastnaesite interface through its O atom(s) of the P(=O)-O-group to generate the Ce-O-P bonds,and its two 2-ethylhexyl groups orient outside for attaching bubbles,resulting in flotation enrichment of bastnaesite.Furthermore,this investigation offers a novel strategy for developing collectors in selective beneficiation of REM.Hongli Fan Xianglin Yang Jing Qi Guangyi Liu Jingqin Qin 2021Journal of Rare Earths2021,39,11:3
7Progress in octahedral spherical hohlraum study显示文摘In this paper,we give a review of our theoretical and experimental progress in octahedral spherical hohlraum study.From our theoretical study,the octahedral spherical hohlraums with 6 Laser Entrance Holes(LEHs)of octahedral symmetry have robust high symmetry during the capsule implosion at hohlraum-to-capsule radius ratio larger than 3.7.In addition,the octahedral spherical hohlraums also have potential superiority on low backscattering without supplementary technology.We studied the laser arrangement and constraints of the octahedral spherical hohlraums,and gave a design on the laser arrangement for ignition octahedral hohlraums.As a result,the injection angle of laser beams of 50°-60°was proposed as the optimum candidate range for the octahedral spherical hohlraums.We proposed a novel octahedral spherical hohlraum with cylindrical LEHs and LEH shields,in order to increase the laser coupling efficiency and improve the capsule symmetry and to mitigate the influence of the wall blowoff on laser transport.We studied on the sensitivity of the octahedral spherical hohlraums to random errors and compared the sensitivity among the octahedral spherical hohlraums,the rugby hohlraums and the cylindrical hohlraums,and the results show that the octahedral spherical hohlraums are robust to these random errors while the cylindrical hohlraums are the most sensitive.Up till to now,we have carried out three experiments on the spherical hohlraum with 2 LEHs on Shenguang(SG)laser facilities,including demonstration of improving laser transport by using the cylindrical LEHs in the spherical hohlraums,spherical hohlraum energetics on the SGIII prototype laser facility,and comparisons of laser plasma instabilities between the spherical hohlraums and the cylindrical hohlraums on the SGIII laser facility.Ke Lan Jie Liu Zhichao Li Xufei Xie Wenyi Huo Yaohua Chen Guoli Ren Chunyang Zheng Dong Yang Sanwei Li Zhiwen Yang Liang Guo Shu Li Mingyu Zhang Xiaoying Han Chuanlei Zhai Lifei Hou Yukun Li Keli Deng Zheng Yuan Xiayu Zhan Feng Wang Guanghui Yuan Haijun Zhang Bobin Jiang Lizhen Huang Wei Zhang Kai Du Runchang Zhao Ping Li Wei Wang Jingqin Su Xuewei Deng Dongxia Hu Wei Zhou Huaiting Jia Yongkun Ding Wanguo Zheng Xiantu He 2016Matter and Radiation at Extremes2016,1,1:2
8The special shaped laser spot for driving indirect-drive hohlraum with multi-beam incidence显示文摘In indirect drive, reducing peak intensity of a single beam and controlling overlap of multi-beams are two opposite requirements for laser focal spot design. In this paper, an improved laser spot design technique for indirect drive built upon the geometric structures of laser propagation into hohlraum has been introduced. The proposed technique is able to generate appropriate continuous phase plate(CPP) producing a special shaped spot that can balance the opposite requirements. The corresponding CPP does not bring difficulties to the design and fabrication. Phase aberrations are more sensitive to the special shaped spot; however, it can be tolerable for the current beam control level.Ping Li Sai Jin Runchang Zhao Wei Wang Fuquan Li Mingzhong Li Jingqin Su Xiaofeng Wei 2017High Power Laser Science and Engineering2017,5,3:2
9Analysis on FM-to-AM conversion of SSD beam induced by etalon effect in a high-power laser system显示文摘FM-to-AM(frequency modulation-to-amplitude modulation)conversion caused by nonuniform spectral transmission of broadband beam is harmful to high-power laser facility.Smoothing by spectral dispersion(SSD)beam is a special broadband beam for its monochromatic feature at the given time and space on the near field.The traditional method which uses the optical spectral transfer function as filters cannot accurately describe its AM characteristics.This paper presents the theoretical analysis of the etalon effect for SSD beam.With a low-order approximation,the analytic model of the temporal shape of SSD beam is obtained for the first time,which gives the detailed AM characteristics at local and integral aspects,such as the variation of ripples width and amplitude in general situation.We also analyze the FM-to-AM conversion on the focal plane;in the focusing process,the lens simply acts as an integrator to smooth the AM of SSD beam.Because AM control is necessary for the near field to avoid optics damage and for the far field to ensure an optimal interaction of laser-target,our investigations could provide some important phenomena and rules for pulse shape control.Ping Li Wei Wang Jingqin Su Xiaofeng Wei 2019High Power Laser Science and Engineering2019,7,2:2
10Corrigendum to“First demonstration of improving laser propagation inside the spherical hohlraums by using the cylindrical laser entrance hole”[Matter Radiation Extremes 1(1)(2016)2-7]显示文摘Corrigendum Text:On page 2 of this letter,there is a misprint in the unit.The unit of the geometrical dimension of the spherical hohlraums on this page should always be“mm”rather than“mm”,i.e.in the second paragraph,“…with 800 J per beam at 0.35 mm…”should be“…with 800 J per beam at 0.35 mm…”,“The slit of 400 mm width is parallel…”should be“The slit of 400 mm width is parallel…”,“The laser focal diameter is about 500 mm…”should be“The laser focal diameter is about 500 mm…”;in the third paragraph,“…we take 850 mm as the radius…”should be“…we take 850 mm as the radius…”,“The LEH radius R_(L) is 400 mm…”should be“The LEH radius R_(L) is 400 mm…”,“…the radius of the cylindrical LEH outer ring is taken as 1.5 R_(L)=600 mm”should be“…the radius of the cylindrical LEH outer ring is taken as 1.5 R_(L)=600 mm”.This mistake does not affect any of the main results of the original letter.Wenyi Huo Zhichao Li Dong Yang Ke Lan Jie Liu Guoli Ren Sanwei Li Zhiwen Yang Liang Guo Lifei Hou Xuefei Xie Yukun Li Keli Deng Zheng Yuan Xiayu Zhan Guanghui Yuan Haijun Zhang Baibin Jiang Lizhen Huang Kai Du Runchang Zhao Ping Li Wei Wang Jingqin Su Yongkun Ding Xiantu He Weiyan Zhang 2016Matter and Radiation at Extremes2016,1,2:1
11Coding Gray-tone Mask For Refractive Microlens Fabrication显示文摘Jun YAO Jingqin SU Jinglei DU 2000Microelectronic Engineering2000,53,1:1
12Coding Gray-tone Mask For Refractive Microlens Fabrication显示文摘Jun YAO Jingqin SU Jinglei DU 2000Microelectronic Engineering2000,53,1:1
13Transarterial chemoembolisation (TACE) combined with endovascular implantation of an iodine-125 seed strand for the treatment of hepatocellular carcinoma with portal vein tumour thrombosis versus TACE alone: a two-arm, randomised clinical trial显示文摘MinJie Yang ZhuTing Fang ZhiPing Yan JianJun Luo LingXiao Liu Wen Zhang LinLin Wu JingQin Ma QingHui Yang QingXin Liu 2014Journal of Cancer Research and Clinical Oncology2014,,2:1
14Advances in the Pathogenesis of Perimenopausal Syndrome显示文摘Perimenopause syndrome refers to the syndrome of the disorders of multiple systems of women around menopause caused by the reduction in secreted estrogen and is also known as menopause syndrome.Its pathogenesis involves increasing age,the abatement of ovarian function,and psychological change caused by the increasing life pressure.The above factors lead to physical and mental changes in postmenopausal women.This paper summarizes the pathogenesis of perimenopause from the perspective of gene studies and existing experimental studies and provide some ideas for clinical treatment and research.Zhiyong Cao Ke Lu Jingqin Chen Gang Fang 2020Proceedings of Anticancer Research2020,4,3:1
15Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer显示文摘Sangjun Lee Sheila Stewart Iris Nagtegaal Jingqin Luo Yun Wu Graham Colditz Dan Medina D. Craig Allred 2012Cancer Research2012,,17:1
16Study on the behavior of silver rare earth oxide contact material显示文摘 Baozhu Wang Ming Wen 2000Proceedings of 46thIEEE Holm Conference of Electrical Contacts2000,,:1
17Nanoparticles of 5‐fluorouracil (5‐FU) loaded N‐succinyl‐chitosan (Suc‐Chi) for cancer chemotherapy: preparation, characterization — in‐vitro drug release and anti‐tumour activity显示文摘ChengyunYan DaweiChen JiweiGu JingQin 2010Journal of Pharmacy and Pharmacology2010,,9:1
18Study on the behavior of silver rare earth oxide contact material显示文摘Wang Jingqin Wang Baozhu Wen Ming 1996IEEE1996,19,3:1
19P2X 7 R suppression promotes glioma growth through epidermal growth factor receptor signal pathway显示文摘Jingqin Fang Xiao Chen Letian Zhang Jinhua Chen Yi Liang Xue Li Jianbo Xiang Lili Wang Guangkuo Guo Bo Zhang Weiguo Zhang 2013International Journal of Biochemistry and Cell Bi2013,,:1
20Free radicals, antioxidant defense systems, and schizophrenia 显示文摘WU JINGQIN KOSTEN T R ZHANG XIANGYANG 2013Progress in Neuro - psychopharmacol & Biological Psychiatry2013,46,:1
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