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| 1 | Pm21 from Haynaldia villosa Encodes a CC-NBS- LRR Protein Conferring Powdery Mildew Resistance in Wheat显示文摘 | Liping Xing Ping Hu Jiaqian Liu Kamil Witek Shuang Zhou Jiefei Xu Weihao Zhou Li Gao Zhenpu Huang Ruiqi Zhang Xiue Wang Peidu Chen Haiyan Wang Jonathan D.G. Jones Miroslava Karafiatova Jan Vrana Jan Baros Jaroslav Dolezel Yuanchun Tian Yufeng Wu Aizhong Cao | 2018 | Molecular Plant2018，11，6： | 16 |
| 2 | Optical meta-waveguides for integrated photonics and beyond显示文摘The growing maturity of nanofabrication has ushered massive sophisticated optical structures available on a photonic chip.The integration of subwavelength-structured metasurfaces and metamaterials on the canonical building block of optical waveguides is gradually reshaping the landscape of photonic integrated circuits,giving rise to numerous metawaveguides with unprecedented strength in controlling guided electromagnetic waves.Here,we review recent advances in meta-structured waveguides that synergize various functional subwavelength photonic architectures with diverse waveguide platforms,such as dielectric or plasmonic waveguides and optical fibers.Foundational results and representative applications are comprehensively summarized.Brief physical models with explicit design tutorials,either physical intuition-based design methods or computer algorithms-based inverse designs,are cataloged as well.We highlight how meta-optics can infuse new degrees of freedom to waveguide-based devices and systems,by enhancing light-matter interaction strength to drastically boost device performance,or offering a versatile designer media for manipulating light in nanoscale to enable novel functionalities.We further discuss current challenges and outline emerging opportunities of this vibrant field for various applications in photonic integrated circuits,biomedical sensing,artificial intelligence and beyond. | Yuan Meng Yizhen Chen Longhui Lu Yimin Ding Andrea Cusano Jonathan A.Fan Qiaomu Hu Kaiyuan Wang Zhenwei Xie Zhoutian Liu Yuanmu Yang Qiang Liu Mali Gong Qirong Xiao Shulin Sun Minming Zhang Xiaocong Yuan Xingjie Ni | 2021 | Light(Science & Applications)2021，10，12： | 6 |
| 3 | The miR319-Targeted GhTCP4 Promotes the Transition from Cell Elongation to Wall Thickening in Cotton Fiber显示文摘Plant cell growth involves a complex interplay among cell-wall expansion, biosynthesis, and, in specific tissues, secondary cell wall (SCW) deposition, yet the coordination of these processes remains elusive. Cotton fiber cells are developmentally synchronous, highly elongated, and contain nearly pure cellulose when mature. Here, we report that the transcription factor GhTCP4 plays an important role in balancing cotton fiber cell elongation and wall synthesis. During fiber development the expression of miR319 declines while GhTCP4 transcript levels increase, with high levels of the latter promoting SCW deposition. GhTCP4 interacts with a homeobox-containing factor, GhHOX3, and repressing its transcriptional activity. GhTCP4 and GhHOX3 function antagonistically to regulate cell elongation, thereby establishing temporal control of fiber cell transition to the SCW stage. We found that overexpression of GhTCP4A upregulated and accelerated activation of the SCW biosynthetic pathway in fiber cells, as revealed by transcriptome and promoter activity analyses, resulting in shorter fibers with varied lengths and thicker walls. In contrast, GhTCP4 downregulation led to slightly longer fibers and thinner cell walls. The GhHOX3–GhTCP4 complex may represent a general mechanism of cellular development in plants since both are conserved factors in many species, thus providing us a potential molecular tool for the design of fiber traits. | Jun-Feng Cao Bo Zhao Chao-Chen Huang Zhi-Wen Chen Ting Zhao Hong-Ru Liu Guan-Jing Hu Xiao-Xia Shangguan Chun-Min Shan- Ling-Jian Wang Tian-Zhen Zhang Jonathan F.Wendel Xue-Ying Guan Xiao-Ya Chen | 2020 | Molecular Plant2020，13，7： | 4 |
| 4 | Altered chromatin recruitment by FOXA1 mutations promotes androgen independence and prostate cancer progression显示文摘Dear Editor,F0XA1,a forkhead(FKHD)family transcription factor,is highly expressed in the epithelium of endoderm-derived organs, including the prostate gland.1 Transgenic mouse studies have shown that F0XA1 expression is required for prostate epithelial cell differentiation and ductal morphogenesis during development and for the maintenance of this differentiated epithelial phenotype in the adult. Mechanistically, F0XA1 binds FKHD motifs in the DNA to open chromatin and in crease local accessibility. | Bohan Xu Bing Song Xiaodong Lu Jung Kim Ming Hu Jonathan C.Zhao Jindan Yu | 2019 | Cell Research2019，29，9： | 4 |
| 5 | Experimental Gaussian Boson sampling显示文摘Gaussian Boson sampling(GBS) provides a highly efficient approach to make use of squeezed states from parametric down-conversion to solve a classically hard-to-solve sampling problem. The GBS protocol not only significantly enhances the photon generation probability, compared to standard Boson sampling with single photon Fock states, but also links to potential applications such as dense subgraph problems and molecular vibronic spectra. Here, we report the first experimental demonstration of GBS using squeezed-state sources with simultaneously high photon indistinguishability and collection efficiency.We implement and validate 3-, 4- and 5-photon GBS with high sampling rates of 832, 163 and 23 kHz,respectively, which is more than 4.4, 12.0, and 29.5 times faster than the previous experiments.Further, we observe a quantum speed-up on a NP-hard optimization problem when comparing with simulated thermal sampler and uniform sampler. | Han-Sen Zhong Li-Chao Peng Yuan Li Yi Hu Wei Li Jian Qin Dian Wu Weijun Zhang Hao Li Lu Zhang Zhen Wang Lixing You Xiao Jiang Li Li Nai-Le Liu Jonathan P.Dowling Chao-Yang Lu Jian-Wei Pan | 2019 | Science Bulletin2019，64，8： | 3 |
| 6 | 2D-ultrathin MXene/DOXjade platform for iron chelation chemo-photothermal therapy显示文摘An increased demand for iron is a hallmark of cancer cells and is thought necessary to promote high cell proliferation,tumor progression and metastasis.This makes iron metabolism an attractive therapeutic target.Unfortunately,current iron-based therapeutic strategies often lack effectiveness and can elicit off-target toxicities.We report here a dual-therapeutic prodrug,DOXjade,that allows for iron chelation chemo-photothermal cancer therapy.This prodrug takes advantage of the clinically approved iron chelator deferasirox(ExJade®)and the topoisomerase 2 inhibitor,doxorubicin(DOX).Loading DOXjade onto ultrathin 2D Ti_(3)C_(2) MXene nanosheets produces a construct,Ti_(3)C_(2)-PVP@DOXjade,that allows the iron chelation and chemotherapeutic functions of DOXjade to be photo-activated at the tumor sites,while potentiating a robust photothermal effect with photothermal conversion efficiencies of up to 40%.Antitumor mechanistic investigations reveal that upon activation,Ti_(3)C_(2)-PVP@DOXjade serves to promote apoptotic cell death and downregulate the iron depletion-induced iron transferrin receptor(TfR).A tumor pH-responsive iron chelation/photothermal/chemotherapy antitumor effect was achieved both in vitro and in vivo.The results of this study highlight what may constitute a promising iron chelation-based phototherapeutic approach to cancer therapy. | Yunjie Xu Yingwei Wang Jusung An Adam C.Sedgwick Mingle Li Jianlei Xie Weibin Hu Jianlong Kang Sajal Sen Axel Steinbrueck Bin Zhang Lijun Qiao Swelm Wageh Jonathan F.Arambula Liping Liu Han Zhang Jonathan L.Sessler Jong Seung Kim | 2022 | Bioactive Materials2022，7，8： | 2 |
| 7 | Flat-gain fiber Raman amplifiers using equally spaced pumps显示文摘 | Jonathan Hu Brian S Marks Curtis P Menyuk | 2004 | Journal of Lightwave Technology2004，22，： | 1 |
| 8 | Establishment and characterization of a human non-small cell lung cancercell line显示文摘 | Amy Tai Yan Fang Jonathan Sham Wen Deng Liang Hu Dan Xie George Tsao Annie Cheung Xin-yuan Guan | 2005 | Oncology Reports2005，，6： | 1 |
| 9 | Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP显示文摘 | Min Lu Hilde Breyssens Victoria Salter Shan Zhong Ying Hu Caroline Baer Indrika Ratnayaka Alex Sullivan Nicholas R. Brown Jane Endicott Stefan Knapp Benedikt M. Kessler Mark R. Middleton Christian Siebold E. Yvonne Jones Elena V. Sviderskaya Jonathan Cebo | 2013 | Cancer Cell2013，，5： | 1 |
| 10 | 2021年ISHNE/HRS/EHRA/APHRS关于移动医疗心律失常管理共识:心脏节律专业人员的数字医疗工具显示文摘国际动态心电图和无创心电图学会/心律学会/欧洲心律协会/亚太心律协会制定的'关于移动医疗心律失常管理共识'描述了移动医疗(mHealth)技术在心律失常管理中的现状,涉及数字医疗工具范围,以及可能应用于心律失常的诊断和协助临床决策。合并症和生活方式管理(日益公认在心律失常中起作用)以及患者自我管理赋予了mHealth新的内容。共识对预测分析的承诺,以及嵌入了mHealth的常规临床关怀的操作面临的挑战,进行了探讨。 | Niraj Varma Iwona Cygankiewicz Mintu Turakhia Hein Heidbuchel Yufeng Hu Lin Yee Chen Jean-Philippe Couderc Edmond M.Cronin Jerry D.Estep Lars Grieten Deirdre A.Lane Reena Mehra Alex Page Rod Passman Jonathan Piccini Ewa Piotrowicz Ryszard Piotrowicz Pyotr G.Platonov Antonio Luiz Ribeiro Robert E.Rich Andrea M.Russo David Slotwiner Jonathan S.Steinberg Emma Svennberg 蔡星星(翻译) 陈牧(翻译) 陈泰中(翻译) 费聿东(翻译) 费振涛(翻译) 龚畅祺(翻译) 胡晓亮(翻译) 李澄(翻译) 练小铭(翻译) 莫斌峰(翻译) 王海成(翻译) 王倩(翻译) 卫郅星(翻译) 徐全福(翻译) 杨眉(翻译) 杨钰粒(翻译) 于怡驰(翻译) 张睿(翻译) 赵铭哲(翻译) 赵晏(翻译) 李毅刚(审校) 王群山(审校) | 2021 | 中国心脏起搏与心电生理杂志2021，35，2： | 1 |
| 11 | Relationship between osseointegration and superelastic biomechanics in porous NiTi scaffolds显示文摘 | Xiangmei Liu Shuilin Wu Kelvin W.K. Yeung Y.L. Chan Tao Hu Zushun Xu Xuanyong Liu Jonathan C.Y. Chung Kenneth M.C. Cheung Paul K. Chu | 2010 | Biomaterials2010，，2： | 1 |
| 12 | Correlation of AIB1 overexpression with advanced clinical stage of human colorectal carcinoma显示文摘 | Dan Xie Jonathan S.T. Sham Wei-Fen Zeng Han-Liang Lin Jiong Bi Li-Hong Che Liang Hu Yi-Xin Zeng Xin-Yuan Guan | 2005 | Human Pathology2005，，7： | 1 |
| 13 | Epipolar resampling of linear pushbroom satellite imagery by a new epipolarity model显示文摘 | Mi Wang Fen Hu Jonathan Li | 2011 | ISPRS Journal of Photogrammetry and Remote Sensing2011，，3： | 1 |
| 14 | Perfluorinated compounds in surface waters from Northern China: Comparison to level of industrialization显示文摘 | Tieyu Wang Jong Seong Khim Chunli Chen Jonathan E. Naile Yonglong Lu Kurunthachalam Kannan Jinsoon Park Wei Luo Wentao Jiao Wenyou Hu John P. Giesy | 2011 | Environment International2011，，： | 1 |
| 15 | PAHs in surface sediments from coastal and estuarine areas of the northern Bohai and Yellow Seas, China显示文摘 | Wentao Jiao Tieyu Wang Jong Khim Wei Luo Wenyou Hu Jonathan Naile John Giesy Yonglong Lu | 2012 | Environmental Geochemistry and Health2012，，4： | 1 |
| 16 | In silico directed mutagenesis identifies the CD 81/claudin‐1 hepatitis C virus receptor interface显示文摘 | Christopher Davis Helen J. Harris Ke Hu Heidi E. Drummer Jane A. McKeating Jonathan G. L. Mullins Peter Balfe | 2012 | Cell Microbiol2012，，12： | 1 |
| 17 | Flat-Gain Fiber Raman Amplifers Using Equally Spaced Pumps 显示文摘 | HU JONATHAN MARKS B S MENYUK C R | 2004 | Journal of Lightwave Technology2004，22，6： | 1 |
| 18 | A porcine collagen-derived matrix as a carrier for recombinant human bone morphogenetic protein-2 enhances spinal fusion in rats显示文摘 | Masashi Miyazaki Yuichiro Morishita Wubing He Ming Hu Chananit Sintuu Henry J. Hymanson Jonathan Falakassa Hiroshi Tsumura Jeffrey C. Wang | 2009 | The Spine Journal2009，，1： | 1 |
| 19 | Flat-Gain Fiber Raman Amplifiers Using Equally Spaced Pumps 显示文摘 | HU JONATHAN MARKS B S MENYUK C R | 2004 | Journal Of Lightwave Technology2004，22，6： | 1 |
| 20 | Laboratory Analog and Numerical Study of Groundwater Flow and Solute Transport in A Karst Aquifer with Conduit and Matrix Domains 显示文摘 | Faulkner Jonathan Hu Bill X Kish Stephen | 2009 | Journal of Contaminant Hydrology2009，110，12： | 1 |
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