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| 1 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 2 | Advances in graphene reinforced metal matrix nanocomposites:Mechanisms,processing,modelling,properties and applications显示文摘Graphene has been extensively explored to enhance functional and mechanical properties of metalmatrix nanocomposites for wide-range applications due to their superior mechanical,electrical and thermal properties.This article discusses recent advances of key mechanisms,synthesis,manufacture,modelling and applications of graphene metal matrix nanocomposites.The main strengthening mechanisms include load transfer,Orowan cycle,thermal mismatch,and refinement strengthening.Synthesis technologies are discussed including some conventional methods(such as liquid metallurgy,powdermetallurgy,thermal spraying and deposition technology)and some advanced processing methods(such as molecular-level mixing and friction stir processing).Analytical modelling(including phenomenological models,semi-empirical models,homogenization models,and self-consistent model)and numerical simulations(including finite elements method,finite difference method,and boundary element method)have been discussed for understanding the interface bonding and performance characteristics between graphene and different metal matrices(Al,Cu,Mg,Ni).Key challenges in applying graphene as a reinforcing component for the metal matrix composites and the potential solutions as well as prospectives of future development and opportunities are highlighted. | Wenge Chen Tao Yang Longlong Dong Ahmed Elmasry Jiulong Song Nan Deng Ahmed Elmarakbi Terence Liu Hai Bao Lv Yong Qing Fu | 2020 | Nanotechnology and Precision Engineering2020，3，4： | 4 |
| 3 | Synthesis of self-assembly BaTiO3 nanowire by sol-gel and microwave method 显示文摘 | FU Chunlin CAI Wei ZHOU Longlong | 2009 | Applied Surface Science2009，255，23： | 1 |
| 4 | Characterizing dynamic load propagation in cohesionless granular packing using force chain显示文摘When dynamic load is applied on a granular assembly,the time-dependent dynamic load and initial static load(such as gravity stress)act together on individual particles.In order to better understand how dynamic load triggers the micro-structure's evolution and furtherly the ensemble behavior of a granular assembly,we propose a criterion to recognize the major propagation path of dynamic load in 2D granular materials,called the“dynamic force chain”.Two steps are involved in recognizing dynamic force chains:(1)pick out particles with dynamic load larger than the threshold stress,where the attenuation of dynamic stress with distance is considered;(2)among which quasi-linear arrangement of three or more particles are identified as a force chain.The spatial distribution of dynamic force chains in indentation of granular materials provides a direct measure of dynamic load diffusion.The statistical evolution of dynamic force chains shows strong correlation with the indentation behaviors. | Longlong Fu Shunhua Zhou Yuexiao Zheng Li Zhuang | 2023 | Particuology2023，，10： | 0 |
| 5 | Inconsistent effect of dynamic load waveform on macro-and micro-scale responses of ballast bed characterized in individual cycle:a numerical study显示文摘Cyclic load is widely adopted in laboratory to simulate the effect of train load on ballast bed.The effectiveness of such load equivalence is usually testified by having similar results of key concerns of ballast bed,such as deformation or stiffness,while the consistency of particle scale characteristics under two loading patterns is rarely examined,which is insufficient to well-understand and use the load simplification.In this study,a previous laboratory model test of ballast bed under cyclic load is rebuilt using 3D discrete element method(DEM),which is validated by dynamic responses monitored by high-resolution sensors.Then,train load having the same magnitude and amplitude as the cyclic load is applied in the numerical model to obtain the statistical characteristics of inter-particle contact force and particle movements in ballast bed.The results show that particle scale responses under two loading patterns could have quite deviation,even when macro-scale responses of ballast bed under two loading patterns are very close.This inconsistency indicates that the application scale of the DEM model should not exceed the validation scale.Moreover,it is important to examine multiscale responses to validate the effectiveness of load simplification. | Longlong Fu Yuexiao Zheng Yongjia Qiu Shunhua Zhou | 2023 | Railway Engineering Science2023，31，4： | 0 |
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