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| 1 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 2 | Application of biochar-based materials in environmental remediation:from multi-level structures to specific devices显示文摘The development of biochar has triggered a hot-spot in various research fields including agriculture,energy,environment,and materials.Biochar-based materials provide a novel approach against environmental challenging issues.Considering the rapid development of biochar materials,this review serves as a valuable platform to summarize the recent progress on the theoretical investigation and engineering applications of biochar materials in environmental remediation.For a better understanding of the structure-application relationships,the structural properties of biochar from macroscopic and microscopic aspects are summarized.The multilevel structures including elements,phases,surface chemistry,and molecular are highlighted to elucidate the multi-functional properties of biochars.Sorption,catalysis,redox reaction,and biological activity of biochar are briefly illustrated,which influence the transport,transformation,and removal of organic and inorganic pollutants in the environments.According to the multi-level structures and structure-application relationships of biochar,specific biochar-based materials and devices have been designed for practical environmental application.The important progress on the functionalization and device of biochar-based materials,including magnetic biochars,2D and 3D biochar-based macrostructures,immobilized microorganism on biochar,and biochar-amended biofilters are highlighted.The environmental friendliness and sustainability of biochar-based materials,considering the whole cycle from synthesis to application,are evaluated. | Lun Lu Wentao Yu Yaofeng Wang Kun Zhang Xiaomin Zhu Yuecan Zhang Yajing Wu Habib Ullah Xin Xiao Baoliang Chen | 2020 | Biochar2020，2，1： | 11 |
| 3 | Impact of monsoonal climatic change on Holocene overbank flooding along Sushui River, middle reach of the Yellow River, China显示文摘 | Chun Chang Huang Jiangli Pang Xiaochun Zha Hongxia Su Yaofeng Jia Yizhi Zhu | 2007 | Quaternary Science Reviews2007，，17： | 2 |
| 4 | Abrasion resistance of biaxially oriented polypropylene films coated with nanocomposite hard coatings显示文摘 | Wang Jing Zhu Yaofeng Fu Yaqin | 2013 | Applied Surface Science2013，，： | 1 |
| 5 | Safety and Efficacy of Holmium Laser Resection for Primary Nonmuscle-Invasive Bladder Cancer Versus Transurethral Electroresection: Single-Center Experience显示文摘 | Yaofeng Zhu Xianzhou Jiang Jianping Zhang Weili Chen Benkang Shi Zhishun Xu | 2008 | Urology2008，，3： | 1 |
| 6 | Clinical observation on HoLRBT treatment of bladder tumor 显示文摘 | Yaofeng Zhu Jun Chen Xianzhou Jiang | 2010 | ShandongMed2010，50，6： | 1 |
| 7 | Part of decortication ameliorates dopamine depletion-induced striatal neuron lesions in rats显示文摘The degeneration of dopaminergic neurons can lead to the hyperexcitability of striatal neurons.The motor symptoms of Parkinson's disease(PD)are caused by striatal dopamine insufficiency.After degeneration of dopaminergic neurons,the reduction of corticostriatal glutamate can reestablish the balance of striatal neurons which leads to relieve the PD pathology process.However,the mechanisms that reduction of corticostriatal glutamate can relieve vulnerability of striatal neurons were unclear.With the Golgi staining and electron microscopic analysis,we found that reduction of corticostriatal glutamate that used to decorticate decrease in the total length of dendrites and the density of dendritic spines of the striatal neurons in 6-hydroxydopamine(6-OHDA)lesion-induced PD rat model.Moreover,we found that reduction of corticostriatal glutamate recovered mitochondrial membrane potential. | Zhu Yaofeng Zheng Xuefeng Wanlong Lei | 2021 | 解剖学杂志2021，44，S01： | 0 |
| 8 | RCache: A Read-Intensive Workload-Aware Page Cache for NVM Filesystem显示文摘Byte-addressable non-volatile memory(NVM),as a new participant in the storage hierarchy,gives extremely high performance in storage,which forces changes to be made on current filesystem designs.Page cache,once a significant mechanism filling the performance gap between Dynamic Random Access Memory(DRAM)and block devices,is now a liability that heavily hinders the writing performance of NVM filesystems.Therefore state-of-the-art NVM filesystems leverage the direct access(DAX)technology to bypass the page cache entirely.However,the DRAM still provides higher bandwidth than NVM,which prevents skewed read workloads from benefiting from a higher bandwidth of the DRAM and leads to sub-optimal performance for the system.In this paper,we propose RCache,a readintensive workload-aware page cache for NVM filesystems.Different from traditional caching mechanisms where all reads go through DRAM,RCache uses a tiered page cache design,including assigning DRAM and NVM to hot and cold data separately,and reading data from both sides.To avoid copying data to DRAM in a critical path,RCache migrates data from NVM to DRAM in a background thread.Additionally,RCache manages data in DRAM in a lock-free manner for better latency and scalability.Evaluations on Intel Optane Data Center(DC)Persistent Memory Modules show that,compared with NOVA,RCache achieves 3 times higher bandwidth for read-intensive workloads and introduces little performance loss for write operations. | TU Yaofeng ZHU Bohong YANG Hongzhang HAN Yinjun SHU Jiwu | 2023 | ZTE Communications2023，21，1： | 0 |
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