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| 1 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 2 | Optimization of air quantity regulation in mine ventilation networks using the improved differential evolution algorithm and critical path method显示文摘In mine ventilation networks, the reasonable airflow distribution is very important for the production safety and economy. Three basic problems of the natural, full-controlled and semi-controlled splitting were reviewed in the paper. Aiming at the high difficulty semi-controlled splitting problem, the general nonlinear multi-objectives optimization mathematical model with constraints was established based on the theory of mine ventilation networks. A new algorithm, which combined the improved differential evaluation and the critical path method(CPM) based on the multivariable separate solution strategy,was put forward to search for the global optimal solution more efficiently. In each step of evolution,the feasible solutions of air quantity distribution are firstly produced by the improved differential evolution algorithm, and then the optimal solutions of regulator pressure drop are obtained by the CPM.Through finite steps iterations, the optimal solution can be given. In this new algorithm, the population of feasible solutions were sorted and grouped for enhancing the global search ability and the individuals in general group were randomly initialized for keeping diversity. Meanwhile, the individual neighborhood in the fine group which may be closely to the optimal solutions were searched locally and slightly for achieving a balance between global searching and local searching, thus improving the convergence rate. The computer program was developed based on this method. Finally, the two ventilation networks with single-fan and multi-fans were solved. The results show that this algorithm has advantages of high effectiveness, fast convergence, good robustness and flexibility. This computer program could be used to solve large-scale generalized ventilation networks optimization problem in the future. | Chen Kaiyan Si Junhong Zhou Fubao Zhang Renwei Shao He Zhao Hongmei | 2015 | International Journal of Mining Science and Technology2015，25，1： | 15 |
| 3 | Characterization of 500 Chinese patients with cervical esophageal cancer by clinicopathological and treatment outcomes显示文摘Objective: There are no comprehensive studies on survival outcomes and optimal treatment protocols for cervical esophageal cancer(CEC), due to its rare clinical prevalence. Our objective was to determine the relationship between pathological characteristics, treatment protocols, and survival outcomes in Chinese CEC patients.Methods: A total of 500 Chinese CEC patients were selected from our 500,000 esophageal and gastric cardia carcinoma database(1973–2018). There were two main groups: patients treated with surgery, and patients receiving non-surgical treatments(radiotherapy, radiochemotherapy, and chemotherapy). The Chi-square test and Kaplan–Meier method were used to compare the continuous variables and survival.Results: Among the 500 CEC patients, 278(55.6%) were male, and the median age was 60.9 ± 9.4 years. A total of 496 patients(99.2%) were diagnosed with squamous cell carcinoma. In 171(34.2%) patients who received surgery, 22(12.9%) had undergone laryngectomy. In 322(64.4%) patients who received non-surgical treatments, 245(76.1%) received radiotherapy. Stratified survival analysis showed that only T stage was related with survival outcomes for CEC patients in the surgical group, and the outcomes between laryngectomy and non-laryngectomy patients were similar. It was noteworthy that the 5-year survival rate was similar in CEC patients among the different groups treated with surgery, radiotherapy, chemotherapy, or radiochemotherapy(P = 0.244). Conclusions: The CEC patients had similar survival outcomes after curative esophagectomy and radiotherapy, including those with or without total laryngectomy. These findings suggest that radiotherapy could be the initial choice for treatment of Chinese CEC patients. | Peinan Chen Xueke Zhao Fuyou Zhou Xin Song Shoujia Hu Yan Jin Xianzeng Wang Xuena Han ZongminFan Ran Wang Bei Li Wenli Han Panpan Wang Jilin Li Lixin Wan Liguo Zhang Qide Bao Fubao Chang Yanru Qin Zhiwei Chang Jianwei Ku Haijun Yang Ling Yuan Jingli Ren Xuemin Li Lidong Wang | 2020 | Cancer Biology & Medicine2020，17，1： | 6 |
| 4 | Chinese expert consensus on conversion therapy for hepatocellular carcinoma(2021 edition)显示文摘Recent advances in systemic and locoregional treatments for patients with unresectable or advanced hepatocellular carcinoma(HCC)have resulted in improved response rates.This has provided an opportunity for selected patients with initially unresectable HCC to achieve adequate tumor downstaging to undergo surgical resection,a‘conversion therapy’strategy.However,conversion therapy is a new approach to the treatment of HCC and its practice and treatment protocols are still being developed.Review the evidence for conversion therapy in HCC and develop consensus statements to guide clinical practice.Evidence review:Many research centers in China have accumulated significant experience implementing HCC conversion therapy.Preliminary findings and data have shown that conversion therapy represents an important strategy to maximize the survival of selected patients with intermediate stage to advanced HCC;however,there are still many urgent clinical and scientific challenges for this therapeutic strategy and its related fields.In order to summarize and learn from past experience and review current challenges,the Chinese Expert Consensus on Conversion Therapy for Hepatocellular Carcinoma(2021 Edition)was developed based on a review of preliminary experience and clinical data from Chinese and non-Chinese studies in this field and combined with recommendations for clinical practice.Sixteen consensus statements on the implementation of conversion therapy for HCC were developed.The statements generated in this review are based on a review of clinical evidence and real clinical experience and will help guide future progress in conversion therapy for patients with HCC. | Hui-Chuan Sun Jian Zhou Zheng Wang Xiufeng Liu Qing Xie Weidong Jia Ming Zhao Xinyu Bi Gong Li Xueli Bai Yuan Ji Li Xu Xiao-Dong Zhu Dousheng Bai Yajin Chen Yongjun Chen Chaoliu Dai Rongping Guo Wenzhi Guo Chunyi Hao Tao Huang Zhiyong Huang Deyu Li Gang Li Tao Li Xiangcheng Li Guangming Li Xiao Liang Jingfeng Liu Fubao Liu Shichun Lu Zheng Lu Weifu Lv Yilei Mao Guoliang Shao Yinghong Shi Tianqiang Song Guang Tan Yunqiang Tang Kaishan Tao Chidan Wan Guangyi Wang Lu Wang Shunxiang Wang Tianfu Wen Baocai Xing Bangde Xiang Sheng Yan Dinghua Yang Guowen Yin Tao Yin Zhenyu Yin Zhengping Yu Bixiang Zhang Jialin Zhang Shuijun Zhang Ti Zhang Yamin Zhang Yubao Zhang Aibin Zhang Haitao Zhao Ledu Zhou Wu Zhang Zhenyu Zhu Shukui Qin Feng Shen Xiujun Cai Gaojun Teng Jianqiang Cai Minshan Chen Qiang Li Lianxin Liu Weilin Wang Tingbo Liang Jiahong Dong Xiaoping Chen Xuehao Wang Shusen Zheng Jia Fan 无 | 2022 | Hepatobiliary Surgery and Nutrition2022，11，2： | 4 |
| 5 | Wind power forecasting error-based dispatch method for wind farm cluster显示文摘With the technical development of wind power forecasting,making wind power generation schedule in power systems become an inevitable tendency.This paper proposes a new dispatch method for wind farm(WF)cluster by considering wind power forecasting errors.A probability distribution model of wind power forecasting errors and a mathematic expectation of the power shortage caused by forecasting errors are established.Then,the total mathematic expectation of power shortage from all WFs is minimized.Case study with respect to power dispatch in a WF cluster is conducted using forecasting and actual wind power data within 30 days from sites located at Gansu Province.Compared with the variable proportion method,the power shortage of the WF cluster caused by wind power forecasting errors is reduced.Along with the increment of wind power integrated into power systems,the method positively influences future wind power operation. | Ning CHEN Qi WANG Liangzhong YAO Lingzhi ZHU Yi TANG Fubao WU Mei CHEN Ningbo WANG | 2013 | Journal of Modern Power Systems and Clean Energy2013，1，1： | 3 |
| 6 | Temperature dependent spectral response characteristic of Ⅲ-Ⅴ compound tandem cell显示文摘The GaInP/GaAs/Ge triple-junction tandem cells with a conversion efficiency of 27.1% were fabricated using metalorganic chemical vapor deposition (MOCVD) technique. Temperature dependence of the spectral response measurements of the GaInP/GaAs/Ge tandem cell was performed by a quantum effi- ciency system at temperatures ranging from 25℃ to 160℃. The red-shift phenomena of the absorption limit for all subcells were observed with increasing temperature, which is dued to the energy gap nar-rowing with temperature. The short-circuit current densities (Jsc) of GaInP, GaAs and Ge subcells at room temperature calculated based on the spectral response data were 12.9, 13.7 and 17 mA/cm2, re- spectively. The temperature coefficient of Jsc for the tandem cell was determined to be 8.9 μA/(cm2·℃), and the corresponding temperature coefficient of the open-circuit voltage deduced from the se- ries-connected model was -6.27 mV/℃. | LIU Lei CHEN NuoFu WANG Yu BAI YiMing CUI Min GAO FuBao | 2009 | Chinese Science Bulletin2009，54，3： | 2 |
| 7 | Quantum efficiency and temperature coefficients of GaInP/GaAs dual-junction solar cell显示文摘GaInP/GaAs dual-junction solar cell with a conversion efficiency of 25.2% has been fabricated using metalorganic chemical vapor deposition(MOCVD) technique.Quantum efficiencies of the solar cell were measured within a temperature range from 25 to 160 ℃.The results indicate that the quantum ef-ficiencies of the subcells increase slightly with the increasing temperature.And red-shift phenomena of absorption limit for all subcells are observed by increasing the cell's work temperature,which are consistent with the viewpoint of energy gap narrowing effect.The short-circuit current density tem-perature coefficients dJsc/dT of GaInP subcell and GaAs subcell are determined to be 8.9 and 7.4 μA/cm2/℃ from the quantum efficiency data,respectively.And the open-circuit cell voltage temperature coefficients dVoc/dT calculated based on a theoretical equation are-2.4 mV/℃ and-2.1 mV/℃ for GaInP subcell and GaAs subcell. | LIU Lei CHEN NuoFu BAI YiMing CUI Ming ZHANG Han GAO FuBao YIN ZhiGang ZHANG XingWang | 2009 | Science China(Technological Sciences)2009，52，5： | 2 |
| 8 | Effect of Y_2O_3-MgO Addition on Heterogeneous Precipitation-Thermal Reduction Synthesis and Sintering of FeeMo/Si_3N_4 Powders显示文摘Effect of Y2O3e-MgO addition on heterogeneous precipitation-thermal reduction synthesis and the sintering of Fee Mo/Si3N4 powders has been investigated. It was found that the whiskers-like b-Si3N4, good wettability phases on Si3N4 surface, and high toughness Fe phase appeared in Fee Mo/Si3N4 cermets with Y2O3-MgO additives. The results show that Y2O3-MgO additives can effectively optimize the microstructures of Fee Mo/Si3N4 cermets, and improve the material mechanical properties. Therefore, it indicated that Y2O3-MgO additives can be used for strengthening of sintered cermets, and the dual function of whiskers self-toughening and different metal-composition toughening can be achieved in Fee Mo/Si3N4 cermets with Y2O3-MgO additives. | Ruiming Yin Fubao Ji Qinglin Hou Fusheng Liu Jing Li Linzhang Chen | 2014 | Journal of Materials Science & Technology2014，30，3： | 2 |
| 9 | Organosolv pretreatment by crude glycerol from oleochemicals industry for enzymatic hy?drolysis of wheat straw显示文摘 | Sun Fubao Chen Hongzhang | 2008 | Bioresource Technology2008，99，13： | 1 |
| 10 | Evaluation of enzymatic hydrolysis wheat straw pretreated by atmospheric glycerol autocatalysis显示文摘 | Sun Fubao Chen Hongzhang | 2007 | J Chem Tech Biotech2007，82，： | 1 |
| 11 | Enhanced enzymatic hydrolysis of wheat straw by aqueous glycerol pretreatment显示文摘 | Sun Fubao Chen Hongzhang | 2008 | Bioresource Technology2008，99，： | 1 |
| 12 | Optimization of air quantity regulation in mine ventilation networks using the improved differential evolution algorithm and critical path method显示文摘 | Chen Kaiyan Si Junhong Zhou Fubao Zhang Renwei Cheng Jianwei Shao He Zhao Hongmei | 2014 | International Journal of Mining Science and Technology2014，，： | 1 |
| 13 | Enhanced enzymatic hydrolysis of wheat straw by aqueous glycerol pretreatment显示文摘 | Fubao Sun Hongzhang Chen | 2008 | Bioresource Technology2008，99，14： | 1 |
| 14 | Enhanced enzymatic hydrolysis of wheat straw by aqueous glycerol pretreatment显示文摘 | Sun Fubao Chen Hongzhang | 2008 | Bioresource Technology2008，99，14： | 1 |
| 15 | Comparison of atmospheric aqueous glycerol and steam explosion pretreatments of wheat straw for enhanced enzymatic hydrolysis显示文摘 | Sun Fubao Chen Hongzhang | 2008 | J Chem Technol Biotechnol2008，83，5： | 1 |
| 16 | Evaluation of enzymatic hydroly?sis of wheat straw pretreated by atmospheric glycerol autocataly?sis显示文摘 | Sun Fubao Chen Hongzhang | 2007 | Journal of Chemical Technology & Biotechnology2007，82，11： | 1 |
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