|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Reversing drug resistance of soft tumor-repopulating cells by tumor cell-derived chemotherapeutic microparticles显示文摘颠倒使人重新住入肿瘤的房间(TRC ) 的药抵抗或起源的发展中的新奇途径像房间的癌症房间是迫切临床的需要改进癌症病人的结果。这里,我们显示出用肿瘤颠倒 TRC 的药抵抗的一条创新途径包含反肿瘤药的导出房间的 microparticles (T-MPs ) 。由比区分的癌症房间更可变形的优点, TRC 优先地收起 T-MPs 在进入房间以后释放反肿瘤药,它接着导致 TRC 的死亡。内在的机制包括防碍药流出并且支持这些药的原子入口。我们的调查结果在用有希望的临床的应用程序颠倒 TRC 的药抵抗在 T-MPs 的举起和一条新奇途径的有效性表明肿瘤房间柔软的重要性。 | Jingwei Ma Yi Zhang Ke Tang Huafeng Zhang Xiaonan Yin Yong Li Pingwei Xu Yanling Sun Ruihua Ma Tiantian Ji Junwei Chen Shuang Zhang Tianzhen Zhang Shunqun Luo Yang Jin Xiuli Luo Chengyin Li Hongwei Gong Zhixiong Long Jinzhi Lu Zhuowei Hu Xuetao Cao Ning Wang Xiangliang Yang Bo Huang | 2016 | Cell Research2016，26，6： | 17 |
| 2 | Stable isotope fractionation of chlorine during evaporation of brine from a saline lake显示文摘Brine from the saline Qarhan Lake was evaporated at 28±2°C in a clean environment.Two groups of experiments were conducted;one with complete separation of precipitate and brine at different stages of evaporation,and the other with continuous precipitation during the evaporation.Seventy-nine precipitate and brine samples were collected during the experiments,and the δ37 Cl values were determined using an improved thermal ionization mass spectrometry procedure for precise measurement of chlorine isotopes based on Cs2Cl+ ions.Based on the concentrations of Na+,K+,and Mg2+,evaporation was divided into three main precipitation stages as follows:halite dominant,carnallite dominant,and bischofite dominant.The δ37 Clsolid and δ37 Clliquid values of the precipitate and coexisting brine samples at different stages showed the following characteristics.The precipitates were enriched with 37 Cl relative to the coexisting brine samples,and the δ37 Cl of both the precipitate and brine samples decreased gradually during evaporation.The fractionation factors(αh) between halite and brine were the highest,followed by that(αc) between carnallite and brine,and then that(αb) between bischofite and brine.The αc and αb values of less than one,which indicate the precipitate is enriched in 35 Cl,were found when the evaporation process entered a new stage.However,the δ37 Cl values of carnallite,bischofite,and the coexisting brine samples decreased during evaporation.The residual brine is a 35 Cl reservoir.The experimental phenomena were consistent with the δ37 Cl values in saline deposits in the literature.δ37 Cl can be used as an indicator of brine evaporation processes,which is important in the exploration of sylvinite deposits. | LUO ChongGuang XIAO YingKai MA HaiZhou MA YunQi ZHANG YanLing HE MaoYong | 2012 | Chinese Science Bulletin2012，57，15： | 6 |
| 3 | An antiretroviral regimen containing 6 months of stavudine followed by long-term zidovudine for first-fine HIV therapy is optimal in resource-limited settings: a prospective, multicenter study in China显示文摘 | Li Taisheng Guo Fuping Li Yijia Zhang Chengda Han Yang Lye Wei He Yun Lu Hongzhou Xie Jing Huang Aiqiong Li Yanling Tang Xiaoping Wang Hui Zhang Tong Gao Guiju Lei Junkang Zhang Xiaoying Wu Xinhua Sun Yongtao Bai Jinsong Luo Ling Wang Huanlmg | 2014 | Chinese Medical Journal2014，，1： | 6 |
| 4 | Comparison of Olanzapine versus Other Second-Generation Antipsychotics in the Improvement of Insight and Medication Discontinuation Rate in Schizophrenia显示文摘 | Hongbo HE Yanling ZHOU Mingzhe YANG Xiongxiong LI Yu-Tao XIANG Jiandong LUO | 2018 | 上海精神医学2018，30，3： | 3 |
| 5 | Rapid isolation and immune profiling of SARS-CoV-2 specific memory B cell in convalescent COVID-19 patients via LIBRA-seq显示文摘B cell response plays a critical role against SARS-CoV-2 infection.However,little is known about the diversity and frequency of the paired SARS-CoV-2 antigen-specific BCR repertoire after SARS-CoV-2 infection.Here,we performed single-cell RNA sequencing and VDJ sequencing using the memory and plasma B cells isolated from five convalescent COVID-19 patients,and analyzed the spectrum and transcriptional heterogeneity of antibody immune responses.Via linking BCR to antigen specificity through sequencing(LIBRA-seq),we identified a distinct activated memory B cell subgroup(CD11c^(high) CD95^(high))had a higher proportion of SARS-CoV-2 antigen-labeled cells compared with memory B cells.Our results revealed the diversity of paired BCR repertoire and the non-stochastic pairing of SARS-CoV-2 antigen-specific immunoglobulin heavy and light chains after SARS-CoV-2 infection.The public antibody clonotypes were shared by distinct convalescent individuals.Moreover,several antibodies isolated by LIBRA-seq showed high binding affinity against SARS-CoV-2 receptor-binding domain(RBD)or nucleoprotein(NP)via ELISA assay.Two RBD-reactive antibodies C14646P3S and C2767P3S isolated by LIBRA-seq exhibited high neutralizing activities against both pseudotyped and authentic SARS-CoV-2 viruses in vitro.Our study provides fundamental insights into B cell response following SARS-CoV-2 infection at the single-cell level. | Bing He Shuning Liu Yuanyuan Wang Mengxin Xu Wei Cai Jia Liu Wendi Bai Shupei Ye Yong Ma Hengrui Hu Huicui Meng Tao Sun Yanling Li Huanle Luo Mang Shi Xiangjun Du Wenjing Zhao Shoudeng Chen Jingyi Yang Haipeng Zhu Yusheng Jie Yuedong Yang Deyin Guo Qiao Wang Yuwen Liu Huimin Yan Manli Wang Yao-Qing Chen | 2021 | Signal Transduction and Targeted Therapy2021，6，6： | 2 |
| 6 | Sample preparation for isotopic determination of boron in clay sediments显示文摘The procedures of sample preparation for isotopic determination of boron in clay sediments is very cumbersome, by far, there haven't been relevant reports on that. In order to establish an effective method for sample preparation, a series of experiments were carried out. In this paper, boron in clay sediments was extracted with HCl solution and purified by two-step ion exchange method. Extracted HCl solution should be adjusted to alkalescency before passing through the Amberlite IRA 743 resin column due to the fact that Amberlite IRA 743 resin absorbs boron only from alkalescent solution. However, a mass of hydroxides of Al and Fe will be precipitated when the extracted HCl solution becomes alkalescent. Hydroxides of Al and Fe have a strong adsorption capacity for boron, which can cause boron isotope fractionation. To treat precipitated hydroxides of Al and Fe, four procedures, namely direct ion exchange (DRIE), decationizing ion exchange (DCIE), once sedimentation ion exchange (OSIE) and repeated sedimentation ion exchange (RSIE) were used and assessed. The influences of the four procedures on separation and extraction and isotopic composition of boron in experimental solutions and clay sediments were also discussed. According to the results, the DRIE, DCIE and OSIE are improper. The result of sample determination indicates that when extracting boron via RSIE, with the increase of precipitation times, there's an obvious decrease in boron content in the precipitated hydroxides while a sharp increase in recovery of boron and it is favorable for weakening the influence of boron isotope fractionation. But the process of RSIE is time consuming and it may introduce boron. It needs further research to establish a more effective sample preparation method for isotopic deter- mination of boron in clay sediments. | ZHANG Yanling XIAO Yingkai MA Yunqi ZHUGE Qin LIU Zhiqi HE Maoyong LUO Chongguang MA Haizhou | 2013 | Chinese Journal Of Geochemistry2013，32，2： | 2 |
| 7 | A novel route to prepare Fe3 04/P(MAA-'o-NVP) cross-linked magnetic composite micro- spheres with core-shell architecture by surface-initiated radical dispersion polymerization显示文摘 | Di Hongwei Luo Yanling Xu Peng | 2010 | Journal of Nanoscience and Nano- technology2010，10，12： | 1 |
| 8 | Clinical application of traditional herbal medicine in five countries and regions: Japan;South Korea;China's Mainland;Hong Kong, China;Taiwan, China显示文摘Objective:To study the characteristics of the clinical application of traditional herbal medicine in five countries and regions where traditional medicine(TM)is widely used:Japan;South Korea;China's Mainland;Hong Kong,China;Taiwan,China.And to analyze,from multiple angles,the variations in the methods of TM used in each countries and regions.Methods:Fifty commonly used traditional herbs(TOP50)from classical formulae were selected,and descriptive statistics,correlation analyses,and Friedman test were used to compare methods of clinical application and dosages in the countries and regions of interest based on a retrospective review of randomly-selected medical records.Results:There were significant differences in sequencing TOP50 among the five countries and regions(P<.01).The adherence to the classical formulae,from strong to weak was Japan;China's Mainland;Taiwan,China;Hong Kong,China;South Korea.There were also significant differences in TOP50 dosing regimens(P<.01).Overall dosages of TOP50 from high to low were:China's Mainland;Hong Kong,China;Taiwan,China;South Korea;Japan.Finally,there were significant differences in the dosage intervals(P<.01),with dosage intervals from maximum to minimum as follows:China's Mainland;Taiwan,China;Hong Kong,China;South Korea;Japan.Conclusions:The clinical dosages of traditional herbal medicine used in the China's Mainland are relatively large compared with those prescribed in the other four countries and regions,and the range of dosages in China's Mainland is more flexible.On the other hand,clinical dosages of TOP50 are the lowest in Japan,where the dosage range is also the narrowest,supporting the idea that Doctors of Kampo medicine are highly cautious and are likely to adhere strictly to classical formulae,while Hong Kong,China and Taiwan,China are in the middle.The dosage of TOP50 in South Korea is significantly lower than that used in the China's Mainland;Hong Kong,China and Taiwan,China where the adherence to the classical formulae was the lowest,albeit slightly higher than that in Japan.The methods of clinical application of traditional herbal medicine in the five countries and regions were affected by multiple factors,including history,geography,climate,and culture. | Liming Chen Yanling Fu Lin Zhang Sijia Zhao Qing Feng Yihua Cheng Tosha Yanai Daji Xu Mingyu Luo Sang Woo An Woong Seok Lee Seong Hoon Cho Byung Wook Lee | 2015 | Journal of Traditional Chinese Medical Sciences2015，2，3： | 1 |
| 9 | Synthesis, characterization, and swelling kinetics of pH-responsive and temperature-responsive carboxymethyl chitosan/ polyacrylamide hydrogels 显示文摘 | Wei Qingbo Luo Yanling Fu Feng | 2012 | Journal of Applied Polymer Science2012，129，2： | 1 |
| 10 | HIV epidemic in Yunnan 1989-2007 显示文摘 | Manhong Jia Hongbing Luo Yanling Ma | 2010 | Aequir Immune Defic Syndr2010，53，1： | 1 |
| 11 | Enhancement ofp-Nucleated Crytallization in Polypropylene Random Copoly-mer via Adding Isotactic Polypropylene 显示文摘 | Luo Feng Zhu Yanling Wang Ke | 2012 | Polymer2012，53，21： | 1 |
| 12 | Synthesis and characterization of a pH- and ionic strength-responsive hy- dregel 显示文摘 | Zhang Kaipu Luo Yanling Li Zhanging | 2007 | Soft Mater2007，5，4： | 1 |
| 13 | P ( AAm-co- MAA) semi-IPN hybrid hydrogels in the presence of PANI and MWNTs-COOH:improved swelling behavior and me- chanical properties 显示文摘 | Liu Zhanqing Luo Yanling Zhang Kaipu | 2008 | J Biomater Sci: Polym Ed2008，19，11： | 1 |
| 14 | Recovery of fertility in quinestrol-treated or diethylstilbestroltreated mice:Implications for rodent management显示文摘Fertility control is an alternative strategy to traditional culling for the management of rodent pests.Previous studies have demonstrated that quinestrol is a potential contraceptive for male rodents,but the recovery of fertility in quinestrol-treated rodents has not been evaluated.This study used C57BL/6J mice to evaluate the recovery rate of male fertility after the administration of quinestrol.Diethylstilbestrol(DES),a non-steroid estrogenic compound,was used for comparison.Different groups of mice were treated with 1 mg/kg quinestrol,1 mg/kg DES,or castor oil separately for 7 days.These mice were then killed on days 8,22 and 50 respectively.Our results indicated that the weight of epididymides and seminal vesicles decreased significantly on days 8 and 22 in quinestrol/DES-treated mice,with extensive histological changes in the seminiferous tubules.Sperm concentrations in the cauda epididymal fluid were significantly reduced on days 8 and 22 in both quinestrol and DES treatment groups and on day 50 for the DES,but not the quinestrol group.Further analysis revealed that DES-treated mice exhibited a higher proportion of abnormal sperm accumulation in the epididymis,indicating that the normal sperm transportation to the cauda epididymis was blocked.Our results indicate that the anti-fertility effects on male mice given quinestrol were of shorter duration than for those receiving DES at the dose of 1 mg/kg body weight. | Ming LIU Rongcan LUO Hao WANG Guangming CAO Yanling WANG | 2017 | Integrative Zoology2017，12，3： | 1 |
| 15 | Preparation, fabrication and response behavior of a HTBN/TDI/MWNT composite sensing film by in situ dispersed polymerization显示文摘 | Luo Yanling Wang Chao Li Zhanqin | 2007 | Synthetic Metals2007，157，： | 1 |
| 16 | Method for measuring the steering wheel angle of paddy field agricultural machinery by integrating RTK-GNSS and dual-MEMS gyroscope显示文摘Aiming at the application environment of paddy agricultural machinery with bumpy and undulating changes,the problems affecting the method for steering wheel angle measurement by MEMS gyroscope were analyzed,and a wheel angle measurement method combining Dual-MEMS gyroscope(dual MEMS gyroscope)and RTK-GNSS was designed.The adaptive weighting method was used to fuse the heading angle differentiation of RTK-GNSS,the MEMS gyroscope angle rate,and velocity data,and the rod-arm compensation was performed to accurately obtain the angle rates of the body and steering wheels of agricultural machinery;the difference between the combined angular rate of the steering wheel of the agricultural machinery and the angular rate of the agricultural machinery body was obtained,and the integrator is used to integrate the difference to get the wheel steering angle value,and the Kalman filter was designed to make feedback correction for the integration process of angle calculation to eliminate the errors caused by the gyroscope zero bias,random drift,and gyroscope rod arm effect,and to obtain the accurate value of wheel steering angle.A comparative test with the connecting rod wheel angle sensor was designed,and the results show that the maximum deviation is 4.99°,the average absolute average value is 1.61°,and the average standard deviation is 0.98°.The method in this study and the connecting rod wheel angle sensor were used on paddy farm machinery.The wheel angle measurement deviation of the proposed method and the connecting rod wheel angle sensor was not more than 1°,which is relatively small.It has good stability,speed adaptability,and dynamic responsiveness that meets the accuracy requirements of steering wheel angle measurement for paddy field agricultural machinery unmanned driving and can be used instead of connecting rod angle sensors for unmanned agricultural machinery. | Pei Wang Lian Hu Jie He Siqi Ke Zhongxian Man Tuanpeng Tu Luning Yang Yuanyuan Li Yanling Yi Weicong Li Xiwen Luo | 2022 | International Journal of Agricultural and Biological Engineering2022，15，6： | 1 |
| 17 | Novel THTBN/MWNTs-OHpolyurethane conducting composite thin films for applications indetection of volatile organic compounds显示文摘 | Xu Feng Guo Shuang Luo Yanling | 2014 | Materials Chemistry &Physics2014，145，22： | 1 |
| 18 | The impact of sulfate reduction on the distribution of methylmercury in reservoirs in the city of Guiyang显示文摘In this paper, the relationship between sulfate reduction potential and mercury methylation potential was studied in the Aha, Baihua and Hongfeng reservoirs from Guiyang City. The methylmercury (MeHg) concentrations of lake water in the Aha Reservoir were greatly elevated as compared to those of the Hongfeng and Baihua reservoirs, which was correlated with its distinctly high SRB abundance, SO42-, and S2- concentrations. Among the three reservoirs, however, the highest MeHg was observed in in the top several centimenters of pore water profile in the Hongfeng Reservoir where the lowest S2- in pore water occurred. The distributions of MeHg in lake water and pore water showed the highest methylation potential occurred at water-sediment surface for the Aha Reservoir and the in the top several centimenters of sediments for the Hongfeng Reservoir. It is guessed that the highest mercury methylation only occurs at the sites with certain sulfide concentrations. | HE Tianrong LI Ting Yang Ruidong LUO Guangjun LANG Xiaofang An Yanling YAN Haiyu | 2013 | Chinese Journal Of Geochemistry2013，32，1： | 1 |
| 19 | Synthesis and characterizationof novel h-HTBN/PEG PU copolymers:Effect ofsurface properties on hemocompatibility显示文摘 | Nan YunFei Luo YanLing Xu Feng | 2011 | Polymers for AdvancedTechnologies2011，22，80： | 1 |
| 20 | Electrothermal Performances of Poly(Vinylidiene Fluoride)/Fluorine Rubber Conductive Composite Filled with Carbon Black显示文摘The conductive polymer composites and their corresponding resistors with PTC (positive temperature coefficient) characteristic can be manufactured by mixing conductive carbon blacks with poly(vinylidiene fluoride )matrix. The Joule heat can produce when alternative voltage is exerted on the composite resistors, and the resistors can produce when alternative voltage is exerted on the current from flowing at a high temperature because of their PTC effect, thus becoming a kind of important thermoelectric switching materials as heating, temperature-controlling and currentlinfiting element applications. | LUO YanLing | 2001 | Chemical Research in Chinese Universities2001，17，z1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员