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| 1 | Accuracy and spatio-temporal variation of high resolution satellite rainfall estimate over the Ganjiang River Basin显示文摘Based on spatial interpolation rainfall of the ground gauge measurement,we proposed a method to comprehensively evaluate and compare the accuracy of satellite rainfall estimates (SREs) at three spatial scales:0.25°×0.25° grid scale,sub-catchment scale and the whole basin scale.Using this method,we evaluated the accuracy of six high-resolution monthly SREs (TRMM 3B42 V6,3B42RT V6,CMORPH,GSMaP MWR+,GSMaP MVK+ and PERSIANN) and revealed the spatio-temporal variation of the SRE accuracy based on spatial interpolated rainfall from a dense network of 325 gauges during 2003-2009 over the Ganjiang River Basin in the Southeast China.The results showed that ground gauge-calibrated 3B42 had the highest accuracy with slight overestimation,whereas the other five uncalibrated SREs had severe underestimation.The accuracy of the six SREs in wet seasons was remarkably higher than that in the dry seasons.When the time scale was expanded,the accuracy of SRE,particularly 3B42,increased.Furthermore,the accuracy of SREs was relatively low in the western mountains and northern piedmont areas,while it was relatively high in the central and southeastern hills and basins of the Ganjiang River Basin.When the space scale was expanded,the accuracy of the six SREs gradually increased.This study provided an example for of SRE accuracy validation in other regions,and a direct basis for further study of SRE-based hydrological process. | HU QingFang YANG DaWen WANG YinTang YANG HanBo | 2013 | Science China(Technological Sciences)2013，56，4： | 19 |
| 2 | KAI1/CD82 suppresses hepatocyte growth factorinduced migration of hepatoma cells via upregulationof Sprouty2显示文摘We conducted a study concerning the suppressive mechanism of KAI1/CD82 on hepatoma cell metastasis.Hepatocyte growth factor(HGF)induces the migration of hepatoma cells through activation of cellular sphingosine kinase 1(SphK1).Adenovirus-mediated gene transfer of KAI1(Ad-KAI1)downregulates the SphK1 expression and suppresses the HGF-induced migration of SMMC-7721 human hepatocellcular carcinoma cells.Overexpression of KAI1/CD82 significantly elevates Sprouty2 at the protein level.Ablation of Sprouty2 with RNA interference can block the KAI1/CD82-induced suppression of hepatoma cell migration and downregulation of SphK1 expression.It is demonstrated that KAI1/CD82 suppresses HGF-induced migration of hepatoma cells via upregulation of Sprouty2. | MU ZhenBin1 ,3,WANG Hua 2,ZHANG Jing 2,LI QingFang 2,WANG LiSheng 2&GUO XiaoZhong 3 1State Key Laboratory of Cancer Biology and Institute of Digestive Diseases,Xijing Hospital,Fourth Military Medical University,Xi’an 710032,China 2Department of Experimental Hematology,Beijing Institute of Radiation Medicine,Beijing 100850,China 3Department of Gastroenterology,Shenyang General Hospital of PLA,Shenyang 110016,China | 2008 | Science China(Life Sciences)2008，51，7： | 7 |
| 3 | Whole-genome sequencing provides insights into the genetic diversity and domestication of bitter gourd(Momordica spp.)显示文摘Bitter gourd(Momordica charantia)is a popular cultivated vegetable in Asian and African countries.To reveal the characteristics of the genomic structure,evolutionary trajectory,and genetic basis underlying the domestication of bitter gourd,we performed whole-genome sequencing of the cultivar Dali-11 and the wild small-fruited line TR and resequencing of 187 bitter gourd germplasms from 16 countries.The major gene clusters(Bi clusters)for the biosynthesis of cucurbitane triterpenoids,which confer a bitter taste,are highly conserved in cucumber,melon,and watermelon.Comparative analysis among cucurbit genomes revealed that the Bi cluster involved in cucurbitane triterpenoid biosynthesis is absent in bitter gourd.Phylogenetic analysis revealed that the TR group,including 21 bitter gourd germplasms,may belong to a new species or subspecies independent from M.charantia.Furthermore,we found that the remaining 166 M.charantia germplasms are geographically differentiated,and we identified 710,412,and 290 candidate domestication genes in the South Asia,Southeast Asia,and China populations,respectively.This study provides new insights into bitter gourd genetic diversity and domestication and will facilitate the future genomics-enabled improvement of bitter gourd. | Junjie Cui Yan Yang Shaobo Luo Le Wang Rukui Huang Qingfang Wen Xiaoxia Han Nansheng Miao Jiaowen Cheng Ziji Liu Changyuan Zhang Chengcheng Feng Haisheng Zhu Jianwen Su Xinjian Wan Fang Hu Yu Niu Xiaoming Zheng Yulan Yang Dai Shan Zhensheng Dong Weiming He Narinder P.S.Dhillon Kailin Hu | 2020 | Horticulture Research2020，7，1： | 7 |
| 4 | The heterogeneity of islet autoantibodies and the progression of islet failure in type 1 diabetic patients显示文摘Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This study was to investigate prevalence and heterogeneity of the islet autoantibodies and clinical phenotypes of type 1 diabetes mellitus; and also discussed the process of islet failure and its risk factors in Chinese type 1 diabetic patients. A total of 1,291 type 1 diabetic patients were enrolled in this study. Demographic information was collected. Laboratory tests including mixed-meal tolerance test, human leukocyte antigen alleles, hemoglobin A1 c, lipids, thyroid function and islet autoantibodies were conducted. The frequency of islet-specific autoantibody in newly diagnosed T1 DM patients(duration shorter than half year) was 73% in East China. According to binary logistic regressions, autoantibody positivity, longer duration and lower Body Mass Index were the risk factors of islet failure. As the disease developed, autoantibodies against glutamic acid decarboxylase declined as well as the other two autoantibodies against zinc transporter 8 and islet antigen 2. The decrease of autoantibodies was positively correlated with aggressive beta cell destruction. Autoantibodies can facilitate the identification of classic T1 DM from other subtypes and predict the progression of islet failure. As there were obvious heterogeneity in autoantibodies and clinical manifestation in different phenotypes of the disease, we should take more factors into consideration when identifying type 1 diabetes mellitus. | Jin Liu Lingling Bian Li Ji Yang Chen Heng Chen Yong Gu Bingqin Ma Wei Gu Xinyu Xu Yun Shi Jian Wang Dalong Zhu Zilin Sun Jianhua Ma Hui Jin Xing Shi Heng Miao Bing Xin Yan Zhu Zhenwen Zhang Ruifang Bu Lan Xu Guangde Shi Wei Tang Wei Li Dongmei Zhou Jun Liang Xingbo Cheng Bimin Shi Jixiang Dong Ji Hu Chen Fang Shao Zhong Weinan Yu Weiping Lu Chenguang Wu Li Qian Jiancheng Yu Jialin Gao Xiaoqiang Fei Qingqing Zhang Xueqin Wang Shiwei Cui Jinluo Cheng Ning Xu Guofeng Wang Guoqing Han Chunrong Xu Yun Xie Minmin An Wei Zhang Zhixiao Wang Yun Cai Qi Fu Yu Fu Shuai Zheng Fan Yang Qingfang Hu Hao Dai Yu Jin Zheng Zhang Kuanfeng Xu Yifan Li Jie Shen Hongwen Zhou Wei He Xuqin Zheng Xiao Han Liping Yu Jinxiong She Mei Zhang Tao Yang | 2016 | Science China(Life Sciences)2016，59，9： | 5 |
| 5 | Crystalline behaviors and phase transition during the manufacture of fine denier PA6 fibers显示文摘Recently we have successfully produced fine denier PA6 fibers by using additives containing lanthanide compounds.Meanwhile,crystallization and phase transition of PA6 fibers during spinning and drawing processes were investigated.During the spinning process,β phase crystal could be obtained in as-spun PA6 fibers which were produced with relatively high melt draw ratio,while γ phase crystal predominated when the melt draw ratio was relatively low.β phase crystal,whose behaviors are similar with those of γ phase by FT-IR and XRD characterization,could be transformed to α form easily when PA6 fibers are immersed in boiling water.However,γ phase crystal of PA6 remains unchanged in boiling water.Thus,β and γ phase crystals of PA6 can be differentiated by the crystalline behaviors of PA6 fibers after treatment in boiling water.Further experiments demonstrate that the β phase can also be produced during a drawing process where a phase transformation from γ to α occurs.In other words,β phase may act as an intermediate state during the phase transformation. | ZHANG ChengFeng LIU YuHai LIU ShaoXuan LI HuiZhen HUANG Kun PAN QingHua HUA XiaoHui HAO ChaoWei MA QingFang LV ChangYou LI WeiHong YANG ZhanLan ZHAO Ying WANG DuJin LAI GuoQiao JIANG JianXiong XU YiZhuang WU JinGuang | 2009 | Science China Chemistry2009，52，11： | 4 |
| 6 | Efficient CO_2 capture on low-cost silica gel modified by polyethyleneimine显示文摘In this work,a series of polyethyleneimine(PEI) functionalized commercial silica gel were prepared by wet impregnation method and used as CO 2 sorbent.The as-prepared sorbents were characterized by N 2 adsorption,FT-IR and SEM techniques.CO 2 capture was tested in a fixed bed reactor using a simulated flue gas containing 15.1% CO 2 in a temperature range of 25-100 C.The effects of sorption temperature and amine content on CO 2 uptake of the adsorbents were investigated.The silica gel with a 30 wt% PEI loading manifested the largest CO 2 uptake of 93.4 mg CO 2 /g adsorbent(equal to 311.3 mg CO 2 /g PEI) among the tested sorbents under the conditions of 15.1%(v/v) CO 2 in N 2 at 75 C and atmospheric pressure.Moreover,it was rather low-cost.In addition,the PEI-impregnated silica gel exhibited stable adsorption-desorption behavior during 5 consecutive test cycles.These results suggest that the PEI-impregnated silica gel is a promising and cost-effective sorbent for CO 2 capture from flue gas and other stationary sources with low CO 2 concentration. | Ke Wang Hongyan Shang Lin Li Xinlong Yan Zifeng Yan Chenguang Liu Qingfang Zha | 2012 | Journal of Natural Gas Chemistry2012，21，3： | 4 |
| 7 | Goal directed fluid therapy with LiDCOrapid in a parturient with WPW syndrome and cardiac dysfunction undergoing emergent cesarean section显示文摘 | Xiao Wei Duan Qingfang Zhao Lei Wang Fengying Wang Tianlong | 2014 | Chinese Medical Journal2014，，14： | 3 |
| 8 | Study on Thermal Insulation Performance of Cross-Laminated Bamboo Wall显示文摘In recent years,bamboo,as a green building material,has attracted more and more attention worldwide.Inspired by the investigation of cross-laminated timber in structural systems,a new engineered cross-laminated bamboo(CLB)consisting of the cross lamination of bamboo scrimber plates is proposed in this paper.To evaluate its potential in structural applications,the thermal insulation performances of the CLB walls and CLB walls with the EPS foam plate were studied and evaluated by the temperature-controlled box-heat flow meter method.Test results indicated that the thermal insulation performance improved with the increase of thickness,but different wall configurations had little effect on the thermal insulation performance under the same thickness of the CLB wall.The thermal insulation performance of EPS-CLB composite wall was much better than that of CLB wall.In addition,a relatively acceptable accuracy of the theoretical calculations was proved.Finally,the influence of different locations of the EPS foam plate on heat transfer coefficient can be neglected as it was studied based on the validated numerical models. | Qingfang Lv Weiyang Wang Ye Liu | 2019 | Journal of Renewable Materials2019，7，11： | 3 |
| 9 | Effects of rotational tillage practices on soil properties, winter wheat yields and water-use efficiency in semi-arid areas of north-west China显示文摘 | Xianqing Hou Rong Li Zhikuan Jia Qingfang Han Wei Wang Baoping Yang | 2012 | Field Crops Research2012，，： | 2 |
| 10 | Applications of nanogenerators for biomedical engineering and healthcare systems显示文摘The dream of human beings for long living has stimulated the rapid development of biomedical and healthcare equipment.However,conventional biomedical and healthcare devices have shortcomings such as short service life,large equipment size,and high potential safety hazards.Indeed,the power supply for conventional implantable device remains predominantly batteries.The emerging nanogenerators,which harvest micro/nanomechanical energy and thermal energy from human beings and convert into electrical energy,provide an ideal solution for self-powering of biomedical devices.The combination of nanogenerators and biomedicine has been accelerating the development of self-powered biomedical equipment.This article first introduces the operating principle of nanogenerators and then reviews the progress of nanogenerators in biomedical applications,including power supply,smart sensing,and effective treatment.Besides,the microbial disinfection and biodegradation performances of nanogenerators have been updated.Next,the protection devices have been discussed such as face mask with air filtering function together with real-time monitoring of human health from the respiration and heat emission.Besides,the nanogenerator devices have been categorized by the types of mechanical energy from human beings,such as the body movement,tissue and organ activities,energy from chemical reactions,and gravitational potential energy.Eventually,the challenges and future opportunities in the applications of nanogenerators are delivered in the conclusive remarks. | Wanli Wang Jinbo Pang Jie Su Fujiang Li Qiang Li Xiaoxiong Wang Jingang Wang Bergoi Ibarlucea Xiaoyan Liu Yufen Li Weijia Zhou Kai Wang Qingfang Han Lei Liu Ruohan Zang Mark HRümmeli Yang Li Hong Liu Han Hu Gianaurelio Cuniberti | 2022 | InfoMat2022，4，2： | 2 |
| 11 | Amultimedia fate model to evaluate the fate of PAHs inSonghua River,China 显示文摘 | WANG Ce FENG Yujie SUN Qingfang | 2012 | Environmental Pollution2012，164，： | 1 |
| 12 | An unusual COVID-19 case with over four months of viral shedding in the presence of low neutralizing antibodies: a case report显示文摘The ongoing coronavirus disease 2019(COVID-19)pandemic is a global public health crisis,causing social and economic disasters in many countries.In China,two-consecutive negative results of nucleic acid tests for SARS-CoV-2 from the respiratory samples are required to end the quarantine of COVID-19 patients.However,clinicians face a dilemma in case of patients with long-term viral shedding.This report described an unusual COVID-19 case who had persistent viral RNA positivity for more than 4 months after initial illness in the presence of low neutralizing antibodies,but without prolonged clinical symptoms.Multiple anti-viral drug treatments had no impact and there was no evidence of re-infection.When the patient was self-quarantined at home,no infection occurred to the three family members living with her for 15 to 19 days.Sputum viral culture in BSL-3 laboratory on the 102nd day after symptom onset was negative.From the 129th day on,8 continuous nucleic acid tests of sputum samples showed negative results.The patient was discharged on 137th days since symptom onset.In conclusion,viral RNA shedding in the sputum of the COVID-19 patient may last over 4 months.As no evidence shows the existence of infectious virus,two-consecutive negative nucleic acid tests may not be the prerequisite for ending quarantine of COVID-19 patients with prolonged viral shedding. | Wei Chen Zhiliang Hu Changhua Yi Yun Chi Qingfang Xiong Chee Wah Tan Yongxiang Yi Lin-Fa Wang | 2020 | The Journal of Biomedical Research2020，34，6： | 1 |
| 13 | A multimedia fate model to evaluate the fate of PAHs in Songhua River,China显示文摘 | Wang Ce Feng Yujie Sun Qingfang | 2012 | Environ Pollut2012，164，： | 1 |
| 14 | Bilateral inferior petrosal sinus sampling for the treatment of Cushing's disease Data from 52 cases from one institute over an eight-year period显示文摘The present study analyzed data from 108 Cushing's disease patients,who underwent trans-sphenoidal surgery in one hospital between January 2003 and April 2010,to investigate the performance value of bilateral inferior petrosal sinus sampling (BIPSS).Of the 108 patients,52 underwent BIPSS prior to surgery and 56 did not.Results showed that BIPSS accuracy for the diagnosis of Cushing's disease was 86.5% (45/52),and accuracy for adenoma lateralization during surgery was 76.9% (40/52).In addition,early remission rate was significantly greater compared to patients without BIPSS.Results demonstrated that BIPSS facilitated localization and diagnosis of Cushing's disease and helped to predict adenoma lateralization. | Changyan Fan Xiuhua Shi Qingfang Sun Liuguan Bian Weiguo Zhao Jiankang Shen Hua Zhang Tingwei Su Weiqing Wang Xiaoying Li Guang Ning Liang Kong Lingling Hu | 2011 | Neural Regeneration Research2011，6，28： | 1 |
| 15 | Spontaneous spinal epidural hematoma: analysis of 23 cases显示文摘 | Zhan Liu Qingfang Jiao Jianguo Xu Xiang Wang Sanzhong Li Chao You | 2008 | Surgical Neurology2008，，： | 1 |
| 16 | Development of a rapid and sensitive LC–MS/MS assay for the determination of combretastatin A4 phosphate, combretastatin A4 and combretastatin A4 glucuronide in beagle dog plasma and its application to a pharmacokinetic study显示文摘 | Xiaojing Wang Zhihang Chen Jinjing Che Qingfang Meng Chengqi Shan Yunan Hou Xiaolei Liu Yifeng Chai Yuanguo Cheng | 2009 | Journal of Chromatography B2009，，30： | 1 |
| 17 | Effects of rotational tillage practices on soil properties, winter wheat yields and water-use efficiency in semi-arid areas of north-west China显示文摘 | Xianqing Hou Rong Li Zhikuan Jia Qingfang Han Wei Wang Baoping Yang | 2012 | Field Crops Research2012，，： | 1 |
| 18 | Aerodynamic effects of impeller-diffuser axial misalignment in low-flow-coefficient centrifugal compressor显示文摘A numerical investigation on the aerodynamic effects of impeller-diffuser axial misalignment in the low-flow-coefficient centrifugal compressor is conducted through three-dimensional CFD analysis.The results show that the flow,especially near the diffuser inlet,is influenced by the axial misalignment obviously.When the impeller offsets to one side,the pressure at diffuser inlet close to this side will descend,and the vortex in the cavity on the other side will partially enter the diffuser and then result in the back flow.The performances of the stage and its components also change with the impeller-diffuser axial misalignment.There exists an optimum offset making the efficiency maximum at a given operating point.Furthermore,the effect of impeller-diffuser axial misalignment on the axial thrust is pronounced.The axial thrust is nearly increased linearly with the increase of axial misalignment.The aerodynamic effects of impeller-diffuser axial misalignment in the low-flow-coefficient centrifugal compressor behaves more remarkably at the large flow rate.To alleviate the aerodynamic effects of impeller-diffuser misalignment,a rounding in the meridional plane at the diffuser inlet can be applied. | WANG ZhiHeng XI Guang LIU QingFang | 2015 | Science China(Technological Sciences)2015，58，1： | 1 |
| 19 | Immigrant underemployment across US metropolitan areas: from a spatial perspective 显示文摘 | WANG Qingfang Tetiana Lysenko | 2014 | Urban Studies2014，51，10： | 1 |
| 20 | Broadband and thin microwave absorber of nickel - zinc ferrite/carbonyl iron composite 显示文摘 | Longgang Yah Jianbo Wang Yunzhe Ye Zhi Hao Qingfang Liu Fashen Li | 2009 | Journal of Alloys and Compounds2009，487，12： | 1 |
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