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| 1 | Magnetic iron oxide nanoparticles accelerate osteogenic differentiation of mesenchymal stem cells via modulation of long noncoding RNA INZEB2显示文摘Nanomaterials 逐渐地为生物医学的应用被使用;因此,理解他们的生物效果是重要的。以前的研究建议磁性的氧化铁 nanoparticles (IONP ) 有修理织物的效果。在现在的学习,我们在间充质的干细胞(MSC ) 探索了 IONP 的细胞的效果并且识别了内在的分子的机制。结果证明我们的同样准备的 IONP 是在 MSC 的在结构上马厩并且支持了 MSC 同样整个的粒子的 osteogenic 区别。而且在分子的水平,我们把 MSC 的基因表示与或没有 IONP 暴露作比较并且长显示出那 IONP upregulated noncoding RNA INZEB2,它为由 MSC 维持成骨不可缺少。而且, INZEB2 downregulated ZEB2 的 overexpression,必要的一个因素镇压 BMP/Smad-dependent osteogenic 抄写。我们也证明在 osteogenic 区别的 INZEB2 的必要角色是 ZEB2 依赖的。在摘要,我们阐明了 MSC 上的 IONP 效果的分子的基础;这些调查结果可以为干细胞的应用用作一个有意义的理论基础到再生药。 | Qiwei Wang Bo Chen Fang Ma Shikang Lin Meng Cao Yan Li Ning Gu | 2017 | Nano Research2017，10，2： | 11 |
| 2 | Near-field magnetic induction communication device for underground wireless communication networks显示文摘Electromagnetic(EM)waves are the most versatile and widely adopted physical layer technology for underground wireless communication networks(UWCNs).However,they are not suitable for underground communication especially when coils are buried in soil.Magneto-inductive(MI)communication is a promising technique for UWCNs;it is not affected by large propagation delays,multipath propagation,and fading.Furthermore,MI communication has lower transmitting power and smaller antenna size than EM.A near-field low-power communication device with an electrically small antenna for low-frequency UWCNs is proposed in this study.The device can be easily buried underground.The proposed device is analyzed in terms of basic communication metrics,i.e.,magnetic field intensity,bandwidth,path losses,and received power.Comparison of these four metrics shows that the experimental data closely match those of the theoretical model,and the maximum communication distance of 28.5 m,can be achieved.Moreover,according to the experimental results of our device,we further propose the modified received power model.Results show that the device exhibits good performance and can be used as a stand-alone module in directional underground wireless communication. | MA Jing ZHANG XiaoTong HUANG QiWei | 2014 | Science China(Information Sciences)2014，57，12： | 7 |
| 3 | Genome-wide identification and expression analyses of cytochrome P450 genes in mulberry(Morus notabilis)显示文摘Cytochrome P450 S play critical roles in the biosynthesis of physiologically important compounds in plants.These compounds often act as defense toxins to prevent herbivory.In the present study,a total of 174 P450 genes of mulberry(Morus notabilis C.K.Schn) were identified based on bioinformatics analyses.These mulberry P450 genes were divided into nine clans and 47 families and were found to be expressed in a tissue-preferential manner.These genes were compared to the P450 genes in Arabidopsis thaliana.Families CYP80,CYP92,CYP728,CYP733,CYP736,and CYP749 were found to exist in mulberry,and they may play important roles in the biosynthesis of mulberry secondary metabolites.Analyses of the functional and metabolic pathways of these genes indicated that mulberry P450 genes may participate in the metabolism of lipids,other secondary metabolites,xenobiotics,amino acids,cofactors,vitamins,terpenoids,and poiyketides.These results provide a foundation for understanding of the structures and biological functions of mulberry P450 genes. | Bi Ma Yiwei Luo Ling Jia Xiwu Qi Qiwei Zeng Zhonghuai Xiang Ningjia He | 2014 | Journal of Integrative Plant Biology2014，56，9： | 5 |
| 4 | Desmoglein 2(DSG2) Is A Receptor of Human Adenovirus Type 55 Causing Adult Severe Community-Acquired Pneumonia显示文摘Human adenovirus type 55(HAdV-B55) is a re-emergent acute respiratory disease pathogen that causes adult communityacquired pneumonia(CAP). Previous studies have shown that the receptor of HAdV-B14, which genome is highly similar with HAdV-B55, is human Desmoglein 2(DSG2). However, whether the receptor of HAdV-B55 is DSG2 is undetermined because there are three amino acid mutations in the fiber gene between HAdV-B14 and HAdV-B55. Here, firstly we found the 3T3 cells, a mouse embryo fibroblast rodent cell line which does not express human DSG2, were able to be infected by HAdV-B55 after transfected with pcDNA3.1-DSG2, while normal 3T3 cells were still unsusceptible to HAdV-B55 infection. Next, A549 cells with h DSG2 knock-down by siRNA were hard to be infected by HAdV-B3/-B14/-B55, while the control siRNA group was still able to be infected by all these types of HAdVs. Finally, immunofluorescence confocal microscopy indicated visually that Cy3-conjugated HAdV-B55 viruses entered A549 cells by binding to DSG2 protein.Therefore, DSG2 is a major receptor of HAdV-B55 causing adult CAP. Our finding is important for better understanding of interactions between adenoviruses and host cells and may shed light on the development of new drugs that can interfere with these processes as well as for the development of potent prophylactic vaccines. | Jing Zhang Kui Ma Xiangyu Wang Yinbo Jiang Shan Zhao Junxian Ou Wendong Lan Wenyi Guan Xiaowei Wu Heping Zheng Bin Yang Chengsong Wan Wei Zhao Jianguo Wu Qiwei Zhang | 2021 | Virologica Sinica2021，36，6： | 4 |
| 5 | Progress of Jinping Underground laboratory for Nuclear Astrophysics(JUNA)显示文摘Jinping Underground laboratory for Nuclear Astrophysics(JUNA) will take the advantage of the ultra-low background of CJPL lab and high current accelerator based on an ECR source and a highly sensitive detector to directly study for the first time a number of crucial reactions occurring at their relevant stellar energies during the evolution of hydrostatic stars. In its first phase, JUNA aims at the direct measurements of^(25)Mg(p,γ)^(26)Al,^(19)F(p,α)^(16)O,^(13)C(α,n)^(16)O and ^(12)C(α,γ)^(16)O reactions. The experimental setup,which includes an accelerator system with high stability and high intensity, a detector system, and a shielding material with low background, will be established during the above research. The current progress of JUNA will be given. | WeiPing Liu ZhiHong Li JiangJun He XiaoDong Tang Gang Lian Zhu An JianJun Chang Han Chen QingHao Chen XiongJun Chen ZhiJun Chen BaoQun Cui XianChao Du ChangBo Fu Lin Gan Bing Guo GuoZhu He Alexander Heger SuQing Hou HanXiong Huang Ning Huang BaoLu Jia LiYang Jiang Shigeru Kubono JianMin Li KuoAng Li Tao Li YunJu Li Maria Lugaro XiaoBing Luo HongYi Ma ShaoBo Ma DongMing Mei YongZhong Qian JiuChang Qin Jie Ren YangPing Shen Jun Su LiangTing Sun WanPeng Tan Isao Tanihata Shuo Wang Peng Wang YouBao Wang Qi Wu ShiWei Xu ShengQuan Yan LiTao Yang Yao Yang XiangQing Yu Qian Yue Sheng Zeng HuanYu Zhang Hui Zhang LiYong Zhang NingTao Zhang QiWei Zhang Tao Zhang XiaoPeng Zhang XueZhen Zhang ZiMing Zhang Wei Zhao Zuo Zhao Chao Zhou | 2016 | Science China(Physics,Mechanics & Astronomy)2016，59，4： | 3 |
| 6 | Adakitic rocks at convergent plate boundaries:Compositions and petrogenesis显示文摘Adakitic rocks are intermediate-acid magmatic rocks characterized by enrichment in light rare-earth elements,depletion in heavy rare-earth elements,positive to negligible Eu and Sr anomalies,and high La/Yb and Sr/Y ratios.Cenozoic adakitic rocks generated by partial melting of subducted oceanic crust(slab)under eclogite-facies conditions(i.e.,the original definition of“adakite”)occur mainly in Pacific Rim volcanic arcs(intra-oceanic,continental,and continental-margin island arcs),whereas those generated by partial melting of thickened lower crust occur mainly in Tethyan Tibetan collisional orogens.In volcanic arcs,adakitic melts derived from the melting of subducted oceanic crust metasomatize the mantle wedge to form a unique rock suite comprising adakite-adakite-type high-Mg andesite-Piip-type high-Mg andesite-Nb-rich basalt-boninite.This suite differs from the basalt-andesite-dacite-rhyolite suite formed from mantle wedge metasomatized by fluids derived from subducted oceanic crust.Previously published data indicate that partial melting of mafic rocks can generate adakitic magmas under pressure,temperature,and hydrous conditions of 1.2-3.0 GPa,800-1000℃,and 1.5-6.0 wt.%H_(2)O,respectively,leaving residual minerals of garnet and rutile with little or no plagioclase.Cenozoic Au and Cu deposits occur proximally to adakitic rocks,with host rocks of some deposits actually being adakitic rocks.Adakitic rocks thus have important implications for both deep-Earth dynamics and Cu-Au mineralization/exploration.Although studies of Cenozoic adakitic rocks have made many important advances,there remain weaknesses in some important areas such as their tectonic settings,petrogenesis,magma sources,melt-mantle interactions of pre-Cenozoic adakitic rocks,and their relationship with the onset of plate tectonics and crustal growth.Future research directions are likely to involve(1)the generation of adakitic magmas by experimental simulations of partial melting of different types of rock(including intermediate-acid rocks)and magma fractional crystallization at different temperatures and pressures,(2)the relationship between magma reservoir evolution and the formation of adakitic rocks,(3)the tectonic setting and petrogenesis of pre-Cenozoic adakitic rocks and related geodynamic processes,(4)interactions between slab melts and the mantle wedge,(5)the formation of Archean adakitic tonalite-trondhjemite-granodiorite and its link to the onset of plate tectonics and crustal growth,and(6)the relationship between the formation of adakitic rocks and metal mineralization in different tectonic settings. | Qiang Wang Lulu Hao Xiuzheng Zhang Jinsheng Zhou Jun Wang Qiwei Li Lin Ma Long Zhang Yue Qi Gongjian Tang Wei Dan Jingjing Fan | 2020 | Science China Earth Sciences2020，63，12： | 3 |
| 7 | Identification and characterization of genes involved in the jasmonate biosynthetic and signaling pathways in mulberry(Morus notabilis)显示文摘Jasmonate(JA) is an important phytohormone regulating growth, development, and environmental response in plants, particularly defense response against herbivorous insects. Recently, completion of the draft genome of the mulberry(Morus notabilis) in conjunction with genome sequencing of silkworm(Bombyx mori) provides an opportunity to study this unique plant‐herbivore interaction. Here, we identified genes involved in JA biosynthetic and signaling pathways in the genome of mulberry for the first time, with the majority of samples showing a tissue‐biased expression pattern. The analysis of the representative genes 12‐oxophytodienoic acid reductase(OPRs) and jasmonate ZIM‐domain(JAZs) was performed and the results indicated that the mulberry genome contains a relatively small number of JA biosynthetic and signaling pathway genes. A gene encoding animportant repressor, MnNINJA, was identified as an alternative splicing variant lacking an ethylene‐responsive element binding factor‐associated amphiphilic repression motif. Having this fundamental information will facilitate future functional study of JA‐related genes pertaining to mulberry‐silkworm interactions. | Qing Wang Bi Ma Xiwu Qi Qing Guo Xuwei Wang Qiwei Zeng Ningjia He | 2014 | Journal of Integrative Plant Biology2014，56，7： | 3 |
| 8 | Impact of Land Use Change on Vegetation Carbon Storage During Rapid Urbanization:A Case Study of Hangzhou,China显示文摘Land use changes have significant impacts on the carbon balance in an urban ecosystem.When there is rapid development in urbanizing regions,land use changes have a dramatic effect on vegetation carbon storage(VCS).This study investigates the impact of land use change on VCS in a period of rapid urbanization in Hangzhou,China.The results show that:1)from 2000 to 2015,land use in Hangzhou underwent huge changes,mainly reflected in decrease in cropland and wetland and the increased settlement.More than 34.58%of the land was transformed,and the land use changes are primarily characterized by a significant decrease in cropland due to the occupation by settlement.2)over the 15 years,changes in land use led to a decrease of 3.93×10^(5) t of VCS in the urban ecosystem.The large-scale transformation of cropland and wetland,which have a comparatively high carbon density,into land for settlement exerted a negative impact on VCS.3)The central city,which with the Circle-E/I/O mode,had the lowest comprehensive land use dynamic degree,leading to moderate land use change and an increase in VCS;Yuhang and Xiaoshan,which with Multicore-E/O/I mode and Fan-E/O/I modes,had a higher comprehensive land use dynamic degree,drastic changes in land use,and a decrease in VCS.This study proposes a reliable method of estimating changes in VCS,clarifies the relationship between land use change and VCS during rapid urbanization,and provides recommendations for sustainable urban development. | WANG Zhi XU Lihua SHI Yijun MA Qiwei WU Yaqi LU Zhangwei MAO Liwei PANG Enqi ZHANG Qi | 2021 | Chinese Geographical Science2021，31，2： | 3 |
| 9 | The C_(6)D_(6)detector system on the Back-n beam line of CSNS显示文摘Introduction The neutron capture cross sections are very important in the field of nuclear device design and basic physics research.Hydrogen-free liquid scintillator such as C_(6)D_(6)detectors are widely used in the neutron capture cross-sectional measurements for the low neutron sensitivity and fast time response.The Back-n white neutron source at China Spallation Neutron Source is the first spallation white neutron source in China,and it is suitable for neutron capture cross-sectional measurement.Materials and methods A C_(6)D_(6)detector system was built in the Back-n experimental station.The pulse height weighting technique was used to determine the system’s detection efficiency.The response to gamma rays of the C_(6)D_(6)detector was measured,and the energy resolution function was determined.Monte Carlo simulation with Geant4 code was carried out to get the weighting function of this C_(6)D_(6)detector system.Additionally,the systematic uncertainty of the weighting function was also determined.Conclusion According to the experimental and simulation results,this C_(6)D_(6)detector system can be used to measure neutron capture cross section. | Jie Ren Xichao Ruan Jie Bao Guangyuan Luan Wei Jiang Qi An Huaiyong Bai Ping Cao Qiping Chen Yonghao Chen Pinjing Cheng Zengqi Cui Ruirui Fan Changqing Feng Minhao Gu Fengqin Guo Changcai Han Zijie Han Guozhu He Yongcheng He Yuefeng He Hanxiong Huang Weiling Huang Xiru Huang Xiaolu Ji Xuyang Ji Haoyu Jiang Hantao Jing Ling Kang Mingtao Kang Bo Li Lun Li Qiang Li Xiao Li Yang Li Yang Li Rong Liu Shubin Liu Xingyan Liu Yinglin Ma Changjun Ning Binbin Qi Zhaohui Song Hong Sun Xiaoyang Sun Zhijia Sun Zhixin Tan Hongqing Tang Jingyu Tang Pengcheng Wang Qi Wang Taofeng Wang Yanfeng Wang Zhaohui Wang Zheng Wang Jie Wen Zhongwei Wen Qingbiao Wu Xiaoguang Wu Xuan Wu Likun Xie Yiwei Yang Han Yi Li Yu Tao Yu Yongji Yu Guohui Zhang Jing Zhang Linhao Zhang Liying Zhang Qingmin Zhang Qiwei Zhang Xianpeng Zhang Yuliang Zhang Zhiyong Zhang Yingtan Zhao Liang Zhou Zuying Zhou Danyang Zhu Kejun Zhu Peng Zhu | 2019 | Radiation Detection Technology and Methods2019，3，3： | 1 |
| 10 | The Impact of Atmospheric Deposition of Cadmium on Dominant Algal Species in the East China Sea显示文摘Cadmium(Cd) mainly derived from anthropogenic emissions can be transported through atmospheric pathway to marine ecosystem,affecting the phytoplankton community and primary productivity.In this study,we identified the toxicity threshold of Cd for phytoplankton under seawater conditions of the coastal East China Sea(ECS) through both laboratory and in situ mesocosm incubation experiments.The mesocosm experiment showed that Cd in low concentration(0.003 μg per μg chl a) was conducive to the growth of natural community and increased chl a productivity.In high concentration(0.03 μg per μg chl a) Cd acted as an inhibiting factor which decreased the total chl a productivity.The diatom community was found to be more sensitive to Cd toxicity than dinoflagellate,as the low concentration Cd showed toxicity to diatom but enhanced dinoflagellate growth.We noticed that the soluble Cd estimated from atmosphere deposition to the coastal ECS was below the toxicity threshold and the Cd deposition might promote phytoplankton growth in this region.In our laboratory experiments,adding Cd,similar to aerosol deposition,stimulated the growth of both dominant algal species Prorocentrum donghaiense Lu(dinoflagellate) and Skeletonema costatum(diatom).Adding Cd on a higher level inhibited the growth of both the species,but Skeletonema costatum seemed obviously more sensitive to toxicity.This indicates the potential impact of atmospheric deposition Cd on phytoplankton community succession in the ECS. | QUAN Qiwei CHEN Ying MA Qingwei WANG Fujiang MENG Xi WANG Bo | 2016 | Journal of Ocean University of China2016，15，2： | 1 |
| 11 | Cyan Droid: stable and effective energy inefficiency diagnosis for Android apps显示文摘Smartphones are an indispensable part of people's daily lives. Smartphone apps often use phone sensors to probe their users' physical environmental conditions to provide services. However, sensing operations can be energy-consumptive, and thus the obtained sensory data should be effectively utilized by apps for their users' benefits. Existing studies disclosed that many real-world smartphone apps have poor utilization of sensory data, and this causes serious energy waste. To diagnose such energy bugs, a recent technique GreenD roid automatically generates sensory data, tracks their propagation and analyzes their utilization in an app. However,we observe that GreenD roid's sensory data generation is random and this can negatively affect its stability and effectiveness. Our study reported that GreenD roid might miss energy bugs that require specific sensory data to manifest. To address this problem, we propose a novel approach to systematically generating multi-dimensional sensory data. For effective diagnosis, we also propose to consider app state changes at a finer granularity. We implemented our approach as a prototype tool CyanD roid, and evaluated it using four real-world Android apps and hundreds of their mutants. Our results confirmed that CyanD roid is more stable and effective in energy inefficiency diagnosis for sensory data underutilization issues. | Qiwei LI Chang XU Yepang LIU Chun CAO Xiaoxing MA Jian LU | 2017 | Science China(Information Sciences)2017，60，1： | 1 |
| 12 | Joint optimization of inspection-based and age-based preventive maintenance and spare ordering policies for single-unit systems显示文摘This paper presents a joint optimization policy of preventive maintenance(PM)and spare ordering for single-unit systems,which deteriorate subject to the delay-time concept with three deterioration stages.PM activities that combine a non-periodic inspection scheme with age-replacement are implemented.When the system is detected to be in the minor defective stage by an inspection for the first time,place an order and shorten the inspection interval.If the system has deteriorated to a severe defective stage,it is either repaired imperfectly or replaced by a new spare.However,an immediate replacement is required once the system fails,the maximal number of imperfect maintenance(IPM)is satisfied or its age reaches to a pre-specified threshold.In consideration of the spare’s availability as needed,there are three types of decisions,i.e.,an immediate or a delayed replacement by a regular ordered spare,an immediate replacement by an expedited ordered spare with a relative higher cost.Then,some mutually independent and exclusive renewal events at the end of a renewal cycle are discussed,and the optimization model of such a joint policy is further developed by minimizing the long-run expected cost rate to find the optimal inspection and age-replacement intervals,and the maximum number of IPM.A Monte-Carlo based integration method is also designed to solve the proposed model.Finally,a numerical example is given to illustrate the proposed joint optimization policy and the performance of the Monte-Carlo based integration method. | MA Weining ZHAO Fei LI Xin HU Qiwei SHANG Bingcong | 2022 | Journal of Systems Engineering and Electronics2022，33，5： | 1 |
| 13 | A new concept of endoscopic lung cancer resection: Single-direction thoracoscopic lobectomy显示文摘 | Lunxu Liu Guowei Che Qiang Pu Lin Ma Yigen Wu Qiwei Kan Xuepeng Zhuge Lu Shi | 2009 | Surgical Oncology2009，，2： | 1 |
| 14 | Methodology of Sports Science Research in China──Abstracted from the keynote Speech of China's 4th National Sports Science Conference Held on 8 December, 1992显示文摘According to the characteristics of sports science research and in the light of the current development of our times, the paper discussed the important role of methodology in sports science research. While reviewing the significant progress made in China in research methods of sports science, the paper also pointed out some deficiencies in methodology and in the applicstion of specific methods. The paper expolinded that the development of sports in our country had made high demands of our times on scientific research method. It also encouraged sports scientists to make every effort to improve methodology so as to establish and develop our own sports science school in China. | TIAN Maijiu MA Qiwei ZHANG Liwei TIAN Ye LU Yuanzhen PU Junzong ZHANG Mingli (54 years old, PhD. professor) | 1995 | 北京体育大学学报1995，18，S2： | 0 |
| 15 | The origin of arc basalts:New advances and remaining questions显示文摘Whether arc magmatism occurs above oceanic subduction zones is the forefront of studies on convergent plate margins.The most important petrologic issue related to the evolution of arc systems is the origin of arc magmatism,among which arc basalts are the most important one because they provide insights into mantle enrichment mechanism and crust-mantle interaction at oceanic subduction zones.Fluids or melts released either by dehydration or by melting of subducting oceanic slab infiltrate and metasomatize the overlying mantle wedge at varying depth,leading to the formation of source regions of arc basalts.Such processes make most of arc basalts commonly enriched in large ion lithosphile elements and light rare earth elements,but depleted in high-field strength elements and heavy rare earth elements.Small amounts of arc basalts are characterized by relatively high Nb contents or by Nb enrichment.Rare basalts with compositions similar to ocean island basalts or mid-ocean ridge basalt also occur in arc systems.For these peculiar rocks,it remains debated whether their source is affected by subduction-related components.During their ascent and before their eruption,arc basaltic magmas are subjected to crystal fractionation,mixing and crustal contamination.In addition to the contribution of subducting slab components to the mantle source of arc basalts,the materials above the subducting slab at forearc depths would have been transported either by drag or by subduction erosion into the subarc mantle and into the source of arc magmas.Heats and materials brought by corner flows also play important roles in the generation of arc basalts.Despite the important progresses made in recent studies of arc basalts,further efforts are needed to investigate subarc mantle metasomatism,material recycling,the formation of arc magma sources,geodynamic mechanism in generating arc basalts,and their implicationd s for the initiation of plate tectonics on Earth. | Yigang Xu Qiang Wang Gongjian Tang Jun Wang Hongyan Li Jinsheng Zhou Qiwei Li Yue Qi Pingping Liu Lin Ma Jingjing Fan | 2020 | Science China Earth Sciences2020，63，12： | 0 |
| 16 | Infection,pathology and interferon treatment of the SARS-CoV-2 Omicron BA.1 variant in juvenile,adult and aged Syrian hamsters显示文摘The new predominant circulating SARS-CoV-2 variant,Omicron,can robustly escape current vaccines and neutralizing antibodies.Although Omicron has been reported to have milder replication and disease manifestations than some earlier variants,its pathogenicity in different age groups has not been well elucidated.Here,we report that the SARS-CoV-2 Omicron BA.1 sublineage causes elevated infection and lung pathogenesis in juvenile and aged hamsters,with more body weight loss,respiratory tract viral burden,and lung injury in these hamsters than in adult hamsters.Juvenile hamsters show a reduced interferon response against Omicron BA.1 infection,whereas aged hamsters show excessive proinflammatory cytokine expression,delayed viral clearance,and aggravated lung injury.Early inhaled IFN-α2b treatment suppresses Omicron BA.1 infection and lung pathogenesis in juvenile and adult hamsters.Overall,the data suggest that the diverse patterns of the innate immune response affect the disease outcomes of Omicron BA.1 infection in different age groups. | Lunzhi Yuan Huachen Zhu Peiwen Chen Ming Zhou Jian Ma Xuan Liu Kun Wu Rirong Chen Qiwei Liu Huan Yu Lifeng Li Jia Wang Yali Zhang Shengxiang Ge Quan Yuan Qiyi Tang Tong Cheng Yi Guan Ningshao Xia | 2022 | Cellular & Molecular Immunology2022，19，12： | 0 |
| 17 | Dynamic changes in transposable element and gene methylation in mulberry (Morus notabilis) in response to Botrytis cinerea显示文摘DNA methylation has been proposed to regulate plant stress resistance.However,the dynamic changes in DNA methylation in woody plants and their correlations with pathogenic responses are not fully understood.Here,we present single-base maps of the DNA methylomes of mulberry(Morus notabilis)leaves that were subjected to a mock treatment or inoculation with Botrytis cinerea.Compared with the former,the latter showed decreased mCG and mCHG levels and increased mCHH levels.DNA methylation inhibitors reduced resistance gene methylation levels and enhanced mulberry resistance,suggesting that the hypomethylation of resistance genes affects mulberry resistance to B.cinerea.Virus-induced gene silencing of MnMET1 enhanced the expression of mulberry-resistance genes,thereby increasing the plant’s resistance to B.cinerea.We also found that MITEs play a dominant role in controlling DNA methylation levels.MITEs appear to be the main sources of 24-nt siRNAs that regulate gene expression through the RNA-directed DNA methylation pathway. | Youchao Xin Bi Ma Qiwei Zeng Wenmin He Meiling Qin Ningjia He | 2021 | Horticulture Research2021，8，1： | 0 |
| 18 | Room-temperature hydrogenation of halogenated nitrobenzenes over metal-organic-framework-derived ultra-dispersed Ni stabilized by N-doped carbon nanoneedles显示文摘Ultra-dispersed Ni nanoparticles(7.5 nm)on nitrogen-doped carbon nanoneedles(Ni@NCNs)were prepared by simple pyrolysis of Ni-based metal–organic-framework for selective hydrogenation of halogenated nitrobenzenes to corresponding anilines.Two different crystallization methods(stirring and static)were compared and the optimal pyrolysis temperature was explored.Ni@NCNs were systematically characterized by wide analytical techniques.In the hydrogenation of p-chloronitrobenzene,Ni@NCNs-600(pyrolyzed at 600°C)exhibited extraordinarily high performance with 77.9 h^(–1)catalytic productivity and>99%p-chloroaniline selectivity at full p-chloronitrobenzene conversion under mild conditions(90°C,1.5 MPa H2),showing obvious superiority compared with reported Ni-based catalysts.Notably,the reaction smoothly proceeded at room temperature with full conversion and>99%selectivity.Moreover,Ni@NCNs-600 afforded good tolerance to various nitroarenes substituted by sensitive groups(halogen,nitrile,keto,carboxylic,etc.),and could be easily recycled by magnetic separation and reused for 5 times without deactivation.The adsorption tests showed that the preferential adsorption of–NO2 on the catalyst can restrain the dehalogenation of p-chloronitrobenzene,thus achieving high p-chloroaniline selectivity.While the high activity can be attributed to high Ni dispersion,special morphology,and rich pore structure of the catalyst. | Yuemin Lin Yuanyuan Zhang Renfeng Nie Kai Zhou Yao Ma Mingjie Liu Dan Lu Zongbi Bao Qiwei Yang Yiwen Yang Qilong Ren Zhiguo Zhang | 2022 | Frontiers of Chemical Science and Engineering2022，16，12： | 0 |
| 19 | Spatial sight analysis of Hangzhou Xiaoyingzhou based on tourists’landscape preference显示文摘Tourist preferences are important for the high-quality planning and design of recreation spaces.The famous scenic locale of West Lake in Hangzhou,China,is used as an example in this study.Based on multi-source data(e.g.,online comments,and tourist photographs),we used content analysis,kernel density estimation,and image semantic segmentation technology to determine the spatial distribution of tourists’landscape preferences.We analyzed these spatial sight characteristics from the viewpoint,sight distance,and perspectives.The results show that tourists’landscape preferences are mainly concentrated on landscape architecture for recreation.The viewpoints of these preferences are concentrated in the north-south embankmentdfar beyond that of the east-west embankment.The preferences also show a spatial sequence in terms of sight distance,and the best visual effect is the open platform at the north and south islands of Xiaoyingzhou.From the perspective of vision,the degree of spatial openness in the tourists’landscape preferences is proportional to the distance of vision;the two factors have a convergent relationship.The discussion of the characteristics of tourists’landscape preference and space sight creation in Xiaoyingzhou provides a reference for the quality improvement of island recreation space. | Yiying Chen Qiwei Ma Lihua Xu Yijun Shi Zhangwei Lu Yaqi Wu Mao Feng | 2023 | Frontiers of Architectural Research2023，12，6： | 0 |
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