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| 1 | Strengths, weaknesses, opportunities and threats (SWOT) analysis of reinitiation into methamphetamine abusers: qualitative findings from an exploration of methamphetamine abusers in Shanghai, China显示文摘Background Despite high relapse rate among methamphetamine (MA) abusers, there still have been little empirical data to date detecting the risk factors related to craving and relapse from the perspective of MA abusers. Therefore, the aim of this study was to use qualitative research methods exploring the strengths, weaknesses, opportunities and threat factors that could facilitate or impede individuals' abstinence in a real-life context from the perspectives of MA abusers. Aim To use qualitative research methods exploring the strengths, weaknesses, opportunities and threat factors relating to individuals' abstinence in a real-life context. Method Semistructured interviews were conducted with 32 MA abusers recruited in Shanghai guided by open-ended questions on narrating the real-life catalysts and inhibitors related to craving, initiation, relapse and abstinence. All data were transcribed verbatim and analysed using a strengths, weaknesses, opportunities and threats (SWOT) analysis. Results The results of the SWOT analysis revealed that contextual factors including peer influence, prevalence and availability of MA, familiar venue of MA use, discrimination, sexual behaviours, alcohol, emotional states and their attitudes towards smoking MA were important factors that contribute to reinitiation and relapse. Surveillance systems, antidrug social workers, vocational skills trainings, moving to another city and family responsibility might serve as counter measures targeti叩 those mentioned weaknesses and threats above. Conclusion This SWOT analysis highlights the complex nature of relapse. Comprehensive interventions strengtheni叩 coping skills such as virtual reality techniques are desperately needed to facilitate individuals1 sustained abstinence. | Youwei Zhu Na Zhong Hang Su Xiaolu Ruan Jiayi Bao Lei Zhang Jiang Du Ding Xu Rongjie Ding Ke Xiao Min Zhao | 2019 | General Psychiatry2019，32，3： | 9 |
| 2 | Integration of a thermochemical energy system driven by solar energy and biomass for natural gas and power production显示文摘Energy systems with multi-energy product outputs driven by renewable energy sources are becoming increasingly popular.To satisfy the diversification of energy use forms in China,this study proposes a new thermochemical energy system driven by solar energy and biomass for natural gas and power production.In this system,syngas from solar-driven biomass gasification is used to synthesize natural gas,whereas the unreacted syngas is burned directly in a combined cycle for power generation.To adjust the production capacity of the system,a shift reaction was used to change the H_(2)/CO ratio in the syngas.The biomass gasification model was experimentally verified,and the thermodynamic performance of the system was studied numerically.The results showed that the production rate of natural gas,with a heat value of 714.88 k J/mol,was approximately 0.306 m^(3)-SNG/kg-bio,and the primary energy efficiency was 47%.The new system showed a good energy-saving potential of 15.29%.Parametric analysis indicated that an increase in the gasification temperature led to a reduction in the natural gas production and an increase in the power output of the system,with a maximum energy efficiency of 66.72%at gasification temperature of 1050°C.With an increase in the syngas share entering the transfer reactor,the natural gas production rate and energy efficiency of the system were improved with an optimum share of approximately 0.55,thereby facilitating the development and optimization of operation strategies.This study provides a promising way to increase the share of renewable energy instead of fossil fuels. | WU HaiFeng ZHANG BoWen QU WanJun XU RongJi LIU QiBin | 2022 | Science China(Technological Sciences)2022，65，6： | 2 |
| 3 | Effect of heavy metals on the stabilization of mercury(II) by DTCR in desulfurization solutions显示文摘 | Jiaai Hou Rongjie Lu Mingyang Sun Shams Ali Baig Tingmei Tang Lihua Cheng Xinhua Xu | 2012 | Journal of Hazardous Materials2012，，： | 1 |
| 4 | Stabilization of mercury in flue gas desulfurization gypsum from coal-fired electric power plants with additives显示文摘 | Mingyang Sun Jiaai Hou Tingmei Tang Rongjie Lu Lihua Cheng Xinhua Xu | 2012 | Fuel Processing Technology2012，，： | 1 |
| 5 | Enhanced Hg 2+ removal and Hg 0 re-emission control from wet fuel gas desulfurization liquors with additives显示文摘 | Tingmei Tang Jiang Xu Rongjie Lu Jingjing Wo Xinhua Xu | 2010 | Fuel2010，，12： | 1 |
| 6 | A novel protein RASON encoded by a lncRNA controls oncogenic RAS signaling in KRAS mutant cancers显示文摘Mutations of the RAS oncogene are found in around 30%of all human cancers yet direct targeting of RAS is still considered clinically impractical except for the KRAS^(G12C)mutant.Here we report that RAS-ON(RASON),a novel protein encoded by the long intergenic non-protein coding RNA 00673(LINC00673),is a positive regulator of oncogenic RAS signaling.RASON is aberrantly overexpressed in pancreatic ductal adenocarcinoma(PDAC)patients,and it promotes proliferation of human PDAC cell lines in vitro and tumor growth in vivo.CRISPR/Cas9-mediated knockout of Rason in mouse embryonic fibroblasts inhibits KRAS-mediated tumor transformation.Genetic deletion of Rason abolishes oncogenic KRAS-driven pancreatic and lung cancer tumorigenesis in LSL Kras^(G12D);Trp53R172H/+mice.Mechanistically,RASON directly binds to KRAS^(G12D)/V and inhibits both intrinsic and GTPase activating protein(GAP)-mediated GTP hydrolysis,thus sustaining KRAS^(G12D/V)in the GTP-bound hyperactive state.Therapeutically,deprivation of RASON sensitizes KRAS mutant pancreatic cancer cells and patient-derived organoids to EGFR inhibitors.Our findings identify RASON as a critical regulator of oncogenic KRAS signaling and a promising therapeutic target for KRAS mutant cancers. | Rongjie Cheng Fanying Li Maolei Zhang Xin Xia Jianzhuang Wu Xinya Gao Huangkai Zhou Zhi Zhang Nunu Huang Xuesong Yang Yaliang Zhang Shunli Shen Tiebang Kang Zexian Liu Feizhe Xiao Hongwei Yao Jianbo Xu Chao Yan Nu Zhang | 2023 | Cell Research2023，33，1： | 1 |
| 7 | A Vapor Injector-Based NovelRegenerative Organic Rankine Cycle 显示文摘 | XU Rongji HE Yaling | 2011 | Applied Ther-mal Engineering2011，31，67： | 1 |
| 8 | Waveform-controlled terahertz radiation from the air filament produced by few- cycle laser pulses 显示文摘 | Bai Ya Song Liwei Xu Rongjie | 2012 | Physical Review Letters2012，108，25： | 1 |
| 9 | Performance ofMoFe2 04 -NiFe2 04/Fullerene-added nano-oil appliedin the domestic refrigerator compressors 显示文摘 | Tao Jia Ruixiang Wang Rongji Xu | 2014 | InternationalJournal of Refrigeration2014，45，： | 1 |
| 10 | Testing and Modeling of the Dynamic Response Characteristics of Pulsating Heat Pipes during the Start-up Process显示文摘Pulsating heat pipes(PHPs) are two-phase heat transfer heat pipes with high heat transfer capability and simple structure. Heating power is an important factor that affects the start-up response characteristics of PHPs. The operational characteristics during the start-up and stable operating stages were studied through experiments, and the corresponding dynamic response model under a specified heating power was established based on experimental data and flow pattern in the tube. The starting time, starting temperature, and dynamic response characteristic parameters at a certain heating power were calculated by the dynamic response model. The response characteristics of working fluid during the stable operation of PHPs were deduced based on the dynamic response curve of PHPs during the non-operational and stable operation stages. The response characteristics of PHPs for the step effect(given heating power) were quantitatively described by amplification factor K and time constant τ, thereby presenting the basis for the study on heat and mass transfer mechanisms of PHPs from non-operational to steady operation stage. Results showed that the minimum thermal resistance and the minimum time constant of the PHP are approximately 0.28 °C/W and 75, respectively, obtained at a heating power of 160 W. Moreover, these results indicated that the dynamic response of PHPs demonstrates a favourable performance and rapidly reaches another stable working state when their heat transfer performance is stable. However, the dynamic response time constant of pure fluids decreases when the quantity of the liquid working fluid in the PHP decreases with the increase in heating power. | XU Rongji CHEN Hao WU Qingping XU Shuhui WANG Ruixiang | 2019 | Journal of Thermal Science2019，28，1： | 1 |
| 11 | MicroRNA-205 functions as a tumor suppressor in human glioblastoma cellsby targeting VEGF-A显示文摘 | Xiao Yue Peiguo Wang Jun Xu Yufang Zhu Guan Sun Qi Pang Rongjie Tao | 2012 | Oncology Reports2012，，4： | 1 |
| 12 | Enhanced Hg^2+ removal and Hg^0 re-emission control from wet fuel gas desulfurization liquors with additives 显示文摘 | Tang Tingmei Xu Jiang Lu Rongjie | 2010 | Fuel2010，，89： | 1 |
| 13 | A Vapor Injector-based Novel Regenerative Organic Rankine Cycle 显示文摘 | XU Rongji HE Yaling | 2011 | Applied Thermal Engineering2011，31，67： | 1 |
| 14 | Synergistic effects of dodecane-castor oil acid mixture on the flotation responses of low-rank coal:A combined simulation and experimental study显示文摘The utilization of an appropriate collector or surfactant is crucial for the beneficiation of low-rank coal.However,in previous studies,the selection of surfactants was primarily based on flotation procedures,which hinders the understanding of the interaction mechanism between surfactant groups and oxygen-containing functional groups at the surface of low-rank coal.In this study,we investigate the flotation of low-rank coal in the presence of a composite collector by using a combined theoretical and experimental approach.The maximum flotation mass recovery achieved was 82.89%using a 3:1 mixture of dodecane and castor oil acid.Fourier-transform infrared and X-ray photoelectron spectroscopic analyses showed that castor oil acid was effectively adsorbed onto the surface of low-rank coal,enhancing the hydrophobicity of the coal.In addition,the diffusion coefficient of water molecules in the water-composite collector-coal system was greater than that in the dodecane system.Moreover,due to the presence of castor oil acid in the flotation process,the adsorption distance of dodecane and low-rank coal became shorter.Molecular dynamics simulations revealed that the diffusion and interaction of surfactant molecules at the interface of low-rank coal particles and water was enhanced because the adsorption of the dodecane-castor oil acid mixture is primarily controlled by hydrogen bonds and electrostatic attraction.Based on these results,a better surfactant for flotation of low-rank coal is also proposed. | Fen Xu Shiwei Wang Rongjie Kong Chengyong Wang | 2023 | International Journal of Mining Science and Technology2023，33，5： | 0 |
| 15 | Heat Leakage Numerical Investigation of a Compound Parabolic ConcentratorPulsating Heat Pipe Solar Collector显示文摘As a new type of equipment for solar medium temperature utilization, the compound parabolic concentrator-pulsating heat pipe solar collector(CPC-PHPSC) uses pulsating heat pipe(PHP) as an endotherm, which can realize efficient energy conversion. The design of proper concentration ratio of compound parabolic concentrator(CPC) ensures that the incident sunlight can be concentrated on the evaporator section surface of PHP without solar tracking system. The objective of the present work is to study the influence of solar radiation intensity, air speed, material thickness(glass and insulation board) and tilt angle on the thermal performance of the new collector, which is difficult to control in the experiment. The heat leakage process and characteristics of the CPC-PHPSC were numerically studied by establishing a 3D numerical model of the collector unit. The results show that the theoretical collector efficiency of CPC-PHPSC reaches 74.5%, which is consistent with the experimental results. During operation, the heat collection performance is the best when the tilt angle is 45° and the solar radiation intensity is 1000 W/m^(2), while the excessive air speed will increase the convective heat loss. Increasing the thickness of insulation board and glass has little effect on the collector efficiency. | XU Rongji CHEN Jingyan ZHANG Xiaohui WANG Ruixiang XU Shuhui | 2022 | Journal of Thermal Science2022，31，5： | 0 |
| 16 | Two-photon live imaging of direct glia-to-neuron conversion in the mouse cortex显示文摘Over the past decade,a growing number of studies have reported transcription factor-based in situ reprogramming that can directly conve rt endogenous glial cells into functional neurons as an alternative approach for n euro regeneration in the adult mammalian central ne rvous system.Howeve r,many questions remain regarding how a terminally differentiated glial cell can transform into a delicate neuron that forms part of the intricate brain circuitry.In addition,concerns have recently been raised around the absence of astrocyte-to-neuron conversion in astrocytic lineage-tra cing mice.In this study,we employed repetitive two-photon imaging to continuously capture the in situ astrocyte-to-neuron conversion process following ecto pic expression of the neural transcription factor NeuroD1 in both prolife rating reactive astrocytes and lineage-tra ced astrocytes in the mouse cortex.Time-lapse imaging over several wee ks revealed the ste p-by-step transition from a typical astrocyte with numero us short,tapered branches to a typical neuro n with a few long neurites and dynamic growth cones that actively explored the local environment.In addition,these lineage-converting cells were able to migrate ra dially or to ngentially to relocate to suitable positions.Furthermore,two-photon Ca2+imaging and patch-clamp recordings confirmed that the newly generated neuro ns exhibited synchronous calcium signals,repetitive action potentials,and spontaneous synaptic responses,suggesting that they had made functional synaptic connections within local neural circuits.In conclusion,we directly visualized the step-by-step lineage conversion process from astrocytes to functional neurons in vivo and unambiguously demonstrated that adult mammalian brains are highly plastic with respect to their potential for neuro regeneration and neural circuit reconstruction. | Zongqin Xiang Shu He Rongjie Chen Shanggong Liu Minhui Liu Liang Xu Jiajun Zheng Zhouquan Jiang Long Ma Ying Sun Yongpeng Qin Yi Chen Wen Li Xiangyu Wang Gong Chen Wenliang Lei | 2024 | Neural Regeneration Research2024，19，8： | 0 |
| 17 | Bioprocess-inspired Actin Biomineralized Hematite Mesocrystals for Energy Storage显示文摘Biomineralization is a biological process of synthesizing inorganic minerals within organisms.It has been found that intracellular proteins are involved in the room temperature synthesis process of anatase Ti O2in living mussels.Here,we used intracellular actin to synthesize hematite by biomineralization.Biomineralized hematite has a nano spindle structure with a particle size of approximately 150 nm.The microstructure indicates that the prepared hematite is a mesocrystals composed of ordered arrangement and assembly of primary nanoparticles.In addition,hematite mesocrystals exhibit good lithium storage performance as electrode materials for lithium batteries.The discharge specific capacity of the battery remained at 560.7 m Ah·g^(-1)after 130 cycles at a current density of 200 m A·g^(-1).This work expands the synthesis methods of hematite by biomineralization,and provides a new strategy for preparing inorganic materials by intracellular proteins. | XU Wei ZHAO Chao XIE Jingjing WANG Rongjie | 2023 | Journal of Wuhan University of Technology(Materials Science)2023，38，6： | 0 |
| 18 | Amyloid precursor-like protein 2 C-terminal fragments upregulate S100A9 gene and protein expression in BV2 cells显示文摘The murine microglial cell line BV2 has neuroprotective effects, but is toxic to neurons by secreting inflammatory cytokines, and is an important target in the treatment of nerve inflammation and neurodegenerative diseases. In the present study, we observed the effects of transfecting three amyloid precursor-like protein 2(APLP2) C-terminal fragments(CTFs; C57, C50 and C31) in the p EGFP-N1 vector on S100A9 expression in BV2 cells. Reverse transcription-PCR, western blot assay and immunocytochemistry revealed that S100A9 protein and m RNA expression was greater in BV2 cells after CTF transfection than after mock transfection with an empty vector. Furthermore, transfection of full-length APLP2-751 resulted in low levels of S100A9 protein expression. Our results show that APLP2-CTFs upregulate S100A9 protein and m RNA expression in BV2 cells, and identify a novel pathway involved in neuronal injury and apoptosis, and repair and protection in Alzheimer's disease. | Guangzhe Li Hui Chen Lin Cheng Rongjie Zhao Junchang Zhao Yanji Xu | 2014 | Neural Regeneration Research2014，9，21： | 0 |
| 19 | Homogenization Function of Microchannel on Heat Absorber with Compound Parabolic Concentrator显示文摘Microchannels offer unique advantages on heat transfer performance. In this paper, microchannels are applied to the compound parabolic concentrator(CPC) system. A multi-physical field coupling model based on Finite Element Method is proposed to investigate the homogenization effect of the microchannel heat absorber on the CPC non-uniform concentration. The energy conversion process from optics to heat is simulated using TracePro software, and the heat transfer processes in the microchannel are computed by Fluent using user defined functions(UDF). It is found that the microchannels behave well on weakening the influence of the nonuniformity solar heat flux on the performance of the CPC. The temperature nonuniformity of the outlet section is less than 10^(-3) in the direction of fluid flow caused by the microchannel, although the maximum surface heat flux inhomogeneity of the microchannel reaches 2.3. The peak value of the heat flux on the surface of the absorber changes from double peak to single peak, and moves to the edge, resulting in more uneven heat flux distribution with the increase of the incident angle within the acceptance semi-angle of the CPC. The result of TracePro clearly shows that when the concentration ratio is less than 5, the heat flux nonuniformity on the surface of the absorber decreases with the increase in concentration ratio. It was interestingly found that the temperature distribution of the heat transfer fluid has weak sensitivity to the changes of truncation ratio. This work provides a way to design a CPC solar collector. | WANG Xueqing WU Haifeng MA Yusen WANG Suilin XU Rongji | 2022 | Journal of Thermal Science2022，31，6： | 0 |
| 20 | Unprecedent green macroalgae bloom:mechanism and implication to disaster prediction and prevention显示文摘Green macroalgae bloom(GMB),with the dominant species of Ulva prolifera,has regularly occurred since 2007 along the China coast.Although disaster prevention and control achieved favorable results in 2020,the satellite-observed GMB annual maximum coverage(AMC)rebounded sharply in 2021 to an unprecedented level.The reasons for this rebound and the significant interannual variability over past 15 years are still open questions.Here,by using long-term time-series(2007-2022)optical and Synthetic Aperture Radar satellite observations(1000+scenes),meteorological data and water quality statistics,the mechanism analysis was performed by exploring effects from natural factors and human activities.Two key determinants for AMC are successfully identified from numerous potential factors which are the macroalgae distribution in a key area(the Subei Shoal)during a critical period(from April to May 20)and the nutrient availability.Furthermore,by using these two parameters,a novel model for AMC prediction(R^(2)=0.87,p<0.01)is proposed and independently validated,which can reasonably explain the significant interannual variability(2014-2021)and agree well with the latest observation in 2022(percentage difference 12%).Finally,suggestions are proposed for future disaster prevention and alleviation.This work may aid future bloom prediction and management measure optimization. | Mengmeng Cao Xuyan Li Tingwei Cui Xinliang Pan Yan Li Yanlong Chen Ning Wang Yanfang Xiao Xingai Song Yuzhu Xu Runa A Bing Mu Song Qing Rongjie Liu Wenjing Zhao Yuhai Bao Jie Zhang Lan Wei | 2023 | International Journal of Digital Earth2023，16，1： | 0 |
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