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| 1 | Pregnancy and inflammatory bowel diseases: Current perspectives, risks and patient management显示文摘Inflammatory bowel diseases(IBD) are chronic idiopathic inflammatory conditions characterized by relapsing and remitting episodes of inflammation which can affect several different regions of the gastrointestinal tract, but also shows extra-intestinal manifestations. IBD is most frequently diagnosed during peak female reproductive years, with 25% of women with IBD conceiving after their diagnosis. While IBD therapy has improved dramatically with enhanced surveillance and more abundant and powerful treatment options, IBD disease can have important effects on pregnancy and presents several challenges for maintaining optimal outcomes for mothers with IBD and the developing fetus/neonate. Women with IBD, the medical team treating them(both gastroenterologists and obstetricians/gynecologists) must often make highly complicated choices regarding conception, pregnancy, and post-natal care(particularly breastfeeding) related to their choice of treatment options at different phases of pregnancy as well as post-partum. This current review discusses current concerns and recommendations for pregnancy duringIBD and is intended for gastroenterologists, general practitioners and IBD patients intending to become,(or already) pregnant, and their families. We have addressed patterns of IBD inheritance, effects of IBD on fertility and conception(in both men and women), the effects of IBD disease activity on maintenance of pregnancy and outcomes, risks of diagnostic procedures during pregnancy and potential risks and complications associated with different classes of IBD therapeutics. We also have evaluated the clinical experience using 'top-down' care with biologics, which is currently the standard care at our institution. Post-partum care and breastfeeding recommendations are also addressed. | Pegah Hosseini-Carroll Monica Mutyala Abhishek Seth Shaheen Nageeb Demiana Soliman Moheb Boktor Ankur Sheth Jonathon Chapman James Morris Paul Jordan Kenneth Manas Felix Becker Jonathan Steven Alexander | 2015 | World Journal of Gastrointestinal Pharmacology and Therapeutics2015，6，4： | 4 |
| 2 | Partial growth-hormone insensitivity: The role of growth-hormone receptor mutations in idiopathic short stature显示文摘 | Audrey D. Goddard Patrick Dowd Steven Chernausek Mitchell Geffner Joseph Gertner Raymond Hintz Nancy Hopwood Selna Kaplan Leslie Plotnick Alan Rogol Robert Rosenfield Paul Saenger Nellie Mauras Richard Hershkopf Morris Angulo Kenneth Attie | 1997 | The Journal of Pediatrics1997，，1： | 2 |
| 3 | Efficacy and safety of standard and anti-reflux self-expanding metal stent: A systematic review and meta-analysis of randomized controlled trials显示文摘BACKGROUND Self-expanding metal stents are the main palliative treatment modality for unresectable esophageal cancer. Gastroesophageal reflux is a common adverse outcome after placement of esophageal stent for cancer involving the gastroesophageal junction and the gastric cardia. Anti-reflux stents with valve have been designed to prevent the acid reflux. The superiority of anti-reflux stent over standard stent in preventing gastroesophageal reflux has not been established well. This study compares the anti-reflux stent and the standard stent in terms of their efficacy to prevent acid reflux.AIM To compare the standard and the anti-reflux stents in terms of their efficacy,safety, and complications.METHODS The meta-analysis included 8 randomized clinical trials(RCTs) to compare pooled outcomes of total 395 patients. Primary outcomes include improvement in reflux symptoms and dysphagia score. Secondary outcomes include complications of stent migration, occlusion, and bleeding.RESULTS A total of eight RCTs were included in the meta-analysis. Compared to the standard stent, the anti-reflux stent showed a trend towards reduction in the dysphagia score without reaching a statistical significance [Standardized mean difference(SMD):-0.33(-0.71, 0.05); P = 0.09, I2: 37%]. There was no statistical difference in the gastrointestinal reflux(GER) scores between the two types of stents [SMD:-0.17(-0.78, 0.45); P = 0.008, I2: 74%]. Compared to standard stent,anti-reflux stent showed no difference in the risk of stent migration [OR: 1.37(0.66, 2.83); P = 0.40, I2: 0 %], bleeding [OR: 1.43(0.40, 5.13); P = 0.59, I2: 0 %], and obstruction [OR: 1.66(0.60, 4.60); P = 0.33, I2: 0 %].CONCLUSION Traditional self-expanding standard esophageal stent and anti-reflux stent with valve are similar in terms of outcomes and complications. | Sudha Pandit Hrishikesh Samant James Morris Steven J Alexander | 2019 | World Journal of Gastrointestinal Endoscopy2019，11，4： | 2 |
| 4 | Combined Resection and Radiofrequency Ablation for Advanced Hepatic Malignancies: Results in 172 Patients显示文摘 | Timothy M. Pawlik MD MPH Francesco Izzo MD Deborah S. Cohen MS Jeffery S. Morris PhD Steven A. Curley MD | 2003 | Annals of Surgical Oncology2003，，9： | 2 |
| 5 | DIVA: a Visualization System for Exploring Document Databases for Technology Forecasting显示文摘 | Steven Morris Camille De Yong Zheng Wu Sinan Satman Dagmawi Yemenu | 2002 | Computer and Industrial Engineering2002，43，： | 1 |
| 6 | Phase I pharmacokinetic and biodistribution study with escalating doses of 223 Ra-dichloride in men with castration-resistant metastatic prostate cancer显示文摘 | Jorge A. Carrasquillo Joseph A. O’Donoghue Neeta Pandit-Taskar John L. Humm Dana E. Rathkopf Susan F. Slovin Matthew J. Williamson Kristine Lacuna Anne-Kirsti Aksnes Steven M. Larson Howard I. Scher Michael J. Morris | 2013 | European Journal of Nuclear Medicine and Molecular Imaging2013，，9： | 1 |
| 7 | Hedgehog signaling displays a biphasic expression pattern during intestinal injury and repair显示文摘 | Rui Liang Peter Morris Steven S.C. Cho Helen E. Abud Xianqing Jin Wei Cheng | 2012 | Journal of Pediatric Surgery2012，，12： | 1 |
| 8 | DEATH IN THE OPERATING ROOM: AN ANALYSIS OF A MULTI-CENTER EXPERIENCE显示文摘 | David B. Hoyt Eileen M. Bulger M. Margaret Knudson John Morris Ralph lerardi Harvey J. Sugerman Steven R. Shackford Jeffery Landercasper Robert J. Winchell Gregory Jurkovich Susan C. Coffey Michael Chang Keith F. O?Malley James Lowry Gino T. Trevisani Tho | 1994 | The Journal of Trauma: Injury Infection and Critical Care1994，，3： | 1 |
| 9 | Feasibility of pancreatectomy following high-dose proton therapy for unresectable pancreatic cancer显示文摘AIM To review surgical outcomes for patients undergoing pancreatectomy after proton therapy with concomitant capecitabine for initially unresectable pancreatic adenocarcinoma.METHODS From April 2010 to September 2013,15 patients with initially unresectable pancreatic cancer were treated withproton therapy with concomitant capecitabine at 1000 mg orally twice daily. All patients received 59.40 Gy(RBE) to the gross disease and 1 patient received 50.40 Gy(RBE) to high-risk nodal targets. There were no treatment interruptions and no chemotherapy dose reductions. Six patients achieved a radiographic response sufficient to justify surgical exploration,of whom 1 was identified as having intraperitoneal dissemination at the time of surgery and the planned pancreatectomy was aborted. Five patients underwent resection. Procedures included:Laparoscopic standard pancreaticoduodenectomy(n = 3),open pyloris-sparing pancreaticoduodenectomy(n = 1),and open distal pancreatectomy with irreversible electroporation(IRE) of a pancreatic head mass(n = 1). RESULTS The median patient age was 60 years(range,51-67). The median duration of surgery was 419 min(range,290-484),with a median estimated blood loss of 850 cm^3(range,300-2000),median ICU stay of 1 d(range,0-2),and median hospital stay of 10 d(range,5-14). Three patients were re-admitted to a hospital within 30 d after discharge for wound infection(n = 1),delayed gastric emptying(n = 1),and ischemic gastritis(n = 1). Two patients underwent R0 resections and demonstrated minimal residual disease in the final pathology specimen. One patient,after negative pancreatic head biopsies,underwent IRE followed by distal pancreatectomy with no tumor seen in the specimen. Two patients underwent R2 resections. Only 1 patient demonstrated ultimate local progression at the primary site. Median survival for the 5 resected patients was 24 mo(range,10-30).CONCLUSION Pancreatic resection for patients with initially unresectable cancers is feasible after high-dose [59.4 Gy(RBE)] proton radiotherapy with a high rate of local control,acceptable surgical morbidity,and a median survival of 24 mo. | Kathryn E Hitchcock R Charles Nichols Christopher G Morris Debashish Bose Steven J Hughes John A Stauffer Scott A Celinski Elizabeth A Johnson Robert A Zaiden Nancy P Mendenhall Michael S Rutenberg | 2017 | World Journal of Gastrointestinal Surgery2017，9，4： | 1 |
| 10 | Wet ashing of some biological samples in a microwave oven显示文摘 | ABU-SAMRA A STEVEN MORRIS J KOIRTYOHANN S R | 1975 | Anal Chem1975，47，8： | 1 |
| 11 | Inheritance and effect on ripening of antisense polygalacturonase genes in transgenic tomatoes显示文摘 | Christopher J. S. Smith Colin F. Watson Peter C. Morris Colin R. Bird Graham B. Seymour Julie E. Gray Christine Arnold Gregory A. Tucker Wolfgang Schuch Steven Harding Donald Grierson | 1990 | Plant Molecular Biology1990，，3： | 1 |
| 12 | Magnesium Intake and Incidence of Metabolic Syndrome Among Young Adults显示文摘 | Ka He Kiang Liu Martha L. Daviglus Steven J. Morris Catherine M. Loria Linda Van Horn David R. Jacobs Peter J. Savage | 2006 | Circulation2006，，13： | 1 |
| 13 | Validity and Reliability of the Alzheimer?s Disease Cooperative Study-Clinical Global Impression of Change显示文摘 | Lon S. Schneider Jason T. Olin Rachelle S. Doody Christopher M. Clark John C. Morris Barry Reisberg Frederick A. Schmitt Michael Grundman Ronald G. Thomas Steven H. Ferris | 1997 | Alzheimer Disease & Associated Disorders1997，，： | 1 |
| 14 | Composition and flavor quality of fresh market tomatoes as influenced by some postharvest handling procedures显示文摘 | KADDER A A MORRIS L L STEVENS M A ALBRIGHT-HOLTON M | 1978 | Journal of the American Society for Horticultural Science1978，103，： | 1 |
| 15 | Levels and trends of brominated flame retardants in the European environment显示文摘 | Robin J. Law Colin R. Allchin Jacob de Boer Adrian Covaci Dorte Herzke Peter Lepom Steven Morris Jacek Tronczynski Cynthia A. de Wit | 2005 | Chemosphere2005，，2： | 1 |
| 16 | Effect of fruit ripeness when picked on flavor and composition of fresh market tomatoes显示文摘 | KADER A A STEVENS M A ALBRIGHT-HOLTON M MORRIS L L ALGAZI M | 1977 | Journal of the American Society for Horticultural Science1977，102，： | 1 |
| 17 | Diet, fecal bile acids, and neutral sterols in carcinoma of the colon显示文摘 | Morry Moskovitz MD Colin White MD Roy N. Barnett MD Sydney Stevens RN Edith Russell AB David Vargo MS Dr. Martin H. Floch MD | 1979 | Digestive Diseases and Sciences1979，，10： | 1 |
| 18 | Standardized uptake value by positron emission tomography/computed tomography as a prognostic variable in metastatic breast cancer显示文摘 | Patrick G. Morris Gary A. Ulaner Anne Eaton Maurizio Fazio Komal Jhaveri Sujata Patil Laura Evangelista Joseph Y. Park Cristian Serna‐Tamayo Jane Howard Steven Larson Clifford A. Hudis Heather L. McArthur Maxine S. Jochelson | 2012 | Cancer2012，，22： | 1 |
| 19 | Combined Resection and Radiofrequency Ablation for Advanced Hepatic Malignancies: Results in 172 Patients显示文摘 | Timothy M. Pawlik MD MPH Francesco Izzo MD Deborah S. Cohen MS Jeffery S. Morris PhD Steven A. Curley MD | 2003 | Annals of Surgical Oncology2003，，9： | 1 |
| 20 | Fate of heavy metals and radioactive metals in gasification of sewage sludge 显示文摘 | MARRERO T W MCAULEY B P SUTTERLIN W R STEVEN MORRIS J MANAHAN S E | 2004 | Waste Manage2004，24，2： | 1 |
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