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| 1 | Safety of once‐daily insulin detemir in patients with type 2 diabetes treated with oral hypoglycemic agents in routine clinical practice (在常规临床实践中使用口服降糖药治疗的2型糖尿病患者每日一次使用地特胰岛素治疗的安全性)显示文摘 | Stuart Ross Grzegorz Dzida Qiuhe Ji Marcel Kaiser Robert Ligthelm Luigi Meneghini Avideh Nazeri Domingo Orozco‐Beltran Changyu Pan Anne Louise Svendsen | 2014 | Journal of Diabetes2014，，3： | 18 |
| 2 | A history of high-power laser research and development in the United Kingdom显示文摘The first demonstration of laser action in ruby was made in 1960 by T.H.Maiman of Hughes Research Laboratories,USA.Many laboratories worldwide began the search for lasers using different materials,operating at different wavelengths.In the UK,academia,industry and the central laboratories took up the challenge from the earliest days to develop these systems for a broad range of applications.This historical review looks at the contribution the UK has made to the advancement of the technology,the development of systems and components and their exploitation over the last 60 years. | Colin N.Danson Malcolm White John R.M.Barr Thomas Bett Peter Blyth David Bowley Ceri Brenner Robert J.Collins Neal Croxford A.E.Bucker Dangor Laurence Devereux Peter E.Dyer Anthony Dymoke-Bradshaw Christopher B.Edwards Paul Ewart Allister I.Ferguson John M.Girkin Denis R.Hall David C.Hanna Wayne Harris David I.Hillier Christopher J.Hooker Simon M.Hooker Nicholas Hopps Janet Hull David Hunt Dino A.Jaroszynski Mark Kempenaars Helmut Kessler Sir Peter L.Knight Steve Knight Adrian Knowles Ciaran L.S.Lewis Ken S.Lipton Abby Littlechild John Littlechild Peter Maggs Graeme P.A.Malcolm OBE Stuart P.D.Mangles William Martin Paul McKenna Richard O.Moore Clive Morrison Zulfikar Najmudin David Neely Geoff H.C.New Michael J.Norman Ted Paine Anthony W.Parker Rory R.Penman Geoff J.Pert Chris Pietraszewski Andrew Randewich Nadeem H.Rizvi Nigel Seddon MBE Zheng-Ming Sheng David Slater Roland A.Smith Christopher Spindloe Roy Taylor Gary Thomas John W.G.Tisch Justin S.Wark Colin Webb S.Mark Wiggins Dave Willford Trevor Winstone | 2021 | High Power Laser Science and Engineering2021，9，2： | 5 |
| 3 | Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial显示文摘 | Michael P Manns John G McHutchison Stuart C Gordon Vinod K Rustgi Mitchell Shiffman Robert Reindollar Zachary D Goodman Kenneth Koury Mei-Hsiu Ling Janice K Albrecht | 2001 | The Lancet2001，，9286： | 4 |
| 4 | Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial显示文摘 | Michael P Manns John G McHutchison Stuart C Gordon Vinod K Rustgi Mitchell Shiffman Robert Reindollar Zachary D Goodman Kenneth Koury Mei-Hsiu Ling Janice K Albrecht | 2001 | The Lancet . 2001 (9286)2001，，9286： | 4 |
| 5 | Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial显示文摘 | Michael P Manns John G McHutchison Stuart C Gordon Vinod K Rustgi Mitchell Shiffman Robert Reindollar Zachary D Goodman Kenneth Koury Mei-Hsiu Ling Janice K Albrecht | 2001 | 2001 (9286)2001，，9286： | 4 |
| 6 | Sofosbuvir with pegylated interferon alfa-2a and ribavirin for treatment-naive patients with hepatitis C genotype-1 infection (ATOMIC): an open-label, randomised, multicentre phase 2 trial显示文摘 | Kris V Kowdley Eric Lawitz Israel Crespo Tarek Hassanein Mitchell N Davis Michael DeMicco David E Bernstein Nezam Afdhal John M Vierling Stuart C Gordon Jane K Anderson Robert H Hyland Hadas Dvory-Sobol Di An Robert G Hindes Efsevia Albanis William T Symo | 2013 | The Lancet2013，，9883： | 3 |
| 7 | Low virological response and high relapse rates in hepatitis C genotype 1 patients with advanced fibrosis despite adequate therapeutic dosing显示文摘 | Wendy S.C. Cheng Stuart K. Roberts Geoffrey McCaughan William Sievert Martin Weltman Darrell Crawford William Rawlinson Philippa S. Marks James Thommes Bishoy Rizkalla Motoko Yoshihara Gregory J Dore | 2010 | Journal of Hepatology2010，，4： | 2 |
| 8 | Vitamin D status does not predict sustained virologic response or fibrosis stage in chronic hepatitis C genotype 1 infection显示文摘 | Matthew T. Kitson Gregory J. Dore Jacob George Peter Button Geoffrey W. McCaughan Darrell H.G. Crawford William Sievert Martin D. Weltman Wendy S. Cheng Stuart K. Roberts | 2012 | Journal of Hepatology2012，，： | 2 |
| 9 | THE PREDICTIVE VALUE OF DONOR LIVER BIOPSIES FOR THE DEVELOPMENT OF PRIMARY NONFUNCTION AFTER ORTHOTOPIC LIVER TRANSPLANTATION显示文摘 | ANTHONY M. D?ALESSANDRO MUNCI KALAYOGLU HANS W. SOLLINGER ROBERT M. HOFFMANN ALAN REED STUART J. KNECHTLE JOHN D. PIRSCH GHOLAM R. HAFEZ DAVID LORENTZEN FOLKERT O. BELZER | 1991 | Transplantation1991，，1： | 2 |
| 10 | Limited impact of IL28B genotype on response rates in telaprevir-treated patients with prior treatment failure显示文摘 | Stanislas Pol Jeroen Aerssens Stefan Zeuzem Pietro Andreone Eric J. Lawitz Stuart Roberts Zobair Younossi Graham R. Foster Roberto Focaccia Andrzej Horban Paul J. Pockros Rolf P.G. Van Heeswijk Sandra De Meyer Don Luo Martyn Botfield Maria Beumont Gaston | 2013 | Journal of Hepatology2013，，5： | 2 |
| 11 | Progression to chronic atrial fibrillation after the initial diagnosis of paroxysmal atrial fibrillation: Results from the Canadian Registry of Atrial Fibrillation显示文摘 | Charles R. Kerr Karin H. Humphries Mario Talajic George J. Klein Stuart J. Connolly Martin Green John Boone Robert Sheldon Paul Dorian David Newman | 2005 | American Heart Journal2005，，3： | 2 |
| 12 | 年龄相关性黄斑变性自我管理第6个月时的随访 一项随机对照试验显示文摘目的:通过测试情绪和功能以评估一项年龄相关性黄斑变性(AMD)的自我管理方案6个月时的有效性。该方案由健康教育和旨在提高生活质量的训练组成。方法:将252例患有进展性AMD的老年成人志愿者(平均年龄,80.8岁)中的214例随机分为3组,一组为12h自我管理方案(n=82),一组为12小时录像健康教育(n=66),一组为静态观察(n=66),分析6个月时随访的数据。主要结果测试是精神痛苦(美国情绪量表)。次要结果测试包括功能(国立眼科研究所视功能调查表),对日常生活中AMD挑战的自身把握能力(AMD自身效应调查表),以及运用精神障碍诊断及统计手册第4版检测抑郁情况。结果:在第6个月随访时,与对照组相比,自我管理组受试者的精神痛苦明显较小(P=0.008),功能更好(P=0.05);自身效应明显提高(P=0.006)。与非抑郁病例相比,在抑郁病例中迟发效应更为常见。最后,在第6个月随访时自我管理组的临床抑郁症发病率明显低于对照组(P=0.05)。结论:在第6个月随访时持续的积极效果证实,对于视力低下的老年AMD患者,AMD自我管理方案可以有效地减少痛苦和病残,提高自身效应,以及防止忧郁症的发生。 | Barbara L. Brody Anne-Catherine Roch-Levecq Ronald G. Thomas Robert M. Kaplan Stuart I. Brown 王历阳(译) 朱志忠(校) | 2005 | 美国医学会眼科杂志(中文版)2005，17，3： | 2 |
| 13 | Genetic and environmental control of fruit maturation,dry matter and firmness in apple(Malus×domestica Borkh.)显示文摘For any given genotype,the environment in which an apple is grown can influence the properties of the fruit considerably.While there has been extensive research on the mechanism of the genetic control of fruit quality traits,less effort has been made to investigate the way that these genetic mechanisms interact with the environment.To address this issue,we employed a large‘Royal Gala’בBraeburn’population of 572 seedlings replicated over sites in three climatically diverse apple-growing regions in New Zealand.Phenotyping for traits including fruit maturation timing,firmness and dry matter content was performed at each of these three sites for a single growing season(2011),and at two sites(Motueka and Hawke’s Bay)for two seasons(2009 and 2010).The phenotype data collected over 2 years at two sites enabled the detection of 190 quantitative trait loci(QTL)that controlled these traits regardless of year or growing location,as well as some chromosomal loci that influenced the traits in a single given environment or year.For those loci that were environmentally stable over three sites,there was an interdependency of fruit maturation date,dry matter content and storage potential within this population,with two regions on Linkage Groups(LGs)10 and 16 strongly contributing.If these loci were used in a marker-assisted selection programme to select for progeny bearing firmer fruit,this would have the unintentional consequence of selecting,high dry matter content,later maturing apples.In addition,a further 113 new QTLs with a smaller effect were identified,some of which were exhibited only in a single growing environment,demonstrating the underlying complexity of control of traits determining fruit quality,in addition to the need for being aware of environmental effects when developing new apple varieties. | David Chagne Daya Dayatilake Robert Diack Murray Oliver Hilary Ireland Amy Watson Susan E Gardiner Jason W Johnston Robert J Schaffer Stuart Tustin | 2014 | Horticulture Research2014，1，1： | 2 |
| 14 | Heterogeneity and the Voluntary Provision of Public Goods显示文摘 | Kenneth S. Chan Stuart Mestelman Robert Moir R. Andrew Muller | 1999 | Experimental Economics1999，，1： | 1 |
| 15 | The effect of a self‐etching primer on the continuous demineralization of dentin显示文摘 | Sofia S. A.Oliveira Sally J.Marshall StefanHabelitz Stuart A.Gansky Robert S.Wilson Grayson W.Marshall | 2004 | European Journal of Oral Sciences2004，，4： | 1 |
| 16 | <ce:link locator='fx1'/> Mechanisms of Field Cancerization in the Human Stomach: The Expansion and Spread of Mutated Gastric Stem Cells显示文摘 | Stuart A.C. McDonald Laura C. Greaves Lydia Gutierrez–Gonzalez Manuel Rodriguez–Justo Maesha Deheragoda Simon J. Leedham Robert W. Taylor Chung Yin Lee Sean L. Preston Matthew Lovell Toby Hunt George Elia Dahmane Oukrif Rebecca Harrison Marco R. Novelli I | 2008 | Gastroenterology2008，，2： | 1 |
| 17 | MCMC methods for functions:modifying old algorithms to make them faster显示文摘 | COTTER S L ROBERTS G O STUART A M | 2013 | Statistical Science2013，28，3： | 1 |
| 18 | The impact of macroalgae on mean and turbulent flow fields显示文摘In this paper,we attempt to quantify the mean and turbulent flow fields around live macroalgae within a tidal inlet in Norway.Two Laminaria digitata specimens 0.50 m apart were selected for detailed study and a profiling ADV was used to collect 45 velocity profiles,each composed of up to seven 0.035 m-high profiles collected for 240 s at 100 Hz,at a streamwise spacing of 0.25 m and cross-stream spacing of 0.20 m.To quantify the impact of the macroalgae,measurements were repeated over a sparser grid after the region had been completely cleared of algae and major roughness elements. | THOMAS Robert E. MCLELLAND Stuart J. | 2015 | Journal of Hydrodynamics2015，27，3： | 1 |
| 19 | Increased incidence of cancer and cancer-related mortality among persons with chronic hepatitis C infection, 2006–2010显示文摘 | Robert D. Allison Xin Tong Anne C. Moorman Kathleen N. Ly Loralee Rupp Fujie Xu Stuart C. Gordon Scott D. Holmberg | 2015 | Journal of Hepatology2015，，4： | 1 |
| 20 | Limited impact of IL28B genotype on response rates in telaprevir-treated patients with prior treatment failure显示文摘 | Stanislas Pol Jeroen Aerssens Stefan Zeuzem Pietro Andreone Eric J. Lawitz Stuart Roberts Zobair Younossi Graham R. Foster Roberto Focaccia Andrzej Horban Paul J. Pockros Rolf P.G. Van Heeswijk Sandra De Meyer Don Luo Martyn Botfield Maria Beumont Gaston | 2013 | Journal of Hepatology2013，，5： | 1 |
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