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| 1 | Black carbon aerosols and their radiative properties in the Pearl River Delta region显示文摘The climatic and environmental effects of atmospheric aerosols are a hot topic in global science community, and radiative properties of the aerosols are one of the important parameters in assessing climatic change. Here we studied the black carbon concentration and absorption coefficient measured with aethalometers, scattering coefficient measured with nephelometers, and single scattering albedo derived at an atmospheric composition watch station in Guangzhou from 2004 to 2007. Our main results are as follows. The data of black carbon concentration and absorption coefficients measured with instruments cannot be directly used until they are measured in parallel with internationally accepted instruments for comparison, calibration, and reduction. After evaluation of the data, the result shows that the monthly mean of BC concentration varies 3.1―14.8 μg·m-3 and the concentration decreases by about 1 μg·m-3 in average over the four years; It is higher in the dry season with a multi-year mean of 8.9 μg/m3 and lower in the rainy season with a multi-year mean of 8.0 μg·m-3; The extreme maximum of monthly mean concentration occurred in December 2004 and extreme minimum in July 2007, and a 4-year mean is 8.4 μg·m-3. It is also shown that monthly mean scattering coefficient derived varies 129 -565 Mm-1, monthly mean absorption coefficient 32-139 Mm-1, and monthly mean single scattering albedo 0.71-0.91, with annual mean values of 0.80, 0.82, 0.79 and 0.84 for 2004, 2005, 2006 and 2007, respectively. Three instruments were used to take simultaneous measurements of BC in PM10, PM2.5, and PM1 and the results showed that PM2.5 took up about 90% of PM10 and PM1 accounted for about 68% of PM2.5, and BC aerosols are mainly present in fine particulates. The variability of BC concentrations is quite consistent between the Nancun station (141 m above sea level) and the Panyu station (13 m above sea level), which are 8 km apart from each other. The concentration in higher altitude station (Panyu) is consistently lower than the lower altitude station (Nancun), and the difference of annual mean is about 4 μg·m-3. | WU Dui MAO JieTai DENG XueJiao TIE XueXi ZHANG YuanHang ZENG LiMin LI Fei TAN HaoBo BI XueYan HUANG XiaoYing CHEN Jing DENG Tao | 2009 | Science China Earth Sciences2009，52，8： | 58 |
| 2 | Tumor-secreted miR-214 induces regulatory T cells: a major link between immune evasion and tumor growth显示文摘 | Yuan Yin Xing Cai Xi Chen Hongwei Liang Yujing Zhang Jing Li Zuoyun Wang Xiulan Chen Wen Zhang Seiji Yokoyama Cheng Wang Liang Li Limin Li Dongxia Hou Lei Dong Tao Xu Takachika Hiroi Fuquan Yang Hongbin Ji Junfeng Zhang Ke Zen Chen-Yu Zhang | 2014 | Cell Research2014，24，10： | 33 |
| 3 | Human umbilical cord-derived mesenchymal stem cell therapy in patients with COVID-19:a phase 1 clinical trial显示文摘No effective drug treatments are available for coronavirus disease 2019(COVID-19).Host-directed therapies targeting the underlying aberrant immune responses leading to pulmonary tissue damage,death,or long-term functional disability in survivors require clinical evaluation.We performed a parallel assigned controlled,non-randomized,phase 1 clinical trial to evaluate the safety of human umbilical cord-derived mesenchymal stem cells(UC-MSCs)infusions in the treatment of patients with moderate and severe COVID-19 pulmonary disease.The study enrolled 18 hospitalized patients with COVID-19(n=9 for each group).The treatment group received three cycles of intravenous infusion of UC-MSCs(3×107 cells per infusion)on days 0,3,and 6.Both groups received standard COVID-treatment regimens.Adverse events,duration of clinical symptoms,laboratory parameters,length of hospitalization,serial chest computed tomography(CT)images,the PaO2/FiO2 ratio,dynamics of cytokines,and IgG and IgM anti-SARS-CoV-2 antibodies were analyzed.No serious UC-MSCs infusion-associated adverse events were observed.Two patients receiving UC-MSCs developed transient facial flushing and fever,and one patient developed transient hypoxia at 12 h post UC-MSCs transfusion.Mechanical ventilation was required in one patient in the treatment group compared with four in the control group.All patients recovered and were discharged.Our data show that intravenous UC-MSCs infusion in patients with moderate and severe COVID-19 is safe and well tolerated.Phase 2/3 randomized,controlled,double-blinded trials with long-term follow-up are needed to evaluate the therapeutic use of UC-MSCs to reduce deaths and improve long-term treatment outcomes in patients with serious COVID-19. | Fanping Meng Ruonan Xu Siyu Wang Zhe Xu Chao Zhang Yuanyuan Li Tao Yang Lei Shi Junliang Fu Tianjun Jiang Lei Huang Peng Zhao Xin Yuan Xing Fan Ji-Yuan Zhang Jinwen Song Dawei Zhang Yanmei Jiao Limin Liu Chunbao Zhou Markus Maeurer Alimuddin Zumla Ming Shi Fu-Sheng Wang | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 16 |
| 4 | Ni nanoparticles supported on carbon as efficient catalysts for the hydrolysis of ammonia borane显示文摘我们在在氨 borane (AB ) 的催化水解作用在碳(Ni/C ) 和他们的申请上支持的三种 Ni nanoparticles 的准备报导。三 Ni/C 催化剂从一个 Ni 金属器官的框架(Ni-MOF ) 被准备由有 KBH4 的减小的先锋,在 700 戠慥? 湥的锻烧吗? | Limin Zhou Tianran Zhang Zhanliang Tao Jun Chen | 2014 | Nano Research2014，7，5： | 13 |
| 5 | Pretreatment with Danhong injection protects the brain against ischemia-reperfusion injury显示文摘Danhong injection(DHI),a Chinese Materia Medica standardized product extracted from Radix Salviae miltiorrhizae and Flos Carthami tinctorii,is widely used in China for treating acute ischemic stroke.In the present study,we explored the neuroprotective efficacy of DHI in a rat model of temporary middle cerebral artery occlusion,and evaluated the potential mechanisms underlying its effects.Pretreatment with DHI(0.9 and 1.8 mL/kg)resulted in a significantly smaller infarct volume and better neurological scores than pretreatment with saline.Furthermore,DHI significantly reduced the permeability of the blood-brain barrier,increased occludin protein expression and decreased neutrophil infiltration,as well as profoundly suppressing the upregulation of matrix metallopeptidase-9 expression seen in rats that had received vehicle.Matrix metallopeptidase-2 expression was not affected by ischemia or DHI.Moreover,DHI(1.8 mL/kg)administered 3 hours after the onset of ischemia also improved neurological scores and reduced infarct size.Our results indicate that the neuroprotective efficacy of DHI in a rat model of cerebral ischemia-reperfusion injury is mediated by a protective effect on the blood-brain barrier and the reversal of neutrophil infiltration. | Shaoxia Wang Hong Guo Xumei Wang Lijuan Chai Limin Hu Tao Zhao Buchang Zhao Xiaoxu Tan Feifei Jia | 2014 | Neural Regeneration Research2014，9，15： | 12 |
| 6 | Classification of hyperspectral remote sensing images using frequency spectrum similarity显示文摘An algorithm of hyperspectral remote sensing images classification is proposed based on the frequency spectrum of spectral signature.The spectral signature of each pixel in the hyperspectral image is taken as a discrete signal,and the frequency spectrum is obtained using discrete Fourier transform.The discrepancy of frequency spectrum between ground objects' spectral signatures is visible,thus the difference between frequency spectra of reference and target spectral signature is used to measure the spectral similarity.Canberra distance is introduced to increase the contribution from higher frequency components.Then,the number of harmonics involved in the proposed algorithm is determined after analyzing the frequency spectrum energy cumulative distribution function of ground object.In order to evaluate the performance of the proposed algorithm,two hyperspectral remote sensing images are adopted as experimental data.The proposed algorithm is compared with spectral angle mapper (SAM),spectral information divergence (SID) and Euclidean distance (ED) using the product accuracy,user accuracy,overall accuracy,average accuracy and Kappa coefficient.The results show that the proposed algorithm can be applied to hyperspectral image classification effectively. | WANG Ke GU XingFa YU Tao MENG QingYan ZHAO LiMin FENG Li | 2013 | Science China(Technological Sciences)2013，56，4： | 10 |
| 7 | Multilayered electret films based triboelectric nanogenerator显示文摘摩擦电 nanogenerator (TENG ) 是基于薄电影的表面接触充电把周围的机械精力变换成电的一台简单、合算的设备。有限表面费用密度可以影响 TENG 的全面表演。在这份报纸,基于的 TENG (E-TENG ) 由日冕制作了收费的一部新奇驻极体电影被建议那极大地作为与使遭到联系充电的那些相比提高薄电影的有效表面费用密度。E-TENG 的电线走火电流,转移电的费用密度,和开电路的电压被调查了,用控告电压,针尖距离和时间以便探索最佳的不同日冕试验性的条件。E-TENG 的电线走火电流,转移电的费用密度,和开电路的电压比那些平常的 polytetrafluoroethylene (PTFE ) 拍摄基于的 TENG 的被发现是大约七大倍。基于日冕收费,几 multilayered E-TENGs 被制作了,并且有层的不同数字的 E-TENGs 的电线走火电流,转移电的费用密度,和开电路的电压为完成最佳的表演被学习。这个工作为改进有效表面费用密度并且从而增加 TENG 的输出能力提供一条有效途径,它将极大地在自我动力的便携式的电子学和传感器网络支持 TENG 应用程序。 | Tao Zhou Limin Zhang Fei Xue Wei Tang Chi Zhang Zhong Lin wang | 2016 | Nano Research2016，9，5： | 10 |
| 8 | Enhancement of High Energy Electron Fluxes and Variation of Atmospheric Electric Field in the Antarctic Region显示文摘High-energy electron precipitation in the high latitude regions enhances the ionization of the atmosphere,and subsequently increases the atmospheric conductivities and the vertical electric field of the atmosphere near the ground as well.The High-Energy Electron Flux(HEEF) data measured by the Fengyun-3 meteorological satellite are analyzed together with the data of nearsurface atmospheric vertical electric field measured at the Russian Vostok Station.Three HEEF enhancements are identified and it is shown that when the HEEF increases to a certain level,the local atmospheric vertical electric field near the ground can increase substantially than usual.The response time of the electric field to HEEF enhancement is about 3.7 to 4 days. | LI Renkang CHEN Tao LUO Jing ZHOU Limin HE Zhaohai WANG Chunqin SUN Yueqiang | 2016 | 空间科学学报2016，36，1： | 8 |
| 9 | Corrosion behavior of a CuCrNiAl alloy in the presence of NaCl deposit显示文摘The corrosion behavior of a CuCrNiAl alloy with NaCl deposit at 700 and 900oC was studied by means of met-alloscope, XRD, SEM/EDX, and thermogravimetric analysis. The results indicated that the corrosion of the CuCrNiAl alloy beneath the NaCl deposit is severe; the corrosion production is loose and easy to scale off; the Cr phase is easier to erode than the Cu phase, and the contents of Cu and Cr decrease when the content of Ni increases in the matrix of the alloy be-neath the corrosion region. The effects of distortion on the corrosion of the CuCrNiAl alloy were discussed, and the accel-eration mechanisms of NaCl on the corrosion were also discussed. | XU Tao CHANG Limin LIU Jianhua | 2006 | Rare Metals2006，25，3： | 6 |
| 10 | Uncommon EGFR mutations in a cohort of Chinese NSCLC patients and outcomes of first-line EGFR-TKIs and platinum-based chemotherapy显示文摘Objective: Data on the clinical activity of epidermal growth factor receptor(EGFR) tyrosine kinase inhibitors(TKIs) in patients with non-small-cell lung cancer(NSCLC) and uncommon EGFR mutations remain insufficient.This study aimed to investigate the effect of first-line EGFR-TKIs or platinum-based chemotherapy in NSCLC patients with uncommon EGFR mutations.Methods: We retrospectively enrolled 504 patients with EGFR-mutant NSCLC.The clinical characteristics and treatment outcomes were collected and compared between patients with common and uncommon EGFR-mutant NSCLC.Results: Seventy patients(13.9%) harboring uncommon EGFR mutations were included.Thirty of these patients received EGFR-TKIs and 40 received platinum-based chemotherapy as first-line therapy.The objective response rate(ORR) and median progression-free survival(m PFS) of patients treated with TKIs in the uncommon mutation group was significantly inferior to that in the common mutation group(ORR: 23.3% vs.51.8%,P=0.003; m PFS:7.1 vs.10.9 months,P<0.001).In the uncommon group,m PFS was similar between first-line EGFR-TKIs treatment and platinum-based chemotherapy(7.1 vs.6.1 months,P=0.893).In patients with EGFR G719 X or L861 Q mutations,the m PFS was longer in the first-line EGFR-TKIs treatment group than in the chemotherapy group,but the difference was not statistically significant(G719 X: 8.2 vs.5.8 months,P=0.061; L861 Q: 7.6 vs.4.1 months,P=0.872).Multivariate analyses identified adenocarcinoma(P=0.003) as the independent predictive factor for PFS in patients with uncommon EGFR mutations who were treated with first-line EGFR-TKIs.Conclusions: The current study demonstrated that the effect of first-line EGFR-TKIs was similar to that of platinum-based chemotherapy in patients with uncommon EGFR-mutant NSCLC.Adenocarcinoma was the independent predictive factor for PFS in uncommon EGFR-mutant NSCLC patients treated with first-line EGFRTKIs. | Jinpeng Shi Hui Yang Tao Jiang Xuefei Li Chao Zhao Limin Zhang Sha Zhao Xiaozhen Liu Yijun Jia Yan Wang Lei Xi Shijia Zhang Chunxia Su Shengxiang Ren Caicun Zhou | 2017 | Chinese Journal of Cancer Research2017，29，6： | 6 |
| 11 | Optical Micro/Nano Fibers Enabled Smart Textiles for Human-Machine Interface显示文摘Wearable human-machine interface(HMI)is an advanced technology that has a wide range of applications from robotics to augmented/virtual reality(AR/VR).In this study,an optically driven wearable human-interactive smart textile is proposed by integrating a polydimethylsiloxane(PDMS)patch embedded with optical micro/nanofibers(MNF)array with a piece of textiles.Enabled by the highly sensitive pressure dependent bending loss of MNF,the smart textile shows high sensitivity(65.5 kPa^(−1))and fast response(25 ms)for touch sensing.Benefiting from the warp and weft structure of the textile,the optical smart textile can feel slight finger slip along the MNF.Furthermore,machine learning is utilized to classify the touch manners,achieving a recognition accuracy as high as 98.1%.As a proof-of-concept,a remote-control robotic hand and a smart interactive doll are demonstrated based on the optical smart textile.This optical smart textile represents an ideal HMI for AR/VR and robotics applications. | Shuqi Ma Xiaoyu Wang Pan Li Ni Yao Jianliang Xiao Haitao Liu Zhang Zhang Longteng Yu Guangming Tao Xiong Li Limin Tong Lei Zhang | 2022 | Advanced Fiber Materials2022，4，5： | 5 |
| 12 | Wideband Signal Detection Based on MWC Discrete Compressed Sampling Structure显示文摘In order to solve the cross-channel signal problem caused by the uniform channelized wideband digital receiver when processing wideband signal and the problem that the sensitivity of the system greatly decreases when the bandwidth of wideband digital receiver increases,which both decrease the wideband radar signal detection performance,a new wideband digital receiver based on the modulated wideband converter(MWC)discrete compressed sampling structure and an energy detection method based on the new receiver are proposed.Firstly,the proposed receiver utilizes periodic pseudo-random sequences to mix wideband signals with baseband and other sub-bands.Then the mixed signals are low-pass filtered and downsampled to obtain the baseband compressed sampling data,which can increase the sensitivity of the system.Meanwhile,the cross-channel signal will all appear in any subbands,so the cross-channel signal problem can be solved easily by processing the baseband compressed sampling data.Secondly,we establish the signal detection model and formulate the criterion of the energy detection method.And we directly utilize the baseband compressed sampling data to carry out signal detection without signal reconstruction,which decreases the complexity of the algorithm and reduces the computational burden.Finally,simulation experiments demonstrate the effectiveness of the proposed receiver and show that the proposed signal detection method is effective in low signal-to-noise ratio(SNR)compared with the conventional energy detection and the probability of detection increases significantly when SNR increases. | Chen Tao Liu Lizhi Guo Limin | 2017 | Transactions of Nanjing University of Aeronautics and Astronautics2017，34，2： | 4 |
| 13 | Optimizing energy harvesting performance by tailoring ferroelectric/relaxor behavior in KNN-based piezoceramics显示文摘Piezoelectric energy harvesters(PEHs)fabricated using piezoceramics could convert directly the mechanical vibration energy in the environment into electrical energy.The high piezoelectric charge coefficient(d_(33))and large piezoelectric voltage coefficient(g_(33))are key factors for the high-performance PEHs.However,high d_(33)and large g_(33)are difficult to simultaneously achieve with respect to g_(33)=d_(33)/(e_(0)e_(r))and d_(33)=2Qe_(0)e_(r)P_(r).Herein,the energy harvesting performance is optimized by tailoring the CaZrO_(3)content in(0.964−x)(K_(0.52)Na_(0.48))(Nb_(0.96)Sb_(0.04))O_(3)-0.036(Bi_(0.5)Na_(0.5))ZrO_(3)-xCaZrO_(3)ceramics.First,the doping CaZrO_(3)could enhance the dielectric relaxation due to the compositional fluctuation and structural disordering,and thus reduce the domain size to~30 nm for x=0.006 sample.The nanodomains switch easily to external electric field,resulting in large polarization.Second,the rhombohedral-orthorhombic-tetragonal phases coexist in x=0.006 sample,which reduces the polarization anisotropy and thus improves the piezoelectric properties.The multiphase coexistence structures and miniaturized domains contribute to the excellent piezoelectric properties of d_(33)(354 pC/N).Furthermore,the dielectric relative permittivity(ε_(r))reduces monotonously as the CaZrO_(3)content increases due to the relatively low ion polarizability of Ca^(2+)and Zr^(4+).As a result,the optimized energy conversion coefficient(d_(33)×g_(33),5508×10^(−15)m^(2)/N)is achieved for x=0.006 sample.Most importantly,the assembled PEH with the optimal specimen shows the excellent output power(~48 mW)and lights up 45 red commercial light-emitting diodes(LEDs).This work demonstrates that tailoring ferroelectric/relaxor behavior in(K,Na)NbO_(3)-based piezoelectric ceramics could effectively enhance the electrical output of PEHs. | Yu HUAN Xinjian WANG Wenyu YANG Limin HOU Mupeng ZHENG Tao WEI Xiaohui WANG | 2022 | Journal of Advanced Ceramics2022，11，6： | 3 |
| 14 | The influence of surface roughness and deformation on dechromization of a Cu-Cr alloy显示文摘In order to realize the dechromization of a Cu-Cr alloy in HCl solution, the influence of surface roughness and deformation on dechromization of the Cu-Cr alloy was studied by means of metallographic observation, TEM, SEM/EDX, and CH1660A electrochemical instrument. The results showed that the bigger the sample’s deformation and surface rough- ness, the shorter the incubation time of dechromization of the Cu-Cr alloy, and the trend of dechromization increases. Simultaneously, the deformation can increase the dechromization rate, invite stress corrosion, and decrease the compactibility of the microstructure of the dechromization layer. And yet the surface roughness does not obviously affect the dechromization rate and the compactibility of the dechromization layer. | YU Cuiyan LIU Jianhua ZHOU Limin XU Tao | 2006 | Rare Metals2006，25，2： | 3 |
| 15 | Identification of miRNomes in Human Liver and Hepatocellular Carcinoma Reveals miR-199a/b-3p as Therapeutic Target for Hepatocellular Carcinoma显示文摘 | Jin Hou Li Lin Weiping Zhou Zhengxin Wang Guoshan Ding Qiongzhu Dong Lunxiu Qin Xiaobing Wu Yuanyuan Zheng Yun Yang Wei Tian Qian Zhang Chunmei Wang Qinghua Zhang Shi-Mei Zhuang Limin Zheng Anmin Liang Wenzhao Tao Xuetao Cao | 2011 | Cancer Cell2011，，2： | 3 |
| 16 | Temperature dependence of niobium superconducting nanowire single-photon detectors in He-3 cryocooler显示文摘Performances of superconducting nanowire single-photon detectors(SNSPDs) based on low TCmaterials strongly depend on the operating temperatures. We have fabricated infrared-sensitive niobium SNSPDs based on doped niobium(Nb*) films and measured them in He-3cryocooler. The critical current approaches to the de-pairing current at 0.3 K. Therefore, with the decrease in temperatures, we have observed a monotonous increase of count rate at the wavelength of 1,521 nm and exponential decrease of dark count rate at all bias currents. The possible origin of dark counts for doped Nb devices is also discussed. | Tao Jia Chao Wan Limin Zhao Yu Zhou Qingyuan Zhao Min Gu Xiaoqing Jia Labao Zhang Biaobing Jin Jian Chen Lin Kang | 2014 | Chinese Science Bulletin2014，59，28： | 2 |
| 17 | Communication-Based Attacks Detection in Android Applications显示文摘The Android operating system provides a rich Inter-Component Communication(ICC) method that brings enormous convenience. However, the Android ICC also increases security risks. To address this problem, a formal method is proposed to model and detect inter-component communication behavior in Android applications. Firstly,we generate data flow graphs and data facts for each component through component-level data flow analysis.Secondly, our approach treats ICC just like method calls. After analyzing the fields and data dependencies of the intent, we identify the ICC caller and callee, track the data flow between them, and construct the ICC model. Thirdly,the behavior model of Android applications is constructed by a formal mapping method for component data flow graph based on Pi calculus. The runtime sensitive path trigger detection algorithm is then given. Communicationbased attacks are detected by analyzing intent abnormity. Finally, we analyze the modeling and detection efficiency,and compare it with relevant methods. Analysis of 57 real-world applications partly verifies the effectiveness of the proposed method. | Chuan Ma Tao Wang Limin Shen Dongkui Liang Shuping Chen Dianlong You | 2019 | Tsinghua Science and Technology2019，24，5： | 2 |
| 18 | Secreted Monocytic miR-150 Enhances Targeted Endothelial Cell Migration显示文摘 | Yujing Zhang Danqing Liu Xi Chen Jing Li Limin Li Zhen Bian Fei Sun Jiuwei Lu Yuan Yin Xing Cai Qi Sun Kehui Wang Yi Ba Qiang Wang Dongjin Wang Junwei Yang Pingsheng Liu Tao Xu Qiao Yan Junfeng Zhang Ke Zen Chen-Yu Zhang | 2010 | Molecular Cell2010，，1： | 2 |
| 19 | Modeling diurnal variation of ground thermal radiance images using energy balance model and endmember composing technique显示文摘Modeling and analyzing dynamic changes of land thermal radiance scenes play an important role in thermal remote sensing.In this paper,the diurnal variation of ground surface thermal scene is mainly discussed.Firstly,based on the land surface energy balance equation,the diurnal variation of land surface temperatures(LSTs) over bare land covers were simulated by an analytical thermal model with second harmonic terms,and the diurnal LST variation of vegetation canopy was simulated using the Cupid model.Secondly,normalized difference vegetation index(NDVI),normalized difference water index(NDWI),and ratio resident-area index(RRI) were used to evaluate the endmember abundance of four land cover types including vegetation,bare soil,impervious and water area,which were calculated from IKONOS visible and near infrared(VNIR) bands.Finally,the thermal radiance scenes at various times and view angles were modeled based on the linear-energy-mixing hypothesis.The results showed that the simulated daily LST variations for vegetated and bare surfaces are correlated with the measured values with a maximum standard deviation of 2.7°C,that land thermal radiant textures with high-resolution are restored from the linear-energy-mixing method,and that the information abundance of the scene are related to the distribution of land cover,the imaging time,and the view angle. | ZHAO LiMin GU XingFa YU Tao WAN Wei XIONG Pan XIE YanHua ZHANG Lun | 2012 | Science China(Technological Sciences)2012，55，11： | 2 |
| 20 | Secreted Monocytic miR-150 Enhances Targeted Endothelial Cell Migration显示文摘 | Yujing Zhang Danqing Liu Xi Chen Jing Li Limin Li Zhen Bian Fei Sun Jiuwei Lu Yuan Yin Xing Cai Qi Sun Kehui Wang Yi Ba Qiang Wang Dongjin Wang Junwei Yang Pingsheng Liu Tao Xu Qiao Yan Junfeng Zhang Ke Zen Chen-Yu Zhang | 2010 | Molecular Cell2010，，1： | 1 |
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