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| 1 | Isolation of a Novel Lodging Resistance QTL Gene Involved in Strigolactone Signaling and Its Pyramiding with a QTL Gene Involved in Another Mechanism显示文摘住宿是到达到增加的庄稼生产率的一个主要障碍。在一次尝试到在米饭为灰煤杆力量理解机制,我们孤立一个有效量的特点地点( QTL ),强壮的 CULM3 ( SCM3 ),哪个与米饭 TEOSINTE BRANCHED1 ( OsTB1 )相同的原因的基因,基因以前报导了断然控制发信号的 strigolactone ( SL )。带 SCM3 的一根 near-isogenic 线(无) 证明尽管有期望的减少,提高的灰煤杆力量和增加的小穗状花小穗在 tiller 数字数,显示 SL 也有在提高灰煤杆力量和小穗状花小穗数字的一个积极角色。我们生产了带 SCM3 和 SCM2 的一根节节上升的线,编码涉及圆锥花序开发的 APO1 的另一 QTL。NIL-SCM2+SCM3 比 NIL-SCM2 和 NIL-SCM3 和这些 QTL 的添加剂效果引起的一个增加的小穗状花小穗数字显示出强壮得多的灰煤杆。我们讨论没有为繁殖导致有害特点,利用这些强壮的灰煤杆 QTL 的合适的等位基因的重要性。 | Kenji Yano Taiichiro Ookawa Koichiro Aya Yusuke Ochiai Tadashi Hirasawa Takeshi Ebitani Takeshi Takarada Masahiro Yano Toshio Yamamoto Shuichi Fukuoka Jianzhong Wu Tsuyu Ando Reynante Lacsamana Ordonio Ko Hirano Makoto Matsuoka | 2015 | Molecular Plant2015，8，2： | 12 |
| 2 | Population Genomic Analysis and De Novo Assembly Reveal the Origin of Weedy Rice as an Evolutionary Game显示文摘Crop weediness,especially that of weedy rice(Oryza sativa f.spontanea),remains mysterious.Weedy rice possesses robust ecological adaptability;however,how this strain originated and gradually formed proprietary genetic features remains unclear?Here,we demonstrate that weedy rice at Asian high latitudes(WRAH)is phylogenetically well defined and possesses unselected genomic characteristics in many divergence regions between weedy and cultivated rice.We also identified novel quantitative trait loci underlying weedy-specific traits,and revealed that a genome block on the end of chromosome 1 is associated with rice weediness.To identify the genomic modifications underlying weedy rice evolution,we generated the first de novo assembly of a high-quality weedy rice genome(WR04-6),and conducted a comparative genomics study between WR04-6 with other rice reference genomes.Multiple lines of evidence,including the results of demographic scenario comparisons,suggest that differentiation between weedy rice and cultivated rice was initiated by genetic improvement of cultivated rice and that the essence of weediness arose through semi-domestication.A plant height model further implied that the origin of WRAH can be modeled as an evolutionary game and indicated that strategy-based selection driven by fitness shaped its genomic diversity. | Jian Sun Dianrong Ma Liang Tang Minghui Zhao Guangchen Zhangh Wenjia Wang Jiayu Song Xiang Li Zimeng Liu Wenxing Zhang Quan Xu Yuncheng Zhou Jianzhong Wu Toshio Yamamoto Fei Dai Yan Lei Song Li Gang Zhou Hongkun Zheng Zhengjin Xu Wenfu Chen | 2019 | Molecular Plant2019，12，5： | 9 |
| 3 | CO_2 insufflation for potentially diffi cult colonoscopies: Effi cacy when used by less experienced colonoscopists显示文摘AIM: To clarify the effectiveness of CO2 insufflation in potentially difficult colonoscopy cases, particularly in relation to the experience level of colonoscopists.METHODS: One hundred twenty potentially difficult cases were included in this study, which involved females with a low body mass index and patients with earlier abdominal and/or pelvic open surgery or previously diagnosed left-side colon diverticulosis. Patients receiving colonoscopy examinations without sedation using a pediatric variable-stiffness colonoscope were divided into two groups based on either CO2 or standard air insufflation. Both insufflation procedures were also evaluated according to the experience level of the respective colonoscopists who were divided into an experienced colonoscopist (EC) group and a less experienced colonoscopist (LEC) group. Study measurements included a 100-mm visual analogue scale (VAS) for patient pain during and after colonoscopyexaminations, in addition to insertion to the cecum and withdrawal times.RESULTS: Examination times did not differ, however, VAS scores in the CO2 group were signifi cantly better than in the air group (P < 0.001, two-way ANOVA) from immediately after the procedure and up to 2 h later. There were no significant differences between either insufflation method in the EC group (P = 0.29), however, VAS scores for CO2 insufflation were significantly better than air insufflation in the LEC group (P = 0.023) immediately after colonoscopies and up to 4 h afterwards.CONCLUSION: CO2 insufflation reduced patient pain after colonoscopy in potentially difficult cases when performed by LECs. | Toshio Uraoka Jun Kato Motoaki Kuriyama Keisuke Hori Shin Ishikawa Keita Harada Koji Takemoto Sakiko Hiraoka Hideyuki Fujita Joichiro Horii Yutaka Saito Kazuhide Yamamoto | 2009 | World Journal of Gastroenterology2009，15，41： | 5 |
| 4 | Exploitation of shape memory alloy actuator using resistance feedback control and its development | Hiroki CHO Takaei YAMAMOTO Yuji TAKEDA Akihiko SUZUKI Toshio SAKUMA | 2010 | Progress in Natural Science:Materials International2010，20，1： | 3 |
| 5 | iTRAQ-Based Proteomics Investigation of Critical Response Proteins in Embryo and Coleoptile During Rice Anaerobic Germination显示文摘Direct-seeding of rice has become popular in recent years due to its low cost and convenience,however,hypoxic condition limits seedling establishment.In this study,weedy rice WR04-6 with high germination ability under anaerobic conditions was used as a gene donor,and we successfully improved the seedling establishment rate of rice cultivar Qishanzhan(QSZ)based on selection of a new rice line R42 from the recombinant inbred line population.R42 inherited high anaerobic germination(AG)ability,and was used for isobaric tags for relative and absolute quantitation(iTRAQ)-based comparative proteomic studies with QSZ to further explore the molecular mechanism of AG.A total of 719 differentially abundant proteins(DAPs)were shared by R42 and QSZ responded to AG,and thus defined as common response DAPs.A total of 300 DAPs that responded to AG were only identified from R42,which were defined as tolerance-specific DAPs.The common response and tolerance-specific DAPs had similar biochemical reaction processes and metabolic pathways in response to anoxic stress,however,they involved different proteins.The tolerance-specific DAPs were involved in amino acid metabolism,starch and sucrose metabolism,tricarboxylic acid cycle pathway,ethylene synthesis pathway,cell wall-associated proteins and activity of active oxygen scavenging enzyme.The in silico protein-protein interactions for the top 60 DAPs indicated that tolerance-specific DAPs had relatively independent protein interaction networks in response to an anoxic environment compared with common response DAPs.The results of physiological indicators showed thatα-amylase and superoxide dismutase activities of R42 were significantly increased under anoxic conditions compared with aerobic conditions.Multiple lines of evidence from western blot,physiological analysis and quantitatDirect seeding of rice has become popular in recent years due to its low cost and convenience,however,hypoxic conditions can limit seedling establishment.In the present study,weedy rice WR04-6 with high germination ability in anaerobic conditions was used as the gene donor and successfully improved the seedling establishment rate of rice cultivar Qishanzhan(QSZ)based on selection of a new rice line R42 from the recombinant inbred line(RIL)population.R42 inherited the had high anaerobic germination(AG)ability,which was used for the isobaric tags for relative and absolute quantitation(iTRAQ)based comparative proteomic studies with QSZ to further explore the molecular mechanism of AG.A total of 719 differentially abundant proteins(DAPs)shared by R42 and QSZ responded to AG and were thus defined as common response DAPs.A total of 300 DAPs that responded to AG were only identified from R42,which were defined as tolerance-specific DAPs.The common response and tolerance-specific DAPs had similar biochemical reaction processes and metabolic pathways in response to anoxic stress,however they involved different proteins.The 300 tolerance-specific DAPs were involved in amino acid metabolism,starch and sucrose metabolism,TCA cycle pathways,ethylene synthesis pathway,cell wall-associated proteins and activity of active oxygen scavenging enzyme.The in silico protein-protein interactions for the top 60 DAPs indicated that tolerance-specific DAPs had relatively independent protein interaction networks in response to an anoxic environment compared with common response DAPs.The results of physiological indicators showed thatα-amylase and SOD activities of R42 were significantly increased under anoxic conditions compared with aerobic conditions.Multiple lines of evidence from western blot,physiological analyses and real-time PCR jointly supported the reliability of proteomics data.In summary,our findings deepened the understanding of the molecular mechanism for the rice response to AG.ive real-time PCR jointly supported the reliability of proteomics data.In summary,our findings deepened the understanding of the molecular mechanism for the rice response to AG. | Zhang Guangchen Liu Zimeng Liu Yoxihong Kuya Noriyuki HuAYuchen Shi Hongru Zhao Weilin Han Yuqing Yamamoto Toshio Chen Wenfu Sun Jian | 2021 | Rice science2021，28，4： | 2 |
| 6 | A Novel Approach to the Prevention of Postoperative Delirium in the Elderly After Gastrointestinal Surgery显示文摘 | Ken-ichiro Aizawa Toshio Kanai Yoshiro Saikawa Tsukasa Takabayashi Yukio Kawano Naoto Miyazawa Tetsuya Yamamoto | 2002 | Surgery Today2002，，4： | 2 |
| 7 | Guidelines for the management of biliary tract and ampullary carcinomas: surgical treatment显示文摘 | Satoshi Kondo Tadahiro Takada Masaru Miyazaki Shuichi Miyakawa Kazuhiro Tsukada Masato Nagino Junji Furuse Hiroya Saito Toshio Tsuyuguchi Masakazu Yamamoto Masato Kayahara Fumio Kimura Hideyuki Yoshitomi Satoshi Nozawa Masahiro Yoshida Keita Wada Satoshi | 2008 | Journal of Hepato - Biliary - Pancreatic Surgery2008，，1： | 2 |
| 8 | Canopy temperature on clear and cloudy days can be used to estimate var-ietal differences in stomatal conductance in rice显示文摘 | TOSHIYUKI TAKAI MASAHIRO YANO TOSHIO YAMAMOTO | 2010 | Field Crops Research2010，115，： | 1 |
| 9 | Carcinoma of the colon in children: Case report and review of the Japanese literature显示文摘 | Kouta Yamamoto Toshio Tanaka Kenji Kuno Yasuo Amoh Yoshiro Takahashi Hayao Murakami | 1994 | Journal of Gastroenterology1994，，5： | 1 |
| 10 | Q-TARO: QTL Annotation Rice Online Database显示文摘 | Jun-ichi Yonemaru Toshio Yamamoto Shuichi Fukuoka Yusaku Uga Kiyosumi Hori Masahiro Yano | 2010 | Rice . 2010 (2-3)2010，，2： | 1 |
| 11 | Fine genetic mapping of the nuclear gene, Rf-1, that restores the BT-type cytoplasmic male sterility in rice (Oryza sativa L.) by PCR-based markers显示文摘 | Toshiyuki Komori Toshio Yamamoto Naoki Takemori Masakazu Kashihara Hideko Matsushima Naoto Nitta | 2003 | Euphytica2003，，2： | 1 |
| 12 | A novel adenovirus expressing human 4–1BB ligand enhances antitumor immunity显示文摘 | Hiroshi Yoshida Yu Katayose Michiaki Unno Masanori Suzuki Hideaki Kodama Shin-ichi Takemura Ryutaro Asano Hiroki Hayashi Kuniharu Yamamoto Seiki Matsuno Toshio Kudo | 2003 | Cancer Immunology Immunotherapy2003，，2： | 1 |
| 13 | Phase II study on the combination of irinotecan plus cisplatin as asecond?line therapy in patients with advanced or recurrent gastric cancer显示文摘 | Yasushi Rino Norio Yukawa Tsutomu Sato Takashi Oshima Hiroyasu Tanabe Yuji Yamamoto Hiroshi Matsukawa Ryuji Shiraishi Toshio Imada Munetaka Masuda | 2013 | Molecular and Clinical Oncology2013，，4： | 1 |
| 14 | Impact of body mass index and visceral adiposity on outcomes in colorectal cancer显示文摘 | Naoto YAMAMOTO Shoichi FUJII Tsutomu SATO Takashi OSHIMA Yasushi RINO Chikara KUNISAKI Munetaka MASUDA Toshio IMADA | 2012 | Asia‐Pacific Journal of Clinical Oncology2012，，4： | 1 |
| 15 | Properties of rice starch prepared by alkali method with various conditions显示文摘 | Yamamoto K Sumie S Toshio O | 1973 | Denpun Kagaku1973，20，： | 1 |
| 16 | Clinical evaluation of plasma des-γ-carboxy prothrombin as a marker protein of hepatocellular carcinoma in patients with tumors of various sizes显示文摘 | Dr. Akinori Kasahara MD Norio Hayashi MD Hideyuki Fusamoto MD Yoshio Kawada MD Yasukiyo Imai MD Hideo Yamamoto MD Eijiro Hayashi MD Toshio Ogihara MD Takenobu Kamada MD | 1993 | Digestive Diseases and Sciences1993，，12： | 1 |
| 17 | Predictive factors for technically difficult endoscopic submucosal dissection in the colorectum显示文摘 | Keisuke Hori Toshio Uraoka Keita Harada Reiji Higashi Yoshiro Kawahara Hiroyuki Okada Hemchand Ramberan Naohisa Yahagi Kazuhide Yamamoto | 2014 | Endoscopy2014，，10： | 1 |
| 18 | Anti-apoptotic and anti-senescence effects of Klotho on vascular endothelial cells显示文摘 | Masashi Ikushima Hiromi Rakugi Kazuhiko Ishikawa Yoshihiro Maekawa Koichi Yamamoto Junsuke Ohta Yukana Chihara Iwao Kida Toshio Ogihara | 2005 | Biochemical and Biophysical Research Communications2005，，3： | 1 |
| 19 | Properties of rice starch prepared by alkali method with various conditions显示文摘 | YAMAMOTO K SUMIE S TOSHIO O | 1973 | Denpun Kagaku1973，20，： | 1 |
| 20 | Gastric Emptying After Pylorus-Preserving Gastrectomy in Comparison with Conventional Subtotal Gastrectomy for Early Gastric Carcinoma显示文摘 | Toshio Imada Yasushi Rino Makoto Takahashi Shinsuke Hatori Jyun-ichi Tanaka Manabu Shiozawa Chao Chin Yuji Yamamoto Tomishige Amano Kazuo Nakamura | 1998 | Surgery Today1998，，2： | 1 |
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