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| 1 | Removal characteristics of microplastics by Fe-based coagulants during drinking water treatment显示文摘Microplastics have caused great concern worldwide recently due to their ubiquitous presence within the marine environment. Up to now, most attention has been paid to their sources,distributions, measurement methods, and especially their eco-toxicological effects. With microplastics being increasingly detected in freshwater, it is urgently necessary to evaluate their behaviors during coagulation and ultrafiltration(UF) processes. Herein, the removal behavior of polyethylene(PE), which is easily suspended in water and is the main component of microplastics, was investigated with commonly used Fe-based salts. Results showed that although higher removal efficiency was induced for smaller PE particles, low PE removal efficiency(below 15%) was observed using the traditional coagulation process, and was little influenced by water characteristics. In comparison to solution pH, PAM addition played a more important role in increasing the removal efficiency, especially anionic PAM at high dosage(with efficiency up to 90.9%). The main reason was ascribed to the dense floc formation and high adsorption ability because of the positively charged Fe-based flocs under neutral conditions. For ultrafiltration, although PE particles could be completely rejected,slight membrane fouling was caused owing to their large particle size. The membrane flux decreased after coagulation; however, the membrane fouling was less severe than that induced by flocs alone due to the heterogeneous nature of the cake layer caused by PE, even at high dosages of Fe-based salts. Based on the behavior exhibited during coagulation and ultrafiltration, we believe these findings will have potential application in drinking water treatment. | Baiwen Ma Wenjing Xue Yanyan Ding Chengzhi Hu Huijuan Liu Jiuhui Qu | 2019 | Journal of Environmental Sciences2019，31，4： | 29 |
| 2 | Human rhinovirus C infection is associated with asthma in children determined by x TAG respiratory viral panel FAST显示文摘Dear Editor,Cumulative evidence supports the role of early-life viral infections,especially respiratory syncytial virus(RSV)and human rhinovirus(HRV),as major antecedents of childhood asthma(Lemanske,2002;Jackson et al.,2008).In this study,the x TAG respiratory viral panel FAST(RVP FAST)assay,a multiplex polymerase chain reaction(PCR)-based method(Arens et al.,2010;BaladaLlasat et al.,2011;Gharabaghi et al.,2011;Selvaraju,2012),was used to investigate the association of infec- | Dongmei Chen Qinwei Song Runan Zhu Yuan Qian Yu Sun Jie Deng Fang Wang Yaxin Ding Run Tian Chuanhe Liu Wenjing Zhu Linqing Zhao | 2017 | Virologica Sinica2017，32，2： | 5 |
| 3 | Mars Ion and Neutral Particle Analyzer (MINPA) for Chinese Mars Exploration Mission (Tianwen-1): Design and ground calibration显示文摘The main objective of the Mars Ion and Neutral Particle Analyzer(MINPA)aboard the Chinese Mars Exploration Mission(Tianwen-1)is to study the solar wind-Mars interaction by measuring the ions and energetic neutral atoms(ENAs)near Mars.The MINPA integrates ion and ENA measurements into one sensor head,sharing the same electronics box.The MINPA utilizes a standard toroidal top-hat electrostatic analyzer(ESA)followed by a time of flight(TOF)unit to provide measurement of ions with energies from 2.8 eV to 25.9 keV and ENAs from 50 eV to 3 keV with a base time resolution of 4 seconds.Highly polished silicon single crystal substrates with an Al2O3 film coating are used to ionize the ENAs into positive ions.These ions can then be analyzed by the ESA and TOF,to determine the energy and masses of the ENAs.The MINPA provides a 360°×90°field of view(FOV)with 22.5°×5.4°angular resolution for ion measurement,and a 360°×9.7°FOV with 22.5°×9.7°angular resolution for ENA measurement.The TOF unit combines a-15 kV acceleration high voltage with ultra-thin carbon foils to resolve H+,He2+,He+,O+,O2+and CO2+for ion measurement and to resolve H and O(≥16 amu group)for ENA measurement.Here we present the design principle and describe our ground calibration of the MINPA. | LingGao Kong AiBing Zhang Zhen Tian XiangZhi Zheng WenJing Wang Bin Liu Peter Wurz Daniele Piazza Adrian Etter Bin Su YaYa An JianJing Ding WenYa Li Yong Liu Lei Li YiRen Li Xu Tan YueQiang Sun | 2020 | Earth and Planetary Physics2020，4，4： | 4 |
| 4 | A Satellite-borne Miniature Ion Mass Spectrometer for Space Plasma显示文摘The miniature design technology is an important trend in space exploration.Mass spectrometer is used extensively in the space environment detection.The miniature ion mass spectrometer utilizes a 127° cylindrical electrostatic analyzer accompanied with a Time of Flight(TOF)unit based on ultrathin carbon foil to measure the energy spectra and composition of space plasma.The Time of Flight technique has been used broadly in space plasma measurement.A new type of miniature method for the ion mass spectrometer is introduced.The total mass of the instrument is1.8 kg and the total power consumption is 2.0 W.The calibration results show that the energy measurement range is 8.71~43550eV,the energy resolution is 1.86%and the ion mass from 1 amu(1 amu= 1.67 × 10^(-27)kg) to 58 amu can be resolved by the miniature mass spectrometer.The miniature ion mass spectrometer also has a potential to be increased in the field of view by an electrostatic deflecting system to extend its application in space plasma detection.The miniature ion mass spectrometer has been selected for pre-study of Chinese Strategic Priority Research Program on Space Science. | KONG Linggao ZHANG Aibing ZHENG Xiangzhi AN Yaya WANG Wenjing TIAN Zhen GUAN Yibing LIU Chao DING Jianjing SUN Yueqiang | 2015 | 空间科学学报2015，35，6： | 2 |
| 5 | RBL-2H3 cell model based on VAMP-8-EGFP protein for rapid detection of different allergens显示文摘Allergic reactions are one of the most common adverse effects in clinical medicine.Anaphylactoid reactions are common immune responses that are often indistinguishable ftom allergic reactions[1]. The clinical symptoms of anaphylactoid and allergic reactions are similar,with allergy-related mediators released via degranulation of mast cells or basophils.However,the underlying mechanisms of anaphylactoid reactions are very different from allergic reactions. Unlike allergic reactions,anaphylactoid reactions occur on the first exposure to allergens without prior sensitization[2]. | Jiao Cao Pengyu Ma Wenjing Xue Yuanyuan Ding Yongjing Zhang Tao Zhang | 2018 | Acta Biochimica et Biophysica Sinica2018，50，12： | 2 |
| 6 | Experimental Verification on Conversion Mechanism of Calcium Aluminate Cement Hydrates显示文摘Calcium aluminate cement(CAC)is a commonly used binder for refractory castables.There has been a long-running debate on the transformation mechanisms of calcium aluminate cement hydrates through solid-state reaction or solutionprecipitation.In order to demonstrate the conversion mechanism of CaO Al2O310H2O(CAH10)to 3CaO Al2O36H2O(C3AH6)and Al2O33H2O(AH3),the CAC pastes cured at 10℃to produce CAH10 was further cured at 60℃with and without free water.The hydration of the pastes was halted by freezing-drying,and the phases and microstructure of hydrates were investigated by XRD and SEM,respectively.The results indicate that CAH10 converts into C3AH6 and AH3 in water presence at 60℃,but does not transform into C3AH6 and AH3 without water,demonstrating that conversion of CAH10 into C3AH6 and AH3 does not happen through solid-state reaction,but takes place through preceding dissolution of CAH10 and subsequent precipitation of AH3 and C3AH6 from the solution. | ZHANG Yang GU Wenjing LIU Kun DING Dafei WANG Qingfeng YE Guotian | 2019 | China's Refractories2019，28，2： | 2 |
| 7 | G protein-coupled receptor LGR6 is an independent risk factor for colon adenocarcinoma显示文摘LGR6 is a member of the G protein-coupled receptor family that plays a tumor-suppressive role in colon cancer. However, the relationship between LGR6 expression in patients and clinicopathological factors remains unclear. This study aimed to clarify whether the expression level of LGR6 is correlated with colon adenocarcinoma progression. Immunohistochemistry was used to detect LGR6 expression in colon adenoma tissues (n = 21), colon adenocarcinoma tissues (n = 156), and adjacent normal tissues (n = 124). The expression levels of LGR6 in colon adenoma and adenocarcinoma were significantly higher than those in normal colon epithelial tissues (P < 0.001). Low LGR6 expression predicted a short overall survival in patients with colon adenocarcinoma (log-rank test, P = 0.016). Univariate and multivariate survival analyses showed that, in addition to N and M classification, LGR6 expression served as an independent prognostic factor. Thus, low expression of LGR6 can be used as an independent prognostic parameter in patients with colon adenocarcinoma. | Wenjing Wang Shigang Ding Hejun Zhang Jun Li Jun Zhan Hongquan Zhang | 2019 | Frontiers of Medicine2019，13，4： | 2 |
| 8 | Responses of the Sea Surface Temperature and Suspended Matter Concentration to ENSO Events in the Bohai Sea显示文摘The sea surface temperature(SST)and sea surface suspended matter concentration data in the Bohai Sea were collected by multiple NOAA satellites from 1985 to 2018.The background calibration method was used to correct the systematic errors caused by the long-term observations through multiple NOAA satellites in this paper.Then,we studied the long-term variations of the sea surface temperature(SST)and sea surface suspended matter concentration(SSC)and their response to ENSO events in the Bohai Sea.Our results show that the SST and SSC of the Bohai Sea have been increasing since 1985,with an average rate of 0.04℃per year for SST,which is higher than the global average.The average increasing rate of SSC was 0.51 mg L^(-1)yr^(-1),which may be mainly due to the enhancement of winter monsoon in the Bohai.In winter,the SST and SSC of the Bohai Sea were higher in El Niño years than in La Niña years.In El Niño years,the ocean circulations were the main factor affecting the variation in SST.The robust circulation system caused by the strong winter monsoon enhances the water exchange between the cold water of the Bohai Sea and the warm water of the Yellow Sea,resulting in a higher SST in La Niña years.In summer,the SSTs of the Bohai Sea were lower in El Niño years than those in the La Niña years because of the decrease of the SST in the Western Pacific Ocean,the weakening of the subtropical high in the western Pacific,and its eastward shift caused by the El Niño events. | LIU Xue DING Dong LI Guangxue ZHANG Yang LIU Shidong WANG Nan ZHONG Yi YANG Xue PAN Yufeng YU Di ZHANG Lei XUE Wenjing | 2023 | Journal of Ocean University of China2023，22，3： | 1 |
| 9 | Interconnected MXene/Graphene Network Constructed by Soft Template for Multi‑Performance Improvement of Polymer Composites显示文摘The multi-functionalization of polymer composites refers to the ability to connect multiple properties through simple structural design and simultaneously achieve multi-performance optimization.The large-scale design and mass production to realize the reasonable structure design of multifunctional polymer composites are urgently remaining challenges.Herein,the multifunctional MXene/graphene/polymer composites with three-dimensional thermally and electrically conductive network structures are fabricated via the utilization of the microstructure of the soft template,and a facile dispersion dip-coating approach.As a result,the polymer composites have a multiperformance improvement.At the MXene and graphene content of 18.7 wt%,the superior throughplane thermal conductivity of polymer composite is 2.44 W m^(−1)K^(−1),which is 1118%higher than that of the polymer matrix.The electromagnetic interference(EMI)shielding effectiveness of the sample reaches 43.3 dB in the range of X-band.And the mechanical property of the sample has advanced 4 times compared with the polymer matrix.The excellent EMI shielding and thermal management performance,along with the effortless and easy-to-scalable producing techniques,imply promising perspectives of the polymer composites in the next-generation smart electronic devices. | Liyuan Jin Wenjing Cao Pei Wang Na Song Peng Ding | 2022 | Nano-Micro Letters2022，14，8： | 1 |
| 10 | Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase显示文摘DNA methylation 和 demethylation 在哺乳动物调整许多关键生物过程并且被连接到许多疾病。活跃 DNA demethylation 被相信被 TET 蛋白质和可以与在真菌催化 5caU 的去碳酸基到 U 的 isoorotate decarboxylase (IDCase ) 在顺序,结构和催化机制分享一些类似的通常认为的 DNA decarboxylase 催化。我们这里与 5caU, U,和禁止者 5-nitro-uracil 在 apo 形式或在建筑群从 Cordyceps militaris 和 Metarhizium anisopliae 报导野类型、变异的 IDCases 的结构。IDCases 采用一典型(β /α) amidohydrolase 总科和功能的 8 桶褶层作为 dimers。Zn 2+ 在活跃地点被绑并且由四严格地保存的残余协调了,一条毒蛇并且三他的。底层被几严格地保存的残余认出。在活跃地点的关键残余的功能的角色被 mutagenesis 和生物化学的研究验证。基于结构、生物化学的数据,我们在场第一次为 IDCases 的去碳酸基的新奇催化机制,它可能也适用于 amidohydrolase 总科的另外的成员。另外,我们 IDCases 能催化的生物化学的数据表演到有弱活动的 C 虽然的 5caC 的去碳酸基,它在为到由酶的 C 的 5caC 的直接去碳酸基的 vitro 证据是第一。这些调查结果在在哺乳动物的潜在的 DNA decarboxylase 的鉴定是珍贵的。 | Shutong Xu Wenjing Li Junjun Zhu Rong Wang Zheng Li Guo-Liang Xu Jianping Ding | 2013 | Cell Research2013，23，11： | 1 |
| 11 | UV light absorbers executing synergistic effects of passivating defects and improving photostability for efficient perovskite photovoltaics显示文摘Metal halide perovskite-based solar cells(PSCs) have rapidly-increased power conversion efficiency(PCE)exceeding 25% but poor stability especially under ultraviolet(UV) light. Meanwhile, non-radiative recombination caused by diverse defects in perovskite absorbers and related interfaces is one of the major factors confining further development of PSCs. In this study, we systematically investigate the role of 2-(2-hydroxy-5-methylphenyl)benzotriazole(UVP) additive in perovskite layers. By adjusting the amount of doped UVP, the quality of perovskite absorbers is significantly improved with enlarged grains, longer lifetime and diffusion length of charge carriers. Furthermore, UVP not only reduces defects for less nonradiative recombination, but also matches energy level alignment for efficient interfacial charge extraction. X-ray photoelectron spectroscopy confirms that N-donor of UVP molecule coordinates with undercoordinated Pb^(2+) on the surface. Interestingly, UVP incorporated in PbI_(2) protects the perovskite by absorbing UV through the opening and closing of the chelating ring. Eventually, the UVP treated PSCs obtain a champion PCE of 22.46% with remarkably enhanced UV stability, retaining over 90% of initial PCE after 60 m W/cm^(2) strong UV irradiation for 9 h while the control maintaining only 74%. These results demonstrate a promising strategy fabricating passivated and UV-resistant perovskite materials simultaneously for efficient and stable perovskite photovoltaics. | Jiale Li Wenjing Qi Yameng Li Sumin Jiao Hao Ling Peng Wang Xin Zhou Khumal Sohail Guangcai Wang Guofu Hou Jingshan Luo Ying Zhao Liming Ding Yuelong Li Xiaodan Zhang | 2022 | Journal of Energy Chemistry2022，31，4： | 1 |
| 12 | Effects of temperature, pH and light on the stability of aloin A and characterisation of its major degradation products显示文摘 | WENJING DING XIAOFANG WU JIASHENG ZHONG | 2014 | IntJ Food Sci Technol2014，49，7： | 1 |
| 13 | Recent progress in two-photon small molecule fluorescent probes for enzymes显示文摘Enzymes are macromolecular biological catalysts which can accelerate chemical reactions in living organisms. Almost all the physiological metabolism activities in the cell need enzymes to sustain life via rapid catalysis. Currently, medical research has proved that abnormal enzyme activity is associated with numerous diseases, such as Parkinson’s disease(PD), Alzheimer’s disease(AD) and cancers. On the other hand, early diagnosis of those diseases is of great significance to improve the survival rate and cure rate.In the current diagnostic tools, two-photon fluorescent probes(TPFPs) are developing rapidly due to their unique advantages, such as higher spatial resolution, deeper imaging depth, and lower biotoxicity.Therefore, the design and synthesis of two-photon(TP) small molecule enzymatic probes have broad prospects for early diagnosis and treatment of diseases. As of now, scientists have developed many TP small molecule enzymatic probes. This review aims to summarize the TP small molecule enzymatic probes and expound the reaction mechanism. | Ding Chen Wenjing Qin Haixiao Fang Lan Wang Bo Peng Lin Li Wei Huang | 2019 | Chinese Chemical Letters2019，30，10： | 1 |
| 14 | Exercise training effects on skeletal muscle plasticity and IGF-1 receptors in frail elders显示文摘 | Maria L. Urso Maria A. Fiatarone Singh Wenjing Ding William J. Evans Arthur C. Cosmas Thomas G. Manfredi | 2005 | AGE2005，，2： | 1 |
| 15 | Diagnostic Value of NPAR,MHR,GLU and Coronary Heart Disease Complicated with Type 2 Diabetes Mellitus显示文摘[Objectives]To explore the relationship between neutrophil percentage to albumin ratio(NPAR),monocyte to high density lipoprotein ratio(MHR),fasting blood glucose(GLU)and CAD+T2DM and its diagnostic value.[Methods]A total of 3937 patients who underwent coronary angiography in the Affiliated Hospital of Chengde Medical University from January 2016 to December 2018 were collected.The patients with Gensini score>0 and diabetes were selected as the experimental group(CAD+T2DM,n=756),and the patients with Gensini score=0 and without diabetes were taken as the control group(n=388),with a total of 1144 cases.The patient's medical record number,sex,age,contact number,biochemical test results,cardiac color ultrasound,coronary artery imaging and other data were recorded.NPAR,MHR,and GLU were calculated.A binary Logistic regression model was established combined with the receiver operating characteristic(ROC)curve.The predictive value of single index and joint test for CAD+T2DM was analyzed.[Results]The serum levels of NPAR,MHR and GLU in CAD+T2DM were significantly higher than those in the control group.Binary Logistic regression analysis showed that serum NPAR,MHR and GLU were risk factors for CAD+T2DM(P<0.05).The final prediction model is P=1/[1+e-(-3.722+0.014×NPAR+0.51×MHR+0.461×GLU)].ROC curve showed that the area under the curve of serum NPAR,MHR and GLU was 0.739,0.628 and 0.852,respectively,and the prediction probability of combined detection was 0.882,which was significantly higher than that of single index.[Conclusions]There was a close correlation between serum NPAR,MHR,GLU and CAD+T2DM in patients with coronary heart disease.The combined application of these indexes can significantly improve the predictive value of CAD+T2DM. | Wenjing ZHANG Chao LIU Fei SHI Wei QIN Zhenjiang DING Weichao SHAN | 2021 | Medicinal Plant2021，12，6： | 1 |
| 16 | Chemi- cal constituents of Aloe barbadensis Miller and theirin- hibitory effects on phosphodiesterase-4D 显示文摘 | Jiasheng Zhong Yiyou Huang Wenjing Ding | 2013 | Fitoterapia2013，，91： | 1 |
| 17 | Study on microstructure and mechanical property of high strength Mg-Nd-Zn-Zr alloy显示文摘 | Ding Wenjing Peng Liming Fu Penghuai | 2007 | Science Material Forum2007，，： | 1 |
| 18 | One-step synthesis of carbon-supported copper nanoparticles from biomass for N-arylation of pyrazole显示文摘Carbon-supported copper catalyst was prepared for the first time in one-step with copper nitrate and corn stalk through calcination under different temperatures. Uniformly dispersed nanoparticles were obtained and were identified to be Cu(0) and Cu(Ⅰ) in XRD patterns. Excellent catalytic activity and selectivity were achieved in the N-arylation of pyrazole under ligand and protection gas free conditions. About90.4% of product yield was achieved with only 0.5 mol% of copper catalyst(Cu-C-300), which was considerably more efficient than previous reports. XPS results suggested that the N-arylation of pyrazole activity was closely related to the surface Cu(Ⅰ) species. | Wenjing Li Yongjun Gao Pei Tang Yao Xu Ding Ma | 2018 | Journal of Energy Chemistry2018，27，3： | 1 |
| 19 | Mapping of individual sensory nerve axons from digits to spinal cord with the transparent embedding solvent system显示文摘Achieving uniform optical resolution for a large tissue sample is a major challenge for deep imaging.For conventional tissue clearing methods,loss of resolution and quality in deep regions is inevitable due to limited transparency.Here we describe the Transparent Embedding Solvent System(TESOS)method,which combines tissue clearing,transparent embedding,sectioning and block-face imaging.We used TESOS to acquire volumetric images of uniform resolution for an adult mouse whole-body sample.The TESOS method is highly versatile and can be combined with different microscopy systems to achieve uniformly high resolution.With a light sheet microscope,we imaged the whole body of an adult mouse,including skin,at a uniform 0.8×0.8×3.5μm^(3) voxel resolution within 120 h.With a confocal microscope and a 40×/1.3 numerical aperture objective,we achieved a uniform sub-micron resolution in the whole sample to reveal a complete projection of individual nerve axons within the central or peripheral nervous system.Furthermore,TESOS allowed the first mesoscale connectome mapping of individual sensory neuron axons spanning 5 cm from adult mouse digits to the spinal cord at a uniform sub-micron resolution. | Yating Yi Youqi Li Shiwen Zhang Yi Men Yuhong Wang Dian Jing Jiayi Ding Qingjie Zhu Zexi Chen Xingjun Chen Jun-Liszt Li Yilong Wang Jun Wang Hanchuan Peng Li Zhang Wenjing Luo Jian Q.Feng Yongwen He Woo-Ping Ge Hu Zhao | 2024 | Cell Research2024，34，2： | 0 |
| 20 | A novel gene-activated matrix composed of PEI/plasmid-BMP2 complexes and hydroxyapatite/chitosan-microspheres promotes bone regeneration显示文摘The incorporation of pro-osteogenic growth factors into bone graft materials to enhance bone regeneration is a key research area within the field of bone tissue engineering and regenerative medicine.However,growth factors directly incorporated in protein form are easily degraded,and have a limited active half-life,which cannot exert long-term and stable osteoinductive and oteoconductive effects.The combination of gene therapy and tissue engineering through gene-activated matrix(GAM)may provide a good alternative solution to overcome such limitations.Scaffold materials can be combined together with plasmid DNA and a chemical-based transfection agent to form GAM,through which transfected cells could secrete growth factors in a sustained manner over a longer time duration;thereby enabling bone graft materials to act as a repository of therapeutic genes,while providing structural support and a scaffold matrix for new bone tissue ingrowth.In this study,we prepared hydroxyapatite/chitosan-microspheres(HA/CS-MS)with microfabrication technology and emulsification method,and loaded the polyethylene imine/bone morphogenetic protein 2 plasmid(PEI/pBMP2)complexes with high transfection capacity(transfection efficiency up to 54.79%±4.95%),thus forming a novel GAM system with superior bone regeneration capacity—PEI/pBMP2-HA/CS-MS.The in vitro experiments in this study demonstrated that our GAM had excellent biocompatibility(with cell viability over 95%),and that the as-fabricated microsphere material possessed a nano-network fibrous structure similar to natural extracellular matrix(ECM),together with a higher surface area that can provide more cell adhesion sites.The sizes of the prepared microspheres were mainly distributed in the 160–180μm range,while the maximal loading rate of PEI-pBMP2 complexes was 59.79%±1.85%.As a loaded complexes system,the GAM can release plasmids in a slow controlled manner,effectively transfecting surrounding target cells(release effect for up to 21 days),while cells adherent to the material can also take up plasmids,resulting in sustained secretion of the target protein,thereby effectively promoting bone regeneration.In vivo data from micro-computed tomography(micro-CT)and histological staining showed that the use of the composite materials effectively enhanced bone regeneration in defect areas.These findings thus demonstrated that the novel GAM system had excellent osteoinductivity with significant clinical potential. | Ruyuan Ding Yajun Liu Dawei Cheng Gang Yang Wenjing Wu Haoran Du Xin Jin Yihan Chen Yuanyin Wang Boon Chin HENG Qing Yang Jianguang XU | 2022 | Nano Research2022，15，7： | 0 |
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