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| 1 | Anisotropic coding metamaterials and their powerful manipulation of differently polarized terahertz waves显示文摘Metamaterials based on effective media can be used to produce a number of unusual physical properties(for example,negative refraction and invisibility cloaking)because they can be tailored with effective medium parameters that do not occur in nature.Recently,the use of coding metamaterials has been suggested for the control of electromagnetic waves through the design of coding sequences using digital elements‘0’and‘1,'which possess opposite phase responses.Here we propose the concept of an anisotropic coding metamaterial in which the coding behaviors in different directions are dependent on the polarization status of the electromagnetic waves.We experimentally demonstrate an ultrathin and flexible polarization-controlled anisotropic coding metasurface that functions in the terahertz regime using specially designed coding elements.By encoding the elements with elaborately designed coding sequences(both 1-bit and 2-bit sequences),the x-and y-polarized waves can be anomalously reflected or independently diffused in three dimensions.The simulated far-field scattering patterns and near-field distributions are presented to illustrate the dual-functional performance of the encoded metasurface,and the results are consistent with the measured results.We further demonstrate the ability of the anisotropic coding metasurfaces to generate a beam splitter and realize simultaneous anomalous reflections and polarization conversions,thus providing powerful control of differently polarized electromagnetic waves.The proposed method enables versatile beam behaviors under orthogonal polarizations using a single metasurface and has the potential for use in the development of interesting terahertz devices. | Shuo Liu Tie Jun Cui Quan Xu Di Bao Liangliang Du Xiang Wan Wen Xuan Tang Chunmei Ouyang Xiao Yang Zhou Hao Yuan Hui Feng Ma Wei Xiang Jiang Jiaguang Han Weili Zhang Qiang Cheng | 2016 | Light(Science & Applications)2016，5，1： | 36 |
| 2 | Sulfur-based autotrophic denitrification from the micro-polluted water显示文摘Eutrophication caused by high concentrations of nutrients is a huge problem for many natural lakes and reservoirs. Removing the nitrogen contamination from the low C/N water body has become an urgent need. Autotrophic denitrification with the sulfur compound as electron donor was investigated in the biofilter reactors. Through the lab-scale experiment,it was found that different sulfur compounds and different carriers caused very different treatment performances. Thiosulfate was selected to be the best electron donor and ceramsite was chosen as the suitable carrier due to the good denitrification efficiency, low cost and the good resistibility against the high hydraulic loads. Later the optimum running parameters of the process were determined. Then the pilot-scale experiment was carried out with the real micro-polluted water from the West Lake, China. The results indicated that the autotrophic denitrification with thiosulfate as electron donor was feasible and applicable for the micro-polluted lake water. | Weili Zhou Xu Liu Xiaojing Dong Zheng Wang Ying Yuan Hui Wang Shengbing He | 2016 | Journal of Environmental Sciences2016，28，6： | 18 |
| 3 | Integrated genomic analysis identifies deregulated JAK/STAT-MYC-biosynthesis axis in aggressive NK-cell leukemia显示文摘好攻击的 NK 房间白血病(ANKL ) 是在从亚洲的人之中是更流行的 NK 房间瘤的一种稀罕形式并且中央并且南美洲。病人们通常在天以内死到月,甚至在收到迅速的治疗学的管理以后。这里,我们由集成整个染色体执行了 ANKL 的第一全面研究, transcriptome 并且定序指向,象功能的试金一样的 cytokine 数组。在 JAK-STAT 小径的变化在 48% 被识别(14/29 ) ANKL 病人,当细胞外的 STAT3 激发器 IL10 被 56 褶层的一般水准提高时(P < 0.0001 ) 在检查的所有病人的血浆。另外的经常变异的基因包括的 TP53 (34%) , TET2 (28%) , CREBBP (21%) 和 MLL2 (21%) 。耐心的 NK 白血病房间在多重新陈代谢的小径显示出 STAT3 phosphorylation, MYC 表示和 transcriptional 活动的突出的激活。机能上地, STAT3 激活和 MYC 表示为 ANKL 房间的增长和幸存是批评的。发信号的 STAT 调整了发信号的 MYC 抄写节目,和两 STAT, MYC 抄写被要求维持核苷酸合成和 glycolysis 的激活。一起, JAK-STAT 小径在 ANKL 为 genomic 改变和 IL10 刺激代表一个主要目标。这最新发现的 JAK/STAT-MYC-biosynthesis 轴可以在对待白血病的这种子类型为新奇治疗学的策略的发展提供机会。 | Liang Huang Dan Liu Na Wang Shaoping Ling Yuting Tang Jun Wu Lingtong Hao Hui Luo Xuelian Hu Lingshuang Sheng Lijun Zhu Di Wang Yi Luo Zhen Shang Min Xiao Xia Mao Kuangguo Zhou Lihua Cao Lili Dong Xinchang Zheng Pinpin Sui Jianlin He Shanlan Mo Jin Yan Qilin Ao Lugui Qiu Hongsheng Zhou Qifa Liu Hongyu Zhang Jianyong Li Jie Jin Li Fu Weili Zhao Jieping Chen Xin Du Guoliang Qing Hudan Liu Xin Liu Gang Huang Ding Ma Jianfeng Zhou Qian-fei Wang | 2018 | Cell Research2018，28，2： | 5 |
| 4 | Telomeres,cardiovascular aging,and potential intervention for cellular senescence显示文摘A consistent association has been observed between leukocyte telomere length(LTL)and atherosclerosis,but the mechanisms underlying these associations are still not well understood.Premature biology aging was evident in atherosclerotic plaques,characterized by reduced cell proliferation,irreversible growth arrest and apoptosis,and telomere attrition.As atherosclerosis is a state of chronic low-grade inflammation and increased oxidative stress,shortened LTL in patients with atherosclerosis might stem from the two sources,one is an accelerated rate in hematopoietic stem cells(HSCs)replication to replace leukocytes consumed in the inflammatory process,and another is the increase in the loss of telomere repeats per replication.Thus,diminished HSC reserves at birth and age-dependent telomere attrition afterward are mirrored in shortened LTL during the adulthood.In addition,the inter-individual variation of LTL in the general population can be partly explained by genetic factors regulating telomere maintenance and the rate of HSCs replication.Atherosclerosis is an aging-related disease,and practically all humans develop atherosclerosis if they live long enough.Here we overview the potential roles of LTL dynamics in the imbalance between injurious oxidative stress/inflammation and endothelial repair during the pathogenesis of age-related atherosclerosis,and discuss the possibility that preventing accelerated cellular senescence is a potential target in prevention of atherosclerosis. | ZHANG WeiLi HUI RuTai YANG ShuJun | 2014 | Science China(Life Sciences)2014，57，8： | 5 |
| 5 | Hot deformation behavior and workability characteristic of a fine-grained Mg–8Sn–2Zn–2Al alloy with processing map显示文摘The hot deformation behavior of a fine-grained Mg–8 Sn–2 Zn–2 Al(TZA822, in wt%) alloy was investigated in the temperature range of 150–350°C and the strain rate of 0.01–10 s^-1 employing thermomechanical simulator. In most of the cases, the material showed typical dynamic recrystallization(DRX) features i.e., a signal peak value followed by a gradual decrease or to reach a steady state. The work hardening rate was found to increase with decreasing temperature and increasing strain rate, while strain rates had great effects on work hardening behavior. Meanwhile, the constitutive analysis indicated that cross-slip of dislocations was likely to be the dominant deformation mechanism. In addition, the processing map at the strain of 0.1–0.7 showed two stability domains with high power dissipation efficiencies and the optimum hot working parameters for the studied alloy was determined to be 350°C/0.01 s^-1 and 350°C/10 s^-1, at which continuous DRX(CDRX) and discontinuous DRX(DDRX) as main softening mechanism. The instability regions occurred at 200–250°C/10 s^-1 and the main flow instability mechanism was twinning and/or flow localization bands, which were prone to induce cracks and caused in-consistent mechanical properties of the alloy. | Weili Cheng Yang Bai Shichao Ma Lifei Wang Hongxia Wang Hui Yu | 2019 | Journal of Materials Science & Technology2019，35，6： | 5 |
| 6 | 2021 Chinese consensus on the diagnosis and management of primary immune thrombocytopenia in pregnancy显示文摘Immune thrombocytopenia(ITP)is an acquired disease characterized by isolated thrombocytopenia,which is one of the most common causes of thrombocytopenia during pregnancy.Women with ITP who have severe thrombocytopenia are at an increased risk for life-threatening obstetric complications.Therefore,we established this consensus statement on the diagnosis and management of ITP during pregnancy(detailed information is available in the Supplementary File,http://gffzz16e312a87a7141a5hwoofw6cnbpku6vxf.ffgz.tsg.suse.edu.cn/A978). | Zhang Xiaohui Chen Fangping Chen Xiequn Cheng Yunfeng Fang Meiyun Feng Jianming Fu Haixia Gao Hong Han Yue He Aili Hou Ming Hu Yu Huang Ruibin Huang Wenrong Jing Zhicheng Kong Peiyan Liang Aibin Liang Meiying Liu Daihong Liu Junling Liu Lin Liu Xiaowei Ma Liangming Mei Heng Ni Heyu Niu Ting Peng Jun Qiao Jianlin Ren Jinhai Song Yongping Tang Liang V Tong Tong Wang Shaoyuan Wang Xin Wang Zhao Wei Hui Wu Depei Wu Guangsheng Xu Caigang Xu Xue Xu Yajing Yang Linhua Yang Renchi Yang Tonghua Yin Chenghong Yu Li Zhang Guangsen Zhang Lei Zhang Liansheng Zhang Xi Zhao Weili Zhao Yongqiang Zhou Daobin Zhou Hu Zhou Zeping Zhu Tienan Wang Jianliu Huang Xiaojun | 2022 | Chinese Medical Journal2022，，8： | 2 |
| 7 | Contribution of lipid to physicochemical properties and Mantou - making quality of wheat flour显示文摘 | Hui Sun Shuping Yan Weili Jiang | 2010 | Food Chemistry2010，，121： | 1 |
| 8 | Prevalence of and risk factors for peripheral arterial disease in the patients with hypertension among Han Chinese显示文摘 | XiaoMin Yang Kai Sun WeiLi Zhang HaiYing Wu HuiMin Zhang RuiTai Hui | 2007 | Journal of Vascular Surgery2007，，： | 1 |
| 9 | Tumor cell α3β1 integrin and vascular laminin-5 mediate pulmonary arrest and metastasis 显示文摘 | Hui W Weili F Jae HI | 2004 | J Cell Biology2004，164，6： | 1 |
| 10 | Determination of nighttime VTEC average in the Klobuchar ionospheric delay model显示文摘The Klobuchar model has been widely used to correct the ionospheric delay in applications. However, the NVTEC(Nighttime Vertical Total Electron Content) of the Klobuchar model employs an empirical constant of 9 TECU(Total Electron Content Unit) at L1 frequency. In this paper, the rationality and reliability of the nighttime constant setting are investigated using the GIM(Global Ionosphere Map) product of the IGS(International GNSS Service) from 1998 to 2015. Our study indicates that the suitable time span of NVTEC average in nighttime should be between 20:00 and 06:00 LT(local time). The NVTEC is highly correlated with seasons, having positive extremes in spring and autumn and negative extremes in summer through the mean values in all latitudes. In addition to seasonal dependence, solar activity in the solar cycle 23 strongly influences NVTEC as well and leads to its variation within a range between 25 and30 TECU in spring and autumn at solar maximum, which is about 1.5 times greater than that in summer and winter. The NVTEC also has a dependence on the latitude at solar maximum, with the mean value from 30 TECU in low latitudinal regions to 15 TECU in high latitudinal regions. Therefore, these results demonstrate that the nighttime VTEC has much greater deviations from the imperial constant in the Klobuchar model, and the newly estimated constant is expected to bring improvement to the predictability of the Klobuchar ionospheric delay model in nighttime. | Weili Zhou Shuli Song Qinming Chen Na Cheng Hui Xie | 2018 | Geodesy and Geodynamics2018，9，2： | 1 |
| 11 | Plasma Uric Acid and Hypertension in a Chinese Community: Prospective Study and Metaanalysis显示文摘 | Zhang Weili Sun Kai Yang Ying Zhang Hongye Hu Frank B Hui Rutai | 2009 | Clinical Chemistry2009，，： | 1 |
| 12 | Contribution of lipid to physicochemical prop- erties and Mantou- making quality of wheat flour 显示文摘 | Sun Hui Yan Shuping Jiang Weili | 2010 | Food Chemistry2010，121，2： | 1 |
| 13 | Identifying the potential transcriptional regulatory network in Hirschsprung disease by integrated analysis of microarray datasets显示文摘Objective Hirschsprung disease(HSCR)is one of the common neurocristopathies in children,which is associated with at least 20 genes and involves a complex regulatory mechanism.Transcriptional regulatory network(TRN)has been commonly reported in regulating gene expression and enteric nervous system development but remains to be investigated in HSCR.This study aimed to identify the potential TRN implicated in the pathogenesis and diagnosis of HSCR.Methods Based on three microarray datasets from the Gene Expression Omnibus database,the multiMiR package was used to investigate the microRNA(miRNA)-target interactions,followed by Gene Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)enrichment analyses.Then,we collected transcription factors(TFs)from the TransmiR database to construct the TF-miRNA-mRNA regulatory network and used cytoHubba to identify the key modules.Finally,the receiver operating characteristic(ROC)curve was determined and the integrated diagnostic models were established based on machine learning by the support vector machine method.Results We identified 58 hub differentially expressed microRNAs(DEMis)and 16 differentially expressed mRNAs(DEMs).The robust target genes of DEMis and DEMs mainly enriched in several GO/KEGG terms,including neurogenesis,cell-substrate adhesion,PI3K-Akt,Ras/mitogen-activated protein kinase and Rho/ROCK signaling.Moreover,2 TFs(TP53and TWIST1),4 miRNAs(has-miR-107,has-miR-10b-5p,has-miR-659-3p,and has-miR-371a-5p),and 4 mRNAs(PIM3,CHUK,F2RL1,and CA1)were identified to construct the TF-miRNA-mRNA regulatory network.ROC analysis revealed a strong diagnostic value of the key TRN regulons(all area under the curve values were more than 0.8).Conclusion This study suggests a potential role of the TF-miRNA-mRNA network that can help enrich the connotation of HSCR pathogenesis and diagnosis and provide new horizons for treatment. | Wenyao Xu Hui Yu Dian Chen Weikang Pan Weili Yang Jing Miao Wanying Jia Baijun Zheng Yong Liu Xinlin Chen Ya Gao Donghao Tian | 2023 | World Journal of Pediatric Surgery2023，6，2： | 0 |
| 14 | Realization of a novel Ag/SnO_2 electrical contact material with microscopic fiber-like structure显示文摘According to the principle that fiber-like arrangement of reinforcing particles SnO2 paralleling to the direction of current is propitious to the electrical and mechanical performance of the electrical contact materials, we proposed and reported a novel precursor route used to prepare Ag/SnO2 electrical contact material with fiberlike arrangement of reinforcing nanoparticles. The mechanism for the formation of fiber-like arrangement of reinforcing nanoparticles in Ag/SnO2 electrical contact material was also discussed. The as-prepared samples were characterized by means of scanning electron microscope (SEM),optical microscope (OM),energy-dispersive X-ray spectroscopy (EDX),MHV2000 microhardness test,and double bridge tester. The analysis showed that the as-prepared Ag/SnO2 electrical contact material with fiber-like arrangement of reinforcing nanoparticles exhibits a high elongation of 24 %,a particularly low electrical resistivity of 2.08 μΩ· cm,and low arcing energy,and thus has considerable technical,economical and environmental benefits. | Chen Lawson Liu Weili Tian Hui | 2013 | Engineering Sciences2013，11，3： | 0 |
| 15 | Baseline establishment for metals in the western Clarion-Clipperton Zone显示文摘Resource exploitation in the Clarion-Clipperton Zone(CCZ)is of major research interest worldwide,but its influence on the environment is poorly understood,especially due to the lack of baseline values for metals in the surrounding sediment.This work aimed to establish the baseline values of 17 metals(Ba,Ca,K,Mg,Mn,Na,Ag,As,B,Cd,Co,Cr,Cu,Hg,Ni,Pb,and Zn)using normalization,the cumulative frequency curve method considering a total of 172 samples taken from 8 multitube cores and 1 box sediment core collected in the western CCZ during the COMRA-45 cruise campaign from August to September 2017.The baseline values of the evaluated metals were as follows:1932 mg/kg for Ba,29512 mg/kg for Ca,18150 mg/kg for K,17120 mg/kg for Mg,6747 mg/kg for Mn,28546 mg/kg for Na,0.571 mg/kg for Ag,5.00 mg/kg for As,94.4 mg/kg for B,0.626 mg/kg for Cd,104 mg/kg for Co,76.1 mg/kg for Cr,370 mg/kg for Cu,0.028 mg/kg for Hg,190 mg/kg for Ni,27.5 mg/kg for Pb and 156 mg/kg for Zn.Our findings would fill the baseline value gap in the study area and further improve accuracy of environmental impact assessments on the impact of resource exploitation. | Cai Lin Yang Liu Ronggen Jiang Jinmin Chen Baohong Chen Weili Wang Kaiwen Zhou Hui Lin | 2022 | Acta Oceanologica Sinica2022，41，11： | 0 |
| 16 | Numerical simulation on centrifugal pump compressible flow field with different gas volume fractions显示文摘In order to study the influence of gas-liquid two-phase flow on the performance and internal flow field of a centrifugal pump,the steady three-dimensional flow with different gas volume fractions was simulated by applying the Reynolds-average N-S equation and mixture gas-liquid two-phase flow model,and the compressibility of gas was taken into consideration in the simulation. Then the centrifugal pump characteristic and the gas distribution law in different gas volume fractions were analyzed. The computational results show that gas volume fraction has a certain influence on the performance of the centrifugal pump,and the efficiency and head of the pump are on the decline with the increase of it.Static pressure in the impeller increases in the radial direction,but the pressure gradient in the flow direction is different under the different gas volume fractions. The gas volume is distributed mainly in the ipsilateral direction of impeller back shroud in the flow channel of the volute. On the suction side of the blade inlet there is an obvious low-pressure area,which causes bubbles agglutination and higher gas volume fraction. With the gas entering passage flow,gas volume fraction in the suction decreases and the pressure surface rises gradually. Higher gas volume fraction causes air blocking phenomenon in the flow passage and the discharge capacity reduces. The increase of gas volume makes the turbulent motion within the impeller more and more intense,which leads to more and more energy loss. | WANG Like LIAO Weili LU Jinling LUO Xingqi RUAN Hui ZHAO Yaping WANG Jing | 2019 | 排灌机械工程学报2019，37，2： | 0 |
| 17 | Fixed-point Monitoring of Vaccine Immune Effects on Severe Animal Diseases in Livestock and Poultry Breeding Fields显示文摘In order to reveal the immune antibody levels and immune effect of livestock and poultry in the locality,we performed antibody surveillance on severe animal diseases in 17 livestock and poultry fields in six administrative districts of Wuhan City. The results showed that the vaccines had a good protective efficacy on highly pathogenic avian influenza( HPAI) and Newcastle disease( ND) in Wuhan City. The whole antibody levels kept above the ministerial standard( > 70%).However,the vaccine immunity of porcine reproductive and respiratory syndrome( PRRS),swine fever( SF) and foot and mouth disease( FMD) was still poorly protective. The data indicated that the vaccines are protecting the severe animal diseases well,but there are still some potential security holes in some administrative districts. | Zhang Sihua Ruan Zheng Yin Weili Wan Yun Zhou Hui Gong Shiyu | 2014 | Animal Husbandry and Feed Science2014，6，5： | 0 |
| 18 | Role of mitogen- and stress-activated kinases in inflammatory arthritis显示文摘Lysophosphatidic acid(LPA) is a pleiotropic lipid mediator that promotes motility, survival, and the synthesis of chemokines/cytokines in human fibroblast-like synoviocytes(FLS) from patients with rheumatoid arthritis. LPA activates several proteins within the mitogen activated protein(MAP) kinase signaling network, including extracellular signal-regulated kinases(ERK) 1/2 and p38 MAP kinase(MAPK). Upon docking to mitogen- and stress-activated kinases(MSKs), ERK1/2 and p38 MAPK phosphorylate serine and threonine residues within its C-terminal domain and cause autophosphorylation of MSKs. Activated MSKs can then directly phosphorylate c AMP response element-binding protein(CREB) at Ser133 in FLS. Phosphorylation of CREB by MSKs is essential for the production of pro-inflammatory and anti-inflammatory cytokines. However, other downstream effectors of MSK1/2 such as nuclear factor-kappa B, histone H3, and high mobility group nucleosome binding domain 1 may also regulate gene expression in immune cells involved in disease pathogenesis. MSKs are master regulators of cell function that integrate signals induced by growth factors, pro-inflammatory cytokines, and cellular stresses, as well as those induced by LPA. | Sylvain G Bourgoin Weili Hui | 2015 | World Journal of Pharmacology2015，4，4： | 0 |
| 19 | Preparation and Luminescence Properties of Color-tunable Single-phased LaPO4:Eu3+/Tb3+ Phosphors显示文摘 | DONG Weili ZHANG Xiyan SHI Hui WANG Nengli ZHANG Wenmin LI Liang XUE Qingxue | 2016 | Chemical Research in Chinese Universities2016，32，2： | 0 |
| 20 | 敲入亨廷顿基因的猪模型再现了亨廷顿病的选择性神经退化症状显示文摘文章简介亨廷顿舞蹈病(Huntington’s disease, HD)是一种遗传性神经退行性疾病,是由一种编码导致脑细胞死亡的毒性蛋白的基因引起的。尽管转基因小鼠已被广泛用于构建神经退行性疾病模型,但是它们缺乏在人类大脑中观察到的典型神经变性或明显的神经元缺失。 | Sen Yan Zhuchi Tu Zhaoming Liu Nana Fan Huiming Yang Su Yang Weili Yang Yu Zhao Zhen Ouyang Chengdan Lai Huaqiang Yang Li Li Qishuai Liu Hui Shi Guangqing Xu Heng Zhao Hongjiang Wei Zhong Pei 李世华 赖良学 李晓江 | 2019 | 科学新闻2019，0，2： | 0 |
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