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| 1 | Determining the microstructure and properties of magnesium aluminum composite panels by hot rolling and annealing显示文摘The researchers made magnesium aluminum composite panels by asymmetric metal packaging and studied rolling temperature,holding time,and high temperature heat treatment,such as short time and low temperatures over long periods of time parameters under the new preparation method.We tested the new magnesium aluminum composite panels’tensing properties and bending performance by using scanning electric mirror and EDS.It is concluded that the new magnesium aluminum composite panels’elongation is 24%under the tensile strength of 260 MPa.Regarding performance when compared with other methods,traditional magnesium aluminum composite panels’elongation is 10%,which shows its advanced nature.At the same time,bending performance test showed that the combination of the composite board has higher performance,offering the reference value for the preparation of magnesium–aluminum composite plate. | Zilong Zhao Qiang Gao Junfeng Hou Ziwei Sun Fei Chen | 2016 | Journal of Magnesium and Alloys2016，4，3： | 4 |
| 2 | Determination of dioxin-like polychlorinated biphenyls in soil and moss from Fildes Peninsula,Antarctica显示文摘Dioxin-like polychlorinated biphenyls(PCBs) are a class of toxic and persistent chemicals that are often found in the environment.The determination of dioxin-like PCBs in Fildes Peninsula,Antarctica,is reported in this paper.Dioxin-like PCBs were widely distributed in Antarctic soil and moss with concentration of 2.23-27.2 pg/g in soil and 10.4-812 pg/g in moss.The highest concentrations were found in the Ardley Island area and the lowest concentrations on the west coast.The contribution of PCB-118 to the ∑12PCBs ranged from 36.0% to 69.6% in soil,and 17.2% to 43.4% in moss.The congener specific patterns in soil and moss were similar.Long-range atmospheric transport is thought to be the main source of PCBs detected on King George Island.The ∑12PCBs toxic equivalent(TEQ) in soil was 0.400×10?3 to 516×10?3 pg(TEQ)/g with a mean value of 147×10?3 pg(TEQ)/g.PCB-126 had the largest contribution(81.1%) to the ∑12PCBs TEQ in soil.The ∑12PCBs TEQ in moss ranged from 2.90×10?3 to 1.19 pg/g with a mean value of 0.482 pg/g.PCB-126 was also the largest contributor(91.4%) to the ∑12PCBs TEQ in moss.The mean TEQ in moss was about 40 times that in soil. | WANG Qiang SHI YeHong HU JianXin YAO ZiWei FANG XueKun DONG YiAn | 2012 | Chinese Science Bulletin2012，57，9： | 3 |
| 3 | Modulation effects of hexamethylene bisacetamide on growth and defferentiation of cultured human malignant glioma cells 显示文摘 | Xiaonan Li Ziwei Du Qiang Huang | 1996 | J Neurosurgery1996，84，： | 1 |
| 4 | A joint call for actions to advance taxonomy in China显示文摘Taxonomy plays an important role in understanding the origin, evolution, and ecological functionality of biodiversity. There are large number of unknown species yet to be described by taxonomists, which together with their ecosystem services cannot be effectively protected prior to description. Despite this, taxonomy has been increasingly underrated insufficient funds and permanent positions to retain young talents. Further, the impact factordriven evaluation systems in China exacerbate this downward trend, so alternative evaluation metrics are urgently necessary. When the current generation of outstanding taxonomists retires,there will be too few remaining taxonomists left to train the next generation. In light of these challenges, all co-authors worked together on this paper to analyze the current situation of taxonomy and put out a joint call for immediate actions to advance taxonomy in China. | Chaodong Zhu Arong Luo Ming Bai Michael COrr Zhonge Hou Siqin Ge Jun Chen Yibo Hu Xuming Zhou Gexia Qiao Hongzhi Kong Limin Lu Xiaohua Jin Lei Cai Xinli Wei Ruilin Zhao Wei Miao Qingfeng Wang Zhongli Sha Qiang Lin Meng Qu Jianping Jiang Jiatang Li Jing Che Xuelong Jiang Xiaoyong Chen Lianming Gao Zongxin Ren Chunlei Xiang Shixiao Luo Donghui Wu Dong Liu Yanqiong Peng Tao Su Chenyang Cai Tianqi Zhu Wanzhi Cai Xingyue Liu Hu Li Huaijun Xue Zhen Ye Xuexin Chen Pu Tang Shujun Wei Hong Pang Qiang Xie Feng Zhang Feng Zhang Xianjin Peng Aibing Zhang Taiping Gao Changfa Zhou Chen Shao Libin Ma Zhaoming Wei Yunxia Luan Ziwei Yin Wu Dai Cong Wei Xiaolei Huang Jingxian Liu Xiangsheng Chen Tianci Yi Zhisheng Zhang Zhulidezi Aishan Qin Li Hongying Hu | 2022 | Zoological Systematics2022，47，3： | 1 |
| 5 | Radio-frequency system of the high energy photon source显示文摘Purpose High energy photon source is a 6 GeV diffraction-limited storage ring light source currently under construction in Beijing.A low-frequency fundamental radio-frequency(rf)system of 166.6 MHz was proposed to accommodate the accelerator physics design.Superconducting rf(srf)technologies were chosen for the storage ring rf accompanied by solid-state power amplifiers and digital low-level rf controls.The design of the rf system was completed,and the parameters are frozen.Elucidation of the rf design with key parameters is desired.Methods The requirements from the accelerator physics design will be presented followed by the detailed rf design.The logic behind the choice of key rf parameters is elaborated.The configuration of the entire rf system is presented.Results and conclusions The fundamental srf cavity of 166.6 MHz was designed to accelerate the ultrarelativistic electron beam.Heavy damping of higher-order modes in these cavities is required to avoid the coupled bunch instabilities.An active third harmonic srf of 499.8 MHz was adopted to realize the required rf gymnastics.Normal-conducting 5-cell cavities will be used for the booster rf.Solid-state amplifiers of 2.4 MW in total will be installed at HEPS to drive these cavities in the booster and the storage ring.A digital low-level rf system will be used to regulate rf field inside each cavity with high stabilities.The rf configuration during the commissioning and the operation scenarios are also presented. | Pei Zhang Jin Dai Ziwei Deng Lin Guo Tongming Huang Dongbing Li Jian Li Zhongquan Li Haiying Lin Yuanli Luo Qiang Ma Fanbo Meng Zhenghui Mi Qunyao Wang Haisheng Xu Xinying Zhang Facheng Zhao Hongjuan Zheng | 2023 | Radiation Detection Technology and Methods2023，7，1： | 1 |
| 6 | Palladium-catalyzed intermolecular C–H amidation of indoles with sulfonyl azides显示文摘A new kind of intermolecular indole C–H amidation reaction catalyzed by the most frequently used palladium catalyst has been developed.Sulfonyl azide was employed as an innovative nitrogen source and environmentally benign nitrogen was produced as the only byproduct. | Ziwei Hu Shuang Luo Qiang Zhu | 2015 | Science China Chemistry2015，58，8： | 1 |
| 7 | Development of a 500-MHz waveguide directional coupler with high directivity for HEPS显示文摘Purpose In order to achieve a high-precision measurement of the incident and the reflected power,a WR1800 rectangular waveguide directional coupler with high directivity and high power level has been in-house developed.Multiple couplers will be installed in the 500-MHz high-power radio-frequency transmission lines delivering 200-kW continuous-wave power for the High Energy Photon Source(HEPS).Methods The directional coupler adopts the design scheme of primary and secondary transmission lines and coaxial coupling-head structure.The shape and dimensional parameters of the coupling head were carefully optimized by using microwave simulation codes.An optimum directivity of 64 dB was achieved in simulations.Results and conclusions A prototype coupler was subsequently manufactured,and its directivity was measured to be 48.2 dB following a rigorous calibration procedure,largely exceeding the design goal and the commercial product.The coupler was then connected to an existing 500-MHz klystron system,and a high-power test with short-circuit termination was conducted.The high directivity of the coupler was confirmed up to 200 kW.During the 6 hours of power aging with continuous-wave 200 kW in a standing-wave setup,no performance degradation was observed on the coupler.The coupler temperature was measured to be 20◦C above the ambient environment.The design requirements were comfortably fulfilled.These constitute thefirst in-house development of a large-size waveguide directional coupler with high directivity and high power level for HEPS.The design,fabrication,and performance tests of the directional coupler are presented. | Yuanli Luo Jian Li Pei Zhang Qiang Ma Haiying Lin Tongming Huang Fanbo Meng Facheng Zhao Ziwei Deng | 2022 | Radiation Detection Technology and Methods2022，6，3： | 1 |
| 8 | PH_3 monitoring in Arctic and Dalian bay areas显示文摘In this paper,we use pre-column 2 times low-temperature cryo-trap enrichment—gas chromatography(GC) /nitrogen and phosphoms detector(NPD)to detect and analyze phosphine in Arctic pole area forthe first time.The results show phosphine exists in all of the samples in Arctic pole biosphere and phosphineconcentration in Arctic atmosphere is between 18.54~132.18 ng/m^3,almost the same as that inAntarctic atmosphere;phosphine concentration in Dalian bay sea surface sediments is between 116.8~554.3 ng/kg,almost the same as that reported in Jiao-zhou bay.Our research of phosphine will shednew light on the mechanisms showing how the phosphorus supplement influences the biogeochemical cycleand global warming. | 封颖 Wang Qiang Yao Ziwei Geng Jinju | 2010 | High Technology Letters2010，16，4： | 0 |
| 9 | 3D-printed,bi-layer,biomimetic artificial periosteum for boosting bone regeneration显示文摘Periosteum,a membrane covering the surface of the bone,plays an essential role in maintaining the function of bone tissue—and especially in providing nourishment and vascularization during the bone regeneration process.Currently,most artificial periostea have relatively weak mechanical strength and a rapid degradation rate,and they lack integrated angiogenesis and osteogenesis functions.In this study,a bi-layer,biomimetic,artificial periosteum composed of a methacrylated gelatin–nano-hydroxyapatite(GelMA-nHA)cambium layer and a poly(N-acryloyl 2-lycine)(PACG)-GelMA-Mg^(2+)fibrous layer was fabricated via 3D printing.The GelMA-nHA layer is shown to undertake the function of improving osteogenic differentiation of rat bone marrow mesenchymal stem cells with the sustainable release of Ca^(2+) from nHA nanoparticles.The hydrogen-bonding-strengthened P(ACG-GelMA-L)-Mg^(2+)hydrogel layer serves to protect the inner defect site and prolong degradation time(60 days)to match new bone regeneration.Furthermore,the released magnesium ion exhibits a prominent effect in regulating the polarization phenotype of macrophage cells into theM2 phenotype and thus promotes the angiogenesis of the human umbilical vein endothelial cells in vitro.This bi-layer artificial periosteum was implanted into a critical-sized cranial bone defect in rats,and the 12-week post-operative outcomes demonstrate optimal new bone regeneration. | Yage Sun Ziwei Gao Xiaoping Zhang Ziyang Xu Yahan Zhang Binbin He Rong Yang Qian Zhang Qiang Yang Wenguang Liu | 2022 | Bio-Design and Manufacturing2022，5，3： | 0 |
| 10 | Matrix-bound phosphine in Ny-Alesund Area of Arctic显示文摘Phosphine,a ubiquitous trace gas in the atmosphere,acts as a carrier of gasous phosphorus in thebiogeochemical cycle.The research of phosphine will show new light on the mechanisms of how the phos-phorus supplement influence the biogeochemical cycle and global warming.In this paper,we detect thephosphine in Arctic Pole area for the first time.The result shows that matrix-bound phosphine(MBP)ex-ists in all the samplings.Phosphine distributions varied with different environmental origins.Averagephosphine concentrations in tundra soil,lake sediments,sea sediments,seabird-droppings and deerguanos were 14.17ng/kg dry,35.44 kg dry,67.20 kg dry,32.9 ng/kg dry,and 25.52 ng/kg dry re-spectively.Correlation analysis shows that there is an obviously positive correlation between Porg andMBP.It could be concluded that anaerobic decomposition of Porg and the mechano-chernistry action of therock probably are the possible reasons explaining the mechanism of MBP production in Arctic Pole area. | 封颖 Wang Qiang Yao Ziwei Geng Jinju | 2009 | High Technology Letters2009，15，3： | 0 |
| 11 | Direct Determination of Migration Amount of Fluorescent Whitening Agents in Facial Mask显示文摘 | YU Yang WANG Xinghua FEI Qiang YU Yong TIAN Sizhu WANG Kun JIANG Jia SONG Daqian YU Aimin ZHANG Ziwei | 2017 | Chemical Research in Chinese Universities2017，33，3： | 0 |
| 12 | Co-delivery of nigericin and decitabine using hexahistidine-metal nanocarriers for pyroptosis-induced immunotherapeutics显示文摘Pyroptosis provides a new window for relieving the tumor immunosuppressive microenvironment(TIM)and promoting systemic immune responses for tumor treatments.However,gasdermin D(GSDMD),a key protein in the pyroptosis process mediated by caspase-1,is low expressed in the majority of tumor cells and small-molecule inhibitors of DNA methylation suffer from nonspecific or single-function defects.To address these issues,hexahistidine(His6)-metal assembly(HmA)was employed as the drug delivery vector to load nigericin(Nig)and decitabine(DAC)affording a dual-drug delivery system(Nig^(+)DAC)@HmA.The(Nig^(+)DAC)@HmA nanoparticles are efficiently internalized by cells through endocytosis,easily escape from the lysosome,and are highly distributed in the tumor sites.DAC up-regulates the expression of GSDMD which is then cleaved by the nucleotide-binding oligomerization domain-like receptor protein 3(NLRP3)inflammasome and caspase-1 protein activated by Nig.Effective cancer cell pyroptosis is thus achieved and induces a significant systemic antitumor immunity for impressive tumor suppression with negligible side effects in vivo.Our results suggest that such an easy-to-manipulate self-assembled nano-system(Nig^(+)DAC)@HmA provides a new anticancer path by enhancing pyroptosis through reinforced inflammation. | Qiang Niu Yu Liu Yujing Zheng Ziwei Tang Yuna Qian Ruogu Qi Jianliang Shen Ping Zhao | 2022 | Acta Pharmaceutica Sinica B2022，12，12： | 0 |
| 13 | Enhancing gene editing efficiency for cells by CRISPR/Cas9 system-loaded multilayered nanoparticles assembled via microfluidics显示文摘Most non-viral carriers for in vitro delivery of nucleic acids suffer from low efficiency of introducing m RNA and other nucleic acids,especially large m RNA.Cas9 protein is the nuclease part of the powerful gene-editing tool,CRISPR/Cas9 system,Cas9 m RNA is particularly large,thus presents a big challenge for delivery.We assembled a multilayered biodegradable nanocarrier to load Cas9 m RNA inside to protect Cas9 m RNA from degradation.We used a microfluidic chip to synthesize a small,positively charged,and degradable core to attract negatively charged Cas9 m RNA.The microfluidic assembly allows the core to be small enough to incorporate into a cationic liposome.The multilayered nanocarriers elevated the delivery efficiency of Cas9 m RNA by over 2 folds and increased the expression by over 5 folds compared to commercially used non-viral carriers.In addition,the multilayered nanocarriers do not require reduced serum medium for transfection.When using the standard complete medium for transfection,the multilayered nanocarriers could increase the expression of Cas9 m RNA by over 15 folds compared to commercially used non-viral carriers.The co-delivery of Cas9 m RNA and sg RNA via LRC elevated the gene-editing efficiency by 3 folds compared to that via commercially used non-viral carriers.Based on the higher transfection efficiency of Cas9 m RNA/sg RNA than commercially used non-viral carriers,these multilayered nanocarriers may have a good prospect as efficient commercial delivery carriers for Cas9 m RNA/sg RNA and other nucleic acids. | Xuanyu Li Qiang Feng Ziwei Han Xingyu Jiang | 2021 | Chinese Journal of Chemical Engineering2021，34，10： | 0 |
| 14 | A Spatial Supply-Demand Imbalance Between Rural Primary and Secondary Schools in Shaanxi Province Based on Road Network Analysis显示文摘It is of great significance to optimize the spatial matching of basic education facilities in rural areas and promote the equalization of urban and rural basic public services and the overall revitalization of rural areas.Based on the theory of spatial accessibility and spatial balance of supply and demand,this paper constructs the evaluation system of rural basic education facilities and layout rationality.In this study,we took 42 primary and secondary schools and 2089 rural areas with concentrated population in six township areas of Hancheng City as the research subjects.We used ArcGIS network analysis,population coupling model,and other methods,from the administrative scale and rural population concentration area scale for evaluation.The accessibility of basic education facilities and its coupling relationship with the spatial distribution of student population describe the spatial and geographical pattern of basic education facilities in rural areas.The results show that the accessibility of rural administrative scale and the spatial balance of supply and demand of population concentration area scale are associated with great problems,the differences between towns are obvious,and the overall level of the best performing towns is still low.On the scale of population concentration area,the overall coupling degree is too low,the'dislocation'distribution of educational facilities and student population is obvious,and the matching degree of the student population and school in different towns is significantly different,showing a more obvious'core-periphery'spatial structure characteristics centered on the eastern and southeast regions.The terrain characteristics of rural areas in Shaanxi province are prominent,and the accessibility of the road network is particularly significant.Therefore,optimizing the construction of rural roads and optimizing school layout according to local conditions will become an important solution to promote the balanced allocation of basic education resources in Shaanxi province. | Ziwei Qiang Bei Jin Shiyuan Xu | 2022 | Journal of Contemporary Educational Research2022，6，2： | 0 |
| 15 | RF design of a compact 648 MHz single spoke cavity at CSNS显示文摘Purpose In order to increase CSNS beam power from 100 to 500 kW,the linac injection energy needs to be increased from 80 to 300 MeV.The combined layout of superconducting spoke cavities and lliptical cavities will be adopted to accelerate H-beam to 300 MeV.In this paper,a compact single spoke cavity withφ50-mm beam aperture was proposed,with the RF performance of the spoke cavity optimized to E_(p)/E_(acc).<5,E_(p)/E_(acc)<9,as well as the good multipacting behavior.Methods CST Microwave Studio was used to optimize the RF performance(E_(peak)/E_(acc),B_(peak)/E_(acc) R/Q)with cavity geometry parameters.After electromagnetic design was finished,multipacting behavior was studied with CST Particle Studio module,and cavity shape modification was made to get a reasonablevalue.Results The simulation got optimum results of E_(peak)/E_(acc)=4.97 and B_(peak)/E_((acc)=8.42 mT/(MV/m),and themax is 1.52at E_(acc)=7.74 MV/m.Conclusion A 648 MHzβ=0.4 single spoke cavity with beam apertureФ50 mm was proposed in the paper.This compact cavity may be a very promising option for CSNS linac upgrading.In addition to the optimization of the RF parameters,the multipacting behavior of the cavity is also studied,and cavity shape is optimized to reducevalue. | Yun Wang Huachang Liu Jianping Dai Peng Sha Ziwei Deng Bo Li Mengxu Fan Ahong Li Peihua Qu Xiaolei Wu Qiang Chen | 2019 | Radiation Detection Technology and Methods2019，3，3： | 0 |
| 16 | Multi-Objective Optimal Design of the Wind-Wave Hybrid Platform with the Coupling Interaction显示文摘An offshore wind-wave hybrid platform could consistently and cost-effectively supply renewable power.A multi-objective optimization process is proposed for a hybrid platform with hydrodynamic coupling interaction.The effects of various critical structural parameters,spacing values,and wave directions are studied for higher energy capture and offshore platform stability.Approximation models of various key parameters are established to optimize the hybrid system,with the objects of the power capture width ratio and the stability index of the platform.The optimization results are affected by the hydrodynamic coupling interaction,with a tendency to affect the higher frequency of hydrodynamic performance in the hybrid system.After the optimization,an appropriate spacing value effectively improves energy capture performance.The optimal array distance D_(Ff),D_(Fp),the optimal structural parameters R_(p),r_(p),d_(f),r_(f),and B_(PTO)are 11.57,12.75,5.1,3.3,1.5,6.5 m,and 80436 Nm s^(-1),respectively.The peak value of the wave energy converter capture width ratio in the hybrid system increases by almost 50%,with a 54%decrease in the stability index. | DENG Ziwei ZHANG Baocheng MIAO Yu ZHAO Bo WANG Qiang ZHANG Kaisheng | 2023 | Journal of Ocean University of China2023，22，5： | 0 |
| 17 | Microfluidic one-step, aqueous synthesis of size-tunable zeolitic imidazolate framework-8 for protein delivery显示文摘Zeolitic imidazolate framework-8(ZIF-8)with porous structure,biocompatibility,and pH-sensitive release behavior is a promising nanoplatform for protein delivery.However,it is still a challenging task for a practical synthesis of protein-loaded ZIF-8 nanoparticles.Here we report an all-aqueous microfluidic reactor for one-step,rapid,and highly controlled synthesis of ZIF-8 nanoparticles with high protein loading at room temperature.Microfluidic reactor allows for an ultrafast(<35 ms),complete mixing of Zn2+ions and 2-methylimidazole(2-MIM)at different molecular ratios,leading to the formation of stable ZIF-8 nanoparticles with tunable sizes(13.2–191.4 nm)in less than 30 s.By pre-mixing various proteins such as bovine serum albumin(BSA)(isoelectric point(pI)=5.82),ovalbumin(OVA)(pI=4.82),or RNase A(pI=8.93)with 2-MIM,ZIF-8 nanoparticles can be synthesized with protein encapsulation efficiency over 97%.Among the nanoparticles with different sizes,25 nm ZIF-8 nanoparticles show the best performance in promoting the cellular uptake of protein payload.Using OVA as a model protein,we demonstrate that 25 nm ZIF-8 nanoparticles significantly enhance the cytosolic delivery of antigen,as indicated by the effective activation of dendritic cells.We anticipate that this microfluidic synthesis of nanomaterials may advance the emerging field of cytosolic protein delivery. | Wenxing Lv Ziwei Han Shaokun Dong Yanjuan Huang Jinqi Deng Chao Liu Qiang Feng Jiashu Sun | 2023 | Nano Research2023，16，12： | 0 |
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