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| 1 | Cytokines,cytokine gene polymorphisms and Helicobacter pylori infection:Friend or foe?显示文摘Helicobacter pylori(H.pylori)is a flagellated,spiralshaped,microaerophilic Gram-negative bacillus that colonises the gastric mucosa of more than 50%of the human population.Infection is a risk factor for gastritis,ulcer disease and stomach cancer.Immunity against H.pylori is mainly related to Th1/Th17 skewing,and the activation of regulatory T cells is the main strategy used to limit inflammatory responses,which can result in the pathogen persistence and can lead to chronic gastrointestinal diseases,including cancer.Furthermore,host genetic factors that affect cytokines may determine differences in the susceptibility to many diseases.In this review,we present the cytokine profiles and the main cytokine gene polymorphisms associated with resistance/susceptibility to H.pylori and discuss how such polymorphisms may influence infection/disease outcomes. | Camila A Figueiredo Cintia Rodrigues Marques Ryan dos Santos Costa Hugo Bernardino F da Silva Neuza M Alcantara-Neves | 2014 | World Journal of Gastroenterology2014，20，18： | 11 |
| 2 | Different risk factors influence peptic ulcer disease development in a Brazilian population显示文摘AIM: To investigate age, sex, histopathology and Helicobacter pylori (H. pylori) status, as risk factors for gastroduodenal disease outcome in Brazilian dyspeptic patients.tients submitted to upper gastroscopy at Hospital das Clinicas of Marilia, antral biopsy specimens were obtained and subjected to histopathology and H. pylori diagnosis. All patients presenting chronic gastritis (CG) and peptic ulcer (PU) disease localized in the stomach, gastric ulcer (GU) and/or duodenal ulcer (DU) were included in the study. Gastric biopsies (n = 668) positive for H. pylori by rapid urease test were investigated for vacuolating cytotoxin A (vacA ) medium (m) region mosaicism by polymerase chain reaction. Logistic regression analysis was performed to verify the association of age, sex, histopathologic alterations, H. pylori diagnosis and vacA m region mosaicism with the incidence of DU, GU and CG in patients. RESULTS: Of 1466 patients submitted to endoscopy, 1060 (72.3%) presented CG [male/female = 506/554; mean age (year) ± SD = 51.2 ± 17.81], 88 (6.0%) presented DU [male/female = 54/34; mean age (year) ± SD = 51.4 ± 17.14], and 75 (5.1%) presented GU [male/female = 54/21; mean age (year) ± SD = 51.3 ± 17.12] and were included in the comparative analysis. Sex and age showed no detectable effect on CG incidence (overall c 2 = 2.1, P = 0.3423). Sex [Odds ratios (OR) = 1.8631, P = 0.0058] but not age (OR = 0.9929, P = 0.2699) was associated with DU and both parameters had a highly significant effect on GU (overall c 2 = 30.5, P < 0.0001). The histopathological results showed a significant contribution of ageing for both atrophy (OR = 1.0297, P < 0.0001) and intestinal metaplasia (OR = 1.0520, P < 0.0001). Presence of H. pylori was significantly associated with decreasing age (OR = 0.9827, P < 0.0001) and with the incidence of DU (OR = 3.6077, P < 0.0001). The prevalence of m1 in DU was statistically significant (OR = 2.3563, P = 0.0018) but not in CG (OR = 2.678, P = 0.0863) and GU (OR = 1.520, P = 0.2863). CONCLUSION: In our population, male gender was a risk factor for PU; ageing for GU, atrophy and metapla-sia; and H. pylori of vacA m1 genotype for DU. | Rodrigo Buzinaro Suzuki Rodrigo Faria Cola Larissa Tranquilino Bardela Cola Camila Garcia Ferrari Fred Ellinger Altino Luiz Therezo Luis Carlos da Silva André Eterovic Márcia Aparecida Sperana | 2012 | World Journal of Gastroenterology2012，18，38： | 8 |
| 3 | Altered blood-brain barrier permeability in rats with prehepatic portal hypertension turns to normal when portal pressure is lowered显示文摘AIM: To study the blood-brain barrier integrity in prehe-patic portal hypertensive rats induced by partial portal vein ligation, at 14 and 40 d after ligation when portal pressure is spontaneously normalized. METHODS: Adult male Wistar rats were divided into four groups: GroupⅠ: Sham14d, sham operated; GroupⅡ: PH14d, portal vein stenosis; (both groups were used 14 days after surgery); GroupⅢ: Sham40d, Sham operated and GroupⅣ: PH40d Portal vein stenosis (GroupsⅡandⅣused 40 d after surgery). Plasma ammonia, plasma and cerebrospinal fluid protein and liver enzymes concentrations were determined. Trypan and Evans blue dyes, systemically injected, were investigated in hippocampus to study blood-brain barrier integrity. Portal pressure was periodically recorded. RESULTS: Forty days after stricture, portal pressure was normalized, plasma ammonia was moderately high, and both dyes were absent in central nervous system parenchyma. All other parameters were reestablished. When portal pressure was normalized and ammonia level was lowered, but not normal, the altered integrity of blood-brain barrier becomes reestablished. CONCLUSION: The impairment of blood-brain barrier and subsequent normalization could be a mechanism involved in hepatic encephalopathy reversibility, Hemo-dynamic changes and ammonia could trigger blood-brain barrier alterations and its reestablishment. | Francisco Eizayaga Camila Scorticati Juan P Prestifilippo Salvador Romay Maria A Fernandez José L Castro Abraham Lemberg Juan C Perazzo | 2006 | World Journal of Gastroenterology2006，12，9： | 3 |
| 4 | Inhibitory Action of Aqueous Coffee Ground Extracts on the Corrosion of Carbon Steel in HCl Solution显示文摘 | VANESSA V T ROBERTO S A CAMILA F de S | | 0，，07： | 1 |
| 5 | Effect of the treatment with achyrocline satureioides (free and nanocapsules essential oil) and diminazene aceturate on hematological and biochemical parameters in rats infected by trypanosoma evansi显示文摘 | Guilherme M. Do Carmo Matheus D. Baldissera Rodrigo A. Vaucher Virginia Cielo Rech Camila B. Oliveira Michele Rorato Sagrillo Aline A. Boligon Margareth L. Athayde Marta P. Alves Raqueli T. Fran?a Sonia T.A. Lopes Claiton I. Schwertz Ricardo E. Mendes Sil | 2014 | Experimental Parasitology2014，，： | 1 |
| 6 | Natural rubber-clay nanocomposites: Mechanical and structural properties 显示文摘 | Camila A Rezende Fabio C Braganca Telma R Doi | 2010 | Polymer2010，51，16： | 1 |
| 7 | Efficacy of Gluma desensitizer on dentin hypersensitivity in periodontally treated patients 显示文摘 | Camila de Assis Cde A Antoniazzi RP Zanatta FB | 2006 | Braz Oral Res2006，20，3： | 1 |
| 8 | ^sup 18^F-FDG PET After 2 Cycles of ABVD Predicts Event-Free Survival in Early and Advanced Hodgkin Lymphoma显示文摘 | Cerci Juliano J Pracchia Luís F Linardi Camila C G Pitella Felipe A Delbeke Dominique Izaki Marisa Trindade Evelinda Junior José Soares Buccheri Valeria Meneghetti José C | 2010 | The Journal of Nuclear Medicine2010，，： | 1 |
| 9 | Direct trajectory optimization and costate estimation of finite horizon and infinite horizon optimal control problems via a radau pseudospectral method显示文摘 | Divya G Michael A P Camila F | 2009 | Computational Optimization and Applications2009，49，2： | 1 |
| 10 | Inhibitory action of aqueous coffee ground extracts on the corrosion of carbon steel in HCI solution 显示文摘 | VANESSA V T ROBERTO S A CAMILA F TATIANA L F CARLOS R ALEXANDRE G T ELIANE D | 2011 | Corrosion Science2011，53，： | 1 |
| 11 | Production of structured lipids by acidolysis with immobilized Rhizomucor miehei lipases: Selection of suitable reaction conditions显示文摘 | Camila A. Palla Consuelo Pacheco María E. Carrín | 2011 | B, Enzymatic2011，，： | 1 |
| 12 | Natural rubber-clay nanocomposites:mechanical and structural properties显示文摘 | CAMILA A REZENDE F C BRAGANCA T R | 2010 | Polymer2010，4，： | 1 |
| 13 | Action of sisal (Agave sisalana, Perrine) extract in the in vitro development of sheep and goat gastrointestinal nematodes显示文摘 | ROBERTA X S CAROLINA S C MARIANA B B MARIA J M LUCIANA M K CAMILA 0 C CLAUDIA M L ALEXSANDRO B ELANE A A SIMONE L B MARIA A O | 2012 | Experimental Parasitology2012，13，： | 1 |
| 14 | Numerical and experimental ana- lysis of the heat and mass transfer during olafa显示文摘 | Camila A P Viviana C M | 2012 | Appl Therm Eng2012，48，： | 1 |
| 15 | Prognostic value of computed tomographic pulmonary angiography and the pulmonary embolism severity index in patients with acute pulmonary embolism显示文摘 | Thiago Horta Soares Marcos de Bastos Bruna Vila?a de Carvalho Wanderval Moreira Cristiane Pena Cabral Luciano Fagundes de Paula Camila Caram Suely Meireles Rezende | 2013 | Blood Coagulation & Fibrinolysis2013，，1： | 1 |
| 16 | Production of structured lipids by aeidolysis with immobilized Rhizomucor miehei lipases: Selection of suitable reaction conditions显示文摘 | Camila A Palla Consuelo Pacheco Maria E Carrin | 2012 | Journal of Molecular Catalysis B: Enzymatic2012，76，： | 1 |
| 17 | Serum levels of LH, FSH, estradiol and progesterone in female rats experimentally infected by Trypanosoma evansi显示文摘 | Luciana Faccio Aleksandro S. Da Silva Alexandre A. Tonin Raqueli T. Fran?a Lucas T. Gressler Maíra M. Copetti Camila B. Oliveira Manuela B. Sangoi Rafael N. Moresco Nathieli B. Bottari Marta M.M.F. Duarte Silvia G. Monteiro | 2013 | Experimental Parasitology2013，，1： | 1 |
| 18 | SSEA-4 identifies mesenchymal stem cells from bone marrow 显示文摘 | Eun J Darko B Camila A | 2007 | Blood2007，109，4： | 1 |
| 19 | Surface esterifi- cation of cellulose nanofibers by a simple organocatalytic me- thodology显示文摘 | Jhon A A R Camila J S Patricia C | 2014 | Carbohydr Polym2014，114，： | 1 |
| 20 | Exercise and Mental Health: Many Reasons to Move显示文摘 | Deslandes Andréa Moraes Helena Ferreira Camila Veiga Heloisa Silveira Heitor Mouta Raphael Pompeu Fernando A M S Coutinho Evandro Silva Freire Laks Jerson | 2009 | Neuropsychobiology2009，，： | 1 |
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