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| 1 | Genetic diversity of rice cultivars (Oryza sativa L.) in China and the temporal trends in recent fifty years显示文摘To understand geographical distribution of the genetic diversity of rice cultivars {Oryza sativa L.) and its trends in recent fifty years in China, 453 ’ accessions were analyzed by 36 microsatellites loci and 42 phenotypic traits. Results revealed that the genetic diversity by SSRs is highly consistent with that by phenotypic traits and the genetic diversity of indica cultivars was higher than that of japonica cultivars; the genetic diversity of cultivars declined from 1950s to 1980s and then increased greatly; among the six rice ecological zones (REZs), genetic diversity of REZTl was the highest and those of REZV and REZVT were the lowest at both DNA and phenotypic level. Jiangsu and Jiangxi provinces in the middle and lower reaches of Yangtze River and Sichuan province in southwest of China were the areas with the highest genetic diversity. Breeders in REZV which is an important japonica rice area but with very low genetic diversity should explore more gene resources to widen the genetic backgrounds of cultivars. | QI Yonawen ZHANG Dongling ZHANG Hongliang WANG Meixing SUN Junli WEI Xinghua QIU Zongen TANG Shengxiang CAO Yongsheng WANG Xiangkun LI Zichao | 2006 | Chinese Science Bulletin2006，51，6： | 27 |
| 2 | Natural Variation in CCD4 Promoter Underpins Species-Specific Evolution of Red Coloration in Citrus Peel显示文摘Carotenoids and apocarotenoids act as phytohormones and volatile precursors that influence plant development and confer aesthetic and nutritional value critical to consumer preference.Citrus fruits display considerable natural variation in carotenoid and apocarotenoid pigments.In this study,using an integrated genetic approach we revealed that a 5;c/s-regulatory change at CCD4b encoding CAROTENOID CLEAVAGE DIOXYGENASE 4b is a major genetic determinant of natural variation in C3 0 apocarotenoids responsible for red coloration of citrus peel.Functional analyses demonstrated that in addition the known role in synthesizing 3-citraurin,CCD4b is also responsible for the production of another important C3 0 apocarotenoid pigment,p-citraurinene.Furthermore,analyses of the CCD4b promoter and transcripts from various citrus germplasm accessions established a tight correlation between the presence of a putative 5'c/s-regulatory enhancer within an MITE transposon and the enhanced allelic expression of CCD4b in C3 0 apocarotenoid-rich red-peeled accessions.Phylogenetic analysis provided further evidence that functional diversification of CCD4b and naturally occurring variation of the CCD4b promoter resulted in the stepwise evolution of red peels in mandarins and their hybrids.Taken together,our findings provide new insights into the genetic and evolutionary basis of apocarotenoid diversity in plants,and would facilitate breeding efforts that aim to improve the nutritional and aesthetic value of citrus and perhaps other fruit crops. | Xiongjie Zheng Kaijie Zhu Quan Sun Weiyi Zhang Xia Wang Hongbo Cao Meilian Tan Zongzhou Xie Yunliu Zeng Junli Ye Lijun Chai Qiang Xu Zhiyong Pan Shunyuan Xiao Paul D.Fraser Xiuxin Deng | 2019 | Molecular Plant2019，12，9： | 18 |
| 3 | Transcriptomics-based identification of WRKY genes and characterization of a salt and hormone-responsive PgWRKY1 gene in Panax ginseng显示文摘WRKY 蛋白质属于一个抄写因素(TF ) 家庭和戏在许多植物过程,对不能生活、关於生命的压力的包括的植物回答,以及第二等的新陈代谢的动态角色。然而,在人参属人参 C ·迈耶的 WRKY 基因都没迄今为止被报导。在这研究,从甲基 jasmonate (MeJA ) 的很多 WRKY unigenes 对待偶然这种的根 transcriptome 用下一代的定序被识别技术。编码 WRKY 蛋白质的 48 有希望的 WRKY unigenes 的一个总数被消除冤屈和不完全的开的读物框架(ORF ) 获得。种系发生的分析揭示 48 WRKY TF,包括 11 组我, 36 组 II,和 1 组 III。而且,指定为 PgWRKY1 的一 MeJA 应答的 unigene 被克隆并且描绘。它包含 1077 bp 的全部 ORF 并且编码 358 氨基酸残余的多肽。PgWRKY1 蛋白质包含由保存氨基酸顺序主题 WRKYGQK 和 C 2 H 2-type 锌手指主题属于 WRKY 亚群 II-d。在洋葱和烟草外皮房间的 PgWRKY1-GFP 熔化蛋白质的 Subcellular 本地化表明 PgWRKY1 在原子核是只在场的。量的即时聚合酶链反应分析证明 PgWRKY1 的表示与叶子,茎,和种子相比在根和侧面的根是相对更高的。重要地, PgWRKY1 表示被水杨酸显著地导致酸, abscisic 酸,和 NaCl,而是由 MeJA 处理的 downregulated。这些结果建议 PgWRKY1 可能是对荷尔蒙和盐压力作出回应的多重压力可诱导的基因。 | Mohammed Nuruzzaman Hongzhe Cao Hao Xiu Tiao Luo Jijia Li Xianghui Chen Junli Luo Zhiyong Luo | 2016 | Acta Biochimica et Biophysica Sinica2016，48，2： | 12 |
| 4 | Differential effects of controlled hypotension on gastric intramucosal pH and post-operational gastrointestinal functional under two different anesthesia methods显示文摘Objective:To observe the effects of controlled hypotension on gastric intramucosal pH and post-operational gastrointestinal functions using two specific anesthesia methods.Methods:Thirty patients(ASAⅡ)scheduled for ectomy of hepatocarcinoma,were randomly assigned to two groups:epidural block combined with intravenous anesthesia group(E group)and inhalation anesthesia group(G group).Gastric PgCO2 and pHi were monitored at different time points,before theintravenous induction of controlled hypotension,after 1 h and2 h,and 1 h after the termination of controlled hypotension.In the meanwhile,the artery blood gas was analyzed.Results:There was no significant difference in blood gas indexes between E group and G group.However,pHi decreased significantly after 1 h and 2 h of controlled hypotension(P <0.05),and during the same periods PgCO2 increased significantly(P <0.05 or P <0.01),the time of bowelm ovement and defecating deferred significantly shorter in G group patients,when compared with E group patients.Conclusion:Epidural block in combination with general anesthesia can improve gastrointestinal blood flow during controlled hypotension and facilitates post-operational recovery of gastrointestinal functions. | Guanglei Wang Junli Cao Gongjian Liu | 2008 | Journal of Nanjing Medical University2008，22，1： | 7 |
| 5 | Genetic structure and diversity of Oryza sativa L. in Guizhou,China显示文摘Preserving many kinds of rice resources and rich variations, Guizhou Province is one of the districts with the highest genetic diversity of cultivated rice (Oryza sativa L.) in China. In the current research, genetic diversity and structure of 537 accessions of cultivated rice from Guizhou were studied using 36 microsatellite markers and 39 phenotypic characters. The results showed that the model-based genetic structure was the same as genetic-distance-based one using SSRs but somewhat different from the documented classification (mainly based on phenotype) of two subspecies. The accessions being classified into indica by phenotype but japonica by genetic structure were much more than that being classified into japonica by phenotype but indica by genetic structure. Like Ding Ying’s taxonomic sys- tem of cultivated rice, the subspecific differentiation was the most distinct differentiation within culti- vated rice. But the differentiation within indica or japonica population was different: japonica presented clearer differentiation between soil-watery ecotypes than indica, and indica presented clearer differen- tiation between seasonal ecotypes than japonica. Cultivated rices in Guizhou revealed high genetic diversity at both DNA and phenotypic levels. Possessing the highest genetic diversity and all the nec- essary conditions as a center of genetic diversity, region Southwestern of Guizhou was suggested as the center of genetic diversity of O. sativa L. from Guizhou. | ZHANG DongLing ZHANG HongLiang WEI XingHua QI YongWen WANG Meixing SUN JunLi DING Li TANG ShengXiang QIU Zong'En CAO YongSheng WANG XiangKun LI ZiChao | 2007 | Chinese Science Bulletin2007，52，3： | 5 |
| 6 | Effect of Nitrogen Fertilizer on the Accumulation and Distribution of Dry Matter in Broomcorn Millet显示文摘[Objective] To understand the effect of nitrogen application on dry matter accumulation and allocation dynamics in broomcorn millet. [Method] The accumulation and distribution of dry matter were studied using cultivars Jin Shu 7 and Huang Mizi at different levels of nitrogen fertilizer at the jointing stage. [Result] The results showed that increasing N application led to the increase of green leaf area and the delay of leaf senescence, which was beneficial to the accumulation of dry matter.Appropriate nitrogen application(90 kg/hm2) could coordinate the translocation rate of dry matter among different plant parts, thereby enhancing the yield of broomcorn millet; among different organs, the contribution rate of stem to kernel was greater than that of leaf to kernel; there was obvious correlation between dry matter and yield. For Jin Shu 7, leaf area and dry weight of spike showed significant negative correlation with yield. [Conclusion] The formation of grain yield of broomcorn millet involved the accumulation and allocation of dry matter, the appropriate amount of nitrogen application(90 kg/hm2) could improve the rates of translocation and contribution of dry matter, thereby promoting the yield of broomcorn millet. | Ling CHEN Zhijun QIAO Junjie WANG Haigang WANG Xiaoning CAO Junli DONG | 2015 | Agricultural Science & Technology2015，16，7： | 4 |
| 7 | Glaucocalyxin A, a negative Akt regulator, specifically induces apoptosis in human brain glioblastoma U87MG cells显示文摘Akt 在反肿瘤代理人的发展正在成为一个吸引人的目标。在现在的学习,我们试图对恶意的 glioma 发现新奇否定 Akt 管理者。屏蔽站台在一根 Akt-GFP overexpression 房间线执行了的一个 Akt 管理者被开发,并且自然产品图书馆被屏蔽并且评估了使用这个平台。另外,管理者的细胞毒素的效果被 MTT 试金检测。房间 apoptosis 是由 Hoechst 33342 染色和流动 cytometry 分析的 assayed。以后,表明小径的 apoptotic 被西方的污点分析调查。Glaucocalyxin A,从 Rabdosia 孤立装饰用的梨树,作为一个有势力被识别 Akt 的否定管理者。在导出人的恶意的 glioma U87MG 房间, glaucocalyxin A 禁止了 Akt phosphorylation,压制了增长,并且支持了以一种剂量依赖者方式,然而并非在正常 glial 房间的 apoptosis。而且, glaucocalyxin A 激活 caspase-3,减少的坏 phosphorylation,并且减少了 apoptosis 的 X 连接禁止者的表示蛋白质。一起拿,这些结果显示 glaucocalyxin A 可以在恶意的 glioma 的处理成为一个有希望的候选人。 | Xian Xiao Weidong Cao Xiaofan Jiang Wei Zhang Yongqiang Zhang Bolin Liu Jinxiang Cheng Huiyong Huang Junli Huo Xiang Zhang | 2013 | Acta Biochimica et Biophysica Sinica2013，45，11： | 2 |
| 8 | Effects of tide-surge interactions on storm surges along the coast of the Bohai Sea, Yellow Sea, and East China Sea显示文摘A two-dimensional coupled tide-surge model was used to investigate the effects of tide-surge interactions on storm surges along the coast of the Bohai Sea, Yellow Sea, and East China Sea. In order to estimate the impacts of tide-surge interactions on storm surge elevations, Typhoon 7203 was assumed to arrive at 12 different times, with all other conditions remaining constant. This allowed simulation of tide and total water levels for 12 separate cases. Numerical simulation results for Yingkou, Huludao, Shijiusuo, and Lianyungang tidal stations were analyzed. Model results showed wide variations in storm surge elevations across the 12 cases. The largest difference between 12 extreme storm surge elevation values was of up to 58 cm and occurred at Yingkou tidal station. The results indicate that the effects of tide-surge interactions on storm surge elevations are very significant. It is therefore essential that these are taken into account when predicting storm surge elevations. | XU JunLi ZHANG YuHong CAO AnZhou LIU Qiang LV XianQing | 2016 | Science China Earth Sciences2016，59，6： | 2 |
| 9 | Structural variation and parallel evolution of apomixis in citrus during domestication and diversification显示文摘Apomixis,or asexual seed formation,is prevalent in Citrinae via a mechanism termed nucellar or adventitious embryony.Here,multiple embryos of a maternal genotype form directly from nucellar cells in the ovule and can outcompete the developing zygotic embryo as they utilize the sexually derived endosperm for growth.Whilst nucellar embryony enables the propagation of clonal plants of maternal genetic constitution,it is also a barrier to effective breeding through hybridization.To address the genetics and evolution of apomixis in Citrinae,a chromosome-level genome of the Hongkong kumquat(Fortunella hindsii)was assembled following a genome-wide variation map including structural variants(SVs)based on 234 Citrinae accessions.This map revealed that hybrid citrus cultivars shelter genome-wide deleterious mutations and SVs into heterozygous states free from recessive selection,which may explain the capability of nucellar embryony in most cultivars during Citrinae diversification.Analyses revealed that parallel evolution may explain the repeated origin of apomixis in different genera of Citrinae.Within Fortunella,we found that apomixis of some varieties originated via introgression.In apomictic Fortunella,the locus associated with apomixis contains the FhRWP gene,encoding an RWP-RK domain-containing protein previously shown to be required for nucellar embryogenesis in Citrus.We found the heterozygous SV in the FhRWP and CitRWP promoters from apomictic Citrus and Fortunella,due to either two or three miniature inverted transposon element(MITE)insertions.A transcription factor,FhARID,encoding an AT-rich interaction domain-containing protein binds to the MITEs in the promoter of apomictic varieties,which facilitates induction of nucellar embryogenesis.This study provides evolutionary genomic and molecular insights into apomixis in Citrinae and has potential ramifications for citrus breeding. | Nan Wang Xietian Song Junli Ye Siqi Zhang Zhen Cao Chenqiao Zhu Jianbing Hu Yin Zhou Yue Huang Shuo Cao Zhongjie Liu Xiaomeng Wu Lijun Chai Wenwu Guo Qiang Xu Brandon S.Gaut Anna M.G.Koltunow Yongfeng Zhou Xiuxin Deng | 2022 | National Science Review2022，9，10： | 1 |
| 10 | Glimepiride induces proliferation and differentiation of rat osteoblasts via the PI3-kinase/Akt pathway显示文摘 | Pan Ma Bin Gu Junli Ma Lingling E Xia Wu Junkai Cao Hongchen Liu | 2010 | Metabolism2010，，3： | 1 |
| 11 | Genetic Architecture and Functional Implications of the CSF‑Contacting Nucleus显示文摘We previously identified a unique nucleus,the cerebrospinal fluid(CSF)-contacting nucleus.This study aims to understand its gene architecture and preliminarily suggest its functions.The results showed that there were about 19,666 genes in this nucleus,of which 913 were distinct from the dorsal raphe nucleus(non-CSF contacting).The top 40 highly-expressed genes are mainly related to energy metabolism,protein synthesis,transport,secretion,and hydrolysis.The main neurotransmitter is 5-HT.The receptors of 5-HT and GABA are abundant.The channels for Cl–,Na+,K+,and Ca2+are routinely expressed.The signaling molecules associated with the CaMK,JAK,and MAPK pathways were identified accurately.In particular,the channels of transient receptor potential associated with nociceptors and the solute carrier superfamily members associated with cell membrane transport were significantly expressed.The relationship between the main genes of the nucleus and life activities is preliminarily verified. | Siyuan Song Yumin Yuan Lingling Xu Jun Jiang Ying Li Yao Yan Qing Li Fang Zhou Junli Cao Licai Zhang | 2023 | Neuroscience Bulletin2023，39，11： | 1 |
| 12 | Aging Resistance Evaluation of Aged Paper Reinforced with Different Nanocelluloses显示文摘Paper documents experience severe acidification and embrittlement.Nanocellulose is an excellent reinforcement material for paper documents owing to its compatibility and excellent mechanical strength.However,little research has been conducted on the aging resistance of nanocellulose-reinforced paper.In this study,six types of nanocelluloses were used to reinforce aged paper.The reinforcement and anti-aging performances were evaluated,and the anti-aging mechanism was further clarified.Nanocellulose with a high degree of polymerization can better enhance aged paper,and non-chemical nanocellulose also shows better anti-aging performance,such as nanocellulose prepared by mechanical or biological methods.However,nanocellulose prepared using chemical methods exhibits poor reinforcement and anti-aging performance.This is because it has a small particle size that is not beneficial for physical crosslinking with paper fibers.More importantly,the introduction of acidic or oxidizing groups on nanocellulose accelerates the acid hydrolysis and oxidation rate of paper fibers,especially nanocellulose prepared by 2,2,6,6-tetramethylpiperidine-1-oxyl oxidation,which should not be used to protect paper documents. | Xian Cao Bei He Jianlin Wang Chunhui Zhang Donglin Tang Qingyou Liang Chuanfu Liu Huiming Fan Junli Ren | 2023 | Paper And Biomaterials2023，8，3： | 0 |
| 13 | Robust,flame-retardant and colorful superamphiphobic aramid fabrics for extreme conditions显示文摘High-performance superamphiphobic fabrics are very useful in special fields,such as firefighting,rescue,and polar sports.The complicated preparation process,easily damaged surface structure,and high cost drastically limit their commercial application.In this work,we utilized a simple,low-cost superamphiphobic coating to prepare a superamphiphobic aramid fabric(SAF).The excellent repellency to acid/alkali solutions and low boiling point organic solvents has been demonstrated with the contact angle of>150°and>130°,respectively.Additionally,the original color of the fabric can also be maintained,accompanied by superior flame retardancy,strength and comfort with thermal degradation of 361℃.More importantly,SAF displayed excellent durability via 50 standard machine washes,100-min of ultrasonic washing,10-min of UV irradiation,120-min of high-temperature heating,5000 cycles of abrasion,and destructive abrasion by sharp metal.All the results showed the superior performance of our SAF in protective fabrics under extreme environmental conditions. | LIU Xiang CHEN JunLi SHAO QingQing CAO JiQiang DU ZhaoQun LIU HongLing YU WeiDong | 2021 | Science China(Technological Sciences)2021，64，8： | 0 |
| 14 | Highly pathogenic coronavirus N protein aggravates inflammation by MASP-2-mediated lectin complement pathway overactivation显示文摘Excessive inflammatory responses contribute to the pathogenesis and lethality of highly pathogenic human coronaviruses,but the underlying mechanism remains unclear.In this study,the N proteins of highly pathogenic human coronaviruses,including severe acute respiratory syndrome coronavirus(SARS-CoV),middle east respiratory syndrome coronavirus(MERS-CoV)and severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),were found to bind MASP-2,a key serine protease in the lectin pathway of complement activation,resulting in excessive complement activation by potentiating MBL-dependent MASP-2 activation,and the deposition of MASP-2,C4b,activated C3 and C5b-9.Aggravated inflammatory lung injury was observed in mice infected with adenovirus expressing the N protein.Complement hyperactivation was also observed in SARS-CoV-2-infected patients.Either blocking the N protein:MASP-2 interaction,MASP-2 depletion or suppressing complement activation can significantly alleviate N protein-induced complement hyperactivation and lung injury in vitro and in vivo.Altogether,these data suggested that complement suppression may represent a novel therapeutic approach for pneumonia induced by these highly pathogenic coronaviruses. | Ting Gao Lin Zhu Hainan Liu Xiaopeng Zhang Tingting Wang Yangbo Fu Hongzhen Li Qincai Dong Yong Hu Zhang Zhang Jing Jin Zijing Liu Weihong Yang Yaoning Liu Yanwen Jin Kaitong Li Yongjiu Xiao Junli Liu Huailong Zhao Yue Liu Ping Li Jibo Song Lu Zhang Yuwei Gao Sisi Kang Shoudeng Chen Qingjun Ma Xiuwu Bian Wei Chen Xuan Liu Qing Mao Cheng Cao | 2022 | Signal Transduction and Targeted Therapy2022，7，10： | 0 |
| 15 | In memoriam Professor Wei Jiang, one of the young editorial board members显示文摘It is with great sadness for us that Professor Wei Jiang, a young and well-known supramolecular chemist, passed away on Sunday25 December 2022. He created a series of supramolecular hosts including Oxatubarenes [1] and Naphthotubes [2] with inner functionalized groups [3–6] and applied them into materials, catalysis,molecular machines and drug recognition and delivery fields [7–10] during his independent research career. | Qiang Shi Liping Cao Yong Chen Huanfang Guo Yu Liu Tao Tu Feng Wang Junli Wang Leyong Wang Yongshu Xie Cheng Yang Xin Zhao | 2023 | Chinese Chemical Letters2023，34，4： | 0 |
| 16 | Discovery and nomenclature of nucleus that regulate cerebrospinal fluid显示文摘The difference of composition in extracellular fluid in brain parenchyma and CSF suggests that CSF-brain barrier(CBB)is objective,which is necessary to maintain the stability of their internal environment.However,the information exchange between brain and CSF is also objective.For example,CSF is changes during diseases,the application of drugs(such as lumbar anesthesia)or tissue transplantation via the CSF pathway may also produce central(cerebral)effects.Who breaks through the barrier and mediates brain-CSF communication?Since 1992,we have found that the peripheral nerve tracer CB-HRP injected into the lateral ventricle of mice,rats and macaques is blocked in the ventricle wall and can only run in CSF,but a large number of CB-HRP-positive labeled neurons can be seen in specific parts of the brain stem parenchyma.Understandably,these neurons touch markers in CSF.Otherwise,they cannot be tagged. | Zhang Licai Song Siyuan Lu Xianfu Zhou Fang Liu He Cao Junli | 2021 | 解剖学杂志2021，44，S01： | 0 |
| 17 | Impacts of Suburbanization on Urban Eco-environment of Xi'an in China显示文摘Suburbanization in large cities is an important phenomenon in the process of urbanization development in China in recent decades,which plays a very important role in promoting city development,whereas some side effects on the eco-environment appeared at the same time.This paper,taking Xi'an City in China as a case study site,analyzed the features of population suburbanization and industry suburbanization and pointed out the impacts of suburbanization on urban eco-environment.Based on the research,suggestions of countermeasures for urban planning and municipal management of Xi'an City in protecting urban eco-environment and conserving natural ecology were put forward in the end. | Li Junli Cao Mingming | 2011 | Chinese Journal of Population,Resources and Environment2011，9，4： | 0 |
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