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| 1 | H7N9 virulent mutants detected in chickens in China pose an increased threat to humans显示文摘 | Jianzhong Shi Guohua Deng Huihui Kong Chunyang Gu Shujie Ma Xin Yin Xianying Zeng Pengfei Cui Yan Chen Huanliang Yang Xiaopeng Wan Xiurong Wang Liling Liu Pucheng Chen Yongping Jiang Jinxiong Liu Yuntao Guan Yasuo Suzuki Mei Li Zhiyuan Qu Lizheng Guan Jinkai Zang Wenli Gu Shuyu Han Yangming Song Yuzhen Hu Zeng Wang Linlin Gu Wenyu Yang Libin Liang Hongmei Bao Guobin Tian Yanbing Li Chuanling Qiao Li Jiang Chengjun Li Zhigao Bu Hualan Chen | 2017 | Cell Research2017，27，12： | 70 |
| 2 | A seven-gene-deleted African swine fever virus is safe and effective as a live attenuated vaccine in pigs显示文摘African swine fever(ASF)is a devastating infectious disease in swine that is severely threatening the global pig industry.An efficacious vaccine is urgently required.Here,we used the Chinese ASFV HLJ/18 as a backbone and generated a series of genedeleted viruses.The virulence,immunogenicity,safety,and protective efficacy evaluation in specific-pathogen-free pigs,commercial pigs,and pregnant sows indicated that one virus,namely HLJ/18-7GD,which has seven genes deleted,is fully attenuated in pigs,cannot convert to the virulent strain,and provides complete protection of pigs against lethal ASFV challenge.Our study shows that HLJ/-18-7GD is a safe and effective vaccine against ASFV,and as such is expected to play an important role in controlling the spread of ASFV. | Weiye Chen Dongming Zhao Xijun He Renqiang Liu Zilong Wang Xianfeng Zhang Fang Li Dan Shan Hefeng Chen Jiwen Zhang Lulu Wang Zhiyuan Wen Xijun Wang Yuntao Guan Jinxiong Liu Zhigao Bu | 2020 | Science China(Life Sciences)2020，63，5： | 72 |
| 3 | Electrochemical behavior of zirconium in molten NaCl-KCl-K_2ZrF_6 system显示文摘The electrochemical reduction of Zr4+(complex) ions in NaCl-KCl-K2ZrF6 molten salt on Pt electrode was investigated using cyclic voltammetry and square wave voltammetry at 1023 K.Two cathodic reduction peaks related to Zr4+/Zr2+ and Zr2+/Zr steps were observed in the cyclic voltammograms.The result was also confirmed by square wave voltammetry.The diffusion coefficient of Zr4+(complex) ions at 1023 K in NaCl-KCl-K2ZrF6 melt,measured by cyclic voltammetry,is about 4.22×10-6 cm2/s.The characterization of the deposits obtained by potentiostatic electrolysis at different potentials was investigated by XRD,and the results were well consistent with the electrochemical reduction mechanism of Zr4+(complex) ions. | WU Yanke XU Zhigao CHEN Song WANG Lijun LI Guoxun | 2011 | Rare Metals2011，30，1： | 16 |
| 4 | TRIM35 mediates protection against influenza infection by activating TRAF3 and degrading viral PB2显示文摘Tripartite motif(TRIM)family proteins are important effectors of innate immunity against viral infections.Here we identified TRIM35 as a regulator of TRAF3 activation.Deficiency in or inhibition of TRIM35 suppressed the production of type I interferon(IFN)in response to viral infection.777m35-deficient mice were more susceptible to influenza A virus(IAV)infection than were wild-type mice.TRIM35 promoted the RIG-Imediated signaling by catalyzing Lys63-linked polyubiquitination of TRAF3 and the subsequent formation of a signaling complex with VISA and TBK1.IAV PB2 polymerase countered the innate antiviral immune response by impeding the Lys63-linked polyubiquitination and activation of TRAF3.TRIM35 mediated Lys48-linked polyubiquitination and proteasomal degradation of IAV PB2,thereby antagonizing its suppression of TRAF3 activation.Our in vitro and in vivo findings thus reveal novel roles of TRIM35,through catalyzing Lys63-or Lys48-linked polyubiquitination,in RIG-I antiviral immunity and mechanism of defense against IAV infection. | Nan Sun Li Jiang Miaomiao Ye Yihan Wang Guangwen Wang Xiaopeng Wan Yuhui Zhao Xia Wen Libin Liang Shujie Ma Liling Liu Zhigao Bu Hualan Chen Chengjun Li | 2020 | Protein & Cell2020，11，12： | 4 |
| 5 | Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase显示文摘 | Liming Sun Huayi Wang Zhigao Wang Sudan He She Chen Daohong Liao Lai Wang Jiacong Yan Weilong Liu Xiaoguang Lei Xiaodong Wang | 2012 | Cell2012，，1： | 2 |
| 6 | High-efficiency ultra-thin Cu_(2)ZnSnS_(4) solar cells by double-pressure sputtering with spark plasma sintered quaternary target显示文摘In recent years,Cu_(2)ZnSnS_(4)(CZTS)semiconductor materials have received intensive attention in the field of thin-film solar cells owing to its non-toxic and low-cost elements.In this work,double-pressure sputtering technology is applied to obtain highly efficient and ultra-thin(-450 nm)pure Cu_(2)ZnSnS_(4)(CZTS)solar cell.Using mixed materials with sulfides and copper powder as a quaternary target via spark plasma sintering(SPS)method and adopting double-layer sputtering(high+low pressure),a highly adhesive and large-grained CZTS thin film is achieved.As a result,the damage to the surface of Mo contact is decreased so that the reflectivity of incident light can be improved.Moreover,the composition of CZTS film was more uniform and the secondary phase separation at the Mo interface was reduced.Therefore,the interface defect state and deep level defect density in corresponding device with double-pressure is reduced and the ratio of depletion thickness to absorption layer thickness can reached to 0.58,which promoted the collection of photogenerated carriers.Finally,an efficiency of 9.3%for ultra-thin(~450 nm)CZTS film solar cell is obtained. | Ping Fan Zhigao Xie Guangxing Liang Muhammad Ishaq Shuo Chen Zhuanghao Zheng Chang Yan Jialiang Huang Xiaojing Hao Yi Zhang Zhenghua Su | 2021 | Journal of Energy Chemistry2021，30，10： | 2 |
| 7 | Magnetic phase transition and size effect in thin magnetic film 显示文摘 | Huang Zhigao Chen Zhigao Xiao Yan Li Yongshen Du Youwei | 2003 | Mater Sci & Engin B2003，99，： | 1 |
| 8 | Flower-like ZnO modified with BiOI nanoparticles as adsorption/catalytic bifunctional hosts for lithium–sulfur batteries显示文摘Due to the high specific capacity and energy density, lithium–sulfur battery is regarded as a potential energy storage conversion system. However, the serious shuttle effect and the sluggish electrochemical reaction kinetics impede the practical use of lithium–sulfur battery. In the interests of breaking through the above knotty problems, herein we propose to use the polar flower-like Zn O modified by Bi OI nanoparticles as bifunctional host with catalytic and adsorption ability for polysulfides in lithium–sulfur battery.It can be found that this adsorption/catalytic host integrates the functions of adsorption and mutual catalytic conversion of polysulfides, in which the polar flower-like Zn O can effectively capture the polysulfides through strong polar-polar interaction, simultaneously the BiOI nanoparticles can accelerate the mutual conversion of polysulfides to Li2 S through reducing the activation energy and conversion energy barrier required for the electrochemical reaction. As a result, under a sulfur loading of 2.5 mg cm^(-2), the lithium–sulfur battery with Zn O/Bi OI/CNT/S as cathode reveals a considerable initial specific capacity of1267 mAh g^(-1) at a current density of 0.1 C. Even the current density increased to 1 C, the capacity can reach as 873.4 mAh g^(-1), together with a good capacity retention of 67.1% after 400 cycles. Therefore,after systematically study the positive effects of the flower-like ZnO modified by catalytic BiOI nanoparticles on the adsorption and catalytic conversion of polysulfides, this work provides a new idea for the development and application of high-performance lithium–sulfur batteries. | Peng Zeng Hao Yu Manfang Chen Wensheng Xiao Yongfang Li Hong Liu Jing Luo Jiao Peng Dingsheng Shao Ziyi Zhou Zhigao Luo Ying Wang Baobao Chang Xianyou Wang | 2020 | Journal of Energy Chemistry2020，29，12： | 1 |
| 9 | Potential Effects of Episodic Deposition on Nutrients and Heavy Metals in Decomposing Litters of Suaeda glauca in Salt Marsh of the Yellow River Estuary, China显示文摘Episodic deposition has been recognized as a major factor affecting the decomposition rate of detrital material in salt marshes. In this paper, three one-off burial treatments, no burial treatment(0 cm, NBT), current burial treatment(10 cm, CBT) and strong burial treatment(20 cm, SBT), were designed in intertidal zone of the Yellow River Estuary to determine the potential influences of episodic deposition on nutrient(C, N) and heavy metal(Pb, Cr, Cu, Zn, Ni, Mn, Cd, V and Co) variations in decomposing litters of Suaeda glauca. Results showed that although various burial treatments showed no statistical difference in decomposition rate of S. glauca, the values generally followed the sequence of CBT(0.002 403/d) > SBT(0.002 195/d) > NBT(0.002 060/d). The nutrients and heavy metals in decomposing litters of the three burial treatments exhibited different variations except for N, Cu, Cr, Ni and Co. Except for Mn, no significant differences in C, N, Pb, Cr, Cu, Zn, Ni, V and Co concentrations occurred among the three treatments(P > 0.05). With increasing burial depth, Cr and Cd levels generally increased while Cu, Ni and Mn concentrations decreased. Although episodic deposition was generally favorable for C and N release from S. glauca, its influence on release was insignificant. In the three burial treatments, Pb, Cr, Zn, Ni, Mn, V and Co stocks in S. glauca generally evidenced the export of metals from litter to environment, and, with increasing burial depth, the export amounts increased greatly. The S. glauca were particular efficient in binding Cd and releasing Pb, Cr, Zn, Ni, Mn, V and Co, and, with increasing burial depth, stocks of Cu in decomposing litters generally shifted from release to accumulation. The experiment indicated that the potential eco-toxic risk of Pb, Cr, Zn, Ni, Mn, V and Co exposure would be serious as the strong burial episodes occurred in S. glauca marsh. | CHEN Bingbing SUN Zhigao | 2020 | Chinese Geographical Science2020，30，3： | 1 |
| 10 | A duck enteritis virus-veetored bivalent live vaccine provides fast and complete protection against H5N1 avian influenza virus infection in ducks显示文摘 | Liu Jinxiong Chen Pueheng Bu Zhigao | 2011 | J Virol2011，85，10： | 1 |
| 11 | Disorder and surface effects on work function of Ni-Pt metal gates显示文摘 | Xu Guigui Wu Qingyun Chen Zhigao | 2008 | Phys Rev B2008，78，11： | 1 |
| 12 | Effects of surface alloying and orientation on work function of MoTametal gate显示文摘 | Xu Guigui Wu Qingyun Chen Zhigao | 2009 | J Appl Phys2009，106，04： | 1 |
| 13 | Replication,pathogenicity,and transmission of SARS-CoV-2 in minks显示文摘Minks are raised in many countries and have transmitted severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)to humans.However,the biologic properties of SARS-CoV-2 in minks are largely unknown.Here,we investigated and found that SARS-CoV-2 replicates efficiently in both the upper and lower respiratory tracts,and transmits efficiently in minks via respiratory droplets;pulmonary lesions caused by SARS-CoV-2 in minks are similar to those seen in humans with COVID-19.We further found that a spike protein-based subunit vaccine largely prevented SARS-CoV-2 replication and lung damage caused by SARS-CoV-2 infection in minks.Our study indicates that minks are a useful animal model for evaluating the efficacy of drugs or vaccines against COVID-19 and that vaccination is a potential strategy to prevent minks from transmitting SARS-CoV-2. | Lei Shuai Gongxun Zhong Quan Yuan Zhiyuan Wen Chong Wang Xijun He Renqiang Liu Jinliang Wang Qinjian Zhao Yuxiu Liu Ningning Huo Junhua Deng Jingjing Bai Hongchao Wu Yuntao Guan Jianzhong Shi Kegong Tian Ningshao Xia Hualan Chen Zhigao Bu | 2021 | National Science Review2021，8，3： | 1 |
| 14 | Surface and size effects of magnetic properties in ferromagnetic nanoparticles 显示文摘 | Huang Zhigao Feng Qian Chen Zhigao | 2003 | Microelectronic Engineering2003，66，： | 1 |
| 15 | Comparison of the cumulative absolute velocity and acceleration peak value based on Wenchuan earthquake data显示文摘This paper discusses and presents the cumulative absolute velocity( CAV) parameters of the Wenchuan earthquake.Additionally,the CAV calculated from recorded data for the earthquake is compared to the peak ground acceleration( PGA),based on a brief analysis of background information.Accordingly,the paper studied the relationship between the CAV and PGA,and 3 CAV /PGA ratio charts were obtained in three different sub-directions.Linear and polynomial fitting operations were then used to analyze the potential discipline and characteristics in these directions.Finally,in the study,we investigated the applicability of using the CAV parameter for earthquake observation systems,and the CAV parameter was paired with the currently used PGA to provide earthquake observers and emergency responders with a theoretical basis. | Xia Jiening Chen Zhigao Huang Jun Yang Jiang Yang Jian Wu Peng | 2014 | Geodesy and Geodynamics2014，5，3： | 1 |
| 16 | Magnetization and configurational anisotropy in magnetic clusters:Monte Carlo simulation显示文摘 | Chen Zhigao Zhang Fengming | 2004 | Eur Phys J B2004，37，： | 1 |
| 17 | Front and Back contact engineering for high-efficient and low-cost hydrothermal derived Sb_(2)(S, Se)_(3) solar cells by using FTO/SnO_(2) and carbon显示文摘Antimony chalcogenide Sb_(2)(S, Se)_(3) is attracting a lot of attention as photovoltaic absorber owing to its rewarding photoelectric properties, low toxicity, and earth abundance. However, its device efficiency is still limited by the absorber material quality and device interface recombination. In this work, a fluorinedoped tin oxide(FTO) substrate with ultra-thin SnO_(2) layer and a low-cost stabilized carbon paste are introduced as a front and back contact layer respectively in Sb_(2)(S, Se)_(3) based planar solar cells. Over 5.2% efficiency is demonstrated in the structure of FTO/SnO_(2)/Cd S/Sb_(2)(S, Se)_3/Carbon/Ag, where the Sb_(2)(S, Se)_(3) is prepared by hydrothermal technique. The complementary device physics characterizations reveal that the interfacial recombination between TCO and Cd S is significantly suppressed by the introduction of ultra-thin SnO_(2) layer, which is profited from the leakage protection and bandgap offset engineering by its high resistivity and suitable conduction band minimum. Meanwhile, the successful adoption of the lowcost stabilized carbon as a back contact here shows an enormous potential to replace the conventional organic hole transport materials and noble metal. We hope this work can provide positive guidance to optimize Sb_(2)(S, Se)_(3) based planar solar cells in the future. | Liquan Yao Limei Lin Hui Liu Fengying Wu Jianmin Li Shuiyuan Chen Zhigao Huang Guilin Chen | 2020 | Journal of Materials Science & Technology2020，58，23： | 1 |
| 18 | Surfsce and size effect of magnetic properties in ferromagnetic nanoparticles显示文摘 | Feng Qian Chen Zhigao | 2003 | Microelectronic Engineering2003，66，： | 1 |
| 19 | Magnetism and work function of Ni-Cu alloys as metal gates显示文摘The magnetism and work function of pure Ni(001) and Ni-Cu slab alloys were investigated using first-principles methods based on density functional theory. The calculated results reveal that both magnetic moments and work functions of the alloys depend strongly on the surface orientation, but hardly on the distribution of doped Cu atoms for a given surface orientation. It is found that the doped Cu atoms have evident influence on the magnetic moment of Ni-Cu slabs, and the average magnetic moment of Ni atoms for Ni-Cu alloys decreases with increasing concentration of Cu atoms. Moreover, it is observed that the work function of Ni(001) is insensitive to the supercell thickness and the inner concentration of Cu atoms. In the meantime, the spin polarization is found to have an obvious role on the work function of the Ni-Cu alloys, which may give a new way to modulate the work function of the metal gate. | Cheng, Yanming Zheng, Yongping Huang, Xu Zhong, Kehua Chen, Zhigao Huang, Zhigao | 2012 | Rare Metals2012，31，2： | 1 |
| 20 | Magneic phase transition and size effect in thin magnetic film显示文摘 | Chen Zhigao Xiao Yan | 2003 | Materials Science and Engineering B2003，99，： | 1 |
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