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| 1 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008,,1: | 8 |
| 2 | High-density SNP-based genetic maps for the parents of an outcrossed and a selfed tetraploid garden rose cross, inferred from admixed progeny using the 68k rose SNP array显示文摘Dense genetic maps create a base for QTL analysis of important traits and future implementation of marker-assisted breeding.In tetraploid rose,the existing linkage maps include<300 markers to cover 28 linkage groups(4 homologous sets of 7 chromosomes).Here we used the 68k WagRhSNP Axiom single-nucleotide polymorphism(SNP)array for rose,in combination with SNP dosage calling at the tetraploid level,to genotype offspring from the garden rose cultivar‘Red New Dawn’.The offspring proved to be not from a single bi-parental cross.In rose breeding,crosses with unintended parents occur regularly.We developed a strategy to separate progeny into putative populations,even while one of the parents was unknown,using principle component analysis on pairwise genetic distances based on sets of selected SNP markers that were homozygous,and therefore uninformative for one parent.One of the inferred populations was consistent with self-fertilization of‘Red New Dawn’.Subsequently,linkage maps were generated for a bi-parental and a self-pollinated population with‘Red New Dawn’as the common maternal parent.The densest map,for the selfed parent,had 1929 SNP markers on 25 linkage groups,covering 1765.5 cM at an average marker distance of 0.9 cM.Synteny with the strawberry(Fragaria vesca)genome was extensive.Rose ICM1 corresponded to F.vesca pseudochromosome 7(Fv7),ICM4 to Fv4,ICM5 to Fv3,ICM6 to Fv2 and ICM7 to Fv5.Rose ICM2 corresponded to parts of F.vesca pseudochromosomes 1 and 6,whereas ICM3 is syntenic to the remainder of Fv6. | Mirjana Vukosavljev Paul Arens Roeland E Voorrips Wendy P C van't Westende G D Esselink Peter M Bourke Peter Cox W Eric van de Weg Richard G F Visser Chris Maliepaard Marinus J M Smulders | 2016 | Horticulture Research2016,3,1: | 6 |
| 3 | Bovine immunoglobulin protein isolates for the nutritional management of enteropathy显示文摘The gastrointestinal tract is responsible for a multitude of digestive and immune functions which depend upon the balanced interaction of the intestinal microbiota, diet, gut barrier function, and mucosal immune response. Disruptions in one or more of these factors can lead to intestinal disorders or enteropathies which are characterized by intestinal inflammation, increased gut permeability, and reduced capacity to absorb nutrients. Enteropathy is frequently associated with human immunodeficiency virus(HIV) infection, inflammatory bowel disease, autoimmune enteropathy, radiation enteritis, and irritable bowel syndrome(IBS), where pathologic changes in the intestinal tract lead to abdominal discomfort, bloating, abnormal bowel function(e.g., diarrhea, urgency, constipation and malabsorption). Unfortunately, effective therapies for the management ofenteropathy and restoring intestinal health are still not available. An accumulating body of preclinical studies has demonstrated that oral administration of plasmaor serum-derived protein concentrates containing high levels of immunoglobulins can improve weight, normalize gut barrier function, and reduce the severity of enteropathy in animal models. Recent studies in humans, using serum-derived bovine immunoglobulin/protein isolate, demonstrate that such protein preparations are safe and improve symptoms, nutritional status, and various biomarkers associated with enteropathy. Benefits have been shown in patients with HIV infection or diarrhea-predominant IBS. This review summarizes preclinical and clinical studies with plasma/serum protein concentrates and describes the effects on host nutrition, intestinal function, and markers of intestinal inflammation. It supports the concept that immunoglobulin-containing protein preparations may offer a new strategy for restoring functional homeostasis in the intestinal tract of patients with enteropathy. | Bryon W Petschow Anthony T Blikslager Eric M Weaver Joy M Campbell Javier Polo Audrey L Shaw Bruce P Burnett Gerald L Klein J Marc Rhoads | 2014 | World Journal of Gastroenterology2014,20,33: | 2 |
| 4 | Outcome of cytomegalovirus infections in patients with inflammatory bowel disease显示文摘 | Konstantinos A Papadakis Jim K Tung Scott W Binder Lori Y Kam Maria T Abreu Stephan R Targan Eric A Vasiliauskas | 2001 | The American Journal of Gastroenterology2001,,7: | 2 |
| 5 | A MyD88-dependent IFNyR-CCR2 signaling circuit is required for mobilization of monocytes and host defense against systemic bacterial challenge显示文摘 | Eric M Pietras Lloyd S Miller Carl T Johnson Ryan M O'Connell Paul W Dempsey Genhong Cheng | 2011 | Cell Research2011,21,7: | 2 |
| 6 | Inter-organizational knowledge transfer:Current themes and future prospects 显示文摘 | Mark E S Marjorie A L Eric W K T | 2008 | Journal of Management Studies2008,45,4: | 1 |
| 7 | A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome显示文摘 | Mark E Curran Igor Splawski Katherine W Timothy G.Michael Vincen Eric D Green Mark T Keating | 1995 | Cell1995,,: | 1 |
| 8 | Dual estimation and the unscented transformation显示文摘 | ERIC W RUDOLPH M NELSON A T | 2000 | Advances in neural information processing systems2000,12,1: | 1 |
| 9 | Thermodynamic properties for the alternative refrigerants显示文摘 | Mark O M Eric W L Richard T J | 1998 | Int J Refrig1998,21,4: | 1 |
| 10 | Antioxidant and antibacterial properties of green,black,and herbal teas of Camellia sinensis显示文摘 | Eric W C Eu Y S Pei P T | 2011 | Pharmacognosy Research2011,3,4: | 1 |
| 11 | Past and Projected Rural Land Conversion in the US at State, Regional, and National Levels显示文摘 | ERIC M W ANITA T M RALPH J A | 2009 | Landscape and Urban Planning2009,89,1: | 1 |
| 12 | Lowering the temperature of solid oxide fuel cells显示文摘 | ERIC D CHSMAN W LEE K T | 2011 | Science2011,334,: | 1 |
| 13 | A concept-relationship ac- quisition and inference approach for hierarchical taxonomy construc- tion from tags 显示文摘 | Eric T Wang W M Cheung C F | 2010 | Information Processing & Management2010,,1: | 1 |
| 14 | Acquiring knowledge by foreign partners from international joint ventures in a transition economy: Learning-by-doing and learning myopia 显示文摘 | Eric W K T | 2002 | Strategic Management Journal2002,23,9: | 1 |
| 15 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008,,1: | 1 |
| 16 | Bone marrow transdifferentiation in brain after transplantation: a retrospective study显示文摘 | Christopher R Cogle Anthony T Yachnis Eric D Laywell Dani S Zander John R Wingard Dennis A Steindler Edward W Scott | 2004 | The Lancet . 2004 (9419)2004,,9419: | 1 |
| 17 | Composite Shear Stud Strength at Early Concrete Ages显示文摘 | CEM T JOSEPH A Y ERIC B W | 2004 | Journal of Structural Engineering2004,130,6: | 1 |
| 18 | Effects of participation in a martial arts-based antibullying program in elementary schools 显示文摘 | Stuart W T Bridget K B Timothy D N Eric M V Peter F Stephen W T | 2008 | Psychology in the School2008,45,10: | 1 |
| 19 | Frequency dependence of antidepressant response to left prefrontal repetitive transcranial magnetic stimulation (rTMS) as a function of baseline cerebral glucose metabolism显示文摘 | Timothy A Kimbrell John T Little Robert T Dunn Mark A Frye Benjamin D Greenberg Eric M Wassermann Jennifer D Repella Aimee L Danielson Mark W Willis Brenda E Benson Andrew M Speer Elizabeth Osuch Mark S George Robert M Post | 1999 | Biological Psychiatry1999,,12: | 1 |
| 20 | An ontology-based similarity measure- ment for problem-based case reasoning 显示文摘 | Adela L Eric T Lee W B | 2009 | Expert Systems with Applications2009,36,: | 1 |