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| 1 | Episodic crustal anatexis and the formation of Paiku composite leucogranitic pluton in the Malashan Gneiss Dome, Southern Tibet显示文摘The Paiku composite leucogranitic pluton in the Malashan gneiss dome within the Tethyan Himalaya consists of tourmaline leucogranite,two-mica granite and garnet-bearing leucogranite.Zircon U-Pb dating yields that(1)tourmaline leucogranite formed at28.2±0.5 Ma and its source rock experienced simultaneous metamorphism and anatexis at 33.6±0.6 Ma;(2)two-mica granite formed at 19.8±0.5 Ma;(3)both types of leucogranite contain inherited zircon grains with an age peak at^480 Ma.These leucogranites show distinct geochemistry in major and trace elements as well as in Sr-Nd-Hf isotope compositions.As compared to the two-mica granites,the tourmaline ones have higher initial Sr and zircon Hf isotope compositions,indicating that they were derived from different source rocks combined with different melting reactions.Combined with available literature data,it is suggested that anatexis at^35 Ma along the Himalayan orogenic belt might have triggered the initial movement of the Southern Tibetan Detachment System(STDS),and led to the tectonic transition from compressive shortening to extension.Such a tectonic transition could be a dominant factor that initiates large scale decompressional melting of fertile high-grade metapelites along the Himalayan orogenic belt.Crustal anatexis at^28 Ma and^20 Ma represent large-scale melting reactions associated with the movement of the STDS. | GAO LiE ZENG LingSen HOU KeJun GUO ChunLi TANG SuoHan XIE KeJia HU GuYue WANG Li | 2013 | Chinese Science Bulletin2013，58，28： | 23 |
| 2 | Effect of Jiawei Shenfu decoction on tumor necrosis factor-alpha and nuclear factor-kappa B in patients who have chronic heart failure with syndromes of deficiency of heart Yang显示文摘OBJECTIVE:To examine the clinical efficacy of Jiawei Shenfu decoction on tumor necrosis factor-alpha (TNF-cα) and nuclear factor-kappa B (NF-KB) levels in patients who have chronic heart failure with syndromes of deficiency of heart Yang.METHODS:A total of 63 patients with syndromes of deficiency of heart Yang (chronic heart failure)were enrolled.Patients were randomly divided into the control group and Jiawei Shenfu group.All patients received standard medications for treatment of chronic heart failure.Patients in the Jiawei Shenfu group were additionally provided Jiawei Shenfu decoction one dose daily.Treatments continued for 4 consecutive weeks.The primary endpoint was the change in plasma B-type natriuretic peptide (BNP),NF-KB,and TNF-cα levels during 4 weeks of treatment.RESULTS:At the 4-week follow-up,a significant reduction in BNP levels compared with baseline was observed in both groups,but the Jiawei Shenfu decoction group showed a significantly greater reduction than did the control group.The Jiawei Shenfu group also showed superior performance regarding the Minnesota Living with Heart Failure Questionnaire score,the Chinese medicine syndrome score,heart rate,left ventricular ejection fraction,and 6-min walking distance compared with the control group.The degree of changes in NF-KB and TNF-α levels in the Jiawei Shenfu group was more significant than that in the control group.CONCLUSION:Routine medicine combined with Jiawei Shenfu decoction for patients with heart Yang deficiency syndrome in chronic heart failure can improve the left ventricular ejection fraction and cardiac function,and reduce BNP levels.The mechanism may be related to inhibition of pro-inflammatory cytokines and the NF-KB-induced kinase pathway,leading to amelioration of the inflammatory response. | Yu Mei Guo Hangyuan Ye Lingling Bian Jiaping Ma Lijuan Zheng Chunli | 2019 | Journal of Traditional Chinese Medicine2019，39，3： | 6 |
| 3 | Neoproterozoic magmatism in eastern Himalayan terrane显示文摘Geochronological investigation on gneisses of granitic to leucogranitic compositions in Cuona,south Tibet,reveal that their protoliths formed at 808.8 ± 7.9-816.4 ± 3.4 Ma and 855.8 ± 7.0 Ma,respectively.Zircon rims from the granitic gneiss record a metamorphic age of 739.4 ± 4.3 Ma.Lu-Hf isotopic analyses on zircon grains with Neoproterozoic ages yield negative ε_(Hf)(t) values from-9.0 to-4.2,and the corresponding two-stage Hf model ages are 1965-2228 Ma.Whole-rock geochemical data indicate that all granitic gneisses are K-riched calc-alkali series.These new data together with literature data show that(1) the Himalayan terrane experienced an episode of Neoproterozoic magmatism at 850-800 Ma;(2) the Neoproterozoic magma of granitic compositions were derived from partial melting of ancient crusts,possibly due to the thermal perturbation related with the breakup of the Rodinia supercontinent. | Yuhua Wang Lingsen Zeng Li-E Gao Chunli Guo Kejun Hou Lifei Zhang Wei Wang Huiyi Sun | 2017 | Science Bulletin2017，62，6： | 5 |
| 4 | Rapid Assessment on Potential Risks of Schistosomiasis Transmission—7 PLADs,China,2019 and 2021显示文摘Summary What is already known about this topic?Oncomelania hupensis(O.hupensis)and livestock are main infection sources of schistosomiasis.The schistosome infected O.hupensis and livestock’s feces are important risk factors in the transmission of schistosomiasis.What is added by this report?The potential risks of schistosomiasis transmission remain prevalent,giving an early warning to local government with information on existing transmission risks.It is expected that the effectiveness and efficiency of schistosomiasis surveillance could be improved by conducting rapid risk assessment at the beginning of transmission season. | Junyi He Hongqing Zhu Ziping Bao Lijuan Zhang Yinlong Li Ting Feng Suying Guo Wangping Deng Can Wang Hui Dang Tiewu Jia Chao Lyu Zhiqiang Qin Chunli Cao Jing Xu Shizhu Li Xiaonong Zhou | 2021 | China CDC weekly2021，3，51： | 5 |
| 5 | Activin A prevents neuron-like PC12 cell apoptosis after oxygen-glucose deprivation显示文摘In this study, PC12 cells were induced to differentiate into neuron-like cells using nerve growth facto and were subjected to oxygen-glucose deprivation. Cells were treated with 0, 10, 20, 30, 50, 100 ng/mL exogenous Activin A. The 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl tetrazolium bromide assay and Hoechst 33324 staining showed that the survival percentage of PC12 cells significantly decreased and the rate of apoptosis significantly increased after oxygen-glucose deprivation. Exogenous Activin A significantly increased the survival percentage of PC12 cells in a dose-dependent manner. Reverse transcription-PCR results revealed a significant increase in Activin receptor IIA, Smad3 and Smad4 mRNA levels, which are key sites in the Activin A/Smads signaling pathway, in neuron-like cells subjected to oxygen-glucose deprivation, while mRNA expression of the apoptosis-regulation gene caspase-3 decreased. Our experimental findings indicate that exogenous Activin A plays an anti-apoptotic role and protects neurons by means of activating the Activin A/Smads signaling pathway. | Guihua Xu Jinting He Hongliang Guo Chunli Mei Jiaoqi Wang Zhongshu Li Han Chen Jing Mang Hong Yang Zhongxin Xu | 2013 | Neural Regeneration Research2013，8，11： | 5 |
| 6 | In situ U-Pb dating of xenotime by laser ablation (LA)-ICP-MS显示文摘Xenotime is an ideal mineral for U-Th-Pb isotopic dating because of its relatively high U and Th contents, but typically low concentration of common Pb. These characteristics, and the fact that it is widespread throughout various types of rocks, suggest that the U-Th-Pb dating of xenotime has broad applications. Studies of U-Pb dating on xenotime by ion microprobe (such as SHRIMP) have increased in recent years, whereas studies by laser ablation (LA)-ICP-MS are still rare. In this study, we developed a technique for U-Pb dating of xenotime using the 193 nm ArF laser-ablation system and Agilent 7500a Q-ICP-MS. To evaluate the reliability of our method, a xenotime standard, BS-1, was analyzed and calibrated against another xenotime standard, MG-1. The weighted mean 206 Pb/ 238 U ages of 510.1 ± 5.2 Ma (2 n = 21), 509.8 ± 4.3 Ma (2 n = 21) and 510.0 ± 4.6 Ma (2 n = 21) were obtained using beam diameters of 16, 24 and 32 m, respectively. These ages are identical to those determined by ID-TIMS method (weighted mean 206 Pb/ 238 U age of 508.8 ± 1.4 Ma), which supports the reliability of our LA-ICP-MS method. We also analyzed xenotimes in leucogranites from South Tibet and granites from Xihuashan in southern China, and obtained accurate and precise ages. Nevertheless, we observed systematic differences in Pb/U fractionation among xenotime, monazite and zircon. The matrix-effect resulted in either under-correction or over-correction of fractionation, and thus led to inaccurate ages. Thus, a matrix-matched material is required for U-Pb dating of xenotime by LA-ICP-MS. | LIU ZhiChao WU FuYuan GUO ChunLi ZHAO ZiFu YANG JinHui SUN JinFeng | 2011 | Chinese Science Bulletin2011，56，27： | 5 |
| 7 | Nuclear Aurora kinase A switches m^(6)A reader YTHDC1 to enhance an oncogenic RNA splicing of tumor suppressor RBM4显示文摘Aberrant RNA splicing produces alternative isoforms of genes to facilitate tumor progression,yet how this process is regulated by oncogenic signal remains largely unknown.Here,we unveil that non-canonical activation of nuclear AURKA promotes an oncogenic RNA splicing of tumor suppressor RBM4 directed by m^(6)A reader YTHDC1 in lung cancer.Nuclear translocation of AURKA is a prerequisite for RNA aberrant splicing,specifically triggering RBM4 splicing from the full isoform(RBM4-FL)to the short isoform(RBM4-S)in a kinase-independent manner. | SiSi Li YangFan Qi JiaChuan Yu YuChao Hao Bin He MengJuan Zhang ZhenWei Dai TongHui Jiang SuYi Li Fang Huang Ning Chen Jing Wang MengYing Yang DaPeng Liang Fan An JinYao Zhao WenJun Fan YuJia Pan ZiQian Deng YuanYuan Luo Tao Guo Fei Peng ZhiJie Hou ChunLi Wang FeiMeng Zheng LingZhi Xu Jie Xu QingPing Wen BiLian Jin Yang Wang Quentin Liu | 2022 | Signal Transduction and Targeted Therapy2022，7，5： | 4 |
| 8 | Uranium sorption on oxyhydroxide minerals by surface complexation and precipitation显示文摘During the chemical weathering of the uranium mill tailings,released uranium could be immobilized by the newly formed secondary minerals such as oxyhydroxides.A deeper understanding of the interaction between uranium and common oxyhydroxides under environmental conditions is necessary.In this work,uranium sorption behaviors on Al-,Mn-and Fe-oxyhydroxide minerals(boehmite,manganite,goethite,and lepidocrocite)were investigated by batch experiments.Results showed that the uranium sorption on Al-oxyhydroxide behaved significantly differently from the other three minerals.The sorption edge of the Mn-and Fe-oxyhydroxides located around pH 5,while the sorption edge of boehmite shifted about 1.5 pH unit to near neutral.The sorption isotherms of uranium on manganite,goethite and lepidocrocite at pH 5.0 could be well fitted by the Langmuir model.Instead of surface complexation,sorption on boehmite happened mainly by uranium-bearing carbonates and hydroxides precipitation as illustrated by the characterization results.Both carbonate and phosphate strongly affected the uranium sorption behavior.The removal efficiency of uranium by boehmite exceeded 98%after three sorption-desorption cycles,indicating it may be a potential material for uranium removal and recovery. | Jingyi Wang Wanqiang Zhou Yanlin Shi Yao Li Dongfan Xian Ning Guo Chunli Liu | 2022 | Chinese Chemical Letters2022，33，7： | 3 |
| 9 | AtPEPTIDE RECEPTOR_2 mediates the AtPEPTIDE1‐induced cytosolic Ca^(2+) trise, which is required for the suppression of Glutamine Dumper gene expression in Arabidopsis roots显示文摘AtPEPTIDE RECEPTOR2(AtPEPR2) is a member of leucine‐rich repeat receptor‐like kinase family and binds to a group of AtPROPEP gene‐encoded endogenous peptides,AtPeps. Previously, we found that AtPEPR2 plays a moderate role in the AtPep1‐mediated innate immunity responses in Arabidopsis leaf. In this study, we found that AtPEPR2promoter has strong activity in the vascular tissues of the roots and the atpepr2 mutants showed a moderate but significantly shorter root phenotype. AtPEPR2 partially mediated AtPep1‐induced root elongation inhibition. AtPep1‐triggered cytosolic Ca2ttransient rise in roots showed partial dependence on AtPEPR2 and fully on extracellular Ca2t([Ca2t]ext). Transcriptional profiling analysis found that expression of 75% of AtPep1‐modulated genes in roots was fully dependent on AtPEPR2, of which two dramatically induced genes showed partial dependence on the [Ca2t]ext.Arabidopsis genome contains seven Glutamine Dumpers genes(AtGDUs), encoding amino acid exporters. Three of them(AtGDU2, 3, 5) were among the top 10 genes that were downregulated by AtPep1 through AtPEPR2 fully dependent pathway. Treatment with AtPep1 strongly suppressed promoter activity of AtGDU3 in roots, which was relieved by chelating [Ca2t]ext. Arabidopsis overexpressing AtGDU3showed a shorter root phenotype and decreased sensitivity to the AtPep1‐mediated inhibition of root elongation. Taken together, this study demonstrated a significant role of AtPEPR2 in the AtPep1‐mediated signaling in the roots. | Chunli Ma Jie Guo Yan Kang Kohei Doman Anthony C.Bryan Frans E.Tax Yube Yamaguchi Zhi Qi | 2014 | Journal of Integrative Plant Biology2014，56，7： | 3 |
| 10 | Mechanism for the Nanometer Scale Modification on HOPG Surface by Scanning Tunneling Microscope显示文摘A technique applying voltage across the tunnel junction for wnting permanent features on graphite with lines about 10nm wiidth using our home-built scanning tunneling microscope has been presented.Multiple-tip effects while modifying the surface are often met.The phenomciifi are explained in terms of the strong electric field existing at the junction between the tip an<7 the surface.In addition,the shape of the structure indented by the tip is in agreement with that of the tip. | WANG Zhonghuai DAI Changchun ZHANG Pingchen HUANG Guizhen LI Renli GUO Yi BAI Chunli | 1993 | Chinese Physics Letters1993，10，9： | 2 |
| 11 | Influence of Surface Nanocrystallization on Ti Ion Implantation of Pure Iron显示文摘In order to increase the depth or concentration of Ti ion implantation of pure iron, the surface mechanical attrition treatment(SMAT), which can fabricate a nanometer-grained surface layer without porosity and contamination in a pure iron plate, was used before ion implantation. Ti ion was implanted into the SMA treated sample and coarse-grained counterpart by using a metal vapor vacuum arc source implanter. The changing of depth and concentration of Ti was studied in a function of implantation time.By optical microscopy, transmission electron microscopy and X-ray diffraction, the grain size of the nano structured surface was studied. Micro-hardness, friction and wear behavior of nano surface layers were studied. By energy dispersive X-ray spectroscopy and Auger electron spectroscopy, the chemical composition and concentration of Ti ion in the surface implantation layer were studied. Experimental results showed that the concentration of Ti increased dramatically compared with untreated coarsegrained samples, which is attributed to the existence of higher density of defects(supersaturated vacancies, dislocations, non-equilibrium grain boundaries etc.) and compression stress field in the SMA treated nanocrystallined surface layer. The interaction between the defects and the implanted solute atoms leads to the increment of solid solubility. But the implantation depth showed inconspicuous change. It is shown that the ion range is just relevant to the energy and mass of the ion, dose of injection,the mass and density of target material. | Xu Li Yanli An Yinghui Wei Huayun Du Lifeng Hou Chunli Guo Hongbo Qu Yide Wang | 2015 | Journal of Materials Science & Technology2015，31，3： | 2 |
| 12 | Social insights on the implementation of One Health in zoonosis prevention and control: a scoping review显示文摘Background:The One Health (OH) concept has been promoted widely around the globe. OH framework is expected to be applied as an integrated approach to support addressing zoonotic diseases as a significant global health issue and to improve the efficiency and effectiveness of zoonosis prevention and control. This review is intended to overview the social impact of the implementation of OH on zoonosis prevention and control.Methods:A scoping review of studies in the past 10 years was performed to overview the integration feature of OH in zoonosis prevention and control and the social impacts of OH. PubMed and Web of Science were searched for studies published in English between January 2011 and June 2021. The included studies were selected based on predefined criteria.Results:Thirty-two studies were included in this review, and most of them adopted qualitative and semi-qualitative methods. More than 50% of the studies focused on zoonosis prevention and control. Most studies were conducted in low- and middle-income countries in Africa and Asia. Applying OH approach in diseases control integrates policymakers, stakeholders, and academics from various backgrounds. The impact of OH on economic is estimated that it may alleviate the burden of diseases and poverty in the long term, even though more financial support might be needed at the initial stage of OH implementation. OH implementation considers social and ecological factors related to zoonosis transmission and provides comprehensive strategies to assess and address related risks in different communities according to regions and customs.Conclusions:Based on reviewed literature, although there seems to be a lack of guidelines for assessing and visualizing the outcomes of OH implementation, which may limit the large-scale adoption of it, evidence on the contributions of implementing OH concepts on zoonosis prevention and control indicates long-term benefits to society, including a better integration of politics, stakeholders and academics to improve their cooperation, a potential to address economic issues caused by zoonosis, and a comprehensive consideration on social determinants of health during zoonosis prevention and control. | Junyi He Zhaoyu Guo Pin Yang Chunli Cao Jing Xu Xiaonong Zhou Shizhu Li | 2022 | Infectious Diseases of Poverty2022，11，3： | 1 |
| 13 | Correlation analysis of economic traits in Liaoning new breed of cashmere goats using microsatellite DNA Markers 显示文摘 | Jie Mei Guo Chunli HU Jinghui | 2006 | Acta Geneca Sinica2006，33，3： | 1 |
| 14 | A new centimeterdiameter Cu-based bulk metallic glass显示文摘 | Dai Chunli Guo Hua Shen Yong | 2006 | Scr Mater2006，54，： | 1 |
| 15 | Porphyry Cu–Au–Mo–epithermal Ag–Pb–Zn–distal hydrothermal Au deposits in the Dexing area, Jiangxi province, East China—A linked ore system显示文摘 | Jingwen Mao Jiandong Zhang Franco Pirajno Daizo Ishiyama Huimin Su Chunli Guo Yuchuan Chen | 2011 | Ore Geology Reviews2011，，1： | 1 |
| 16 | The Nursee-Nurse Collaboration Behavior Scale:Development and psychometric testing显示文摘Objective:To develop and test the reliability and validity of a new instrument,the Nurse eNurse Collaboration Behavior Scale(NNCBS).Background:The importance of cooperation among nurses is widely acknowledged,but is a lack of scientific studies regarding the behaviorial interactions associated with nurse enurse relationships throughout the process of patient-centered care.Therefore,there is a great need to develop a reliable scale to measure nurseenurse collaboration behavior,which is what we have generated in this study.Methods:The 46-item Nursee-Nurse Collaboration Scale was developed using a process of item design,refinement,and testing for both reliability and validity.In 2014,the 202 nurses from the International Department of Services participated in this pilot study.Cronbach's a coefficients and testeretest reliability coefficients were calculated in order to evaluate this new scale's internal consistency and stability.Exploratory factor analysis was calculated using a principal factor method with promax rotation to evaluate the scale's validity.Results:Exploratory factor analysis yielded four factors and 23 items.The overall Cronbach's a coefficient of the scale was 0.929.The item-total correlation values were overall high,ranging from 0.427 to 0.751.For the entire scale,the r values of the testeretest reliability correlations were 0.764.Conclusion:The NNCB Scale developed in this study demonstrates acceptable reliability and validity for measuring the level of NNCB.Its implementration on a broader scale would at the very least guide and promote collaborative relationships between nurses involved in patient care.It should be noted that the scale requires further psychometric testing using a larger sample size of nurses who also represent a wider diversity of backgrounds,as well as researchers who are encouraged to improve the instrument. | Chunli Liao Ying Qin Yue He Yu Guo | 2015 | International Journal of Nursing Sciences2015，2，4： | 1 |
| 17 | A review of the geological characteristics and geodynamic setting of Late Paleozoic porphyry copper deposits in the Junggar region, Xinjiang Uygur Autonomous Region, Northwest China显示文摘 | Fuquan Yang Jingwen Mao Franco Pirajno Shenghao Yan Guoren Liu Gang Zhou Zhixin Zhang Feng Liu Xinxia Geng Chunli Guo | 2011 | Journal of Asian Earth Sciences2011，，： | 1 |
| 18 | Strontium isotope characterization and major ion geochemistry of karst water flow, Shentou, northern China 显示文摘 | Wang Yanxin Guo Qinghai Su Chunli Ma Teng | 2006 | J Hydrol2006，328，34： | 1 |
| 19 | GISH AFLP and PCR-RFLP analysis of an intergeneric somatic hybrid combining Goutou sour orange and Poncirus trifoliate显示文摘 | Fu Chunhua Chen Chunli Guo Wenwu | 2004 | Plant Cell Rep2004，23，6： | 1 |
| 20 | Near optimal compressedsensing priors : Parametric sure approximate messagepassing显示文摘 | GUO Chunli DAVIES M E | 2015 | Signal Processing2015，63，8： | 1 |
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