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| 1 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 2 | Immunological synergistic mechanisms of trans-/cis-stilbene glycosides in Heshouwu-related idiosyncratic liver injury显示文摘Heshouwu is a traditional non-toxic Chinese medicine commonly used in the clinical setting;however,clinical cases of Heshouwu-induced hepatotoxicity have been frequently reported^([1]).Pharmacoepidemiological studies have found that Heshouwu-induced liver injury occurs only in a small fraction of individuals taking the drug;these patients presented with the typ- | Lanzhi He Ping Yin Yakun Meng Jinfa Tang Tingting He Ming Niu Yuming Guo Yun Zhu Jing Jing Chunyu Li Zhijie Ma Jiabo Wang Zhaofang Bai Xiaohe Xiao | 2017 | Science Bulletin2017，62，11： | 29 |
| 3 | Guidance for the clinical evaluation of traditional Chinese medicine-induced liver injury Issued by China Food and Drug Administration显示文摘1. Introduction Drug-induced liver injury (DILI), defined as liver injury caused by a drug and/or its metabolites, is a common clinical adverse drug reaction1–4. This type of injury can cause acute liver failure and even death in severe cases5. | Xiaohe Xiao Jianyuan Tang Yimin Mao Xiuhui Li Jiabo Wang Chenghai Liu Kewei Sun Yong’an Ye Zhengsheng Zou Cheng Peng Ling Yang Yuming Guo Zhaofang Bai Tingting He Jing Jing Fengyi Li Na An | 2019 | Acta Pharmaceutica Sinica B2019，9，3： | 22 |
| 4 | Landscape of DILI-related adverse drug reaction in China Mainland显示文摘Drug-induced liver injury(DILI)is a type of bizarre adverse drug reaction(ADR)damaging liver(L-ADR)which may lead to substantial hospitalizations and mortality.Due to the general low incidence,detection of L-ADR remains an unsolved public health challenge.Therefore,we used the data of 6.673 million of ADR reports from January 1st,2012 to December 31st,2016 in China National ADR Monitoring System to establish a new database of L-ADR reports for future investigation.Results showed that totally 114,357 ADR reports were retrieved by keywords searching of liver-related injuries from the original heterogeneous system.By cleaning and standardizing the data fields by the dictionary of synonyms and English translation,we resulted 94,593 ADR records reported to liver injury and then created a new database ready for computer mining.The reporting status of L-ADR showed a persistent 1.62-fold change over the past five years.The national population-adjusted reporting numbers of L-ADR manifested an upward trend with age increasing and more evident in men.The annual reporting rate of L-ADR in age group over 80 years old strikingly exceeded the annual DILI incidence rate in general population,despite known underreporting situation in spontaneous ADR reporting system.The percentage of herbal and traditional medicines(H/TM)L-ADR reports in the whole number was 4.5%,while 80.60%of the H/TM reports were new findings.There was great geographical disparity of reported agents,i.e.more cardiovascular and antineoplastic agents were reported in higher socio-demographic index(SDI)regions and more antimicrobials,especially antitubercular agents,were reported in lower SDI regions.In conclusion,this study presented a large-scale,unbiased,unified,and computer-minable L-ADR database for further investigation.Age-,sex-and SDI-related risks of L-ADR incidence warrant to emphasize the precise pharmacovigilance policies within China or other regions in the world. | Jiabo Wang Haibo Song Feilin Ge Peng Xiong Jing Jing Tingting He Yuming Guo Zhuo Shi Chao Zhou Zixin Han Yanzhong Han Ming Niu Zhaofang Bai Guangbin Luo Chuanyong Shen Xiaohe Xiao | 2022 | Acta Pharmaceutica Sinica B2022，12，12： | 12 |
| 5 | Spider web-like carbonized bacterial cellulose/MoSe_(2) nanocomposite with enhanced microwave attenuation performance and tunable absorption bands显示文摘It is essential to manufacture microwave absorbers with strong absorption as well as tunable absorption bands at a low filler content.However,it remains challenging for pure biomass material to reach this goal without loading other components.MoSe_(2),as a transition metal chalcogenide with semiconductor properties,has emerged as a potential microwave absorber filler.Herein,bacterial cellulose(BC)-derived carbon nanofibers/MoSe_(2) nanocomposite was fabricated and phosphoric acid was used to dope phosphorus in BC,in which MoSe_(2) microspheres were dropped on the BC network like a dew-covered spider web.This unique network structure enhances conductive loss and multiple reflections of the incident wave.The collocation of BC and MoSe_(2) is helpful to impedance match and introduces interfacial/dipolar polarization loss;moreover,the P-doping of BC helps to tune the absorption bands.Overall,the optimal reflection loss of undoped one reaches−53.33 dB with only 20 wt.%filler content,whose main absorption peaks focus on X-band.Interestingly,after the P-doping of BC,the main absorption peaks move to Ku-band and the optimal reflection loss gets stronger(−66.84 dB)with the same filler loading.Strong absorption and tunable absorption bands can be realized,and thus wide frequency range is covered.This work is expected to enlighten future exploration of biomass carbon materials on high-performance microwave absorption materials. | Zhengjian Xu Man He Yuming Zhou Shuangxi Nie Yongjuan Wang Yao Huo Yifan Kang Ruili Wang Ran Xu Hao Peng Xi Chen | 2021 | Nano Research2021，14，3： | 6 |
| 6 | Bevacizumab biosimilar LY01008 compared with bevacizumab(Avastin)as first-line treatment for Chinese patients with unresectable,metastatic,or recurrent non-squamous non-small-cell lung cancer:A multicenter,randomized,double-blinded,phase Ⅲ trial显示文摘Background:Previous studies have demonstrated the preclinical pharmacological and toxicological consistency,and clinical pharmacokinetic equivalence of bevacizumab biosimilar LY01008 with reference bevacizumab(Avastin).This randomized controlled trial aimed to compare the efficacy and safety of LY01008 with Avastin in first-line treatment of Chinese patients with advanced or recurrent non-squamous non-small cell lung cancer(NSCLC).Methods:StageⅢB-ⅣNSCLC patients with evaluable lesions,good physical status,and adequate organ functions from 67 centers across China were randomized in a ratio of 1:1 to receive LY01008 or Avastin 15 mg/kg intravenously in combination with paclitaxel/carboplatin(combined treatment)for 4-6 cycles,followed by maintenance monotherapy with LY01008 until disease progression,intolerable toxicity,or death.The primary endpoint was objective response rate(ORR)in accordance with Response Evaluation Criteria in Solid Tumors(RECIST)version 1.1 confirmed by independent radiological review committees(IRRC).Secondary endpoints included disease control rate(DCR),duration of response(DoR),progression-free survival(PFS),overall survival(OS),and safety.This study was registered in Clinical Trials.gov(NCT03533127).Results:Between December 15^(th),2017,and May 15^(th),2019,a total of 649 patients were randomized to the LY01008(n=324)or Avastin(n=325)group.As of September 25th,2019 for primary endpoint analysis,589 patients received ORR evaluation,with a median number of combined treatment cycles of 5(range 1-6)andmedian duration of treatment of 3.0(range 0.0-5.1)months.ORRof responseevaluable patients in the LY01008 and Avastin groups were 48.5% and 53.0%,respectively.The stratified ORR ratio was 0.91(90%CI 0.80-1.04,within the prespecified equivalence margin of 0.75-1.33).Up to May 15^(th),2020,with a median follow-up of 13.6(range 0.8-28.4)months,no notable differences in DCR,median DoR,median PFS,median OS,and 1-year OS rate were observed between the LY01008 and Avastin groups.There were no clinically meaningful differences in safety and immunogenicity across treatment groups.Conclusions:LY01008 demonstrated similarity to Avastin in terms of efficacy and safety in Chinese patients with advanced or recurrent non-squamous NSCLC.LY01008 combined with paclitaxel/carboplatin is expected to become a new treatment option for unresectable,metastatic,LY01008 and Avastin groups.There were no clinically meaningful differences in safety and immunogenicity across treatment groups.Conclusions:LY01008 demonstrated similarity to Avastin in terms of efficacy and safety in Chinese patients with advanced or recurrent non-squamous NSCLC.LY01008 combined with paclitaxel/carboplatin is expected to become a new treatment option for unresectable,metastatic,or recurrent non-squamous NSCLC patients in the first-line setting. | Yuankai Shi Kaijian Lei Yuming Jia Bingqiang Ni Zhiyong He Minghong Bi Xicheng Wang Jianhua Shi Ming Zhou Qian Sun Guolei Wang Dongji Chen Yongqian Shu Lianke Liu Zhongliang Guo Yong Liu Junquan Yang Ke Wang Ke Xiao LinWu Tienan Yi Debin Sun Mafei Kang Tianjiang Ma Yimin Mao Jinsheng Shi Tiegang Tang Yan Wang Puyuan Xing Dongqing Lv Wangjun Liao Zhiguo Luo Bin Wang Xiaohong Wu Xiaoli Zhu Shuhua Han Qisen Guo Rongyu Liu Zhiwei Lu Jianyong Zhang Jian Fang Changlu Hu Yinghua Ji Guolong Liu Hong Lu Dedong Wu Junhong Zhang Shuyang Zhu Zheng Liu Wensheng Qiu Feng Ye Yan Yu Yanqiu Zhao Qinhong Zheng Jun Chen Zhanyu Pan Yiping Zhang Wenjuan Lian Bo Jiang Bo Qiu Guojun Zhang Hua Zhang Yanju Chen Yuan Chen Hongbing Duan Manxiang Li Shengming Liu Lijun Ma Hongming Pan Xia Yuan Xueli Yuan Yulong Zheng Emei Gao Li Zhao Shumin Wang Can Wu | 2021 | Cancer Communications2021，41，9： | 5 |
| 7 | Research progress in electrospinning engineering for all-solid-state electrolytes of lithium metal batteries显示文摘Owing to safety issue and low energy density of liquid lithium-ion batteries(LIBs),all-solid-state lithium metal batteries(ASLMBs)with unique all-solid-state electrolytes(SEs)have attracted wide attentions.This arises mainly from the advantages of the SEs in the suppression of lithium dendrite growth,long cycle life,and broad working temperature range,showing huge potential applications in electronic devices,electric vehicles,smart grids,and biomedical devices.However,SEs suffer from low lithiumion conductivity and low mechanical integrity,slowing down the development of practical ASLMBs.Nanostructure engineering is of great efficiency in tuning the structure and composition of the SEs with improved lithium-ion conductivity and mechanical integrity.Among various available technologies for nanostructure engineering,electrospinning is a promising technique because of its simple operation,cost-effectiveness,and efficient integration with different components.In this review,we will first give a simple description of the electrospinning process.Then,the use of electrospinning technique in the synthesis of various SEs is summarized,for example,organic nanofibrous matrix,organic/inorganic nanofibrous matrix,and inorganic nanofibrous matrix combined with other components.The current development of the advanced architectures of SEs through electrospinning technology is also presented to provide references and ideas for designing high-performance ASLMBs.Finally,an outlook and further challenges in the preparation of advanced SEs for ASLMBs through electrospinning engineering are given. | Manxi Wang Yaling Wu Min Qiu Xuan Li Chuanping Li Ruiling Li Jiabo He Ganggang Lin Qingrong Qian Zhenhai Wen Xiaoyan Li Ziqiang Wang Qi Chen Qinghua Chen Jinhyuk Lee Yiu-Wing Mai Yuming Chen | 2021 | Journal of Energy Chemistry2021，30，10： | 4 |
| 8 | Comparative study on pattern recognition receptors in non-teleost ray-finned fishes and their evolutionary significance in primitive vertebrates显示文摘Pattern recognition receptors(PRRs) play important roles in innate immunity system and trigger the specific pathogen recognition by detecting the pathogen-associated molecular patterns. The main four PRRs components including Toll-like receptors(TLRs), RIG-I-like receptors(RLRs), NOD-like receptors(NLRs) and C-type lectin receptors(CLRs) were surveyed in the five genomes of non-teleost ray-finned fishes(NTR) including bichir(Polypterus senegalus), American paddlefish(Polyodon spathula), alligator gar(Atractosteus spatula), spotted gar(Lepisosteus oculatus) and bowfin(Amia calva), representing all the four major basal groups of ray-finned fishes. The result indicates that all the four PRRs components have been well established in these NTR fishes. In the RLR-MAVS signal pathway, which detects intracellular RNA ligands to induce production of type I interferons(IFNs), the MAVS was lost in bichir particularly. Also, the essential genes of recognition of Lipopolysaccharide(LPS) commonly in mammals like MD2, LY96 and LBP could not be identified in NTR fishes. It is speculated that TLR4 in NTR fishes may act as a cooperator with other PRRs and has a different pathway of recognizing LPS compared with that in mammals. In addition, we provide a survey of NLR and CLR in NTR fishes. The CLRs results suggest that Group V receptors are absent in fishes and Group II and VI receptors are well established in the early vertebrate evolution. Our comprehensive research of PRRs involving NTR fishes provides a new insight into PRR evolution in primitive vertebrate. | Yuming He Hailin Pan Guojie Zhang Shunping He | 2019 | Science China(Life Sciences)2019，62，4： | 4 |
| 9 | Second Generation Wavelet Finite Element and Rotor Cracks Quantitative Identification Method显示文摘The presence of cracks in the rotor is one of the most dangerous and critical defects for rotating machinery.Defect of fatigue cracks may lead to long out-of-service periods,heavy damages of machines and severe economic consequences.With the method of finite element,vibration behavior of cracked rotors and crack detection was received considerable attention in the academic and engineering field.Various researchers studied the response of a cracked rotor and most of them are focused on the crack detection based on vibration behavior of cracked rotors.But it is often difficult to identify the crack parameters quantitatively.Second generation wavelets (SGW) finite element has good ability in modal analysis for singularity problems like a cracked rotor.Based on the fact that the feature of SGW could be designed depending on applications,a multiresolution finite element method is presented.The new model of SGW beam element is constructed.The first three natural frequencies of the rotor with different crack location and size were solved with SGW beam elements,and the database for crack diagnosis is obtained.The first three metrical natural frequencies are employed as inputs of the database and the intersection of the three frequencies contour lines predicted the normalized crack location and size.With the Bently RK4 rotor test rig,rotors with different crack location and size are tested and diagnosed.The experimental results denote the cracks quantitative identification method has higher identification precision.With SGW finite element method,a novel method is presented that has higher precision and faster computing speed to identify the crack location and size. | CHEN Xuefeng LI Bing HE Yuming HE Zhengjia | 2010 | Chinese Journal of Mechanical Engineering2010，23，2： | 3 |
| 10 | Overview of the Solar Polar Orbit Telescope Project for Space Weather Mission显示文摘The Solar Polar ORbit Telescope(SPORT) project for space weather mission has been under intensive scientific and engineering background studies since it was incorporated into the Chinese Space Science Strategic Pioneer Project in 2011.SPORT is designed to carry a suite of remote-sensing and in-situ instruments to observe Coronal Mass Ejections(CMEs),energetic particles,solar high-latitude magnetism,and the fast solar wind from a polar orbit around the Sun.The first extended view of the polar regions of the Sun and the ecliptic enabled by SPORT will provide a unique opportunity to study CME propagation through the inner heliosphere,and the solar high-latitude magnetism giving rise to eruptions and the fast solar wind.Coordinated observations between SPORT and other spaceborne/ground-based facilities within the International Living With a Star(ILWS) framework can significantly enhance scientific output.SPORT is now competing for official selection and implementation during China's 13 th Five-Year Plan period of 2016-2020. | XIONG Ming LIU Ying LIU Hao LI Baoquan ZHENG Jianhua ZHANG Cheng XIA Lidong ZHANG Hongxin RAO Wei CHEN Changya SUN Weiying WU Xia DENG Yuanyong HE Han JIANG Bo WANG Yuming WANG Chuanbing SHEN Chenglong ZHANG Haiying ZHANG Shenyi YANG Xuan SANG Peng WU Ji | 2016 | 空间科学学报2016，36，3： | 3 |
| 11 | Surface modification of polyolefin separators for lithium ion batteries to reduce thermal shrinkage without thickness increase显示文摘Surface chemical modification of polyolefin separators for lithium ion batteries is attempted to reduce the thermal shrinkage, which is important for the battery energy density. In this study, we grafted organic/inorganic hybrid crosslinked networks on the separators, simply by grafting polymerization and condensation reaction. The considerable silicon-oxygen crosslinked heat-resistance networks are responsible for the reduced thermal shrinkage. The strong chemical bonds between networks and separators promise enough mechanical support even at high temperature. The shrinkage at 150 C for 30 min in the mechanical direction was 38.6% and 4.6% for the pristine and present graft-modified separators, respectively. Meanwhile, the grafting organic-inorganic hybrid crosslink networks mainly occupied part of void in the internal pores of the separators, so the thicknesses of the graft-modified separators were similar with the pristine one. The half cells prepared with the modified separators exhibited almost identical electrochemical properties to those with the commercial separators, thus proving that, in order to enhance the thermal stability of lithium ion battery, this kind of grafting-modified separators may be a better alternative to conventional silica nanoparticle layers-coated polyolefin separators. | Peng Zhao Juping Yang Yuming Shang Li Wang Mou Fang Jianlong Wang Xiangming He | 2015 | Journal of Energy Chemistry2015，24，2： | 3 |
| 12 | A Novel Method for Power Analysis Based on Combinational Logic in Block Cipher Circuit显示文摘In this paper, we propose a method that builds power model template according to input transitions of combinatorial logic circuit. By computing its correlation with the overall power consumption of a cryptographic circuit, we are able to recover the secret key. Several simulation-based experiments have been conducted,which verifies the feasibility of our method and shows that the combinatorial logic is also faced with the problem of information leakage in power analysis cases. Compared with DPA(Differential power analysis) and CPA(Correlation power analysis), our attack is fairly effective against the cryptographic circuits whose protection is only implemented on the register parts of the sequential circuit. In addition, a few topics for further research, as well as the advices for more precise power model and countermeasures,are presented at the end of the paper. | GUO Zheng GU Dawu YUAN Kan LIU Junrong HE Yuming | 2014 | Chinese Journal of Electronics2014，23，1： | 2 |
| 13 | DEFORMATION MEASUREMENT USING DUAL-FREQUENCY PROJECTION GRATING PHASE-SHIFT PROFILOMETRY显示文摘当一个使变形的目标有时, 2 蟺阶段歧义问题在阶段测量是很重要的一从飞机大排水量。双频率的设计栅栏阶段 -- 变的 profilometry (PSP ) 能被用来解决如此的一个问题。在测量,二合适 -- 选择频率栅栏被利用综合在一个主要阶段范围保证计算阶段的一个相等的波长栅栏。因此,错误与常规阶段由阶段 unwrapping 过程引起了重建算法能被消除。最后,有大塑料变丑的一个标本的试验性的结果被给证明建议方法是有效的处理阶段断绝。 | Yanming Chen Yuming He Eryi Hu Hongmao Zhu | 2008 | Acta Mechanica Solida Sinica2008，21，2： | 2 |
| 14 | Effect of Morphological Structure of PtSnNa/ZSM-5 on Its Catalytic Performance in Propane Dehydrogenation显示文摘The ZSM-5 zeolite with flower-shaped crystallites(marked as ZFS)was synthesized through the hydrothermal preparation method.The properties of ZFS as a supporting material have been investigated in comparison with the traditional ZSM-5 zeolite.The prepared samples were characterized by XRD,N2 adsorption-desorption,TEM,NH3-TPD,XRF,and XPS techniques.The results showed that the formation of the flower-shaped crystallites directly influenced the physicochemical properties of ZFS material.In ZFS,the pore structure was changed,the acid content was decreased,and the surface properties were promoted.Besides,in the PtSnNa/ZFS catalyst,the amount of oxidized Sn species was remarkably increased and the dispersion of Pt was relatively improved.Meanwhile,due to these modifications,the capacity of the catalyst supported on ZFS to accommodate coke was greatly improved and the coke deposits on PtSnNa/ZFS were migrated from active metals to the support.Furthermore,as expected,the catalytic performance of the PtSnNa/ZFS catalyst for propane dehydrogenation to propylene and the stability of catalyst were significantly improved. | Wang Yongjuan Zhou Yuming Zhou Shijian He Qiang Zhong Yangyang | 2020 | China Petroleum Processing & Petrochemical Technology2020，22，1： | 2 |
| 15 | Exogenous nerve growth factor supplementation elevates myocardial immunoreactivity and attenuates cardiac remodeling in pressure-overload rats显示文摘外长的神经生长因素(NGF ) 的补充可能调停,这被要求在心失败(HF ) 的心脏的同情的神经功能的改进。心脏的同情的 ganglia 附近的 NGF 的本地肌内的注射能影响神经分布模式,新肾上素 transporter (网) 基因表示,并且改进在试验性的 HF 动物的心脏的改变。在这研究,我们与腹的大动脉的收缩(交流) 把 NGF 注入了 SpragueDawley 老鼠的 scalenus medius 肌肉。神经与交流在老鼠刺激了模式,左室的形态学,和功能追随者注射被 immunohistochemistry 和 echocardiography 分别地调查。网络的 mRNA 表示的层次,生长联系了蛋白质 43 (差距 43 ) , NGF 和它的受体 TrkA 和 p75NTR,和大脑 natriuretic 肽(BNP ) 被即时聚合酶链反应测量。结果证明心肌的 NGF mRNA 层次在有交流的老鼠是可比较的。外长的 NGF 的短期的补充提起了心肌的 NGF immunoreactivity,但是没在交流老鼠引起 hyperinnervation 和网 mRNA upregulation。而且,心肌的 TrkA mRNA 被发现显著地被减少, p75NTR mRNA 被增加。心肌的 TrkA downregulation 可以为避免 hyperinnervation 玩有益的效果,并且要求是合理的那 p75NTR 能当 TrkA 不在时作为 NGF 受体工作。有趣地,进 ganglia 附近的颈肌肉的本地 NGF 管理能稀释心脏的改变和 downregulate BNP mRNA。这些结果建议外长的 NGF 能 anterogradely 沿着轴突到达目标织物,并且改进心脏的改变。 | Bing He Fan Ye Xin Zhou He Li Xiaoqing Xun Xiaoqing Ma Xudong Liu Zhihong Wang Pengxiao Xu Yuming Li | 2012 | Acta Biochimica et Biophysica Sinica2012，44，11： | 2 |
| 16 | Asari Radix et Rhizoma consumption lacks relevance for hepatocellular carcinoma in patients:A retrospective cohort study显示文摘Objective:Although some studies have linked Asari Radix et Rhizoma(Asari Radix)administration to hepatocellular carcinoma(HCC),few studies have examined the association between the development of HCC and use of Asari Radix among patients in China's Mainland.This study aimed to evaluate the realworld association between Asari Radix and HCC in patients to strengthen the understanding of Asari Radix safety.Methods:A retrospective cohort study among hepatitis B virus(HBV)-monoinfected patients and nonHBV-monoinfected patients were performed.Patients over 18 years of age were eligible for inclusion.Prescription records of inpatients and outpatients were inquired to distinguish Asari Radix users and nonusers.The risk of developing HCC among Asari Radix users and nonusers in the HBV cohort and the non-HBV cohort was analyzed.Results:There were 49500 HBV and 133148 non-HBV patients involved in the two cohorts.Among HBV patients(2901 users;46599 nonusers),the prevalence of HCC in Asari Radix users was lower than that in nonusers(145.70 vs.265.43 per 105).Among non-HBV patients(5042 users;128106 nonusers),the prevalence of HCC in Asari Radix users was lower than that in nonusers(81.62 vs.134.11 per 105).None of the hazard ratios(HRs)of Asari Radix exposure ranging from 1 g to 200 g in the two cohorts showed correlation between Asari Radix exposure and hepatocarcinogenesis.Conclusion:An obvious irrelevancy was found between the consumption of Asari Radix and HCC development both in patients with and in those without HBV infection.Use of Asari Radix under 200 g appears safe in terms of HCC risk in the Chinese population;further prospective studies are needed to confirm our results. | Zhi-e Fang Yuming Guo Zhilei Wang Tingting He Jiabo Wang Zhaofang Bai Xiaohe Xiao | 2022 | Chinese Herbal Medicines2022，14，3： | 2 |
| 17 | Electrospinning Engineering Enables High‑Performance Sodium‑Ion Batteries显示文摘As a promising energy storage device,sodium-ion batteries(SIBs)have received continuous attention due to their low-cost and environmental friendliness.However,the sluggish kinetics of Na ion usually makes SIBs hard to realize desirable electrochemical performance when compared to lithium-ion batteries(LIBs).The key to addressing this issue is to build up nanostructured materials which enable fast Na-ion insertion/extraction.One-dimensional(1D)nanocarbons have been considered as both the anode and the matrix to support active materials for SIB electrodes owing to their high electronic conductivity and excellent mechanical property.Because of their large surface areas and short ion/electron difusion path,the synthesized electrodes can show good rate performance and cyclic stability during the charge/discharge processes.Electrospinning is a simple synthetic technology,featuring inexpensiveness,easy operation and scalable production,and has been largely used to fabricate 1D nanostructured composites.In this review,we frst give a simple description of the electrospinning principle and its capability to construct desired nanostructures with diferent compositions.Then,we discuss recent developments of carbon-based hybrids with desired structural and compositional characteristics as the electrodes by electrospinning engineering for SIBs.Finally,we identify future research directions to realize more breakthroughs on electrospun electrodes for SIBs. | Chuanping Li Min Qiu Ruiling Li Xuan Li Manxi Wang Jiabo He Ganggang Lin Liren Xiao Qingrong Qian Qinghua Chen Junxiong Wu Xiaoyan Li Yiu‑Wing Mai Yuming Chen | 2022 | Advanced Fiber Materials2022，4，1： | 1 |
| 18 | Comparison of Lipid Levels, Hyperlipidemia Prevalence and Its Risk Factors between Guangxi Hei Yi Zhuang and Han Populations显示文摘 | Yin Ruixing Chen Yuming Pan Shangling He Fengping Liu Tangwei Yang Dezhai Wu Jinzhen Yao Limei Lin Weixiong Li Rongshan Huang Jiandong | 2006 | Archives of Medical Research2006，，6： | 1 |
| 19 | Effects of proton radiation on field limiting ring edge terminations in 4H–SiC junction barrier Schottky diodes显示文摘In this study, the effects of high-energy proton radiation on the effectiveness of edge terminations using field limiting rings(FLRs) in 4 H–SiC junction barrier Schottky(JBS) diodes were examined in detail. The devices were irradiated using 5-MeV protons at fluences ranging from 5×10^12 cm^-2 to 5×10^14 cm^-2. Further, the reverse breakdown performances of the investigated devices were measured both before and after irradiation. Proton irradiation initially decreased the breakdown voltage(BV);subsequently, the BV was increased as the proton fluence increased. At a fluence of 5×10^13 cm^-2, the BV was reduced by approximately 18%, whereas it was reduced by approximately 5% at a higher proton fluence of 5×10^14 cm^-2. The related degradation mechanism that was associated with this phenomenon was also investigated using the numerical simulations of the current-voltage(I-V) and capacitance-voltage(C-V) characteristics of the device. The main contribution to the radiation-induced changes in BV originates from the variations of charge distribution at the SiO2/4 H–SiC interface and the reduction of the net carrier density in the drift region. Both the aforementioned variations affect the spread of the electric field in the FLR edge termination regions. | SONG QingWen TANG XiaoYan HAN Chao YUAN Hao YANG Shuai He XiaoNing ZHANG YiMeng ZHANG YiMen ZHANG YuMing | 2019 | Science China(Technological Sciences)2019，62，7： | 1 |
| 20 | Surface profile measurement of moving objects by using an improved : phase-shifting Fourier transform profilometry 显示文摘 | Eryi Hu Yuming He | 2009 | Optics and Lasers inEngineering2009，47，1： | 1 |
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