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| 1 | H7N9 virulent mutants detected in chickens in China pose an increased threat to humans显示文摘 | Jianzhong Shi Guohua Deng Huihui Kong Chunyang Gu Shujie Ma Xin Yin Xianying Zeng Pengfei Cui Yan Chen Huanliang Yang Xiaopeng Wan Xiurong Wang Liling Liu Pucheng Chen Yongping Jiang Jinxiong Liu Yuntao Guan Yasuo Suzuki Mei Li Zhiyuan Qu Lizheng Guan Jinkai Zang Wenli Gu Shuyu Han Yangming Song Yuzhen Hu Zeng Wang Linlin Gu Wenyu Yang Libin Liang Hongmei Bao Guobin Tian Yanbing Li Chuanling Qiao Li Jiang Chengjun Li Zhigao Bu Hualan Chen | 2017 | Cell Research2017，27，12： | 70 |
| 2 | Structural insights into DndE from Escherichia coil B7A involved in DNA phosphorothioation modification显示文摘 | Wei Hu Chengkun Wang Jingdan Liang Tianlong Zhang Zhongpei Hu Zhijun Wang Wenxian Lan Fang Li Houming Wu Jianping Ding Geng Wu Zixin Deng Chunyang Cao | 2012 | Cell Research2012，22，7： | 7 |
| 3 | Study of stimulated Raman and Brillouin scattering in a finite interaction region under the convective instability condition显示文摘We discuss stimulated Raman scattering (SRS) and stimulated Brillouin scattering (SBS) under the convective instability condition with a one-dimensional three-wave interaction (3WI) model.Using linear theory,we deduce the temporal growth rate,gain exponent,and reflectivity of the backward scattered wave in a finite interaction region.We find that the growth rate is not only determined by the laser intensity and plasma density and temperature,but also related to the spatial gain.The length of the interaction region is important to the gain exponent and backscattering level.We simulate the developments and evolutions of SRS and SBS based on the 3WI equations.Our numerical results consist with the linear theory. | HAO Liang LIU ZhanJu ZHENG ChunYang XIANG Jiang FENG Wu HU XiaoYan LI Bin | 2012 | Chinese Science Bulletin2012，57，21： | 5 |
| 4 | Disaster Risk Science:A Geographical Perspective and a Research Framework显示文摘In this article,we recall the United Nations’30-year journey in disaster risk reduction strategy and framework,review the latest progress and key scientific and technological questions related to the United Nations disaster risk reduction initiatives,and summarize the framework and contents of disaster risk science research.The object of disaster risk science research is the'disaster system'consisting of hazard,the geographical environment,and exposed units,with features of regionality,interconnectedness,coupling,and complexity.Environmental stability,hazard threat,and socioeconomic vulnerability together determine the way that disasters are formed,establish the spatial extent of disaster impact,and generate the scale of losses.In the formation of a disaster,a conducive environment is the prerequisite,a hazard is the necessary condition,and socioeconomic exposure is the sufficient condition.The geographical environment affects local hazard intensity and therefore can change the pattern of loss distribution.Regional multi-hazard,disaster chain,and disaster compound could induce complex impacts,amplifying or attenuating hazard intensity and changing the scope of affected areas.In the light of research progress,particularly in the context of China,we propose a threelayer disaster risk science disciplinary structure,which contains three pillars(disaster science,disaster technology,and disaster governance),nine core areas,and 27 research fields.Based on these elements,we discuss the frontiers in disaster risk science research. | Peijun Shi Tao Ye Ying Wang Tao Zhou Wei Xu Juan Du Jing'ai Wang Ning Li Chongfu Huang Lianyou Liu Bo Chen Yun Su Weihua Fang Ming Wang Xiaobin Hu Jidong Wu Chunyang He Qiang Zhang Qian Ye Carlo Jaeger Norio Okada | 2020 | International Journal of Disaster Risk Science2020，11，4： | 4 |
| 5 | Scheme design of the CHANG'E-5T1 extended mission显示文摘Flight schemes for the CHANG'E-5T1 extended mission are investigated in this paper.In the flight scheme and trajectory design, the remaining propellant of the CHANG'E-5T1 mission is utilized. The CHANG'E-5T1 mission is firstly introduced with feasible flight goals derived based on the terminal trajectory and satellite status. The flight schemes are designed to include a lunar return and the libration points in the Sun-Earth/Moon and Earth-Moon systems, with an emphasis on the Earth-Moon triangle libration point thus far unexplored. Secondly, three schemes are proposed for the CHANG'E-5T1 extended mission with different flight goals. The direct libration point orbit transfer and injection method is adopted to solve the issue in the transfer trajectory design.Furthermore, an innovative concept is proposed to transfer from the Earth-Moon collinear libration point to the triangle point using the Sun-Earth/Moon libration point. Finally, the merits and drawbacks of the three schemes are discussed in terms of flight time, control energy and frequency, flight distance, and goal value. As a result, the scheme including a lunar return and the Earth-Moon L2 libration point is selected for the CHANG'E-5T1 extended mission. A flight to the Earth-Moon libration point is achieved, replicating the achievement of the ARTEMIS mission. | Lei LIU Chunyang HU | 2018 | Chinese Journal of Aeronautics2018，31，7： | 3 |
| 6 | Synthesis and characterization of BiFeO_3 nanotube arrays and Y-junction BiFeO_3 nanotubes显示文摘Multiferroic BiFeO3 (BFO) nanotube arrays (~100 nm in diameter and ~50 μm in length) were synthesized by the sol-gel method utilizing the anodic aluminum oxide (AAO) membrane technique. The micro-structure and chemical components of the BFO nanotubes were investigated using scanning electron microscopy (SEM), transmission electron microscopy (TEM) and X-ray photoelectron spectrometer (XPS). The BFO nanotubes exhibited polycrystalline microstructures. The novel Y-junction BFO nano-tubes were simultaneously fabricated. | LI ChunYang LIU Bing ZHAO JianPo WANG JiangFeng HU BinBin DU ZuLiang | 2009 | Chinese Science Bulletin2009，54，5： | 3 |
| 7 | Progress in octahedral spherical hohlraum study显示文摘In this paper,we give a review of our theoretical and experimental progress in octahedral spherical hohlraum study.From our theoretical study,the octahedral spherical hohlraums with 6 Laser Entrance Holes(LEHs)of octahedral symmetry have robust high symmetry during the capsule implosion at hohlraum-to-capsule radius ratio larger than 3.7.In addition,the octahedral spherical hohlraums also have potential superiority on low backscattering without supplementary technology.We studied the laser arrangement and constraints of the octahedral spherical hohlraums,and gave a design on the laser arrangement for ignition octahedral hohlraums.As a result,the injection angle of laser beams of 50°-60°was proposed as the optimum candidate range for the octahedral spherical hohlraums.We proposed a novel octahedral spherical hohlraum with cylindrical LEHs and LEH shields,in order to increase the laser coupling efficiency and improve the capsule symmetry and to mitigate the influence of the wall blowoff on laser transport.We studied on the sensitivity of the octahedral spherical hohlraums to random errors and compared the sensitivity among the octahedral spherical hohlraums,the rugby hohlraums and the cylindrical hohlraums,and the results show that the octahedral spherical hohlraums are robust to these random errors while the cylindrical hohlraums are the most sensitive.Up till to now,we have carried out three experiments on the spherical hohlraum with 2 LEHs on Shenguang(SG)laser facilities,including demonstration of improving laser transport by using the cylindrical LEHs in the spherical hohlraums,spherical hohlraum energetics on the SGIII prototype laser facility,and comparisons of laser plasma instabilities between the spherical hohlraums and the cylindrical hohlraums on the SGIII laser facility. | Ke Lan Jie Liu Zhichao Li Xufei Xie Wenyi Huo Yaohua Chen Guoli Ren Chunyang Zheng Dong Yang Sanwei Li Zhiwen Yang Liang Guo Shu Li Mingyu Zhang Xiaoying Han Chuanlei Zhai Lifei Hou Yukun Li Keli Deng Zheng Yuan Xiayu Zhan Feng Wang Guanghui Yuan Haijun Zhang Bobin Jiang Lizhen Huang Wei Zhang Kai Du Runchang Zhao Ping Li Wei Wang Jingqin Su Xuewei Deng Dongxia Hu Wei Zhou Huaiting Jia Yongkun Ding Wanguo Zheng Xiantu He | 2016 | Matter and Radiation at Extremes2016，1，1： | 2 |
| 8 | Static and modal analyzing for the working table components of a machining center in ANSYS显示文摘In this paper,modal analysis theory,equivalent dynamic model of the joint surface of assembly and identification methods of joint surface parameters are the main theories.Static and modal analysis of the working table components of the FM6324 machining center is done.The three-dimensional model of the working table components is established using Pro E at first,then static characteristics is obtained through ANSYS contact analysis;finally,the dynamic model is established in ANSYS,and its dynamic characteristics is obtained through ANSYS modal analysis. | XIA Lian HU Chunyang HAN Jiang | 2012 | Computer Aided Drafting,Design and Manufacturing2012，22，2： | 2 |
| 9 | Sex-specific association between coffee consumption and incident chronic kidney disease: a population-based analysis of 359,906 participants from the UK Biobank显示文摘Background:The risk for chronic kidney disease(CKD)is influenced by genetic predisposition,sex,and lifestyle.Previous research indicates that coffee is a potentially protective factor in CKD.The current study aims to investigate whether sex disparity exists in the coffee–CKD association,and whether genetic risk of CKD or genetic polymorphisms of caffeine metabolism affect this association.Methods:A total of 359,906 participants from the UK Biobank who were enrolled between 2006 and 2010 were included in this prospective cohort study,which aimed to estimate the hazard ratios for coffee intake and incident CKD using a Cox proportional hazard model.Allele scores of CKD and caffeine metabolism were additionally adjusted for in a subsample with qualified genetic data(n=255,343).Analyses stratified by genetic predisposition,comorbidities,and sex hormones were performed.Tests based on Bayesian model averaging were conducted to ascertain the robustness of the results.Results:Coffee was inversely associated with CKD in a dose-dependent manner.The effects of coffee did not differ across different strata of genetic risk for CKD,but were more evident among slower genetically predicted caffeine metabolizers.Significant sex disparity was observed(P value for interaction=0.013),in that coffee drinking was only associated with the risk reduction of CKD in females.Subgroup analysis revealed that testosterone and sex hormone-binding globulin(SHBG),but not estradiol,modified the coffee–CKD association.Conclusions:In addition to the overall inverse coffee–CKD association that was observed in the general population,we could also establish that a sex disparity existed,in that females were more likely to experience the benefit of the association.Testosterone and SHBG may partly account for the sex disparity. | Lei Tang Lina Yang Wenwen Chen Chunyang Li Yu Zeng Huazhen Yang Yao Hu Yuanyuan Qu Huan Song Xiaoxi Zeng Ping Fu | 2022 | Chinese Medical Journal2022，，12： | 2 |
| 10 | Polymyxin resistance caused by large-scale genomic inversion due to IS26 intramolecular translocation in Klebsiella pneumoniae显示文摘Polymyxin B and polymyxin E(colistin)are presently considered the last line of defense against human infections caused by multidrug-resistant Gram-negative organisms such as carbapenemase-producer Enterobacterales,Acinetobacter baumannii,and Klebsiella pneumoniae.Yet resistance to this last-line drugs is a major public health threat and is rapidly increasing.Polymyxin S2(S2)is a polymyxin B analogue previously synthesized in our institute with obviously high antibacterial activity and lower toxicity than polymyxin B and colistin.To predict the possible resistant mechanism of S2for wide clinical application,we experimentally induced bacterial resistant mutants and studied the preliminary resistance mechanisms.Mut-S,a resistant mutant of K.pneumoniae ATCC BAA-2146(Kpn2146)induced by S2,was analyzed by whole genome sequencing,transcriptomics,mass spectrometry and complementation experiment.Surprisingly,large-scale genomic inversion(LSGI)of approximately 1.1 Mbp in the chromosome caused by IS26mediated intramolecular transposition was found in Mut-S,which led to mgrB truncation,lipid A modification and hence S2resistance.The resistance can be complemented by plasmid carrying intact mgrB.The same mechanism was also found in polymyxin B and colistin induced drug-resistant mutants of Kpn2146(Mut-B and Mut-E,respectively).This is the first report of polymyxin resistance caused by IS26 intramolecular transposition mediated mgrB truncation in chromosome in K.pneumoniae.The findings broaden our scope of knowledge for polymyxin resistance and enriched our understanding of how bacteria can manage to survive in the presence of antibiotics. | Haibin Li Lang Sun Han Qiao Zongti Sun Penghe Wang Chunyang Xie Xinxin Hu Tongying Nie Xinyi Yang Guoqing Li Youwen Zhang Xiukun Wang Zhuorong Li Jiandong Jiang Congran Li Xuefu You | 2023 | Acta Pharmaceutica Sinica B2023，13，9： | 1 |
| 11 | Research and realization of resource cloud encapsulation in cloud manufacturing 显示文摘 | Zhang Ming Hu Chunyang | 2013 | International Journal of Computer Science Issues2013，10，1： | 1 |
| 12 | Simple and accurate quantifi- cation of quantum yield at the single-molecule/particle level显示文摘 | Hu Juan Zhang Chunyang | 2013 | Analytical Chemistry2013，85，4： | 1 |
| 13 | The investigation of DARC etch back in DRAM capacitor oxide mask opening显示文摘Opening the silicon oxide mask of a capacitor in dynamic random access memory is a critical process on a capacitive coupled plasma(CCP)etch tool.Three steps,dielectric anti-reflective coating(DARC)etch back,silicon oxide etch and strip,are contained.To acquire good performance,such as low leakage current and high capacitance,for further fabricating capacitors,we should firstly optimize DARC etch back.We developed some experiments,focusing on etch time and chemistry,to evalu-ate the profile of a silicon oxide mask,DARC remain and critical dimension.The result shows that etch back time should be con-trolled in the range from 50 to 60 s,based on the current equipment and condition.It will make B/T ratio higher than 70%mean-while resolve the DARC remain issue.We also found that CH_(2)F_(2) flow should be~15 sccm to avoid reversed CD trend and keep in-line CD. | Jianqiu Hou Zengwen Hu Kuowen Lai Yule Sun Bo Shao Chunyang Wang Xinran Liu Karson Liu | 2021 | Journal of Semiconductors2021，42，7： | 1 |
| 14 | Research of cloud manufacturing and resource encapsulation technology 显示文摘 | HU Chunyang WANG Yanwei ZHU Panfeng | 2011 | Applied Mechanics and Materials Information Technolo- gy for Manufacturing Systems II2011，5860，： | 1 |
| 15 | Re- search of cloud manufacturing and resource encapsulation technology显示文摘 | LI Chunquan HU Chunyang WANG Yanwei | 2011 | Applied Mechanics and Materials2011，5860，： | 1 |
| 16 | OBV(obscure vein),a C_(2)H_(2)zinc finger transcription factor,positively regulates chloroplast development and bundle sheath extension formation in tomato(Solanum lycopersicum)leaf veins显示文摘Leaf veins play an important role in plant growth and development,and the bundle sheath(BS)is believed to greatly improve the photosynthetic efficiency of C_(4) plants.The OBV mutation in tomato(Solanum lycopersicum)results in dark veins and has been used widely in processing tomato varieties.However,physiological performance has difficulty explaining fitness in production.In this study,we confirmed that this mutation was caused by both the increased chlorophyll content and the absence of bundle sheath extension(BSE)in the veins.Using genome-wide association analysis and map-based cloning,we revealed that OBV encoded a C_(2)H_(2) L domain class transcription factor.It was localized in the nucleus and presented cell type-specific gene expression in the leaf veins.Furthermore,we verified the gene function by generating CRISPR/Cas9 knockout and overexpression mutants of the tomato gene.RNA sequencing analysis revealed that OBV was involved in regulating chloroplast development and photosynthesis,which greatly supported the change in chlorophyll content by mutation.Taken together,these findings demonstrated that OBV affected the growth and development of tomato by regulating chloroplast development in leaf veins.This study also provides a solid foundation to further decipher the mechanism of BSEs and to understand the evolution of photosynthesis in land plants. | Jinghua Lu Chunyang Pan Xin Li Zejun Huang Jinshuai Shu Xiaoxuan Wang Xiaoxiao Lu Feng Pan Junling Hu Hui Zhang Wenyue Su Min Zhang Yongchen Du Lei Liu Yanmei Guo Junming Li | 2021 | Horticulture Research2021，8，1： | 1 |
| 17 | RFPose-OT:RF-based 3D human pose estimation via optimal transport theory显示文摘This paper introduces a novel framework,i.e.,RFPose-OT,to enable three-dimensional(3D)human pose estimation from radio frequency(RF)signals.Different from existing methods that predict human poses from RF signals at the signal level directly,we consider the structure difference between the RF signals and the human poses,propose a transformation of the RF signals to the pose domain at the feature level based on the optimal transport(OT)theory,and generate human poses from the transformed features.To evaluate RFPose-OT,we build a radio system and a multi-view camera system to acquire the RF signal data and the ground-truth human poses.The experimental results in a basic indoor environment,an occlusion indoor environment,and an outdoor environment demonstrate that RFPose-OT can predict 3D human poses with higher precision than state-of-the-art methods. | Cong YU Dongheng ZHANG ZhiWU Zhi LU Chunyang XIE Yang HU Yan CHEN | 2023 | Frontiers of Information Technology & Electronic Engineering2023，24，10： | 1 |
| 18 | Effect of chitosan/type I collagen/gelatin composites in biocompatibility and nerve repair显示文摘Chitosan, collagen I and gelatin were mixed in appropriate quantities to develop a new nerve repair material, with good arrangement and structure, as well as even aperture size. The composite material was sterilized by 60Co irradiation for 24 hours prior to implantation in the right thigh of rats following sciatic nerve damage. Results showed that the material was nontoxic to the kidneys and the liver, and did not induce an inflammatory response in the muscles. The composite material enhanced the recovery of sciatic nerve damage in rats. These experimental findings indicate that the composite material offers good biocompatibility and has a positive effect on injured nerve rehabilitation. | Qing Wang Xiaolei Yang Ming Ren Yulin Hu Qiang Chen Lei Xing Chunyang Meng Tiemei Liu | 2012 | Neural Regeneration Research2012，7，15： | 1 |
| 19 | A Key Management Scheme Based on Hypergraph for Fog Computing显示文摘Fog computing is a new paradigm supporting the stringent requirements of mobility applications by bridging cloud computing and smart devices. Since the smart devices may be deployed in dynamic areas where are out of strict monitoring and protection, fog computing requires security protections to ensure confidentiality and integrity. In this article, to deal with security requirements and considering the distinctive features, a key management based on hypergraph schemed is designed. Firstly, based on the key hypergraph, the three hierarchy architecture of fog computing is divided into two subnetworks. Furthermore, each key management process of both two subnetworks is designed to satisfy the operational and security requirements of fog computing. Finally, the performance evaluation and numerical simulation have been provided to validate the proposed scheme. | Zhi Li Yanzhu Liu Di Liu Chunyang Li Wei Cui Guanglin Hu | 2018 | China Communications2018，15，11： | 0 |
| 20 | Two-dimensional tin diselenide nanosheets pretreated with an alkaloid for near-and mid-infrared ultrafast photonics显示文摘Two-dimensional(2D)tin diselenide(SnSe2),a novel layered material with excellent optical and electronic properties,has been extensively investigated in various promising applications,including photodetectors,optical switching,and ultrafast photonics.In this work,SnSe2 nanosheets have been obtained after pretreatment in an alkaloid,exhibiting high optical absorption and electron-enriched properties.Besides,the performances of the prepared SnSe2 in near-infrared(NIR)and mid-infrared(MIR)ultrafast photonics are presented.Notably,by employing the SnSe2-deposited microfiber device as a saturable absorber(SA)exhibiting typical nonlinear optical absorption properties,stable ultrashort pulses and rogue waves are realized in an erbium-doped fiber laser.Furthermore,the SnSe2-deposited SA device is also applied to a thulium-doped fiber laser to achieve stable ultrashort pulses.This study indicates that SnSe2 is expected to be a suitable candidate for ultrafast fiber lasers in the NIR and MIR regions. | Zhenhong Wang Bin Zhang Bing Hu Zhongjun Li Chunyang Ma Yu Chen Yufeng Song Han Zhang Jun Liu Guohui Nie | 2020 | Photonics Research2020，8，11： | 0 |
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