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| 1 | Experimental Investigation into Characteristics of Plasma Aerodynamic Actuation Generated by Dielectric Barrier Discharge显示文摘This article carries out synthetic measurements and analysis of the characteristics of the asymmetric surface dielectric barrier discharge plasma aerodynamic actuation.The rotational and vibrational temperatures of an N2 (C3Пu) molecule are measured in terms of the optical emission spectra from the N2 second positive system.A simplified collision-radiation model for N2(C) and N2+(B) is established on the basis of the ratio of emission intensity at 391.4 nm to that at 380.5 nm and the ratio of emission intensity at 371.1 nm to that at 380.5 nm for calculating temporal and spatial averaged electron temperatures and densities.Under one atmosphere pressure,the electron temperature and density are on the order of 1.6 eV and 1011cm-3 respectively.The body force induced by the plasma aerodynamic actuation is on the order of tens of mN while the induced flow velocity is around 1.3m/s.Starting vortex is firstly induced by the actuation;then it develops into a near-wall jet,about 70 mm downstream of the actuator.Unsteady plasma aerodynamic actuation might stimulate more vortexes in the flow field.The induced flow direction by nanosecond discharge plasma aerodynamic actuation is not parallel,but vertical to the dielectric layer surface. | Wu Yun Li Yinghong Jia Min Song Huimin Su Changbing Pu Yikang | 2010 | Chinese Journal of Aeronautics2010，23，1： | 20 |
| 2 | Synergistic therapy of magnetism-responsive hydrogel for soft tissue injuries显示文摘Soft tissue injury is very common and associated with pain,tissue swelling and even malformation if not treated on time.Treating methods include cryotherapy,electrical therapy,ultrasound therapy and anti-inflammatory drug,but none of them is completely satisfying.In this work,for a better therapeutic effect,drug therapy and pulsed electromagnetic field(PEMF)therapy were combined.We constructed a drug delivery system using the tetra-PEG/agar hydrogel(PA).By incorporating Fe3O4 NPs into the hydrogel network,a magnetism-responsive property was achieved in the system.The cytotoxicity and in vivo study showed a good biocompatibility of the PA/Fe3O4 hydrogel.A magnetism-controlled release was attained by the incorporation of Fe3O4.Finally,in vivo study showed a better performance of the DS-loaded PA/Fe3O4 compared with the commercially available DS ointment regarding the recovery of the injured soft tissue.Therefore,this magnetism-responsive hydrogel may represent a promising alternative to treat soft tissue injury. | Lining Zhang Xiuqin Zuo Shengjie Li Mi Sun Huimin Xie Kai Zhang Jikun Zhou Liyun Che Junxuan Ma Zishan Jia Fei Yang | 2019 | Bioactive Materials2019，4，1： | 7 |
| 3 | A water-soluble fluorescence resonance energy transfer probe for hypochlorous acid and its application to cell imaging显示文摘A water-soluble fluorescence resonance energy transfer (FRET) probe for hypochlorous acid (HOCl), dansyl rhodamine B piperazinoacetohydrazide, was designed, synthesized and characterized. The dansyl moiety in the probe acted as a FRET donor and the rhodamine moiety acted as a FRET acceptor. The two moieties were connected by a HOCl-cleavable active bond, and cleavage of this linker decreased the FRET efficiency and increased the fluorescence intensity of the donor at 501 nm. The water solubility of the probe was improved compared with other probes by introduction of the cationic rhodamine fluorophore. As a result, the probe could be used to detect HOCl in aqueous biosystems with a linear range of 2-10 mol/L and a detection limit of 80 nmol/L (signal- to-noise = 3). The probe was successfully applied to fluorescence imaging of HOCl in HeLa cells. | JIA Jia MA HuiMin | 2011 | Chinese Science Bulletin2011，56，31： | 3 |
| 4 | Substitute of Expensive Pt with Improved Electrocatalytic Performance and Higher Resistance to CO Poisoning for Methanol Oxidation: the Case of Synergistic Pt-Co_3O_4 Nanocomposite显示文摘In this paper, Pt-Co_3O_4 nanocomposite was synthesized by a sol gel process combined with electrodeposition method. Its electrocatalytic activity towards methanol oxidation was investigated at room temperature using cyclic voltammetry(CV), electrochemical impedance spectroscopy(EIS) and current density time curve. It is found that the resultant Pt-Co_3O_4 catalysts with minute amount of Pt exhibite attractive electrocatalytic activity for methanol oxidation reaction(MOR) but with a high resistance CO poisoning due to the synergistic effects from Pt and Co_3O_4. Together with the low manufacturing cost of Co_3O_4, the reported nanostructured Pt-Co_3O_4 catalyst is expected to be a promising electrode material for direct methanol fuel cells(DMFC). | Hongxiao Zhao Zhi Zheng Jing Li Huimin Jia Ka-wai Wong Yidong Zhang Woon Ming Lau | 2013 | Nano-Micro Letters2013，5，4： | 3 |
| 5 | Rapid isolation and immune profiling of SARS-CoV-2 specific memory B cell in convalescent COVID-19 patients via LIBRA-seq显示文摘B cell response plays a critical role against SARS-CoV-2 infection.However,little is known about the diversity and frequency of the paired SARS-CoV-2 antigen-specific BCR repertoire after SARS-CoV-2 infection.Here,we performed single-cell RNA sequencing and VDJ sequencing using the memory and plasma B cells isolated from five convalescent COVID-19 patients,and analyzed the spectrum and transcriptional heterogeneity of antibody immune responses.Via linking BCR to antigen specificity through sequencing(LIBRA-seq),we identified a distinct activated memory B cell subgroup(CD11c^(high) CD95^(high))had a higher proportion of SARS-CoV-2 antigen-labeled cells compared with memory B cells.Our results revealed the diversity of paired BCR repertoire and the non-stochastic pairing of SARS-CoV-2 antigen-specific immunoglobulin heavy and light chains after SARS-CoV-2 infection.The public antibody clonotypes were shared by distinct convalescent individuals.Moreover,several antibodies isolated by LIBRA-seq showed high binding affinity against SARS-CoV-2 receptor-binding domain(RBD)or nucleoprotein(NP)via ELISA assay.Two RBD-reactive antibodies C14646P3S and C2767P3S isolated by LIBRA-seq exhibited high neutralizing activities against both pseudotyped and authentic SARS-CoV-2 viruses in vitro.Our study provides fundamental insights into B cell response following SARS-CoV-2 infection at the single-cell level. | Bing He Shuning Liu Yuanyuan Wang Mengxin Xu Wei Cai Jia Liu Wendi Bai Shupei Ye Yong Ma Hengrui Hu Huicui Meng Tao Sun Yanling Li Huanle Luo Mang Shi Xiangjun Du Wenjing Zhao Shoudeng Chen Jingyi Yang Haipeng Zhu Yusheng Jie Yuedong Yang Deyin Guo Qiao Wang Yuwen Liu Huimin Yan Manli Wang Yao-Qing Chen | 2021 | Signal Transduction and Targeted Therapy2021，6，6： | 2 |
| 6 | Hollow PtNi alloy nanospheres with enhanced activity and methanol tolerance for the oxygen reduction reaction显示文摘为氧减小反应(ORR ) 的活跃、甲醇容忍的阴极 electrocatalysts 的发展为加速直接甲醇燃料房间(DMFC ) 的商业生存能力是极其重要的。在这个工作,我们在场为氰化物(CN ) 的灵巧的合成的一条有效、没有模板的线路有用在房间温度的一个简单 cyanogel 减小方法的高 alloying 度的 -functionalized PtNi 空 nanospheres (PtNi@CN HNS ) 。物理并且 PtNi@CN HNS 的 electrocatalytic 性质被各种各样的物理、电气化学的技术调查。当与商业磅黑色相比,并且这样他们为 DMFC 正在答应阴极 electrocatalysts,显著地展出的 PtNi@CN HNS 为 ORR 提高了 electrocatalytic 活动,耐久性,和特别甲醇忍耐。 | Huimin Liu Xinyu Liu Yumei Li Yufeng Jia Yawen Tang Yu Chen | 2016 | Nano Research2016，9，11： | 2 |
| 7 | Terminal Precambrian Palaeogeographic Framework of China显示文摘The original locations and relationships of four plates within the mainland of China from 800 to 600 Ma during the terminal Precambrian were reconstructed based on the palaeomagnetic and geological data. The Tarim, Yangtze and Cathaysian plates were once linked (in 800-700 Ma) and located in the same low-latitude zone of the northern hemisphere. But later, in 700-600 Ma, the Tarim plate was separated from the Yangtze-Cathaysian plate. The Sino-Korean plate was always far away from the Yangtze plate, both being separated by oceanic crust, and lay in the high-latitude zone of the northern hemisphere.The above-mentioned palaeogeographic framework directly led to complete differences in respect to distribution of low-latitude glaciation, sedimentary facies, palaeoclimate, palaeobiogeography and stratigraphic sections between the North and South China domains during the terminal Precambrian. | Qiao Xiufu, Ma Lifang Geological Institute, CAGS, Beijing, and Zhang Huimin Tianjin Institute of Geology and Mineral Resources, CAGS, Tianjin Jia Zhongpeng | 1989 | Acta Geologica Sinica(English Edition)1989，63，2： | 2 |
| 8 | Nonaqueous sol-gel synthesis and growth mechanism of single crystalline TiO2 nanorods with high photocatalytic activity 显示文摘 | JIA Huimin ZHENG Zhi ZHAO Hongxiao | 2009 | Mater Res Bull2009，44，： | 1 |
| 9 | A case-control study for the association between Change in weight,Family history and hypertension at different ages显示文摘 | Wu Guanglin Yang Huimin Qi Xiuying Jia Zhenlin | 2001 | Asia-Pacific Houranl of Public health2001，13，2： | 1 |
| 10 | Disposition of Flavonoids via Enteric Recycling: Enzyme- Transporter coupling Affects Metabolism of Biochanin A and Formononetin and Excretion of Their phase II conjugates显示文摘 | Xiaobin Jia Jun Chen Huimin Lin | 2004 | The Journal of Pharmacology and Experimental Therapeutics2004，310，： | 1 |
| 11 | Potential Treatment of COVID-19 with Traditional Chinese Medicine: What Herbs Can Help Win the Battle with SARS-CoV-2?显示文摘Traditional Chinese medicine(TCM)has been successfully applied worldwide in the treatment of coronavirus disease 2019(COVID-19),which is caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).However,the pharmacological mechanisms underlying this success remain unclear.Hence,the aim of this review is to combine pharmacological assays based on the theory of TCM in order to elucidate the potential signaling pathways,targets,active compounds,and formulas of herbs that are involved in the TCM treatment of COVID-19,which exhibits combatting viral infections,immune regulation,and amelioration of lung injury and fibrosis.Extensive reports on target screening are elucidated using virtual prediction via docking analysis or network pharmacology based on existing data.The results of these reports indicate that an intricate regulatory mechanism is involved in the pathogenesis of COVID-19.Therefore,more pharmacological research on the natural herbs used in TCM should be conducted in order to determine the association between TCM and COVID-19 and account for the observed therapeutic effects of TCM against COVID-19. | Lin Li Yuzheng Wu Jiabao Wang Huimin Yan Jia Lu Yu Wang Boli Zhang Junhua Zhang Jian Yang Xiaoying Wang Min Zhang Yue Li Lin Miao Han Zhang | 2022 | Engineering2022，，12： | 1 |
| 12 | Preparation of po- rous nylon 6 fiber via electrospinning显示文摘 | ZHANG Huimin ZHANG Li JIA Qingxiu | 2015 | Polymer Engineering and Sci- ence2015，55，5： | 1 |
| 13 | Highly efficient gene editing and single cell analysis of hematopoietic stem/progenitor cells from X-linked sideroblastic anemia patients显示文摘Dear Editor,X-linked sideroblastic anemia(XLSA),which is the most common genetic form of congenital sideroblastic anemia,is typically characterized by reduced heme synthesis and the presence of bone marrow(BM)ring sideroblasts containing pathologic iron deposits in the mitochondria. | Riguo Fang Jingliao Zhang Huihui Yang Jia Shi Huimin Zeng Xiaofan Zhu Dong Wei Pengfei Yuan Tao Cheng Yingchi Zhang | 2021 | Signal Transduction and Targeted Therapy2021，6，8： | 1 |
| 14 | Geology,Mineralogy,and Isotopic Characteristics of the Zhonghe Ag-Pb-Zn Deposit,Western Henan Province,Central China显示文摘Located in Luoning County,western Henan Province,Central China,the Zhonghe Ag-Pb-Zn ore field,is a newly discovered deposit in the Xiaoshan District.Ore bodies controlled by NNW Faults occur as veins within the Paleoproterozoic Xiong’er Group or the Early Cretaceous porphyritic granite.Given that the Zhonghe deposit has been covered by thick Quaternary sediments,the paragenetic mineral assemblage was determined mainly by microscopic observations,including the quartzsiderite-pyrite alteration (StageⅠ),polymetallic sulfide precipitation (StageⅡ),silver mineralization(Stage Ⅲ),and quartz-carbonate stage (StageⅣ).The host minerals for silver are diverse,such as freibergite,pyrargyrite,polybasite,argyrodite,canfieldite,argentite,and native silver,whereas those for Pb and Zn are galena and sphalerite,respectively.In order to constrain the ore-forming components of the Zhonghe deposit,a combined in-situ analysis was conducted on represented sulfides from StageⅡand Stage Ⅲ.In-situ δ^(34)S values of the analyzed sulfides,including the pyrite,chalcopyrite,sphalerite,and galena,display a relatively narrow range (0.90‰-5.0‰),which is close to magmatic sulfur source.The ^(206)Pb/^(204)Pb and^(207)Pb/^(204)Pb ratios show a narrow range (17.140-17.360 and 15.385-15.490),whereas the ^(208)Pb/^(204)Pb ratios exhibit a broad variation (36.601-37.943),indicating a contamination of the Xiong’er Group.Synthesis of geochronological and geochemical data from the Xiaoshan District,we contend that the ore-forming materials of the Zhonghe Ag-Pb-Zn deposit are originated from the lower crust,which has presumably been influenced by the large-scale lithospheric delamination of the eastern North China Craton during the Early Cretaceous.In consideration of the geological setting,mineralogy,and geochemical compositions,we suggest that the Zhonghe Ag-Pb-Zn deposit is characterized as intermediate sulfidation type epithermal deposit,and may be a potential exploration target for porphyry Mo-Cu deposits. | Jiannan Xu Changqian Ma Shuo Yin Yunzhen Chang Huimin Jia Zhongjie Wang Liangliang Shi | 2022 | Journal of Earth Science2022，33，1： | 1 |
| 15 | Oxygen vacancy-mediated WO_(3) phase junction to steering photogenerated charge separation for enhanced water splitting显示文摘Effective charge separation and transfer is deemed to be the contributing factor to achieve high photoelectrochemical(PEC)water splitting performance on photoelectrodes.Building a phase junction structure with controllable phase transition of WO_(3) can further improve the photocatalytic performance.In this work,we realized the transition from orthorhombic to monoclinic by regulating the annealing temperatures,and constructed an orthorhombic–monoclinic WO_(3)(o-WO_(3)/m-WO_(3))phase junction.The formation of oxygen vacancies causes an imbalance of the charge distribution in the crystal structure,which changes the W–O bond length and bond angle,accelerating the phase transition.As expected,an optimum PEC activity was achieved over the o-WO_(3)/m-WO_(3) phase junction in WO_(3)-450 photoelectrode,yielding the maximum O_(2) evolution rate roughly 32 times higher than that of pure WO_(3)-250 without any sacrificial agents under visible light irradiation.The enhancement of catalytic activity is attributed to the atomically smooth interface with a highly matched lattice and robust built-in electric field around the phase junction,which leads to a less-defective and abrupt interface and provides a smooth interfacial charge separation and transfer path,leading to improved charge separation and transfer efficiency and a great enhancement in photocatalytic activity.This work strikes out on new paths in the formation of an oxygen vacancy-induced phase transition and provides new ideas for the design of catalysts. | Huimin LI Qianqian SHEN Han ZHANG Jiaqi GAO Husheng JIA Xuguang LIU Qi LI Jinbo XUE | 2022 | Journal of Advanced Ceramics2022，11，12： | 1 |
| 16 | Development of simple repeat(SSR)markers from a genome survey of Chinese bayberry(Myrica rubra)显示文摘 | JIAO Yun JIA Huimin LI Xiongwei CHAI Mingliang JIA Huijuan CHEN Zhe WANG Guoyun CHAI Chunyan Eric van deWeg GAO Zhongshan | 2012 | BMC Genomics2012，13，： | 1 |
| 17 | Development of 107 SSRs markersfrom whole genome shotgun sequences of Chinese bayberry(Myrica rubra)and their application in seedling identification显示文摘 | JIA Huimin SHEN Yutong WANG Guoyun DONG Xiao DUFang LIANG Senmiao ZHOU Chaochao JIA Huijuan MAOWeihua GAO Zhongshan | 2014 | Jour-nal of Zhejiang University-Science Biomedicine&Biotechnolo-gy2014，15，11： | 1 |
| 18 | A complete symbolic bisimulation for full applied pi calculus 显示文摘 | Liu Jia Lin Huimin | 2012 | Theoretical Computer Science2012，458，： | 1 |
| 19 | The influence of adsorption and desorption of cadmium in soil and its components research into显示文摘 | Zhang Huimin Xu Minggang Long Jia | 2005 | Journal of Agricultural Environment Science2005，，： | 1 |
| 20 | A selective and stepwise aggregation of a new fluorescent probe for dinitrate explosive differentiation by self-adaptive host-guest interaction显示文摘Nitrate explosive is hard to detect due to lack of aromatic ring and weak interaction with fluorescence probe.More challenging is even to differentiate the dinitrates with multiple nitrate explosives based on photo induced electron transfer or aggregation caused fluorescence change mechanism.A highly selective dinitrate explosive probe was designed based on a new strategy-stepwise aggregation of multiple anchored fluorene dimer 8Py-2 F.Compared with its monomer counterpart 2Py-F,8Py-2 F showed a selective and stepwise fluorescence quenching to dinitrate explosives-ethylene glycol(EGDN)and triethylene glycol dinitrate(TEGDN).The limits of detection(LODs)are 2.72μM for TEGDN and 0.46μM for EGDN,which is three orders of magnitude lower than those of 2Py-F.The stepwise quenching process is well matched with the stepwise aggregation process as evidence by scanning electron microscopy(SEM).Nuclear magnetic resonance(NMR)and quantum chemical calculation proved the interaction force between the dinitrate and 8Py-2 F is hydron bonding interaction,and interaction distance is far less than that of the multiple nitrates coming from the flexibility of the chain and steric hinderance,which resulted in a self-adaptive interaction and higher selectivity.The new strategy is beneficial for the differentiation of the chemicals with similar energy level which is difficult to realize via other method,and the new method provides fluorometric probe for dinitrate explosive detection and makes it an ideal candidate for chemical detection and analysis in public safety and environmental monitoring. | Jinlan Jia Wei Xu Yaguo Yu Yanyan Fu Qingguo He Huimin Cao Jiangong Cheng | 2020 | Science China Chemistry2020，63，1： | 1 |
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