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| 1 | Active corrosion protection of super-hydrophobic corrosion inhibitor intercalated Mg-Al layered double hydroxide coating on AZ31 magnesium alloy显示文摘Magnesium alloys,the advanced lightweight structural materials,have been successfully applied in the manufacturing field.Unfortunately,their poor corrosion resistance restrains the potential wide applications.In this work,anti-corrosion coatings were fabricated via the insitu growth of the corrosion inhibitors intercalated magnesium-aluminum layered double hydroxide(Mg-Al LDH)on AZ31 magnesium alloy and then post-sealing it by a super-hydrophobic coating.SEM,XRD,EDS,FTIR,XPS and contact angle test were conducted to analyze physical/chemical features of these coatings.Potentiodynamic polarization curves and electrochemical impedance spectroscopy were recorded to assess the anti-corrosion performance of prepared coatings.Surprisingly,Mg-Al LDH with molybdate intercalation and lauric acid modification achieves the excellent corrosion inhibition performance(99.99%)due to the multicomponent synergistic effect such as the physical protection of Mg-Al LDH,the corrosion inhibition of molybdate and super-hydrophobic properties of lauric acid.This work presents a scientific perspective and novel design philosophy to fabricate the efficient anti-corrosion coating to protect magnesium alloys and then expand their potential applications in other field. | Xin Wang Chuan Jing Yuxiang Chen Xiushuang Wang Gang Zhao Xing Zhang Liang Wu Xiaoying Liu Biqin Dong Yuxin Zhang | 2020 | Journal of Magnesium and Alloys2020，8，1： | 20 |
| 2 | Present status and development on biological nitrogen fixation research in China显示文摘This presentation introduces the advances inbiological nitrogen fixation research abroad, in particular,describes the great progress and achievements on itsresearch in China as follows: collection of rhizobial resources and establishment of the largest database of Rhizobium inChina, correction and development of Rhizobium taxonomy in international; discovery of a couple of nif genes,identification and unification of linkage among the nif gene operons of Klebsiella pneumoniae, finding of regulative mechanism of positive regulation nif gene and its sensitivity to oxygen, temperature; finding of the activity of nodulation gene nodD3 product in Sinorhizobium meliloti which is notcontrolled by flavonoid produced from its host alfalfa;finding of the association between expression of genes coding the products for carbon utilization and nitrogen metabolism and their regulations; chemical synthesis of nodulationfactor of Sinorhizobium meliloti; constructions of engineered nitrogen fixers and utilization in practice based on theresearch of gene expression and regulation; chemicalsimulation of the structure and function of nitrogenase and bringing forward the model of nitrogenase active center for the first time in international and synthesis of modelcompounds which were paid attention by colleagues abroad. Finally, the development of nitrogen fixation research inChina in future has been put forward, suggesting that the nifgene regulation and its role in providing crops with nitrogen element, signal transduction and molecular interactions between Rhizobium and legume, coupling between carbonand nitrogen metabolisms, nitrogen fixation andphotosynthesis, and functional genomics of nitrogen-fixing nodule symbiosis, etc., would be actively worked on. | SHEN Shihua & JING Yuxiang Key Laboratory of Photosynthesis and Plant-Environment MolecularPhysiology, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China | 2003 | Chinese Science Bulletin2003，48，10： | 5 |
| 3 | ACBD3 is required for FAPP2 transferring glucosylceramide through maintaining the Golgi integrity显示文摘Glycosphingolipid (GSL) metabolism is involved in various physiological processes, including all major cell signaling pathways, and its dysregulation is linked to some diseases. The four-phosphate adaptor protein FAPP2-mediated glucosylceramide (GlcCer) transport for complex GSL synthesis has been studied extensively. However, the molecular machinery of FAPP2 as a GlcCer-transferring protein remains poorly defined. Here, we identify a Golgi-resident protein, acyl-coenzyme A binding domain containing 3 (ACBD3), as an interacting partner of FAPP2. We find that ACBD3 knockdown leads to dramatic Golgi fragmentation, which subsequently causes FAPP2 dispersal throughout the cytoplasm and a decreased localization at trans-Golgi network. The further quantitative Upidomic analysis indicates that ACBD3 knockdown triggers abnormal sphingolipid metabolism. Interestingly, the expression of siRNA-resistant full-length ACBD3 can rescue these defects caused by ACBD3 knockdown. These data reveal critical roles for ACBD3 in maintaining the integrity of Golgi morphology and cellular sphingolipid homeostasis and establish the importance of the integrated Golgi complex for the transfer of GlcCer and complex GSL synthesis. | Jing Liao Yuxiang Guan Wei Chen Can Shi Dongdong Yao Fengsong Wang Sin Man Lam Guanghou Shui Xinwang Cao | 2019 | Journal of Molecular Cell Biology2019，11，2： | 3 |
| 4 | miR-34 is associated with poor prognosis of patients with gallbladder cancer through regulating telomere length in tumor stem cells显示文摘 | Ke Jin Yonghua Xiang Jing Tang Guangchun Wu Junwei Li Huaichun Xiao Chunwang Li Yuxiang Chen Jingfeng Zhao | 2014 | Tumor Biology2014，，2： | 1 |
| 5 | MicroRNAs‐372/373 promote the expression of hepatitis B virus through the targeting of nuclear factor I/B显示文摘 | Hongyan Guo Haiying Liu Keith Mitchelson Huiying Rao Mingyong Luo Lan Xie Yimin Sun Liang Zhang Ying Lu Ruyu Liu Aihui Ren Shuai Liu Shaozhen Zhou Jiye Zhu Yuxiang Zhou Ailong Huang Lai Wei Yong Guo Jing Cheng | 2011 | Hepatology2011，，3： | 1 |
| 6 | An invasive zone in human liver cancer identified by Stereo-seq promotes hepatocyte–tumor cell crosstalk,local immunosuppression and tumor progression显示文摘Dissecting and understanding the cancer ecosystem,especially that around the tumor margins,which have strong implications for tumor cell infiltration and invasion,are essential for exploring the mechanisms of tumor metastasis and developing effective new treatments.Using a novel tumor border scanning and digitization model enabled by nanoscale resolution-SpaTial Enhanced REsolution Omics-sequencing(Stereo-seq),we identified a 500µm-wide zone centered around the tumor border in patients with liver cancer,referred to as“the invasive zone”.We detected strong immunosuppression,metabolic reprogramming,and severely damaged hepatocytes in this zone.We also identified a subpopulation of damaged hepatocytes with increased expression of serum amyloid A1 and A2(referred to collectively as SAAs)located close to the border on the paratumor side.Overexpression of CXCL6 in adjacent malignant cells could induce activation of the JAK-STAT3 pathway in nearby hepatocytes,which subsequently caused SAAs’overexpression in these hepatocytes.Furthermore,overexpression and secretion of SAAs by hepatocytes in the invasive zone could lead to the recruitment of macrophages and M2 polarization,further promoting local immunosuppression,potentially resulting in tumor progression.Clinical association analysis in additional five independent cohorts of patients with primary and secondary liver cancer(n=423)showed that patients with overexpression of SAAs in the invasive zone had a worse prognosis.Further in vivo experiments using mouse liver tumor models in situ confirmed that the knockdown of genes encoding SAAs in hepatocytes decreased macrophage accumulation around the tumor border and delayed tumor growth.The identification and characterization of a novel invasive zone in human cancer patients not only add an important layer of understanding regarding the mechanisms of tumor invasion and metastasis,but may also pave the way for developing novel therapeutic strategies for advanced liver cancer and other solid tumors. | Liang Wu Jiayan Yan Yinqi Bai Feiyu Chen Xuanxuan Zou Jiangshan Xu Ao Huang Liangzhen Hou Yu Zhong Zehua Jing Qichao Yu Xiaorui Zhou Zhifeng Jiang Chunqing Wang Mengnan Cheng Yuan Ji Yingyong Hou Rongkui Luo Qinqin Li Liang Wu Jianwen Cheng Pengxiang Wang Dezhen Guo Waidong Huang Junjie Lei Shang Liu Yizhen Yan Yiling Chen Sha Liao Yuxiang Li Haixiang Sun Na Yao Xiangyu Zhang Shiyu Zhang Xi Chen Yang Yu Yao Li Fengming Liu Zheng Wang Shaolai Zhou Huanming Yang Shuang Yang Xun Xu Longqi Liu Qiang Gao Zhaoyou Tang Xiangdong Wang Jian Wang Jia Fan Shiping Liu Xinrong Yang Ao Chen Jian Zhou | 2023 | Cell Research2023，33，8： | 1 |
| 7 | Effect of harvest date on shearing force of maize stems 显示文摘 | Yuxiang Chen Jing Chen Yufen Zhang | 2007 | Livestock Science2007，111，： | 1 |
| 8 | Contamination assessment of Copper, Lead, Zinc, Manganese and Nickel in street dust of Baoji, NW China显示文摘 | Xinwei Lu Lijun Wang Kai Lei Jing Huang Yuxiang Zhai | 2009 | Journal of Hazardous Materials2009，161，： | 1 |
| 9 | NO 2 -sensing properties of porous WO 3 gas sensor based on anodized sputtered tungsten thin film显示文摘 | Jing Zeng Ming Hu Weidan Wang Huiqing Chen Yuxiang Qin | 2011 | Chemical2011，，1： | 1 |
| 10 | Formation of Nanoliter Droplets in a Confined Microfluidic T - Shaped Junc- tion: Formation Time and Droplet Volume 显示文摘 | Yuxiang Zhang Jing Fan Liqiu Wang | 2009 | Current Nano- science2009，，5： | 1 |
| 11 | Burn patients’ experience of pain management: A qualitative study显示文摘 | Li Yuxiang Zhou Lingjun Tang Lu Liu Mengjie Ming Xing Shen Fengping Cui Jing Meng Xianli Zhao Jijun | 2011 | Burns2011，，2： | 1 |
| 12 | Whole‐genome microRNA expression profiling identifies a 5‐microRNA signature as a prognostic biomarker in Chinese patients with primary glioblastoma multiforme显示文摘 | Wei Zhang Jing Zhang Wei Yan Gan You Zhaoshi Bao Shouwei Li Chunsheng Kang Chuanlu Jiang Yongping You Yuxiang Zhang Clark C. Chen Sonya Wei Song Tao Jiang | 2012 | Cancer2012，，4： | 1 |
| 13 | Research and applications of biochip technologies显示文摘Biochip as a new research field has enjoyed its rapid development in the past 10 years. Using microfabrication technology, thousands or hundred thousands of biological molecules can be assembled on a centimeter square microchip. Those chip-based devices can be used to analyze mutations, antigens, cells, etc. Compared with the traditional analytical instruments, chip-based micro total analytical systems have many advantages, such as reduced size, lower consumption of both reagents and energy contamination-free, etc. Biochip technology is believed to revolutionize the future research in life sciences, disease diagnosis, drug discovery forensic sciences and outer space exploitation in the coming | XU Junquan HE Xuezhong ZHOU Yuxiang LIU Litian CHENG Jing | 2000 | Chinese Science Bulletin2000，45，2： | 1 |
| 14 | Contamination assessment of copper, lead, zinc, manganese and nickel in street dust of Baoji, NW China显示文摘 | Xinwei Lu Lijun Wang Kai Lei Jing Huang Yuxiang Zhai | 2008 | Journal of Hazardous Materials2008，，2： | 1 |
| 15 | Contamination assessment of mercury and arsenic in roadway dust from Baoji, China显示文摘 | Xinwei Lu Loretta Y. Li Lijun Wang Kai Lei Jing Huang Yuxiang Zhai | 2009 | Atmospheric Environment2009，，15： | 1 |
| 16 | Construction of Armored RNA Containing Long-Size Chimeric RNA by Increasing the Number and Affinity of the Pac Site in Exogenous RNA and Sequence Coding Coat Protein of the MS2 Bacteriophage显示文摘 | Wei Baojun Wei Yuxiang Zhang Kuo Yang Changmei Wang Jing Xu Ruihuan Zhan Sien Lin Guigao Wang Wei Liu Min Wang Lunan Zhang Rui Li Jinming | 2008 | Intervirology2008，，2： | 1 |
| 17 | Effect of harvest date on shearing force of maize stems 显示文摘 | Yuxiang Chen Jing Chen Yufen Zhang | 2007 | Livestock Science2007，111，： | 1 |
| 18 | Proteomics approach to identify wound-response related proteins from rice leaf sheath显示文摘 | Shihua Shen Yuxiang Jing Tingyun Kuang | 2003 | Proteomics2003，，3： | 1 |
| 19 | The Development Roadmap of Direct Current Buildings(2020-2030)(Ⅱ)显示文摘2.1Development background2.1.1Greenhouse gas emission reduction is imminent Climate change is one of the most severe global challenges.China has made a solemn commitment to the international community at the national level to reach the peak of carbon dioxide emissions around 2030 and strive to reach the peak as soon as possible[30]. | Jiang Yi Hao Bin Li Yutong Ma Zhao Tong Yibin Kang Jing Li Yemao Pan Wenyu Lu Yuanyuan Zhao Yuming Shen Yuxiang Zhang Ning Zhao Jinbin Zhao Zhigang Chen Wenbo Wang Dawei Hou Enzhe | 2021 | 建筑节能(中英文)2021，49，9： | 0 |
| 20 | Solvent field regulated superhalogen in pure and doped gold cluster anions显示文摘Condensed-phase synthesis of atomically precise clusters has become a vital branch of cluster science,where solvents are indispensable in the synthesis process.Herein,by employing the density functional theory(DFT)calculations and molecular dynamics(MD)simulations,we demonstrated that polar solvents not only provide an important environment to stabilize clusters,but they can also dramatically alter the electronic property of cluster anions forming novel superhalogen anions.Such a regulation effect was first verified in small model gas-phase pure and doped gold cluster anions,which was further evidenced in a real experimentally synthesized Au18 nanocluster.Different solvation models reveal that the solvent field,which is a noninvasive methodology different from conventional electron-counting rules,can be considered as a novel external field to remarkably increase the electron-binding capability of cluster anions while maintaining their geometrical and electronic structures.Considering the indispensability and convenient availability of the solvents,present findings may boost the potential applications of superatoms in constructing super oxidizers in the condensed phase. | Hao Wang Jun Li Jing Chen Yuxiang Bu Shi-Bo Cheng | 2023 | Chinese Chemical Letters2023，34，11： | 0 |
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