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| 1 | CHIM-geoelectrochemical method in search of concealed mineralisation in China and Australia显示文摘A version of the geoelectrochemical prospecting technique developed in China was demonstrated in China and Australia to test its suitability under both Chinese and Australian conditions.This paper briefly describes the mechanism and effectiveness of the technique applied to search of concealed mineralisation through regolith cover,based on both experimental and field tests.This paer deals with three main aspects of the method: a) how metallic ions are released from orebodies by electrochemical dissolution;b)how these ions migrate to the collector and are deposited as elements by electrochemical extraction in the presence of an electric field; and c) the effectiveness of the method illustrated by some case studies. | LUO Xianrong HOU Baohong WEN Meilanna ZENG Nanshi John Keeling Roger Fidler Adrian Fabris | 2008 | Chinese Journal Of Geochemistry2008，27，2： | 8 |
| 2 | 导致儿童期肥胖的生命早期危险因素:队列研究显示文摘目的确定早年(3岁以内)导致英国儿童肥胖的危险因素。设计前瞻性队列研究。方法Avon英国父母及儿童纵向调查研究。参与者参与队列研究的8234名年龄为7岁的儿童以及亚组的909名重点儿童,后者需额外提供与早期发育有关并涉及可能导致肥胖的各种资料。诊断标准7岁儿童体重指数≥95百分位确定为肥胖,参考1990年英国人口调查的诊断标准。结果经过最终验证,在假设的25项危险因素中有8项与肥胖有关:父母肥胖(父母双方校正后的相对危险度10.44,95%可信区间5.11~21.32);最早期(43个月内)的体重指数或体重反弹升高(校正后的相对危险度15.00,95%可信区间5.32~42.30);3岁时每周看电视的时间超过8小时(校正后的相对危险度1.55,95%可信区间1.13~2.12);追赶性生长(校正后的相对危险度2.60,95%可信区间1.09~6.16);8个月(校正后的相对危险度3.13,95%可信区间1.43~6.85)和18个月(校正后的相对危险度2.65,95%可信区间1.25~5.59)时体重的标准差值;1岁时体重增加值(校正后的相对危险度1.06,95%可信区间1.02~1.10,体重每增加100g);出生体重,每100g(校正后的相对危险度1.05,95%可信区间1.03~1.07);3岁时睡眠不足(<10.5小时,校正后的相对危险度1.45,95%可信区间1.10~1.89)。结论儿童期肥胖可能与8项危险因素有关。 | John J Reilly Julie Amstrong Ahmad R Dorosty Pauline M Emmett A Ness I Rogers Colin Steer Andrea Sherriff Children Study Team 冯凯 | 2005 | 英国医学杂志中文版2005，8，5： | 8 |
| 3 | 随钻声波测井新技术显示文摘在诸多钻井决策中,优选泥浆比重是最具挑战性而且也是最重要的决策之一。如今,新型随钻声波测井仪器的应用能够更好地帮助钻井工程师进行这些钻井决策。 | Jeff Alford Roger B.Goobie Colin M.Sayers Ed Tollefsen Jay Cooke Andy Hawthorn John C.Rasmus Ron Thomas | 2007 | 国外测井技术2007，22，1： | 8 |
| 4 | Utility of tissue microarrays for profiling prognostic biomarkers in clinically localized prostate cancer: the expression of BCL-2, E-cadherin, Ki-67 and p53 as predictors of biochemical failure after radical prostatectomy with nested control for clinical and pathological risk factors显示文摘痊愈不能与经历激进的治疗的临床上局部性的前列腺癌症为所有人被保证。如果他们能改进秘密变形疾病的预言,分子的标记将是无价的。这研究被执行在激进的前列腺切除术标本调查 BCL-2, Ki-67, p53 和 E-cadherin 的表示。我们寻求了估计他们的能力在一个特定的治疗学的背景预言早生物化学的恶化。包括 41 案例对的 82 个病人为病理学的舞台,格利森等级和外科手术前的前列腺特定的抗原(PSA ) 被匹配集中。在每对的一个病人有生物化学的复发(在 2 年外科以内定义为 PSA 0.2 ng mL-1 ) 并且其它没有疾病生物化学地留下了(至少 3 年在外科以后定义同样无法发现的 PSA ) 。Immunohistochemical 分析被执行在四上估计标记表示复制从每个激进的前列腺切除术标本与良性、恶意的织物构造的织物 microarrays。Ki-67, p53 和 BCL-2,然而并非 E-cadherin,显著地在前列腺腺癌的 upregulated 与良性的前列腺织物相比(P < 0.01 ) 。然而,当比较与没有生物化学的复发的病人一起开发了早生物化学的恶化的病人时,在任何标记的表示的重要差别都没被观察。这研究证明 p53, BCL-2 和 Ki-67 的那表情与良性的前列腺织物相比是在临床上局部性的前列腺癌症的 upregulated,没有在 E-cadherin 表示的改变。Biomarker upregulation 没在激进的前列腺切除术以后为生物化学的复发有预示的价值,甚至在考虑病理学的舞台,整个瘤格利森等级和外科手术前的浆液 PSA 水平以后。 | Joseph Nariculam Alex Freeman Simon Bott Phillipa Munson Noriko Cable Nicola Brookman-Amissah Magali Williamson Roger S. Kirby John Masters Mark Feneley | 2009 | Asian Journal of Andrology2009，11，1： | 5 |
| 5 | Heart Disease and Stroke Statistics—2013 Update: A Report From the American Heart Association显示文摘 | Alan S. Go Dariush Mozaffarian Véronique L. Roger Emelia J. Benjamin Jarett D. Berry William B. Borden Dawn M. Bravata Shifan Dai Earl S. Ford Caroline S. Fox Sheila Franco Heather J. Fullerton Cathleen Gillespie Susan M. Hailpern John A. Heit Virginia J. | 2013 | Circulation2013，，1： | 5 |
| 6 | Executive Summary: Heart Disease and Stroke Statistics—2013 Update: A Report From the American Heart Association显示文摘 | Alan S. Go Dariush Mozaffarian Véronique L. Roger Emelia J. Benjamin Jarett D. Berry William B. Borden Dawn M. Bravata Shifan Dai Earl S. Ford Caroline S. Fox Sheila Franco Heather J. Fullerton Cathleen Gillespie Susan M. Hailpern John A. Heit Virginia J. | 2013 | Circulation2013，，1： | 4 |
| 7 | Oil-bearing fluid inclusions from the Palaeoproterozoic:A review of biogeochemical results from time-capsules >2.0 Ga old显示文摘The observation of oil inclusions trapped prior to 2.0 Ga in Palaeoproterozoic rocks and the ability to obtain detailed molecular geochemical information from them provide a robust way for understanding the early biogeochemical evolution of the Earth. Oil-bearing fluid inclusions (FI) in ca. 2.45 Ga fluvial metaconglomerate of the Matinenda Formation at Elliot Lake, Canada were trapped in quartz and feldspar during diagenesis and early metamorphism of the host rock, probably before ca. 2.2 Ga. The 2.1 Ga FA Formation sandstone of the Franceville Basin in Gabon that hosts the Oklo natural fission reactors has also been discovered to contain abundant Palaeoproterozoic oil-bearing FIs. This oil occurs within H2O and CO2-dominated inclusions trapped in syntaxial quartz overgrowths and intragranular and transgranular microfractures in detrital quartz, and was most likely trapped 2.1-1.98 Ga. Molecular geochemical analyses of both FI oils reveal a wide range of compounds, including n-alkanes, isoprenoids, monomethylalkanes, aromatic hydrocarbons, and trace amounts of complex multi-ring biomarkers including terpanes, hopanes, methylhopanes, steranes and diasteranes. To ensure a reliable interpretation of oil inclusions, a comprehensive series of outside-rinse blanks and procedural system blanks was analysed by gas chromatography-mass spectrometry; quantitative amounts of the hydrocarbons in these blanks were compared to the FI extracts, so as to provide confidence limits on the experimental integrity of each compound class. Maturity ratios based on reliably detected compound classes show that the FI oils were generated in the oil window, with no evidence of extensive thermal cracking. The presence of biomarkers for cyanobacteria and eukaryotes derived from and trapped in rocks deposited prior to 2.0 Ga is consistent with early evolution of oxygenic photosynthesis and suggests that some aquatic settings had become sufficiently oxygenated for sterol biosynthesis by this time. The extraction of biomarker molecules from Palaeoproterozoic oil-bearing FIs thus establishes a new method, using low detection limits and system blank levels, to trace evolution through Earth's early history that avoids the potential contamination problems affecting shale-hosted hydrocarbons. | Simon C. GEORGE Adriana DUTKIEWICZ Herbert VOLK John RIDLEY David J. MOSSMAN Roger BUICK | 2009 | Science China Earth Sciences2009，52，1： | 3 |
| 8 | The Systemic Inflammatory Response Syndrome in Acute Liver Failure显示文摘 | Nancy Rolando Jim Wade Milagros Davalos Julia Wendon John Philpott-Howard Roger Williams | 2000 | Hepatology2000，，4： | 3 |
| 9 | The Systemic Inflammatory Response Syndrome in Acute Liver Failure显示文摘 | Nancy Rolando Jim Wade Milagros Davalos Julia Wendon John Philpott-Howard Roger Williams | 2000 | Hepatology2000，，4： | 3 |
| 10 | Expression of Transforming Growth Factor-β1 by Pancreatic Stellate Cells and Its Implications for Matrix Secretion and Turnover in Chronic Pancreatitis显示文摘 | Fanny Wai-Tsing Shek Robert Christopher Benyon Fiona Mairi Walker Peter Raymond McCrudden Sylvia Lin Foon Pender Elizabeth Jean Williams Penelope Ann Johnson Colin David Johnson Adrian Calvin Bateman David Roger Fine John Peter Iredale | 2002 | The American Journal of Pathology2002，，5： | 2 |
| 11 | A multicenter, prospective, randomized comparison of a novel signal transmission capsule endoscope to an existing capsule endoscope显示文摘 | Eric H. Choi Klaus Mergener Carol Semrad Laurel Fisher David R. Cave Milan Dodig Carol Burke Jonathan A. Leighton David Kastenberg Peter Simpson James Sul Kanishka Bhattacharya Roger Charles Lauren Gerson Luke Weber Glenn Eisen Warren Reidel John J. Vargo | 2013 | Gastrointestinal Endoscopy2013，，2： | 2 |
| 12 | Skeletal muscle creatine kinase MB alterations in women marathon runners显示文摘 | Fred S. Apple Marc A. Rogers David C. Casal Linda Lewis John L. Ivy Johanna W. Lampe | 1987 | European Journal of Applied Physiology and Occupational Physiology1987，，1： | 2 |
| 13 | Effect of 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide and N-hydroxysuccinimide concentrations on the mechanical and biological characteristics of cross-linked collagen fibres for tendon repair显示文摘Reconstituted type I collagen fibres have received considerable interest as tendon implant materials due to their chemical and structural similarity to the native tissue.Fibres produced through a semi-continuous extrusion process were cross-linked with different concentrations of the zerolength cross-linker 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide(EDC)in combination with N-hydroxysuccinimide(NHS).Tensile properties of the fibres were considered,along with imaging of both surface structure and fibrillar alignment.Resistance of the fibres to bacterial collagenase was investigated and fibre sections seeded with human tendon cells for biological characterization,including cell adhesion and proliferation.The work clearly demonstrated that whilst the concentration of EDC and NHS had no significant effect on the mechanics,a higher concentration was associated with higher collagenase resistance,but also provided a less attractive surface for cell adhesion and proliferation.A lower cross-linking concentration offered a more biocompatible material without reduction in mechanics and with a potentially more optimal degradability. | Zafar Ahmad Jennifer H.Shepherd David V.Shepherd Siddhartha Ghose Simon J.Kew Ruth E.Cameron Serena M.Best Roger A.Brooks John Wardale Neil Rushton | 2015 | Regenerative Biomaterials2015，2，2： | 2 |
| 14 | Executive Summary: Heart Disease and Stroke Statistics—2012 Update: A Report From the American Heart Association显示文摘 | Véronique L. Roger Alan S. Go Donald M. Lloyd-Jones Emelia J. Benjamin Jarett D. Berry William B. Borden Dawn M. Bravata Shifan Dai Earl S. Ford Caroline S. Fox Heather J. Fullerton Cathleen Gillespie Susan M. Hailpern John A. Heit Virginia J. Howard Bret | 2012 | Circulation2012，，1： | 2 |
| 15 | Cost-Effective Treatment of Patients with Symptomatic Cholelithiasis and Possible Common Bile Duct Stones显示文摘 | Lisa M. Brown Stanley J. Rogers John P. Cello Karen J. Brasel John M. Inadomi | 2011 | Journal of the American College of Surgeons2011，，6： | 2 |
| 16 | Bacterial and Fungal Infection in Acute Liver Failure显示文摘 | Nancy Rolando John Philpott-Howard Roger Williams | 1996 | Semin Liver Dis1996，，04： | 2 |
| 17 | Lessons from look-back in acute liver failure? A single centre experience of 3300 patients显示文摘 | William Bernal Anna Hyyrylainen Amit Gera Vinod K. Audimoolam Mark J.W. McPhail Georg Auzinger Mohammed Rela Nigel Heaton John G. O’Grady Julia Wendon Roger Williams | 2013 | Journal of Hepatology2013，，1： | 2 |
| 18 | LQG Controller Design Applied to a Pneumatic Stewart-Gough Platform显示文摘This paper is concerned with the practical application control of a pneumatically actuated Stewart-Gough platform with 6-degrees of freedom (6-DOF). The control approach for motion control of the platform is presented using a modern control technique, namely, linear quadratic Gaussinn (LQG) with reference tracking. The LQG controller is the combination of a Kalman filter, i.e., a linear-quadratic estimator (LQE) with a linear-quadratic regulator (LQR). The robustness of the control scheme is accessed under various load conditions, and the experimental results are shown. | Karmjit Singh Grewal Roger Dixon John Pearson | 2012 | International Journal of Automation and computing2012，9，1： | 2 |
| 19 | Blockade of PD1 and TIM3 Restores Innate and Adaptive Immunity in Patients with Acute Alcoholic Hepatitis显示文摘 | Lee J.L. Markwick Antonio Riva Jennifer M. Ryan Helen Cooksley Elena Palma Tom H. Tranah Godhev K. Manakkat Vijay Nikhil Vergis Mark Thursz Alex Evans Gavin Wright Sarah Tarff John O’Grady Roger Williams Debbie L. Shawcross Shilpa Chokshi | 2014 | Gastroenterology2014，，： | 2 |
| 20 | MECHANICS ANALYSIS OF TWO-DIMENSIONALLY PRESTRAINED ELASTOMERIC THIN FILM FOR STRETCHABLE ELECTRONICS显示文摘Various methods have been developed to fabricate highly stretchable electronics.Recent studies show that over 100% two dimensional stretchability can be achieved by mesh structure of brittle functioning devices interconnected with serpentine bridges.Kim et al show that pressing down an inflated elastomeric thin film during transfer printing introduces two di-mensional prestrain,and therefore further improves the system stretchability.This paper gives a theoretical study of this process,through both analytical and numerical approaches.Simple analytical solutions are obtained for meridional and circumferential strains in the thin film,as well as the maximum strain in device islands,which all agree reasonably well with finite element analysis. | Ming Li JianUang Xiao Jian Wu Rak-Hwan Kim Zhan Kang Yonggang Huang John A. Rogers | 2010 | Acta Mechanica Solida Sinica2010，23，6： | 2 |
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