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| 1 | Extranodal involvement in young patients with diffuse large B-cell lymphoma: distribution, prognostic value and treatment options显示文摘Objective: Extranodal involvement represents a peculiar presentation of diffuse large B-cell lymphoma(DLBCL). Previous studies have suggested that older patients are more prone to extranodal involvement. This study retrospectively addressed the distribution, prognostic value and treatment options of extranodal involvement in young patients with DLBCL.Methods: A total of 329 patients were enrolled according to the inclusion requirements. The effects of gender,extranodal involvement, age-adjusted international prognostic index(aa IPI), rituximab infusion and radiotherapy on patient outcomes were evaluated.Results: Among these patients, 59% presented extranodal involvement in 16 anatomic sites. More than one instance was linked to many poorer clinical characteristics and poorer survival compared with either nodal disease or one instance. In patients with one extranodal lesion, multivariate analysis revealed that the site of extranodal involvement, but not the aa IPI or rituximab infusion, was independently related to the outcome, and radiotherapy had a negative influence on survival.Conclusions: Extranodal involvement is common in younger patients and exhibits a ubiquitous distribution.The site of extranodal involvement is of strong prognostic significance. Radiotherapy for extranodal lesions does not improve patient outcomes. | Shuna Yao Junbo Li Zhihua Yao Yuanlin Xu Junfeng Chu Jiuyang Zhang Shuiling Jin Yangyang Huang Jianbo Zhang Jie Ma Yan Zhao Shujun Yang Yanyan Liu | 2017 | Chinese Journal of Cancer Research2017,29,1: | 3 |
| 2 | In tegrative iTRAQ-based proteomic and transcriptomic analysis reveals the accumulation patter ns of key metabolites associated with oil quality during seed ripening of Camellia oleifera显示文摘Camellia oleifera(C.oleifera)is one of the four major woody oil-bearing crops in the world and has relatively high ecological,economic,and medicinal value.Its seeds undergo a series of complex physiological and biochemical changes during ripening,which is mainly manifested as the accumulation and transformation of certain metabolites closely related to oil quality,especially flavonoids and fatty acids.To obtain new insights into the underlying molecular mechanisms,a parallel analysis of the transcriptome and proteome profiles of C.oleifera seeds at different maturity levels was conducted using RNA sequencing(RNA-seq)and isobaric tags for relative and absolute quantification(iTRAQ)complemented with gas chromatography-mass spectrometry(GC-MS)data.A total of 16,530 transcripts and 1228 proteins were recognized with significant differential abundances in pairwise comparisons of samples at various developmental stages.Among these,317 were coexpressed with a poor correlation,and most were involved in metabolic processes,including fatty acid metabolism,a-linolenic acid metabolism,and glutathione metabolism.In addition,the content of total flavonoids decreased gradually with seed maturity,and the levels of fatty acids generally peaked at the fat accumulation stage;these results basically agreed with the regulation patterns of genes or proteins in the corresponding pathways.The expression levels of proteins annotated as upstream candidates of phenylalanine ammonia-lyase(PAL)and chalcone synthase(CHS)as well as their cognate transcripts were positively correlated with the variation in the flavonoid content,while shikimate O-hydroxycinnamoyltransferase(HCT)-(encoding genes had the opposite pattern.The increase in the abundance of proteins and mRNAs corresponding to alcohol dehydrogenase(ADH)was associated with a reduction in linoleic acid synthesis.Using weighted gene coexpression network analysis(WGCNA),we further identi fied six unique modules related to flavonoid,oil,and fatty acid anabolism that contained hub genes or proteins similar to transcription factors(TFs),such as MADS intervening keratin-like and C-terminal(MIKC_MAD s),type-B authentic response regulator(ARR-B),and basic helix-loop-helix(bH〔H).Finally,based on the known metabolic pathways and WGCNA combined with the correlation analysis,fi ve coexpressed transcripts and proteins composed of cinnamyl-alcohol dehyd rogenases(CADs),caffeicacid 3-O-methyltransferase(COMT),fl avonol synthase(FLS),and 4-coumarate:CoA ligaas(4CL)were screened out.With this exploratory multiomics dataset,our results presented a dynamic picture regarding the maturation process of C.oleifera seeds on Hainan Island,not only revealing the temporal specific expression of key candidate genes and proteins but also providing a scientific basis for the genetic improvement of this tree species. | Zhouchen Ye Jing Yu Wuping Yan Junfeng Zhang Dongmei Yang Guanglong Yao Zijin Liu Yougen Wu Xilin Hou | 2021 | Horticulture Research2021,8,1: | 3 |
| 3 | Safety and efficacy of meplazumab in healthy volunteers and COVID-19 patients: a randomized phase 1 and an exploratory phase 2 trial显示文摘Recent evidence suggests that CD147 serves as a novel receptor for severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection.Blocking CD147 via anti-CD147 antibody could suppress the in vitro SARS-CoV-2 replication.Meplazumab is a humanized anti-CD147 IgG_(2) monoclonal antibody,which may effectively prevent SARS-CoV-2 infection in coronavirus disease 2019(COVID-19)patients.Here,we conducted a randomized,double-blinded,placebo-controlled phase 1 trial to evaluate the safety,tolerability,and pharmacokinetics of meplazumab in healthy subjects,and an open-labeled,concurrent controlled add-on exploratory phase 2 study to determine the efficacy in COVID-19 patients.In phase 1 study,59 subjects were enrolled and assigned to eight cohorts,and no serious treatment-emergent adverse event(TEAE)or TEAE grade≥3 was observed.The serum and peripheral blood Cmax and area under the curve showed non-linear pharmacokinetic characteristics.No obvious relation between the incidence or titer of positive anti-drug antibody and dosage was observed in each cohort.The biodistribution study indicated that meplazumab reached lung tissue and maintained>14 days stable with the lung tissue/cardiac blood-pool ratio ranging from 0.41 to 0.32.In the exploratory phase 2 study,17 COVID-19 patients were enrolled,and 11 hospitalized patients were involved as concurrent control.The meplazumab treatment significantly improved the discharged(P=0.005)and case severity(P=0.021),and reduced the time to virus negative(P=0.045)in comparison to the control group.These results show a sound safety and tolerance of meplazumab in healthy volunteers and suggest that meplazumab could accelerate the recovery of patients from COVID-19 pneumonia with a favorable safety profile. | Huijie Bian Zhao-Hui Zheng Ding Wei Aidong Wen Zheng Zhang Jian-Qi Lian Wen-Zhen Kang Chun-Qiu Hao Jing Wang Rong-Hua Xie Ke Dong Jie-Lai Xia Jin-Lin Miao Wen Kang Guoquan Li Di Zhang Mingru Zhang Xiu-Xuan Sun Likun Ding Kui Zhang Junfeng Jia Jin Ding Zhiqin Li Yanyan Jia Lin-Na Liu Zhe Zhang Zhao-Wei Gao Hong Du Na Yao Qing Wang Ke Wang Jie-Jie Geng Bin Wang Ting Guo Ruo Chen Yu-Meng Zhu Li-Juan Wang Qian He Rui-Rui Yao Ying Shi Xiang-Min Yang Jian-Sheng Zhou Yi-Nan Ma Ya-Tao Wang Xue Liang Fei Huo Zhe Wang Yang Zhang Xu Yang Ye Zhang Lu-Hua Gao Ling Wang Xiao-Chun Chen Hao Tang Shuang-Shuang Liu Qing-Yi Wang Zhi-Nan Chen Ping Zhu | 2021 | Signal Transduction and Targeted Therapy2021,6,6: | 2 |
| 4 | Timing of uplift and evolution of the Lüliang Mountains,North China Craton显示文摘This study analyses evidence for reformed basin development and basin-mountain coupling associated with development of the Ordos Basin and the Lüliang Mountains, China. Gaining an improved understanding of the timing and nature of uplift and evolution of the Lüliang Mountains is important for the reconstruction of the eastern sedimentary boundary of the Ordos Basin(a major petroliferous basin) as well as for providing insight into the evolution and breakup of the North China Craton(NCC). Based on systematic sampling for fission track analysis, it is suggested that the main phase of uplift of the Lüliang Mountains occurred since later part of the Early Cretaceous. Three evolutionary stages of uplift and development are identified: slow initial uplift(120–65 Ma), accelerated uplift(65–23 Ma), and intensive uplift(23 Ma to present), with the majority of the uplift activity having occurred during the Cenozoic. The history of uplift is non-equilibrium and exhibits complexity in temporal and spatial aspects. The middle and northern parts of the Lüliang Mountains were uplifted earlier than the southern part. The most intensive episode of uplift activity commenced in the Miocene and was associated with a genetic coupling relationship with the eastern neighboring Cenozoic Shanxi Grabens. The uplifting and evolutionary processes of the Lüliang Mountains area since later part of the Early Cretaceous share a unified regional geodynamic setting, which was accompanied by uplift of the Mesozoic Ordos Basin and development of the neighboring Cenozoic Shanxi Grabens. Collectively, this regional orogenic activity is related principally to the far-field effects of both the compression sourced from the southwestern Tibet Plateau and westward subduction of the Pacific Plate in Cenozoic. | ZHAO JunFeng LIU ChiYang Nigel MOUNTNEY LU JianJun CAO JiLong YANG Yao XUE Rui | 2016 | Science China Earth Sciences2016,59,1: | 2 |
| 5 | Changes in the global cryosphere and their impacts:A review and new perspective显示文摘As one of the five components of Earth's climatic system,the cryosphere has been undergoing rapid shrinking due to global warming.Studies on the formation,evolution,distribution and dynamics of cryospheric components and their interactions with the human system are of increasing importance to society.In recent decades,the mass loss of glaciers,including the Greenland and Antarctic ice sheets,has accelerated.The extent of sea ice and snow cover has been shrinking,and permafrost has been degrading.The main sustainable development goals in cryospheric regions have been impacted.The shrinking of the cryosphere results in sea-level rise,which is currently affecting,or is soon expected to affect,17 coastal megacities and some small island countries.In East Asia,South Asia and North America,climate anomalies are closely related to the extent of Arctic sea ice and snow cover in the Northern Hemisphere.Increasing freshwater melting from the ice sheets and sea ice may be one reason for the slowdown in Atlantic meridional overturning circulation in the Arctic and Southern Oceans.The foundations of ports and infrastructure in the circum-Arctic permafrost regions suffer from the consequences of permafrost degradation.In high plateaus and mountainous regions,the cryosphere's shrinking has led to fluctuations in river runoff,caused water shortages and increased flooding risks in certain areas.These changes in cryospheric components have shown significant heterogeneity at different temporal and spatial scales.Our results suggest that the quantitative evaluation of future changes in the cryosphere still needs to be improved by enhancing existing observations and model simulations.Theoretical and methodological innovations are required to strengthen social economies'resilience to the impact of cryospheric change. | ShiYin Liu TongHua Wu Xin Wang XiaoDong Wu XiaoJun Yao Qiao Liu Yong Zhang JunFeng Wei XiaoFan Zhu | 2020 | Research in Cold and Arid Regions2020,12,6: | 2 |
| 6 | An EAV-HP Insertion in 5' Flanking Region of SLCO1B3 Causes Blue Egg- shell in the Chicken显示文摘 | Wang Zhepeng Lujiang Qu Junfeng Yao | 2013 | PLoS Genetics2013,9,10: | 1 |
| 7 | Characteristics of heavy metal accumulation on fly ash-and sewage sludge-amended calcific soil显示文摘Land disposal of fly ash(FA)and sewage sludge(SS)is a major problem due largely to their potentially harmful constituents.In this paper,a potting experiment was performed to evaluate the effects on the plant growth and to discuss in particular the potential hazard to soils and plants according to the characteristics of heavy metal accumulation and migration when FA and SS are used as the amendments of calcific soil in a limestone mining area. The results showed that the application of FA-SS mixture is capable of accelerating the growth of plants and improving the biomass production at either 1:1 or 1:2 FA-SS mixture:soil(w/w).The highest yields were obtained at 1:1(w/w)mixing ratio.When compared with the Element Background Values of Soils in China,the analysis on heavy metals indicated that the contents of Pb,Cr,Hg,Cd,As,Ni,Cu and Zn in the amended soils came up to the second-class environmental quality standards,only Hg and Cd showed significant accumulation.At the same time, though the metal concentrations in roots were higher than those for the control,the concentrations except Cu,Zn in shoots were lower.And all the heavy metal contents in the plants were substantially lower than the toxicity limits. The results indicated that the combined use of FA and SS at a rational rate of application should pose no danger to both soil and food chain based on the characteristics of the FS and SS,heavy metals and calcific soil. | NIU Huapeng LI Shengrong SHEN Junfeng YAO Meijuan | 2012 | Chinese Journal Of Geochemistry2012,31,2: | 1 |
| 8 | Weakened interlayer coupling in two-dimensional MoSe2 flakes with screw dislocations显示文摘The screw dislocations are intriguing defects that are often observed in natural and artificial materials. The dislocation spirals break the reflection and inversion symmetries of the lattices and modify the interlayer coupling in layer-structured materials, inducing additional complexity in layer stacking and thus novel properties in materials. Here, we report on the interlayer coupling of two-dimensional (2D) MoSe2 flakes with screw dislocations by atomic force microscopy (AFM), Raman spectra and photoluminescence (PL) spectra. By controlling the supersaturation conditions, 2D MoSe2 flakes with screw dislocations are grown on amorphous SiO2 substrates by chemical vapor deposition (CVD). AFM measurements reveal that the interlayer spacing in such 2D MoSe2 flakes with screw dislocation is slightly widened with respect to the normal AA- or AB-stacked ones due to the presence of the screw dislocations. Raman and PL spectra show that the interlayer coupling is weaker and thus the band gap is wider than that in the normal AA- or AB-stacked ones. Our work demonstrates that the interlayer coupling of 2D transition metal dichalcogenides (TMDCs) flakes can be tuned by the induction of screw dislocations, which is very helpful for developing novel catalysts and electronic devices. | Xiangzhuo Wang Huixia Yang Rong Yang Qinsheng Wang Jingchuan Zheng Lu Qiao Xianglin Peng Yongkai Li Dongyun Chen Xiaolu Xiong Junxi Duan Guangyu Zhang Jie Ma Junfeng Han Wende Xiao Yugui Yao | 2019 | Nano Research2019,12,8: | 1 |
| 9 | A Topic-Triggered Translation Model for Statistical Machine Translation显示文摘Translation model containing translation rules with probabilities plays a crucial role in statistical machine translation. Conventional method estimates translation probabilities with only the consideration of cooccurrence frequencies of bilingual translation units, while ignoring document-level context information. In this paper, we extend the conventional translation model to a topic-triggered one. Specifically, we estimate topic-specific translation probabilities of translation rules by leveraging topical context information, and online score selected translation rules according to topic posterior distributions of translated sentences. As compared with the conventional model, our model allows for more fine-grained distinction among different translations. Experiment results on large data set demonstrate the effectiveness of our model. | SU Jinsong WANG Zhihao WU Qingqiang YAO Junfeng LONG Fei ZHANG Haiying | 2017 | Chinese Journal of Electronics2017,26,1: | 1 |
| 10 | An EAVHP insertion in 5’flanking region of SLCO1B3causes blue eggshell in the chicken显示文摘 | Zheping Wang Lujiang Qu Junfeng Yao | 2013 | PLOS Genet2013,9,1: | 1 |
| 11 | Paclitaxel liposome for injection (Lipusu) plus cisplatin versus gemcitabine plus cisplatin in the first-line treatment of locally advanced or metastatic lung squamous cell carcinoma: A multicenter, randomized, open-label, parallel controlled clinical study显示文摘Background:Lipusu is the first commercialized liposomal formulation of pacli-taxel and has demonstrated promising efficacy against locally advanced lung squamous cell carcinoma(LSCC)in a small-scale study.Here,we conducted a multicenter,randomized,phase 3 study to compare the efficacy and safety of cis-platin plus Lipusu(LP)versus cisplatin plus gemcitabine(GP)as first-line treat-ment in locally advanced or metastatic LSCC.Methods:Patients enrolled were aged between 18 to 75 years,had locally advanced(clinical stage IIIB,ineligible for concurrent chemoradiation or surgery)or metastatic(Stage IV)LSCC,had no previous systemic chemother-apy and at least one measurable lesion as per the Response Evaluation Criteria in Solid Tumors(version 1.1)before administration of the trial drug.The primary endpoint was progression-free survival(PFS).The secondary endpoints included objective response rate(ORR),disease control rate(DCR),overall survival(OS),and safety profiles.To explore the possible predictive value of plasma cytokines for LP treatment,plasma samples were collected from the LP group at baseline and first efficacy evaluation time and were then subjected to analysis by 45-Plex ProcartaPlex Panel 1 to detect the presence of 45 cytokines using the Luminex xMAP technology.The correlation between treatment outcomes and dynamic changes in the levels of cytokines were evaluated in preliminary analyses.Results:The median duration of follow-up was 15.4 months.237 patients in the LP group and 253 patients in the GP group were included in the per protocol set(PPS).In the PPS,the median PFS was 5.2 months versus 5.5 months in the LP and GP group(hazard rtio[HR]:1.03,P=0.742)respectively.The median OS was 14.6 months versus 12.5 months in the LP and GP group(HR:0.83,P=0.215).The ORR(41.8%versus 45.9%,P=0.412)and DCR(90.3%versus 88.1%,P=0.443)were also similar between the LP and GP group.A significantly lower proportion of patients in the LP group experienced adverse events(AEs)leading to treatment interruptions(10.9%versus 26.4%,P<0.001)or treatment termination(14.3%versus 23.1%,P=0.011).The analysis of cytokine levels in the LP group showed that low baseline levels of 27 cytokines were associated with an increased ORR,and 15 cytokines were associated with improved PFS,with 14 cytokines,including TNF-a,IFN-y,IL-6,and IL-8,demonstrating an overlapping trend.Conclusion:The LP regimen demonstrated similar PFS,OS,ORR and DCR as the GP regimen for patients with locally advanced or metastatic LSCC but had more favorable toxicity profiles.The study also identified a spectrum of different cytokines that could be potentially associated with the clinical benefit in patients who received the LP regimen. | Jie Zhang Yueyin Pan Qin Shi Guojun Zhang Liyan Jiang Xiaorong Dong Kangsheng Gu Huijuan Wang Xiaochun Zhang Nong Yang Yuping Li Jianping Xiong Tienan Yi Min Peng Yong Song Yun Fan Jiuwei Cui Gongyan Chen Wei Tan Aimin Zang Qisen Guo Guangqiang Zhao Ziping Wang Jianxing He Wenxiu Yao Xiaohong Wu Kai Chen Xiaohua Hu Chunhong Hu Lu Yue Da Jiang Guangfa Wang Junfeng Liu Guohua Yu Junling Li Jianling Bai Wenmin Xie Weihong Zhao Lihong Wu Caicun Zhou | 2022 | Cancer Communications2022,42,1: | 1 |
| 12 | A simple method for determining independent fracture toughness and tensile strength of rock显示文摘This paper develops a model that only requires two sets of small-size rock specimens with the ratio of the structural geometry parameter maximum to minimum ae,max:ae,min≥3:1 to determine the rock fracture and strength parameters without size effect and predict the actual structural performance of rock.Regardless of three-point-bending,four-point-bending,or a combination of the above two specimen types,fracture toughness KICand tensile strength ftof rock were determined using only two sets of specimens with ae,max:ae,min≥3:1.The values KICand ftwere consistent with those determined using multiple sets of specimens.The full structural failure curve constructed by two sets of small-size specimens with ae,max:ae,min≥3:1 can accurately predict large-size specimens fracture failure,and±10%upper and lower limits of the curve can encompass the test results of large-size specimens.The peak load prediction curve was constructed by two sets of specimens with ae,max:ae,min≥3:1,and±15%upper and lower limits of the peak load prediction curve can cover the small-size specimen tests data.The model and method proposed in this paper require only two sets of small-size specimens,and their selection is unaffected by the specimen type,geometry,and initial crack length. | Junfeng Guan Yulong Zhang Jiangfeng Meng Xianhua Yao Lielie Li Shuanghua He | 2022 | International Journal of Mining Science and Technology2022,32,4: | 1 |
| 13 | Injectable cartilage matrix hydrogel loaded with cartilage endplate stem cells engineered to release exosomes for non-invasive treatment of intervertebral disc degeneration显示文摘Low back pain,mainly caused by intervertebral disc degeneration(IVDD),is a common health problem;however,current surgical treatments are less than satisfactory.Thus,it is essential to develop novel non-invasive surgical methods for IVDD treatment.Here,we describe a therapeutic strategy to inhibit IVDD by injecting hydrogels modified with the extracellular matrix of costal cartilage(ECM-Gels)that are loaded with cartilage endplate stem cells(CESCs).After loaded with CESCs overexpressing Sphk2(Lenti-Sphk2-CESCs)and injected near the cartilage endplate(CEP)of rats in vivo,ECM-Gels produced Sphk2-engineered exosomes(Lenti-Sphk2-Exos).These exosomes penetrated the annulus fibrosus(AF)and transported Sphk2 into the nucleus pulposus cells(NPCs).Sphk2 activated the phosphatidylinositol 3-kinase(PI3K)/p-AKT pathway as well as the intracellular autophagy of NPCs,ultimately ameliorating IVDD.This study provides a novel and efficient non-invasive combinational strategy for IVDD treatment using injectable ECM-Gels loaded with CESCs that express Sphk2 with sustained release of functional exosomes. | Liwen Luo Junfeng Gong Zhouguang Wang Yao Liu Jiaming Cao Jinghao Qin Rui Zuo Hongyu Zhang Shuai Wang Ping Zhao Di Yang Mengjie Zhang Yanqiu Wang Junfeng Zhang Yue Zhou Changqing Li Bing Ni Zhiqiang Tian MingHan Liu | 2022 | Bioactive Materials2022,7,9: | 1 |
| 14 | Low-temperature synthesis of SrWO4 nano-partieles by a molten salt method显示文摘 | Xiaohui Jiang Junfeng Ma Yan Yao Yong Sun Zhensen Liu Yang Ren Jun Liu Botao Lin | 2009 | Journal of Ceramics International2009,35,8: | 1 |
| 15 | Advanced Process and Electron Device Technology显示文摘This article reviews advanced process and electron device technology of integrated circuits,including recent featuring progress and potential solutions for future development.In 5 years,for pushing the performance of fin field-effect transistors(FinFET)to its limitations,several processes and device boosters are provided.Then,the three-dimensional(3 D)integration schemes with alternative materials and device architectures will pave paths for future technology evolution.Finally,it could be concluded that Moore’s law will undoubtedly continue in the next 15 years. | Dan Zhang Xiaojing Su Hao Chang Hao Xu Xiaolei Wang Xiaobin He Junjie Li Fei Zhao Qide Yao Yanna Luo Xueli Ma Hong Yang Yongliang Li Zhenhua Wu Yajuan Su Tao Yang Yayi Wei Anyan Du Huilong Zhu Junfeng Li Huaxiang Yin Jun Luo Tianchun Ye Wenwu Wang | 2022 | Tsinghua Science and Technology2022,27,3: | 1 |
| 16 | Sprayable nanodrug-loaded hydrogels with enzyme-catalyzed semiinter penetrating polymer network(Semi-IPN)for solar dermatitis显示文摘Solar dermatitis is an acute or chronic high incidence of skin injury caused by ultraviolet(UV)radiation based on strong sunlight,which seriously endangers people's health.In this study,we designed and demonstrated enzyme-catalyzed semi-inter penetrating polymer network(Semi-IPN)sprayable nanodrug-loaded hydrogels based on gelatin,3-(4-hydroxyphenyl)propionic acid(HPA),polyvinyl alcohol(PVA),glycerol,and dexamethasone sodium phosphate(DEXP)for solar dermatitis.The hydrogels had high water content,excellent biocompatibility,effective encapsulation and sustained release of nanodrugs,antiinflammatory,and strong anti-ultraviolet B(anti-UVB)radiation properties based on glycerol and phenol functional groups,but also controllable spray gelation mode to make them adhere well on the dynamic skin surfaces and achieve continuous transdermal drugs delivery for solar dermatitis.The sprayable nanodrug-loaded hydrogel systems could be used as a highly effective therapeutic method for solar dermatitis,and also provide a good strategy for designing novel nanodrug-loaded hydrogel delivery systems. | Jialing Yao Junfeng Hui Jing Yang Jiaxin Yao Chaoquan Hu Daidi Fan | 2022 | Nano Research2022,15,7: | 0 |
| 17 | Selective Hydrogenation of Phenylacetylene by Carbon Monoxide and Water显示文摘Catalytic selective hydrogenation of alkynes to the corresponding alkenes is an important process in industrial production.Modulating the selective hydrogenation of alkynes to the alkenes requires ingenuity since alkenes can easily be converted into the corresponding alkanes under reductive conditions.Applying different reductive reagents to prevent the direct usage of H_(2)can avoid difficulties in hydrogen storage and transportation.Herein,we demonstrate a tandem process to hydrogenate phenylacetylene by CO and H_(2)Oviathecouplingof thelow-temperaturewater-gas shift reaction and selective hydrogenation of phenylacetylene utilizing theα-MoC catalyst.The reductive reagent,CO,not only produces H_(2)from H_(2)O to drive the reaction forward,but it also regulates the selectivity of styrene by preventing further hydrogenation. | Xuetao Qin Ruiqi Zhang Ming Xu Yao Xu Lirong Zheng Chengyu Li Shixiang Yu Jie Yan Jinglin Xie Genghuang Wu Junfeng Rong Meng Wang Ding Ma | 2023 | CCS Chemistry2023,5,10: | 0 |
| 18 | Field-effect at electrical contacts to two-dimensional materials显示文摘The inferior electrical contact to two-dimensional(2D)materials is a critical challenge for their application in post-silicon very large-scale integrated circuits.Electrical contacts were generally related to their resistive effect,quantified as contact resistance.With a systematic investigation,this work demonstrates a capacitive metal-insulator-semiconductor(MIS)field-effect at the electrical contacts to 2D materials:The field-effect depletes or accumulates charge carriers,redistributes the voltage potential,and gives rise to abnormal current saturation and nonlinearity.On one hand,the current saturation hinders the devices’driving ability,which can be eliminated with carefully engineered contact configurations.On the other hand,by introducing the nonlinearity to monolithic analog artificial neural network circuits,the circuits’perception ability can be significantly enhanced,as evidenced using a coronavirus disease 2019(COVID-19)critical illness prediction model.This work provides a comprehension of the field-effect at the electrical contacts to 2D materials,which is fundamental to the design,simulation,and fabrication of electronics based on 2D materials. | Yao Guo Yan Sun Alvin Tang Ching-Hua Wang Yanqing Zhao Mengmeng Bai Shuting Xu Zheqi Xu Tao Tang Sheng Wang Chenguang Qiu Kang Xu Xubiao Peng Junfeng Han Eric Pop Yang Chai | 2021 | Nano Research2021,14,12: | 0 |
| 19 | Outliers rejection in similar image matching显示文摘Background Image matching is crucial in numerous computer vision tasks such as 3D reconstruction and simultaneous visual localization and mapping.The accuracy of the matching significantly impacted subsequent studies.Because of their local similarity,when image pairs contain comparable patterns but feature pairs are positioned differently,incorrect recognition can occur as global motion consistency is disregarded.Methods This study proposes an image-matching filtering algorithm based on global motion consistency.It can be used as a subsequent matching filter for the initial matching results generated by other matching algorithms based on the principle of motion smoothness.A particular matching algorithm can first be used to perform the initial matching;then,the rotation and movement information of the global feature vectors are combined to effectively identify outlier matches.The principle is that if the matching result is accurate,the feature vectors formed by any matched point should have similar rotation angles and moving distances.Thus,global motion direction and global motion distance consistencies were used to reject outliers caused by similar patterns in different locations.Results Four datasets were used to test the effectiveness of the proposed method.Three datasets with similar patterns in different locations were used to test the results for similar images that could easily be incorrectly matched by other algorithms,and one commonly used dataset was used to test the results for the general image-matching problem.The experimental results suggest that the proposed method is more accurate than other state-of-the-art algorithms in identifying mismatches in the initial matching set.Conclusions The proposed outlier rejection matching method can significantly improve the matching accuracy for similar images with locally similar feature pairs in different locations and can provide more accurate matching results for subsequent computer vision tasks. | Qingqing CHEN Junfeng YAO | 2023 | Virtual Reality & Intelligent Hardware2023,5,2: | 0 |
| 20 | East Asian paleoclimate change in the Weihe Basin (central China) since the middle Eocene revealed by clay mineral analysis显示文摘Obtaining a continuous sedimentary record of Cenozoic East Asian paleoclimate change is key to understand the origin,evolution and driving mechanism of the East Asian monsoon and climate change.Based on the continuous Cenozoic fluvial and lacustrine sedimentary sequence in the Weihe Basin,central China,we carried out research on the content and crystal parameters of clay minerals.The paleoclimate change since the middle Eocene was reconstructed accordingly.The results show that smectite and illite are the dominant clay minerals in fluvial-lacustrine sediments of Weihe Basin.The crystallinity of illite,the chemical index of illite,the ratio of smectite to illite and chlorite decrease gradually,which indicates that chemical weathering in the Weihe River watershed stepwise weakened since the middle Eocene,under the background of a semi-arid and semi-humid climate.The formation of palygorskite may be affected by a weak diagenesis.In this case,the content of smectite and the illite crystallinity caused by the weathering in the corresponding period may be actually higher than that of the current,which indicates that the climate in the Weihe Basin region was relatively warm and humid from the middle Eocene to Pliocene.With the decrease of Cenozoic global temperature and the continuous accumulation of sediments,the intensity of chemical weathering in the Weihe Basin gradually weakened,and the East Asian monsoon climate gradually evolved until becoming dry in the Quaternary.Evidence from clay minerals also indicates that the aridification in the Weihe Basin from the late Eocene to the Oligocene may be a response to the global cooling event at the Eocene-Oligocene transition. | Hengzhi LYU Huayu LU Yichao WANG Hanzhi ZHANG Yao WANG Kexin WANG Wen LAI Zhifei LIU Yanli LI Junfeng JI | 2021 | Science China Earth Sciences2021,64,8: | 0 |