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| 1 | Experimental Study on Coal Multi-generation in Dual Fluidized Beds显示文摘为煤多产生的双使流体化的床的一个大气的测试系统被造。一张起泡的使流体化的床为气化并且传播是为燃烧的使流体化的床。二张床与二个阀门被相结合:从燃烧床送高温度灰到气化床的一个阀门和另一个阀门到从气化床把字符和灰送到燃烧床。Shenhua 煤多产生的实验在双使流体化的床上用 1112 K 在温度被做到 1191 K。燃烧室的温度是稳定的,字符燃烧效率是大约 98% 。到使流体化的床的增加的空气 / 煤比率导致温度和气化效率的增加。最大的气化效率是 36.7% ,燃料气体的生热的价值是 10.7 MJ/Nm3。在这个工作的焦油收益是 1.5% ,比热分解的低得多。造成气体和烟道气体的碳变换效率是大约 90% 。 | Fan Xiaoxu Lu Qinggang Na Yongjie Liu Qi | 2007 | Journal of Thermal Science2007，16，3： | 12 |
| 2 | Effect of tip geometry and tip clearance on aerodynamic performance of a linear compressor cascade显示文摘The tip leakage flow between a blade and a casing wall has a strong impact on compressor pressure rise capability, efficiency, and stability. Consequently, there is a strong motivation to look for means to minimize its impact on performance. This paper presents the potential of passive tip leakage flow control to increase the aerodynamic performance of highly loaded compressor blades. Experimental investigations on a linear compressor cascade equipped with blade winglets mounted to the blade tips have been carried out. Results for a variation of the tip clearance and the winglet geometry are presented. Current results indicate that the use of proper tip winglets in a compressor cascade can positively affect the local aerodynamic field by weakening the tip leakage vortex. Results also show that the suction-side winglets are aerodynamically superior to the pressure-side or combined winglets. The suction-side winglets are capable of reducing the exit total pressure loss associated with the tip leakage flow and the passage secondary flow to a significant degree. | Zhong Jingjun Han Shaobing Lu Huawei Kan Xiaoxu | 2013 | Chinese Journal of Aeronautics2013，26，3： | 12 |
| 3 | Transcriptome analysis reveals long noncoding RNAs involved in fiber development in cotton (Gossypium arboreum)显示文摘Long noncoding RNAs(lnc RNAs)play important roles in various biological regulatory processes in yeast,mammals,and plants.However,no systematic identification of lnc RNAs has been reported in Gossypium arboreum.In this study,the strand-specific RNA sequencing(ss RNA-seq)of samples from cotton fibers and leaves was performed,and lnc RNAs involved in fiber initiation and elongation processes were systematically identified and analyzed.We identified 5,996 lnc RNAs,of which 3,510 and 2,486 can be classified as long intergenic noncoding RNAs(linc RNAs)and natural antisense transcripts(lnc NAT),respectively.Linc RNAs and lnc NATs are similar in many aspects,but have some differences in exon number,exon length,and transcript length.Expression analysis revealed that 51.9%of linc RNAs and 54.5%of lnc NATs transcripts were preferentially expressed at one stage of fiber development,and were significantly highly expressed than protein-coding transcripts(21.7%).During the fiber and rapid elongation stages,rapid and dynamic changes in lnc RNAs may contribute to fiber development in cotton.This work describes a set of lnc RNAs that are involved in fiber development.The characterization and expression analysis of lnc RNAs will facilitate future studies on their roles in fiber development in cotton. | Changsong Zou Qiaolian Wang Cairui Lu Wencui Yang Youping Zhang Hailiang Cheng Xiaoxu Feng Mtawa Andrew Prosper Guoli Song | 2016 | Science China(Life Sciences)2016，59，2： | 9 |
| 4 | Anti-β2 glycoprotein I antibodies in complex with β2 glycoprotein I induce platelet activation via two receptors: apolipoprotein E receptor 2' and glycoprotein I ba显示文摘 | Wenjing Zhang Fei Gao Donghe Lu Na Sun Xiaoxue Yin Meili Jin Yanhong Liu | 2016 | Frontiers of Medicine2016，10，1： | 8 |
| 5 | Review of micromachined optical accelerometers:from mg to sub-μg显示文摘Micro-Opto-Electro-Mechanical Systems(MOEMS)accelerometer is a new type of accelerometer which combines the merits of optical measurement and Micro-Electro-Mechanical Systems(MEMS)to enable high precision,small volume and anti-electromagnetic disturbance measurement of acceleration.In recent years,with the in-depth research and development of MOEMS accelerometers,the community is flourishing with the possible applications in seismic monitoring,inertial navigation,aerospace and other industrial and military fields.There have been a variety of schemes of MOEMS accelerometers,whereas the performances differ greatly due to different measurement principles and corresponding application requirements.This paper aims to address the pressing issue of the current lack of systematic review of MOEMS accelerometers.According to the optical measurement principle,we divide the MOEMS accelerometers into three categories:the geometric optics based,the wave optics based,and the new optomechanical accelerometers.Regarding the most widely studied category,the wave optics based accelerometers are further divided into four sub-categories,which is based on grating interferometric cavity,Fiber Bragg Grating(FBG),Fabry-Perot cavity,and photonic crystal,respectively.Following a brief introduction to the measurement principles,the typical performances,advantages and disadvantages as well as the potential application scenarios of all kinds of MOEMS accelerometers are discussed on the basis of typical demonstrations.This paper also presents the status and development tendency of MOEMS accelerometers to meet the ever-increasing demand for high-precision acceleration measurement. | Qianbo Lu Yinan Wang Xiaoxu Wang Yuan Yao Xuewen Wang Wei Huang | 2021 | Opto-Electronic Advances2021，4，3： | 8 |
| 6 | Intracellular and Extracellular Phosphatidylinositol 3-Phosphate Produced by Phytophthora Species Is Important for Infection显示文摘Phytophthora 病原体生产的 RxLR 受动器被建议了把 3 磷酸盐(PtdIns (3 ) P ) 绑在 phosphatidylinositol 调停他们的 translocation 进主人房间或到增加他们在 planta 的稳定性。因为在植物的 PtdIns (3 ) P 的层次是低的,我们检验了 Phytophthora 种类是否可以生产 PtdIns (3 ) 支持感染的 P。我们观察了 P 特定的 GFP 生物传感器能绑在 P 的那 PtdIns (3 ) 。parasitica 和 P。sojae hyphae 短暂地在 Nicotiana benthamiana 的感染期间离开 secreting 生物传感器,建议 hyphae 暴露了 PtdIns (3 ) 他们的血浆膜上的 P 或分泌 PtdIns (3 ) P。phosphatidylinositol 3-kinases (PI3K ) 的 Silencing 基因,有 LY294002 的处理,或 PtdIns (3 ) 的表示由 P 的 P 有约束力的蛋白质。sojae 在大豆上减少了病原体的毒力,显示综合病原体的 PtdIns (3 ) P 为完整的毒力被要求。PtdIns (3 ) 的分泌物 P 有约束力的蛋白质或由 N 的 PI3P-5-kinase。benthamiana 叶子显著地由 P 增加了抵抗的水平到感染。parasitica 和 P。capsici。一起,我们的结果支持假设那 Phytophthora 种生产外部 PtdIns (3 ) 帮助感染的 P,例如支持 RxLR 受动器的入口进宿主细胞。我们的结果源于 P。sojae RxLR 受动器 Avr1b 证实 N 终点和这个受动器的 C 终点能绑 PtdIns (3 ) P。 | Shan Lu | 2013 | Molecular Plant2013，6，5： | 7 |
| 7 | Synthesis of band gap-tunable alkali metal modified graphitic carbon nitride with outstanding photocatalytic H_2O_2 production ability via molten salt method显示文摘Band gap-tunable alkali metal modified graphitic carbon nitride was prepared by a molten salt method.X-ray diffraction, N_2 isothermal sorption, ultraviolet-visible spectroscopy, scanning electron microscope,X-ray photoelectron spectroscopy and photoluminescence were used to characterize the obtained catalysts. The photocatalytic H_2 O_2 production ability of as-prepared catalyst was investigated. The results indicate that K^+ and Na^+ are doped into g-C_3 N_4 lattice simultaneously by the molten salt method. Alkali metal modification not only promotes the specific surface area, visible light absorption and separation of electron-hole pairs, but tunes the conduction band and valence band edge positions of as-prepared catalysts by controlling the weight ratio of eutectic salts to melamine. The tunable band edge positions result in the photocatalytic H_2 O_2 production from 'single channel pathway' to 'two channel pathway',leading to the promoted H_2 O_2 production ability. | Xiaoyu Qu Shaozheng Hu Jin Bai Ping Li Guang Lu Xiaoxue Kang | 2018 | Journal of Materials Science & Technology2018，34，10： | 7 |
| 8 | Mineral photoelectrons and their implications for the origin and early evolution of life on Earth显示文摘Energy is the key issue of all life activities.The energy source and energy yielding pathway are the key scientific issues of the origin and early evolution of life on Earth.Current researches indicate that the utilization of solar energy in large scale by life was an important breaking point of the early evolution of life on Earth and afterwards life gradually developed and flourished.However,in the widespread biochemical electron transfer of life activities,it is still not clear whether the electron source is sun or how electrons originated from sun.For billions of years,the ubiquitous semiconducting minerals in epigeosphere absorb solar energy,forming photoelectrons and photoholes.In reductive and weak acidic environment of early Earth,when photoholes were easily scavenged by reducing matters,photoelectrons were separated.Photoelectrons could effectively reduce carbon dioxide to organic matters,possibly providing organic matter foundation for the origin of life.Photoelectrons participated in photoelectron transfer chains driven by potential difference and transfer into primitive cells to maintain metabolisms.Semiconducting minerals,by absorbing ultraviolet,also protected primitive cells from being damaged by ultraviolet in the origin of life.Due to the continuous photoelectrons generation in semiconducting minerals and utilization by primitive cells,photoelectrons from semiconducting minerals’photocatalysis played multiple roles in the origin of life on early Earth,such as organic synthesis,cell protection,and energy supply.This mechanism still plays important roles in modern Earth surface systems. | LU AnHuai WANG Xin LI Yan DING HongRui WANG ChangQiu ZENG CuiPing HAO RuiXia YANG XiaoXue | 2014 | Science China Earth Sciences2014，57，5： | 5 |
| 9 | Phosphorylation of a wheat aquaporin at two sites enhances both plant growth and defense显示文摘Eukaryotic aquaporins share the characteristic of functional multiplicity in transporting distinct substrates and regulating various processes,but the underlying molecular basis for this is largely unknown.Here,we report that the wheat(Triticum aestivum)aquaporin TaPIP2;10 undergoes phosphorylation to promote photosynthesis and productivity and to confer innate immunity against pathogens and a generalist aphid pest.In response to elevated atmospheric CO_(2)concentrations,TaPIP2;10 is phosphorylated at the serine residue S280 and thereafter transports CO_(2)into wheat cells,resulting in enhanced photosynthesis and increased grain yield.In response to apoplastic H_(2)O_(2) induced by pathogen or insect attacks,TaPIP2;10 is phosphorylated at S121 and this phosphorylated form transports H_(2)O_(2) into the cytoplasm,where H_(2)O_(2)intensifies host defenses,restricting further attacks.Wheat resistance and grain yield could be simultaneously increased by TaPIP2;10 overexpression or by expressing a TaPIP2;10 phosphomimic with aspartic acid substitutions at S121 and S280,thereby improving both crop productivity and immunity. | Kai Lu Xiaochen Chen Xiaohui Yao Yuyan An Xuan Wang Lina Qin Xiaoxu Li Zuodong Wang Shuo Liu Zhimao Sun Liyuan Zhang Lei Chen Baoyan Li Baoyou Liu Weiyang Wang Xinhua Ding Yonghua Yang Meixiang Zhang Shenshen Zou Hansong Dong | 2022 | Molecular Plant2022，15，11： | 2 |
| 10 | The Pumilio RNA-binding protein APUM24 regulates seed maturation by fine-tuning the BPM-WRI1 module in Arabidopsis显示文摘Pumilio RNAbindingproteinsparticipateinmes-senger RNA(mRNA)degradation and t ranslational repression,but their roles in plant development are largely unclear.Here,we show that Arabidopsis PUMILIO PROTEIN24(APUM24),an atypical Pumiliohomology domaincontaining protein,plays an im-portant part in regulating seed maturation,a major stage of plant development.APUM24 is strongly expressed in maturing seeds.Reducing APUM24 expression resulted in abnormal seed maturation,wrinkled seeds,and lower seed oil contents,and APUM24 knockdown resulted in lower levels of WRINKLED 1(WRI1),a key transcription factor con-trolling seed oil accumulation,and lower expression of WRI1 target genes.APUM24 reduces the mRNA stability of BTB/POZMATH(BPM)family genes,thus decreasing BPM protein levels.BPM is responsible for the 26S proteasomemediated degradation of WRI1 and has important functions in plant growth and development.The 3′untranslated regions of BPM family genes contain putative Pumilio response elements(PREs),which are bound by APUM24.Re-duced BPM or increased WRI1 expression rescued the decient seed maturation of apum242 knock-down mutants,and APUM24 overexpression re-sulted in increased seed size and weight.Therefore,APUM24 is crucial to seed maturation through its action as a positive regulatornetuning the BPMWRI1 module,making APUM24 apromising target for breeding strategies to increase crop yields. | Ruihua Huang Mengling Liu Guanping Gong Pingzhi Wu Barunava Patra Ling Yuan Hongting Qin Xiaoxu Wang Guohe Wang Huimei Liao Lu Gao Chengwei Yang Hongqing Li Shengchun Zhang | 2021 | Journal of Integrative Plant Biology2021，63，7： | 2 |
| 11 | The synthesis, bioactivity and paramagnetic resonance of angiotensin Ⅱ and its spin labelled derivative显示文摘ANGIOTENSIN Ⅱ(Ang Ⅱ) is an important constituent in renin-angiotension system (RAS).The amino acid sequence of Ang Ⅱ is DRVYIHPF. Ang Ⅱ plays an important role both inmaintenance of normal blood pressure and in occurrence of hypertension. Ang Ⅱ binding re-ceptor can induce many kinds of physiological effects. Spin labeling is an effective method thatgreatly deepened the knowledge in structure, movement and interaction of biologicalmolecules. For example, it has been used in studying interaction of antigen and antibody suc- | WANG Rui, LI Xiaoxu, HU Xiaoyu, NI Jingman, LI Changling and LU Jingfen1. Department of Biology, State Key Laboratory of Applied Organic Chemistry, Lanzhou 730000, China 2. Department of Chemistry, Lanzhou University, Lanzhou 730000 3. State Key Laboratory of Natural and Biomimetic Drugs, Beijing Medical U-niversity, Beijing 100083, China. | 1997 | Chinese Science Bulletin1997，42，21： | 2 |
| 12 | Design of platinum single-atom doped metal nanoclusters as efficient oxygen reduction electrocatalysts by coupling electronic descriptor显示文摘Inspired by the single-atom catalysts(SACs)concept,we rationally design a series of Pt single atom catalysts embedded in different transition metal nanoclusters through first-principles calculations.In these so-called“crown-jewel”(CJ)structures,Pt atoms(jewels)occupy the vertex sites of the metal nanocluster(crown)surface.We investigated the thermal stability and oxygen reduction reaction(ORR)catalytic activity of these catalysts.The results reveal that CJ-structured PtCu nanoclusters are stable and possess a comparable or even better ORR activity compared to Pt catalyst,making it a promising candidate for low-cost ORR catalysts.The effect of cluster size on the adsorption strength of ORR intermediates and catalytic property has also been studied.Furthermore,the overall ORR catalytic activity trend of these SACs is explained based on analysis of their electronic properties.A descriptorΨwas established to provide further insight into the correlation between the electronic structure and catalytic activity,which provides a design strategy for new ORR catalysts.More importantly,we reveal that this electronic descriptor can be extended to predict other CJ-structured nanoclusters. | Qing Liu Xiaoxu Wang Lu Li Keke Song Ping Qian Yuan Ping Feng | 2022 | Nano Research2022，15，8： | 1 |
| 13 | A note on the equation xy+yz=zx显示文摘 | LU Yulin LI Xiaoxue | 2014 | Journal of Inequalities and Applications2014，2014，： | 1 |
| 14 | Effects of Exposure to Lead and Cadmium on the Oxidative Damage of Livers in Laying Hens显示文摘[Objective] To detect the effects of exposure to lead and cadmium on the oxidative damage of livers in laying hens. [Methods] One hundred and twenty 40-week-old Hyline brown hens were randomly divided into four groups. 100 mg / L Pb and / or 50 mg / L Cd was added into the drinking water for eight weeks. [Results] Compared with control group,AST and ALT activities in Pb group enhanced; but there were no significant differences. AST and ALT activities in Cd group and( Pb + Cd) group significantly or extremely significantly increased( P < 0. 05 or P < 0. 01). SOD activity,GSH- Px activity and GSH content in( Pb + Cd) group,Cd group and Pb group were significantly or extremely significantly lower than those in control group( P <0. 05 or P <0. 01). Among them,( Pb + Cd) group showed the greatest reduction( P <0. 01). MDA contents in the three groups were significantly higher than that of control group; and( Pb +Cd) group was significantly higher than Pb group and Cd group. Cu,Fe and Zn contents in three groups were higher than those in control group in different degrees( P <0. 05 or P <0. 01). Se contents in Cd group and( Pb + Cd) group were significantly lower than that in control group( P <0. 01). Residue contents in livers in Pb group and Cd group were significantly greater than that in control group; while residue content in( Pb + Cd) group was significantly higher than those in Pb group and Cd group. Ultrastructure showed that there were symptoms of mitochondrial swelling and fractured cristae in liver cells of laying hens after the exposure to Cd and Pb. In( Pb + Cd) group,these symptoms were even greater. [Conclusion] Oxidative damage and disturbance of trace element metabolism were one of the mechanisms for hepatotocity in laying hens induced by Pb and Cd,and synergistic effect lied in the coadministration. | Chen Dawei Pu Junhua Tang Xiujun Lu Junxian Liu Yinyin Jia Xiaoxu Ge Qinglian Gao Yushi | 2014 | Animal Husbandry and Feed Science2014，6，5： | 1 |
| 15 | A note on vertex-arboricity of plane graphs 显示文摘 | Lu Xiaoxu Xu Baogang | 2007 | Journal of Nanjing University: Natural Sciences2007，43，1： | 1 |
| 16 | Transcriptome-wide Dynamics of m^(6)A mRNA Methylation During Porcine Spermatogenesis显示文摘Spermatogenesis is a continual process that occurs in the testes,in which diploid spermatogonial stem cells(SSCs)differentiate and generate haploid spermatozoa.This highly efficient and intricate process is orchestrated at multiple levels.N^(6)-methyladenosine(m^(6)A),an epigenetic modification prevalent in mRNAs,is implicated in the transcriptional regulation during spermatogenesis.However,the dynamics of m^(6)A modification in non-rodent mammalian species remains unclear.Here,we systematically investigated the profile and role of m^(6)A during spermatogenesis in pigs.By analyzing the transcriptomic distribution of m^(6)A in spermatogonia,spermatocytes,and round spermatids,we identified a globally conserved m^(6)A pattern between porcine and murine genes with spermatogenic function.We found that m^(6)A was enriched in a group of genes that specifically encode the metabolic enzymes and regulators.In addition,transcriptomes in porcine male germ cells could be subjected to the m^(6)A modification.Our data show that m^(6)A plays the regulatory roles during spermatogenesis in pigs,which is similar to that in mice.Illustrations of this point are three genes(SETDB1,FOXO1,and FOXO3)that are crucial to the determination of the fate of SSCs.To the best of our knowledge,this study for the first time uncovers the expression profile and role of m^(6)A during spermatogenesis in large animals and provides insights into the intricate transcriptional regulation underlying the lifelong male fertility in non-rodent mammalian species. | Zidong Liu Xiaoxu Chen Pengfei Zhang Fuyuan Li Lingkai Zhang Xueliang Li Tao Huang Yi Zheng Taiyong Yu Tao Zhang Wenxian Zeng Hongzhao Lu Yinghua Lv | 2023 | Genomics, Proteomics & Bioinformatics2023，21，4： | 1 |
| 17 | Fabrication of Flexible Thermoelectric Thin Film Devices by Inkjet Printing 显示文摘 | Lu Ziyang Layani Michael Zhao Xiaoxu | 2014 | Small2014，10，17： | 1 |
| 18 | Contamination assessment and health risk of heavy metals in dust from Changqing industrial park of Baoji, NW China显示文摘 | Lijun Wang Xinwei Lu Chunhui Ren Xiaoxue Li Cancan Chen | 2014 | Environmental Earth Sciences2014，，5： | 1 |
| 19 | A non-ACE2 competing human single-domain antibody confers broad neutralization against SARS-CoV-2 and circulating variants显示文摘The current COVID-19 pandemic has heavily burdened the global public health system and may keep simmering for years.The frequent emergence of immune escape variants have spurred the search for prophylactic vaccines and therapeutic antibodies that confer broad protection against SARS-CoV-2 variants.Here we show that the bivalency of an affinity maturated fully human singledomain antibody(n3113.1-Fc)exhibits exquisite neutralizing potency against SARS-CoV-2 pseudovirus,and confers effective prophylactic and therapeutic protection against authentic SARS-CoV-2 in the host cell receptor angiotensin-converting enzyme 2(ACE2)humanized mice.The crystal structure of n3113 in complex with the receptor-binding domain(RBD)of SARS-CoV-2,combined with the cryo-EM structures of n3113 and spike ecto-domain,reveals that n3113 binds to the side surface of up-state RBD with no competition with ACE2.The binding of n3113 to this novel epitope stabilizes spike in up-state conformations but inhibits SARS-CoV-2 S mediated membrane fusion,expanding our recognition of neutralization by antibodies against SARS-CoV-2.Binding assay and pseudovirus neutralization assay show no evasion of recently prevalent SARS-CoV-2 lineages,including Alpha(B.1.1.7),Beta(B.1.351),Gamma(P.1),and Delta(B.1.617.2)for n3113.1-Fc with Y58L mutation,demonstrating the potential of n3113.1-Fc(Y58L)as a promising candidate for clinical development to treat COVID-19. | Zhenlin Yang Yulu Wang Yujia Jin Yuanfei Zhu Yanling Wu Cheng Li Yu Kong Wenping Song Xiaolong Tian Wuqiang Zhan Ailing Huang Shanshan Zhou Shuai Xia Xiaoxu Tian Chao Peng Cuicui Chen Yibing Shi Gaowei Hu Shujuan Du Yuyan Wang Youhua Xie Shibo Jiang Lu Lu Lei Sun Yuanlin Song Tianlei Ying | 2021 | Signal Transduction and Targeted Therapy2021，6，12： | 1 |
| 20 | African swine fever virus MGF505-3R inhibits cGAS-STING-mediated IFN-βpathway activation by degrading TBK1显示文摘African swine fever virus(ASFV)is an important pathogen causing acute infectious disease in domestic pigs and wild boars that seriously endangers the global swine industry.As ASFV is structurally complex and encodes a large number of functional proteins,no effective vaccine has been developed to date.Thus,dissecting the mechanisms of immune escape induced by ASFV proteins is crucial.A previous study showed that the ASFV-encoded protein is an important factor in host immunity.In this study,we identified a negative regulator,MGF505-3R,that significantly downregulated cGAS/STING-and poly(dG:dC)-mediated IFN-βand interferon stimulation response element(ISRE)reporter activity and suppressed IFNB1 and IFIT2 mRNA levels.In addition,TBK1,IRF3 and IκBαphosphorylation levels were also inhibited.Mechanistically,MGF505-3R interacted with cGAS/TBK1/IRF3 and targeted TBK1 for degradation,thereby disrupting the cGAS-STING-mediated IFN-βsignaling pathway,which appears to be highly correlated with autophagy.Knockdown MGF505-3R expression enhanced IFN-βand IL-1βproduction.Taken together,our study revealed a negative regulatory mechanism involving the MGF505-3R-cGAS-STING axis and provided insights into an evasion strategy employed by ASFV that involves autophagy and innate signaling pathways. | Mingyang Cheng Jiawei Luo Yuetong Duan Yu Yang Chunwei Shi Yu Sun Yiyuan Lu Junhong Wang Xiaoxu Li Jianzhong Wang Nan Wang Wentao Yang Yanlong Jiang Guilian Yang Yan Zeng Chunfeng Wang Xin Cao | 2022 | Animal Diseases2022，2，3： | 1 |
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