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| 1 | Advances in diagnosis, treatment and palliation of pancreatic carcinoma: 1990-2010显示文摘Several advances in genetics, diagnosis and palliation of pancreatic cancer (PC) have occurred in the last decades. A multidisciplinary approach to this disease is therefore recommended. PC is relatively common as it is the fourth leading cause of cancer related mortality. Most patients present with obstructive jaundice, epigastric or back pain, weight loss and anorexia. Despite improvements in diagnostic modalities, the majority of cases are still detected in advanced stages. The only curative treatment for PC remains surgical resection. No more than 20% of patients are candidates for surgery at the time of diagnosis and survival remains quite poor as adjuvant therapies are not very effective. A small percentage of patients with borderline non-resectable PC might benefit from neo-adjuvant chemoradiation therapy enabling them to undergo resection; however, randomized controlled studies are needed to prove the benefits of this strategy. Patients with unresectable PC benefit from palliative interventions such as biliary decompression and celiac plexus block. Further clinical trials to evaluate new chemo and radiation protocols as well as identification of genetic markers for PC are needed to improve the overall survival of patients affected by PC, as the current overall 5-year survival rate of patients affected by PC is still less than 5%. The aim of this article is to review the most recent high quality literature on this topic. | Chakshu Sharma Karim M Eltawil Paul D Renfrew Mark J Walsh Michele Molinari | 2011 | World Journal of Gastroenterology2011，17，7： | 28 |
| 2 | Effects of raloxifene on serum lipids and coagulation factors in healthy postmenopausal women显示文摘 | Kuller LH Paul S | 1998 | JAMA1998，279，18： | 1 |
| 3 | The ATHEROMA (Atorvastatin Therapy: Effects on Reduction of Macrophage Activity) Study显示文摘 | Tjun Y. Tang Simon P.S. Howarth Sam R. Miller Martin J. Graves Andrew J. Patterson Jean-Marie U-King-Im Zhi Y. Li Stewart R. Walsh Andrew P. Brown Peter J. Kirkpatrick Elizabeth A. Warburton Paul D. Hayes Kevin Varty Jonathan R. Boyle Michael E. Gaunt And | 2009 | Journal of the American College of Cardiology2009，，22： | 1 |
| 4 | Biological markers of amyloid β-related mechanisms in Alzheimer’s disease显示文摘 | Harald Hampel Yong Shen Dominic M. Walsh Paul Aisen Les M. Shaw Henrik Zetterberg John Q. Trojanowski Kaj Blennow | 2009 | Experimental Neurology2009，，2： | 1 |
| 5 | The effects of hormone replacement therapy and raloxifene on C-reactive protein and homocysteine in healthy postmenopausal women: a randomized, controlled trial显示文摘 | Walsh B W Paul S Wild R A | 2000 | J Endocrinol Metabol2000，85，： | 1 |
| 6 | Long-Term Survival, Modes of Death, and Predictors of Mortality in Patients With Fontan Surgery显示文摘 | Paul Khairy Susan M. Fernandes John E. Mayer John K. Triedman Edward P. Walsh James E. Lock Michael J. Landzberg | 2008 | Circulation2008，，1： | 1 |
| 7 | 显示文摘 | Walsh BW Paul S Wild RA | 2000 | J Clin Endocrinol Metab2000，85，： | 1 |
| 8 | Postoperative Course and Hemodynamic Profile After the Arterial Switch Operation in Neonates and Infants. A Comparison of Low-Flow Cardiopulmonary Bypass and Circulatory Arrest显示文摘 | Gil Wernovsky David Wypij Richard A. Jonas John E. Mayer Frank L. Hanley Paul R. Hickey Amy Z. Walsh Anthony C. Chang Aldo R. Castaneda Jane W. Newburger David L. Wessel | 1995 | Circulation1995，，8： | 1 |
| 9 | Role of angiography and embolization for massive gastroduodenal hemorrhage显示文摘 | R. Matthew Walsh M.D. Paul Anain M.D. Michael Geisinger M.D. David Vogt M.D. James Mayes M.D. Sharon Grundfest-Broniatowski M.D. J. Michael Henderson M.D | 1999 | Journal of Gastrointestinal Surgery1999，，1： | 1 |
| 10 | Isolation and Analysis of Bacteria with Antimicrobial Activities from the Marine Sponge Haliclona simulans Collected from Irish Waters显示文摘 | Jonathan Kennedy Paul Baker Clare Piper Paul D. Cotter Marcella Walsh Marlies J. Mooij Marie B. Bourke Mary C. Rea Paula M. O’Connor R. Paul Ross Colin Hill Fergal O’Gara Julian R. Marchesi Alan D. W. Dobson | 2009 | Marine Biotechnology2009，，3： | 1 |
| 11 | Geochemistry of hydrothermal fluids from the PACMANUS, Northeast Pual and Vienna Woods hydrothermal fields, Manus Basin, Papua New Guinea显示文摘 | Eoghan P. Reeves Jeffrey S. Seewald Peter Saccocia Wolfgang Bach Paul R. Craddock Wayne C. Shanks Sean P. Sylva Emily Walsh Thomas Pichler Martin Rosner | 2010 | Geochimica et Cosmochimica Acta2010，，4： | 1 |
| 12 | Stokes polarimetry imaging of rat tail tissue in a turbid medium: degree of linear polarization image maps using incident linearly polarized light显示文摘 | Paul J Wu Joseph T Walsh | 2006 | J Biomed Opt2006，11，01： | 1 |
| 13 | Effects of Low-Intensity Pulsed Ultrasound on Tendon–Bone Healing in an Intra-articular Sheep Knee Model显示文摘 | William R. Walsh Paul Stephens Frank Vizesi Warwick Bruce James Huckle Yan Yu | 2007 | Arthroscopy: The Journal of Arthroscopic and Related Surgery2007，，2： | 1 |
| 14 | PICAXE Infrared Remote Switch for Decora- tive LED Light 显示文摘 | Paul Walsh | 2011 | Silicon Chip2011，24，9： | 1 |
| 15 | Impact of Induction Chemotherapy and Preoperative Chemoradiotherapy on Operative Morbidity and Mortality in Patients with Locoregional Adenocarcinoma of the Stomach or Gastroesophageal Junction显示文摘 | Kazumasa Fujitani Jaffer A. Ajani Christopher H. Crane Barry W. Feig Peter W. Pisters Nora Janjan Garrett L. Walsh Stephen G. Swisher Ara A. Vaporciyan David Rice Angela Welch Jackie Baker Josephine Faust Paul F. Mansfield | 2007 | Annals of Surgical Oncology2007，，7： | 1 |
| 16 | Effect of Anesthesia Type on Limb Length Discrepancy After Total Hip Arthroplasty显示文摘 | Sathappan S. Sathappan Daniel Ginat Vipul Patel Michael Walsh William L. Jaffe Paul E. Di Cesare | 2008 | The Journal of Arthroplasty2008，，2： | 1 |
| 17 | Determinants of short- and long-term survival from colorectal cancer in very elderly patients显示文摘 | Juliette Sheridan Paul Walsh David Kevans Therese Cooney Shane O’Hanlon Blathnaid Nolan Anne White Edel McDermott Kieran Sheahan Diarmuid O’Shea John Hyland Diarmuid O’Donoghue Jacintha O’Sullivan Hugh Mulcahy Glen Doherty | 2014 | Journal of Geriatric Oncology2014，，： | 1 |
| 18 | Impact of Induction Chemotherapy and Preoperative Chemoradiotherapy on Operative Morbidity and Mortality in Patients with Locoregional Adenocarcinoma of the Stomach or Gastroesophageal Junction显示文摘 | Kazumasa Fujitani Jaffer A. Ajani Christopher H. Crane Barry W. Feig Peter W. Pisters Nora Janjan Garrett L. Walsh Stephen G. Swisher Ara A. Vaporciyan David Rice Angela Welch Jackie Baker Josephine Faust Paul F. Mansfield | 2007 | Annals of Surgical Oncology2007，，7： | 1 |
| 19 | PICAXE infrared remote switch for decorative LED light显示文摘 | Paul Walsh | 2011 | Silicon Chip2011，24，9： | 1 |
| 20 | The relative abuse liability of oral oxycodone, hydrocodone and hydromorphone assessed in prescription opioid abusers显示文摘 | Sharon L. Walsh Paul A. Nuzzo Michelle R. Lofwall Joseph R. Holtman | 2008 | Drug and Alcohol Dependence2008，，： | 1 |
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