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| 1 | Climatic and lake environmental changes in the Serling Co region of Tibet over a variety of timescales显示文摘The Serling Co region is located at the transitional zone of the interaction between the Indian monsoon and the westerlies over the Tibetan Plateau. The Serling Co lake covers a water area of2,389 km2(June 2017) in a 45,530 km2drainage basin. Under the dramatic hydro-meteorological changes on the Tibetan Plateau in recent decades, and complex hydrological compositions of rivers and lakes in the basin, the lake area expanded by 43%, from1,667 km2in 1976, to 2,389 km2in 2017 (1)In 2014 it surpassed Nam Co as the largest lake on the Tibetan Plateau [2], and exerts significant effect on regional environmental conditions. | Liping Zhu Junbo Wang Jianting Ju Ning Ma Yinsheng Zhang Chong Liu Boping Han Linshan Liu Mingda Wang Qingfeng Ma | 2019 | Science Bulletin2019，64，7： | 13 |
| 2 | A group of SUVH methyl-DNA binding proteins regulate expression of the DNA demethylase ROS_1 in Arabidopsis显示文摘DNA methylation is typically regarded as a repressive epigenetic marker for gene expression.Genome-wide DNA methylation patterns in plants are dynamically regulated by the opposing activities of DNA methylation and demethylation reactions. In Arabidopsis, a DNA methylation monitoring sequence(MEMS) in the promoter of the DNA demethylase gene ROS_1 functions as a methylstat that senses these opposing activities and regulates genome DNA methylation levels by adjusting ROS_1 expression. How DNA methylation in the MEMS region promotes ROS_1 expression is not known. Here, we show that several Su(var)3-9 homologs(SUVHs) can sense DNA methylation levels at the MEMS region and function redundantly to promote ROS_1 expression. The SUVHs bind to the MEMS region, and the extent of binding is correlated with the methylation level of the MEMS.Mutations in the SUVHs lead to decreased ROS_1 expression, causing DNA hypermethylation at more than 1,000 genomic regions. Thus, the SUVHs function to mediate the activation of gene transcription by DNA methylation. | Xinlong Xiao Jieqiong Zhang Tao Li Xing Fu Viswanathan Satheesh Qingfeng Niu Zhaobo Lang Jian-Kang Zhu Mingguang Lei | 2019 | Journal of Integrative Plant Biology2019，61，2： | 11 |
| 3 | Catalytic Reduction of CO2 to CO via Reverse Water Gas Shift Reaction:Recent Advances in the Design of Active and Selective Supported Metal Catalysts显示文摘The catalytic conversion of CO2 to CO via a reverse water gas shift(RWGS)reaction followed by well-established synthesis gas conversion technologies may provide a potential approach to convert CO2 to valuable chemicals and fuels.However,this reaction is mildly endothermic and competed by a strongly exothermic CO2 methanation reaction at low temperatures.Therefore,the improvement in the low-temperature activities and selectivity of the RWGS reaction is a key challenge for catalyst designs.We reviewed recent advances in the design strategies of supported metal catalysts for enhancing the activity of CO2 conversion and its selectivity to CO.These strategies include varying support,tuning metal–support interactions,adding reducible transition metal oxide promoters,forming bimetallic alloys,adding alkali metals,and enveloping metal particles.These advances suggest that enhancing CO2 adsorption and facilitating CO desorption are key factors to enhance CO2 conversion and CO selectivity.This short review may provide insights into future RWGS catalyst designs and optimization. | Min Zhu Qingfeng Ge Xinli Zhu | 2020 | Transactions of Tianjin University2020，26，3： | 9 |
| 4 | Pollen-inferred Holocene vegetation and climate histories in Taro Co,southwestern Tibetan Plateau显示文摘A 310-cm-long sediment core,covering the last10,200 years,was collected from Taro Co on the southwestern Tibetan Plateau and analyzed for pollen,grain size and total inorganic carbon content.The pollen data showed that vegetation changed from alpine steppe to alpine meadow during 10,200–8,900 cal a BP,to alpine steppe dominated by Artemisia during 8,900–7,400 cal a BP,to alpine meadow during 7,400–3,300 cal a BP and to alpine steppe after 3,300 cal a BP.Correspondingly,the pollen,grain size and total inorganic carbon content results revealed climatic change in this area over four stages.The initial stage was from 10,200 to 8,900 cal a BP,during which the climate changed from cold-dry to warm-humid.The second stage(8,900–7,400 cal a BP)was characterized by a warm and dry climate.However,at approximately7,400 cal a BP,the climate began to become cold and humid,which continued until 3,300 cal a BP.The last stage,from 3,300 cal a BP to present,was characterized as cold and increasingly arid.Climatic events of the early and mid-late Holocene showed that the area was significantly affected by the westerlies.However,the mid-Holocene climate in Taro Co was controlled by the Indian monsoon.The mid-late Holocene depositional environment record of Taro Co was very important to further elaborate the degree of influence by the westerlies or Indian monsoon. | Qingfeng Ma Liping Zhu Xinmiao L Yun Guo Jianting Ju Junbo Wang Yong Wang Lingyu Tang | 2014 | Chinese Science Bulletin2014，59，31： | 7 |
| 5 | Forward-backward doubly stochastic differential equations and related stochastic partial differential equations显示文摘The notion of bridge is introduced for systems of coupled forward-backward doubly stochastic differential equations (FBDSDEs). It is proved that if two FBDSDEs are linked by a bridge, then they have the same unique solvability. Consequently, by constructing appropriate bridges, we obtain several classes of uniquely solvable FBDSDEs. Finally, the probabilistic interpretation for the solutions to a class of quasilinear stochastic partial differential equations (SPDEs) combined with algebra equations is given. One distinctive character of this result is that the forward component of the FBDSDEs is coupled with the backward variable. | ZHU QingFeng SHI YuFeng | 2012 | Science China Mathematics2012，55，12： | 6 |
| 6 | The next generation models for crops and agro-ecosystems显示文摘Growth in population, decrease in arable land area, and change in climate are endangering our food security. Precision agriculture has the potential to increase crop productivity thorough tailored agricultural practices for different growing areas. Many models of crops and agro-ecosystems capable of predicting interaction between plants and environments have been developed for precision agriculture. Currently, there are several representative categories of crop and agro-ecosystem models, including the de Wit school models, the DSSAT series models and the APSIM series models, which have contributed substantially to improvement of agricultural practices. However, these models are weak in predicting performances of crops under environmental and genetic perturbations are generally weak, which severely limits the application of these models in guiding precision agriculture. We need to develop the next generation crop and agro-ecosystems models with a high level of mechanistic basis, which can be integrated with high throughput data and can predict the heterogeneity of environmental factors inside canopy and dynamic canopy photosynthesis. In developing such a model close collaboration is inevitably required among scientists from different disciplines. The successful development and application of such models will undoubtedly advance precision agriculture through providing better agronomical practices tailored for different growing environments. These models will also form a basis to identify breeding targets for increased productivity at given location with given soil and climatic conditions. | ZHU XinGuang ZHANG GuiLian THOLEN Danny WANG Yu XIN ChangPeng SONG QingFeng | 2011 | Science China(Information Sciences)2011，54，3： | 6 |
| 7 | Backward Doubly Stochastic Differential Equations with Jumps and Stochastic Partial Differential-Integral Equations显示文摘Backward doubly stochastic differential equations driven by Brownian motions and Poisson process(BDSDEP) with non-Lipschitz coeffcients on random time interval are studied.The probabilistic interpretation for the solutions to a class of quasilinear stochastic partial differential-integral equations(SPDIEs) is treated with BDSDEP.Under non-Lipschitz conditions,the existence and uniqueness results for measurable solutions to BDSDEP are established via the smoothing technique.Then,the continuous dependence for solutions to BDSDEP is derived.Finally,the probabilistic interpretation for the solutions to a class of quasilinear SPDIEs is given. | Qingfeng ZHU Yufeng SHI | 2012 | Chinese Annals of Mathematics,Series B2012，33，1： | 5 |
| 8 | Syndecan-2, negatively regulated by miR-20b-5p, contributes to 5-fluorouracil resistance of colorectal cancer cells via the JNK/ERK signaling pathway显示文摘5-Fluorouracil (5-FU) resistance has been long considered as an obstacle to the efficacy of chemotherapy in colorectal cancer (CRC). In this study, we demonstrated the role of miR-20b-5p-regulated syndecan-2 (SDC2) in 5-FU resistance of CRC cells. 5-FU-resistant SW480 CRC cells were established by treatment of SW480 cells with stepwise increase of 5-FU concentration. The results showed that SDC2 was expressed significantly higher in SW480/5-FU cells than in SW480/WT cells as revealed by quantitative real-time polymerase chain reaction and western blot analysis. MTT assay and BrdU assay showed that SDC2 overexpression led to increased cell survival rate, while SDC2 knockdown reversed the drug resistance of SW480/5-FU cells. Wound healing and transwell invasion assays revealed that knockdown of SDC2 inhibited the migratory and invasive ability of SW480/5-FU cells. Moreover, animal experiments indicated that si-SDC2 plays a suppressive role in tumor growth in vivo. We also confirmed that miR-20b-5p interacted with SDC2, which reversed the effect of SDC2 in SW480/5-FU cells via the c-Jun N-terminal kinase (JNK)/extracellular regulated protein kinases (ERK) signaling pathway. These findings showed that JNK/ERK signaling pathway is involved in miR-20b-5p/SDC2 axis-mediated 5-FU resistance in SW480/5-FU cells, indicating that the miR-20b-5p/SDC2 axis is a potential target for reversing 5-FU resistance in CRC. | Ruheng Hua Yan Zhang Xiyue Yan Dong Tang Xiaolong Li Qingfeng Ni Daorong Wang Jianwei Zhu | 2021 | Acta Biochimica et Biophysica Sinica2021，53，11： | 4 |
| 9 | Systems model-guided rice yield improvements based on genes controlling source, sink, and flow显示文摘A large number of genes related to source, sink,and flow have been identified after decades of research in plant genetics. Unfortunately, these genes have not been effectively utilized in modern crop breeding. This perspective paper aims to examine the reasons behind such a phenomenon and propose a strategy to resolve this situation. Specifically, we first systematically survey the currently cloned genes related to source, sink, and flow;then we discuss three factors hindering effective application of these identified genes, which include the lack of effective methods to identify limiting or critical steps in a signaling network, the misplacement of emphasis on properties, at the leaf, instead of the whole canopy level,and the non-linear complex interaction between source,sink, and flow. Finally, we propose the development of systems models of source, sink and flow, together with a detailed simulation of interactions between them and their surrounding environments, to guide effective use of the identified elements in modern rice breeding. These systems models will contribute directly to the definition of crop ideotype and also identification of critical features and parameters that limit the yield potential in current cultivars. | Pan Li Tiangen Chang Shuoqi Chang Xiang Ouyang Mingnan Qu Qingfeng Song Langtao Xiao Shitou Xia Qiyun Deng Xin-Guang Zhu | 2018 | Journal of Integrative Plant Biology2018，60，12： | 4 |
| 10 | Climatic significance of n-alkanes and their compound-specific dD values from lake surface sediments on the Southwestern Tibetan Plateau显示文摘The content and hydrogen isotope ratios of n-alkanes extracted from recent lake surface sediments sampled from nine lakes in three different climate zones on the Southwestern Tibetan Plateau were analyzed.Values were compared with n-alkanes in plants from lake drainages,and dD values of meteoric water,lake water,and mean annual precipitation.The results showed that n-C23was predominantly derived from aquatic plants,and n-C27–n-C33from terrestrial higher plants.The average carbon chain length of n-C27–n-C33(ACL27–33)was positively correlated with the mean annual precipitation.dD values of the long-chain n-alkanes n-C29and n-C31of terrestrial origin(varying between-214%and-169%,and-226%and-185%,respectively)were inversely correlated with mean annual precipitation;but in accordance with the average annual variations in dD(OIPC),dD values of n-C31were strongly related to the dD values of growing season meteoric water(R2=0.74).The large difference between dD values of n-C23of aquatic origin and n-C31(an average of about 27%)demonstrates the enrichment of the lake water dD compared to precipitation,caused by strong evaporation in the semiarid–arid areas of the southwestern Tibetan Plateau.Average value of en C25 31=p(-95%)is evidently higher than the value observed in European wet regions(-128%);besides,en C31(about-116%)is constant along the study transect(SD=9),which indicates that n-C31is a useful proxy for the environment. | Xing Hu Liping Zhu Yong Wang Junbo Wang Ping Peng Qingfeng Ma Jianfang Hu Xiao Lin | 2014 | Chinese Science Bulletin2014，59，24： | 3 |
| 11 | ePlant for quantitative and predictive plant science research in the big data era --Lay the foundation for the future model guided crop breeding, engineering and agronomy显示文摘背景在着急地在最近的十年统一陆地区域基础上的庄稼产量的全球人口,气候变化和停滞的增加打电话让一条新途径支持当代的庄稼改进。ePlant 与机械学的细节的高水平是植物生长和开发的一个数学模型遇见这挑战。结果 ePlant 集成为过程发生在开发的模块急速地不同时间( 108106 秒)并且空间( 101010 米)可伸缩,合并多样的物理、生物物理、生物化学的过程包括基因规定,新陈代谢的反应,底层运输和散开,精力吸收,转移和变换,机关形态发生,植物环境相互作用,等等。单个模块用一条 divide-and-conquer 途径被开发;在不同时间、空间的规模的模块进一步通过转移 variables.We 是综合的基于信息几何学建议一个监督学习过程为两知识发现和模型扩展或进展联合模型和数据。我们最后讨论一个全球协会的最近的形成,它在植物生物学包括专家,计算机科学,统计,农学, phenomics ,等等试图由支持模型作为一个社区努力被开发而不是在哪儿的一个新模型开发范例帮助 ePlant 或它的等价物的开发和应用程序主要由单个实验室努力开车。结论 ePlant 支持量、预兆的植物科学研究的一个主要研究工具,将在未来模型起一个关键作用指导庄稼工程,繁殖并且农学。 | Yi Xiao Tiangen Chang Qingfeng Song Shuyue Wang Danny Tholen Yu Wang Changpeng xin Guangyong Zheng Honglong Zhao Xin-Guang Zhu | 2017 | Frontiers of Electrical and Electronic Engineering in China2017，5，3： | 3 |
| 12 | Effect of casting speed on surface quality of horizontal direct chill casting 7075 aluminum alloy ingot显示文摘7075 aluminum alloy ingot with the diameter of 100 mm has been produced by hor-izontal direct chill casting in different casting speed. The effect of the casting speed on the ingot surface and subsurface layer was studied by surface observation and subsurface structure analysis. It was found that increasing the casting speed results in the adding of segregation knots in the ingot surface. The thickness of the dendrite microstructure layer in the subsurface reduces with increasing the casting speed. And the elements of Zn,Cu and Mg enrich in the coarse dendrite microstructure layer of the ingot. | Qingfeng ZHU Zhihao ZHAO Jianzhong CUI Xiangjie WANG Ke QIN | 2011 | Acta Metallurgica Sinica(English Letters)2011，24，5： | 3 |
| 13 | Pathogenic mutations of nuclear genes associated with mitochondrial disorders显示文摘Mitochondrial 混乱是与 mitochondrial 机能障碍联系的临床的显型,它能被变化在 mitochondrial DNA (mtDNA ) 或原子基因引起。在这评论,我们总结了与 mitochondrial 混乱联系的原子基因的病原的变化。这些原子基因编码, mitochondrial 的部件翻译机械和氧化 phosphorylation 的集会因素,那建筑群。分子的机制,原子修饰词基因调制 mtDNA 变化的 phenotypic 表示,详细被讨论。 | Xiaoyu Zhu Xuerui Peng Min-Xin Guan Qingfeng Yan | 2009 | Acta Biochimica et Biophysica Sinica2009，41，3： | 3 |
| 14 | Origin of inhomogeneity in spark plasma sintered bismuth antimony telluride thermoelectric nanocomposites显示文摘Anisotropy and inhomogeneity are ubiquitous in spark plasma sintered thermoelectric devices.However,the origin of inhomogeneity in thermoelectric nanocomposites has rarely been investigated so far.Herein,we systematically study the impact of inhomogeneity in spark plasma sintered bismuth antimony telluride(BiSbTe)thermoelectric nanocomposites fabricated from solution-synthesized nanoplates.The figure of merit can reach 1.18,which,however,can be overestimated to 1.88 without considering the inhomogeneity.Our study reveals that the inhomogeneity in thermoelectric properties is attributed to the non-uniformity of porosity,textures and elemental distribution from electron backscatter diffraction and energy-dispersive spectroscopy characterizations.This finding suggests that the optimization of bulk material homogeneity should also be actively pursued in any future thermoelectric material research. | Enzheng Shi Shuang Cui Nicholas Kempf Qingfeng Xing Thomas Chasapis Huazhang Zhu Zhe Li Je-Hyeong Bahk G.Jeffrey Snyder Yanliang Zhang Renkun Chen Yue Wu | 2020 | Nano Research2020，13，5： | 2 |
| 15 | Hot-top direct chill casting assisted by a twin-cooling field:Improving the ingot quality of a large-size 2024 Al alloy显示文摘Microstructure inhomogeneity and negative segregation have long been challenges for large-size alloy ingots,directly affecting the downstream processing and final performance of products.Here,we used2024 aluminum alloy as a model alloy to propose a technique,named double-cooling field casting,i.e.,one 2024 Al alloy rod(Φ20 mm)at room temperature was introduced into the melt along the central axis of the hot-top with the protection of a thermal-insulation tube during the direct chill(DC)casting process of aΦ300 mm 2024 Al alloy ingot.The results show that the introduction of the same alloy solid insert has a remarkable influence on refining grains in the center region of the ingot,reducing negative centerline segregation and decreasing the depth of the center part of the sump.With the application of the 2024 Al insert,the mean size of equiaxed grains at the center part of the ingot decreased from1204±132μm to 721±69μm.The relative deviation of the Cu and Mg main solutes reduced from-0.062 and-0.054 to-0.03 and-0.024,respectively,and the sump depth decreased from 280 mm to242 mm.Moreover,the shape of the solidification front was changed from‘V’-shaped to‘W’-shaped.The ingot quality was thus improved,mainly arising from the dissolution of the cold 2024 Al insert at a proper position of the hot-top counteracting some latent heat of solidification of the ingot,dissipating the heat of the central part of the hot-top by conducting the 2024 Al insert to the outside,and providing extra-nuclei from the unmoltenα-Al particles of the insert. | Cheng Zhu Zhihao Zhao Qingfeng Zhu Gaosong Wang Yubo Zuo Qiangqiang Li Gaowu Qin | 2022 | Journal of Materials Science & Technology2022，，17： | 1 |
| 16 | Author Correction:Evolutionarily conservative and non-conservative regulatory networks during primate interneuron development revealed by single-cell RNA and ATAC sequencing显示文摘Correction to:Cell Research http://gffzzd3cc09b8251d45dfs9nkvcnx0vpn66fxf.ffgz.tsg.suse.edu.cn/10.1038/s41422-022-00635-9,published online 10 March 2022 We found that the information in the original Supplementary Figs.S2–S4 was not fully displayed due to an error in the image upload.The correct images are shown below for better display.These corrections do not affect the description of the results or the conclusion of this work.No change of the original figure legends is needed.We apologize for the mistake.The original article has been corrected. | Ziqi Zhao Dan Zhang Fuqiang Yang Mingrui Xu Shaoli Zhao Taotao Pan Chuanyu Liu Yongjie Liu Qingfeng Wu Qiang Tu Ping Zhou Rong Li Jia Kang Lan Zhu Fei Gao Yaqing Wang Zhiheng Xu | 2023 | Cell Research2023，33，7： | 1 |
| 17 | Biomass Homogeneity Reinforced Carbon Aerogels Derived Functional Phase-Change Materials for Solar–Thermal Energy Conversion and Storage显示文摘We deviseda functional form stable compositephase-change materials(PCMs)toachieve a three-dimensional(3D)interconnectedporous carbon aerogel structure for encapsulating polyethyleneglycol(PEG).Anovelhomogeneity reinforced carbonaerogel witha well-interconnected porous structure was constructed bycombining a flexible carbonresource from biomass guar gum with hard-brittle carbonfrom polyimide,to overcome severeshrinkage andpoor mechanical performance of traditionalcarbon aerogel.Thesupportingcarbon aerogel-encapsulated PEG produced thenovel composite PCMswithgood structure stability andcomprehensive energy storage performance.Theresults showed thatthecomposite PCMsdisplayed awell-defined 3Dinterconnected structure,and theirenergy storage capacities were 171.5 and169.5 J/g,which changed onlyslightlyafter 100 thermalcycles,andthe compositescould maintainthe equilibrium temperature at50.0−58.1℃ for about 760.3 s.The thermal conductivityofthe compositescould reach0.62 W m^(−1) K^(−1),which effectively enhanced the thermalresponse rate.And thecomposite PCMs exhibited good leakage-proof performance andexcellent light–thermal conversion.The compressive strengthof thecomposite PCMscan improveupto 1.602 MPa.Results indicatethatthisstrategy canbe efficiently usedtodevelop novel composite PCMswithimproved comprehensive thermalperformance and high light–thermal conversion. | Qingfeng Zhang Tingfeng Xia Qihan Zhang Yucao Zhu Huanzhi Zhang Fen Xu Lixian Sun Xiaodong Wang Yongpeng Xia Xiangcheng Lin Hongliang Peng Pengru Huang Yongjin Zou Hailiang Chu Bin Li | 2023 | Energy & Environmental Materials2023，6，1： | 1 |
| 18 | A joint call for actions to advance taxonomy in China显示文摘Taxonomy plays an important role in understanding the origin, evolution, and ecological functionality of biodiversity. There are large number of unknown species yet to be described by taxonomists, which together with their ecosystem services cannot be effectively protected prior to description. Despite this, taxonomy has been increasingly underrated insufficient funds and permanent positions to retain young talents. Further, the impact factordriven evaluation systems in China exacerbate this downward trend, so alternative evaluation metrics are urgently necessary. When the current generation of outstanding taxonomists retires,there will be too few remaining taxonomists left to train the next generation. In light of these challenges, all co-authors worked together on this paper to analyze the current situation of taxonomy and put out a joint call for immediate actions to advance taxonomy in China. | Chaodong Zhu Arong Luo Ming Bai Michael COrr Zhonge Hou Siqin Ge Jun Chen Yibo Hu Xuming Zhou Gexia Qiao Hongzhi Kong Limin Lu Xiaohua Jin Lei Cai Xinli Wei Ruilin Zhao Wei Miao Qingfeng Wang Zhongli Sha Qiang Lin Meng Qu Jianping Jiang Jiatang Li Jing Che Xuelong Jiang Xiaoyong Chen Lianming Gao Zongxin Ren Chunlei Xiang Shixiao Luo Donghui Wu Dong Liu Yanqiong Peng Tao Su Chenyang Cai Tianqi Zhu Wanzhi Cai Xingyue Liu Hu Li Huaijun Xue Zhen Ye Xuexin Chen Pu Tang Shujun Wei Hong Pang Qiang Xie Feng Zhang Feng Zhang Xianjin Peng Aibing Zhang Taiping Gao Changfa Zhou Chen Shao Libin Ma Zhaoming Wei Yunxia Luan Ziwei Yin Wu Dai Cong Wei Xiaolei Huang Jingxian Liu Xiangsheng Chen Tianci Yi Zhisheng Zhang Zhulidezi Aishan Qin Li Hongying Hu | 2022 | Zoological Systematics2022，47，3： | 1 |
| 19 | Experimental investigation of heat transport and solidification during low frequency electromagnetic hot-top casting of 6063 aluminum alloy显示文摘 | Xiangjie Wang Haitao Zhang Yubo Zuo Zhihao Zhao Qingfeng Zhu Jianzhong Cui | 2008 | Materials Science & Engineering A2008，，1： | 1 |
| 20 | Genome-wide profiling of histone H3 lysine 27 trimethylation and its modification in response to chilling stress in grapevine leaves显示文摘Histone H3 lysine 27 trimethylation(H3K27me3) is a histone modification associated with transcriptional repression. However, insights into the genome-wide pattern of H3K27me3 in grapevines are limited. Here, anti-H3K27 chromatin immunoprecipitation(ChIP), high-throughput sequencing, and transcriptome analysis were performed using leaves of Vitis amurensis. The leaves were treated at 4°C for 2 h and 24 h and used to investigate changes in H3K27me3 under chilling treatment. The results show that H3K27me3 is well-distributed both in gene regions(-50%) and in the intergenic region(-50%) in the grapevine genome(Vitis vinifera ‘Pinot Noir PN40024'). H3K27me3 was found to be localized in8 368 annotated gene regions in all detected samples(leaves at normal temperature and under chilling treatments) and mainly enriched in gene bodies with the adjacent promoter and downstream areas. The short-term chilling treatments(4°C for 2 h) induced 2 793 gains and 305losses in H3K27me3 modification. Subsequently, 97.3% of the alterations were restored to original levels after 24 h treatment. The ChIP-qPCR for five differential peaks showed similar results to the data for ChIP-seq, indicating that the chilling-induced H3K27me3 modification is reliable.Integrative analysis of transcriptome and ChIP-seq results showed that the expression of H3K27me3 target genes was significantly lower than those of non-target genes, indicating transcriptional repression of H3K27me3 in grapevine leaves. Furthermore, histone methylation alterations were detected in 82 genes and were related to either repression or activation of their expression during chilling stress. The findings provide the genome-wide H3K27me3 patterns in grapevines and shed light on uncovering its regulation in chilling stress responses. | Zhenfei Zhu Qingyun Li Duncan Kiragu Gichuki Yujun Hou Yuanshuang Liu Huimin Zhou Chen Xu Linchuan Fang Linzhong Gong Beibei Zheng Wei Duan Peige Fan Qingfeng Wang Haiping Xin | 2023 | Horticultural Plant Journal2023，9，3： | 1 |
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