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| 1 | An individualized immune signature of pretreatment biopsies predicts pathological complete response to neoadjuvant chemoradiotherapy and outcomes in patients with esophageal squamous cell carcinoma显示文摘No clinically available biomarkers can predict pathological complete response(pCR)for esophageal squamous cell carcinomas(ESCCs)with neoadjuvant chemoradiotherapy(nCRT).Considering that antitumor immunity status is an important determinant for nCRT,we performed an integrative analysis of immune-related gene profiles from pretreatment biopsies and constructed the first individualized immune signature for pCR and outcome prediction of ESCCs through a multicenter analysis.During the discovery phase,14 differentially expressed immune-related genes(DEIGs)with greater than a twofold change between pCRs and less than pCRs( | Chaoqi Zhang Guochao Zhang Nan Sun Zhen Zhang Liyan Xue Zhihui Zhang Haijun Yang Yuejun Luo Xiaoli Zheng Yonglei Zhang Yufen Yuan Ruixue Lei Zhaoyang Yang Bo Zheng Le Wang Yun Che Feng Wang Sihui Wang Shugeng Gao Qi Xue Yi Zhang Jie He | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 7 |
| 2 | Polarization-sensitive and wide-spectrum photovoltaic detector based on quasi-1D ZrGeTe_(4)nanoribbon显示文摘Low-dimensional semiconductors with in-plane anisotropy and narrow bandgap have been extensively applied to polarized detection in the near-infrared(NIR)region.However,the narrow bandgap can cause noise owing to the high dark current in photodetectors.This article reports quasi-1D ZrGeTe_(4)nanoribbonbased photodetectors with low dark current and broadband polarization detection.The photodetector was fabricated by evaporating 50-nm-thick Au electrodes on a ZrGeTe_(4)nanoribbon.Benefiting from the photovoltaic characteristics in the ZrGeTe_(4)nanoribbon and Au electrodes,these photodetectors can operate without bias voltage,with decreased dark current,and improved device performance.Furthermore,the quasi-1D ZrGeTe_(4)nanoribbon-based photodetectors demonstrate a polarization sensitivity in a broadband from visible(VIS)to the NIR region,such as a high photoresponsivity of 625.65 mA W1,large external quantum efficiency of 145.9%at 532 nm,and photocurrent anisotropy ratio of 2.04 at 1064 nm.They exhibit a novel perpendicular optical reversal of 90in polarization-sensitive photodetection,angle-resolved absorption spectra,and azimuth-dependent reflectance difference microscopy(ADRDM)from VIS to the NIR region,as opposed to other nanoribbon-based polarization-sensitive photodetectors.This work paves the way for utilizing photovoltaic photodetectors based on low-dimensional materials for broad-spectrum polarized photodetection. | Ruixue Bai Tao Xiong Jinshu Zhou Yue-Yang Liu Wanfu Shen Chunguang Hu Faguang Yan Kaiyou Wang Dahai Wei Jingbo Li Juehan Yang Zhongming Wei | 2022 | InfoMat2022，4，3： | 2 |
| 3 | Cell Membrane-camouflaged Multi-functional Dendritic Large Pore Mesoporous Silica Nanoparticles for Combined Photothermal Therapy and Radiotherapy of Cancer显示文摘Combining photothermal therapy and radiotherapy(PTT-RT) with reducing tumor hypoxia acts as an important antitumor modality. However, it is a great challenge to realize photothermal therapy, radiotherapy and exogenous oxygen supply in one nanosystem. To realize a combination of the three functions, we fabricated a red blood cell membrane(RBCm)-camouflaged, red blood cell content(RBCc) and the copper sulfide(CuS) co-loaded dendritic large pore mesoporous silica nanoparticle(DLMSN/CuS/RBCc/ RBCm). The cell membrane coating endowed the nanoparticles with good stability in the physiological environment, and CuS allowed the nanoparticle exhibiting good photothermal and radiosensitization properties. RBCc loaded nanoparticle DLMSN/CuS/RBCc enhanced superior anti-tumor effect than DLMSN/CuS during combined PTT-RT therapy because the introduction of RBCc increased the exogenous oxygen supply. The in vitro study further demonstrated that the combination of photothermal therapy and radiotherapy induced superior antitumor efficacy than single therapy. Our work thus presents a unique multifunctional nanoscale platform favorable for combined PTT and RT. | WU Liting XIN Yujia GUO Zhaoyang GAO Wei ZHU Yanpeng WANG Yinsong RAN Ruixue YANG Xiaoying | 2022 | Chemical Research in Chinese Universities2022，38，2： | 1 |
| 4 | Metabolic dysfunction-associated fatty liver disease: from basic research to clinical application显示文摘The increasing burden of non-alcoholic fatty liver disease:Non-alcoholic fatty liver disease(NAFLD)is the_most common causeofchronicliverdisease in the world.NAFLD encompasses,a spectrum of liver,disease,ranging from simple hepatic steatosis to non-alcoholic steatohepatitis(NASH),fibrosis,cirrhosis,and hepatocellular carcinoma(HCC). | Ruixu Yang Qian Jin Jiangao Fan | 2022 | Chinese Medical Journal2022，，10： | 1 |
| 5 | Prediction of adolescent subjective well being: A machine learning approach显示文摘Background Subjective well-being(SWB),also known as happiness,plays an important role in evaluating both mental and physical health.Adolescents deserve specific attention because they are under a great variety of stresses and are at risk for mental disorders during adulthood.Aim The present paper aims to predict undergraduate students1 SWB by machine learning method.Methods Gradient Boosting Classifier which was an innovative yet validated machine learning approach was used to analyse data from 10518 Chinese adolescents.The online survey included 298 factors such as depression and personality.Quality control procedure was used to minimise biases due to online survey reports.We applied feature selection to achieve the balance between optimal prediction and result interpretation.Results The top 20 happiness risks and protective factors were finally brought into the predicting model.Approximately 90%individuals'SWB can be predicted correctly,and the sensitivity and specificity were about 92%and 90%,respectively.Conclusions This result identifies at-risk individuals according to new characteristics and established the foundation for adolescent prevention strategies. | Naixin Zhang Chuanxin Liu Zhixuan Chen Lin An Decheng Ren Fan Yuan Ruixue Yuan Lei Ji Yan Bi Zhenming Guo Gaini Ma Fei Xu Fengping Yang Liping Zhu Gabirel Robert Yifeng Xu Lin He Bo Bai Tao Yu Guang He | 2019 | General Psychiatry2019，32，5： | 1 |
| 6 | Microstructures, mechanical properties and in vitro corrosion behavior of biodegradable Zn alloys microalloyed with Al, Mn, Cu, Ag and Li elements显示文摘In this work,Zn microalloyed with Al,Mn,Cu,Ag and Li was cast,annealed and extruded.The results showed that addition of multiple trace elements causes significant change in the microstructures,mechanical properties and corrosion behavior of Zn-0.1Al-0.1Mn-0.1Cu-0.1Ag(^(1)ZM),Zn-0.1Al-0.1Mn-0.1Cu0.1Ag-0.1Li(^(2)ZM-0.1Li)and Zn-0.1Al-0.1Mn-0.1Cu-0.1Ag-0.35Li(^(3)ZM-0.35Li)alloys.Two ternary phases with the approximate compositions of Al_(13)Mn_(3)Zn_(34) and Al_(10)MnZn_(89) phases are formed in the casting and annealing processes of these alloys,respectively.Wavyβ-LiZn_(4) lamellae that have not been extensively reported are precipitated from the primary Zn dendrites in the casting process of ZM-0.35Li alloy.Also,Zn laths are precipitated from the eutecticβ-LiZn_(4) phase in the annealing process of ZM-0.35Li alloy.The above-mentioned phases are crushed or elongated in the as-extruded alloys,which play an important role in improving the strength of the alloys.All the as-extruded alloys have typical(0001)basal texture,accompanied with relatively low{0001}<1120>slip and high{1012}<1011>twinning Schmid factors,which are advantageous and disadvantageous to the strength enhancement of the alloys,respectively.All the as-cast alloys exhibit poor mechanical properties,especially low ductility.The as-extruded ZM alloy exhibits ultrahigh ductility,with an elongation of up to 82.2%±2.94%.The as-extruded ZM0.35Li alloy shows the best comprehensive mechanical properties,with yield strength,ultimate tensile strength,elongation and hardness of 380±1.6 MPa,449±7.4 MPa,62.3%±4.63%and 98±1.4 HV,respectively.Electrochemical corrosion rates of the ZM,ZM-0.1Li and ZM-0.35Li alloys are 0.241±0.004,0.206±0.006 and 0.189±0.008 mm/year,respectively.In vitro immersion corrosion rates(after 26 d in SBF solution)of them are 0.134±0.005,0.125±0.004 and 0.121±0.003 mm/year,respectively.The as-extruded ZM-0.35Li alloy exhibits the best corrosion resistance. | Lei Li Huanzheng Jiao Congfu Liu Lin Yang Yusong Suo Ruixue Zhang Tie Liu Jianzhong Cui | 2022 | Journal of Materials Science & Technology2022，，8： | 1 |
| 7 | Characterization ofα_(2)Precipitates in Ti–6Al and Ti–8Al Binary Alloys:A Comparative Investigation显示文摘Transmission electron microscopy(TEM)and atom probe tomography(APT)techniques were used to investigate the nanoscale orderedα_(2)(Ti_(3)Al)precipitates in Ti–Al binary alloys.Ti–6Al and Ti–8Al binary alloys were solution treated and aged to obtain Widmanstatten microstructure and promoteα_(2)precipitates.The TEM results displayed strong short-range ordering ofα_(2)precipitates in Ti–8Al alloy,while no evidence of the superlattice reflections ofα_(2)in Ti–6Al alloy.The results acquired from APT showed theα_(2)clusters and atoms distribution at the interface between the matrix andα_(2)precipitates.The size and morphology ofα_(2)particles in Ti–8Al alloy,respectively,obtained by TEM and APT are closely consistent.Meanwhile,the APT results displayed tiny size clusters in Ti–6Al alloy,which supposed to give evidence of the initial ordering process ofα_(2)precipitates in the absence of correlative results from TEM. | Sabry S.Youssef Xiaodong Zheng Yingjie Ma Sensen Huang Min Qi Jianke Qiu Ruixue Zhang Peitao Hua Shijian Zheng Jiafeng Lei Rui Yang | 2021 | Acta Metallurgica Sinica(English Letters)2021，34，5： | 1 |
| 8 | Investigation ongeneration performance for tubular direct methanol fuel cell显示文摘 | Tang Dong Zhang Yang Duan Ruixue | 2011 | Advanced Materials Research2011，，： | 1 |
| 9 | Numerical study of double diffusive mixed convection around a heated cylinder in an enclosure显示文摘 | Hongtao Xu Ruixue Xiao Fariborz Karimi Mo Yang Yuwen Zhang | 2014 | International Journal of Thermal Sciences2014，，： | 1 |
| 10 | Hollow Fe_(2)O_(3)/Co_(3)O_(4)microcubes derived from metal-organic framework for enhanced sensing performance towards acetone显示文摘In this work,hollow Fe_(2)O_(3)/Co_(3)O_(4)microcubes have been successfully synthesized through a hydrothermal method followed by an annealing process using metal-organic framework of Prussian blue as a soft template.The morphologies,microstructures,surface area and element compositions have been carefully characterized by a series of techniques.Meanwhile,compared with that of pure Fe_(2)O_(3)and Co_(3)O_(4),the gas sensor based on the hollow microcubes exhibits enhanced sensing performances towards acetone,e.g.,a higher response of 21.2 and a shorter response time of 5 s towards 20 ppm acetone at a relatively low working temperature of 200℃.Moreover,the hollow microcubes-based gas sensor still shows perfect long-term stability,excellent repeatability and the ability of sub-ppm level detection,which provides a possibility for its application in real life.The enhanced gas sensing performances can be attributed to the hollow structure with a high surface area and the formed p-n heterojunctions within the microcubes. | Ruixue Mo Dongqiang Han Zeng Ren Dazhuang Yang Fei Wang Caolong Li | 2021 | Chinese Chemical Letters2021，32，11： | 1 |
| 11 | Tensile Behavior of Strain Hardening Cementitious Composites (SHCC) Containing Reactive Recycled Powder from Various C&D Waste显示文摘This work investigates the feasibility of utilizing reactive recycled powder(RP)from construction and demolition(C&D)waste as supplementary cementitious material(SCM)to achieve a ductile strain hardening cementitious composites(SHCC).The recycled mortar powder(RMP)from mortar waste,recycled concrete powder(RCP)from concrete waste and recycled brick powder(RBP)from clay brick waste were first prepared,and the micro-properties and tensile behavior of SHCC containing various types and replacement ratios of RPs were determined.The incorporated RP promotes pozzolanic and filler effects,while the hydration products in cementitious materials decrease with RP incorporation;therefore,the incorporated RP decreases the compressive strength of SHCC.Attributed to the reduction in the matrix strength,the incorporated RP increases the crack-bridging extent and ductility of SHCC;the irregular micro-structure and high reactivity of RP also help the strain-hardening performance of the prepared SHCC.In addition,the strainhardening performance of SHCC containing RMP and RBP is surperior to that of SHCC with RCP and is slightly lower than that of SHCC with fly ash(FA);for instance,the ultimate strain of SHCC containing 54%FA,RMP,RCP and RBP is 3.67%,3.61%,2.52%and 3.53%,respectively.In addition,the strain-hardening behavior of an SHCC doubled mix with FA and RMP or RBP has a similar ultimate strain and a higher ultimate stress than SHCC containing only FA. | Ruixue Wu Tiejun Zhao Peng Zhang Dingyi Yang Miao Liu Zhiming Ma | 2021 | Journal of Renewable Materials2021，9，4： | 1 |
| 12 | Formamidinium-incorporated Dion-Jacobson phase 2D perovskites for highly efficient and stable photovoltaics显示文摘Dion-Jacobson phase two-dimensional(DJ 2D)perovskites,recently attracting considerable interests,exhibit excellent environmental stability and structural tunability,but their solar cells still offer unsatisfactory power conversion efficiencies(PCEs).Herein,we develop DJ 2D perovskites employing formamidinium(FA+)as a ternary cation in the perovskite cages((PDA)(FA)x(MA)3-xPb4 I13,χ=0,0.15,0.3 and 0.6,PDA=1,3-propanediammonium)for highly efficient and stable perovskite solar cells(PSCs).We found that the DJ 2D perovskite with a 10%FA+fraction presents improved crystallinity,preferred vertical orientation,and longer charge carrier lifetime compared to that without FA+doping.As a result,the FAdoped DJ 2D PSCs exhibit a champion PCE of 14.74%with superior device stability.The unencapsulated devices sustain over 92%of its initial PCE after storage at a constant relative humidity(RH)of 65%for 6000 h,90%by heat at 85℃in air for 800 h,and 94%under 1-sun illumination for 5000 h.These findings demonstrate that the incorporation of FA cation into the DJ 2D perovskite is a promising strategy to develop highly efficient and stable DJ 2D PSCs. | Sajjad Ahmad Wei Yu Ruixue Lu Yang Liu Tonggang Jiu Shuping Pang Xin Guo Can Li | 2021 | Journal of Energy Chemistry2021，30，6： | 1 |
| 13 | Phototriggered Formation of a Supramolecular Polymer Network Based on Orthogonal H-Bonding and Host-Guest Recognition显示文摘Supramolecular polymer networks(SPNs)have gained increasing research attention due to their reversible and tunable nature in the preparation of adaptive materials.The use of hierarchical self-assembly techniques is an emerging strategy for the fabrication of smart supramolecular polymer networks,but corresponding study is still rare.Herein,we have reported a novel supramolecular polymer network through complementary host-guest interactions and phototriggered quadruple H-bonding cross-linking.Specifically,we design and synthesize an H1G1-type monomer consisting of a benzo-21-crown-7(B21C7)host(H1),a dialkylammonium salt guest(G1)and a photolabile o-nitrobenzyl ether protected ureidopyrimidinone(Upy)moiety.B21C7 and ammonium moieties can first form a linear supramolecular polymer through complementary host-guest interactions.Under photoirradiation,the Upy groups on the SP side chains were released,and the obtained linear supramolecular polymer could be further transformed into SPN through a quadruple H-bonding cross-linking.Meanwhile,the in situ transformation in the solid state is also accompanied by pronounced enhancement in mechanical properties,which provides foundation for further application of materials in different scenarios. | BAI Ruixue YANG Xue ZHAO Jun ZHANG Zhaoming YAN Xuzhou | 2023 | Chemical Research in Chinese Universities2023，39，5： | 0 |
| 14 | Atomically dispersed Fe sites on hierarchically porous carbon nanoplates for oxygen reduction reaction显示文摘Developing cost-effective,robust and stable non-precious metal catalysts for oxygen reduction reaction(ORR) is of paramount importance for electrochemical energy conversion devices such as fuel cells and metal-air batteries.Although Fe-N-C single atom catalysts(SACs) have been hailed as the most promising candidate due to the optimal binding strength of ORR intermediates on the Fe-N_(4) sites,they suffer from serious mass transport limitations as microporous templates/substrates,i.e.,zeolitic imidazolate frameworks(ZIFs),are usually employed to host the active sites.Motivated by this challenge,we herein develop a hydrogen-bonded organic framework(HOF)-assisted pyrolysis strategy to construct hierarchical micro/mesoporous carbon nanoplates for the deposition of atomically dispersed Fe-N_(4) sites.Such a design is accomplished by employing HOF nanoplates assembled from 2-aminoterephthalic acid(NH_(2)-BDC) and p-phenylenediamine(PDA) as both soft templates and C,N precursors.Benefitting from the structural merits inherited from HOF templates,the optimized catalyst(denoted as Fe-N-C SAC-950) displays outstanding ORR activity with a high half-wave potential of 0.895 V(vs.reversible hydrogen electrode(RHE)) and a small overpotential of 356 mV at 10 mA cm^(-2) for the oxygen evolution reaction(OER).More excitingly,its application potential is further verified by delivering superb rechargeability and cycling stability with a nearly unfading charge-discharge gap of 0.72 V after 160 h.Molecular dynamics(MD) simulations reveal that micro/mesoporous structure is conducive to the rapid mass transfer of O_(2),thus enhancing the ORR performance.In situ Raman results further indicate that the conversion of O_(2) to~*O_(2)-the rate-determining step(RDS) for Fe-N-C SAC-950.This work will provide a versatile strategy to construct single atom catalysts with desirable catalytic properties. | Ruixue Zheng Qinglei Meng Hao Zhang Teng Li Di Yang Li Zhang Xiaolong Jia Changpeng Liu Jianbing Zhu Xiaozheng Duan Meiling Xiao Wei Xing | 2024 | Journal of Energy Chemistry2024，90，3： | 0 |
| 15 | Light-harvesting Complex Ⅱ Sensitized Oxide Photoanodes with Organic Acceptor Molecule as Electron Transfer Mediator显示文摘Dye sensitized solar cell(DSSC) is a promising thin film solar cell that has been widely investigated after its birth because of its advantages,such as flexibility,low-cost,easyfabrication and so on[1-3].For DSSCs,sensitizers play a core role due to their responsibility for the generation of the photo carriers resulted from light absorption and the transfer of the photo-generated electrons into semiconductor photoanodes[4]. | DONG Wenjing ZHANG Tianning LIU Kun SUN Ruixue HUANG Chanyan SUN Yan LIU Cheng CHEN Xin YANG Guoqiang YANG Chunhong DAI Ning | 2014 | Chemical Research in Chinese Universities2014，30，2： | 0 |
| 16 | Characterization of the core microflora and nutrient composition in packaged pasteurized milk products during storage显示文摘Pasteurized milk contains complex microbial communities affected by sterilization and storage conditions.This complex microflora may be the possible reason that pasteurized dairy products are highly prone to spoilage.In this study,packaged pasteurized milk products collected from dairy processing factories in China were stored at 0,4,10,15,and 25℃ for 0−15 days and subjected to microbial identification using high-throughput sequencing.Accordingly,6 phyla and 44 genera were identified as the dominant microbiota.Moreover,the changes in nutritional composition of the pasteurized milk,including in 16 free amino acids,7 taste values,and 8 chemical constituents,were analyzed using principal component and multi-factor analyses.The Pearson correlation analysis identified Pseudomonas,Aeromonas,Paenibacillus,and Serratia genera as the core functional microbiota that significantly affects the nutritional composition of pasteurized milk.Hence,the results provide a comprehensive understanding of the safety and shelf-life of stored pasteurized milk. | Ruixue Ding Shanshan Yang Lijuan Geng Yumeng Liu Baoping He Liyun Liu Xiqing Yue Rina Wu Junrui Wu | 2023 | Food Science and Human Wellness2023，12，4： | 0 |
| 17 | The relationships between step count and all-cause mortality and cardiovascular events:A doseresponse meta-analysis显示文摘Background:A goal of 10,000 steps per day is widely advocated,but there is little evidence to support that goal.Our purpose was to examine the doseresponse relationships between step count and all-cause mortality and cardiovascular disease risk.Methods:Cochrane Central Register of Controlled Trials,EMBASE,OVID,PubMed,Scopus,and Web of Science databases were systematically searched for studies published before July 9,2021,that evaluated the association between daily steps and at least 1 outcome.Results:Sixteen publications(12 related to all-cause mortality,5 related to cardiovascular disease;and 1 article contained 2 outcomes:both allcause death and cardiovascular events)were eligible for inclusion in the meta-analysis.There was evidence of a nonlinear doseresponse relationship between step count and risk of all-cause mortality or cardiovascular disease(p=0.002 and p=0.014 for nonlinearity,respectively).When we restricted the analyses to accelerometer-based studies,the third quartile had a 40.36%lower risk of all-cause mortality and a 35.05%lower risk of cardiovascular event than the first quartile(all-cause mortality:Q1=4183 steps/day,Q3=8959 steps/day;cardiovascular event:Q1=3500 steps/day,Q3=9500 steps/day;respectively).Conclusion:Our meta-analysis suggests inverse associations between higher step count and risk of premature death and cardiovascular events in middle-aged and older adults,with nonlinear doseresponse patterns. | Mingxin Sheng Junyue Yang Min Bao Tianzhi Chen Ruixue Cai Na Zhang Hongling Chen Minqi Liu Xueyu Wu Bowen Zhang Yiting Liu Jianqian Chao | 2021 | Journal of Sport and Health Science2021，10，6： | 0 |
| 18 | Effects of transport stress on immune response, physiological state, and WSSV concentration in the red swamp crayfish Procambarus clarkii显示文摘Transport is an essential part of the aquaculture and research of the main freshwater aquaculture crayfish Procambarus clarkii in China.However,transport is often accompanied by a low survival rate.Assessing the physiological state of P.clarkii before and after transport may discover the cause of this high mortality rate.In this study,ice-cold and exposed-to-air transport methods were compared using an array of parameters,including relative expression level of heat shock protein 70(HSP70),content of serum glucose and cortisol,immune parameters(enzyme and immune-related genes),and white spot syndrome virus(WSSV)concentration were investigated to understand the physiological state of P.clarkii before and after transport,as well as the cause of dying crayfish on days 5 and 7 after transport stress.Histological sections of hepatopancreas,gills,and intestines reflected pathological changes.The survival rate of crayfish with ice-cold transport was significantly higher than that with exposed-to-air transport,and mortality peaked at 3-9 days after transport stress.A prolonged response to oxidative stress and short-term immunosuppression was present after transport,and the trend of the WSSV concentration in the hepatopancreas was similar to the mortality rate of P.clarkii.The contents of serum glucose and cortisol,antioxidant enzymes and immune-related indexes,and the concentration of WSSV in hepatopancreas of dying crayfish were significantly higher than those of vibrant crayfish on the 5th and 7th days after transport.The hepatopancreas,intestines,and gills of dying crayfish had varying degrees of damage,and the hepatopancreas and intestines were severely damaged.The results suggested that the death of P.clarkii after transport stress is caused by oxidative stress,the imbalance of reactive oxygen species regulation,and decreased WSSV resistance,which eventually led to irreversible tissue damage.The increase of WSSV in the body of crayfish might be the direct cause of crayfish death. | Ruixue Shi Siqi Yang Qishuai Wang Long Zhang Yanhe Li | 2023 | Aquaculture and Fisheries2023，8，5： | 0 |
| 19 | Crystal structure of heliorhodopsin 48C12显示文摘Dear Editor,Heliorhodopsins(HeRs)are a new class of Microbial rhodopsins(MRs),with a low homology(<15%)to all other MRs and a unique membrane topology in which their N-termini face the intracellular side and C-termini face the extracellular side.1 To explore the photoactivation mechanism of HeRs,we sought to solve the structure of HeR 48C12(hereafter referred to as HeR).HeR protein was expressed in insect cells and purified by standard membrane purification methods(Supplementary information,Fig.S1a and Data S1).The purified HeR shows a monodispersed peak and exhibits a high thermostability(Tm=74°C,Supplementary information,Fig.S1b,c). | Yang Lu X.Edward Zhou Xiang Gao Na Wang Ruixue Xia Zhenmei Xu Yu Leng Yuying Shi Guangfu Wang Karsten Melcher H.Eric Xu Yuanzheng He | 2020 | Cell Research2020，30，1： | 0 |
| 20 | Metabolic profiles and morphological characteristics of leaf tips among different sweet potato(Ipomoea batatas Lam.)varieties显示文摘Sweet potato leaf tips have high nutritional value,and exploring the differences in the metabolic profiles of leaf tips among different sweet potato varieties can provide information to improve their qualities.In this study,a UPLC-Q-Exactive Orbitrap/MS-based untargeted metabolomics method was used to evaluate the metabolites in leaf tips of 32 sweet potato varieties.Three varieties with distinct overall metabolic profiles(A01,A02,and A03),two varieties with distinct profiles of phenolic acids(A20 and A18),and three varieties with distinct profiles of flavonoids(A05,A12,and A16)were identified.In addition,a total of 163 and 29 differentially expressed metabolites correlated with the color and leaf shape of sweet potato leaf tips,respectively,were identified through morphological characterization.Group comparison analysis of the phenotypic traits and a metabolite-phenotypic trait correlation analysis indicated that the color differences of sweet potato leaf tips were markedly associated with flavonoids.Also,the level of polyphenols was correlated with the leaf shape of sweet potato leaf tips,with lobed leaf types having higher levels of polyphenols than the entire leaf types.The findings on the metabolic profiles and differentially expressed metabolites associated with the morphology of sweet potato leaf tips can provide useful information for breeding sweet potato varieties with higher nutritional value. | Wenqing Tan Xinbo Guo Zhangying Wang Rong Zhang Chaochen Tang Bingzhi Jiang Ruixue Jia Yuanyuan Deng Shaohai Yang Jingyi Chen | 2024 | Journal of Integrative Agriculture2024，23，2： | 0 |
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