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| 1 | Crustal accretion and reworking processes of micro-continental massifs within orogenic belt:A case study of the Erguna Massif,NE China显示文摘This paper summarizes the geochronological, geochemical and zircon Hf isotopic data for Mesozoic granitoids within the Erguna Massif, NE China, and discusses the spatial-temporal variation of zircon Hf isotopic compositions, with the aim of constraining the accretion and reworking processes of continental crust within the Erguna Massif, and shedding light on the crustal evolution of the eastern segment of the Central Asian Orogenic Belt. Based on the zircon U-Pb dating results, the Mesozoic granitic magmatisms within the Erguna Massif can be subdivided into five stages: Early-Middle Triassic(249–237 Ma), Late Triassic(229–201 Ma), Early-Middle Jurassic(199–171 Ma), Late Jurassic(155–149 Ma), and Early Cretaceous(145–125 Ma).The Triassic to Early-Middle Jurassic granitoids are mainly I-type granites and minor adakitic rocks, whereas the Late Jurassic to Early Cretaceous granitoids are mainly A-type granites. This change in magmatism is consistent with the southward subduction of the Mongol-Okhotsk oceanic plate and subsequent collision and crustal thickening, followed by post-collision extension. Zircon Hf isotopic data indicate that crustal accretion of the Erguna Massif occurred in the Mesoproterozoic and Neoproterozoic. ZirconεHf(t) values increase gradually over time, whereas two-stage model(TDM2) ages decrease throughout the Mesozoic. The latter result indicates a change in the source of granitic magmas from the melting of ancient crust to more juvenile crust. Zircon εHf(t)values also exhibit spatial variations, with values decreasing northwards, whereas TDM2 ages increase. This pattern suggests that,moving from south to north, there is an increasing component of ancient crustal material within the lower continental crust of the Erguna Massif. Even if at the same latitude, the zircon Hf isotopic compositions are also inconsistent. These results reveal lateral and vertical heterogeneities in the lower continental crust of the Erguna Massif during the Mesozoic, which we use as the basis of a structural and tectonic model for this region. | SUN ChenYang TANG Jie XU WenLiang LI Yu ZHAO Shuo | 2017 | Science China Earth Sciences2017，60，7： | 10 |
| 2 | Crustal Accretion and Reworking within the Khanka Massif: Evidence from Hf Isotopes of Zircons in Phanerozoic Granitoids显示文摘This paper presents a synthesis and analysis of geochronological, geochemical, and zircon Hf isotopic data of Phanerozoic granitoids within the Khanka massif, with the aim of revealing the accretion and reworking processes of continental crust within the massif. Zircon U-Pb dating indicates that Phanerozoic granitic magmatism within the Khanka massif can be subdivided into eight stages: Late Cambrian, Middle–Late Ordovician, Middle Silurian, Late Carboniferous, Early Permian, Middle–Late Permian to Early Triassic, Late Triassic–Early Jurassic, and Early Cretaceous. The zircon Hf isotopic compositions reveal that crustal accretionary events took place mainly in the Mesoproterozoic and Neoproterozoic. Through time, the zircon ε_(Hf)(t) values gradually increase, indicating that the Phanerozoic granitic magmas were derived from the melting of progressively less ancient and more juvenile crust. The zircon ε_(Hf)(t) values exhibit a gradual decrease with the increases in latitude, which implies that the amounts of ancient crustal components within the lower continental crust of the Khanka massif increased from south to north. At the same latitude range, the zircon Hf isotopic compositions also display some variations. We conclude, therefore, that significant horizontal and vertical heterogeneities existed in the lower continental crust of the Khanka massif during the Phanerozoic. | Xiaoming Zhang Wenliang Xu Chenyang Sun Ting Xu Feng Wang | 2018 | Journal of Earth Science2018，29，2： | 3 |
| 3 | Improved design of online fault diagnoser for partially observed Petri nets with generalized mutual exclusion constraints显示文摘This paper investigates the fault detection problem for discrete event systems(DESs) which can be modeled by partially observed Petri nets(POPNs). To overcome the problem of low diagnosability in the POPN online fault diagnoser in current use,an improved online fault diagnosis algorithm that integrates generalized mutual exclusion constraints(GMECs) and integer linear programming(ILP) is proposed. Assume that the POPN structure and its initial markings are known, and the faults are modeled as unobservable transitions. First, the event sequence is observed and recorded. GMEC is used for elementary diagnosis of the system behavior, then the ILP problem of POPN is solved for further diagnosis. Finally, an example of a real DES to test the new fault diagnoser is analyzed. The proposed algorithm increases the diagnosability of the DES remarkably, and the effectiveness of the new algorithm integrating GMEC and ILP is verified. | Jiufu Liu Wenliang Liu Jianyong Zhou Yan Sun Zhisheng Wang | 2017 | Journal of Systems Engineering and Electronics2017，28，5： | 2 |
| 4 | CO_(2)emission and source partitioning from carbonate and non-carbonate soils during incubation显示文摘The accurate quantification and source partitioning of CO_(2)emitted from carbonate(i.e.,Haplustalf)and non-carbonate(i.e.,Hapludult)soils are critically important for understanding terrestrial carbon(C)cycling.The two main methods to capture CO_(2)released from soils are the alkali trap method and the direct gas sampling method.A 25-d laboratory incubation experiment was conducted to compare the efficacies of these two methods to analyze CO_(2)emissions from the non-carbonate and carbonate-rich soils.An isotopic fraction was introduced into the calculations to determine the impacts on partitioning of the sources of CO_(2)into soil organic carbon(SOC)and soil inorganic carbon(SIC)and into C3 and/or C4 plant-derived SOC.The results indicated that CO_(2)emissions from the non-carbonate soil measured using the alkali trap and gas sampling methods were not significantly different.For the carbonate-rich soil,the CO_(2)emission measured using the alkali trap method was significantly higher than that measured using the gas sampling method from the 14 th day of incubation onwards.Although SOC and SIC each accounted for about 50%of total soil C in the carbonate-rich soil,SOC decomposition contributed 57%–72%of the total CO_(2)emitted.For both non-carbonate and carbonate-rich soils,the SOC derived from C4 plants decomposed faster than that originated from C3 plants.We propose that for carbonate soil,CO_(2)emission may be overestimated using the alkali trap method because of decreasing CO_(2)pressure within the incubation jar,but underestimated using the direct gas sampling method.The gas sampling interval and ambient air may be important sources of error,and steps should be taken to mitigate errors related to these factors in soil incubation and CO_(2)quantification studies. | Yi ZHAO Roland BOL Zhaoan SUN Yuping ZHUGE Xiaoxia SHI Wenliang WU Fanqiao MENG | 2022 | Pedosphere2022，32，3： | 1 |
| 5 | Determination of six volatile organic compounds in the vapour phase of cigarette smoke by adsorption/thermal desorption and gas chromatography/mass spectrometry 显示文摘 | SUN Wenliang PU Junqing XIE Wenyan | 2004 | CORESTA2004，18，： | 1 |
| 6 | Investigating mechanisms of collagen thermal denaturation by high resolution second-harmonic generation imaging 显示文摘 | Sun Yen Chen Wenliang Lin Sungjan | 2006 | Biophys J2006，91，7： | 1 |
| 7 | Community of extremely halophilic bacteria in historic Dagong Brine Well in southwestern China显示文摘 | Wenliang Xiang Jianhua Guo Wei Feng Min Huang Hao Chen Jian Zhao Jie Zhang Zhirong Yang Qun Sun | 2008 | World Journal of Microbiology and Biotechnology2008，，10： | 1 |
| 8 | Nimodipine semi-solid capsul-es containing solid dispersion for improving dissolution 显示文摘 | Sun Y Rui Y Wenliang Z | 2008 | Int JPharm2008，359，12： | 1 |
| 9 | Modified similarity metric for non-local means algorithm 显示文摘 | SUN Weifeng PENG Yuhua HWANG Wenliang | 2009 | Electronics Letters(S0013-5194)2009，45，25： | 1 |
| 10 | Conversion of CO_(2) and H_(2) into propane over InZrO_(x) and SSZ-13 composite catalyst显示文摘Direct converting carbon dioxide into hydrocarbon fuels and value-added chemicals would offer a very attractive approach for efficient utilization of CO_(2) as a carbon resource.Although,olefins,aromatics and gasoline have been successfully synthesized by CO_(2) hydrogenation,highly selective conversion of CO_(2) and H_(2) into C_(2+)hydrocarbon is still challenging due to a high C-C coupling barrier and inhibiting the production of other long-chain hydrocarbons.Here,we report a composite catalyst made of InZrO_(x) and SSZ-13 molecular sieve(InZrO_(x)+SSZ-13),which exhibits 74.5% propane selectivity at 623 K.The 8-MR micropores and the higher strength of the acid for SSZ-13 benefit the formation of propane.Compared with pure InO_(x) and m-ZrO_(2) the composite oxide InZrO_(x) containing more oxygen vacancies,exhibits to be more readily reduced by H_(2) and easier to adsorb and desorb CO_(2) within the reaction temperature.All those could be beneficial to the activation and conversion of H_(2) and CO_(2).The catalytic performance of InZrO_(x)+SSZ-13 in CO_(2) hydrogenation provides a potential for production of propane. | Zhaopeng Liu Youming Ni Tantan Sun Wenliang Zhu Zhongmin Liu | 2021 | Journal of Energy Chemistry2021，30，3： | 1 |
| 11 | TNFα inhibitor C87 sensitizes EGFRvⅢ transfected glioblastoma cells to gefitinib by a concurrent blockade of TNFα signaling显示文摘Objective: More than half of human glioblastomas show EGFR gene amplification and mutation, but EGFR inhibitors have not been effective in treating EGFR-positive glioblastoma patients.The mechanism behind this type of primary resistance is not well understood.The aim of this study was to investigate gefitinib resistance in glioblastoma, and explore ways to circumvent this significant clinical problem.Methods: MTT method was used to test the cell viability after EGFR-positive glioblastoma cells were treated with indicated drugs;real-time quantitative PCR method was included to detect the TNFα mRNA levels in glioma tissues and cell lines.ELISA was introduced to measure the TNFα protein levels in cell culture supernatant of glioblastoma cells treated with gefitinib.Western blot was used to detect the activity change of intracellular kinases in drug-treated glioblastoma cells.Two mouse xenograft tumor models were carried out to evaluate the in vivo effects of a combination of EGFR and TNFα inhibitors.Results: We found that glioblastoma resistance to gefitinib may be mediated by an adaptive pro-survival TNFα-JNK-Axl signaling axis, and that high TNFα levels in the glioblastoma microenvironment may further intensify primary resistance.A combination of the TNFα-specific small-molecule inhibitor C87 and gefitinib significantly enhanced the sensitivity of glioblastoma cells to gefitinib in vitro and in vivo.Conclusions: Our findings provide a possible explanation for the primary resistance of glioblastoma to EGFR inhibitors and suggest that dual blockade of TNFα and EGFR may be a viable therapeutic strategy for the treatment of patients with chemotherapy-refractory advanced glioblastoma. | Li Ma Chunhua She Qian Shi Qiang Yin Xinxin Ji Yongrong Wang Yulong Fan Xinyao Kong Peng Li Zengfeng Sun Xiaohui Zhang Zhen Zhang Jian Wang Tong Wang Yuanfu Xu Wenliang Li | 2019 | Cancer Biology & Medicine2019，16，3： | 1 |
| 12 | Large transverse thermoelectric figure of merit in a topological Dirac semimetal显示文摘The Seebeck effect encounters a few fundamental constraints hindering its thermoelectric(TE)conversion efficiency.Most notably,there are the charge compensation of electrons and holes that diminishes this effect,and the Wiedemann-Franz(WF)law that makes independent optimization of the corresponding electrical and thermal conductivities impossible.Here,we demonstrate that in the topological Dirac semimetal Cd3As2 the Nernst effect,i.e.,the transverse counterpart of the Seebeck effect,can generate a large TE figure of merit zNT.At room temperature,zNT≈0.5 in a small field of 2 T and it significantly surmounts its longitudinal counterpart for any field.A large Nernst effect is generically expected in topological semimetals,benefiting from both the bipolar transport of compensated electrons and holes and their high mobilities.In this case,heat and charge transport are orthogonal,i.e.,not intertwined by the WF law anymore.More importantly,further optimization of zNT by tuning the Fermi level to the Dirac node can be anticipated due to not only the enhanced bipolar transport,but also the anomalous Nernst effect arising from a pronounced Berry curvature.A combination of the topologically trivial and nontrivial advantages promises to open a new avenue towards high-efficient transverse thermoelectricity. | JunSen Xiang SiLe Hu Meng Lyu WenLiang Zhu ChaoYang Ma ZiYu Chen Frank Steglich GenFu Chen PeiJie Sun | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，3： | 0 |
| 13 | Two-photon live imaging of direct glia-to-neuron conversion in the mouse cortex显示文摘Over the past decade,a growing number of studies have reported transcription factor-based in situ reprogramming that can directly conve rt endogenous glial cells into functional neurons as an alternative approach for n euro regeneration in the adult mammalian central ne rvous system.Howeve r,many questions remain regarding how a terminally differentiated glial cell can transform into a delicate neuron that forms part of the intricate brain circuitry.In addition,concerns have recently been raised around the absence of astrocyte-to-neuron conversion in astrocytic lineage-tra cing mice.In this study,we employed repetitive two-photon imaging to continuously capture the in situ astrocyte-to-neuron conversion process following ecto pic expression of the neural transcription factor NeuroD1 in both prolife rating reactive astrocytes and lineage-tra ced astrocytes in the mouse cortex.Time-lapse imaging over several wee ks revealed the ste p-by-step transition from a typical astrocyte with numero us short,tapered branches to a typical neuro n with a few long neurites and dynamic growth cones that actively explored the local environment.In addition,these lineage-converting cells were able to migrate ra dially or to ngentially to relocate to suitable positions.Furthermore,two-photon Ca2+imaging and patch-clamp recordings confirmed that the newly generated neuro ns exhibited synchronous calcium signals,repetitive action potentials,and spontaneous synaptic responses,suggesting that they had made functional synaptic connections within local neural circuits.In conclusion,we directly visualized the step-by-step lineage conversion process from astrocytes to functional neurons in vivo and unambiguously demonstrated that adult mammalian brains are highly plastic with respect to their potential for neuro regeneration and neural circuit reconstruction. | Zongqin Xiang Shu He Rongjie Chen Shanggong Liu Minhui Liu Liang Xu Jiajun Zheng Zhouquan Jiang Long Ma Ying Sun Yongpeng Qin Yi Chen Wen Li Xiangyu Wang Gong Chen Wenliang Lei | 2024 | Neural Regeneration Research2024，19，8： | 0 |
| 14 | Determination of Double Beta Decay Half-Life of 136Xe with the PandaX-4T Natural Xenon Detector显示文摘Precise measurement of two-neutrino double beta decay(DBD)half-life is an important step for the searches of Majorana neutrinos with neutrinoless double beta decay.We report the measurement of DBD half-life of 136xe using the Pandax-4T dual-phase Time Projection Chamber(TPC)with 3.7-tonne natural xenon and the first 94.9-day physics data release. | Lin Si Zhaokan Cheng Abdusalam Abdukerim Zihao Bo Wei Chen Xun Chen Yunhua Chen Chen Cheng Yunshan Cheng Xiangyi Cui Yingjie Fan Deqing Fang Changbo Fu Mengting Fu Lisheng Geng Karl Giboni Linhui Gu Xuyuan Guo Ke Han Changda He Jinrong He Di Huang Yanlin Huang Zhou Huang Ruquan Hou Xiangdong Ji Yonglin Ju Chenxiang Li Jiafu Li Mingchuan Li Shu Li Shuaijie Li Qing Lin Jianglai Liu Xiaoying Lu Lingyin Luo Yunyang Luo Wenbo Ma Yugang Ma Yujun Mao Yue Meng Nasir Shaheed Xiaofeng Shang Xuyang Ning Ningchun Qi Zhicheng Qian Xiangxiang Ren Changsong Shang Guofang Shen Wenliang Sun Andi Tan Yi Tao Anqing Wang Meng Wang Qiuhong Wang Shaobo Wang Siguang Wang Wei Wang Xiuli Wang Zhou Wang Yuehuan Wei Mengmeng Wu Weihao Wu Jingkai Xia Mengjiao Xiao Xiang Xiao Pengwei Xie Binbin Yan Xiyu Yan Yong Yang Chunxu Yu Jumin Yuan Ying Yuan Zhe Yuan Dan Zhang Minzhen Zhang Peng Zhang Shibo Zhang Shu Zhang Tao Zhang Li Zhao Qibin Zheng Jifang Zhou Ning Zhou Xiaopeng Zhou Yong Zhou | 2023 | Research2023，，2： | 0 |
| 15 | Exploring marine endosymbiosis systems with omics techniques显示文摘Endosymbiosis is the phenomenon where one organism lives inside another,usually in a mutualistic way.In this system,the hosts provide shelter and nutrients to the endosymbionts,who could affect the hosts in a physiological(Sommer and B?ckhed,2013),behavioral(Ezenwa et al.,2012),and evolutionary(Perlmutter and Bordenstein,2020)way. | Yisi Hu Shuyan Sun Huizhong Fan Wenliang Zhou Fuwen Wei | 2021 | Science China(Life Sciences)2021，64，6： | 0 |
| 16 | Flavor changes in Lentinus Edodes enzymatic hydrolysate maillard reaction products with different sugars by gas chromatography‐ion mobility spectrometry显示文摘The characteristic flavor of the enzymatic hydrolysate of Lentinus edodes,which was involved in the Maillard reaction by xylose,fructose,glucose,sucrose,mannose,maltose,vitamin C(VC)and L-arabinose,was determined and analyzed by gas chromatography-ion mobility spectroscopy(GC-IMS).The characteristic flavor fingerprints of Maillard reaction products(MRPs)of L.edodes enzymatic hydrolysate were constructed.The differences in the characteristic flavors of Maillard reaction with different reducing sugars and VC were compared.The main characteristic flavor,characteristic peak,characteristic marker substance and content were determined,a principal component analysis(PCA)of volatile organic compounds(VOCs)was carried out.The results showed that there were 42 kinds of monomers and some dimers of volatile compounds in the samples including 17 aldehydes,5 alcohols,7 ketones,2 esters,2 acids,7 other compounds and 2 ethers.The volatile VOCs of the sample with added sucrose,VC and L-arabinose were significantly higher than those of the enzymatic hydrolysate of L.edodes.After the Maillard reaction,the flavor of the hydrolysate was significantly improved,and the main components changed significantly. | Wenjia Cui Peiji Liu Houli Liu Yifei Sun Wenliang Wang | 2023 | Journal of Future Foods2023，3，1： | 0 |
| 17 | Chassis tra fficability simulation and experiment of a LY1352JP forest tracked vehicle显示文摘Based on the analysis of complex terrains and current forest transportation equipment,a forest tracked vehicle prototype LY1352 JP was developed.The road model and the virtual prototype of the chassis were constructed using dynamic simulation software RecurDyn.The optimal tension of the vehicle as well as its capabilities for crossing trenches,climbing vertical walls,uphill and downhill slopes were simulated.The simulation results showed that the optimum tension force of the chassis of the vehicle was 63 kN(kilonewton),accounting for 45%of the total vehicle weight.The maximum trench crossing width and vertical obstacle climbing height were 1.35 m and 0.45 m,respectively.The maximum uphill and downhill angles were 50°and 45°,respectively.Tests on the prototype capacity for crossing trenches,and uphill and downhill driving were carried out.The test results were in agreement with the simulation results.A cross-country performance of a fire truck based on the tracked vehicle chassis was conducted in an old-growth forest.Tests verified that the vehicle has a strong forest trafficability performance and can meet the needs for forest transportation. | Shufa Sun Jinfeng Wu Chunlong Ren Hualin Tang Jianwei Chen Wenliang Ma Jiangwei Chu | 2021 | Journal of Forestry Research2021，32，3： | 0 |
| 18 | Multi-dimensional size effects and representative elements for nonpersistent fractured rock masses: A perspective of geometric parameter distribution显示文摘This study takes a fractured rock mass in the Datengxia Hydropower Station,China as an example to analyze the size effects and determine the representative elementary sizes.A novel method considering geometric parameter distributions is proposed in this work.The proposed method can quickly and simply determine the size effects and representative elementary sizes.Specifically,geometric parameter distributions,including fracture frequency,size and orientation,are generated on the basis of the Bernoulli trial and Monte Carlo simulation.The distributions are assessed using the coefficient of variation(CV),and the acceptable variations for CV(5%,10%and 20%)are used to determine representative elementary sizes.Generally,the representative element of rock masses is the representative elementary volume(REV).The present study extends the representative element to other dimensions,i.e.representative elementary length(REL)and representative elementary area(REA)for one and two dimensions,respectively.REL and REA are useful in studying the size effects of one-(1D)and twodimensional(2D)characteristics of rock masses.The relationships among multi-dimensional representative elementary sizes are established.The representative elementary sizes reduce with the increase in the dimensions,and REA and REV can be deduced by REL.Therefore,the proposed method can quickly and simply determine REL and further estimate REA and REV,which considerably improves the efficiency of rock mass analysis. | Jia Wang Wen Zhang Chun Tan Zhenbang Nie Wenliang Ma Donghui Chen Qi Sun | 2023 | Journal of Rock Mechanics and Geotechnical Engineering2023，15，9： | 0 |
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