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| 1 | Genome analysis of Taraxacum kok-saghyz Rodin provides new insights into rubber biosynthesis显示文摘The Russian dandelion Taraxacum kok-saghyz Rodin(TKS), a member of the Composite family and a potential alternative source of natural rubber(NR) and inulin, is an ideal model system for studying rubber biosynthesis. Here we present the draft genome of TKS, the first assembled NR-producing weed plant. The draft TKS genome assembly has a length of 1.29 Gb, containing 46 731 predicted protein-coding genes and68.56% repeats, in which the LTR-RT elements predominantly contribute to the genome enlargement. We analyzed the heterozygous regions/genes, suggesting its possible involvement in inbreeding depression.Through comparative studies between rubber-producing and non-rubber-producing plants, we found that enzymes of the mevalonate(MVA) pathway and rubber elongation might be critical for rubber biosynthesis, and several key isoforms have been isolated and shown to be predominantly expressed in the latex, indicating their crucial functions in rubber biosynthesis. Moreover, for two important families in rubber elongation, the CPT/CPTL and REF/SRPP families, diverse evolutionary tracks have been revealed. These results provide valuable resources and new insights into the mechanism of NR biosynthesis,and facilitate the development of alternative NR-producing crops. | Tao Lin Xia Xu Jue Ruan Shizhong Liu Shigang Wu Xiujuan Shao Xiaobo Wang Lin Gan Bi Qin Yushuang Yang Zhukuan Cheng Suhua Yang Zhonghua Zhang Guosheng Xiong Sanwen Huang Hong Yu Jiayang Li | 2018 | National Science Review2018，5，1： | 22 |
| 2 | Corrigendum to'Preparation of high-purity straight silicon nanowires by molten salt electrolysis'[Journal of Energy Chemistry 40(2020)171-179]显示文摘 | Jie Zhang Sheng Fang Xiaopeng Qi Zhanglong Yu Zhaohui Wu Juanyu Yang Shigang Lu | 2020 | Journal of Energy Chemistry2020，29，1： | 5 |
| 3 | Understanding divergent domestication traits from the whole-genome sequencing of swamp-and river-buffalo populations显示文摘Domesticated buffaloes have been integral to rice-paddy agro-ecosystems formillennia,yet relatively little is known about the buffalo genomics.Here,we sequenced and assembled reference genomes for both swamp and river buffaloes and we re-sequenced 230 individuals(132 swamp buffaloes and 98 river buffaloes)sampled from across Asia and Europe.Beyond the many actionable insights that our study revealed about the domestication,basic physiology and breeding of buffalo,we made the striking discovery that the divergent domestication traits between swamp and river buffaloes can be explained with recent selections of genes on social behavior,digestion metabolism,strengths and milk production. | Xier Luo Yu Zhou Bing Zhang Yi Zhang Xiaobo Wang Tong Feng Zhipeng Li Kuiqing Cui Zhiqiang Wang Chan Luo Hui Li Yanfei Deng Fenghua Lu Jianlin Han Yongwang Miao Huaming Mao Xiaoyan Yi Cheng Ai Shigang Wu Alun Li Zhichao Wu Zijun Zhuo Do Da Giang Bikash Mitra Mohammad Farhad Vahidi Shahid Mansoor Sahar Ahmed Al-Bayatti Eka Meutia Sari Neena Amatya Gorkhali Sigit Prastowo Laiba Shafique Guoyou Ye Qian Qian Baoshan Chen Deshun Shi Jue Ruan Qingyou Liu | 2020 | National Science Review2020，7，3： | 3 |
| 4 | STUDY ON IMAGE EDGE PROPERTY LOCATION BASED ON FRACTAL THEORY显示文摘A novel approach of printed circuit board(PCB)image locating is presented Based on the rectangle mark image edge of PCB,the featur es is used to describe the image edge and the fractal properby of image edge is analyzed It is proved that the rectangle mark image edge of PCB has some fractal features A method of deleting unordinary curve noise and compensating the length of the fractal curve is put forward,which can get the fractal dimension value from one complex edge fractal property curve The relation between the dim ension of the fractal curve and the turning angle of image can be acquired from an equation,as a result,the angle value of the PCB image is got exactly A real image edge analysis result confirms that the method based on the fractal theory is a new powerful tool for angle locating on PCB and related image area. | Wang Hong, Wang Shigang, Xu Wei, Yu Xinrui (Institute of Robots,Shanghai Jiaotong University) | 2001 | Chinese Journal of Mechanical Engineering2001，14，4： | 2 |
| 5 | Modelingthe static vertical force of the core-type permanent-magnet planar motor显示文摘 | Cao Jiayong Wang Shigang Zhu Yu | 2008 | IEEE Transactions onMagnetics2008，44，12： | 1 |
| 6 | Flexible robot beam element for the manipulators with joint and link flexibility显示文摘 | Yue Shigang Yu Yueqing Bai Shixian | 1997 | Mechanism and Machine theory1997，32，2： | 1 |
| 7 | Flexible Rotor Beam Element for the Manipulators with Joint and L ink Flexibility显示文摘 | Yue Shigang Yu Yueqing Bai Shixian | 1997 | Mech Mach Theory1997，，： | 1 |
| 8 | The First High-quality Reference Genome of Sika Deer Provides Insights into High-tannin Adaptation显示文摘Sika deer are known to prefer oak leaves,which are rich in tannins and toxic to most mammals;however,the genetic mechanisms underlying their unique ability to adapt to living in the jungle are still unclear.In identifying the mechanism responsible for the tolerance of a highly toxic diet,we have made a major advancement by explaining the genome of sika deer.We generated the first high-quality,chromosome-level genome assembly of sika deer and measured the correlation between tannin intake and RNA expression in 15 tissues through 180 experiments.Comparative genome analyses showed that the UGT and CYP gene families are functionally involved in the adaptation of sika deer to high-tannin food,especially the expansion of the UGT family 2 subfamily B of UGT genes.The first chromosome-level assembly and genetic characterization of the tolerance to a highly toxic diet suggest that the sika deer genome may serve as an essential resource for understanding evolutionary events and tannin adaptation.Our study provides a paradigm of comparative expressive genomics that can be applied to the study of unique biological features in non-model animals. | Xiumei Xing Cheng Ai Tianjiao Wang Yang Li Huitao Liu Pengfei Hu Guiwu Wang Huamiao Liu Hongliang Wang Ranran Zhang Junjun Zheng Xiaobo Wang Lei Wang Yuxiao Chang Qian Qian Jinghua Yu Lixin Tang Shigang Wu Xiujuan Shao Alun Li Peng Cui Wei Zhan Sheng Zhao Zhichao Wu Xiqun Shao Yimeng Dong Min Rong Yihong Tan Xuezhe Cui Shuzhuo Chang Xingchao Song Tongao Yang Limin Sun Yan Ju Pei Zhao Huanhuan Fan Ying Liu Xinhui Wang Wanyun Yang Min Yang Tao Wei Shanshan Song Jiaping Xu Zhigang Yue Qiqi Liang Chunyi Li Jue Ruan Fuhe Yang | 2023 | Genomics, Proteomics & Bioinformatics2023，21，1： | 1 |
| 9 | Flexible rotor beam element for the manipulators with joint and link flexiblity显示文摘 | Yue Shigang Yu Yueqing Bai Shixian | 1997 | Mechanism and Machine Theory1997，32，2： | 1 |
| 10 | Efficient oxygen electrocatalysts with highly-exposed Co-N4 active sites on N-doped graphene-like hierarchically porous carbon nanosheets enhancing the performance of rechargeable Zn-air batteries显示文摘Designing bifunctional oxygen electrocatalysts with high activity,lasting stability,and low-cost for rechargeable zinc-air batteries(RZABs)is a tough challenge.Herein,an advanced electrocatalyst is prepared by anchoring atomically dispersed Co atoms on Ndoped graphene-like hierarchically porous carbon nanosheets(SA-Co-N4-GCs)and thereby forming Co-N4-C architecture.Its unique structure with excellent conductivity,large surface area,and three dimensional(3D)interconnected hierarchically porous architecture exposes not only more Co-N4 active sites to accelerate the kinetics of both oxygen reduction reaction(ORR)and oxygen evolution reaction(OER),but also provides an efficient charge/mass transport environment to reduce diffusion barrier.Consequently,SA-Co-N4-GCs exhibits excellent ORR/OER bifunctional activities and durability,surpassing noble-metal catalysts.Liquid RZABs using SA-Co-N4-GCs cathodes display a high open-circuit voltage of 1.51 V,a remarkable power density of 149.3 mW·cm−2,as well as excellent stability and rechargeability with faint increase in polarization even at a large depth of charge–discharge cycle with 16 h per cycle over an entire 600 h long-term test.Moreover,flexible quasi-solid-state RZABs with SA-Co-N4-GCs cathodes also deliver a considerable power density of 124.5 mW·cm−2,which is even higher than that of liquid batteries using noble-metal catalysts.This work has thrown new insight into development of high-performance and low-cost electrocatalysts for energy conversion and storage. | Nengfei Yu Hui Chen Jingbiao Kuang Kailin Bao Wei Yan Jilei Ye Zhongtang Yang Qinghong Huang Yuping Wu Shigang Sun | 2022 | Nano Research2022，15，8： | 0 |
| 11 | Preparation of high-purity straight silicon nanowires by molten salt electrolysis显示文摘Silicon nanowires of high purity and regular morphology are of prime importance to ensure high specific capacities of lithium-ion batteries and reproducible electrode assembly process.Using nickel formate as a metal catalyst precursor,straight silicon nanowires(65–150 nm in diameter)were directly prepared by electrolysis from the Ni/SiO2 porous pellets with 0.8 wt%nickel content in molten CaCl2 at 900℃.Benefiting from their straight appearance and high purity,the silicon nanowires therefore offered an initial coulombic efficiency of 90.53% and specific capacity of 3377 m Ah/g.In addition,the silicon nanowire/carbon composite exhibited excellent cycle performance,retaining 90.38%of the initial capacity after 100 cycles.Whilst further study on the charge storage performance is still ongoing,these preliminary results demonstrate that nickel formate is an efficient and effective metal catalyst precursor for catalytic preparation of high purity straight silicon nanowires via the molten salt electrolysis,which is suitable for large-scale production. | Jie Zhang Sheng Fang Xiaopeng Qi Zhanglong Yu Zhaohui Wu Juanyu Yang Shigang Lu | 2020 | Journal of Energy Chemistry2020，29，1： | 0 |
| 12 | COVID-19 pharmacological research trends:a bibliometric analysis显示文摘Background:The coronavirus disease 2019(COVID-19)pandemic is ravaging the world.Many therapies have been explored to treat COVID-19.This report aimed to assess the global research trends for the development of COVID-19 therapies.Methods:We searched the relevant articles on COVID-19 therapies published from January 1,2020,to May 25,2022,in the Web of Science Core Collection Database(WOSCC).VOSviewer 1.6.18 software was used to assess data on the countries,institutions,authors,collaborations,keywords,and journals that were most implicated in COVID-19 pharmacological research.The latest research and changing trends in COVID-19-relevant pharmacological research were analyzed.Results:After manually eliminating articles that do not meet the requirements,a total of 5,289 studies authored by 32,932 researchers were eventually included in the analyses,which comprised 95 randomized controlled trials.3,044(57.6%)studies were published in 2021.The USA conducted the greatest number of studies,followed by China and India.The primary USA collaborators were China and England.The topics covered in the publications included:the general characteristics,the impact on pharmacists’work,the pharmacological research,broad-spectrum antiviral drug therapy and research,and promising targets or preventive measures,such as vaccine.The temporal diagram revealed that the current research hotspots focused on the vaccine,molecular docking,Mpro,and drug delivery keywords.Conclusion:Comprehensive bibliometric analysis could aid the rapid identification of the principal research topics,potential collaborators,and the direction of future research.Pharmacological research is critical for the development of therapeutic and preventive COVID-19-associated measures.This study may therefore provide valuable information for eradicating COVID-19. | Yanyan Shi Yahan Song Zhijun Guo Wei Yu Huiling Zheng Shigang Ding Siyan Zhan | 2023 | Intelligent Medicine2023，3，1： | 0 |
| 13 | PROPERTIES AND IMMUNOACTIVITY OF MODIFIED IMMUNOGLOBULING BY METHOXYPOLYETHYLENE GLYCOL显示文摘Methoxypolyethylene glycols of 5000 dalton(PEG) have been attached covalentlyto human serum immunoglobulin G using 2,4,6-trichloro-s-triazine as coupling agent. The modi-fied IgG showed substantial changes in properties as compared with the unmodified IgG. The mod-ified IgG showed increase in molecular weight, increase of tolerance to temperature and PH, de-crease of immunogenicity and retaining most of its immunoactivity. The CD spectra showed no ap-parent changes in its main structure. IgG with 50. 3% of its amino groups modified by PEG had its immunogenicity completely re-moved ,while maintaining 53.7% of its immunoactivity. | Shi Jianying Tong Mingrong Chen Jiatong shen Shigang Yu Yaoting,Institute for Molecular Biology Nankai University. Tianjin. P. R. China | 1993 | Chinese Journal of Biomedical Engineering(English Edition)1993，2，1： | 0 |
| 14 | Attacks and defences on intelligent connected vehicles:a survey显示文摘Intelligent vehicles are advancing at a fast speed with the improvement of automation and connectivity,which opens up new possibilities for different cyber-attacks,including in-vehicle attacks(e.g.,hijacking attacks)and vehicle-to-everything communicationattacks(e.g.,data theft).These problems are becoming increasingly serious with the development of 4G LTE and 5G communication technologies.Although many efforts are made to improve the resilience to cyber attacks,there are still many unsolved challenges.This paper first identifies some major security attacks on intelligent connected vehicles.Then,we investigate and summarize the available defences against these attacks and classify them into four categories:cryptography,network security,software vulnerability detection,and malware detection.Remaining challenges and future directions for preventing attacks on intelligent vehicle systems have been discussed as well. | Mahdi Dibaei Xi Zheng Kun Jiang Robert Abbas Shigang Liu Yuexin Zhang Yang Xiang Shui Yu | 2020 | Digital Communications and Networks2020，6，4： | 0 |
| 15 | Construction risks of Huaying mount tunnel and countermeasures显示文摘 | Haibo YAO Feng GAO Shigang YU Wei DANG | 2017 | Frontiers of Structural and Civil Engineering2017，11，3： | 0 |
| 16 | The piRNA pathway is required for nucleopolyhedrovirus replication in Lepidoptera显示文摘The Piwi-interacting RNA(piRNA)pathway has been shown to be involved in the antiviral defense against RNA viruses,especially in mosquitoes,but its universality has been questioned.Here,we used the Bombyx mori nucleopolyhedrovirus(BmNPV)-infected silkworm as a model to explore the effects of the key factors of piRNA pathway,BmAgo3 and Siwi,on replication of a large DNA virus(belonging to the family of Baculoviridae).We demonstrated that BmAgo3 and Siwi could promote the replication of BmNPV through both overexpression and knockdown experiments in BmN cell lines and silkworm larvae.In addition,we also studied the effect of PIWI-class genes on Autographa californica nucleopolyhedrovirus(AcMNPV)replication in the Spodoptera frugiperda cell line Sf9.By knocking down the expression of PIWI-class genes in Sf9,we found that Piwi-like-1 and Piwi-like-2-3 could inhibit AcMNPV replication,while Piwi-like-4-5 promoted virus replication.Our study provides compelling evidence that the piRNA pathway affects host infection by exogenous viruses in Lepidoptera.Also,our results reflect the diversity of the roles of PIWI-class genes in virus infection of the host across species.This study is the first to explore the interaction of PIWI-class proteins with DNA viruses,providing new insights into the functional roles of the piRNA pathway. | Junming Xia Shigang Fei Hongyun Wu Yifan Yang Wensheng Yu Mengmeng Zhang Yiyao Guo Luc Swevers Jingchen Sun Min Feng | 2023 | Insect Science2023，30，5： | 0 |
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