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| 1 | 帕金森病血压管理专家共识显示文摘近年来,随着临床实践及研究的进展,帕金森病(Parkinson’s disease, PD)已经从局限于中枢神经系统的疾病范畴扩展为可累及全身多个系统的多系统疾病,其中以直立性低血压(orthostatic hypotension, OH)为代表的血压异常,作为一种常见的非运动症状(non-motor symptoms, NMSs),可发生在PD的整个病程任一时间点。 | 陈施吾 窦荣花 王玉凯 王含 王晓平 陈先文 陈玲 王训 屈洪党 陈生弟 Susan Fox 李燕 王刚 | 2020 | 内科理论与实践2020,15,3: | 9 |
| 2 | Tight junction disruption: Helicobacter pylori and dysregulation of the gastric mucosal barrier显示文摘Long-term chronic infection with Helicobacter pylori(H. pylori) is a risk factor for gastric cancer development. In the multi-step process that leads to gastric cancer,tight junction dysfunction is thought to occur and serve as a risk factor by permitting the permeation of luminal contents across an otherwise tight mucosa. Mechanisms that regulate tight junction function and structure in the normal stomach,or dysfunction in the infected stomach,however,are largely unknown. Although conventional tight junction components are expressed in gastric epithelial cells,claudins regulate paracellular permeability and are likely the target of inflammation or H. pylori itself. There are 27 different claudin molecules,each with unique properties that render the mucosa an intact barrier that is permselective in a way that is consistent with cell physiology. Understanding the architecture of tight junctions in the normal stomach and then changes that occur during infection is important but challenging,because most of the reports that catalog claudin expression in gastric cancer pathogenesis are contradictory. Furthermore,the role of H. pylori virulence factors,such as cytotoxin-associated gene A and vacoulating cytotoxin,in regulating tight junction dysfunction during infection is inconsistent in different gastric cell lines and in vivo,likely because non-gastric epithelial cell cultures were initially used to unravel the details of their effects on the stomach. Hampering further study,as well,is the relative lack of cultured cell models that have tight junction claudins that are consistent with native tissues. This summary will review the current state of knowledge about gastric tight junctions,normally and in H. pylori infection,and make predictions about the consequences of claudin reorganization during H. pylori infection. | Tyler J Caron Kathleen E Scott James G Fox Susan J Hagen | 2015 | World Journal of Gastroenterology2015,21,40: | 7 |
| 3 | Heart Disease and Stroke Statistics—2013 Update: A Report From the American Heart Association显示文摘 | Alan S. Go Dariush Mozaffarian Véronique L. Roger Emelia J. Benjamin Jarett D. Berry William B. Borden Dawn M. Bravata Shifan Dai Earl S. Ford Caroline S. Fox Sheila Franco Heather J. Fullerton Cathleen Gillespie Susan M. Hailpern John A. Heit Virginia J. | 2013 | Circulation2013,,1: | 5 |
| 4 | Heart Disease and Stroke Statistics—2011 Update: A Report From the American Heart Association显示文摘 | Véronique L. Roger Alan S. Go Donald M. Lloyd-Jones Robert J. Adams Jarett D. Berry Todd M. Brown Mercedes R. Carnethon Shifan Dai Giovanni de Simone Earl S. Ford Caroline S. Fox Heather J. Fullerton Cathleen Gillespie Kurt J. Greenlund Susan M. Hailpern | 2011 | Circulation2011,,4: | 4 |
| 5 | Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study显示文摘 | Shamir R Mehta Salim Yusuf Ron JG Peters Michel E Bertrand Basil S Lewis Madhu K Natarajan Klas Malmberg Hans-Jürgen Rupprecht Feng Zhao Susan Chrolavicius Ingrid Copland Keith AA Fox | 2001 | The Lancet . 2001 (9281)2001,,9281: | 4 |
| 6 | 帕金森病血压管理专家共识显示文摘近年来,随着临床实践及研究的进展,帕金森病(Parkinson disease, PD)已经从局限于中枢神经系统的疾病范畴扩展为可累及全身多个系统的多系统疾病,其中以直立性低血压(orthostatic hypotension, OH)为代表的血压异常,作为一种常见的非运动症状(non-motor symptom, NMS),可发生在PD病程中的任一时间点。PD的血压异常既与患者的自主神经功能异常有关,也与抗PD药物应用的不良反应密切相关,是严重影响患者生活质量(quality of life, QoL)的关键因素。 | 陈施吾 窦荣花 王玉凯 王含 王晓平 陈先文 陈玲 王训 屈洪党 陈生弟 Susan Fox 李燕 王刚 | 2020 | 诊断学理论与实践2020,19,5: | 4 |
| 7 | Executive Summary: Heart Disease and Stroke Statistics—2013 Update: A Report From the American Heart Association显示文摘 | Alan S. Go Dariush Mozaffarian Véronique L. Roger Emelia J. Benjamin Jarett D. Berry William B. Borden Dawn M. Bravata Shifan Dai Earl S. Ford Caroline S. Fox Sheila Franco Heather J. Fullerton Cathleen Gillespie Susan M. Hailpern John A. Heit Virginia J. | 2013 | Circulation2013,,1: | 4 |
| 8 | Executive Summary: Heart Disease and Stroke Statistics—2012 Update: A Report From the American Heart Association显示文摘 | Véronique L. Roger Alan S. Go Donald M. Lloyd-Jones Emelia J. Benjamin Jarett D. Berry William B. Borden Dawn M. Bravata Shifan Dai Earl S. Ford Caroline S. Fox Heather J. Fullerton Cathleen Gillespie Susan M. Hailpern John A. Heit Virginia J. Howard Bret | 2012 | Circulation2012,,1: | 2 |
| 9 | Heart Disease and Stroke Statistics—2013 Update: A Report From the American Heart Association显示文摘 | Alan S. Go Dariush Mozaffarian Véronique L. Roger Emelia J. Benjamin Jarett D. Berry William B. Borden Dawn M. Bravata Shifan Dai Earl S. Ford Caroline S. Fox Sheila Franco Heather J. Fullerton Cathleen Gillespie Susan M. Hailpern John A. Heit Virginia J. | 2013 | Circulation2013,,1: | 1 |
| 10 | Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans显示文摘 | Rhee Eugene P Cheng Susan Larson Martin G Walford Geoffrey A Lewis Gregory D McCabe Elizabeth Yang Elaine Farrell Laurie Fox Caroline S O’Donnell Christopher J Carr Steven A Vasan Ramachandran S Florez Jose C Clish Clary B Wang Thomas J Ger | 2011 | Journal of Clinical Investigation2011,,4: | 1 |
| 11 | Mutations in filamin 1 Prevent Migration of Cerebral Cortical Neurons in Human Periventricular Heterotopia显示文摘 | Jeremy W Fox Edward D Lamperti Yaman Z Ek?io?lu Susan E Hong Yuanyi Feng Donna A Graham Ingrid E Scheffer William B Dobyns Betsy A Hirsch Rodney A Radtke Samuel F Berkovic Peter R Huttenlocher Christopher A Walsh | 1998 | Neuron1998,,6: | 1 |
| 12 | Evaluating implicit measures to improve web search显示文摘 | Steve Fox Kuldeep Karnawat Mark Mydland Susan Dumais Thomas White | 2005 | ACM Transactions on Information Systems (TOIS)2005,,2: | 1 |
| 13 | The Female as Metaphor in William Blake' s Poetry 显示文摘 | Fox Susan | 1977 | Critical Inquiry1977,3,3: | 1 |
| 14 | 5-HT2 receptor antagonists enhance the behavioral response to dopamine D1 receptor agonists in the 6-hydroxy dopamine-lesioned rat显示文摘 | Susan H Fox Jonathan M Brotchie | 2000 | European Journal of Pharmacology2000,398,: | 1 |
| 15 | RON RECEPTOR TYROSINE KINASE NEGATIVELY REGULATES TNFα PRODUCTION IN ALVEOLAR MACROPHAGES BY INHIBITING NF-κB ACTIVITY AND ADAM17 PRODUCTION显示文摘 | Nikolaos M. Nikolaidis Jerilyn K. Gray Devikala Gurusamy William Fox William D. Stuart Nathan Huber Susan E. Waltz | 2010 | Shock2010,,2: | 1 |
| 16 | Heart Disease and Stroke Statistics—2013 Update: A Report From the American Heart Association显示文摘 | Alan S. Go Dariush Mozaffarian Véronique L. Roger Emelia J. Benjamin Jarett D. Berry William B. Borden Dawn M. Bravata Shifan Dai Earl S. Ford Caroline S. Fox Sheila Franco Heather J. Fullerton Cathleen Gillespie Susan M. Hailpern John A. Heit Virginia J. | 2013 | Circulation2013,,1: | 1 |
| 17 | Heart Disease and Stroke Statistics—2013 Update: A Report From the American Heart Association显示文摘 | Alan S. Go Dariush Mozaffarian Véronique L. Roger Emelia J. Benjamin Jarett D. Berry William B. Borden Dawn M. Bravata Shifan Dai Earl S. Ford Caroline S. Fox Sheila Franco Heather J. Fullerton Cathleen Gillespie Susan M. Hailpern John A. Heit Virginia J. | 2013 | Circulation2013,,1: | 1 |
| 18 | Pharmacological characterization of MK-6096 – A dual orexin receptor antagonist for insomnia显示文摘 | Christopher J. Winrow Anthony L. Gotter Christopher D. Cox Pamela L. Tannenbaum Susan L. Garson Scott M. Doran Michael J. Breslin John D. Schreier Steven V. Fox Charles M. Harrell Joanne Stevens Duane R. Reiss Donghui Cui Paul J. Coleman John J. Renger | 2011 | Neuropharmacology2011,,: | 1 |
| 19 | HER‐2 pulsed dendritic cell vaccine can eliminate HER‐2 expression and impact ductal carcinoma in situ显示文摘 | Anupama Sharma Ursula Koldovsky Shuwen Xu Rosemarie Mick Robert Roses Elizabeth Fitzpatrick Susan Weinstein Harvey Nisenbaum Bruce L. Levine Kevin Fox Paul Zhang Gary Koski Brian J. Czerniecki | 2012 | Cancer2012,,: | 1 |
| 20 | Prehospital triage of acute myocardial infarction: wireless transmission of electrocardiograms to the on-call cardiologist via a handheld computer显示文摘 | Paul T. Campbell Janet Patterson Deedee Cromer Karen Wall George L. Adams Alfred Albano Craig Corey Paula Fox Jim Gardner Barry Hawthorne Jonathan Lipton Maria Sejersten Alan Thompson Amanda Thompson Susan Wilfong Charles Maynard Galen Wagner | 2005 | Journal of Electrocardiology2005,,4: | 1 |