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| 1 | Shear wave velocity is a useful marker for managing nonalcoholic steatohepatitis显示文摘AIM:To investigate whether a noninvasive measurement of tissue strain has a potential usefulness for management of nonalcoholic steatohepatitis(NASH).METHODS:In total 26 patients,23 NASHs and 3 normal controls were enrolled in this study.NASH was staged based on Brunt criterion.At a region of interest(ROI),a shear wave was evoked by implementing an acoustic radiation force impulse(ARFI),and the propagation velocity was quantif ied.RESULTS:Shear wave velocity(SWV) could be reproducibly quantified at all ROIs in all subjects except for 4 NASH cases,in which a reliable SWV value was not calculated at several ROIs.An average SWV of 1.34 ± 0.26 m/s in fibrous stage 0-1 was significantly slower than 2.20 ± 0.74 m/s and 2.90 ± 1.01 m/s in stages 3 and 4,respectively,but was not significantly different from 1.79 ± 0.78 m/s in stage 2.When a cutoff value was set at 1.47 m/s,receiver operating characteristic analysis showed significance to dissociate stages 3 and 4 from stage 0-1(P=0.0092) with sensitivity,specificity and area under curve of 100%,75% and 94.2%,respectively.In addition,the correlation between SWV and hyaluronic acid was significant(P<0.0001),while a tendency toward negative correlation was observed with serum albumin(P=0.053).CONCLUSION:The clinical implementation of ARFI provides noninvasive repeated evaluations of liver stiffness at an arbitrary position,which has the potential to shed new light on NASH management. | Akihiko Osaki Tomoyuki Kubota Takeshi Suda Masato Igarashi Keisuke Nagasaki Atsunori Tsuchiya Masahiko Yano Yasushi Tamura Masaaki Takamura Hirokazu Kawai Satoshi Yamagiwa Toru Kikuchi Minoru Nomoto Yutaka Aoyagi | 2010 | World Journal of Gastroenterology2010，16，23： | 30 |
| 2 | 精力的文学评论为执行 laparoscopic colorectal 外科采购原料显示文摘 Laparoscopic surgery for colorectal disease has become widespread as a minimally invasive treatment.This is important because the increasing availability of new devices allows us to perform procedures with a reduced length of surgery and decreased blood loss.We herein report the results of a literature review of energy sources for laparoscopic colorectal surgery,focused especially on 6 studies comparing ultrasonic coagulating shears(UCS) and other instruments.We also describe our laparoscopic dissection techniques using UCS for colorectal cancer.The short-term outcomes of surgeries using UCS and Ligasure for laparoscopiccolorectal surgery were superior to conventional electrosurgery.Some authors have reported that the length of surgery or blood loss when Ligasure was used for laparoscopic colorectal surgery is less than when UCS was used.On the other hand,a recent study demonstrated that there were no significant differences between the short-term outcomes of UCS and Ligasure for laparoscopic colorectal surgery.It is therefore suggested that the choice of technique used should be made according to the surgeon’s preference.We also describe our laparoscopic dissection techniques using UCS(Harmonic ACE) for colorectal cancer with regard to the retroperitoneum dissection,dissection technique,dissection technique around the feeding artery,and various other dissection techniques.We therefore review the outcomes of using various energy sources for laparoscopic colorectal surgery and describe our laparoscopic dissection techniques with UCS(Harmonic ACE) for colorectal cancer. | Tsukasa Hotta Katsunari Takifuji Shozo Yokoyama Kenji Matsuda Takashi Higashiguchi Toshiji Tominaga Yoshimasa Oku Takashi Watanabe Toru Nasu Tadamichi Hashimoto Koichi Tamura Junji Ieda Naoyuki Yamamoto Hiromitsu Iwamoto Hiroki Yamaue | 2012 | World Journal of Gastrointestinal Surgery2012，4，1： | 4 |
| 3 | Rescue of white egg 1 mutant by introduction of the wildtype Bombyx kynurenine 3-monooxygenase gene显示文摘在蚕,白鸡蛋 1 (w-1 ) 异种,被白眼睛和白鸡蛋描绘,在 Bombyx kynurenine 3-monooxygenase (KMO ) 是缺乏的活动。Toinvestigate w-1 异种显型是否被介绍野类型的 KMO 基因救,我们在细胞质的肌动朊基因倡导者(A3KMO ) 或本国的 KMO 基因倡导者(KKMO ) 的控制下面与野类型的 Bombyx KMO 基因构造了转基因的蚕。我们与 KKMO 构造与 A3KMO 和一根线创造了二根转基因的线。在这些线的成年人的眼睛是棕色的,并且转基因的女性生的鸡蛋也是棕色的。Reversetranscription 聚合酶链反应(RT-PCR ) 分析证明 A3KMO 蚕线在中间勇气的、胖身体表示了抄本,并且肾小体小管。KKMO 线仅仅在胖身体表示了抄本并且肾小体小管。在转基因的线的眼睛和卵色的紧张与 KMO 表示水平成正比。有趣地,有 A3KMO 构造的转基因的幼虫有轻褐幼虫的表皮,而是 KKMO 线不。这些结果显示野类型的 KMO 基因能作为标记基因被使用视觉上屏蔽转基因的蚕。 | GUO-XING QUAN ISAO KOBAYASHI KATSURA KOJIMA KEIRO UCHINO TOSHIO KANDA HIDEKI SEZUTSU TORU SHIMADA TOSHIKI TAMURA | 2007 | Insect Science2007，14，2： | 4 |
| 4 | Increased MicroRNA-1 and MicroRNA-133a Levels in Serum of Patients With Cardiovascular Disease Indicate Myocardial Damage显示文摘 | Yasuhide Kuwabara Koh Ono Takahiro Horie Hitoo Nishi Kazuya Nagao Minako Kinoshita Shin Watanabe Osamu Baba Yoji Kojima Satoshi Shizuta Masao Imai Toshihiro Tamura Toru Kita Takeshi Kimura | 2011 | Circulation: Cardiovascular Genetics2011，，： | 2 |
| 5 | Comparison of Perioperative and Long-term Outcomes of Total and Proximal Gastrectomy for Early Gastric Cancer: A Multi-institutional Retrospective Study显示文摘 | Toru Masuzawa Shuji Takiguchi Motohiro Hirao Hiroshi Imamura Yutaka Kimura Junya Fujita Isao Miyashiro Shigeyuki Tamura Masahiro Hiratsuka Kenji Kobayashi Yoshiyuki Fujiwara Masaki Mori Yuichiro Doki | 2014 | World Journal of Surgery2014，，5： | 2 |
| 6 | Removal of phosphate by aluminum oxide hydroxide显示文摘 | Seiki Tanada Mineaki Kabayama Naohito Kawasaki Toru Sakiyama Takeo Nakamura Mamiko Araki Takamichi Tamura | 2003 | Journal of Colloid And Interface Science2003，，1： | 2 |
| 7 | Cytotoxic T Lymphocytes Efficiently Recognize Human Colon Cancer Stem-Like Cells显示文摘 | Satoko Inoda Yoshihiko Hirohashi Toshihiko Torigoe Rena Morita Akari Takahashi Hiroko Asanuma Munehide Nakatsugawa Satoshi Nishizawa Yasuaki Tamura Tetsuhiro Tsuruma Takeshi Terui Toru Kondo Kunihiko Ishitani Tadashi Hasegawa Koichi Hirata Noriyuki Sato | 2011 | The American Journal of Pathology2011，，4： | 2 |
| 8 | 20-Hour preprocedural hydration is not superior to 5-hour preprocedural hydration in the prevention of contrast-induced increases in serum creatinine and cystatin C显示文摘 | Kumie Torigoe Akira Tamura Toru Watanabe Junichi Kadota | 2012 | International Journal of Cardiology2012，，： | 1 |
| 9 | Buccal administration of dexmedetomidine as a preanesthetic in children显示文摘 | Yoshio Sakurai Toru Obata Akio Odaka Katsuo Terui Masanori Tamura Hideki Miyao | 2010 | Journal of Anesthesia2010，，1： | 1 |
| 10 | The Feedback Phase of Type I Interferon Induction in Dendritic Cells Requires Interferon Regulatory Factor 8显示文摘 | Prafullakumar Tailor Tomohiko Tamura Hee Jeong Kong Toru Kubota Mayumi Kubota Paola Borghi Lucia Gabriele Keiko Ozato | 2007 | Immunity2007，，2： | 1 |
| 11 | Inhibitory effects of einnamaldehyde on 4 - (methylnitrosamino) - 1 - (3- pyridyl) - 1 - butanone - induced lung carciogenesis in rasH2 mice显示文摘 | Toshio Imai Kazuo Yasuhara Toru Tamura | 2002 | Cancer Lett2002，175，1： | 1 |
| 12 | Long-term comorbidity of diabetes mellitus is a risk factor for perineal wound complications after an abdominoperineal resection显示文摘 | Kenji Matsuda Tsukasa Hotta Katsunari Takifuji Shozo Yokoyama Takashi Higashiguchi Toshiji Tominaga Yoshimasa Oku Toru Nasu Koichi Tamura Hiroki Yamaue | 2009 | Langenbeck’s Archives of Surgery2009，，1： | 1 |
| 13 | Highly efficient electro-gene therapy of solid tumor by using an expression plasmid for the herpes simplex virus thymidine kinase gene显示文摘 | Tomoaki Goto Toru Nishi Takahiko Tamura | 2000 | Proc Natl Acad Sci U S A2000，97，1： | 1 |
| 14 | Percutaneous Transluminal Pulmonary Angioplasty for the Treatment of Chronic Thromboembolic Pulmonary Hypertension显示文摘 | Masaharu Kataoka Takumi Inami Kentaro Hayashida Nobuhiko Shimura Haruhisa Ishiguro Takayuki Abe Yuichi Tamura Motomi Ando Keiichi Fukuda Hideaki Yoshino Toru Satoh | 2012 | Circulation: Cardiovascular Interventions2012，，6： | 1 |
| 15 | Phylogenetic relationships between Sophophora and Lordiphosa , with proposition of a hypothesis on the vicariant divergences of tropical lineages between the Old and New Worlds in the family Drosophilidae显示文摘 | Jian-jun Gao Yao-guang Hu Masanori J. Toda Toru Katoh Koichiro Tamura | 2011 | Molecular Phylogenetics and Evolution2011，，1： | 1 |
| 16 | Association between coronary spastic angina pectoris and obstructive sleep apnea显示文摘 | Akira Tamura Yoshiyuki Kawano Shinichi Ando Toru Watanabe Junichi Kadota | 2010 | Journal of Cardiology2010，，2： | 1 |
| 17 | Effects of angiotensin II type 1 receptor blocker on blood pressure variability and cardiovascular remodeling in hypertensive patients on chronic peritoneal dialysis显示文摘 | Atsu- ichiro Shigenaga Kouiehi Tamura Toru Dejima | 2009 | Nephron Clin Pract2009，112，1： | 1 |
| 18 | Repeated dose (28 days) oral toxicity study of flutamide in rats, based on the draft protocol for the `Enhanced OECD Test Guideline 407’ for screening for endocrine-disrupting chemicals显示文摘 | Kazuhiro Toyoda Makoto Shibutani Toru Tamura Takatoshi Koujitani Chikako Uneyama Masao Hirose | 2000 | Archives of Toxicology2000，，3： | 1 |
| 19 | Prognostic impact and initial recurrence site of lymphovascular and visceral pleural invasion in surgically resected stage I non-small-cell lung carcinoma显示文摘 | Naoki Yanagawa Satoshi Shiono Masami Abiko Shin-ya Ogata Toru Sato Gen Tamura | 2013 | European Journal of Cardio-Thoracic Surgery2013，，3： | 1 |
| 20 | Prognostic Impact of Surgical Margin Width in Hepatectomy for Colorectal Liver Metastasis显示文摘As for resection for colorectal liver metastasis (CRLM), secur-ing an adequate surgical margin is important for achieving a better prognosis. However, it is often difficult to achieve ade-quate margins for the resection of CRLM. So the current sur-vival impact of sub-centi/millimeter surgical margins in he-patectomy for CRLM should be evaluated. In the current era of multidisciplinary treatment options, this review focused on the prognostic impact of a sub-centi/millimeter surgical margin width in hepatectomy for CRLM. We systematically reviewed retrospective studies that clearly described the sur-gical margin width for hepatectomy for CRLM. We selected studies conducted since 2000 that involved patients diag-nosed as having CRLM. We focused on studies that investi-gated not only surgical margins, but also microscopic surgical curability such as R0 (microscopically complete resection) or R1 (microscopically incomplete resection), which clearly de-scribe their definitions. Based on our literature review, 1, 2, or 5 mm was considered the minimum surgical margin width for hepatectomy for CRLM. Although a surgical margin width of 1 mm is acceptable for hepatectomy for CRLM, submil-limeter margins, which are defined as R1 in many reports, are only acceptable for limited patients such as those who have undergone preoperative chemotherapy. Zero-mm mar-gins are also acceptable in limited patients such as those who show a good response to preoperative chemotherapy. New chemotherapy agents have been reported to reduce the prognostic impact of a narrow surgical margin width. The incidence of margin recurrence, which is a major concern regarding R1 resection of CRLM, is about 20-30% according to the majority of earlier reports. As evaluations of the actual prognostic impact of the surgical margin remain difficult, fur-ther study is warranted. | Katsunori Sakamoto Toru Beppu Kohei Ogawa Kei Tamura Masahiko Honjo Naotake Funamizu Yasutsugu Takada | 2023 | Journal of Clinical and Translational Hepatology2023，11，3： | 0 |
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