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| 1 | From concept to reality-A review to the primary test stand and its preliminary application in high energy density physics显示文摘Pulsed power technology,whereas the electrical energy stored in a relative long period is released in much shorter timescale,is an efficient method to create high energy density physics(HEDP)conditions in laboratory.Around the beginning of this century,China Academy of Engineering Physics(CAEP)began to build some experimental facilities for HEDP investigations,among which the Primary Test Stand(PTS),a multi-module pulsed power facility with a nominal current of 10 MA and a current rising time~90 ns,is an important achievement on the roadmap of the electro-magnetically driven inertial confinement fusion(ICF)researches.PTS is the first pulsed power facility beyond 10 TW in China.Therefore,all the technologies have to be demonstrated,and all the engineering issues have to be overcome.In this article,the research outline,key technologies and the preliminary HEDP experiments are reviewed.Prospects on HEDP research on PTS and pulsed power development for the next step are also discussed. | Jianjun Deng Weiping Xie Shuping Feng Meng Wang Hongtao Li Shengyi Song Minghe Xia Ji Ce An He Qing Tian Yuanchao Gu Yongchao Guan Bin Wei Xianbin Huang Xiaodong Ren Jiakun Dan Jing Li Shaotong Zhou Hongchun Cai Siqun Zhang Kunlun Wang Qiang Xu Yujuan Wang Zhaohui Zhang Guilin Wang Shuai Guo Yi He Yiwei Zhou Zhanji Zhang Libing Yang Wenkang Zou | 2016 | Matter and Radiation at Extremes2016，1，1： | 19 |
| 2 | Application of next-generation sequencing technology to precision medicine in cancer: joint consensus of the Tumor Biomarker Committee of the Chinese Society of Clinical Oncology显示文摘Next-generation sequencing(NGS) technology is capable of sequencing millions or billions of DNA molecules simultaneously.Therefore, it represents a promising tool for the analysis of molecular targets for the initial diagnosis of disease, monitoring of disease progression, and identifying the mechanism of drug resistance. On behalf of the Tumor Biomarker Committee of the Chinese Society of Clinical Oncology(CSCO) and the China Actionable Genome Consortium(CAGC), the present expert group hereby proposes advisory guidelines on clinical applications of NGS technology for the analysis of cancer driver genes for precision cancer therapy. This group comprises an assembly of laboratory cancer geneticists, clinical oncologists, bioinformaticians,pathologists, and other professionals. After multiple rounds of discussions and revisions, the expert group has reached a preliminary consensus on the need of NGS in clinical diagnosis, its regulation, and compliance standards in clinical sample collection. Moreover, it has prepared NGS criteria, the sequencing standard operation procedure(SOP), data analysis, report, and NGS platform certification and validation. | Xuchao Zhang Zhiyong Liang Shengyue Wang Shun Lu Yong Song Ying Cheng Jianming Ying Weiping Liu Yingyong Hou Yangqiu Li Yi Liu Jun Hou Xiufeng Liu Jianyong Shao Yanhong Tai Zheng Wang Li Fu Hui Li Xiaojun Zhou Hua Bai Mengzhao Wang You Lu Jinji Yang Wenzhao Zhong Qing Zhou Xuening Yang Jie Wang Cheng Huang Xiaoqing Liu Xiaoyan Zhou Shirong Zhang Hongxia Tian Yu Chen Ruibao Ren Ning Liao Chunyan Wu Zhongzheng Zhu Hongming Pan Yanhong Gu Liwei Wang Yunpeng Liu Suzhan Zhang Tianshu Liu Gong Chen Zhimin Shao Binghe Xu Qingyuan Zhang Ruihua Xu Lin Shen Yilong Wu | 2019 | Cancer Biology & Medicine2019，16，1： | 14 |
| 3 | Cigarette Smoking Increases Risk for Incident Metabolic Syndrome in Chinese Men—Shanghai Diabetes Study显示文摘Objective To determine whether smoking increases the risk for developing metabolic syndrome (MetS) in Chinese men.Methods A total of 693 men with no MetS at baseline were followed for 2.9‐5.5 years.Subjects were divided into nonsmokers,ex‐smokers,and current smokers according to baseline smoking status.Results After adjusting for age,education level,alcohol intake,fasting plasma insulin,HOMA‐IR index,and BMI at baseline and weight change,current smokers were dose‐dependently associated with increased risk for developing new MetS compared with nonsmokers.The odds ratio (OR) was 2.131 (95% CI,1.264,3.592;P<0.01) for the NCEPIII definition or 3.083 (95% CI,1.807,5.295;P<0.01) for the JCDCG definition of MetS.Ex‐smokers who had quit for ≥13 years significantly decreased the risk for developing new MetS defined by the JCDCG definition.Compared with nonsmokers,current smokers were significantly associated with increased incidence of hypertriglyceridemia and low HDL‐C.Conclusion Smoking is a risk factor for developing MetS in Chinese men after adjusting for age,education level,alcohol intake,fasting plasma insulin,HOMA‐IR,BMI,and weight change.This could be due to an increased incidence of dyslipidemia.Smoking cessation for >13 years decreased the risk for developing MetS defined by the JCDCG definition. | ZHU YunXia ZHANG MingLiang HOU XuHong LU JunXi PENG LiangPu GU HuiLin WANG Chen JIA WeiPing | 2011 | Biomedical and Environmental Sciences2011，24，5： | 13 |
| 4 | The heterogeneity of islet autoantibodies and the progression of islet failure in type 1 diabetic patients显示文摘Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This study was to investigate prevalence and heterogeneity of the islet autoantibodies and clinical phenotypes of type 1 diabetes mellitus; and also discussed the process of islet failure and its risk factors in Chinese type 1 diabetic patients. A total of 1,291 type 1 diabetic patients were enrolled in this study. Demographic information was collected. Laboratory tests including mixed-meal tolerance test, human leukocyte antigen alleles, hemoglobin A1 c, lipids, thyroid function and islet autoantibodies were conducted. The frequency of islet-specific autoantibody in newly diagnosed T1 DM patients(duration shorter than half year) was 73% in East China. According to binary logistic regressions, autoantibody positivity, longer duration and lower Body Mass Index were the risk factors of islet failure. As the disease developed, autoantibodies against glutamic acid decarboxylase declined as well as the other two autoantibodies against zinc transporter 8 and islet antigen 2. The decrease of autoantibodies was positively correlated with aggressive beta cell destruction. Autoantibodies can facilitate the identification of classic T1 DM from other subtypes and predict the progression of islet failure. As there were obvious heterogeneity in autoantibodies and clinical manifestation in different phenotypes of the disease, we should take more factors into consideration when identifying type 1 diabetes mellitus. | Jin Liu Lingling Bian Li Ji Yang Chen Heng Chen Yong Gu Bingqin Ma Wei Gu Xinyu Xu Yun Shi Jian Wang Dalong Zhu Zilin Sun Jianhua Ma Hui Jin Xing Shi Heng Miao Bing Xin Yan Zhu Zhenwen Zhang Ruifang Bu Lan Xu Guangde Shi Wei Tang Wei Li Dongmei Zhou Jun Liang Xingbo Cheng Bimin Shi Jixiang Dong Ji Hu Chen Fang Shao Zhong Weinan Yu Weiping Lu Chenguang Wu Li Qian Jiancheng Yu Jialin Gao Xiaoqiang Fei Qingqing Zhang Xueqin Wang Shiwei Cui Jinluo Cheng Ning Xu Guofeng Wang Guoqing Han Chunrong Xu Yun Xie Minmin An Wei Zhang Zhixiao Wang Yun Cai Qi Fu Yu Fu Shuai Zheng Fan Yang Qingfang Hu Hao Dai Yu Jin Zheng Zhang Kuanfeng Xu Yifan Li Jie Shen Hongwen Zhou Wei He Xuqin Zheng Xiao Han Liping Yu Jinxiong She Mei Zhang Tao Yang | 2016 | Science China(Life Sciences)2016，59，9： | 5 |
| 5 | Efficacy of biofeedback therapy via a mini wireless device on sleep bruxism contrasted with occlusal splint:a pilot study显示文摘The putative causes of bruxism are multifactorial and there are no definite measures for bruxism management.The aim of this study was to evaluate the efficacy of biofeedback therapy on sleep bruxism,compared with occlusal splint.Twenty-four volunteers with sleep bruxism were divided into two groups:the GTB group that were treated with biofeedback therapy(n 512) and the GTO group that were treated with occlusal splint(n 512).A mini pressure sensor integrated with a monitoring circuit by use of a maxillary biofeedback splint was fabricated.To foster the relaxation of the masticatory muscles and the nervous system,the wireless device received signals from bruxism events and vibrations alerted the bruxer when the threshold was exceeded.Total episodes and average duration of bruxism events during8 hours of sleep were analyzed with the monitoring program(TRMY1.0).After 6 and 12 weeks,the episodes(P 50.001) and duration(P,0.05) in the GTB group declined dramatically.In contrast,there were no significant differences in the GTO group after the treatment(P.0.05).Furthermore,the episodes had significant differences between the GTB group and the GTO group after the same period of treatment(P 5 0.000).The results suggest that biofeedback therapy may be an effective and convenient measure for mild bruxers,when compared with occlusal splint therapy.The mini wireless biofeedback method may be of value for the diagnosis and management of bruxism in the future. | WeiPing Gu Jie Yang FeiMin Zhang XinMin Yin XiaoLong Wei Chen Wang | 2015 | The Journal of Biomedical Research2015，29，2： | 4 |
| 6 | Tensile and fatigue behavior of corroded rebars显示文摘 | Weiping Zhang Xiaobin Song Xianglin Gu Shibin Li | 2012 | Construction and Building Materials2012，，： | 2 |
| 7 | Effective doctor-patient communication skills training optimizes functional organization of intrinsic brain architecture:a restingstate functional MRI study显示文摘We studied the influence of doctor-patient communication skills training on brain functional architecture using resting-state functional MRI(rs-fMRI) with a regional homogeneity(ReHo) method. Ten medical students participated in the study. A 1-year long doctor-patient communication skills training program was conducted. RsfMRI data were collected at baseline, one month and one year after training. There was a significant increase in the communication skills test average scores between baseline and 1-month duration of training(P<0.001). After one month of communication skills training, medical students had decreased ReHo in the right superior temporal gyrus compared with the baseline. After one year of communication skills training, students had increased ReHo in multiple regions and decreased ReHo in several regions(P <0.05, Alphasim corrected). The change of ReHo values in the superior temporal gyrus negatively correlated with the change of communication skills scale score between one month after communication skills training and baseline(r=-0.734, P= 0.036). The training program we used can be an effective approach of improving doctor-patient communication skills, and the training resulted in functional plasticity of the brain's architecture toward optimizing locally functional organization. | Bing Zhang Ling Ni Fangfang Wang Weiping Li Xin Zhang Xiaohua Gu Zuzana Nedelska Fei Chen Kun Wang Bin Zhu Renyuan Liu Jun Xu Jinfan Wang | 2017 | The Journal of Biomedical Research2017，31，6： | 2 |
| 8 | Study on effect of soaking time on the transmission of chloride ion in concrete under drying-wetting cycles显示文摘 | ZHANG Qingzhang GU Xianglin ZHANG Weiping | 2011 | Advanced Ma- terials Research2011，，261263： | 1 |
| 9 | Effects of different forms of nitrogen addition on microbial extracellular enzyme activity in temperate grassland soil显示文摘Background:Nitrogen(N)deposition alters litter decomposition and soil carbon(C)sequestration by influencing the microbial community and its enzyme activity.Natural atmospheric N deposition comprises of inorganic N(IN)and organic N(ON)compounds.However,most studies have focused on IN and its effect on soil C cycling,whereas the effect of ON on microbial enzyme activity is poorly understood.Here we studied the effects of different forms of externally supplied N on soil enzyme activities related to decomposition in a temperate steppe.Ammonium nitrate was chosen as IN source,whereas urea and glycine were chosen as ON sources.Different ratios of IN to ON(Control,10:0,7:3,5:5,3:7,and 0:10)were mixed with equal total amounts of N and then used to fertilize the grassland soils for 6 years.Results:Our results show that IN deposition inhibited lignin-degrading enzyme activity,such as phenol oxidase(POX)and peroxidase(PER),which may restrain decomposition and thus induce accumulation of recalcitrant organic C in grassland soils.By contrast,deposition of ON and mixed ON and IN enhanced most of the C-degrading enzyme activities,which may promote the organic matter decomposition in grassland soils.In addition,theβ-N-acetyl-glucosaminidase(NAG)activity was remarkably stimulated by fertilization with both IN and ON,maybe because of the elevated N availability and the lack of N limitation after long-term N fertilization at the grassland site.Meanwhile,differences in soil pH,soil dissolved organic carbon(DOC),and microbial biomass partially explained the differential effects on soil enzyme activity under different forms of N treatments.Conclusions:Our results emphasize the importance of organic N deposition in controlling soil processes,which are regulated by microbial enzyme activities,and may consequently change the ecological effect of N deposition.Thus,more ON deposition may promote the decomposition of soil organic matter thus converting C sequestration in grassland soils into a C source. | Lili Dong Björn Berg Weiping Gu Zhengwen Wang Tao Sun | 2022 | Ecological Processes2022，11，1： | 1 |
| 10 | Serum osteocalcin levels in relation to metabolic syndrome in Chinese postmenopausal women显示文摘 | Rong Yang Xiaojing Ma Xiaoping Pan Feifei Wang Yuqi Luo Chengchen Gu Yuqian Bao Weiping Jia | 2013 | Menopause: The Journal of The North American Menopause Society2013，，5： | 1 |
| 11 | Joint 2-D DOA estimation via sparse L-shaped array显示文摘 | GU Jianfeng ZHU Weiping and SWAMY M N S | 2015 | IEEE Transactions on Signal Processing2015，63，5： | 1 |
| 12 | Morphological and anatomical studies on the seedling of Myesarus minimus显示文摘 | Jia Weiping Gu Angen Wang Mao | 1993 | Cathaya1993，5，： | 1 |
| 13 | Tensile and fatigue behavior of corroded rebars显示文摘 | Zhang Weiping Song Xiaobin Gu Xianglin | 2012 | Construction and Building Materials2012，34，40： | 1 |
| 14 | Tensile and fatigue behavior of corroded rebars显示文摘 | ZHANG Weiping SONG Xiaobin GU Xianglin | 2012 | Construction and Building Materials2012，34，1： | 1 |
| 15 | Prevalence of Hyperuricemia and Gout in Mainland China from 2000 to 2014: A Systematic Review and Meta-Analysis显示文摘 | Rui Liu Cheng Han Di Wu Xinghai Xia Jianqiu Gu Haixia Guan Zhongyan Shan Weiping Teng Lorenzo Cavagna | 2015 | BioMed Research International2015，，： | 1 |
| 16 | Microwave absorption properties of fabric coated absorbing material using modified carbonyl iron power显示文摘 | Li Weiping Zhu Liqun Gu Jing | 2011 | Composites Part B:Engineering2011，42，4： | 1 |
| 17 | The Progress of IGS Analysis Center at Wuhan University显示文摘As one of the Analysis Centers(AC)of the International GNSS Service(IGS),Wuhan University(WHU)has been contributing to the IGS by providing ultra-rapid as well as rapid orbit and clock solutions for the established GPS and GLONASS since 2012.In the same year,the IGS initiated the Multi-GNSS Experiment(MGEX)to support the analysis of the emerging GNSS systems and prepare the IGS for Multi-GNSS,which includes GPS,GLONASS,the European Galileo system,the Chinese Beidou Navigation Satellite System(BDS),the Japanese Quasi-Zenith Satellite System(QZSS)and the Indian Regional Navigation Satellite System(IRNSS/NaVIC).The major products,i.e.,orbits,Earth Orientation Parameters(EOPs),satellite clock as well as attitude have also been provided by WHU since 2012.More recently,WHU has engaged the third reprocessing of IGS for generating the highly accurate station coordinates as inputs for establishment of the International Terrestrial Reference Frame(ITRF)2020 during 2019—2020.This article presents the recent major advancements of the IGS AC at Wuhan University,including precise products,real-time products,bias products,antenna phase center calibration,and the non-linear motion modeling for GNSS Reference Stations. | Weiping JIANG Qile ZHAO Min LI Jing GUO Jianghui GENG Zhao LI Shengfeng GU Qiang ZHANG Zhigang HU Na WEI | 2023 | Journal of Geodesy and Geoinformation Science2023，6，3： | 1 |
| 18 | Understanding the enhancement of catalytic performance for olefin cracking: Hydrothermally stable acids in P/HZSM-5显示文摘 | Nianhua Xue Xiangke Chen Lei Nie Xuefeng Guo Weiping Ding Yi Chen Min Gu Zaiku Xie | 2007 | Journal of Catalysis2007，，1： | 1 |
| 19 | Effects of cerium on nitrogen metabolism of peach plantlet in vitro显示文摘 | Song Weiping Hong Fashui Wan Zhigang Zhou Yuzhen Gu Fugen Xu Hongoing Yu Mingliang Chang Youhong Zhao Mizhen Su Jiale | 2003 | Biological Trace Element Research2003，，3： | 1 |
| 20 | Microwave absorption properties of fabric coated absorbing material using modified carbonyl iron power显示文摘 | Li Weiping Zhu Liqun Gu Jing | 2011 | Composites2011，42，： | 1 |
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