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| 1 | Fine mapping of locus S-b for F_1 pollen sterility in rice (Oryza sativa L.)显示文摘Hybrid sterility is the main barrier in util-izing the heterosis of subspecies in rice. A knowledge of the underlying molecular mechanism of the hybrid sterility will be useful for overcoming the barrier. In this research, the F1 pollen sterility locus, S-b, was mapped between SSR markers PSM8 and PSM202. To fine map the locus, one F2 mapping population of 3910 plants was developed using the near-isogenic lines of the locus. Ninety-seven recombinants be-tween two markers were selected. Moreover, a series of markers, including two SSR markers, two InDel markers and four CAPS markers, were developed on the region. Linkage analysis showed that marker W4 was co-segregated with locus S-b, while makers A8 and A14 were located on the two sides of the locus with a distance of 0.026 and 0.038 cM, respectively. The markers were then integrated with the se-quences of the clones of the region. Results showed that all the polymorphic markers were anchored on the three end-to-end jointed clones AC093089, AC079021 and AC134931. According to the physical information of the markers, locus S-b was finally de-limited to a region of 27 kb between A8 and A14. Seven ORFs were identified on the region based on the annotation results of RiceGAAS system. These results laid the foundation for further cloning the gene. | LI Wentao ZENG Ruizhen ZHANG Zemin DING Xiaohua ZHANG Guiquan | 2006 | Chinese Science Bulletin2006，51，6： | 12 |
| 2 | A DELLA protein complex controls the arbuscular mycorrhizal symbiosis in plants显示文摘 | Nan Yu Dexian Luo Xiaowei Zhang Junzhong Liu Wanxiao Wang Yue Jin Wentao Dong Jiyun Liu Huan Liu Weibing Yang Longjun Zeng Qun Li Zuhua He Giles E D Oldroyd Ertao Wang | 2014 | Cell Research2014，24，1： | 9 |
| 3 | Pathways related to PMA-differentiated THP1 human monocytic leukemia cells revealed by RNA-Seq显示文摘Previous analyses have reported that the human monocytic cell line THP1 can be differentiated into cells with macrophage-like characteristics by phorbol 12-myristate 13-acetate(PMA). However, little is known about the mechanism responsible for regulating this differentiation process. Here, we performed high-throughput RNA-Seq analysis to investigate the genes differently expressed in THP1 cells treated with and without PMA and examined those that may be responsible for the PMA-induced differentiation of monocytes into macrophages. We found 3,000 genes to be differentially expressed after PMA treatment. Gene ontology analysis revealed that genes related to cellular processes and regulation of biological processes were significantly enriched. KEGG analysis also demonstrated that the differentially expressed genes(DEGs) were significantly enriched in the PI3K/AKT signaling pathway and phagosome pathway. Importantly, we reveal an important role of the PI3K/AKT pathway in PMA-induced THP1 cell differentiation. The identified DEGs and pathways may facilitate further study of the detailed molecular mechanisms of THP1 differentiation. Thus, our results provide numerous potential therapeutic targets for modulation of the differentiation of this disease. | ZENG ChengWu WANG WenTao YU XiBao YANG LiJian CHEN ShaoHua LI YangQiu | 2015 | Science China(Life Sciences)2015，58，12： | 7 |
| 4 | Highly effective and reproducible surface-enhanced Raman scattering substrates based on Ag pyramidal arrays显示文摘 | Yandong Wang Nan Lu Wentao Wang Lingxiao Liu Lei Feng Zhoufang Zeng Haibo Li Weiqing Xu Zijian Wu Wei Hu Yanqing Lu Lifeng Chi | 2013 | Nano Research2013，6，3： | 6 |
| 5 | Special interstitial route can transport nanoparticles to the brain bypassing the blood-brain barrier显示文摘Nowadays,nanoparticles(NPs)are considered to be ideal tools for bioimaging and drug delivery.Although increasing research has focused on NP biodistribution,transportation in the interstitial architecture has been neglected.The entire body is connected by the interstitial architecture,which can provide a long-range and direct pathway for NP biodistribution in a nonvascular system.In this study,we report that 10-nm gold NPs injected directly into the interstitial architecture of the tarsal tunnel of rats(intervaginal space injection(ISI))were delivered to the brain without crossing the blood-brain barrier.Furthermore,NaGdF4 nanoparticles were used to explore the transportation route by magnetic resonance imaging.The results demonstrated that,after ISI,the NaGdF4 nanoparticles were transported through the perivascular interstitial space of the carotid arteries and brain vessels to the brain.This is a special nonvascular transportation route like a stream based on the interstitial architecture that provides an alternative pathway for NP biodistribution. | Nan Hu Xiaoli Shi Qiang Zhang Wentao Liu Yuting Zhu Yuqing Wang Yi Hou Yinglu Ji Yupeng Cao Qian Zeng Zhuo Ao Quanmei Sun Xiaohan Zhou Xiaochun Wu Dong Han | 2019 | Nano Research2019，12，11： | 2 |
| 6 | An essential role for PNLDC1 in piRNA 3' end trimming and male fertility in mice显示文摘 | Yue Zhang Rui Guo Yiqiang Cui Zhiping Zhu Yingwen Zhang Hao Wu Bo Zheng Qiuling Yue Shun Bai Wentao Zeng Xuejiang Guo Zuomin Zhou Bin Shen Ke Zheng Mingxi Liu Lan Ye Jiahao Sha | 2017 | Cell Research2017，27，11： | 2 |
| 7 | Nerve growth factor and inducible nitric oxide synthase expression in the mesencephalon and diencephalon, as well as visual-and auditory-related nervous tissues, in a macaque model of type 2 diabetes显示文摘The present study detected distribution and expression of nerve growth factor and inducible nitric oxide synthase in the mesencephalon and diencephalon, as well as visual- and auditory-related nervous tissues, in a macaque model of type 2 diabetes using immunohistochemistry. Results showed that nerve growth factor expression decreased, but inducible nitric oxide synthase expression increased, in the mesencephalon and diencephalon, as well as visual- and auditory- related nervous tissues. These results suggested that nerve growth factor and inducible nitric oxide synthase play an important role in regulating the development of diabetic visual- and auditory-related diseases. | Qihui Luo Wentao Liu Jingyao Chen Mingshu Wang Wen Zeng Zhengli Chen Anchun Cheng | 2012 | Neural Regeneration Research2012，7，4： | 2 |
| 8 | Robust interface layers with redox shuttle reactions suppress the dendrite growth for stable solid-state Li metal batteries显示文摘Designing a durable lithium metal anode for solid state batteries requires a controllable and uniform deposition of lithium, and the metal lithium layer should maintain a good interface contact with solid state electrolyte during cycles. In this work, we construct a robust functional interface layer on the modified LiB electrode which considerably improves the electrochemical stability of lithium metal electrode in solid state batteries. It is found that the functional interface layer consisting of polydioxolane, polyiodide ion and Li TFSI effectively restrains the growth of lithium dendrites through the redox shuttle reaction of I-/I3-and maintains a good contact between lithium anode and solid electrolyte during cycles. Benefit from these two advantages, the modified Li-B anode exhibits a remarkable cyclic performance in comparison with those of the bare Li-B anode. | Shuaibo Zeng Gowri Manohari Arumugam Wentao Li Xiahu Liu Xin Li Hai Zhong Fei Guo Yaohua Mai | 2020 | Journal of Energy Chemistry2020，29，12： | 2 |
| 9 | Prevent Small-For-Size Syndrome Using Dual Grafts in Living Donor Liver Transplantation显示文摘 | Zheyu Chen LuNan Yan Bo Li Yong Zeng TianFu Wen JiChun Zhao WenTao Wang MingQing Xu Jiayin Yang | 2009 | Journal of Surgical Research2009，，2： | 1 |
| 10 | Teaching Reform of Courses for Ideological and Political Education Based on Simulation Information Technology:Taking the Course Group of Engineering Valuation in Jiangxi Normal University for Example显示文摘In higher engineering education,professional courses and ideological and political theory courses go in the same direction,which is an important task of the current professional curriculum construction.This paper introduces the key and difficult problems in the teaching content of the course Engineering Valuation in the Department of Engineering Management and Real Estate of Jiangxi Normal University.Based on the characteristics of simulation information technology such as BIM and VR and the differences of ideological and political elements,it updates and improves the cases of courses for ideological and political education,gives full play to the synergistic effect,and realizes the'triple'talent training goal of knowledge,ability and literacy. | Wenhai ZENG Wentao ZHONG Yifeng LIANG Chen WANG Zhangsheng LIU | 2020 | Asian Agricultural Research2020，12，12： | 1 |
| 11 | Enhanced ferroelectric polarization with less wake-up effect and improved endurance of Hf_(0.5)Zr_(0.5)O_(2)thin films by implementing W electrode显示文摘This paper reports the improvement of electrical,ferroelectric and endurance of Hf_(0.5)Zr_(0.5)O_(2)(HZO)thinfilm capacitors by implementing W electrode.The W/HZO/W capacitor shows excellent pristine 2 P_(r)values of 45.1 gC/cm^(2)at±6 V,which are much higher than those of TiN/HZO/W(34.4μC/cm^(2))and W/HZO/TiN(26.9μC/cm^(2))capacitors.Notably,the maximum initial 2 P_(r)value of W/HZO/W capacitor can reach as high as 57.9μC/cm^(2)at±7.5 V.These strong ferroelectric polarization effects are ascribed to the W electrode with a fairly low thermal expansion coefficient which provides a larger in-plane tensile strain compared with TiN electrode,allowing for enhancement of o-phase formation.Moreover,the W/HZO/W capacitor also exhibits higher endurance,smaller wake-up effect(10.1%)and superior fatigue properties up to 1.5×10^(10)cycles compared to the TiN/HZO/W and W/HZO/TiN capacitors.Such improvements of W/HZO/W capacitor are mainly due to the decreased leakage current by more than an order of magnitude compared to the W/HZO/TiN capacitor.These results demonstrate that capping electrode material plays an important role in the enhancement of o-phase formation,reduces oxygen vacancies,mitigates wake-up effect and improves reliability. | Dao Wang Yan Zhang Jiali Wang Chunlai Luo Ming Li Wentao Shuai Ruiqiang Tao Zhen Fan Deyang Chen Min Zeng Jiyan Y.Dai Xubing B.Lu J-M.Liu | 2022 | Journal of Materials Science & Technology2022，，9： | 1 |
| 12 | Detection of allelic variation at the Wx locus with single-segment substitution lines in rice ( Oryza sativa L.)显示文摘 | Bin Teng Ruizhen Zeng Yicun Wang Ziqiang Liu Zemin Zhang Haitao Zhu Xiaohua Ding Wentao Li Guiquan Zhang | 2012 | Molecular Breeding2012，，： | 1 |
| 13 | Dynamic expression of nine QTLs for tiller number detected with single segment substitution lines in rice显示文摘 | Guifu Liu Ruizhen Zeng Haitao Zhu Zemin Zhang Xiaohua Ding Fangming Zhao Wentao Li Guiquan Zhang | 2009 | Theoretical and Applied Genetics2009，，3： | 1 |
| 14 | African swine fever virus MGF505-3R inhibits cGAS-STING-mediated IFN-βpathway activation by degrading TBK1显示文摘African swine fever virus(ASFV)is an important pathogen causing acute infectious disease in domestic pigs and wild boars that seriously endangers the global swine industry.As ASFV is structurally complex and encodes a large number of functional proteins,no effective vaccine has been developed to date.Thus,dissecting the mechanisms of immune escape induced by ASFV proteins is crucial.A previous study showed that the ASFV-encoded protein is an important factor in host immunity.In this study,we identified a negative regulator,MGF505-3R,that significantly downregulated cGAS/STING-and poly(dG:dC)-mediated IFN-βand interferon stimulation response element(ISRE)reporter activity and suppressed IFNB1 and IFIT2 mRNA levels.In addition,TBK1,IRF3 and IκBαphosphorylation levels were also inhibited.Mechanistically,MGF505-3R interacted with cGAS/TBK1/IRF3 and targeted TBK1 for degradation,thereby disrupting the cGAS-STING-mediated IFN-βsignaling pathway,which appears to be highly correlated with autophagy.Knockdown MGF505-3R expression enhanced IFN-βand IL-1βproduction.Taken together,our study revealed a negative regulatory mechanism involving the MGF505-3R-cGAS-STING axis and provided insights into an evasion strategy employed by ASFV that involves autophagy and innate signaling pathways. | Mingyang Cheng Jiawei Luo Yuetong Duan Yu Yang Chunwei Shi Yu Sun Yiyuan Lu Junhong Wang Xiaoxu Li Jianzhong Wang Nan Wang Wentao Yang Yanlong Jiang Guilian Yang Yan Zeng Chunfeng Wang Xin Cao | 2022 | Animal Diseases2022，2，3： | 1 |
| 15 | High-throughput quantitative detection of triple-negative breast cancer-associated expressed miRNAs by rolling circle amplification on fluorescence-encoded microspheres显示文摘Compared with other types of breast cancer,triple-negative breast cancer(TNBC)has the characteristics of a high degree of malignancy and poor prognosis.Early diagnosis of TNBC through biological markers and timely development of effective treatment methods can reduce its mortality.Many Research experiments have confirmed that some specific mi RNA expression profiles in TNBC can used as markers for early diagnosis.However,detecting the expression profiles of multiple groups of miRNAs according to traditional detection methods is complicated and consumes many samples.To address this issue,we developed a method for high-throughput,high-sensitivity quantitative detection of multiple sets of miRNAs(including mi R-16,mi R-21,mi R-92,mi R-199,and mi R-342)specifically expressed in TNBC by rolling circle amplification(RCA)on fluorescence-encoded microspheres.Through the optimization of reaction system conditions,the developed method showed an extensive linear dynamic range and high sensitivity for all five miRNAs with the lowest limit of detection of 2 fmol/L.Meanwhile,this high-throughput detection method also appeared reasonable specificity.Only in the presence of a specific target miRNA,the fluorescence signal on the correspondingly encoded microspheres is significantly increased,while the fluorescence signal on other non-correspondingly encoded microspheres is almost negligible.Furthermore,this process exhibited good recovery and reproducibility in serum.The advantages of this method allow us to more conveniently obtain the expression profiles of multiple groups of TNBC-associated mi RNAs,which is beneficial for the early detection of TNBC. | Jieyu Liu Liming Zhang Wentao Zeng Lihua Zhang Nongyue He Zhuoxuan Lu | 2023 | Chinese Chemical Letters2023，34，9： | 0 |
| 16 | Zigzag magnetic order in a novel tellurate compound Na_(4-δ)NiTeO_6 with S=1 chains显示文摘Na_(4-δ)Ni Te O_(6) is a rare example in the transition-metal tellurate family of realizing an S=1 spin-chain structure.By performing neutron powder diffraction measurements,the ground-state magnetic structure of Na_(4-δ)Ni Te O_(6) is determined.These measurements reveal that below T_N~6.8(2)K,the Ni^(2+) moments form a screwed ferromagnetic(FM)spin-chain structure running along the crystallographic a axis but these FM spin chains are coupled antiferromagnetically along the b and c directions,giving rise to a magnetic propagation vector of k=(0,1/2,1/2).This zigzag magnetic order is well supported by first-principles calculations.The moment size of Ni^(2+) spins is determined to be 2.1(1) μ_(B) at 3 K,suggesting a significant quenching of the orbital moment due to the crystalline electric field(CEF)effect.The previously reported metamagnetic transition near H_(c)~0.1 T can be understood as a field-induced spin-flip transition.The relatively easy tunability of the dimensionality of its magnetism by external parameters makes Na_(4-δ)Ni Te O_(6)a promising candidate for further exploring various types of novel spin-chain physics. | Cheng Su Xu-Tao Zeng Yi Li Nvsen Ma Zhengwang Lin Chuandi Zhang Chin-Wei Wang Ziyu Chen Xingye Lu Wei Li Xian-Lei Sheng Wentao Jin | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，9： | 0 |
| 17 | Numerical Investigations of Transverse Gradient Undulator Based on Novel Light Sources显示文摘 | Tong Zhang Guanglei Wang Haifeng Yao Dong Wang Wentao Wang Cheng Wang Zhinan Zeng Jiansheng Liu Jiuqing Wang Shuhong Wang | 2014 | Journal of Mechanics Engineering and Automation2014，4，7： | 0 |
| 18 | The m6A writers regulated by the IL-6/STAT3 inflammatory pathway facilitate cancer cell stemness in cholangiocarcinoma显示文摘Objective:Investigation of the regulatory mechanisms of cell stemness in cholangiocarcinoma(CCA)is essential for developing effective therapies to improve patient outcomes.The purpose of this study was to investigate the function and regulatory mechanism of m6A modifications in CCA cell stemness.Methods:Interleukin 6(IL-6)treatment was used to induce an inflammatory response,and loss-of-function studies were conducted using mammosphere culture assays.Chromatin immunoprecipitation,polysome profiling,and methylated RNA immunoprecipitation analyses were used to identify signaling pathways.The in vitro findings were verified in a mice model.Results:We first identified that m6A writers were highly expressed in CCAs and further showed that STAT3 directly bound to the gene loci of m6A writers,showing that IL-6/STAT3 signaling regulated expressions of m6A writers.Downregulating m6A writers prevented cell proliferation and migration in vitro and suppressed CCA tumorigenesis in vivo.Notably,the knockdown of m6A writers inhibited CCA cell stemness that was triggered by IL-6 treatment.Mechanistically,IGF2BP2 was bound to CTNNB1 transcripts,significantly enhancing their stability and translation,and conferring stem-like properties.Finally,we confirmed that the combination of m6A writers,IGF2BP2,and CTNNB1 distinguished CCA tissues from normal tissues.Conclusions:Overall,this study showed that the IL-6-triggered inflammatory response facilitated the expressions of m6A writers and cell stemness in an m6A-IGF2BP2-dependent manner.Furthermore,the study showed that m6A modification was a targetable mediator of the response to inflammation factor exposure,was a potential diagnostic biomarker for CCA,and was critical to the progression of CCA. | Hua Ye Tianqi Chen Zhancheng Zeng Bo He Qianqian Yang Qi Pan Yueqin Chen Wentao Wang | 2022 | Cancer Biology & Medicine2022，19，3： | 0 |
| 19 | Metro Ethernet Architecture Based on Multiple Self-protected Spanning Trees显示文摘 | CHEN Wentao JIN Depeng ZENG Lieguang | 2008 | Chinese Journal of Electronics2008，17，3： | 0 |
| 20 | Effects of surface vortex on the drawdown and dispersion of floating particles in stirred tanks显示文摘The effects of surface vortex on the drawdown and dispersion of floating particles in stirred tanks were investigated.Particle distribution and power consumption were analyzed by experiments and numerical simulations in both baffled and unbaffled tanks agitated by a Rushton impeller.In unbaffled tanks,a non-aggregation rule was applied and the average dispersion index was found to serve as a reasonable prediction of the full drawdown of floating particles.The critical impeller speeds in an unbaffled tank were higher than those in a tank with vertical baffles.At each immersion depth in a baffled tank,particles distributed more uniformly and more power was consumed.Comparison of snapshots of the baffled and unbaffled tanks shows that the surface vortex increases the drawdown speed while it decreases the particle distribution uniformity and power consumption.Therefore,the use of baffles to suppress the surface vortex provides for a more uniform particle distribution in stirred tanks. | Wentao Xu Yangbo Tan Meng Li Jianglong Sun De Xie Zeng Liu | 2020 | Particuology2020，18，2： | 0 |
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